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IMGVR_UViG_3300002460_002190-3300002460-C687J35021_100117488

Arc-Vir

IMGVR_UViG_3300002460_002190-3300002460-C687J35021_100117488

Quality

95.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-13_85-119_190-249
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF02511.21 best Thy1 50.2 3.70e-13 44.3% 19.9%
PF02511.21 Thy1 47.3 2.80e-12 43.4% 24.1%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2af6A01 3.30.70.3180 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.97 95.0 8.64e-01 100.0% 96.9%
2cfaA01 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.89 77.0 6.80e-01 89.6% 99.3%
3ah5B00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.89 81.0 6.27e-01 95.3% 100.0%
1kq4A00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.86 81.0 6.28e-01 97.2% 97.0%
5lt5A02 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.60 42.0 4.26e-01 70.8% 94.1%
1o51A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 43.0 4.60e-01 73.6% 93.3%
5w2fA01 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.59 43.0 4.67e-01 76.4% 100.0%
3devA02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.58 37.0 3.67e-01 70.8% 58.6%
3cgiA00 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.58 45.0 4.51e-01 85.8% 93.8%
1rf6A01 3.65.10.10 Alpha Beta › Alpha-beta prism › UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain › Enolpyruvate transferase domain 0.56 49.0 3.96e-01 100.0% 64.5%
2ab5A02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.55 46.0 4.36e-01 96.2% 79.9%
4c2mA09 3.30.70.2850 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 37.0 3.23e-01 70.8% 95.4%
3bguA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 38.0 3.97e-01 72.6% 97.9%
2dgxA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.54 37.0 4.11e-01 70.8% 100.0%
4l3tA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.53 43.0 3.33e-01 90.6% 84.5%
2ghpA03 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.53 38.0 4.16e-01 74.5% 97.6%
2qmwA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.53 37.0 4.22e-01 72.6% 100.0%
3i24B00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.53 38.0 3.52e-01 75.5% 100.0%
5ejrA01 1.25.40.530 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain 0.53 46.0 3.77e-01 96.2% 99.5%
5flmA02 3.30.1360.140 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.53 37.0 3.49e-01 73.6% 86.8%
2cpxA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.53 37.0 4.10e-01 72.6% 100.0%
3ko2A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.52 41.0 3.69e-01 87.7% 61.5%
3a7rA02 3.30.390.50 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain 0.52 37.0 3.97e-01 81.1% 88.8%
3au4A01 1.25.40.530 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain 0.52 46.0 3.81e-01 100.0% 98.5%
1j27A00 3.30.70.1120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TT1725-like 0.52 37.0 3.80e-01 74.5% 90.8%
2ex5A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.52 41.0 3.39e-01 87.7% 51.2%
3e54A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.52 40.0 3.63e-01 86.8% 64.2%
1vqzA02 3.30.390.50 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain 0.52 35.0 3.79e-01 78.3% 84.1%
4dzrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 42.0 3.68e-01 89.6% 81.0%
3icsA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.50 40.0 3.06e-01 86.8% 45.0%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
134624 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.97 95.0 6.88e-01 100.0% 98.0%
4977743 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.95 87.0 6.90e-01 93.4% 97.8%
4930760 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.95 87.0 6.21e-01 94.3% 87.3%
4152367 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.94 90.0 6.12e-01 98.1% 99.0%
4134497 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.94 86.0 6.40e-01 94.3% 94.3%
5077404 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.93 88.0 6.41e-01 97.2% 99.6%
4246528 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.93 88.0 6.43e-01 98.1% 100.0%
5001652 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.93 86.0 6.18e-01 96.2% 88.1%
4102574 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.92 86.0 6.27e-01 96.2% 100.0%
4988219 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.92 81.0 5.88e-01 91.5% 99.6%
5046119 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.92 83.0 6.41e-01 94.3% 100.0%
4943595 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.91 89.0 6.62e-01 100.0% 92.0%
4992830 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.91 85.0 6.36e-01 96.2% 88.0%
1007250 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.91 79.0 6.15e-01 89.6% 100.0%
4133204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 84.0 6.20e-01 97.2% 98.8%
5029299 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 79.0 6.10e-01 91.5% 98.1%
5024487 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 80.0 6.13e-01 92.5% 100.0%
4926808 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 80.0 6.03e-01 92.5% 95.5%
5066566 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 83.0 6.31e-01 97.2% 99.5%
4345249 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 79.0 5.93e-01 92.5% 92.0%
143031 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 82.0 6.32e-01 96.2% 100.0%
4982008 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.88 84.0 6.56e-01 99.1% 97.5%
4300356 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.88 81.0 6.26e-01 94.3% 100.0%
4628182 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 83.0 6.01e-01 99.1% 86.7%
4060791 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 82.0 5.96e-01 99.1% 86.3%
4941740 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.86 80.0 4.99e-01 97.2% 43.9%
4292511 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.86 79.0 4.92e-01 96.2% 52.8%
4264204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.86 79.0 5.61e-01 96.2% 93.1%
4933142 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 79.0 5.93e-01 100.0% 99.1%
5069296 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 77.0 5.61e-01 98.1% 79.2%
5018373 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.77 71.0 5.48e-01 97.2% 99.1%
3375878 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.65 42.0 4.89e-01 70.8% 94.7%
4394754 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.62 40.0 4.32e-01 74.5% 77.8%
3411100 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 42.0 2.77e-01 72.6% 32.9%
4169637 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.59 41.0 3.14e-01 71.7% 50.2%
3633871 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 46.0 3.75e-01 87.7% 83.3%
3468140 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.58 40.0 4.32e-01 71.7% 88.9%
4512382 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.56 40.0 3.92e-01 74.5% 78.3%
4230502 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.55 39.0 3.80e-01 73.6% 95.0%
3604277 327.11.2.82 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF27275 0.55 35.0 4.07e-01 88.7% 92.0%
3677440 862.1.1.11 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › AEP_C962R 0.55 42.0 3.26e-01 82.1% 76.3%
4042212 304.11.1.0 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.55 39.0 3.76e-01 74.5% 97.6%
3760983 3335.1.1.3 beta barrels › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B › Handle domain in transferrin-binding protein B › KCTD18_C 0.54 31.0 3.26e-01 86.8% 59.0%
3895696 304.151.1.5 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › JAG1 0.54 39.0 3.91e-01 77.4% 100.0%
3503198 3914.1.1.2 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer 0.53 44.0 2.87e-01 90.6% 81.0%
3844481 11.1.1.640 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N 0.53 41.0 4.08e-01 82.1% 89.1%
3500307 306.3.1.0 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.53 43.0 4.21e-01 91.5% 80.9%
4945049 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.53 36.0 3.79e-01 74.5% 78.9%
4960640 304.165.1.4 a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 › HVO_2525_N 0.53 45.0 4.08e-01 93.4% 77.9%
4962490 244.2.1.1 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim 0.53 41.0 3.92e-01 84.0% 91.2%
3742562 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 43.0 4.19e-01 87.7% 81.7%
4965026 304.165.1.2 a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 › BAT 0.53 44.0 3.98e-01 92.5% 74.7%
3249652 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.52 41.0 3.86e-01 86.8% 68.9%
5061124 244.2.1.1 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim 0.52 42.0 3.98e-01 88.7% 91.5%
4997121 101.1.2.136 alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.52 32.0 2.68e-01 92.5% 34.2%
4961458 304.165.1.0 a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 0.51 44.0 3.91e-01 93.4% 82.0%
3725795 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.51 41.0 3.87e-01 88.7% 96.9%
4961281 304.165.1.2 a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 › BAT 0.50 43.0 3.83e-01 93.4% 77.3%
D2 high residues 17-82
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2nscA01 3.30.70.1050 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Trigger factor ribosome-binding domain 0.56 37.0 3.51e-01 80.3% 56.4%
1l8qA03 1.10.1750.10 Mainly Alpha › Orthogonal Bundle › Chromosomal Replication Initiator Protein Dnaa; Chain: A; › DnaA protein, C-terminal DNA-binding domain 0.52 38.0 3.35e-01 80.3% 96.3%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3167378 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.53 41.0 3.01e-01 83.3% 58.2%
3989118 7523.1.1.8 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_1 0.53 43.0 3.12e-01 92.4% 38.6%
3615392 2007.1.2.27 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_A-cyclase 0.51 40.0 2.86e-01 86.4% 61.9%
3639310 3924.1.1.1 alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Fungal_trans_2 0.51 42.0 3.03e-01 90.9% 90.0%
D3 high residues 132-184
PDB
Domain cluster: representative
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2j82A00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.87 66.0 4.24e-01 81.1% 20.4%
2h09A02 1.10.60.10 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Iron dependent repressor, metal binding and dimerisation domain 0.83 54.0 5.37e-01 96.2% 64.3%
4mk6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.81 70.0 4.68e-01 94.3% 66.5%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.80 58.0 5.37e-01 77.4% 62.7%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.79 63.0 4.54e-01 92.5% 31.9%
2xmoA02 1.10.246.180 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.78 59.0 4.99e-01 81.1% 55.8%
3iieB03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.76 52.0 4.39e-01 77.4% 44.7%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.75 63.0 6.00e-01 98.1% 78.7%
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.75 58.0 5.37e-01 84.9% 69.1%
4jndA01 1.10.1740.220 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.74 52.0 3.88e-01 73.6% 36.2%
4ye6A01 1.10.8.1290 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1 0.74 47.0 3.77e-01 75.5% 33.7%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.73 62.0 5.42e-01 94.3% 73.4%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.73 65.0 4.52e-01 98.1% 75.8%
2aplA01 1.10.8.330 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like 0.72 54.0 5.04e-01 83.0% 64.7%
3nyjA00 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.72 64.0 4.36e-01 98.1% 35.4%
2f2cA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.71 50.0 4.01e-01 75.5% 43.4%
3umgA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.71 52.0 4.79e-01 84.9% 60.6%
1qdmA03 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.70 49.0 4.35e-01 73.6% 51.9%
1tfeA02 1.10.286.20 Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › 0.70 49.0 5.21e-01 77.4% 93.3%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 58.0 4.72e-01 94.3% 67.6%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 58.0 4.59e-01 92.5% 46.2%
4k08A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.69 58.0 4.29e-01 96.2% 36.1%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 52.0 4.16e-01 94.3% 42.6%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 58.0 5.27e-01 92.5% 74.6%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.69 60.0 3.70e-01 98.1% 53.5%
3b0bC02 6.10.130.30 Special › Helix non-globular › GTP Cyclohydrolase I; Chain A, domain 1 › 0.68 46.0 5.01e-01 79.2% 88.4%
3j27B00 1.10.8.970 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Flavivirus envelope glycoprotein M-like 0.67 47.0 4.29e-01 75.5% 58.3%
3t69A02 3.30.420.310 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain 0.67 57.0 3.72e-01 96.2% 73.0%
4dhxB00 1.10.246.140 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › ENY2/SUS1 0.66 51.0 4.24e-01 88.7% 48.4%
2x4hA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 59.0 4.41e-01 100.0% 62.0%
3b0cW00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.66 56.0 5.12e-01 100.0% 72.6%
1kyoF00 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.66 46.0 4.11e-01 86.8% 52.7%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.65 56.0 4.03e-01 100.0% 48.8%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.65 51.0 4.95e-01 94.3% 77.4%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.65 47.0 4.15e-01 84.9% 52.7%
3o60A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 53.0 3.66e-01 92.5% 65.4%
3fd0A01 3.90.1150.60 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Methioning gamme-lyase, C-terminal domain 0.64 52.0 3.65e-01 96.2% 68.4%
4a55A01 3.10.20.770 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.64 52.0 3.19e-01 90.6% 31.6%
3dfzA02 1.10.8.610 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › SirC, precorrin-2 dehydrogenase, C-terminal helical domain-like 0.63 47.0 4.28e-01 81.1% 60.8%
3c1dA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 41.0 4.29e-01 73.6% 80.4%
3keyA01 1.10.10.1080 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain 0.60 46.0 3.97e-01 84.9% 59.8%
3c8tA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.60 47.0 3.85e-01 84.9% 73.2%
1jkwA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.59 43.0 3.62e-01 81.1% 42.6%
1t33A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 46.0 3.33e-01 88.7% 72.8%
3cbuA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 49.0 3.68e-01 96.2% 41.8%
2lrmA00 1.10.890.30 Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › YmgD protein 0.58 42.0 3.68e-01 79.2% 51.2%
7nc3F01 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 50.0 3.85e-01 96.2% 44.7%
3qnmA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.57 40.0 3.60e-01 83.0% 51.1%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3398929 5041.1.1.32 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM141 0.91 84.0 6.91e-01 100.0% 73.3%
5026378 3542.1.1.2 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › SPP 0.90 78.0 4.85e-01 94.3% 19.6%
3486587 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.88 78.0 4.80e-01 100.0% 18.2%
3394799 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.88 80.0 4.91e-01 100.0% 32.6%
4191254 1023.1.1.1 beta barrels › Cell division protein ZapC N-terminal domain › Cell division protein ZapC N-terminal domain › Cell division protein ZapC N-terminal domain › ZapC_N 0.87 63.0 5.12e-01 75.5% 44.4%
4246528 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.86 78.0 4.95e-01 100.0% 21.7%
5066085 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.86 71.0 5.77e-01 90.6% 51.6%
3741742 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.85 77.0 4.83e-01 100.0% 31.3%
4031352 6026.1.1.43 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › DUF1024 0.85 73.0 6.28e-01 96.2% 66.7%
3821344 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.85 76.0 4.61e-01 100.0% 29.5%
3926907 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.85 77.0 4.74e-01 100.0% 31.9%
3261624 3470.1.1.0 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain 0.84 61.0 6.32e-01 79.2% 86.0%
3482541 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.83 74.0 4.63e-01 100.0% 33.3%
4971098 140.1.1.0 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.83 58.0 3.88e-01 73.6% 20.7%
3721541 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.83 69.0 5.50e-01 90.6% 48.0%
3275619 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.82 72.0 5.30e-01 98.1% 39.3%
4663888 5069.1.3.126 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › PLDc_N 0.82 60.0 5.25e-01 79.2% 53.8%
4031085 3826.1.1.79 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › DUF1024 0.81 70.0 6.22e-01 98.1% 73.1%
3925650 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.81 72.0 4.46e-01 100.0% 32.3%
3715420 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.81 71.0 5.51e-01 98.1% 51.3%
3231906 397.7.1.4 few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 › C_tripleX 0.81 55.0 5.95e-01 71.7% 84.4%
3453796 7519.1.1.11 a/b three-layered sandwiches › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › Rick_17kDa_Anti, PF29034 0.81 71.0 5.68e-01 100.0% 56.2%
3649222 2004.1.1.23 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.80 68.0 4.10e-01 98.1% 15.5%
4936252 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.79 69.0 5.69e-01 98.1% 58.9%
3570117 375.6.1.2 few secondary structure elements › Rubredoxin-like › FlhC-like › FlhC-like › PF31275 0.79 65.0 6.25e-01 96.2% 80.0%
3218921 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.79 70.0 5.48e-01 98.1% 56.9%
3516948 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.78 69.0 4.29e-01 100.0% 18.9%
3798232 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.78 68.0 5.73e-01 98.1% 58.0%
3590532 1075.1.2.13 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › CNNM 0.77 64.0 4.61e-01 98.1% 33.9%
3222805 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.76 66.0 4.15e-01 98.1% 18.9%
4023307 183.1.1.0 alpha duplicates or obligate multimers › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain 0.75 58.0 5.14e-01 90.6% 58.7%
3639658 1072.1.1.1 alpha bundles › Hsp90 co-chaperone Cdc37 N-terminal domain › Hsp90 co-chaperone Cdc37 N-terminal domain › Hsp90 co-chaperone Cdc37 N-terminal domain › CDC37_N 0.75 64.0 4.50e-01 96.2% 33.9%
4944477 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.75 64.0 4.42e-01 98.1% 29.7%
3331094 148.1.1.15 alpha arrays › Histone-like › Histone-related › Histone › CENP-X 0.74 62.0 4.99e-01 100.0% 49.5%
4964216 5063.1.1.24 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › PF26047 0.73 52.0 4.99e-01 79.2% 66.2%
3451236 397.4.1.3 few secondary structure elements › Toxic hairpin › VhTI-like › VhTI-like › PF31266 0.72 48.0 5.17e-01 77.4% 82.2%
4198250 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.72 52.0 4.76e-01 83.0% 58.6%
2986104 3226.1.1.3 alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp 0.72 56.0 3.40e-01 83.0% 37.7%
3344802 6158.1.1.0 alpha bundles › Nucleoporin p58/p45 helical region › Nucleoporin p58/p45 helical region › Nucleoporin p58/p45 helical region 0.72 58.0 5.52e-01 94.3% 76.9%
5039558 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 56.0 4.20e-01 86.8% 34.8%
3598977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 59.0 5.14e-01 98.1% 60.0%
4998530 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.71 61.0 3.80e-01 92.5% 18.9%
3167091 148.1.1.12 alpha arrays › Histone-like › Histone-related › Histone › Bromo_TP 0.70 60.0 5.10e-01 100.0% 57.8%
3252688 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.70 58.0 4.08e-01 94.3% 29.7%
3408508 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.69 55.0 4.85e-01 88.7% 58.7%
3741613 101.1.2.73 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82 0.69 62.0 4.39e-01 98.1% 74.0%
2859100 148.1.1.0 alpha arrays › Histone-like › Histone-related › Histone 0.68 61.0 5.46e-01 100.0% 85.1%
5036957 3542.1.1.2 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › SPP 0.67 54.0 3.41e-01 88.7% 67.8%
3514607 3226.1.1.3 alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp 0.67 56.0 3.51e-01 98.1% 21.3%
3285078 191.1.1.63 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_N 0.66 57.0 3.88e-01 100.0% 38.5%
3608485 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.65 54.0 4.17e-01 90.6% 41.7%
3617842 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.58 47.0 4.17e-01 92.5% 75.0%
3991663 4336.2.1.1 alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 › EnY2 0.55 49.0 4.04e-01 100.0% 86.3%