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IMGVR_UViG_3300002123_000034-3300002123-C687J26634_1000024120

Arc-Vir

IMGVR_UViG_3300002123_000034-3300002123-C687J26634_1000024120

Quality

92.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-181
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03167.26 best UDG 57.7 1.90e-15 88.8% 88.6%
CATH (61)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6ajpA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.87 83.0 7.85e-01 98.9% 92.7%
1ui0A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.86 83.0 8.03e-01 100.0% 94.3%
2d3yA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.81 77.0 7.08e-01 100.0% 97.3%
1wywA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.79 69.0 6.45e-01 92.7% 82.4%
1mugA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.78 68.0 7.06e-01 91.0% 99.4%
2c2pA01 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.77 66.0 6.78e-01 89.3% 96.5%
1oe4A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.77 72.0 6.42e-01 100.0% 95.5%
3ikbA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.72 68.0 6.54e-01 100.0% 93.9%
3nt7A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.66 61.0 5.71e-01 100.0% 83.9%
5g5tA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.65 45.0 4.73e-01 85.4% 77.0%
2o1sB03 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.65 45.0 5.22e-01 94.9% 99.2%
2c53A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.63 58.0 5.34e-01 100.0% 88.6%
2booA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.62 57.0 5.27e-01 100.0% 87.4%
4id0A01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.60 29.0 3.88e-01 83.1% 85.9%
2aeaA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.59 49.0 4.44e-01 87.6% 100.0%
4uhwA09 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.59 25.0 3.25e-01 85.4% 67.7%
1t0bA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.59 48.0 4.36e-01 86.0% 91.3%
1j33A02 3.40.50.10210 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (CobT), large domain 0.59 48.0 4.12e-01 85.4% 99.6%
3qi7A01 3.40.50.11400 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 44.0 4.80e-01 86.0% 95.9%
1jjfA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 53.0 4.71e-01 100.0% 90.2%
1jkmA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 53.0 4.23e-01 100.0% 75.7%
3icvA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 53.0 4.48e-01 98.3% 80.9%
4x00A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 53.0 4.61e-01 100.0% 97.8%
5ao9A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 53.0 4.54e-01 100.0% 92.5%
1o0sA03 3.40.50.10380 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Malic enzyme, N-terminal domain 0.58 48.0 4.50e-01 100.0% 71.9%
1ej2A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.57 39.0 4.00e-01 79.8% 72.5%
1gkkA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 52.0 4.48e-01 100.0% 88.0%
1vkhA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 52.0 4.58e-01 100.0% 98.5%
4ms4B01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 47.0 4.30e-01 86.5% 75.0%
3aw9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 45.0 4.44e-01 86.0% 94.3%
2w3sB03 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.56 24.0 3.15e-01 86.0% 70.2%
1ptmA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.56 46.0 3.74e-01 86.5% 98.8%
6se1A01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.56 47.0 4.16e-01 88.8% 93.2%
3fnbA02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.55 51.0 4.54e-01 100.0% 98.8%
6nbrC00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 44.0 3.71e-01 86.0% 76.1%
5u4qB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 44.0 3.72e-01 85.4% 73.0%
3ialA02 3.40.50.800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain 0.55 36.0 4.23e-01 87.1% 98.3%
3e0xA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.55 50.0 4.51e-01 99.4% 100.0%
4af8A00 3.40.50.12660 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 47.0 3.90e-01 94.9% 87.1%
3e48A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 4.38e-01 85.4% 89.1%
4rv5A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 44.0 4.20e-01 86.5% 77.5%
4xfkA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 43.0 4.09e-01 86.0% 87.4%
1bmtA02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.53 39.0 4.11e-01 84.8% 84.8%
3lopA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 43.0 4.12e-01 86.0% 79.5%
4pqhA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.53 28.0 3.65e-01 100.0% 92.8%
3ne8A00 3.40.630.40 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn-dependent exopeptidases 0.53 43.0 3.96e-01 86.0% 95.6%
6ejiA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.52 42.0 4.20e-01 84.3% 100.0%
2aizP01 3.30.1330.60 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › OmpA-like domain 0.52 28.0 3.45e-01 78.7% 82.6%
4n03A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 43.0 4.03e-01 87.1% 76.1%
8c0jA01 3.40.630.40 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn-dependent exopeptidases 0.52 42.0 4.09e-01 85.4% 99.0%
1nf8A00 3.40.50.850 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like 0.52 42.0 4.00e-01 84.3% 86.5%
1m8pA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 42.0 4.16e-01 86.5% 94.0%
3g5cA01 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.51 41.0 3.95e-01 85.4% 93.7%
3bmxA02 3.40.50.1700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain 0.51 41.0 3.84e-01 85.4% 83.4%
3t1oA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 41.0 4.02e-01 85.4% 94.3%
1yp1A00 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.51 41.0 3.98e-01 85.4% 96.5%
1nw9B00 3.40.50.1460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 41.0 3.76e-01 86.5% 92.0%
2ozeA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 41.0 3.52e-01 86.0% 92.3%
4on1A02 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.50 40.0 3.91e-01 84.3% 91.8%
1iuqA02 3.40.1130.10 Alpha Beta › 3-Layer(aba) Sandwich › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase 0.50 43.0 3.74e-01 91.6% 81.2%
1cvrA02 3.40.50.1460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 41.0 3.76e-01 86.5% 90.9%
ECOD (78)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3057088 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.88 83.0 7.74e-01 98.9% 88.8%
4962559 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.87 84.0 8.31e-01 100.0% 97.8%
4937539 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.86 79.0 7.83e-01 98.9% 92.4%
3590878 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.86 82.0 7.69e-01 100.0% 99.0%
4449291 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.86 56.0 5.56e-01 86.5% 63.6%
4943408 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 82.0 7.82e-01 100.0% 93.0%
4990486 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 82.0 7.99e-01 100.0% 96.3%
4995737 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 80.0 7.70e-01 97.8% 97.4%
3386994 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.85 77.0 7.80e-01 98.3% 96.6%
4352085 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.84 81.0 7.72e-01 100.0% 92.0%
5021506 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.84 77.0 7.63e-01 98.9% 91.9%
4968429 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.84 81.0 7.88e-01 100.0% 95.8%
4318718 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.83 75.0 7.56e-01 98.3% 96.0%
3965875 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.82 69.0 7.30e-01 96.1% 98.1%
3839117 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.81 73.0 7.32e-01 100.0% 93.3%
2070922 7569.1.1.0 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like 0.79 75.0 6.36e-01 100.0% 69.5%
4235738 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.77 66.0 6.91e-01 88.8% 100.0%
4964719 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.77 73.0 6.97e-01 100.0% 92.5%
3960892 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.76 68.0 6.69e-01 93.8% 91.1%
5072275 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.74 67.0 6.68e-01 94.9% 100.0%
158456 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.73 68.0 6.82e-01 100.0% 96.2%
5066830 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.73 69.0 6.77e-01 100.0% 96.8%
136080 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.72 68.0 6.54e-01 100.0% 93.9%
4999526 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.70 65.0 6.35e-01 98.3% 99.5%
5060012 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.69 46.0 5.38e-01 87.1% 93.1%
4962185 2007.1.5.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › Asp_Glu_race 0.69 40.0 4.86e-01 70.8% 90.0%
5073583 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.68 42.0 5.19e-01 83.7% 99.1%
143142 2007.1.5.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › Asp_Glu_race 0.66 40.0 4.91e-01 80.3% 97.3%
3974162 2007.1.5.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like 0.64 50.0 5.18e-01 95.5% 85.3%
3356601 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.64 47.0 5.10e-01 96.6% 91.2%
5050815 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.63 50.0 5.33e-01 94.4% 94.8%
5007895 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.62 49.0 5.19e-01 92.1% 93.5%
4945044 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.62 51.0 5.38e-01 93.8% 95.6%
4974575 7546.1.1.1 a/b three-layered sandwiches › Glutaminase/Asparaginase N-terminal domain › Glutaminase/Asparaginase N-terminal domain › Glutaminase/Asparaginase N-terminal domain › Asparaginase 0.62 48.0 4.46e-01 88.2% 64.0%
3925784 7579.1.1.12 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Lipase_2 0.61 56.0 4.68e-01 100.0% 93.2%
4995938 2006.1.5.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Arginase/deacetylase › Arginase 0.61 49.0 4.17e-01 86.0% 97.3%
3785575 7590.1.1.0 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs 0.59 46.0 4.52e-01 86.0% 74.4%
3638813 7512.1.1.101 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_5, Glyco_trans_1_4 0.59 48.0 3.45e-01 86.0% 93.5%
3698006 7512.1.1.24 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_5 0.59 48.0 4.00e-01 86.0% 92.5%
4955804 2007.1.5.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like 0.59 47.0 4.87e-01 94.4% 90.3%
5051520 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.59 48.0 4.92e-01 93.3% 90.6%
5079738 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.59 48.0 4.52e-01 86.5% 99.1%
4365265 7512.1.1.31 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.58 48.0 4.25e-01 86.0% 87.6%
4406138 7512.1.1.31 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.58 48.0 4.30e-01 86.0% 91.7%
4075399 7512.1.1.31 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 0.58 47.0 4.33e-01 86.0% 92.3%
3781860 2007.2.3.4 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase2 0.58 37.0 3.73e-01 100.0% 62.2%
3387176 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.58 45.0 4.63e-01 82.0% 99.4%
4261364 7510.1.1.3 a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › FA_synthesis 0.57 45.0 4.76e-01 85.4% 94.8%
3970710 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.56 46.0 4.61e-01 86.0% 97.3%
5058938 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.56 44.0 4.43e-01 82.0% 96.1%
3830503 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.56 37.0 4.39e-01 79.2% 100.0%
3315815 7512.1.1.54 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Alg14 0.56 41.0 3.74e-01 80.3% 56.7%
5025709 2007.1.5.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like 0.56 45.0 4.73e-01 93.3% 95.0%
3813339 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.56 44.0 3.93e-01 82.0% 91.0%
3840840 7566.1.1.1 a/b three-layered sandwiches › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › HflX family GTPase N-terminal domain › GTP-bdg_N,GTP-bdg_M 0.55 37.0 3.44e-01 82.6% 52.7%
4588088 2003.1.3.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › DAO 0.55 45.0 4.12e-01 86.0% 97.4%
4046767 7510.1.1.3 a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › FA_synthesis 0.55 44.0 4.63e-01 85.4% 93.3%
3389835 2007.1.2.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.55 45.0 4.19e-01 86.0% 88.2%
3630015 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.55 44.0 3.85e-01 86.0% 75.3%
3708970 2007.1.2.28 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_A-cyclase_1 0.54 36.0 3.77e-01 79.2% 73.1%
4931037 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.54 44.0 4.23e-01 85.4% 100.0%
3820177 7580.1.1.1 a/b three-layered sandwiches › RibA-like › RibA-like › RibA-like › GTP_cyclohydro2 0.54 46.0 4.76e-01 89.9% 100.0%
5062843 2011.1.1.5 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Amidase_3 0.54 44.0 3.99e-01 86.0% 95.4%
4460396 7510.1.1.3 a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › FA_synthesis 0.54 44.0 4.42e-01 86.0% 85.6%
1253200 2007.1.2.13 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_6 0.54 35.0 4.00e-01 84.3% 89.1%
5045687 2007.1.5.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.54 42.0 4.46e-01 86.0% 93.5%
3938695 2007.1.2.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.54 43.0 4.04e-01 86.0% 78.7%
4618955 7510.1.1.3 a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › FA_synthesis 0.53 43.0 4.45e-01 86.0% 92.4%
4975427 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.53 38.0 4.34e-01 85.4% 100.0%
3941417 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.53 43.0 4.21e-01 85.4% 100.0%
5070267 7576.1.1.1 a/b three-layered sandwiches › Gingipain R extra N-terminal alpha/beta domain › Gingipain R extra N-terminal alpha/beta domain › Gingipain R extra N-terminal alpha/beta domain › Peptidase_C25 0.53 43.0 4.38e-01 84.3% 98.8%
3061339 2007.1.2.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.53 44.0 3.37e-01 87.6% 77.3%
3731616 2485.1.1.39 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › GST_N_2 0.53 29.0 3.62e-01 84.8% 85.5%
4099603 2488.1.1.5 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SPOUT_MTase 0.52 42.0 4.50e-01 86.0% 98.1%
3602497 2007.1.2.13 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_6 0.51 42.0 3.87e-01 86.0% 76.9%
4979017 7575.1.1.0 a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like 0.51 41.0 3.78e-01 86.0% 94.6%
4953127 2007.1.3.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.50 36.0 3.89e-01 79.2% 87.3%
5040727 2004.1.1.146 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.50 40.0 3.58e-01 82.0% 75.1%
D2 high residues 408-526
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 38.5 9.50e-10 100.0% 28.3%
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6vddA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.85 74.0 7.61e-01 95.8% 94.8%
2yw6B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 43.0 3.91e-01 85.7% 45.3%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 43.0 4.08e-01 92.4% 49.3%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 42.0 4.34e-01 93.3% 60.9%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.71 35.0 3.95e-01 77.3% 60.4%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 40.0 4.23e-01 88.2% 65.4%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.66 45.0 4.70e-01 88.2% 74.1%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 43.0 4.31e-01 91.6% 65.3%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.65 43.0 4.20e-01 96.6% 61.5%
3fb2A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 41.0 4.40e-01 88.2% 73.3%
3ajwA00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 47.0 4.48e-01 91.6% 66.4%
1qlbA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.64 36.0 3.61e-01 94.1% 54.2%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.64 47.0 4.37e-01 91.6% 62.3%
1rqgA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.63 35.0 3.27e-01 92.4% 42.4%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 40.0 4.22e-01 85.7% 73.6%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 47.0 5.10e-01 90.8% 94.0%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.61 42.0 4.48e-01 92.4% 81.6%
3c2gA02 1.10.10.1630 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sys-1 C-terminal domain-like 0.61 24.0 3.12e-01 81.5% 61.8%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 36.0 3.92e-01 83.2% 70.3%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.59 39.0 3.21e-01 91.6% 37.0%
1sxjB03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.59 27.0 3.06e-01 80.7% 52.2%
1hciA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 37.0 3.68e-01 92.4% 59.5%
1zoyA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.57 35.0 3.60e-01 92.4% 62.4%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 46.0 4.24e-01 88.2% 100.0%
1aluA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 45.0 4.07e-01 86.6% 100.0%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 47.0 4.90e-01 92.4% 98.2%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 45.0 3.73e-01 89.9% 80.0%
2juaA00 1.20.1480.30 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein 0.54 44.0 4.71e-01 85.7% 100.0%
1yf2A02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.53 45.0 4.74e-01 88.2% 99.1%
4wpcA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 46.0 3.41e-01 93.3% 65.0%
2q9rA01 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.51 40.0 3.38e-01 83.2% 50.8%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3964115 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.85 74.0 7.20e-01 92.4% 83.1%
3608652 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.78 69.0 6.27e-01 92.4% 76.0%
4317199 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.72 42.0 4.13e-01 89.9% 54.4%
3978380 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.71 43.0 4.03e-01 93.3% 49.7%
5084060 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.69 43.0 3.88e-01 91.6% 48.4%
3637899 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.69 43.0 4.53e-01 91.6% 69.1%
1251943 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.67 39.0 3.92e-01 95.8% 54.4%
3740210 603.1.1.105 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 0.64 40.0 3.73e-01 93.3% 50.0%
5082442 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 48.0 4.69e-01 91.6% 71.5%
5064040 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 49.0 3.94e-01 92.4% 45.9%
4045132 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.63 47.0 4.96e-01 91.6% 83.6%
3786522 604.6.1.22 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 0.63 38.0 4.02e-01 87.4% 66.4%
5069745 606.1.1.1 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.62 54.0 5.62e-01 91.6% 100.0%
4289721 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.60 47.0 5.15e-01 91.6% 96.0%
3305747 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.55 49.0 4.56e-01 92.4% 77.1%
5081618 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 47.0 4.74e-01 91.6% 88.3%
3801950 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.54 47.0 3.84e-01 91.6% 57.6%
3896917 207.1.1.24 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_8 0.53 42.0 3.01e-01 92.4% 30.0%
3184584 603.1.1.100 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.53 37.0 3.57e-01 71.4% 83.0%
4973020 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.53 37.0 3.04e-01 71.4% 41.4%
3192731 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 38.0 3.58e-01 73.1% 93.6%
3516178 5086.1.1.171 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › LMBR1 0.53 45.0 3.97e-01 91.6% 67.1%
3564696 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.52 43.0 4.60e-01 85.7% 100.0%
4134003 3939.1.1.141 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › USHBP1_PDZ-bd 0.51 43.0 3.92e-01 86.6% 68.7%
5013670 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.50 42.0 3.64e-01 92.4% 58.9%
D3 medium residues 187-308
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01612.27 best DNA_pol_A_exo1 27.3 4.10e-06 96.7% 61.3%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7sxqA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.87 80.0 6.09e-01 100.0% 47.2%
6vddD01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.84 71.0 6.12e-01 95.1% 59.3%
1bdp001 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.84 69.0 5.83e-01 100.0% 54.1%
1d8yA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.82 77.0 6.15e-01 98.4% 56.7%
1yt3A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 70.0 5.90e-01 98.4% 57.2%
1qssA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 56.0 5.18e-01 99.2% 57.1%
2e6mA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 74.0 6.30e-01 100.0% 64.0%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 72.0 5.47e-01 100.0% 44.3%
3safB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 71.0 5.33e-01 100.0% 41.4%
1vk0A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 74.0 6.12e-01 100.0% 74.0%
7jw6A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 72.0 5.89e-01 100.0% 58.6%
7jw2A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.76 70.0 5.74e-01 98.4% 59.5%
4okeA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.69 52.0 4.72e-01 77.9% 80.0%
4ilkA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 34.0 3.36e-01 89.3% 53.7%
2olsA04 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.54 48.0 3.57e-01 98.4% 71.2%
1b7eA01 3.90.350.10 Alpha Beta › Alpha-Beta Complex › Transposase Inhibitor Protein From Tn5; Chain A, domain 1 › Transposase Inhibitor Protein From Tn5; Chain A, domain 1 0.53 44.0 3.56e-01 91.0% 89.0%
1ac5A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 46.0 3.13e-01 100.0% 89.2%
4gicA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.51 43.0 4.14e-01 93.4% 98.6%
5bt8A02 3.40.50.1260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate kinase, N-terminal domain 0.51 45.0 3.79e-01 100.0% 63.9%
1u04A04 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.51 38.0 3.21e-01 80.3% 75.4%
4n6fA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 37.0 3.04e-01 95.1% 38.4%
2qu8A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 40.0 3.52e-01 88.5% 83.0%
ECOD (80)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4029824 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.87 80.0 5.87e-01 100.0% 41.8%
3778350 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.86 77.0 5.83e-01 100.0% 44.2%
4367091 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 68.0 4.91e-01 95.9% 33.1%
2579558 2484.1.1.96 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_polI_exo1 0.85 75.0 6.23e-01 100.0% 56.4%
3163747 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 80.0 5.11e-01 98.4% 25.1%
3715980 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.85 79.0 6.06e-01 99.2% 60.0%
4339694 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 70.0 4.54e-01 100.0% 22.6%
3165932 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 74.0 6.01e-01 100.0% 52.6%
1236883 2484.1.1.96 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_polI_exo1 0.84 69.0 6.04e-01 100.0% 59.7%
3600160 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 76.0 5.79e-01 95.1% 69.9%
3283743 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.84 75.0 5.32e-01 100.0% 34.3%
4037090 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 80.0 6.38e-01 100.0% 55.9%
3400709 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 78.0 5.97e-01 100.0% 48.2%
4677993 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 79.0 6.32e-01 99.2% 57.7%
4031810 2484.1.1.96 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_polI_exo1 0.84 70.0 5.88e-01 100.0% 54.9%
4233346 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 78.0 5.53e-01 98.4% 36.4%
3980678 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 79.0 5.58e-01 100.0% 37.6%
3965745 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.83 79.0 5.87e-01 100.0% 45.8%
3274022 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.83 76.0 5.78e-01 99.2% 45.9%
3261268 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.83 77.0 5.21e-01 97.5% 33.8%
3661219 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.83 75.0 6.00e-01 100.0% 52.0%
3817603 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.82 78.0 5.11e-01 100.0% 29.8%
4541130 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 69.0 5.82e-01 98.4% 56.3%
3598787 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.82 77.0 5.80e-01 99.2% 56.1%
4329924 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.82 77.0 5.92e-01 100.0% 49.4%
3266621 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.82 75.0 6.73e-01 98.4% 86.7%
3359530 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 77.0 5.56e-01 100.0% 44.6%
3635955 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 76.0 5.89e-01 100.0% 50.8%
4025342 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 76.0 5.92e-01 99.2% 81.2%
3412738 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 76.0 5.94e-01 100.0% 55.0%
4028967 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 73.0 5.11e-01 100.0% 32.8%
3665458 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 76.0 6.28e-01 100.0% 60.9%
3730951 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 73.0 5.56e-01 96.7% 46.4%
1187764 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 72.0 5.48e-01 100.0% 44.3%
3961715 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 72.0 6.21e-01 100.0% 64.4%
4018545 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 75.0 5.60e-01 100.0% 48.2%
1756776 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 71.0 5.23e-01 100.0% 39.0%
3798192 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 75.0 5.95e-01 100.0% 88.3%
3997031 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 75.0 5.99e-01 100.0% 90.2%
5068292 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.80 58.0 4.90e-01 80.3% 47.2%
3193711 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 74.0 5.81e-01 98.4% 51.5%
3366300 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.80 75.0 6.08e-01 100.0% 60.6%
3236261 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 74.0 5.74e-01 100.0% 52.0%
3819346 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 74.0 6.98e-01 100.0% 86.9%
3388110 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.79 74.0 5.28e-01 100.0% 37.6%
3940277 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 73.0 5.82e-01 100.0% 54.1%
4028087 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 74.0 5.97e-01 99.2% 89.3%
3275838 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 74.0 5.76e-01 100.0% 58.4%
3434621 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 71.0 5.28e-01 100.0% 41.8%
3360497 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 73.0 6.07e-01 100.0% 67.5%
3435062 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 72.0 5.86e-01 100.0% 85.0%
3818775 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 72.0 5.84e-01 100.0% 84.1%
3528675 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 72.0 5.70e-01 100.0% 57.4%
2117499 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 73.0 6.04e-01 100.0% 74.0%
3317395 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 72.0 5.59e-01 100.0% 54.4%
3212254 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 71.0 5.60e-01 100.0% 59.2%
3685910 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 72.0 5.88e-01 100.0% 72.1%
3585591 896.1.1.0 a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.77 55.0 6.42e-01 73.8% 100.0%
3942728 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.77 59.0 4.83e-01 79.5% 58.1%
2725515 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 71.0 5.78e-01 100.0% 58.9%
4026151 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.76 72.0 5.88e-01 100.0% 62.4%
3936953 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 71.0 5.23e-01 100.0% 82.3%
3994654 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.76 70.0 5.49e-01 100.0% 60.0%
3313728 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.76 59.0 6.48e-01 88.5% 100.0%
3578004 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.75 70.0 5.34e-01 100.0% 50.6%
3839957 102.1.1.4 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc 0.75 67.0 4.81e-01 100.0% 34.7%
3510945 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.75 69.0 5.71e-01 100.0% 77.6%
3937660 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.75 69.0 5.29e-01 100.0% 54.7%
3893443 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.74 58.0 4.65e-01 80.3% 60.9%
3922908 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.74 69.0 5.52e-01 100.0% 54.8%
3515806 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.74 62.0 5.99e-01 100.0% 79.3%
4290521 2484.1.1.91 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Exu_RNase_H_like 0.73 56.0 4.26e-01 79.5% 55.1%
1866795 2484.1.1.91 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Exu_RNase_H_like 0.72 55.0 4.43e-01 79.5% 64.2%
3927943 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 66.0 5.18e-01 100.0% 51.6%
3683968 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 60.0 5.50e-01 90.2% 72.3%
3962916 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 51.0 4.77e-01 77.9% 85.6%
3940915 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.69 64.0 4.97e-01 100.0% 68.4%
3234793 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.68 63.0 5.70e-01 100.0% 76.1%
3898521 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 49.0 3.48e-01 93.4% 39.2%
4322616 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.57 45.0 3.63e-01 88.5% 44.8%
D4 medium residues 309-398
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6f1eA01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.60 39.0 3.37e-01 91.1% 42.4%
3wscA00 1.20.1420.20 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif 0.60 45.0 3.36e-01 82.2% 96.8%
2yqrA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.57 44.0 4.23e-01 82.2% 87.4%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 40.0 3.47e-01 91.1% 48.0%
4bojA00 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.53 38.0 2.62e-01 76.7% 89.0%
1r85A00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.52 45.0 3.04e-01 98.9% 55.5%
6oi7A01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.51 39.0 3.07e-01 94.4% 38.3%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4602904 6091.1.1.0 alpha bundles › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase › Helical bundle domain in Endo-alpha-N-acetylgalactosaminidase 0.61 46.0 4.77e-01 80.0% 85.9%
3252293 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.55 41.0 2.87e-01 86.7% 22.5%
3690868 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 45.0 3.00e-01 100.0% 86.7%
D5 medium residues 576-707
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 78.3 8.10e-22 98.5% 32.3%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4xviA01 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.86 79.0 7.64e-01 95.5% 90.3%
4dsfA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.86 62.0 6.81e-01 95.5% 88.2%
7r0kA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.86 77.0 7.06e-01 94.7% 94.6%
7pbkB02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.77 69.0 6.87e-01 96.2% 92.6%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.76 69.0 6.70e-01 95.5% 91.0%
4x0qA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.75 67.0 6.55e-01 95.5% 91.0%
2k60A02 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.59 32.0 4.16e-01 71.2% 100.0%
4xxiA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.57 40.0 3.90e-01 72.0% 72.8%
6zhiB02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 28.0 3.44e-01 75.0% 74.7%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.55 40.0 3.94e-01 74.2% 82.9%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 34.0 3.67e-01 91.7% 77.7%
2zc2A00 1.10.10.630 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DnaD domain-like 0.51 25.0 3.06e-01 72.7% 73.3%
2x3mA00 1.25.40.670 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 38.0 3.59e-01 78.0% 74.1%
4dwnA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.51 32.0 3.62e-01 76.5% 84.5%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4975020 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.93 86.0 8.57e-01 95.5% 93.3%
4024558 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.91 82.0 8.06e-01 97.0% 87.9%
3969341 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.90 76.0 7.87e-01 86.4% 95.2%
3654151 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.90 86.0 7.80e-01 98.5% 97.6%
4456463 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.90 78.0 7.90e-01 89.4% 93.8%
4169333 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.90 78.0 8.04e-01 89.4% 96.8%
4027630 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 76.0 8.00e-01 88.6% 96.7%
3277186 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 74.0 7.69e-01 86.4% 98.4%
3562851 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.89 85.0 8.24e-01 100.0% 95.9%
3259994 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 83.0 8.36e-01 97.0% 98.5%
3386797 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 85.0 6.90e-01 100.0% 58.9%
3711347 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 84.0 8.18e-01 98.5% 95.0%
4217329 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 75.0 7.91e-01 87.9% 98.3%
3001792 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.88 74.0 7.83e-01 87.1% 97.5%
3333780 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 82.0 8.00e-01 97.7% 96.4%
3595646 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 80.0 7.55e-01 97.0% 96.1%
3423772 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 68.0 7.26e-01 80.3% 97.4%
4237263 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.86 74.0 7.74e-01 88.6% 99.2%
4617703 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.86 71.0 7.00e-01 85.6% 96.4%
3595356 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.86 73.0 7.58e-01 88.6% 96.0%
3483301 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.86 79.0 7.54e-01 96.2% 97.3%
4876668 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.84 69.0 7.17e-01 85.6% 95.2%
3581048 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.82 79.0 7.39e-01 100.0% 88.4%
2970332 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.81 77.0 7.51e-01 100.0% 95.8%
3703169 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.81 69.0 6.40e-01 88.6% 96.2%
4848450 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.80 76.0 7.47e-01 100.0% 98.6%
3785892 4964.1.1.2 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol 0.80 74.0 5.90e-01 98.5% 99.6%
3740693 101.1.21.1 alpha arrays › HTH › HTH › HTH in T7 RNA polymerase › RPOL_N 0.80 73.0 4.60e-01 98.5% 32.4%
4995740 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.78 63.0 6.48e-01 84.8% 98.4%
4506746 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.72 61.0 5.33e-01 90.2% 96.3%
167309 592.2.1.3 alpha arrays › PWI domain-like › YugE-like › YugE-like › Nab2 0.66 41.0 4.48e-01 72.0% 76.2%
3992442 592.7.1.1 alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain › GIPC1_GH2 0.63 40.0 4.73e-01 76.5% 96.5%
3631439 592.7.1.0 alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain 0.58 41.0 4.64e-01 78.8% 100.0%
3960328 2004.1.1.49 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase 0.57 48.0 4.12e-01 92.4% 73.1%
3950240 2004.1.1.49 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase 0.57 48.0 3.83e-01 95.5% 66.9%
3551714 592.6.1.2 alpha arrays › PWI domain-like › Pre-mRNA-splicing helicase BRR2 plug domain › Pre-mRNA-splicing helicase BRR2 plug domain › PF26582 0.55 41.0 4.48e-01 87.9% 99.0%
4530835 2004.1.1.226 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADDB_N 0.55 47.0 3.74e-01 93.9% 78.9%
4930259 2006.1.1.18 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 0.55 44.0 3.78e-01 86.4% 80.5%
5049790 2004.1.3.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.54 39.0 3.49e-01 73.5% 65.4%
4927999 141.1.1.0 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases 0.52 44.0 3.28e-01 93.9% 81.9%
4587778 101.1.2.25 alpha arrays › HTH › HTH › winged helix domain › FUR 0.51 44.0 4.59e-01 93.9% 100.0%
3396058 3361.1.1.1 alpha bundles › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › RAC_head 0.51 26.0 3.09e-01 84.8% 70.0%
D6 medium residues 708-798
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 53.8 2.10e-14 92.3% 22.8%
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.78 67.0 5.70e-01 94.5% 75.8%
1y10B02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.77 66.0 5.14e-01 92.3% 78.1%
2wz1B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.74 65.0 5.11e-01 98.9% 86.2%
2rqkA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.71 51.0 4.84e-01 92.3% 63.3%
4wp3C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.70 60.0 4.74e-01 94.5% 76.5%
3ungC03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.69 60.0 5.31e-01 95.6% 88.7%
3aqoA01 3.30.70.3400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 48.0 5.08e-01 80.2% 85.0%
1ybtB00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 58.0 4.73e-01 97.8% 83.1%
1s7hA01 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 46.0 4.85e-01 85.7% 83.7%
2cg4A02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.66 45.0 4.65e-01 76.9% 76.2%
1r8gA00 3.30.590.20 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › 0.65 53.0 3.51e-01 87.9% 92.0%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 47.0 4.90e-01 76.9% 85.2%
3eucA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.64 49.0 4.30e-01 96.7% 54.0%
2zbcA01 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.64 43.0 4.70e-01 80.2% 86.3%
6n3dA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 45.0 4.65e-01 93.4% 83.7%
1bd3A00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 43.0 3.27e-01 75.8% 79.0%
8d3mA02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.60 45.0 3.35e-01 81.3% 88.3%
3sqgB02 3.30.70.470 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 49.0 4.27e-01 92.3% 71.7%
4p6qA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 43.0 4.54e-01 89.0% 89.7%
1zpwX00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 40.0 4.14e-01 83.5% 78.0%
3ftbA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 46.0 4.34e-01 96.7% 68.8%
6opmD01 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.58 44.0 3.29e-01 81.3% 61.3%
3thxB04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.58 43.0 3.89e-01 96.7% 56.2%
3l09A03 3.30.70.2670 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 29.0 3.51e-01 78.0% 87.2%
5jldA01 3.30.1360.70 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Arginyl tRNA synthetase N-terminal domain 0.56 42.0 4.00e-01 82.4% 72.8%
1uu1B01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.56 48.0 4.21e-01 98.9% 64.1%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.56 40.0 4.00e-01 75.8% 81.1%
2h2yA01 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.56 45.0 4.19e-01 87.9% 75.0%
5yk4A04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.55 41.0 3.70e-01 96.7% 53.7%
1x23B00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.55 46.0 3.93e-01 93.4% 59.9%
1e6vB02 1.20.840.10 Mainly Alpha › Up-down Bundle › Methyl-coenzyme M Reductase; Chain B, domain 2 › Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal 0.54 43.0 3.01e-01 84.6% 42.9%
4tzmB00 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.53 39.0 2.98e-01 79.1% 76.7%
2gs8A02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.53 42.0 3.67e-01 86.8% 90.0%
6wngA02 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.52 39.0 2.85e-01 82.4% 87.5%
1go4A00 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.51 44.0 3.49e-01 96.7% 84.2%
5ly3A02 3.30.420.570 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.51 41.0 3.17e-01 91.2% 86.2%
6nifA01 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.50 42.0 3.35e-01 96.7% 86.8%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4975021 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.90 81.0 8.24e-01 93.4% 100.0%
3386797 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.90 81.0 5.85e-01 95.6% 38.4%
3338638 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.87 72.0 7.47e-01 86.8% 100.0%
3485236 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.83 75.0 6.35e-01 95.6% 70.7%
4566363 304.120.1.18 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › Inhibitor_I9 0.78 52.0 5.67e-01 86.8% 82.7%
3962112 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.73 65.0 5.02e-01 95.6% 73.7%
4974053 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.73 50.0 5.43e-01 83.5% 86.7%
3164240 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.72 52.0 5.86e-01 85.7% 100.0%
4507561 3012.1.1.9 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › SecD_1st 0.71 54.0 4.48e-01 86.8% 47.1%
3603411 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.71 35.0 3.06e-01 98.9% 31.9%
3164241 304.28.1.4 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.71 53.0 5.38e-01 84.6% 80.0%
5060029 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.69 48.0 4.95e-01 82.4% 76.5%
5072747 304.120.1.6 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.69 45.0 5.28e-01 74.7% 100.0%
5045103 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.68 46.0 5.00e-01 80.2% 85.3%
4339025 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.68 56.0 4.18e-01 89.0% 97.3%
4940473 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.67 52.0 5.26e-01 83.5% 83.3%
3640563 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.67 51.0 5.47e-01 86.8% 97.3%
4140340 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.67 34.0 2.88e-01 96.7% 29.3%
3283323 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.67 47.0 4.89e-01 82.4% 78.8%
5025259 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.66 42.0 4.74e-01 78.0% 90.8%
4983091 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.65 34.0 2.97e-01 95.6% 33.3%
3224222 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.65 43.0 4.40e-01 87.9% 70.0%
4983135 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.63 48.0 4.99e-01 82.4% 96.5%
4015693 859.1.1.0 a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 0.63 45.0 3.37e-01 74.7% 74.7%
3722814 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.61 48.0 4.62e-01 94.5% 73.3%
3485857 304.9.1.69 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_DGKtheta 0.61 46.0 4.54e-01 85.7% 75.8%
3709607 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.61 36.0 2.87e-01 100.0% 30.9%
3604080 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.61 43.0 4.35e-01 83.5% 73.1%
3637847 243.1.1.2 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 0.61 33.0 3.38e-01 93.4% 52.2%
3383967 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 42.0 4.34e-01 89.0% 78.8%
3555106 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.59 46.0 3.19e-01 96.7% 24.1%
5051087 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.59 33.0 3.11e-01 96.7% 44.5%
3939311 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.59 34.0 3.17e-01 91.2% 45.5%
3612078 304.9.1.23 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_5 0.59 43.0 3.92e-01 82.4% 56.0%
4181668 5054.1.1.7 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › KdpA 0.58 43.0 4.04e-01 76.9% 95.5%
3789405 859.1.1.0 a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 0.58 44.0 3.29e-01 80.2% 48.7%
4624584 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.58 45.0 3.11e-01 97.8% 24.5%
3244833 3914.1.1.2 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer 0.58 47.0 2.82e-01 91.2% 84.6%
3990034 101.1.2.92 alpha arrays › HTH › HTH › winged helix domain › HTH_11 0.57 37.0 3.73e-01 94.5% 65.6%
3789599 859.1.1.0 a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 0.57 42.0 3.30e-01 78.0% 81.0%
3617960 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.56 47.0 4.15e-01 92.3% 70.4%
3790375 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.56 35.0 3.18e-01 91.2% 45.6%
3953277 243.1.1.26 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_4 0.55 43.0 3.74e-01 84.6% 92.4%
4169639 4018.1.1.1 a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › FBPase 0.54 46.0 3.66e-01 96.7% 53.5%
3511614 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.54 35.0 3.72e-01 75.8% 75.0%
4338987 602.1.1.1 alpha arrays › L-aspartase middle domain-like › L-aspartase middle domain-like › L-aspartase middle domain-like › Lyase_1 0.53 42.0 3.05e-01 85.7% 71.0%
3446982 243.1.1.2 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 0.53 44.0 3.85e-01 91.2% 93.3%
3352429 859.1.1.1 a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › HORMA 0.52 38.0 2.99e-01 76.9% 80.0%
3452455 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.51 36.0 3.91e-01 84.6% 97.1%
4936444 2006.1.1.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3 0.51 41.0 3.17e-01 89.0% 53.2%
4067342 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.51 40.0 2.70e-01 84.6% 63.3%
4025746 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.50 39.0 3.22e-01 83.5% 78.8%