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IMGVR_UViG_3300001567_000010-3300001567-Draft_1000075958

Arc-Vir

IMGVR_UViG_3300001567_000010-3300001567-Draft_1000075958

Quality

89.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 65-154
PDB
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2uuiA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.65 48.0 3.99e-01 77.8% 72.9%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.64 45.0 4.69e-01 73.3% 92.7%
2i53A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.63 43.0 4.03e-01 76.7% 56.8%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.63 45.0 3.89e-01 74.4% 87.1%
3buxB01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.61 48.0 4.27e-01 84.4% 85.3%
1w5sA01 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 42.0 4.24e-01 77.8% 72.7%
6vq6G02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.58 45.0 3.62e-01 84.4% 88.6%
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.58 41.0 4.09e-01 76.7% 97.9%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.57 44.0 4.00e-01 83.3% 64.2%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 42.0 3.86e-01 81.1% 73.8%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.55 45.0 3.58e-01 87.8% 89.1%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 39.0 4.12e-01 76.7% 88.7%
6k4yI00 1.10.1810.10 Mainly Alpha › Orthogonal Bundle › Anti-sigma factor AsiA › Anti-Sigma Factor A 0.54 33.0 3.39e-01 100.0% 62.5%
2e8gA01 1.20.1440.150 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.52 37.0 3.46e-01 78.9% 95.2%
1vhnA02 1.10.1200.80 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Putative flavin oxidoreducatase; domain 2 0.51 30.0 3.30e-01 74.4% 71.8%
1at9A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 42.0 3.13e-01 90.0% 45.2%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5041273 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.62 44.0 4.18e-01 73.3% 85.7%
3242683 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.62 44.0 4.43e-01 74.4% 90.0%
3510999 611.2.1.1 alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) › Cbl_N 0.61 48.0 4.34e-01 85.6% 87.2%
3371141 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.60 32.0 3.04e-01 96.7% 43.6%
3383049 4009.1.1.18 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › FPP 0.57 40.0 4.32e-01 74.4% 98.7%
3425427 4121.1.1.6 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › DUF155 0.57 44.0 3.18e-01 82.2% 60.0%
4011291 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.57 45.0 4.20e-01 85.6% 87.0%
5081700 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.57 44.0 3.60e-01 83.3% 55.8%
4009571 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 42.0 3.28e-01 81.1% 75.8%
4020585 148.1.3.17 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › MCM_lid 0.56 45.0 4.46e-01 88.9% 96.8%
3677293 160.1.1.0 alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase 0.55 42.0 3.96e-01 83.3% 93.9%
3436259 632.15.1.5 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › Rx_N 0.52 38.0 3.55e-01 78.9% 74.2%
4031309 4275.1.1.1 alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Phage_connect_1 0.50 40.0 4.08e-01 87.8% 96.7%
D2 medium residues 1-64
PDB
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3aqoA01 3.30.70.3400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.84 34.0 3.09e-01 76.6% 31.2%
1p65A00 6.10.140.90 Special › Helix non-globular › Helix Hairpins › 0.81 32.0 3.43e-01 75.0% 43.9%
2gbmA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.66 41.0 3.77e-01 73.4% 49.4%
2mh9A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 30.0 2.36e-01 82.8% 22.0%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.59 42.0 2.83e-01 75.0% 68.3%
8es5A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 38.0 3.00e-01 73.4% 94.9%
8be0A01 3.40.91.90 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain 0.54 42.0 2.91e-01 81.2% 72.3%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.53 37.0 3.55e-01 82.8% 64.8%
2nn6F00 3.30.230.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain 0.51 42.0 2.91e-01 90.6% 34.5%
6n2aA01 2.40.37.10 Mainly Beta › Beta Barrel › Lyase, Ornithine Decarboxylase; Chain A, domain 1 › Lyase, Ornithine Decarboxylase; Chain A, domain 1 0.50 35.0 2.69e-01 76.6% 83.1%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3700232 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.79 36.0 2.61e-01 75.0% 17.6%
3937161 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.78 44.0 3.88e-01 87.5% 40.0%
3798928 59.1.4.2 beta complex topology › triple barrel › triple barrel › TFIID subunits TAF1-TAF7 › DUF3591 0.65 46.0 2.76e-01 75.0% 21.3%
3938116 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.64 46.0 3.11e-01 76.6% 22.0%
3731940 633.23.1.12 alpha bundles › Bromodomain-like › Claudin › Claudin › Fig1 0.62 51.0 3.35e-01 87.5% 91.4%
2473158 5093.1.1.1 a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly 0.62 35.0 2.61e-01 85.9% 22.0%
3871096 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.58 45.0 2.94e-01 87.5% 62.8%
3626235 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.58 48.0 2.99e-01 89.1% 33.8%
4002132 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.57 52.0 3.26e-01 98.4% 97.2%
3177990 4015.1.1.1 alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 0.55 41.0 2.89e-01 87.5% 50.2%
3926162 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.55 34.0 3.20e-01 79.7% 48.2%
3574069 604.12.1.62 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DuoxA 0.54 46.0 3.69e-01 95.3% 97.6%
3839854 2498.1.1.17 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like 0.54 44.0 3.08e-01 89.1% 29.7%
3519143 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.52 47.0 2.99e-01 100.0% 59.3%
4037529 4180.1.1.1 a+b two layers › SpoVG-like › SpoVG-like › SpoVG-like › SpoVG 0.52 43.0 3.71e-01 87.5% 100.0%
3778063 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.51 40.0 3.32e-01 92.2% 100.0%
D3 medium residues 168-256
PDB
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2fwrA01 3.40.1170.30 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › 0.76 48.0 5.82e-01 80.9% 100.0%
1bqnA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.68 50.0 4.92e-01 76.4% 83.0%
1kafA00 3.90.1150.20 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription regulator MotA, C-terminal domain 0.68 52.0 4.86e-01 80.9% 80.6%
1i7qA00 3.60.120.10 Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase 0.67 60.0 3.71e-01 98.9% 87.6%
4ls9B02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.67 50.0 4.53e-01 79.8% 82.1%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.66 51.0 5.02e-01 82.0% 97.9%
3i5tB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.65 47.0 3.90e-01 76.4% 48.2%
3u02A01 3.30.70.2200 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 45.0 3.90e-01 71.9% 87.5%
4py9A02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.65 51.0 4.54e-01 84.3% 84.9%
3devA02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.65 51.0 4.63e-01 83.1% 87.1%
4a0fB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.64 46.0 3.75e-01 75.3% 41.4%
1w97L02 3.30.420.370 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › GspL cytoplasmic domain, C-terminal subdomain 0.63 42.0 4.49e-01 92.1% 80.0%
2o1uB01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.62 54.0 4.38e-01 94.4% 93.3%
4phtY02 3.30.420.370 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › GspL cytoplasmic domain, C-terminal subdomain 0.62 36.0 4.18e-01 91.0% 82.3%
5mj6A03 2.60.40.1910 Mainly Beta › Sandwich › Immunoglobulin-like › 0.61 47.0 4.93e-01 80.9% 100.0%
3eleA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 45.0 3.37e-01 78.7% 93.5%
2ehbD00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.60 41.0 3.71e-01 70.8% 88.1%
5tkwA02 3.30.420.370 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › GspL cytoplasmic domain, C-terminal subdomain 0.59 36.0 4.01e-01 92.1% 81.8%
1gc5A01 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.57 43.0 2.97e-01 83.1% 64.4%
1qnaA01 3.30.310.10 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein 0.57 39.0 3.88e-01 70.8% 97.8%
1z5hA03 2.60.40.1910 Mainly Beta › Sandwich › Immunoglobulin-like › 0.57 43.0 4.66e-01 80.9% 100.0%
2x5fA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.56 42.0 4.07e-01 83.1% 70.2%
2aujD03 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.56 31.0 3.62e-01 82.0% 77.4%
1v2dA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 39.0 3.48e-01 74.2% 53.7%
1vq8N00 3.30.420.100 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.55 45.0 3.64e-01 93.3% 51.1%
1u04A04 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 47.0 3.52e-01 96.6% 69.6%
7kfuC01 3.100.10.20 Alpha Beta › Ribosomal Protein L15; Chain: K; domain 2 › Ribosomal Protein L15; Chain: K; domain 2 › CRISPR-associated endonuclease Cas1, N-terminal domain 0.54 39.0 4.24e-01 94.4% 90.7%
3dwlA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 45.0 4.10e-01 92.1% 72.9%
4qmfB01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.53 40.0 4.19e-01 82.0% 100.0%
1egjA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 43.0 4.14e-01 87.6% 97.0%
3g9qA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.53 45.0 3.83e-01 96.6% 60.4%
4hkqA04 3.10.20.370 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.53 41.0 4.38e-01 83.1% 97.4%
7mi4A02 3.100.10.20 Alpha Beta › Ribosomal Protein L15; Chain: K; domain 2 › Ribosomal Protein L15; Chain: K; domain 2 › CRISPR-associated endonuclease Cas1, N-terminal domain 0.52 38.0 4.07e-01 94.4% 91.9%
2vefB00 3.20.20.20 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like 0.52 47.0 3.31e-01 100.0% 97.1%
7ox5A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 40.0 3.88e-01 84.3% 100.0%
4d7pA00 2.60.40.730 Mainly Beta › Sandwich › Immunoglobulin-like › SOR catalytic domain 0.51 43.0 4.20e-01 92.1% 100.0%
3s98A03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 42.0 4.18e-01 91.0% 100.0%
1iv0A00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.50 41.0 4.03e-01 92.1% 85.7%
3og6B02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 41.0 3.97e-01 89.9% 96.0%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4966680 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.81 57.0 6.61e-01 82.0% 100.0%
3533206 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.80 57.0 6.50e-01 79.8% 100.0%
3386110 306.3.1.0 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.73 59.0 5.93e-01 86.5% 91.1%
3169041 213.1.1.62 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › ATE_N+ATE_C 0.71 51.0 3.21e-01 74.2% 100.0%
5002287 306.3.1.6 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › DEAD_assoc 0.70 54.0 4.87e-01 82.0% 90.8%
4932042 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.70 49.0 4.29e-01 86.5% 47.8%
4028694 306.3.1.0 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.69 48.0 5.45e-01 76.4% 100.0%
4957290 306.2.1.3 a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor › DEAD_assoc 0.68 53.0 4.84e-01 82.0% 94.8%
3269854 306.3.1.2 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › Img2 0.68 54.0 4.95e-01 83.1% 74.3%
4934435 309.1.1.15 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc 0.67 52.0 4.56e-01 82.0% 83.1%
3988677 3696.1.1.4 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › SNF2_assoc 0.66 50.0 4.86e-01 80.9% 97.0%
3410849 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.66 46.0 4.25e-01 73.0% 69.6%
5001322 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.65 48.0 4.46e-01 78.7% 85.2%
4096132 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.65 50.0 4.63e-01 83.1% 87.0%
185162 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.65 51.0 4.56e-01 83.1% 83.5%
1065716 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.65 50.0 4.51e-01 84.3% 84.9%
5041345 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 51.0 5.35e-01 86.5% 100.0%
4962920 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.64 49.0 4.29e-01 83.1% 74.3%
4983245 242.2.1.2 a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N 0.63 47.0 5.01e-01 89.9% 93.3%
3588369 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.63 48.0 4.41e-01 83.1% 85.0%
5000228 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.61 51.0 4.31e-01 91.0% 81.4%
3223754 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.61 51.0 4.29e-01 93.3% 69.0%
3928695 220.1.1.49 beta barrels › PH domain-like › PH domain-like › PH domain-like › Carm_PH 0.60 47.0 3.97e-01 94.4% 49.0%
3727782 225.1.1.19 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › SACS 0.60 48.0 3.76e-01 88.8% 79.0%
4404464 242.3.1.1 a+b two layers › Homing endonucleases-like › DNA repair protein MutS, domain I › DNA repair protein MutS, domain I › MutS_I 0.59 50.0 4.70e-01 93.3% 82.7%
4194607 3016.1.1.10 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P 0.59 43.0 4.70e-01 98.9% 98.6%
5036936 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.59 45.0 4.56e-01 83.1% 82.2%
3588646 306.8.1.3 a+b two layers › Glucose permease domain IIB-like › TM1457-like › TM1457-like › SNF2_assoc 0.59 49.0 4.70e-01 93.3% 96.2%
3349468 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.59 44.0 4.72e-01 83.1% 97.3%
1390047 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.59 43.0 4.33e-01 83.1% 76.9%
4947795 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.59 45.0 4.79e-01 84.3% 98.7%
4589701 3016.1.1.10 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P 0.59 44.0 4.65e-01 100.0% 91.3%
5037438 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.59 44.0 4.14e-01 82.0% 86.1%
4269433 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.58 45.0 4.41e-01 84.3% 81.1%
4987901 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.58 44.0 4.18e-01 83.1% 89.1%
4997960 242.4.1.0 a+b two layers › Homing endonucleases-like › DNA polymerase II large subunit DP2 central a+b domain › DNA polymerase II large subunit DP2 central a+b domain 0.57 42.0 4.14e-01 87.6% 72.6%
3808818 3016.1.1.10 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P 0.57 45.0 4.55e-01 86.5% 87.8%
4230630 2484.1.1.11 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ribosomal_L18p 0.56 48.0 4.47e-01 95.5% 77.0%
5044387 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.56 42.0 3.90e-01 83.1% 88.3%
4971724 3239.1.1.1 alpha complex topology › Cas1 › Cas1 › Cas1 › Cas_Cas1 0.55 40.0 2.68e-01 76.4% 42.6%
5038078 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.55 38.0 3.34e-01 71.9% 90.4%
4305577 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.55 42.0 4.13e-01 84.3% 87.0%
4263340 3016.1.1.10 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › GDC-P 0.55 44.0 4.47e-01 94.4% 92.9%
3558041 11.1.1.216 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_5 0.54 43.0 4.27e-01 87.6% 89.5%
4088587 3239.1.1.1 alpha complex topology › Cas1 › Cas1 › Cas1 › Cas_Cas1 0.54 38.0 2.68e-01 74.2% 43.6%
3712060 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.53 40.0 3.26e-01 79.8% 97.6%
5004081 3239.1.1.1 alpha complex topology › Cas1 › Cas1 › Cas1 › Cas_Cas1 0.53 38.0 2.68e-01 77.5% 44.7%
3676350 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.52 40.0 3.80e-01 88.8% 68.6%
3743570 2002.1.1.4 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Alpha-amylase 0.52 45.0 2.93e-01 97.8% 88.2%
4973607 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.51 44.0 3.27e-01 98.9% 85.7%
3706484 2484.1.1.15 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › GDA1_CD39 0.51 41.0 3.01e-01 93.3% 89.8%
3388234 2006.1.2.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases 0.50 44.0 3.07e-01 100.0% 29.7%
3274666 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.50 38.0 3.78e-01 92.1% 74.7%
D4 medium residues 266-345
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2fwrA01 3.40.1170.30 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › 0.77 51.0 5.89e-01 83.7% 94.7%
1a7jA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 50.0 3.40e-01 76.2% 27.6%
2i8eA01 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 47.0 4.85e-01 73.8% 98.6%
1hi9A02 3.30.1360.130 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Dipeptide transport protein 0.66 46.0 4.76e-01 73.8% 86.8%
1d1rA00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.63 49.0 4.89e-01 86.3% 91.6%
1jg8A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 45.0 3.27e-01 80.0% 83.3%
4yhxA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.61 53.0 4.46e-01 100.0% 72.3%
4qmhA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.59 42.0 3.01e-01 75.0% 42.8%
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.54 38.0 3.65e-01 75.0% 95.8%
2kx2A00 3.30.780.30 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › 0.54 38.0 3.64e-01 75.0% 93.8%
3lfjB00 3.40.35.10 Alpha Beta › 3-Layer(aba) Sandwich › Fructose Permease › Phosphotransferase system, sorbose subfamily IIB component 0.52 40.0 3.15e-01 82.5% 78.9%
5ttjA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.50 35.0 2.64e-01 91.3% 26.7%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3229861 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.79 64.0 6.78e-01 85.0% 97.1%
5010613 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.70 53.0 5.72e-01 81.2% 98.5%
5054116 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.65 47.0 4.84e-01 76.2% 97.3%
4467547 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.64 46.0 4.94e-01 76.2% 92.3%
4956777 3696.1.1.0 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.64 54.0 5.41e-01 91.3% 98.8%
3670512 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.64 55.0 4.20e-01 100.0% 60.0%
3970639 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.63 44.0 3.99e-01 91.3% 52.7%
4563340 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.63 45.0 4.79e-01 76.2% 90.0%
4227966 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.63 44.0 4.80e-01 75.0% 90.8%
4977215 304.117.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC 0.63 45.0 4.92e-01 76.2% 100.0%
3989567 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.63 44.0 4.87e-01 78.8% 96.7%
5062191 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.60 43.0 4.42e-01 75.0% 82.4%
4951928 101.1.9.75 alpha arrays › HTH › HTH › Putative DNA-binding domain › DUF61 0.60 44.0 4.79e-01 82.5% 100.0%
4214198 304.9.1.38 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › SET_assoc 0.60 45.0 4.46e-01 82.5% 92.9%
3282379 304.163.1.4 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › PF30808 0.58 40.0 4.41e-01 73.8% 95.0%
4943233 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.57 48.0 4.53e-01 93.8% 75.0%
5070674 304.128.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB 0.57 45.0 4.33e-01 90.0% 95.8%
5030286 109.2.1.1 alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Prenyltrans 0.56 39.0 2.72e-01 73.8% 35.1%
3946500 306.1.1.1 a+b two layers › Glucose permease domain IIB-like › Glucose permease domain IIB › Glucose permease domain IIB › PTS_EIIB 0.56 40.0 4.06e-01 78.8% 77.5%
3635276 219.1.1.93 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF6540 0.56 46.0 3.89e-01 91.3% 95.6%
3520476 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.55 49.0 3.81e-01 100.0% 98.3%
4467662 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.53 38.0 3.95e-01 76.2% 92.9%
4968061 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.52 37.0 3.65e-01 76.2% 71.1%
4294681 3016.1.1.19 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › KYNU_C 0.52 37.0 3.95e-01 75.0% 95.4%
141634 7537.1.1.1 a/b three-layered sandwiches › PTS IIb component › PTS IIb component › PTS IIb component › PTSIIB_sorb 0.51 40.0 3.16e-01 83.7% 80.0%