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IMGVR_UViG_3300000563_000521-3300000563-SL_3KL_010_SEDDRAFT_1000141234

Arc-Vir

IMGVR_UViG_3300000563_000521-3300000563-SL_3KL_010_SEDDRAFT_1000141234

Quality

59.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 181-290
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2o0yB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 43.0 5.37e-01 96.4% 93.8%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.68 28.0 3.26e-01 82.7% 51.9%
2kloA00 1.10.10.1420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DNA replication factor Cdt1, C-terminal WH domain 0.66 43.0 4.02e-01 76.4% 52.2%
4i1sB00 4.10.80.340 Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › 0.65 24.0 3.45e-01 76.4% 71.2%
4by6B00 2.30.30.1020 Mainly Beta › Roll › SH3 type barrels. › CCR4-NOT complex subunit 2/3/5, C-terminal domain 0.60 31.0 2.74e-01 78.2% 31.3%
4pkcC00 6.20.90.20 Special › Other non-globular › SH3 type barrels. › Benzylsuccinate synthase gamma subunit 0.60 22.0 3.49e-01 81.8% 90.2%
4je3B00 3.10.20.720 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.59 31.0 3.65e-01 85.5% 71.4%
3urgA02 2.30.30.530 Mainly Beta › Roll › SH3 type barrels. › Calcium binding protein CcbP, beta-barrel domain 0.59 21.0 2.79e-01 94.5% 52.4%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 33.0 3.34e-01 96.4% 53.3%
4efoA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.55 30.0 3.28e-01 75.5% 64.0%
3ecrB03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.55 29.0 3.01e-01 82.7% 53.9%
2b9dA01 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.53 19.0 2.93e-01 82.7% 79.5%
1j0gA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 30.0 3.29e-01 73.6% 67.4%
4c0kA01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.52 33.0 3.47e-01 99.1% 68.3%
1wjnA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 32.0 3.44e-01 94.5% 70.1%
2pw9A01 4.10.80.30 Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › DNA polymerase; domain 6 0.51 16.0 2.71e-01 80.0% 88.0%
1r4sA00 3.10.270.10 Alpha Beta › Roll › Urate Oxidase › Urate Oxidase; 0.51 35.0 2.62e-01 70.9% 66.7%
3i3lA02 3.30.390.160 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.50 38.0 3.66e-01 97.3% 69.6%
3h95A02 4.10.80.100 Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › 0.50 18.0 2.67e-01 89.1% 100.0%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.50 31.0 3.36e-01 74.5% 72.3%
2k2jA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.50 34.0 3.34e-01 90.9% 64.1%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4135153 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.75 28.0 3.43e-01 82.7% 52.0%
4048220 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.70 28.0 3.25e-01 80.9% 48.8%
5023443 330.4.1.0 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.68 25.0 3.23e-01 81.8% 55.4%
3670739 101.1.2.98 alpha arrays › HTH › HTH › winged helix domain › CDT1 0.59 45.0 3.92e-01 98.2% 55.0%
3665317 101.1.2.98 alpha arrays › HTH › HTH › winged helix domain › CDT1 0.58 44.0 4.14e-01 98.2% 65.2%
3254286 221.1.1.44 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Rad60-SLD 0.57 31.0 3.41e-01 75.5% 63.6%
3235222 207.1.1.127 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › PHA-1 0.57 34.0 2.28e-01 97.3% 16.5%
3754362 3426.1.1.0 beta meanders › Telethonin › Telethonin › Telethonin 0.56 25.0 3.38e-01 76.4% 78.3%
5066083 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.54 48.0 3.88e-01 97.3% 67.0%
3472467 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.53 31.0 3.73e-01 88.2% 86.7%
3740109 221.1.1.88 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › CLU_N 0.52 32.0 3.55e-01 94.5% 78.8%
5018200 2004.1.1.220 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2 0.51 43.0 2.82e-01 94.5% 39.8%
D2 medium residues 25-169
PDB