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IMGVR_UViG_3300002460_002959-3300002460-C687J35021_100112852
Arc-VirIMGVR_UViG_3300002460_002959-3300002460-C687J35021_100112852
Identity
- Kingdom:
- archaea
Quality
69.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 453-556
Domain cluster:
rep: IMGVR_UViG_3300035037_000444-3300035037-Ga0376511_006805_2915_4249__D131-208
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1z5bB03 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.63 | 55.0 | 4.96e-01 | 100.0% | 91.9% |
| 1nz0D00 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.61 | 51.0 | 5.00e-01 | 96.2% | 83.8% |
| 1a6fA00 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.60 | 49.0 | 4.77e-01 | 97.1% | 80.5% |
| 6n0xF01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.59 | 51.0 | 4.31e-01 | 95.2% | 67.8% |
| 6q3wD01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.56 | 48.0 | 3.97e-01 | 95.2% | 65.2% |
| 1ac5A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.54 | 47.0 | 3.07e-01 | 97.1% | 28.6% |
| 4rzkA00 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.52 | 31.0 | 3.38e-01 | 92.3% | 70.1% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4860816 | 212.1.1.10 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › RNase_PH | 0.63 | 55.0 | 5.09e-01 | 97.1% | 91.1% |
| 3968852 | 212.1.1.1 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › HSP90 | 0.63 | 57.0 | 5.06e-01 | 100.0% | 74.7% |
| 3281176 | 2003.1.2.113 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Smoa_sbd | 0.54 | 38.0 | 2.56e-01 | 93.3% | 19.5% |
| 4974098 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.52 | 34.0 | 3.60e-01 | 94.2% | 76.7% |
| 4491860 | 221.15.1.0 ↗ | a+b two layers › beta-Grasp › beta-grasp fold domain in leucine-tRNA ligase › beta-grasp fold domain in leucine-tRNA ligase | 0.51 | 27.0 | 3.24e-01 | 93.3% | 81.0% |
| 169505 | 319.1.1.7 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › SHQ1-like_CS | 0.50 | 33.0 | 3.41e-01 | 93.3% | 69.7% |
D2
medium
residues 255-267_300-388
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6m9yA00 | 3.30.1300.40 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.69 | 32.0 | 4.02e-01 | 94.1% | 73.7% |
| 6gp1A00 | 3.30.1300.40 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.68 | 35.0 | 4.22e-01 | 96.1% | 75.4% |
| 6hmjA01 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.60 | 39.0 | 3.91e-01 | 82.4% | 63.8% |
| 6rh8A02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.60 | 45.0 | 3.91e-01 | 79.4% | 69.0% |
| 3icyA00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.59 | 39.0 | 3.69e-01 | 80.4% | 57.6% |
| 4iedA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.56 | 43.0 | 3.37e-01 | 85.3% | 75.6% |
| 2ebkA00 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.55 | 40.0 | 3.73e-01 | 95.1% | 60.2% |
| 1b7yB05 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.55 | 45.0 | 3.61e-01 | 87.3% | 89.0% |
| 4jhyA00 | 3.30.530.80 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › | 0.53 | 38.0 | 3.27e-01 | 72.5% | 51.3% |
| 3ednA02 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.53 | 39.0 | 3.34e-01 | 81.4% | 48.2% |
| 3mqqB00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.53 | 36.0 | 3.51e-01 | 82.4% | 60.2% |
| 1gydB00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.53 | 41.0 | 2.99e-01 | 85.3% | 93.3% |
| 2ebmA00 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.52 | 35.0 | 3.27e-01 | 94.1% | 53.9% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3376998 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.76 | 70.0 | 4.94e-01 | 100.0% | 61.4% |
| 3266323 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.67 | 37.0 | 3.51e-01 | 92.2% | 44.2% |
| 3789933 | 11.10.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like | 0.60 | 35.0 | 3.53e-01 | 80.4% | 56.2% |
| 3200639 | 642.1.1.0 ↗ | a+b three layers › Suppressor of Fused, N-terminal domain › Suppressor of Fused, N-terminal domain › Suppressor of Fused, N-terminal domain | 0.57 | 35.0 | 2.84e-01 | 90.2% | 32.6% |
| 3214289 | 214.1.1.1 ↗ | a+b two layers › SH2 › SH2 › SH2 › SH2 | 0.57 | 37.0 | 3.62e-01 | 88.2% | 59.1% |
| 3998660 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.56 | 29.0 | 3.14e-01 | 94.1% | 56.7% |
| 3788566 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.56 | 36.0 | 3.17e-01 | 95.1% | 44.7% |
| 165196 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.55 | 40.0 | 3.73e-01 | 95.1% | 60.2% |
| 3176181 | 4252.1.1.5 ↗ | beta barrels › AttH-like › AttH-like › AttH-like › Svf1 | 0.55 | 38.0 | 3.02e-01 | 70.6% | 49.3% |
| 3250157 | 7504.1.1.2 ↗ | a/b three-layered sandwiches › ITPase-like › ITPase-like › ITPase-like › NTPase_I-T | 0.54 | 47.0 | 3.85e-01 | 94.1% | 64.3% |
| 3591533 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.54 | 40.0 | 3.37e-01 | 76.5% | 51.8% |
| 4023469 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.53 | 36.0 | 3.25e-01 | 96.1% | 50.0% |
| 3195333 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.53 | 41.0 | 3.74e-01 | 81.4% | 72.6% |
| 4514345 | 274.1.1.50 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits › Spore_YunB | 0.53 | 40.0 | 3.56e-01 | 79.4% | 85.5% |
| 5001466 | 2484.1.1.59 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA | 0.53 | 45.0 | 3.20e-01 | 95.1% | 78.2% |
| 4366861 | 314.1.1.11 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA_synthFbeta | 0.53 | 41.0 | 3.22e-01 | 83.3% | 78.2% |
| 3482965 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.52 | 37.0 | 3.47e-01 | 74.5% | 63.1% |
| 5067760 | 283.1.1.0 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase | 0.51 | 32.0 | 3.42e-01 | 80.4% | 71.1% |
| 3237854 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.51 | 33.0 | 3.23e-01 | 74.5% | 58.3% |
D3
medium
residues 268-299_389-450
Domain cluster:
representative
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1y4uB01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.72 | 64.0 | 4.98e-01 | 95.7% | 87.6% |
| 2o1uB01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.71 | 62.0 | 5.08e-01 | 93.6% | 93.9% |
| 1pvgA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.71 | 66.0 | 4.73e-01 | 98.9% | 73.4% |
| 1e8oA00 | 3.30.720.10 | Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 | 0.66 | 43.0 | 4.74e-01 | 98.9% | 83.8% |
| 1txdA02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.64 | 40.0 | 3.67e-01 | 98.9% | 47.9% |
| 7r8iA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.63 | 48.0 | 3.73e-01 | 83.0% | 80.2% |
| 5zi7A01 | 2.60.40.1730 | Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain | 0.60 | 52.0 | 4.15e-01 | 95.7% | 93.0% |
| 3n4pC00 | 3.30.420.320 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › DNA-packaging terminase, C-terminal nuclease domain | 0.60 | 49.0 | 3.83e-01 | 92.6% | 93.6% |
| 3eniC00 | 2.50.10.10 | Mainly Beta › Clam › Bacteriochlorophyll-a Protein › Bacteriochlorophyll A | 0.60 | 47.0 | 3.24e-01 | 87.2% | 96.6% |
| 3qnfC01 | 2.60.40.1730 | Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain | 0.59 | 50.0 | 3.96e-01 | 95.7% | 91.2% |
| 3hrgA01 | 3.30.420.250 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Protein of unknown function DUF3822, N-terminal domain | 0.59 | 50.0 | 4.35e-01 | 93.6% | 94.4% |
| 6d92A01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.59 | 46.0 | 3.48e-01 | 86.2% | 79.9% |
| 4kx7A01 | 2.60.40.1730 | Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain | 0.58 | 50.0 | 3.84e-01 | 95.7% | 87.2% |
| 4c23B01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.58 | 48.0 | 3.66e-01 | 92.6% | 96.6% |
| 2xq0A01 | 2.60.40.1730 | Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain | 0.57 | 49.0 | 3.96e-01 | 94.7% | 94.4% |
| 4gaaA01 | 2.60.40.1730 | Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain | 0.56 | 49.0 | 3.87e-01 | 95.7% | 92.7% |
| 3agkA02 | 3.30.420.60 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 | 0.56 | 44.0 | 4.04e-01 | 85.1% | 78.2% |
| 3cerC01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.56 | 43.0 | 3.98e-01 | 85.1% | 85.2% |
| 1t6cA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.56 | 43.0 | 3.97e-01 | 84.0% | 84.8% |
| 1hkgA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.56 | 42.0 | 3.87e-01 | 81.9% | 95.4% |
| 3cqyB01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.56 | 45.0 | 3.68e-01 | 90.4% | 100.0% |
| 3d3rA00 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.55 | 27.0 | 2.88e-01 | 93.6% | 49.4% |
| 1z5hA01 | 2.60.40.1730 | Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain | 0.55 | 48.0 | 3.95e-01 | 95.7% | 93.5% |
| 1okjB01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.55 | 45.0 | 4.07e-01 | 89.4% | 93.7% |
| 3wxmB02 | 3.30.420.60 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 | 0.54 | 44.0 | 4.12e-01 | 90.4% | 73.8% |
| 1xc3A01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 42.0 | 4.13e-01 | 85.1% | 94.2% |
| 4axhA03 | 3.30.1050.10 | Alpha Beta › 2-Layer Sandwich › Nonspecific Lipid-transfer Protein; Chain A › SCP2 sterol-binding domain | 0.54 | 40.0 | 3.64e-01 | 87.2% | 57.0% |
| 1e3mB02 | 3.30.420.110 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › MutS, connector domain | 0.54 | 37.0 | 3.38e-01 | 88.3% | 51.1% |
| 3ciaA01 | 2.60.40.1730 | Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain | 0.54 | 45.0 | 3.68e-01 | 94.7% | 94.0% |
| 4nurA03 | 3.30.1050.10 | Alpha Beta › 2-Layer Sandwich › Nonspecific Lipid-transfer Protein; Chain A › SCP2 sterol-binding domain | 0.53 | 40.0 | 3.60e-01 | 88.3% | 56.5% |
| 3lm2A01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.53 | 42.0 | 4.21e-01 | 86.2% | 93.8% |
| 4gniA03 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.53 | 41.0 | 4.28e-01 | 85.1% | 96.6% |
| 2a6aB01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.53 | 41.0 | 3.86e-01 | 84.0% | 95.8% |
| 3bexA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.53 | 42.0 | 3.73e-01 | 86.2% | 98.5% |
| 1of5A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 38.0 | 3.21e-01 | 90.4% | 46.1% |
| 3hrgA02 | 3.30.420.260 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Protein of unknown function DUF3822, C-terminal domain | 0.52 | 41.0 | 3.84e-01 | 83.0% | 71.9% |
| 2cfuA03 | 3.30.1050.10 | Alpha Beta › 2-Layer Sandwich › Nonspecific Lipid-transfer Protein; Chain A › SCP2 sterol-binding domain | 0.52 | 38.0 | 3.46e-01 | 86.2% | 56.6% |
| 1pzxA03 | 3.30.1180.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › | 0.52 | 40.0 | 3.78e-01 | 87.2% | 99.2% |
| 5eoxB03 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.51 | 41.0 | 3.76e-01 | 88.3% | 96.9% |
| 1wn9A00 | 3.40.1530.10 | Alpha Beta › 3-Layer(aba) Sandwich › hypothetical protein tt1805 › TTHA1528-like | 0.51 | 42.0 | 3.87e-01 | 93.6% | 83.3% |
| 1atrA03 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.51 | 39.0 | 4.01e-01 | 85.1% | 92.1% |
| 2qi2A02 | 3.30.420.60 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 | 0.50 | 39.0 | 3.70e-01 | 84.0% | 75.4% |
| 3kksB00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.50 | 39.0 | 3.37e-01 | 90.4% | 52.0% |
| 3mcpA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.50 | 40.0 | 3.81e-01 | 88.3% | 93.8% |
ECOD (82)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5027857 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.78 | 71.0 | 5.22e-01 | 97.9% | 83.6% |
| None | — | 0.75 | 66.0 | 4.98e-01 | 93.6% | 89.4% | |
| 4076203 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.74 | 67.0 | 4.81e-01 | 96.8% | 85.6% |
| 3902919 | 225.1.1.2 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HSP90,HATPase_c_3 | 0.72 | 65.0 | 4.68e-01 | 96.8% | 76.3% |
| 4504528 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.71 | 60.0 | 4.38e-01 | 90.4% | 82.9% |
| 3974412 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.68 | 62.0 | 4.73e-01 | 97.9% | 83.9% |
| 5032371 | 896.1.1.0 ↗ | a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related | 0.68 | 42.0 | 4.81e-01 | 74.5% | 84.3% |
| 3213706 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.65 | 48.0 | 3.65e-01 | 78.7% | 48.2% |
| 2814146 | 896.1.1.1 ↗ | a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Ribosomal_L38e | 0.64 | 42.0 | 4.56e-01 | 89.4% | 82.9% |
| 3693331 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.62 | 50.0 | 3.91e-01 | 88.3% | 86.5% |
| 5063745 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.62 | 53.0 | 4.12e-01 | 92.6% | 92.5% |
| 4411984 | 2484.1.1.114 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Med13_C | 0.61 | 51.0 | 4.15e-01 | 91.5% | 100.0% |
| 3385434 | 2484.1.1.261 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27038 | 0.61 | 48.0 | 4.23e-01 | 85.1% | 86.4% |
| 4156379 | 2484.1.1.41 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › AnmK | 0.61 | 50.0 | 4.19e-01 | 90.4% | 100.0% |
| 3222823 | 4081.1.1.5 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N | 0.59 | 51.0 | 4.01e-01 | 94.7% | 95.0% |
| 3174283 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.59 | 51.0 | 3.68e-01 | 94.7% | 96.6% |
| 3933456 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.59 | 40.0 | 4.13e-01 | 70.2% | 100.0% |
| 4022865 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 48.0 | 3.65e-01 | 89.4% | 76.8% |
| 4948545 | 4081.1.1.5 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N | 0.59 | 51.0 | 4.05e-01 | 94.7% | 94.2% |
| 3700987 | 4081.1.1.5 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N | 0.59 | 50.0 | 3.98e-01 | 94.7% | 93.0% |
| 3598670 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.59 | 50.0 | 3.97e-01 | 94.7% | 94.0% |
| 5023939 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.59 | 47.0 | 4.49e-01 | 92.6% | 74.5% |
| 3957099 | 268.1.1.4 ↗ | a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related › Alkyl_sulf_C | 0.59 | 43.0 | 3.99e-01 | 89.4% | 61.7% |
| 3491854 | 4081.1.1.5 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N | 0.59 | 50.0 | 3.98e-01 | 94.7% | 91.3% |
| 3733008 | 2484.1.1.114 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Med13_C | 0.58 | 49.0 | 3.44e-01 | 92.6% | 56.2% |
| 1144831 | 2484.1.1.63 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF3822 | 0.58 | 50.0 | 4.25e-01 | 95.7% | 87.2% |
| 3860841 | 4081.1.1.5 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N | 0.58 | 50.0 | 3.80e-01 | 96.8% | 93.9% |
| 4144852 | 220.1.1.126 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Ycf4 | 0.58 | 42.0 | 4.02e-01 | 76.6% | 84.3% |
| 5052285 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.57 | 45.0 | 4.43e-01 | 88.3% | 77.1% |
| 3980648 | 4091.1.1.1 ↗ | beta complex topology › L,D-transpeptidase catalytic domain-like › L,D-transpeptidase catalytic domain-like › L,D-transpeptidase catalytic domain-like › YkuD | 0.57 | 48.0 | 3.85e-01 | 92.6% | 92.2% |
| 3953220 | 2484.1.1.216 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF7159 | 0.57 | 44.0 | 4.09e-01 | 81.9% | 69.7% |
| 3978292 | 2484.1.1.251 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF26691 | 0.57 | 49.0 | 3.33e-01 | 98.9% | 32.7% |
| 2722109 | 4091.1.1.1 ↗ | beta complex topology › L,D-transpeptidase catalytic domain-like › L,D-transpeptidase catalytic domain-like › L,D-transpeptidase catalytic domain-like › YkuD | 0.57 | 39.0 | 3.24e-01 | 71.3% | 82.8% |
| 3961936 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 43.0 | 3.90e-01 | 78.7% | 60.8% |
| 2323940 | 2484.8.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) › Peptidase_C50 | 0.57 | 44.0 | 3.14e-01 | 83.0% | 86.4% |
| 3635379 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 46.0 | 3.74e-01 | 91.5% | 90.3% |
| 4200322 | 2484.1.1.114 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Med13_C | 0.57 | 46.0 | 3.29e-01 | 90.4% | 67.0% |
| 3653902 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.56 | 42.0 | 3.29e-01 | 80.9% | 82.8% |
| 3641026 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.56 | 47.0 | 3.83e-01 | 92.6% | 93.9% |
| 3785219 | 2484.1.1.114 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Med13_C | 0.56 | 45.0 | 3.32e-01 | 90.4% | 67.5% |
| 3439369 | 11.1.1.837 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › TAF2_3rd | 0.56 | 44.0 | 3.35e-01 | 85.1% | 68.7% |
| 5071337 | 2484.1.1.49 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N | 0.55 | 44.0 | 4.25e-01 | 85.1% | 92.4% |
| 3788773 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.55 | 47.0 | 3.44e-01 | 94.7% | 92.8% |
| 3952658 | 2484.1.1.113 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › baeRF_family2 | 0.55 | 44.0 | 3.99e-01 | 85.1% | 84.0% |
| 3960090 | 2484.1.1.216 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF7159 | 0.55 | 42.0 | 3.42e-01 | 84.0% | 41.0% |
| 4378051 | 2484.1.1.10 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › TsaD | 0.55 | 43.0 | 4.02e-01 | 85.1% | 96.7% |
| 3595343 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.55 | 46.0 | 3.66e-01 | 94.7% | 88.8% |
| 5078594 | 2484.1.1.38 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 | 0.55 | 44.0 | 3.99e-01 | 88.3% | 77.7% |
| 5053605 | 268.1.1.0 ↗ | a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related | 0.55 | 44.0 | 4.08e-01 | 88.3% | 69.4% |
| 5057683 | 2484.1.1.38 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 | 0.55 | 42.0 | 3.87e-01 | 84.0% | 77.6% |
| 3698924 | 4081.1.1.5 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N | 0.54 | 46.0 | 3.67e-01 | 96.8% | 89.8% |
| 3213262 | 145.1.1.0 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain | 0.54 | 40.0 | 3.92e-01 | 75.5% | 86.0% |
| 5079400 | 268.1.1.1 ↗ | a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related › SCP2 | 0.54 | 42.0 | 3.99e-01 | 88.3% | 70.4% |
| 4504545 | 2484.2.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Methylated DNA-protein cysteine methyltransferase domain › Methylated DNA-protein cysteine methyltransferase domain | 0.54 | 37.0 | 3.67e-01 | 71.3% | 66.0% |
| 3510204 | 10.1.1.17 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 | 0.54 | 48.0 | 3.19e-01 | 100.0% | 30.8% |
| 3706768 | 3407.1.1.0 ↗ | mixed a+b and a/b › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain | 0.54 | 43.0 | 3.83e-01 | 86.2% | 66.7% |
| 3178498 | 2484.1.1.57 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ydc2-catalyt | 0.54 | 44.0 | 3.17e-01 | 90.4% | 44.1% |
| 5031007 | 2484.1.1.38 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 | 0.54 | 42.0 | 3.91e-01 | 87.2% | 77.6% |
| 3370453 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.54 | 41.0 | 3.23e-01 | 83.0% | 81.4% |
| 1144832 | 2484.1.1.63 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF3822 | 0.54 | 41.0 | 4.11e-01 | 83.0% | 82.0% |
| 5043655 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.53 | 41.0 | 3.60e-01 | 81.9% | 91.4% |
| 3966660 | 268.1.1.0 ↗ | a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related | 0.53 | 39.0 | 3.44e-01 | 86.2% | 53.3% |
| 3653703 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.53 | 43.0 | 3.45e-01 | 91.5% | 87.3% |
| 4600425 | 2484.1.1.40 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX | 0.53 | 41.0 | 3.60e-01 | 86.2% | 58.7% |
| 5036730 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.53 | 43.0 | 4.02e-01 | 90.4% | 78.3% |
| 3646441 | 2484.1.1.205 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27035 | 0.53 | 41.0 | 3.93e-01 | 88.3% | 71.8% |
| 4123278 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.53 | 42.0 | 3.54e-01 | 89.4% | 57.6% |
| 4118739 | 2484.1.1.40 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX | 0.53 | 41.0 | 3.61e-01 | 85.1% | 62.1% |
| 4367636 | 2484.1.1.48 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II | 0.53 | 42.0 | 3.59e-01 | 88.3% | 53.9% |
| 4171807 | 2484.1.1.40 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX | 0.53 | 41.0 | 3.52e-01 | 86.2% | 57.5% |
| 4071071 | 2484.1.1.40 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX | 0.52 | 41.0 | 3.56e-01 | 85.1% | 59.3% |
| 4376375 | 2484.1.1.49 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N | 0.52 | 41.0 | 3.62e-01 | 86.2% | 70.3% |
| 3258353 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.52 | 41.0 | 3.19e-01 | 83.0% | 88.5% |
| 3653704 | 2498.1.1.91 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › TAF2_3rd | 0.52 | 41.0 | 3.02e-01 | 85.1% | 46.2% |
| 4365245 | 2484.1.1.174 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH | 0.52 | 42.0 | 3.84e-01 | 88.3% | 70.4% |
| 3402776 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.52 | 41.0 | 3.22e-01 | 86.2% | 81.4% |
| 3838417 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.51 | 39.0 | 3.57e-01 | 84.0% | 60.0% |
| 4468760 | 2484.1.1.153 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1744 | 0.51 | 40.0 | 2.85e-01 | 87.2% | 35.6% |
| 3278880 | 268.1.1.1 ↗ | a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related › SCP2 | 0.51 | 39.0 | 3.57e-01 | 87.2% | 62.5% |
| 3924099 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.51 | 44.0 | 3.38e-01 | 97.9% | 58.7% |
| 4134120 | 2484.1.1.48 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II | 0.51 | 41.0 | 3.45e-01 | 87.2% | 53.8% |
| 3173778 | 268.1.1.4 ↗ | a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related › Alkyl_sulf_C | 0.51 | 37.0 | 3.40e-01 | 87.2% | 57.6% |
D4
medium
residues 557-664_733-749
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6rqxA02 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.60 | 41.0 | 3.29e-01 | 82.4% | 35.0% |
| 4kx7A02 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.58 | 41.0 | 3.27e-01 | 82.4% | 35.7% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3782282 | 2498.1.1.36 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › WLM | 0.70 | 42.0 | 4.06e-01 | 76.8% | 52.9% |
| 4011118 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.57 | 43.0 | 3.39e-01 | 82.4% | 37.4% |
D5
medium
residues 665-732
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4dhxB00 | 1.10.246.140 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › ENY2/SUS1 | 0.65 | 42.0 | 3.88e-01 | 92.6% | 49.5% |
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.65 | 43.0 | 4.34e-01 | 83.8% | 68.7% |
| 1b10A00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.65 | 52.0 | 4.48e-01 | 100.0% | 56.7% |
| 3h5qA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.65 | 33.0 | 3.27e-01 | 70.6% | 48.6% |
| 2dsjA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.64 | 32.0 | 3.31e-01 | 70.6% | 50.7% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.63 | 43.0 | 3.82e-01 | 91.2% | 48.0% |
| 3d0wA00 | 1.10.760.20 | Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Protein of unknown function DUF3243 | 0.62 | 43.0 | 4.00e-01 | 75.0% | 57.0% |
| 3w04A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.61 | 44.0 | 2.99e-01 | 77.9% | 66.7% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.60 | 38.0 | 3.62e-01 | 98.5% | 53.1% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.60 | 43.0 | 3.20e-01 | 76.5% | 81.4% |
| 1gt0D00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.58 | 46.0 | 4.47e-01 | 100.0% | 81.0% |
| 4m70B00 | 1.10.246.200 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain | 0.58 | 42.0 | 3.87e-01 | 80.9% | 58.2% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 39.0 | 3.50e-01 | 70.6% | 46.6% |
| 5h8yD02 | 3.30.413.10 | Alpha Beta › 2-Layer Sandwich › Sulfite Reductase Hemoprotein; domain 1 › Sulfite Reductase Hemoprotein, domain 1 | 0.57 | 42.0 | 3.06e-01 | 79.4% | 82.8% |
| 2e62A01 | 6.10.140.420 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 39.0 | 4.25e-01 | 73.5% | 92.3% |
| 3ecsC01 | 1.20.120.1070 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain | 0.57 | 39.0 | 3.51e-01 | 95.6% | 48.0% |
| 1qrvA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.57 | 49.0 | 4.86e-01 | 100.0% | 94.5% |
| 4wqkA00 | 3.30.460.40 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › | 0.57 | 38.0 | 2.84e-01 | 70.6% | 86.9% |
| 3w0lD02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.56 | 47.0 | 3.09e-01 | 100.0% | 99.4% |
| 4m9aA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 38.0 | 3.20e-01 | 72.1% | 40.3% |
| 2ipcA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.55 | 46.0 | 3.26e-01 | 98.5% | 47.5% |
| 2ktmA00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.55 | 40.0 | 4.07e-01 | 88.2% | 80.9% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.55 | 39.0 | 2.85e-01 | 75.0% | 64.8% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 41.0 | 3.23e-01 | 80.9% | 76.4% |
| 2c12A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.54 | 36.0 | 3.03e-01 | 70.6% | 52.0% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 32.0 | 3.35e-01 | 100.0% | 63.5% |
| 3we9A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 38.0 | 2.62e-01 | 75.0% | 51.4% |
| 2fsfB04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.54 | 44.0 | 3.21e-01 | 95.6% | 59.0% |
| 4ex8A00 | 3.40.1790.10 | Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain | 0.52 | 43.0 | 2.96e-01 | 100.0% | 90.4% |
| 2hoqA02 | 1.10.150.520 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.52 | 42.0 | 3.99e-01 | 85.3% | 100.0% |
| 4gzrC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.51 | 36.0 | 3.77e-01 | 77.9% | 83.6% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.51 | 37.0 | 3.48e-01 | 88.2% | 59.8% |
| 1tf5A04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.51 | 42.0 | 3.14e-01 | 97.1% | 35.2% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5011341 | 4049.1.1.0 ↗ | alpha superhelices › alpha-helical domain in siroheme synthase middle domains-like › alpha-helical domain in siroheme synthase middle domains-like › alpha-helical domain in siroheme synthase middle domains-like | 0.66 | 45.0 | 4.71e-01 | 76.5% | 80.0% |
| 4271696 | 306.7.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › Trigger factor ribosome-binding domain › Trigger factor ribosome-binding domain › Trigger_N | 0.64 | 51.0 | 4.18e-01 | 95.6% | 46.2% |
| 3241444 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.64 | 51.0 | 3.70e-01 | 92.6% | 66.4% |
| 3319076 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.64 | 46.0 | 4.27e-01 | 77.9% | 63.3% |
| 3331123 | 101.35.1.23 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › Ovate | 0.62 | 41.0 | 4.33e-01 | 97.1% | 78.3% |
| 3940867 | 632.22.1.67 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › DUF842 | 0.60 | 47.0 | 4.32e-01 | 88.2% | 63.2% |
| 4044670 | 306.7.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › Trigger factor ribosome-binding domain › Trigger factor ribosome-binding domain › Trigger_N | 0.60 | 53.0 | 4.29e-01 | 100.0% | 63.8% |
| None | — | 0.59 | 50.0 | 3.52e-01 | 95.6% | 90.7% | |
| 4939889 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.59 | 45.0 | 3.77e-01 | 83.8% | 63.3% |
| 1503071 | 632.2.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › GA | 0.59 | 36.0 | 3.91e-01 | 77.9% | 75.0% |
| 3228773 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 45.0 | 3.63e-01 | 86.8% | 52.4% |
| 4669918 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.58 | 46.0 | 3.25e-01 | 92.6% | 61.8% |
| 4291138 | 306.7.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › Trigger factor ribosome-binding domain › Trigger factor ribosome-binding domain › Trigger_N | 0.58 | 47.0 | 3.89e-01 | 89.7% | 68.8% |
| 5073312 | 2006.1.1.18 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 | 0.57 | 48.0 | 3.37e-01 | 95.6% | 88.7% |
| 3175548 | 524.1.1.1 ↗ | alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC | 0.56 | 46.0 | 3.54e-01 | 97.1% | 78.9% |
| 3225635 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.55 | 46.0 | 3.32e-01 | 97.1% | 59.1% |
| 3933803 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 37.0 | 2.61e-01 | 97.1% | 20.6% |
| 4628161 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.53 | 38.0 | 3.29e-01 | 76.5% | 52.2% |
| 3651135 | 3788.1.1.20 ↗ | alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › VIN3_C | 0.53 | 35.0 | 3.45e-01 | 85.3% | 61.3% |
| 3797620 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.53 | 43.0 | 3.15e-01 | 91.2% | 39.0% |
| 397246 | 161.1.1.1 ↗ | alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › SecA_SW | 0.51 | 44.0 | 3.07e-01 | 97.1% | 30.6% |
| 3813587 | 109.4.1.1262 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long | 0.51 | 36.0 | 2.50e-01 | 73.5% | 31.8% |
| 3335296 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.51 | 31.0 | 2.73e-01 | 94.1% | 42.0% |
| 3722863 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 39.0 | 2.57e-01 | 85.3% | 17.6% |
| 4329267 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.50 | 36.0 | 2.34e-01 | 77.9% | 30.1% |
D6
medium
residues 1149-1223_1257-1291
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4o1pD02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.54 | 39.0 | 3.00e-01 | 72.7% | 60.1% |
| 3kalB05 | 3.30.1490.50 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Glutathione synthase lid domain | 0.52 | 26.0 | 3.20e-01 | 92.7% | 81.4% |