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IMGVR_UViG_3300000193_000230-3300000193-SI47jul10_135mDRAFT_100467810

Arc-Vir

IMGVR_UViG_3300000193_000230-3300000193-SI47jul10_135mDRAFT_100467810

Quality

96.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 28-110
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.73 55.0 4.22e-01 80.7% 63.1%
1orsC00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.70 54.0 4.65e-01 83.1% 89.4%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.70 53.0 4.59e-01 79.5% 88.6%
3zheC01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 47.0 3.57e-01 72.3% 32.1%
3d85C00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.67 51.0 4.33e-01 100.0% 50.4%
5u1aL00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 57.0 4.48e-01 100.0% 47.0%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 49.0 4.28e-01 78.3% 78.3%
1j77A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.65 53.0 3.95e-01 100.0% 36.2%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.65 51.0 3.74e-01 81.9% 54.0%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 51.0 5.32e-01 89.2% 94.9%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 46.0 4.22e-01 79.5% 89.4%
3cuxA02 1.20.1220.12 Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III 0.61 53.0 4.70e-01 97.6% 75.2%
1z6oM00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 55.0 4.18e-01 100.0% 43.5%
2yayA02 1.20.1670.10 Mainly Alpha › Up-down Bundle › all-alpha NTP pyrophosphatase › Type II deoxyuridine triphosphatase 0.60 45.0 3.85e-01 79.5% 86.7%
3f1xA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.60 48.0 4.03e-01 88.0% 98.7%
4ikhA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 44.0 3.87e-01 78.3% 87.4%
6srbA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 44.0 4.06e-01 80.7% 59.6%
2wauA02 1.20.58.830 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 47.0 4.23e-01 88.0% 73.8%
7e84A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 41.0 3.67e-01 73.5% 75.6%
2hoeA03 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.58 40.0 3.39e-01 71.1% 54.5%
6l1kA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.58 49.0 3.80e-01 96.4% 60.9%
3qavA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 41.0 3.52e-01 79.5% 77.1%
5b7cA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 41.0 3.77e-01 80.7% 69.4%
1b1uA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.55 46.0 4.15e-01 96.4% 67.5%
1n1fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 48.0 3.98e-01 100.0% 54.2%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 39.0 3.23e-01 77.1% 59.3%
3fkjA02 1.10.10.2240 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.52 35.0 3.82e-01 98.8% 89.1%
1q77A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.52 41.0 3.55e-01 88.0% 79.7%
1txgA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.52 44.0 3.70e-01 98.8% 57.4%
2xvtC00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.52 42.0 4.27e-01 97.6% 93.7%
1jvmB00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 37.0 3.52e-01 78.3% 79.0%
3i2fA02 1.10.3020.10 Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) 0.50 37.0 3.53e-01 83.1% 67.4%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3613175 304.1.1.1 a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C 0.78 56.0 4.16e-01 73.5% 56.3%
3289810 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.72 56.0 4.16e-01 81.9% 55.0%
5057227 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.71 59.0 5.09e-01 100.0% 57.7%
3702967 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.70 63.0 4.77e-01 100.0% 80.0%
5075585 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.67 51.0 3.84e-01 80.7% 60.5%
4017247 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.67 51.0 3.86e-01 80.7% 61.1%
3508893 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.66 52.0 3.87e-01 84.3% 53.1%
3654557 609.1.1.1 alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg 0.66 49.0 4.19e-01 80.7% 50.0%
3486859 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 51.0 4.16e-01 81.9% 55.3%
5054868 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.66 51.0 3.83e-01 83.1% 55.6%
2387775 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.65 57.0 4.80e-01 97.6% 97.9%
3857450 5054.1.1.1 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Lig_chan 0.64 44.0 3.62e-01 72.3% 61.3%
3415622 180.1.1.1 alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 0.64 56.0 3.98e-01 100.0% 74.6%
3704188 192.15.1.1 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › VPS28 0.63 51.0 4.93e-01 88.0% 77.9%
3253981 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.62 51.0 3.64e-01 88.0% 52.1%
3768971 192.29.1.11 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA 0.62 46.0 4.20e-01 79.5% 94.5%
4986921 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.62 54.0 4.84e-01 98.8% 74.2%
4131692 3877.1.1.1 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP 0.60 53.0 3.61e-01 100.0% 80.3%
4174547 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.60 52.0 4.62e-01 100.0% 80.8%
3189774 109.4.1.119 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRF 0.60 50.0 3.59e-01 91.6% 92.9%
3589113 1075.5.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.60 52.0 3.62e-01 100.0% 56.3%
3781812 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 48.0 3.73e-01 98.8% 74.3%
4004317 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.55 48.0 4.88e-01 96.4% 97.5%
4032073 604.5.1.3 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_1_C 0.55 46.0 3.67e-01 92.8% 70.6%
3406182 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.54 46.0 4.26e-01 96.4% 97.3%
3367150 3718.1.1.0 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT 0.54 44.0 4.24e-01 96.4% 82.1%
4094317 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.54 46.0 4.29e-01 96.4% 91.4%
4641463 5050.1.1.54 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp 0.51 44.0 3.52e-01 100.0% 86.5%
3254232 171.1.1.1 alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.51 39.0 3.21e-01 84.3% 61.8%
3476280 5059.1.1.5 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA 0.51 43.0 3.32e-01 100.0% 84.3%
3576309 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.51 37.0 3.49e-01 77.1% 65.0%
4206404 103.4.1.26 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Rod-binding 0.50 35.0 3.41e-01 74.7% 90.5%
D2 medium residues 111-186
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01126.26 best Heme_oxygenase 25.6 1.40e-05 67.1% 12.8%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.70 37.0 3.29e-01 84.2% 36.4%
2gomA00 1.10.10.1270 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV 0.69 39.0 4.32e-01 76.3% 70.5%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.64 47.0 4.11e-01 78.9% 92.4%
3hjlA02 1.10.220.30 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Flagellar motor switch protein FliG, alpha-alpha superhelical domain 0.62 48.0 4.30e-01 93.4% 60.4%
2f1kC02 1.10.3660.10 Mainly Alpha › Orthogonal Bundle › 6-phosphogluconate dehydrogenase C-terminal fold › 6-phosphogluconate dehydrogenase C-terminal like domain 0.61 53.0 4.72e-01 100.0% 78.8%
4lqxA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.61 52.0 3.57e-01 100.0% 60.7%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.59 40.0 3.29e-01 71.1% 42.9%
4biuE01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.58 39.0 3.64e-01 71.1% 60.2%
1lk3A00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.57 48.0 4.12e-01 100.0% 58.8%
2lxlA00 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.57 50.0 3.93e-01 98.7% 90.2%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 41.0 3.87e-01 77.6% 75.3%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.57 39.0 3.54e-01 71.1% 58.3%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.56 41.0 3.71e-01 77.6% 74.8%
4f03B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 45.0 3.75e-01 97.4% 93.1%
3tmmA01 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.53 44.0 3.99e-01 94.7% 96.3%
1xd4A04 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.53 47.0 3.42e-01 100.0% 78.0%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.53 36.0 3.66e-01 72.4% 90.8%
5xdcB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.52 36.0 3.27e-01 72.4% 61.3%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 36.0 2.96e-01 73.7% 42.0%
3g80A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.52 35.0 3.63e-01 71.1% 82.2%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.50 36.0 3.19e-01 77.6% 68.4%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2697024 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.69 47.0 4.10e-01 71.1% 81.7%
3244102 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.59 40.0 3.57e-01 71.1% 63.6%
2572867 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.57 39.0 3.46e-01 71.1% 54.1%
3529270 632.1.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid 0.56 39.0 3.67e-01 72.4% 57.9%
3273679 207.1.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1 0.56 37.0 2.96e-01 98.7% 29.7%
3239087 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.55 37.0 3.29e-01 71.1% 71.3%
3221932 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 47.0 4.33e-01 100.0% 93.3%
3589400 192.5.1.4 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › DUF1140 0.54 41.0 3.81e-01 82.9% 88.0%
3959687 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.53 37.0 3.42e-01 72.4% 71.7%
3954540 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.53 36.0 3.25e-01 72.4% 49.1%
3466405 1075.1.2.12 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › EMP70 0.52 44.0 3.54e-01 100.0% 55.9%
3630583 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.52 35.0 3.20e-01 71.1% 70.0%
2749857 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.52 35.0 2.46e-01 71.1% 18.5%
3686439 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.51 44.0 3.19e-01 100.0% 78.3%
5081088 101.1.2.932 alpha arrays › HTH › HTH › winged helix domain › wHTH-PRTase_assc 0.50 36.0 3.55e-01 92.1% 69.9%