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IMGVR_UViG_3300001322_000007-3300001322-A2665W6_1007255
Arc-VirIMGVR_UViG_3300001322_000007-3300001322-A2665W6_1007255
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-92
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF22745.3 best | Nlig-Ia | 35.9 | 7.60e-09 | 56.5% | 71.4% |
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1d8cA03 | 1.20.1220.12 | Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III | 0.74 | 54.0 | 4.77e-01 | 77.2% | 93.3% |
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 50.0 | 4.97e-01 | 75.0% | 79.6% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 51.0 | 5.03e-01 | 76.1% | 81.4% |
| 2cazE00 | 1.20.1440.200 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Vps28 N-terminal domain | 0.69 | 49.0 | 4.81e-01 | 73.9% | 82.2% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 50.0 | 4.72e-01 | 75.0% | 80.6% |
| 2wmoA01 | 1.25.40.410 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DOCK DHR2 domain, lobe A | 0.69 | 40.0 | 3.52e-01 | 75.0% | 39.6% |
| 5mv9A01 | 1.25.40.530 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain | 0.68 | 42.0 | 3.36e-01 | 71.7% | 32.4% |
| 3kflA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.67 | 52.0 | 4.23e-01 | 83.7% | 88.6% |
| 4agsB04 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.65 | 48.0 | 4.25e-01 | 78.3% | 86.5% |
| 1qqtA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.64 | 47.0 | 4.08e-01 | 77.2% | 100.0% |
| 1cgnA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.63 | 46.0 | 4.19e-01 | 77.2% | 87.9% |
| 4fx5A03 | 1.20.120.1690 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 48.0 | 4.69e-01 | 83.7% | 74.0% |
| 3kmiA00 | 1.20.120.940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain | 0.61 | 47.0 | 3.87e-01 | 83.7% | 98.8% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.60 | 42.0 | 4.12e-01 | 80.4% | 66.0% |
| 1qu3A04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.60 | 44.0 | 3.81e-01 | 78.3% | 70.7% |
| 2j9wB00 | 1.20.120.1130 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain | 0.60 | 45.0 | 4.47e-01 | 80.4% | 81.8% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 46.0 | 3.72e-01 | 84.8% | 55.4% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 41.0 | 4.04e-01 | 73.9% | 65.7% |
| 2yu1A02 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 49.0 | 4.74e-01 | 91.3% | 100.0% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 46.0 | 3.63e-01 | 85.9% | 59.0% |
| 2gtvX00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.57 | 40.0 | 3.88e-01 | 84.8% | 64.4% |
| 6nsjA00 | 1.25.40.600 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter | 0.54 | 47.0 | 3.85e-01 | 100.0% | 95.1% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 40.0 | 3.75e-01 | 80.4% | 79.5% |
| 3pvuA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.53 | 39.0 | 4.09e-01 | 83.7% | 88.7% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.52 | 40.0 | 3.65e-01 | 83.7% | 68.8% |
| 3solA00 | 1.20.58.1630 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chaperone lipoprotein PulS/OutS | 0.52 | 43.0 | 4.41e-01 | 98.9% | 93.4% |
| 3dfgA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 27.0 | 3.60e-01 | 72.8% | 97.9% |
| 4edgA01 | 3.90.980.10 | Alpha Beta › Alpha-Beta Complex › DNA primase DNAg catalytic core, N-terminal domain › DNA primase, catalytic core, N-terminal domain | 0.51 | 40.0 | 3.54e-01 | 84.8% | 81.3% |
| 2iz1A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.50 | 45.0 | 3.29e-01 | 100.0% | 71.8% |
| 3n98A02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.50 | 45.0 | 3.97e-01 | 100.0% | 88.8% |
| 2js9A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.50 | 40.0 | 4.25e-01 | 100.0% | 98.8% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4208015 | 192.4.1.26 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Nlig-Ia | 0.89 | 53.0 | 6.15e-01 | 80.4% | 80.0% |
| 4043670 | 192.4.1.26 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Nlig-Ia | 0.88 | 56.0 | 6.25e-01 | 75.0% | 80.0% |
| 4051373 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.82 | 56.0 | 3.72e-01 | 79.3% | 20.0% |
| 4143426 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.78 | 58.0 | 3.89e-01 | 77.2% | 41.6% |
| 4432215 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.78 | 58.0 | 3.87e-01 | 77.2% | 41.9% |
| 4160069 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.77 | 58.0 | 3.90e-01 | 78.3% | 65.2% |
| 5045530 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.77 | 56.0 | 5.66e-01 | 75.0% | 87.8% |
| 3840047 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.76 | 56.0 | 3.77e-01 | 77.2% | 42.9% |
| 4265994 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.75 | 62.0 | 4.16e-01 | 85.9% | 76.1% |
| 4296465 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.75 | 56.0 | 3.77e-01 | 77.2% | 42.9% |
| 4566687 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.75 | 63.0 | 4.19e-01 | 88.0% | 74.2% |
| 4489850 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.74 | 63.0 | 4.14e-01 | 88.0% | 77.5% |
| 4541712 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.74 | 62.0 | 4.18e-01 | 88.0% | 77.4% |
| 4463257 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.74 | 61.0 | 4.04e-01 | 85.9% | 78.8% |
| 4064364 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.73 | 62.0 | 4.11e-01 | 88.0% | 78.1% |
| 4468528 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.71 | 57.0 | 3.83e-01 | 82.6% | 66.7% |
| 3265071 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.71 | 51.0 | 4.77e-01 | 75.0% | 78.3% |
| 3299317 | 604.1.1.96 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Bap31 | 0.67 | 46.0 | 4.18e-01 | 71.7% | 82.4% |
| 3714315 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 49.0 | 4.67e-01 | 76.1% | 75.2% |
| 4281635 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.66 | 60.0 | 4.01e-01 | 96.7% | 78.8% |
| 3544537 | 604.1.1.63 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 | 0.66 | 48.0 | 4.47e-01 | 76.1% | 89.6% |
| 4663555 | 192.29.1.183 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF28674 | 0.66 | 51.0 | 4.28e-01 | 80.4% | 81.3% |
| 3900923 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 46.0 | 4.51e-01 | 72.8% | 85.0% |
| 4507521 | 304.107.1.3 ↗ | a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › TrmE_N | 0.65 | 53.0 | 3.80e-01 | 89.1% | 45.1% |
| 4174741 | 601.1.2.77 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › FUSC | 0.63 | 49.0 | 3.98e-01 | 83.7% | 89.7% |
| 5057826 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.62 | 48.0 | 3.77e-01 | 82.6% | 71.7% |
| 3385780 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 47.0 | 4.28e-01 | 80.4% | 75.2% |
| 3944785 | 192.29.1.183 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF28674 | 0.59 | 44.0 | 3.87e-01 | 80.4% | 84.8% |
| 4997475 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.58 | 53.0 | 3.74e-01 | 100.0% | 52.9% |
| 3862622 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.58 | 45.0 | 3.38e-01 | 84.8% | 76.1% |
| 4999600 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.57 | 44.0 | 3.48e-01 | 84.8% | 61.0% |
| 3005058 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.56 | 42.0 | 3.61e-01 | 80.4% | 70.5% |
| 4643195 | 601.4.1.53 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › FUSC | 0.56 | 51.0 | 4.15e-01 | 100.0% | 58.2% |
| 4447436 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.56 | 49.0 | 3.49e-01 | 100.0% | 51.2% |
| 4107630 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.56 | 41.0 | 3.47e-01 | 80.4% | 63.5% |
| 3326569 | 1134.1.1.11 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › All-alpha_MIP2 | 0.53 | 39.0 | 3.17e-01 | 78.3% | 79.5% |
| 3293019 | 3236.1.1.1 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger | 0.52 | 46.0 | 2.99e-01 | 100.0% | 66.0% |
| 3977638 | 7516.1.1.102 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2, Glyco_trans_2_3 | 0.50 | 39.0 | 2.80e-01 | 85.9% | 57.4% |