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IMGVR_UViG_3300002223_000396-3300002223-C687J26845_1000305911

Arc-Vir

IMGVR_UViG_3300002223_000396-3300002223-C687J26845_1000305911

Quality

83.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 3-41
PDB
Domain cluster: representative
CATH (68)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3bpvA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.95 59.0 3.85e-01 100.0% 18.2%
4zudA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.76 51.0 3.05e-01 97.4% 10.5%
7sk7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.76 54.0 3.26e-01 97.4% 11.9%
2oap202 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.75 51.0 3.03e-01 100.0% 10.1%
1p4xA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.75 67.0 4.59e-01 100.0% 54.3%
3obaA03 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.75 54.0 3.17e-01 79.5% 12.8%
1wp1B01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.74 56.0 3.24e-01 84.6% 66.2%
1k8kA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.73 48.0 3.63e-01 71.8% 28.3%
2fbhA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 56.0 3.71e-01 84.6% 75.2%
1p4xA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 63.0 4.39e-01 100.0% 57.7%
1xexB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 51.0 3.47e-01 94.9% 20.5%
1vq0A02 3.90.1280.10 Alpha Beta › Alpha-Beta Complex › CBS domain Like › HSP33 redox switch-like 0.69 48.0 4.28e-01 84.6% 50.9%
5eriA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 59.0 3.88e-01 94.9% 52.3%
3oqgA00 3.40.1440.50 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › 0.67 45.0 2.96e-01 71.8% 65.3%
2xadA00 3.40.50.10320 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › LmbE-like 0.66 55.0 3.31e-01 89.7% 35.9%
4l80D00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.66 52.0 3.05e-01 89.7% 25.6%
4hn3A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.66 54.0 3.23e-01 100.0% 11.7%
7jgsG02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 46.0 3.49e-01 89.7% 30.6%
1fx2A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 48.0 3.00e-01 79.5% 41.3%
4s1hA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.65 54.0 3.19e-01 92.3% 33.8%
4l8nA03 3.30.160.670 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.65 47.0 3.04e-01 92.3% 17.1%
8agaA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 53.0 3.84e-01 100.0% 57.1%
6aqgD02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.65 54.0 3.16e-01 97.4% 61.7%
2ebnA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.65 55.0 3.24e-01 92.3% 26.3%
1mhyD00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.65 57.0 3.17e-01 100.0% 21.2%
7dvrA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 52.0 3.63e-01 97.4% 53.9%
7r0kA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.64 51.0 3.46e-01 97.4% 47.6%
3rhtA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.64 52.0 3.14e-01 89.7% 77.0%
3akjA02 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.63 53.0 3.29e-01 100.0% 17.9%
1cnzA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.63 46.0 2.72e-01 82.1% 31.4%
4hjwA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.63 51.0 2.87e-01 100.0% 9.1%
7l9pK01 3.30.900.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain 0.63 53.0 3.73e-01 94.9% 37.8%
3llcA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.63 47.0 2.83e-01 92.3% 12.3%
4rayA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.63 46.0 4.29e-01 82.1% 64.0%
2j42A02 2.60.120.240 Mainly Beta › Sandwich › Jelly Rolls › Protective antigen, heptamerisation domain 0.62 43.0 2.91e-01 76.9% 44.8%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.62 55.0 3.55e-01 97.4% 40.7%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.62 56.0 3.08e-01 100.0% 17.2%
2f1rA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 40.0 2.70e-01 97.4% 15.5%
4p04A01 2.60.40.3100 Mainly Beta › Sandwich › Immunoglobulin-like › Arylsulphate sulphotransferase monomer, N-terminal domain 0.61 41.0 3.12e-01 71.8% 27.4%
2r1fA03 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.61 51.0 5.19e-01 100.0% 92.3%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.61 54.0 4.03e-01 97.4% 78.7%
5ck3C00 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.61 45.0 3.45e-01 87.2% 55.2%
2qx2A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.61 53.0 3.15e-01 100.0% 12.3%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.60 52.0 3.91e-01 97.4% 79.3%
3gr5A02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.59 54.0 4.40e-01 100.0% 95.6%
3h95A02 4.10.80.100 Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › 0.59 40.0 4.08e-01 84.6% 93.3%
4p1mB01 3.30.160.880 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Cell division protein ZapA protomer, N-terminal domain 0.59 52.0 4.96e-01 97.4% 86.7%
5r0dB01 2.60.34.20 Mainly Beta › Sandwich › Substrate Binding Domain Of DNAk; Chain A, domain 1 › 0.59 42.0 3.08e-01 87.2% 24.5%
6pcoC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 47.0 3.42e-01 100.0% 52.3%
1u9pA00 1.10.1220.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › Met repressor-like 0.58 42.0 3.36e-01 87.2% 35.4%
6r9rA01 3.40.50.10640 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SSO1389-like 0.58 44.0 2.82e-01 84.6% 73.0%
5sviB00 3.30.40.100 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.58 36.0 3.34e-01 74.4% 41.5%
3ephA03 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.57 48.0 4.26e-01 92.3% 83.3%
4bmjA00 6.20.250.40 Special › Other non-globular › Double Stranded RNA Binding Domain › 0.57 40.0 3.55e-01 76.9% 67.7%
2y8yA02 3.30.70.1210 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 2 0.57 49.0 3.57e-01 100.0% 67.8%
2bm0A03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.56 42.0 3.80e-01 87.2% 60.8%
5yvxA00 3.30.40.100 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.56 35.0 3.10e-01 74.4% 38.3%
1gpqB00 3.40.1420.10 Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › Inhibitor of vertebrate lysozyme 0.55 38.0 2.72e-01 71.8% 85.9%
3mk7C01 6.10.280.130 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 46.0 3.51e-01 100.0% 51.1%
3lxqA01 3.30.1120.80 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.52 43.0 3.42e-01 97.4% 38.4%
1z1bA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.52 47.0 4.10e-01 100.0% 70.2%
1rmdA02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.52 36.0 3.82e-01 97.4% 93.3%
2czrA02 3.90.79.30 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › TBP-interacting protein, C-terminal domain 0.51 38.0 2.89e-01 92.3% 97.5%
3l9fA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 40.0 3.25e-01 97.4% 83.1%
1nh8A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 41.0 3.45e-01 89.7% 88.1%
3fdfA02 6.10.140.550 Special › Helix non-globular › Helix Hairpins › 0.51 36.0 3.19e-01 89.7% 44.6%
4uy8X00 2.30.170.40 Mainly Beta › Roll › Ribosomal Protein L24e; Chain: T; › Ribosomal protein L28/L24 0.51 35.0 3.07e-01 82.1% 89.6%
4ijdA02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.50 33.0 3.62e-01 82.1% 80.6%
ECOD (67)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4959043 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.88 76.0 5.26e-01 100.0% 30.0%
3684015 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.85 54.0 3.91e-01 100.0% 26.0%
3799597 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.84 54.0 3.99e-01 100.0% 30.6%
4991835 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.83 59.0 5.45e-01 76.9% 60.0%
3988478 857.1.1.1 a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.81 56.0 4.07e-01 100.0% 28.6%
3600598 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.73 60.0 4.05e-01 89.7% 79.3%
3788781 246.2.1.7 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › DNA_pol_E_B 0.73 56.0 3.16e-01 82.1% 33.7%
3921728 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.72 55.0 3.85e-01 97.4% 27.8%
4072997 263.1.1.7 a+b three layers › SRF-like › SRF-like › SRF-like › Nrf1_DNA-bind 0.72 54.0 4.20e-01 92.3% 39.7%
3797108 2008.1.1.29 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Dna2 0.72 54.0 3.36e-01 82.1% 69.3%
3750883 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 54.0 3.50e-01 100.0% 18.9%
3482807 277.1.1.0 a+b two layers › PX domain › PX domain › PX domain 0.71 59.0 4.34e-01 100.0% 34.3%
4456198 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.70 60.0 3.91e-01 100.0% 56.2%
5045741 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.70 52.0 4.59e-01 87.2% 55.4%
4303957 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.69 61.0 4.05e-01 100.0% 26.5%
4931277 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.69 56.0 3.63e-01 87.2% 77.4%
3954346 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.68 59.0 3.54e-01 100.0% 13.6%
3466238 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.68 54.0 3.05e-01 89.7% 17.3%
5051204 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.68 48.0 4.26e-01 87.2% 50.0%
5032187 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.68 48.0 4.37e-01 84.6% 54.5%
3499344 3914.1.1.2 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer 0.68 60.0 3.21e-01 100.0% 85.9%
3958774 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.68 59.0 3.52e-01 100.0% 15.1%
3306806 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.68 45.0 4.33e-01 79.5% 60.0%
5018603 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.67 58.0 3.62e-01 100.0% 18.9%
3933447 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.67 56.0 4.13e-01 97.4% 47.6%
4937630 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.66 59.0 3.67e-01 100.0% 18.6%
3219908 109.4.1.80 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRN3 0.66 51.0 3.29e-01 84.6% 70.0%
4580635 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.65 54.0 3.26e-01 94.9% 35.4%
3512976 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.65 54.0 3.27e-01 94.9% 34.7%
4135088 101.1.2.25 alpha arrays › HTH › HTH › winged helix domain › FUR 0.65 44.0 3.00e-01 71.8% 18.7%
3595497 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 53.0 3.25e-01 94.9% 37.0%
3235875 376.1.4.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR 0.64 52.0 4.34e-01 92.3% 90.0%
3240369 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.64 54.0 3.26e-01 100.0% 36.5%
4987043 2002.1.1.73 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TGT 0.64 57.0 3.28e-01 100.0% 20.3%
4929843 4123.1.1.0 few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like 0.64 41.0 3.92e-01 74.4% 50.0%
4959999 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.64 44.0 4.34e-01 76.9% 100.0%
3614175 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.64 53.0 3.65e-01 87.2% 65.5%
3492270 11.16.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in A1 cistron-splicing factor AAR2 › N-terminal domain in A1 cistron-splicing factor AAR2 › AAR2_1st 0.63 51.0 3.40e-01 94.9% 20.0%
3180843 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.63 54.0 3.37e-01 94.9% 18.6%
3307706 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.63 46.0 3.24e-01 84.6% 88.6%
3899209 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.63 55.0 3.50e-01 100.0% 50.8%
3720343 145.1.1.1 alpha arrays › F-box domain › F-box domain › F-box domain › F-box 0.62 35.0 2.73e-01 89.7% 22.4%
3236563 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.62 56.0 3.78e-01 97.4% 39.2%
4083451 192.2.1.20 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ASNSD1-SEP 0.62 56.0 4.37e-01 100.0% 65.0%
3927286 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.61 52.0 4.30e-01 100.0% 73.3%
5012106 101.1.2.25 alpha arrays › HTH › HTH › winged helix domain › FUR 0.61 41.0 2.84e-01 79.5% 20.0%
5010744 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.61 50.0 4.27e-01 94.9% 72.3%
3882804 263.1.1.4 a+b three layers › SRF-like › SRF-like › SRF-like › PRAS_NT 0.61 49.0 4.07e-01 87.2% 84.4%
3699463 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.60 56.0 3.38e-01 100.0% 28.4%
4988512 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.60 57.0 3.53e-01 100.0% 33.7%
3904071 214.1.1.11 a+b two layers › SH2 › SH2 › SH2 › PF27628 0.60 47.0 3.51e-01 97.4% 55.8%
3812828 101.1.2.245 alpha arrays › HTH › HTH › winged helix domain › PORR 0.60 45.0 3.24e-01 79.5% 65.7%
3376010 375.3.1.1 few secondary structure elements › Rubredoxin-like › CSL zinc finger › CSL zinc finger › zf-DNL 0.59 43.0 4.01e-01 84.6% 80.0%
3490921 385.1.1.10 few secondary structure elements › Cystine-knot cytokines › Cystine-knot cytokines › Cystine-knot cytokines › Noggin 0.58 50.0 3.28e-01 100.0% 38.4%
5073703 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.58 37.0 3.38e-01 74.4% 52.0%
3784386 376.1.3.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.58 41.0 4.06e-01 82.1% 71.1%
3426409 3256.1.1.0 a+b two layers › DUF2233 N-terminal domain › DUF2233 N-terminal domain › DUF2233 N-terminal domain 0.58 40.0 4.27e-01 74.4% 96.7%
4507638 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.58 53.0 3.41e-01 100.0% 35.8%
4127397 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.56 48.0 3.96e-01 92.3% 55.4%
4197044 3433.1.2.0 a+b duplicates or obligate multimers › ParB dimerization domain › ParB dimerization domain › Chromosome-encoded ParB dimerization domain 0.56 43.0 3.98e-01 84.6% 70.0%
3991544 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 52.0 3.70e-01 100.0% 52.0%
3946510 803.1.1.0 a+b duplicates or obligate multimers › Hypothetical protein YoaG › Hypothetical protein YoaG › Hypothetical protein YoaG 0.55 44.0 4.27e-01 89.7% 97.8%
4403587 4232.1.1.1 few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 0.54 35.0 2.85e-01 74.4% 28.2%
3289385 3433.1.2.1 a+b duplicates or obligate multimers › ParB dimerization domain › ParB dimerization domain › Chromosome-encoded ParB dimerization domain › ParB_dimer 0.54 40.0 3.66e-01 79.5% 66.0%
4029085 11.16.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in A1 cistron-splicing factor AAR2 › N-terminal domain in A1 cistron-splicing factor AAR2 › AAR2_1st 0.52 39.0 2.88e-01 97.4% 31.4%
3641739 376.1.3.6 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf-CW 0.52 36.0 3.25e-01 76.9% 49.1%
5030555 3433.1.1.0 a+b duplicates or obligate multimers › ParB dimerization domain › ParB dimerization domain › Plasmid-encoded ParB dimerization domain 0.51 38.0 3.77e-01 79.5% 82.5%
D2 medium residues 49-80
PDB
Domain cluster: representative
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2dt8A01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.92 80.0 5.08e-01 100.0% 22.1%
2g7zA01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.92 81.0 5.07e-01 100.0% 21.3%
3lupA01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.89 76.0 4.81e-01 100.0% 21.3%
3nctA00 3.40.50.11880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Plasmid SOS inhibition protein 0.89 76.0 4.95e-01 100.0% 24.1%
5l3wA01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.89 75.0 5.52e-01 100.0% 38.1%
3jr7A01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.87 73.0 4.96e-01 100.0% 28.8%
3bm1A00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.87 75.0 4.62e-01 100.0% 18.6%
1ufvA02 3.30.1300.10 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › Pantoate-beta-alanine ligase, C-terminal domain 0.85 69.0 4.95e-01 100.0% 49.5%
4fcyA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.83 68.0 5.24e-01 100.0% 43.6%
2aplA01 1.10.8.330 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like 0.83 66.0 5.39e-01 100.0% 50.0%
1vhxB00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.82 69.0 4.49e-01 100.0% 22.5%
4e69A00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.79 67.0 3.87e-01 100.0% 11.0%
4k7cA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.78 65.0 3.65e-01 100.0% 8.9%
1tfeA02 1.10.286.20 Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › 0.77 62.0 5.70e-01 100.0% 75.6%
1t7lB01 3.20.20.210 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 0.77 57.0 3.21e-01 100.0% 7.1%
2gukA00 3.30.2190.10 Alpha Beta › 2-Layer Sandwich › PG1857-like › PG1857-like 0.76 55.0 3.92e-01 87.5% 25.2%
2wvxA04 1.20.1610.10 Mainly Alpha › Up-down Bundle › Glycosyl hydrolase family fold › alpha-1,2-mannosidases domains 0.76 57.0 3.57e-01 87.5% 15.6%
3k3wA02 1.10.287.150 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 56.0 5.73e-01 87.5% 100.0%
2lqxA00 6.10.250.1700 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.74 59.0 5.69e-01 100.0% 87.8%
1mv8A03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.74 56.0 3.36e-01 87.5% 12.9%
5je8B02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.74 60.0 4.09e-01 100.0% 28.1%
1vpdA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.73 62.0 4.17e-01 100.0% 26.7%
3dkqA02 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.71 57.0 5.01e-01 87.5% 66.0%
1z7mC00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.71 52.0 3.04e-01 87.5% 9.3%
2p0tA02 1.10.60.30 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › PSPTO4464-like domains 0.69 53.0 4.10e-01 87.5% 37.5%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.67 55.0 4.16e-01 100.0% 40.0%
5lbmA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.66 55.0 4.14e-01 100.0% 45.8%
7d1tA01 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.66 54.0 3.44e-01 100.0% 44.5%
1nvpB00 1.10.287.100 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 49.0 4.72e-01 100.0% 100.0%
3ne5B04 6.10.140.730 Special › Helix non-globular › Helix Hairpins › 0.65 55.0 4.82e-01 100.0% 66.7%
2yevA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 52.0 4.16e-01 100.0% 47.3%
2hcnA03 1.10.260.90 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › 0.64 47.0 3.79e-01 90.6% 39.4%
1pv0A01 1.10.287.1100 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Sporulation inhibitor A 0.63 46.0 4.62e-01 87.5% 85.3%
1oxjA01 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.62 44.0 3.79e-01 84.4% 42.6%
3zdmB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.62 52.0 4.55e-01 100.0% 70.0%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.62 52.0 4.36e-01 100.0% 96.7%
4asvA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.58 48.0 3.71e-01 100.0% 44.3%
2jbrA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.57 39.0 2.93e-01 96.9% 24.4%
1zl8B00 1.10.287.650 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain 0.55 40.0 3.70e-01 100.0% 64.8%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3721950 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.94 79.0 6.06e-01 90.6% 44.6%
3994704 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.94 83.0 6.49e-01 100.0% 50.8%
3226082 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.93 83.0 5.59e-01 100.0% 30.9%
4404896 5060.1.1.1 alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 0.93 82.0 5.46e-01 100.0% 28.7%
3372215 3226.1.1.3 alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp 0.92 80.0 4.30e-01 100.0% 5.9%
4016157 6026.1.1.1 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 0.91 80.0 5.16e-01 100.0% 25.2%
3926800 3443.1.1.0 alpha duplicates or obligate multimers › Get5 carboxyl domain › Get5 carboxyl domain › Get5 carboxyl domain 0.91 79.0 6.41e-01 100.0% 55.0%
4417274 2010.1.1.1 a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain › DegV 0.91 78.0 4.91e-01 100.0% 20.6%
3385053 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.90 79.0 4.53e-01 100.0% 12.2%
5022668 7064.1.1.1 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.89 75.0 4.88e-01 100.0% 23.6%
4010301 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.88 75.0 4.71e-01 100.0% 20.6%
3966348 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.88 75.0 5.50e-01 100.0% 40.0%
3878119 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.88 74.0 4.93e-01 100.0% 26.4%
3646394 4156.1.1.4 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C 0.87 74.0 4.84e-01 100.0% 24.4%
4088535 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.86 74.0 4.62e-01 100.0% 20.6%
4318142 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.85 74.0 4.79e-01 100.0% 24.3%
4630575 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.84 73.0 4.85e-01 100.0% 27.2%
3882597 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.83 67.0 4.96e-01 100.0% 40.0%
4337032 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.83 71.0 4.71e-01 100.0% 25.6%
4243432 2004.1.1.499 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2, Helicase_C_2 0.83 69.0 3.79e-01 100.0% 6.2%
3784055 192.24.1.0 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.82 67.0 4.51e-01 100.0% 27.7%
4328219 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.81 71.0 4.66e-01 100.0% 25.2%
3607406 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.81 65.0 5.03e-01 100.0% 46.3%
3590184 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.80 66.0 4.43e-01 100.0% 23.7%
3463858 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 64.0 4.64e-01 100.0% 38.0%
5030164 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.79 67.0 5.28e-01 100.0% 48.6%
4120017 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.79 68.0 4.44e-01 100.0% 24.3%
4060628 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.79 68.0 4.56e-01 100.0% 26.2%
3696717 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.78 62.0 3.91e-01 100.0% 28.4%
4026926 604.7.1.1 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA 0.76 62.0 4.03e-01 90.6% 23.0%
162110 616.1.1.2 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › WHEP-TRS 0.75 59.0 4.50e-01 90.6% 39.2%
3592841 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.73 58.0 4.56e-01 90.6% 44.3%
4061849 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.72 57.0 3.96e-01 90.6% 27.3%
3073109 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 55.0 4.34e-01 90.6% 41.9%
5054165 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.71 55.0 3.36e-01 90.6% 14.1%
3318561 616.1.1.2 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › WHEP-TRS 0.71 61.0 5.12e-01 100.0% 63.6%
3381499 314.1.1.1 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2 0.70 61.0 3.38e-01 100.0% 8.1%
3605626 192.12.1.0 alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM 0.70 61.0 4.24e-01 100.0% 33.3%
3660125 3711.1.1.4 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 0.70 62.0 4.54e-01 100.0% 41.2%
3396277 192.17.1.12 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › WHEP-TRS 0.70 60.0 4.95e-01 100.0% 58.3%
4935885 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.70 60.0 3.40e-01 96.9% 26.6%
3399433 3826.1.1.39 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › WHEP-TRS 0.70 60.0 4.68e-01 100.0% 50.0%
3575095 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.69 58.0 4.73e-01 100.0% 52.3%
4952876 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 57.0 4.22e-01 100.0% 41.1%
3954762 3826.1.1.1 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Trns_repr_metal 0.68 57.0 4.28e-01 100.0% 40.5%
3928077 3636.1.1.0 a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain 0.68 57.0 3.76e-01 100.0% 23.4%
3932692 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.65 56.0 4.10e-01 100.0% 54.4%
3895470 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.63 50.0 3.79e-01 100.0% 36.8%
2098036 503.1.1.3 extended segments › N-terminal domain of bifunctional PutA protein › N-terminal domain of bifunctional PutA protein › N-terminal domain of bifunctional PutA protein › PutA_N 0.57 46.0 3.71e-01 100.0% 48.6%