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IMGVR_UViG_3300000172_000310-3300000172-SI34jun09_200mDRAFT_10025739

Arc-Vir

IMGVR_UViG_3300000172_000310-3300000172-SI34jun09_200mDRAFT_10025739

Quality

91.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-70
PDB
Domain cluster: representative
CATH (65)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 57.0 5.00e-01 100.0% 51.0%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 59.0 5.28e-01 95.7% 57.7%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 48.0 4.70e-01 94.3% 58.4%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.76 56.0 4.94e-01 90.0% 53.9%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.73 46.0 3.89e-01 100.0% 38.1%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 55.0 4.81e-01 100.0% 53.3%
1lb3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.73 62.0 4.54e-01 95.7% 37.7%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.72 50.0 4.45e-01 92.9% 51.5%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.72 62.0 3.99e-01 100.0% 21.4%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.72 61.0 5.96e-01 100.0% 84.4%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 60.0 4.28e-01 100.0% 32.8%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 58.0 5.56e-01 98.6% 76.5%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.71 53.0 4.67e-01 98.6% 54.9%
1z6oA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 60.0 4.19e-01 97.1% 30.2%
3rrkA02 1.20.1460.20 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › 0.70 61.0 4.78e-01 100.0% 49.7%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.70 60.0 5.84e-01 91.4% 84.2%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 49.0 4.86e-01 84.3% 69.9%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.70 57.0 5.21e-01 98.6% 67.4%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.69 56.0 5.89e-01 85.7% 98.4%
3ofnY00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.69 62.0 5.26e-01 100.0% 68.7%
3sjqC00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 52.0 5.00e-01 84.3% 70.0%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 61.0 4.48e-01 98.6% 54.9%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.67 60.0 5.25e-01 98.6% 73.8%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.67 61.0 4.58e-01 100.0% 55.9%
3d2eA06 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.67 58.0 4.96e-01 100.0% 60.2%
3o3mB01 1.20.1270.370 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 45.0 3.92e-01 100.0% 47.6%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.66 51.0 4.04e-01 97.1% 40.6%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.66 54.0 4.76e-01 98.6% 61.8%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.66 58.0 4.97e-01 100.0% 61.6%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 54.0 5.39e-01 88.6% 88.7%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.66 51.0 4.07e-01 85.7% 89.7%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 50.0 4.05e-01 81.4% 46.9%
8h6qD01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.65 54.0 3.57e-01 94.3% 22.8%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.65 53.0 5.34e-01 98.6% 90.3%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 54.0 3.82e-01 100.0% 29.7%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 47.0 4.85e-01 98.6% 85.9%
1zylA03 1.20.1270.170 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.64 41.0 3.66e-01 97.1% 43.7%
6wv5A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.64 49.0 3.96e-01 88.6% 42.6%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 55.0 5.34e-01 97.1% 89.9%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 55.0 4.89e-01 98.6% 66.7%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 58.0 5.49e-01 100.0% 100.0%
4xt1A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 57.0 3.74e-01 100.0% 29.2%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 53.0 4.75e-01 91.4% 67.3%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.63 55.0 4.18e-01 100.0% 50.0%
3teqB00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 56.0 4.93e-01 100.0% 79.2%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.62 56.0 5.28e-01 100.0% 90.6%
4nqwA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 51.0 5.29e-01 87.1% 95.3%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 53.0 3.49e-01 100.0% 38.6%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.60 42.0 3.48e-01 71.4% 46.4%
8h72B01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.60 54.0 3.50e-01 100.0% 22.5%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.60 41.0 3.80e-01 78.6% 55.1%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.60 43.0 4.10e-01 88.6% 63.5%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.60 51.0 4.26e-01 97.1% 55.5%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 51.0 4.96e-01 95.7% 85.7%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.60 51.0 4.28e-01 98.6% 59.2%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 39.0 4.00e-01 94.3% 72.3%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 50.0 3.74e-01 98.6% 37.1%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 48.0 4.11e-01 100.0% 56.1%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.58 49.0 4.87e-01 100.0% 90.5%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.57 45.0 4.00e-01 88.6% 58.5%
3vayA02 1.20.120.1600 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.57 44.0 4.13e-01 84.3% 98.9%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.53 46.0 4.55e-01 100.0% 94.6%
3ihuA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.52 47.0 3.75e-01 100.0% 92.8%
3gn4A00 6.10.220.10 Special › Helix non-globular › Helical scaffold and wing domains of SecA › 0.52 40.0 3.30e-01 84.3% 46.5%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.51 43.0 3.66e-01 100.0% 57.0%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2841860 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.82 71.0 5.44e-01 100.0% 44.8%
4957771 5069.1.3.137 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF7521 0.80 65.0 5.92e-01 90.0% 66.7%
4934546 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.79 68.0 4.48e-01 91.4% 26.2%
4953715 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.78 57.0 4.45e-01 100.0% 36.7%
3346014 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.77 68.0 4.41e-01 95.7% 24.1%
5024245 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.77 71.0 6.01e-01 100.0% 63.6%
3389689 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.77 68.0 5.10e-01 100.0% 42.9%
4463728 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.76 58.0 3.70e-01 100.0% 18.5%
3964503 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.76 68.0 5.14e-01 94.3% 47.3%
4860885 633.6.1.6 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C 0.76 57.0 5.01e-01 95.7% 54.3%
3972604 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.75 66.0 5.10e-01 94.3% 48.3%
4009677 5086.1.1.220 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › phage_tail_N 0.75 71.0 5.02e-01 100.0% 42.7%
3923614 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.75 66.0 5.08e-01 100.0% 52.5%
5056279 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.74 68.0 4.46e-01 100.0% 25.4%
3595288 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.74 62.0 5.25e-01 98.6% 55.8%
5036142 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.74 64.0 4.29e-01 95.7% 27.0%
4682389 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.73 64.0 4.12e-01 100.0% 21.4%
3840120 601.50.1.1 alpha bundles › Four-helical up-and-down bundle › Flagellar cap protein FliD helical bundle domain › Flagellar cap protein FliD helical bundle domain › FliD_C 0.73 65.0 4.80e-01 100.0% 98.4%
4974029 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.72 62.0 4.17e-01 100.0% 24.7%
4984959 3758.1.1.113 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › Rad50_zn_hook 0.72 64.0 4.10e-01 100.0% 21.8%
4034478 7022.1.1.1 alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › MBOAT 0.72 68.0 5.02e-01 100.0% 43.8%
3600274 633.23.1.31 alpha bundles › Bromodomain-like › Claudin › Claudin › DUF202 0.72 66.0 5.36e-01 100.0% 56.8%
3848917 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.72 65.0 6.07e-01 100.0% 81.2%
3764851 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.71 65.0 5.93e-01 100.0% 76.7%
3493358 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.71 65.0 5.95e-01 100.0% 82.2%
4624369 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.71 55.0 4.35e-01 100.0% 40.7%
5033987 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.71 60.0 3.98e-01 100.0% 22.7%
5060042 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.71 64.0 5.05e-01 100.0% 50.0%
5067253 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.71 57.0 3.83e-01 94.3% 22.9%
5062663 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.70 61.0 4.11e-01 100.0% 26.0%
3714029 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 49.0 3.67e-01 98.6% 27.9%
4259085 3755.4.1.66 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MCPsignal 0.69 62.0 4.06e-01 100.0% 60.7%
3462288 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.69 63.0 5.75e-01 100.0% 82.2%
3979725 3291.1.1.15 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF2583 0.69 60.0 5.43e-01 92.9% 73.3%
3758790 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.68 59.0 4.79e-01 97.1% 50.4%
3718482 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.68 60.0 4.52e-01 98.6% 42.7%
3753765 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.67 61.0 3.78e-01 100.0% 19.2%
3576407 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.65 59.0 4.98e-01 100.0% 60.9%
3876590 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.65 53.0 5.02e-01 95.7% 75.3%
3931422 109.1.1.16 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_6 0.65 52.0 4.11e-01 91.4% 45.8%
3290433 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.64 49.0 4.45e-01 98.6% 62.2%
5018143 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.63 52.0 3.87e-01 88.6% 86.5%
3975851 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.63 52.0 5.24e-01 90.0% 88.6%
3253427 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.62 57.0 5.25e-01 100.0% 94.3%
3787792 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.62 57.0 5.21e-01 100.0% 80.0%
4097875 3712.1.1.2 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › DUF412 0.62 50.0 4.53e-01 100.0% 64.0%
3596144 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.61 55.0 5.24e-01 97.1% 87.5%
5074957 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.60 38.0 3.86e-01 88.6% 64.3%
3721147 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.60 49.0 3.78e-01 91.4% 40.0%
3205548 632.7.1.51 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › Etd1 0.59 37.0 3.78e-01 85.7% 62.9%
1206502 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.57 45.0 4.00e-01 88.6% 58.5%
4033102 632.5.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylocoagulase › Staphylocoagulase 0.57 44.0 4.06e-01 95.7% 65.3%
3719486 2006.1.1.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.56 50.0 3.41e-01 100.0% 64.7%
5027990 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.56 50.0 4.89e-01 100.0% 92.3%
4157096 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.55 45.0 4.19e-01 90.0% 91.1%
D2 medium residues 71-130
PDB
Domain cluster: representative
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.77 69.0 6.16e-01 100.0% 78.8%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.76 59.0 5.40e-01 98.3% 64.1%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.73 65.0 4.72e-01 100.0% 53.4%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 65.0 6.11e-01 100.0% 86.3%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.72 65.0 5.29e-01 100.0% 58.7%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.72 63.0 5.86e-01 100.0% 85.5%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.72 62.0 6.27e-01 100.0% 100.0%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.71 64.0 5.16e-01 100.0% 58.0%
1ykhA00 6.10.140.200 Special › Helix non-globular › Helix Hairpins › 0.71 63.0 5.37e-01 98.3% 64.2%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 63.0 5.34e-01 100.0% 61.9%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.70 61.0 5.48e-01 100.0% 79.1%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.70 61.0 5.43e-01 100.0% 81.8%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.70 62.0 4.27e-01 100.0% 33.0%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 61.0 3.97e-01 100.0% 28.2%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 59.0 5.50e-01 98.3% 75.0%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 61.0 5.32e-01 100.0% 82.6%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.69 61.0 6.11e-01 100.0% 98.3%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.69 61.0 4.29e-01 100.0% 35.5%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 59.0 5.82e-01 100.0% 92.1%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 60.0 4.80e-01 100.0% 50.0%
8d3mA02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.68 57.0 3.78e-01 93.3% 23.7%
1r2jA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 56.0 4.29e-01 95.0% 93.1%
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 56.0 5.41e-01 98.3% 83.6%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 58.0 3.69e-01 100.0% 21.2%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 58.0 3.91e-01 100.0% 30.6%
3vbbE01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.66 56.0 4.57e-01 100.0% 76.5%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 58.0 5.31e-01 100.0% 96.2%
4p3fA00 1.10.3450.40 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain 0.66 59.0 4.09e-01 100.0% 34.7%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 56.0 4.18e-01 100.0% 42.4%
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 47.0 4.77e-01 90.0% 82.0%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 53.0 5.36e-01 98.3% 100.0%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 54.0 4.38e-01 100.0% 49.2%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.63 51.0 5.21e-01 96.7% 96.6%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.63 54.0 4.96e-01 100.0% 98.8%
3gnlB02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 50.0 4.92e-01 95.0% 83.8%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 54.0 4.37e-01 100.0% 55.1%
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 51.0 4.83e-01 96.7% 82.4%
2qvaA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.62 51.0 4.13e-01 98.3% 47.3%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.62 53.0 5.28e-01 98.3% 95.1%
2yayA02 1.20.1670.10 Mainly Alpha › Up-down Bundle › all-alpha NTP pyrophosphatase › Type II deoxyuridine triphosphatase 0.61 50.0 3.95e-01 95.0% 76.3%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.61 50.0 5.00e-01 98.3% 96.9%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 47.0 4.46e-01 91.7% 72.4%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 50.0 3.79e-01 100.0% 40.9%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 51.0 3.90e-01 100.0% 40.9%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 46.0 3.92e-01 100.0% 58.0%
2lfhA00 4.10.280.10 Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain 0.55 33.0 3.16e-01 81.7% 47.1%
4mk3A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 46.0 3.83e-01 98.3% 52.2%
1rq0A01 6.10.140.160 Special › Helix non-globular › Helix Hairpins › 0.54 44.0 4.07e-01 98.3% 73.5%
4aybA07 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.54 45.0 3.66e-01 95.0% 78.3%
2l6xA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 44.0 3.07e-01 100.0% 28.5%
4izzB02 1.10.10.1680 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › HetR, N-terminal DNA-binding domain 0.53 46.0 4.47e-01 100.0% 97.1%
3t69A02 3.30.420.310 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain 0.53 41.0 2.85e-01 88.3% 96.5%
2e5zA01 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.52 38.0 3.88e-01 85.0% 81.4%
ECOD (46)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5048862 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.75 59.0 3.60e-01 100.0% 13.9%
4563674 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.74 67.0 6.33e-01 100.0% 98.6%
4420750 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.74 66.0 6.31e-01 100.0% 98.6%
3976215 105.2.1.0 alpha duplicates or obligate multimers › HLH-like › Dimerization domain in LRIM1/APL1C › Dimerization domain in LRIM1/APL1C 0.73 67.0 4.86e-01 100.0% 39.4%
3589137 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.73 66.0 6.28e-01 100.0% 98.6%
3550353 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.73 66.0 6.46e-01 100.0% 93.8%
3739454 192.5.1.38 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › NEDD4_Bsd2 0.73 66.0 5.45e-01 100.0% 66.7%
4587769 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.72 65.0 6.35e-01 100.0% 100.0%
3708367 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.72 65.0 6.21e-01 100.0% 98.6%
4299170 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.72 65.0 6.17e-01 100.0% 95.7%
4181677 192.29.1.272 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Val_tRNA-synt_C 0.72 64.0 6.09e-01 100.0% 97.1%
4185385 605.2.1.6 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Val_tRNA-synt_C 0.72 64.0 6.10e-01 100.0% 98.6%
3416952 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.72 65.0 4.93e-01 100.0% 47.4%
3761838 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.71 60.0 4.80e-01 100.0% 48.7%
3941043 605.1.1.211 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › ATG9 0.71 62.0 3.64e-01 98.3% 12.5%
None 0.71 64.0 4.74e-01 100.0% 49.0%
3903553 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.70 61.0 4.97e-01 100.0% 61.7%
3718745 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.69 63.0 4.72e-01 100.0% 42.9%
4196235 159.1.1.1 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG 0.69 61.0 5.18e-01 100.0% 65.0%
5045310 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.69 61.0 5.85e-01 100.0% 88.6%
4986986 3633.1.1.0 alpha duplicates or obligate multimers › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor 0.69 61.0 4.20e-01 100.0% 32.7%
3855880 622.4.1.19 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › CD20 0.68 57.0 4.89e-01 100.0% 61.0%
3189774 109.4.1.119 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRF 0.68 59.0 3.93e-01 98.3% 29.6%
3691039 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.68 60.0 5.48e-01 100.0% 80.0%
5069548 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 58.0 5.73e-01 100.0% 89.2%
4045132 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.67 59.0 4.86e-01 100.0% 55.5%
3480326 109.40.1.2 alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Ctf4_C 0.67 61.0 4.74e-01 100.0% 49.6%
3810154 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.66 59.0 4.04e-01 100.0% 32.7%
5052557 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.66 56.0 3.86e-01 93.3% 29.7%
3607086 4992.1.1.0 extended segments › RelB-like › RelB-like › RelB-like 0.64 55.0 5.06e-01 100.0% 81.2%
3627449 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.64 54.0 4.75e-01 98.3% 90.5%
3440537 109.4.1.91 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec10_HB 0.64 55.0 3.61e-01 100.0% 31.5%
3676480 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 53.0 4.80e-01 100.0% 85.6%
4638470 101.1.2.311 alpha arrays › HTH › HTH › winged helix domain › RNA12 0.63 52.0 3.92e-01 100.0% 86.5%
3608012 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.62 52.0 4.73e-01 100.0% 75.3%
3563618 73.1.1.0 beta sandwiches › SMAD/FHA domain › SMAD/FHA domain › SMAD/FHA domain 0.62 52.0 4.39e-01 100.0% 69.1%
3888162 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.61 51.0 4.24e-01 100.0% 56.7%
3238851 3812.1.1.0 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE 0.61 50.0 4.35e-01 100.0% 61.0%
4029168 4984.1.1.0 alpha bundles › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain 0.61 51.0 4.03e-01 95.0% 47.7%
4947400 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.60 51.0 3.99e-01 100.0% 77.9%
3390900 174.1.1.29 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 0.60 51.0 3.83e-01 100.0% 40.0%
3331440 601.1.3.10 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › PLAC8 0.60 51.0 3.54e-01 100.0% 82.7%
3609066 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 49.0 4.09e-01 100.0% 92.2%
1927453 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.58 46.0 4.54e-01 90.0% 84.8%
3575376 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.58 46.0 4.10e-01 95.0% 98.9%
3981640 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.51 45.0 3.96e-01 100.0% 70.0%