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IMGVR_UViG_3300002481_000004-3300002481-JGI24020J35080_100034835

Arc-Vir

IMGVR_UViG_3300002481_000004-3300002481-JGI24020J35080_100034835

Quality

85.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 11-127_162-190
PDB
Domain cluster: representative
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.67 60.0 5.94e-01 98.6% 97.5%
3ljbA00 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.66 60.0 5.18e-01 100.0% 64.8%
3vr4B04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.65 39.0 3.87e-01 85.6% 56.3%
5zbqA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 48.0 3.84e-01 85.6% 41.5%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 47.0 3.99e-01 80.8% 82.7%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.60 45.0 4.51e-01 91.1% 76.0%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 37.0 3.76e-01 78.1% 59.7%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 42.0 4.04e-01 72.6% 69.0%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.59 40.0 4.56e-01 83.6% 92.6%
4gycA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 40.0 3.52e-01 93.2% 46.4%
4akvA02 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 49.0 4.48e-01 90.4% 97.4%
2wyhB04 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.58 35.0 4.04e-01 85.6% 85.1%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 49.0 3.99e-01 91.1% 85.0%
7uzqK01 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.57 38.0 2.85e-01 89.0% 27.2%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.57 43.0 3.87e-01 88.4% 57.5%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 37.0 3.67e-01 80.1% 61.2%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 44.0 3.53e-01 82.2% 43.7%
3ls1A00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.56 32.0 3.34e-01 84.2% 58.6%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.55 34.0 3.40e-01 84.2% 57.8%
2jbrA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 43.0 3.99e-01 92.5% 65.4%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 47.0 3.87e-01 93.8% 81.5%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 46.0 3.83e-01 91.1% 87.4%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 46.0 4.22e-01 89.7% 92.0%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 48.0 4.04e-01 95.2% 91.0%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 46.0 3.86e-01 92.5% 85.4%
3ok8A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 47.0 4.13e-01 95.2% 89.5%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 45.0 3.99e-01 90.4% 89.0%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.53 44.0 4.53e-01 93.2% 93.7%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 46.0 3.93e-01 95.2% 86.9%
4wjg400 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.53 46.0 3.78e-01 93.2% 83.9%
4oo2A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 46.0 4.16e-01 96.6% 75.2%
1w33A00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.53 40.0 3.79e-01 90.4% 65.2%
2uxwA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 39.0 4.16e-01 89.7% 86.9%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.52 43.0 4.02e-01 93.2% 69.7%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 28.0 3.22e-01 76.7% 69.7%
4bjmC00 1.20.58.1680 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 38.0 3.39e-01 77.4% 56.3%
4y9jA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 40.0 3.98e-01 87.0% 79.2%
3q1xA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.51 34.0 3.52e-01 85.6% 69.8%
6vq6G02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.51 42.0 3.90e-01 87.0% 75.5%
3wmeA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.51 46.0 3.51e-01 95.9% 80.9%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.51 45.0 4.14e-01 96.6% 90.9%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.51 37.0 3.71e-01 95.2% 72.5%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.51 35.0 4.11e-01 84.2% 100.0%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 34.0 3.60e-01 85.6% 77.3%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.50 41.0 3.61e-01 87.7% 81.7%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4030151 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.77 60.0 6.20e-01 93.2% 87.4%
3165030 601.19.1.3 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F 0.70 63.0 5.71e-01 98.6% 80.5%
3784055 192.24.1.0 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.68 47.0 4.96e-01 70.5% 87.7%
3270091 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.67 58.0 5.21e-01 93.2% 94.1%
3464251 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.66 57.0 4.83e-01 92.5% 70.8%
5048730 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.65 42.0 4.06e-01 93.2% 55.9%
3770290 4177.1.1.41 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › EVC2_like 0.64 56.0 5.15e-01 97.9% 77.4%
3281928 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.63 38.0 3.85e-01 89.7% 58.4%
3298761 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.63 47.0 3.99e-01 78.8% 99.6%
4593595 3835.1.1.0 alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein 0.62 49.0 4.30e-01 83.6% 100.0%
3476662 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.61 40.0 3.42e-01 93.8% 42.9%
3530722 4177.1.1.150 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF4745 0.61 50.0 5.22e-01 91.8% 95.6%
3646025 632.22.1.67 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › DUF842 0.61 50.0 5.21e-01 87.7% 100.0%
3610803 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.61 55.0 4.36e-01 100.0% 85.7%
5062884 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.59 52.0 4.62e-01 95.9% 89.5%
3237547 150.1.1.31 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety 0.59 46.0 3.79e-01 82.2% 47.6%
3983527 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.59 40.0 4.14e-01 86.3% 74.1%
3262220 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.58 46.0 3.72e-01 84.2% 77.5%
3346986 3711.1.1.4 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 0.57 46.0 4.13e-01 85.6% 63.4%
3925122 4177.1.1.4 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD 0.57 48.0 4.15e-01 88.4% 78.6%
3293846 192.29.1.34 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF677 0.57 43.0 3.50e-01 80.1% 97.9%
4320633 2004.1.1.433 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.57 41.0 2.91e-01 73.3% 53.2%
4999598 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.57 38.0 4.00e-01 89.7% 75.4%
5072700 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.57 50.0 4.08e-01 95.9% 66.7%
5027387 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.57 40.0 4.19e-01 74.7% 80.8%
4226755 2004.1.1.782 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23, AAA_29, SbcC_Walker_B 0.56 39.0 2.75e-01 70.5% 60.4%
3477262 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.55 41.0 3.89e-01 82.9% 64.0%
5046993 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.55 41.0 3.76e-01 80.1% 62.0%
3699443 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 40.0 4.46e-01 76.7% 100.0%
3207621 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.54 36.0 3.57e-01 81.5% 64.4%
3930842 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.54 45.0 3.63e-01 91.1% 81.4%
4018045 3285.1.1.1 alpha duplicates or obligate multimers › Alix V domain › Alix V domain › Alix V domain › ALIX_LYPXL_bnd 0.53 44.0 3.94e-01 90.4% 79.5%
5037182 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 46.0 4.03e-01 95.2% 86.4%
3489372 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.53 48.0 4.09e-01 100.0% 82.6%
3710920 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.53 35.0 3.29e-01 85.6% 56.0%
3359325 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.52 34.0 3.65e-01 75.3% 75.2%
3615123 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.52 40.0 3.81e-01 81.5% 81.7%
3583324 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.52 44.0 4.39e-01 99.3% 85.2%
3390900 174.1.1.29 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 0.52 36.0 3.49e-01 80.1% 64.4%
3551963 601.19.1.23 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Tektin 0.51 42.0 3.99e-01 88.4% 86.3%
3464835 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.51 35.0 3.72e-01 82.2% 81.6%
D2 medium residues 128-161_191-252
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04233.20 best Phage_Mu_F 46.4 8.60e-12 77.1% 48.2%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4032640 601.19.1.3 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F 0.58 48.0 3.29e-01 88.5% 45.2%
D3 medium residues 253-349
PDB
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1k78A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 39.0 4.68e-01 77.3% 74.2%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.69 55.0 5.58e-01 91.8% 88.3%
4biuE01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.66 38.0 3.79e-01 76.3% 55.1%
1ofcX04 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.66 45.0 4.60e-01 76.3% 72.3%
3crmA02 1.10.287.890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain 0.66 37.0 4.00e-01 82.5% 64.3%
5xsoA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 40.0 4.38e-01 82.5% 78.9%
3wvoC02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.64 44.0 4.04e-01 72.2% 70.8%
4abxA02 6.10.140.1090 Special › Helix non-globular › Helix Hairpins › 0.64 36.0 3.83e-01 76.3% 62.1%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 45.0 3.39e-01 76.3% 46.5%
3on2A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 49.0 3.96e-01 85.6% 54.2%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.62 37.0 3.67e-01 79.4% 55.9%
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.61 46.0 4.48e-01 84.5% 72.5%
3owaA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 42.0 3.47e-01 71.1% 92.4%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 44.0 4.21e-01 76.3% 86.6%
4im7A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.59 51.0 4.04e-01 97.9% 69.7%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.59 44.0 4.03e-01 80.4% 68.2%
1hw1A02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.58 50.0 4.31e-01 93.8% 79.5%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 44.0 4.31e-01 78.4% 90.2%
4cybD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 52.0 4.30e-01 100.0% 87.1%
2w53B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 43.0 3.63e-01 80.4% 70.5%
4xxiA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.57 41.0 3.64e-01 85.6% 50.3%
1gpjA03 1.10.1200.70 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glutamyl tRNA-reductase dimerization domain 0.57 46.0 4.89e-01 99.0% 97.6%
3rlfG01 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.56 50.0 3.66e-01 100.0% 45.4%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.56 43.0 4.09e-01 80.4% 93.8%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.56 47.0 4.13e-01 91.8% 86.1%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.56 40.0 3.73e-01 96.9% 58.9%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.56 46.0 3.95e-01 89.7% 61.3%
2cfoA05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.55 43.0 4.27e-01 84.5% 80.8%
2raeA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 44.0 4.01e-01 88.7% 71.5%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.55 39.0 3.26e-01 73.2% 82.2%
5d0yA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.55 45.0 3.90e-01 91.8% 85.8%
3frqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 43.0 3.55e-01 86.6% 48.4%
1xqrA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.54 36.0 2.63e-01 77.3% 24.7%
2lvfA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.53 40.0 3.87e-01 85.6% 69.3%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.53 41.0 3.57e-01 84.5% 73.5%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.53 39.0 3.55e-01 78.4% 85.7%
3gziA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 40.0 3.20e-01 82.5% 47.3%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.52 36.0 4.09e-01 77.3% 90.9%
3vnxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 47.0 3.73e-01 100.0% 51.8%
4mk6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 43.0 3.51e-01 91.8% 49.5%
2r4gA02 1.10.10.1970 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › TERT catalytic subunit-like 0.52 29.0 3.34e-01 75.3% 78.1%
1z72A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.52 43.0 3.38e-01 93.8% 66.2%
1v9mA02 1.20.1690.10 Mainly Alpha › Up-down Bundle › V-type ATP synthase subunit C fold › V-type ATP synthase subunit C domain 0.51 43.0 4.30e-01 99.0% 89.1%
1z6oM00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 45.0 3.66e-01 100.0% 53.4%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.51 44.0 4.05e-01 94.8% 84.8%
2au5A00 1.20.120.590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like 0.51 36.0 3.34e-01 75.3% 85.3%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4195219 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.73 59.0 5.85e-01 85.6% 90.0%
3261605 198.1.1.2 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 0.68 48.0 5.16e-01 80.4% 88.7%
4667148 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.67 48.0 3.67e-01 74.2% 52.7%
3927465 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.65 57.0 4.11e-01 97.9% 86.4%
3705127 509.1.1.0 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain 0.63 40.0 4.06e-01 80.4% 64.2%
5018515 5050.1.1.53 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC 0.63 55.0 4.40e-01 99.0% 90.5%
1031092 3705.1.1.1 alpha arrays › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › T2SS_PulS_OutS 0.62 49.0 5.02e-01 90.7% 89.5%
4939128 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.61 42.0 4.75e-01 83.5% 98.6%
4988441 5069.1.1.10 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF4079 0.60 45.0 3.95e-01 78.4% 89.3%
3176957 109.4.1.3459 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30191 0.59 44.0 2.84e-01 76.3% 20.7%
3219872 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.58 43.0 3.85e-01 79.4% 92.1%
3616671 604.1.1.155 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF29142 0.58 42.0 4.30e-01 76.3% 77.9%
3394211 109.4.1.338 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RIC1 0.58 36.0 2.82e-01 80.4% 28.4%
3291236 191.1.1.18 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_14 0.57 46.0 4.08e-01 86.6% 72.1%
3390921 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.57 34.0 3.69e-01 88.7% 70.0%
3444490 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.57 46.0 4.01e-01 88.7% 57.9%
3588238 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.57 48.0 3.74e-01 92.8% 60.0%
3214191 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 42.0 3.95e-01 76.3% 89.6%
3260300 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.56 45.0 3.68e-01 86.6% 45.4%
3941776 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 47.0 3.75e-01 93.8% 88.3%
3749998 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 40.0 3.78e-01 75.3% 78.3%
3522864 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 41.0 3.96e-01 77.3% 87.3%
5012015 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 3.98e-01 94.8% 82.3%
5070939 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 48.0 3.82e-01 96.9% 83.5%
3695505 604.3.1.11 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 0.55 40.0 3.83e-01 76.3% 89.6%
4646569 4994.1.1.1 alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 0.55 46.0 4.65e-01 91.8% 97.9%
4017639 1065.1.1.0 alpha bundles › SPX domain › SPX domain › SPX domain 0.53 43.0 3.54e-01 86.6% 73.1%
4382271 3949.1.1.1 alpha arrays › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › tRNA delta(2)-isopentenylpyrophosphate transferase helical insertion domain › IPPT 0.53 37.0 2.90e-01 73.2% 71.7%
3892495 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.53 39.0 3.66e-01 77.3% 85.8%
3939816 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.53 39.0 3.68e-01 77.3% 85.8%
3638257 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.53 39.0 3.60e-01 76.3% 90.8%
3896730 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 41.0 3.64e-01 81.4% 95.6%
3400200 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 41.0 3.79e-01 87.6% 64.8%
3694245 5051.1.1.10 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 0.52 44.0 2.91e-01 99.0% 74.8%
3192708 109.42.1.0 alpha superhelices › Repetitive alpha hairpins › E3 ubiquitin-protein ligase SHPRH first helical domain › E3 ubiquitin-protein ligase SHPRH first helical domain 0.52 46.0 3.76e-01 100.0% 87.4%
3177431 101.1.1.94 alpha arrays › HTH › HTH › Three-helical HTH › Reb1_MybAD 0.52 35.0 4.05e-01 70.1% 98.6%
4556484 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 42.0 3.86e-01 86.6% 82.4%
5079385 3930.1.1.3 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical 0.52 37.0 3.33e-01 86.6% 53.3%
4331551 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.50 37.0 3.22e-01 78.4% 52.0%
3282251 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.50 37.0 3.36e-01 77.3% 75.2%
4948675 3930.1.1.3 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical 0.50 39.0 3.47e-01 94.8% 57.9%
D4 medium residues 350-414
PDB
CATH (65)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3f7wA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.77 55.0 4.88e-01 75.4% 87.9%
3u97A00 3.10.450.530 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 0.74 56.0 5.34e-01 81.5% 76.6%
5ih0A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.72 50.0 4.38e-01 72.3% 84.9%
2gu3A02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.71 50.0 5.09e-01 73.8% 79.4%
4ix3A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.71 50.0 4.19e-01 75.4% 87.6%
2kr0A01 2.30.29.70 Mainly Beta › Roll › PH-domain like › Proteasomal ubiquitin receptor Rpn13/ADRM1 0.70 53.0 4.50e-01 83.1% 85.8%
2ymsC00 2.40.10.480 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.70 47.0 4.50e-01 75.4% 60.0%
2aq5A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.70 54.0 3.40e-01 84.6% 18.0%
5xd6B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.69 50.0 4.49e-01 78.5% 96.8%
1inyA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.68 51.0 3.13e-01 80.0% 33.5%
4l68A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.68 50.0 4.26e-01 80.0% 82.7%
4ozuA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.68 55.0 3.43e-01 87.7% 19.3%
1flgA00 2.140.10.10 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › Quinoprotein alcohol dehydrogenase-like superfamily 0.67 53.0 3.07e-01 84.6% 31.3%
2gu3A01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.67 50.0 5.02e-01 78.5% 81.5%
1zylA01 3.30.200.70 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › 0.67 47.0 4.60e-01 73.8% 84.3%
1h4iA00 2.140.10.10 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › Quinoprotein alcohol dehydrogenase-like superfamily 0.67 53.0 3.07e-01 86.2% 28.7%
5ighA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.67 45.0 4.10e-01 70.8% 85.2%
6zxfz01 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.66 51.0 4.13e-01 83.1% 90.2%
2p4oA01 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.66 54.0 3.54e-01 90.8% 81.5%
2wsuB02 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.66 49.0 3.79e-01 80.0% 86.8%
4gq1A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.66 53.0 3.32e-01 87.7% 43.2%
4kujA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.65 49.0 3.74e-01 81.5% 95.3%
4k3yC00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.65 55.0 3.45e-01 93.8% 57.2%
1sgoA01 3.30.2280.10 Alpha Beta › 2-Layer Sandwich › copper amine oxidase-like fold › Hypothetical protein (hspc210) 0.65 46.0 3.90e-01 75.4% 50.9%
4fvkA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.65 56.0 3.46e-01 95.4% 51.5%
4nsxA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.64 51.0 3.25e-01 87.7% 29.0%
8axiA01 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.64 51.0 3.25e-01 90.8% 39.6%
5m8cB01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.63 49.0 3.10e-01 84.6% 29.6%
4innA00 2.40.128.520 Mainly Beta › Beta Barrel › Lipocalin › 0.63 46.0 3.64e-01 80.0% 80.1%
8aimG01 3.10.450.20 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Bacteriophage PBS2, uracil-glycosylase inhibitor 0.63 47.0 4.42e-01 81.5% 82.7%
3jamg01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.63 51.0 3.26e-01 89.2% 74.5%
4ifaA01 3.40.33.10 Alpha Beta › 3-Layer(aba) Sandwich › Pathogenesis-related Protein p14a › CAP 0.62 53.0 3.53e-01 96.9% 86.0%
2m7oA00 3.10.450.400 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Uncharacterised protein PF15513, DUF4651 0.62 43.0 4.28e-01 80.0% 68.6%
4w82A01 3.90.180.10 Alpha Beta › Alpha-Beta Complex › Quinone Oxidoreductase; Chain A, domain 1 › Medium-chain alcohol dehydrogenases, catalytic domain 0.62 51.0 4.00e-01 95.4% 80.5%
2x5gA00 3.30.720.60 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.62 43.0 3.85e-01 72.3% 72.5%
3a5vA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.62 42.0 3.69e-01 70.8% 98.0%
4adiA02 3.30.67.20 Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Rubella membrane glycoprotein E1, domain 2 0.62 48.0 4.40e-01 86.2% 68.2%
4dsdA00 3.40.1420.30 Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › 0.62 43.0 3.48e-01 75.4% 38.1%
1y96A00 2.30.30.100 Mainly Beta › Roll › SH3 type barrels. › 0.61 43.0 3.93e-01 73.8% 66.3%
2xepB01 3.10.450.280 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.61 48.0 4.01e-01 86.2% 49.1%
7snsB01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.61 43.0 3.28e-01 75.4% 84.6%
3ap9A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.61 48.0 3.72e-01 87.7% 60.9%
3jcuO01 2.40.160.30 Mainly Beta › Beta Barrel › Porin › Photosystem II, cytochrome c-550 precursor 0.61 44.0 3.28e-01 78.5% 71.0%
4agiA00 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.60 49.0 3.19e-01 90.8% 53.2%
4gyiA02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.60 45.0 3.98e-01 81.5% 100.0%
1ijqA01 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.60 46.0 3.13e-01 84.6% 87.0%
2x0qA01 3.30.310.280 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.60 45.0 3.69e-01 84.6% 54.9%
4g59B00 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.60 41.0 3.12e-01 72.3% 87.7%
1qmnA01 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.59 44.0 3.48e-01 80.0% 90.0%
4jpqA00 2.60.40.1190 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 49.0 3.56e-01 100.0% 46.1%
4fdtB00 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.59 45.0 2.76e-01 83.1% 92.7%
6m90A02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.59 48.0 3.13e-01 90.8% 25.4%
3i8tA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.58 43.0 3.46e-01 81.5% 65.7%
3u2aA00 3.30.450.310 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.58 48.0 4.00e-01 90.8% 68.8%
1iucA00 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.58 48.0 3.12e-01 93.8% 41.0%
4mjgA00 3.30.2030.30 Alpha Beta › 2-Layer Sandwich › TBP-like › 0.57 43.0 3.20e-01 83.1% 62.7%
3oe3C00 2.40.128.200 Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor 0.56 42.0 3.92e-01 86.2% 95.5%
3gjyA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 38.0 2.54e-01 72.3% 39.8%
1f9cA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.55 44.0 3.72e-01 93.8% 100.0%
3rr1A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.55 44.0 3.60e-01 93.8% 88.3%
3uxuA00 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.54 44.0 3.45e-01 95.4% 71.1%
8bddA02 2.70.98.70 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.54 42.0 2.74e-01 90.8% 90.3%
3mx7A00 2.40.128.180 Mainly Beta › Beta Barrel › Lipocalin › 0.53 42.0 3.83e-01 89.2% 94.4%
3c6kA01 3.30.160.110 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Sirohaem synthase, central domain 0.53 39.0 3.48e-01 80.0% 69.1%
3ednA01 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.50 37.0 3.01e-01 80.0% 77.6%
ECOD (79)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3709245 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.82 57.0 5.14e-01 80.0% 55.3%
3956000 4312.1.1.0 a+b two layers › RelE-like › RelE-like › RelE-like 0.77 61.0 5.97e-01 84.6% 84.3%
1146563 4312.1.1.1 a+b two layers › RelE-like › RelE-like › RelE-like › BrnT_toxin 0.74 56.0 5.37e-01 81.5% 77.6%
5012193 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.73 55.0 3.80e-01 80.0% 45.7%
3927330 243.6.1.0 a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain 0.73 54.0 4.92e-01 78.5% 82.4%
5057301 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.72 58.0 3.83e-01 86.2% 23.4%
3815404 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.72 62.0 3.94e-01 96.9% 42.1%
2773872 5.1.5.79 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40, WDR90_beta-prop_4th 0.72 52.0 3.22e-01 76.9% 14.5%
3310878 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.71 62.0 3.55e-01 95.4% 24.3%
3255575 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.70 58.0 3.63e-01 89.2% 86.9%
3329275 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.70 59.0 3.83e-01 95.4% 48.7%
3217309 243.6.1.4 a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain › Pre-PUA 0.69 53.0 4.74e-01 81.5% 81.1%
3554889 5.1.3.251 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › PF28327 0.69 55.0 3.44e-01 87.7% 19.4%
3660499 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.69 59.0 3.80e-01 95.4% 49.3%
3662169 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.68 59.0 3.62e-01 96.9% 38.9%
3348409 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.67 57.0 3.51e-01 96.9% 35.8%
3264756 4075.1.1.2 a+b complex topology › RGC domain › RGC domain › RGC domain › PF29130 0.67 51.0 4.36e-01 80.0% 90.0%
4991847 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.67 55.0 3.64e-01 90.8% 58.5%
3255777 4075.1.1.2 a+b complex topology › RGC domain › RGC domain › RGC domain › PF29130 0.67 51.0 4.45e-01 80.0% 94.7%
3802207 5.1.3.67 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.67 54.0 3.47e-01 89.2% 38.7%
6423 243.3.1.13 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF5590 0.67 50.0 5.03e-01 78.5% 81.5%
3833385 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.67 56.0 4.30e-01 93.8% 59.3%
3309970 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.66 52.0 3.30e-01 86.2% 83.5%
3965134 9.1.1.0 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.66 52.0 4.40e-01 87.7% 90.4%
1310956 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.66 53.0 3.35e-01 87.7% 43.1%
1031143 6043.1.1.3 a+b two layers › yfeY-like › yfeY-like › yfeY-like › CAP_assoc_N 0.66 49.0 4.69e-01 78.5% 81.1%
5023556 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.66 53.0 3.55e-01 90.8% 57.8%
3800964 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.66 54.0 3.38e-01 90.8% 43.1%
4025506 5.1.4.4 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,DUF1899,WD40_4 0.65 53.0 3.23e-01 87.7% 27.1%
3786550 5.1.4.219 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › DPPIV_N 0.65 51.0 3.04e-01 84.6% 18.3%
5019856 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.65 49.0 4.50e-01 81.5% 85.9%
4507137 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.65 56.0 3.30e-01 95.4% 90.7%
3973549 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.65 51.0 3.32e-01 86.2% 43.7%
3644344 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.65 55.0 3.55e-01 96.9% 43.9%
3656952 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.64 49.0 4.00e-01 80.0% 74.8%
4990437 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.64 53.0 3.63e-01 92.3% 63.0%
5031673 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.64 43.0 3.69e-01 70.8% 57.1%
3947367 206.1.1.35 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH_6_hur 0.64 53.0 3.46e-01 90.8% 61.9%
3445637 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.63 53.0 3.41e-01 92.3% 57.7%
3399544 5.1.3.25 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Mcl1_mid 0.63 50.0 3.23e-01 86.2% 36.3%
4676847 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.63 52.0 3.19e-01 90.8% 44.0%
4380331 295.1.1.27 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PF25991 0.63 47.0 4.66e-01 81.5% 82.9%
3526234 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.63 52.0 3.26e-01 92.3% 39.5%
3794257 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.63 52.0 3.19e-01 92.3% 41.9%
3475508 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.63 52.0 3.17e-01 90.8% 90.8%
3273236 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.63 52.0 3.16e-01 92.3% 42.8%
3280945 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.62 52.0 3.20e-01 92.3% 42.4%
3211832 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.62 46.0 3.05e-01 81.5% 22.5%
3392759 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.62 54.0 3.41e-01 100.0% 29.3%
3932539 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.62 47.0 3.05e-01 87.7% 17.3%
3959715 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.62 51.0 3.32e-01 92.3% 56.3%
3763927 331.9.1.9 a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › PF26171 0.62 45.0 3.83e-01 78.5% 62.4%
None 0.62 51.0 3.15e-01 92.3% 41.6%
3562175 10.1.1.5 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Pentaxin 0.61 46.0 3.25e-01 83.1% 70.0%
5039633 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.61 46.0 4.49e-01 84.6% 73.0%
3640527 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.61 52.0 3.62e-01 95.4% 82.8%
3204590 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.61 50.0 3.09e-01 92.3% 23.6%
3637832 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.60 50.0 3.05e-01 93.8% 55.3%
3225818 207.1.1.52 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FBA_2 0.60 50.0 3.37e-01 90.8% 40.4%
3624850 331.9.1.9 a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › PF26171 0.60 44.0 3.77e-01 78.5% 63.8%
3237828 331.9.1.9 a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › PF26171 0.60 43.0 3.67e-01 76.9% 63.6%
4929797 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.60 41.0 4.27e-01 72.3% 78.0%
3536489 331.9.1.5 a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › AP4E_app_platf 0.60 44.0 3.77e-01 78.5% 66.7%
4999447 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.59 45.0 3.01e-01 83.1% 56.8%
5050718 300.1.1.6 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › Regulator_TrmB 0.59 49.0 3.67e-01 92.3% 84.2%
3288997 304.125.1.2 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in Api92-like proteins › ferredoxin-like domain in Api92-like proteins › DUF6461 0.59 44.0 3.44e-01 81.5% 78.0%
3603162 243.6.1.0 a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain 0.58 41.0 3.79e-01 76.9% 77.8%
1107861 3513.1.1.1 a+b two layers › Putative lipoprotein LppA › Putative lipoprotein LppA › Putative lipoprotein LppA › DUF4853 0.57 43.0 3.20e-01 83.1% 62.7%
5021016 243.6.1.0 a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain 0.56 39.0 3.56e-01 75.4% 73.7%
3739251 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.56 44.0 2.65e-01 89.2% 26.1%
3432796 5.1.10.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 12-bladed 0.56 42.0 4.04e-01 86.2% 93.8%
5072132 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.55 37.0 3.53e-01 70.8% 66.3%
3572323 5.1.4.6 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,ANAPC4_WD40 0.55 46.0 3.11e-01 96.9% 40.0%
3580534 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.54 40.0 2.72e-01 86.2% 27.9%
4970384 243.6.1.9 a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain › TGT_C2 0.54 41.0 3.77e-01 81.5% 64.7%
4272149 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.54 46.0 3.08e-01 90.8% 36.1%
4978331 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.53 38.0 3.75e-01 75.4% 71.4%
4608279 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.53 38.0 3.85e-01 76.9% 86.2%
3301044 12.3.1.3 beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Aldose_epim 0.51 33.0 2.44e-01 70.8% 21.0%