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IMGVR_UViG_3300002123_000073-3300002123-C687J26634_1000121811

Arc-Vir

IMGVR_UViG_3300002123_000073-3300002123-C687J26634_1000121811

Quality

91.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-59
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2mx8A01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.68 55.0 4.60e-01 96.6% 57.5%
2wzkA02 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.67 58.0 4.58e-01 100.0% 60.6%
4ga6A02 1.20.970.50 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › 0.65 52.0 3.82e-01 100.0% 34.2%
1iv8A04 1.10.10.470 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Maltooligosyl trehalose synthase; domain 4 0.64 52.0 4.58e-01 96.6% 74.2%
2c42A03 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.64 53.0 3.74e-01 98.3% 28.8%
3on3B00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.62 51.0 3.74e-01 98.3% 32.0%
4he8D00 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.61 43.0 3.18e-01 74.6% 34.4%
2vxdA00 1.10.10.2100 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Nucleophosmin, C-terminal domain 0.61 50.0 5.19e-01 94.9% 98.1%
3h20A04 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.60 47.0 4.32e-01 100.0% 64.0%
2elcA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.59 46.0 4.45e-01 93.2% 76.1%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.59 45.0 4.05e-01 86.4% 60.5%
1d0cA03 3.90.1230.10 Alpha Beta › Alpha-Beta Complex › Bovine Endothelial Nitric Oxide Synthase Heme Domain; Chain: A,domain 3 › Nitric Oxide Synthase; Chain A, domain 3 0.58 47.0 4.23e-01 96.6% 82.0%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 46.0 3.69e-01 98.3% 94.3%
3hklA00 1.10.2000.10 Mainly Alpha › Orthogonal Bundle › Frizzled cysteine-rich domain › Frizzled cysteine-rich domain 0.57 49.0 3.80e-01 100.0% 78.7%
1or4B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 47.0 3.63e-01 100.0% 98.7%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.57 41.0 3.74e-01 76.3% 94.8%
1yozA00 1.10.3200.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like 0.56 48.0 3.96e-01 98.3% 72.6%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 41.0 3.41e-01 76.3% 46.0%
3k3uA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 47.0 3.72e-01 98.3% 97.1%
5dllA05 1.25.50.10 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain 0.56 49.0 3.13e-01 100.0% 71.7%
5xdcB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.56 46.0 3.92e-01 100.0% 55.9%
1e7uA05 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.56 44.0 3.23e-01 93.2% 69.1%
7nc3F01 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 46.0 3.75e-01 93.2% 70.2%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.55 45.0 4.29e-01 100.0% 87.7%
2o36A01 1.20.1050.40 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 0.54 46.0 3.70e-01 100.0% 64.8%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.54 47.0 3.91e-01 100.0% 64.2%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 37.0 3.51e-01 81.4% 57.7%
2jpnA00 1.20.1280.210 Mainly Alpha › Up-down Bundle › Monooxygenase › Uncharacterised protein UvsW.1 0.53 43.0 4.04e-01 100.0% 75.9%
6q9jB02 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.53 38.0 3.37e-01 76.3% 95.5%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.52 42.0 3.30e-01 91.5% 71.1%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.52 37.0 3.58e-01 76.3% 70.1%
6tkyA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.52 46.0 3.63e-01 100.0% 68.9%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.52 37.0 3.64e-01 78.0% 74.2%
5xfaA04 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.51 39.0 3.49e-01 84.7% 64.7%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 42.0 3.92e-01 93.2% 82.7%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4115604 2003.1.5.82 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.76 66.0 4.13e-01 96.6% 24.2%
3261028 198.1.1.2 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 0.76 65.0 5.87e-01 100.0% 74.1%
3273958 198.1.1.10 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2, SapB_1, Saposin 0.74 63.0 5.67e-01 98.3% 72.9%
3959976 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.72 66.0 4.82e-01 100.0% 51.3%
3706800 129.1.1.0 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.71 61.0 4.90e-01 100.0% 48.3%
5066592 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.69 59.0 4.99e-01 96.6% 77.0%
3512862 593.1.1.1 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 0.69 58.0 3.89e-01 96.6% 39.6%
4407331 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.68 56.0 5.27e-01 98.3% 90.7%
3484228 4030.1.1.0 alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz 0.67 51.0 5.20e-01 100.0% 92.7%
5045360 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.67 57.0 4.74e-01 100.0% 90.0%
4024318 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.66 56.0 5.05e-01 98.3% 78.8%
4934293 4993.1.1.0 extended segments › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit 0.65 55.0 5.04e-01 96.6% 71.2%
3274085 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.64 53.0 5.11e-01 100.0% 81.4%
3477054 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.63 52.0 5.17e-01 96.6% 98.4%
3925313 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.63 43.0 4.00e-01 72.9% 61.3%
3587779 138.1.1.0 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain 0.62 42.0 3.87e-01 72.9% 52.5%
3694374 7579.1.1.44 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_6 0.59 49.0 3.30e-01 94.9% 68.2%
3897957 198.1.1.10 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2, SapB_1, Saposin 0.59 52.0 4.74e-01 100.0% 78.8%
3164823 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.57 50.0 3.38e-01 100.0% 68.7%
3471151 210.1.3.1 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_2 0.57 49.0 3.38e-01 96.6% 57.0%
3605793 604.9.1.0 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 0.56 46.0 4.33e-01 93.2% 81.3%
4009705 639.2.1.0 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.55 42.0 4.21e-01 84.7% 88.3%
3921644 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 37.0 2.93e-01 74.6% 32.6%
5067071 604.17.1.0 alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like 0.52 45.0 4.44e-01 100.0% 96.9%
D2 medium residues 60-110
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.70 47.0 4.36e-01 70.6% 65.6%
3kdqA00 6.10.320.10 Special › Helix non-globular › Ferritin › 0.69 46.0 3.29e-01 70.6% 26.3%
5cofA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.68 53.0 3.59e-01 84.3% 40.7%
3v93F01 1.10.1300.10 Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 0.60 42.0 2.51e-01 72.5% 13.3%
4jzyA02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 50.0 3.69e-01 100.0% 64.5%
2pg4A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 44.0 3.66e-01 88.2% 60.4%
3e22A03 1.10.287.600 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.56 37.0 3.70e-01 70.6% 85.2%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3607851 9.15.1.1 beta barrels › Lipocalins/Streptavidin › TLDC domain of oxidation resistance protein 2 › TLDC domain of oxidation resistance protein 2 › TLD 0.82 55.0 3.42e-01 70.6% 22.6%
3598082 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.80 58.0 3.58e-01 76.5% 16.2%
4012307 3008.1.1.0 a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.79 55.0 5.02e-01 72.5% 83.1%
3670801 282.1.1.1 a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS 0.77 52.0 3.45e-01 70.6% 69.7%
3507860 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.73 50.0 3.87e-01 70.6% 56.2%
3794543 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.67 52.0 4.81e-01 84.3% 98.5%
3736627 109.4.1.1379 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30880 0.67 57.0 3.32e-01 96.1% 24.5%
3332625 101.1.2.498 alpha arrays › HTH › HTH › winged helix domain › PF25870 0.52 39.0 3.28e-01 82.4% 88.4%