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IMGVR_UViG_3300002481_000051-3300002481-JGI24020J35080_100021721

Arc-Vir

IMGVR_UViG_3300002481_000051-3300002481-JGI24020J35080_100021721

Identity

Kingdom:
archaea

Quality

90.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 186-371
PDB
Domain cluster: rep: NC_049448.1__YP_009882481.1__HYP77_gp49__00049__D273-480
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2fokA03 3.40.91.30 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.83 75.0 7.76e-01 97.8% 99.4%
2e52B01 3.40.91.70 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Type II restriction endonuclease, HindIII 0.72 68.0 6.35e-01 100.0% 82.6%
1ob8A00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.68 43.0 5.40e-01 78.5% 100.0%
4p1zA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.66 39.0 4.59e-01 88.2% 84.3%
7kx9A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.65 41.0 4.54e-01 88.7% 78.5%
1b96A00 3.40.600.10 Alpha Beta › 3-Layer(aba) Sandwich › ECO RV Endonuclease; Chain A › DNA mismatch repair MutH/Restriction endonuclease, type II 0.62 45.0 4.12e-01 74.2% 84.0%
3rqiA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 39.0 4.63e-01 91.9% 92.9%
3crnA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 38.0 4.46e-01 88.2% 87.6%
2jk1A00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 37.0 4.27e-01 88.2% 81.2%
4q7eA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 38.0 4.46e-01 88.7% 90.4%
7lzaA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 37.0 4.48e-01 88.7% 94.9%
2qv0A00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 37.0 4.49e-01 86.6% 93.4%
1udxA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 44.0 4.56e-01 78.0% 91.4%
1dc1A01 3.40.91.10 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.58 48.0 4.57e-01 88.7% 91.9%
1tkjA00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.56 48.0 4.24e-01 93.5% 96.8%
4tkzA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.54 33.0 3.84e-01 91.9% 85.4%
5ib0A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.53 33.0 3.75e-01 79.0% 82.5%
7b7pA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.53 44.0 3.95e-01 89.2% 93.2%
1q7lA00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.53 39.0 3.90e-01 75.3% 95.3%
3n5fA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.53 46.0 3.98e-01 94.6% 97.9%
1cg2A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.52 45.0 3.96e-01 93.0% 93.5%
3aayA02 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.52 31.0 3.54e-01 83.3% 79.4%
3on5B02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 37.0 3.96e-01 77.4% 87.9%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4999520 2008.1.1.44 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › FokI_cleav_dom 0.91 73.0 7.65e-01 99.5% 89.4%
11018 2008.1.1.44 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › FokI_cleav_dom 0.83 76.0 7.56e-01 99.5% 91.7%
5004622 2008.1.1.16 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.81 54.0 6.57e-01 84.9% 100.0%
5057822 2008.1.1.16 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.81 56.0 6.36e-01 88.7% 91.0%
4963007 2008.1.1.16 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.79 54.0 5.90e-01 84.4% 83.2%
4953911 2008.1.1.16 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.78 48.0 6.05e-01 80.1% 100.0%
4950783 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.71 46.0 5.22e-01 84.4% 83.4%
4946872 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.69 53.0 5.58e-01 78.5% 93.3%
3266028 7590.1.1.0 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs 0.68 41.0 4.95e-01 88.7% 90.8%
4942425 2008.1.1.141 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_19 0.67 43.0 5.23e-01 79.6% 96.0%
3274283 2008.1.1.82 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RRG7 0.67 55.0 5.97e-01 89.8% 100.0%
4974216 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.67 56.0 5.91e-01 90.3% 98.8%
3695358 7590.1.1.3 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi,ArgoMid 0.67 43.0 4.55e-01 89.8% 71.5%
3583806 7590.1.1.6 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › ArgoMid 0.66 43.0 4.52e-01 88.7% 70.6%
3687944 7590.1.1.2 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi 0.66 44.0 4.52e-01 88.7% 69.7%
3685090 7590.1.1.0 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs 0.65 43.0 4.50e-01 89.8% 71.8%
3968346 2007.1.3.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.65 43.0 4.90e-01 91.9% 87.9%
3520053 7590.1.1.3 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi,ArgoMid 0.63 42.0 4.30e-01 88.7% 69.1%
5044647 2008.1.1.0 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.60 47.0 5.05e-01 89.8% 98.7%
4198344 2495.1.1.2 ↗ a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.59 32.0 3.96e-01 83.3% 84.3%
4383523 2008.1.1.188 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF30180 0.58 43.0 3.90e-01 75.8% 76.7%
3787978 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.56 48.0 4.15e-01 94.6% 99.7%
4971864 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.54 46.0 4.08e-01 92.5% 96.2%
3590815 2011.1.1.0 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases 0.53 46.0 4.04e-01 95.2% 89.0%
4956788 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.53 46.0 4.14e-01 94.1% 98.8%
3291183 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.52 44.0 3.85e-01 92.5% 100.0%
4958240 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.52 44.0 3.83e-01 94.6% 93.1%
4944222 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.51 44.0 3.92e-01 94.1% 96.2%
D2 high residues 378-496
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.76 52.0 5.12e-01 91.6% 65.1%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.70 52.0 5.66e-01 89.1% 93.8%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.61 42.0 3.85e-01 81.5% 54.8%
2ebnA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.60 37.0 2.85e-01 80.7% 25.6%
8d8lN01 1.10.287.1480 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 30.0 3.43e-01 73.1% 65.1%
2yayA02 1.20.1670.10 Mainly Alpha › Up-down Bundle › all-alpha NTP pyrophosphatase › Type II deoxyuridine triphosphatase 0.59 31.0 3.03e-01 76.5% 44.4%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.57 32.0 3.94e-01 73.1% 88.0%
2dwkA00 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.56 42.0 3.78e-01 78.2% 88.8%
3owaA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 38.0 3.39e-01 71.4% 92.4%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.55 44.0 4.12e-01 84.9% 87.7%
5e1wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 38.0 3.36e-01 70.6% 80.4%
3pieA02 3.30.1370.250 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.53 38.0 4.10e-01 85.7% 89.0%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 34.0 3.55e-01 73.9% 70.6%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 37.0 3.84e-01 84.0% 76.8%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.53 44.0 4.52e-01 92.4% 100.0%
6qpqB00 1.10.10.580 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E 0.52 33.0 3.82e-01 79.0% 92.6%
1t6sA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 36.0 4.14e-01 89.1% 100.0%
7bqiA01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.51 37.0 3.49e-01 77.3% 100.0%
4hkaA01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 44.0 3.27e-01 93.3% 48.6%
1k8kA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.50 30.0 3.32e-01 82.4% 75.0%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2321219 1016.1.1.1 ↗ alpha arrays › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Pan3_PK 0.70 30.0 2.91e-01 100.0% 35.1%
5005967 7592.1.1.6 ↗ a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › Csa3_N 0.65 31.0 2.89e-01 79.0% 35.2%
5055279 1075.1.2.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.60 50.0 4.16e-01 89.1% 54.6%
3658365 3543.1.1.4 ↗ alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF716 0.57 47.0 3.62e-01 89.9% 97.9%
3718646 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.57 49.0 3.75e-01 92.4% 78.1%
5038241 3896.1.1.0 ↗ alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase 0.57 44.0 3.51e-01 85.7% 40.7%
3974731 601.52.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › Flagellar hook-associated protein 1 helical domain › Flagellar hook-associated protein 1 helical domain › FlgK_D1 0.56 50.0 3.66e-01 100.0% 70.6%
4998156 873.1.1.0 ↗ a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain 0.53 42.0 3.86e-01 85.7% 79.4%
3653902 2484.1.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.52 38.0 3.20e-01 78.2% 80.0%
4946324 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.52 37.0 3.11e-01 74.8% 82.7%
4233720 601.25.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.51 39.0 3.62e-01 80.7% 78.1%
4989946 873.1.1.0 ↗ a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain 0.51 36.0 3.75e-01 83.2% 79.1%
4959456 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.51 41.0 3.70e-01 87.4% 67.6%
3935332 192.2.1.1 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.51 35.0 3.45e-01 71.4% 80.8%
4573100 2484.1.1.206 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70, FGGY_C 0.51 35.0 3.03e-01 70.6% 58.4%
4025088 109.4.1.418 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Condensin2nSMC 0.51 38.0 2.37e-01 79.0% 14.0%
3288303 5051.1.1.3 ↗ alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SSF 0.50 42.0 2.83e-01 93.3% 83.5%
D3 medium residues 1-47
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07498.19 best Rho_N 25.1 1.90e-05 85.1% 83.7%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1y02A01 1.10.720.140 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.79 62.0 5.25e-01 87.2% 52.6%
1e7lA02 1.10.720.10 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.79 70.0 6.63e-01 100.0% 90.9%
3e0zA00 1.20.58.1400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Domain of unknown function DUF3837 0.72 51.0 4.01e-01 78.7% 39.3%
3l0oA01 1.10.720.10 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.72 60.0 6.03e-01 100.0% 95.9%
3q23A08 1.20.140.110 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.69 54.0 3.76e-01 91.5% 26.6%
2yguC00 1.10.238.190 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › 0.68 57.0 4.38e-01 100.0% 68.6%
3i01A01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 56.0 3.87e-01 97.9% 31.1%
3u60A02 1.20.272.50 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › Bacteriophage clamp loader A subunit, A' domain 0.64 53.0 4.55e-01 95.7% 69.2%
7qv0F01 1.10.1200.10 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like 0.62 49.0 4.27e-01 95.7% 98.8%
1ax4A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.62 50.0 3.26e-01 100.0% 99.2%
2a7oA00 1.10.1740.100 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Set2, Rpb1 interacting domain 0.59 53.0 4.10e-01 100.0% 47.0%
2erbA01 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.55 43.0 3.36e-01 87.2% 78.5%
2r11D00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 37.0 2.37e-01 76.6% 71.2%
1hjrA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 42.0 3.09e-01 100.0% 33.5%
4uobA01 1.10.1670.10 Mainly Alpha › Orthogonal Bundle › Endonuclease Iii, domain 2 › Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 0.52 36.0 2.92e-01 91.5% 31.9%
1zq9A02 1.10.8.480 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 39.0 3.34e-01 100.0% 98.0%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3709590 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.88 80.0 5.58e-01 100.0% 33.6%
3724166 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.88 78.0 6.97e-01 97.9% 72.3%
3702963 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.87 78.0 5.84e-01 100.0% 44.5%
5053068 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.87 69.0 7.38e-01 85.1% 100.0%
5049323 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.87 78.0 5.31e-01 100.0% 31.4%
3472431 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.85 67.0 7.12e-01 85.1% 100.0%
4241485 130.1.1.20 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › HeH 0.83 65.0 6.21e-01 85.1% 74.5%
3590596 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.83 67.0 6.88e-01 89.4% 97.8%
3190964 130.1.1.20 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › HeH 0.83 70.0 6.63e-01 91.5% 78.2%
3336810 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.83 68.0 6.96e-01 91.5% 100.0%
3712494 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.82 70.0 6.69e-01 95.7% 85.5%
4623858 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.82 68.0 6.91e-01 91.5% 100.0%
3252664 130.1.1.31 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › RNF34L-like_3rd 0.82 68.0 6.45e-01 91.5% 80.0%
4428371 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.81 67.0 6.86e-01 91.5% 95.6%
3797432 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.81 68.0 6.51e-01 91.5% 81.1%
4136263 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.81 66.0 6.79e-01 91.5% 95.6%
3271283 130.1.1.20 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › HeH 0.81 67.0 6.16e-01 91.5% 80.0%
3440160 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.81 69.0 7.00e-01 97.9% 100.0%
3261240 130.1.1.1 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SAP 0.80 63.0 6.65e-01 85.1% 100.0%
4433184 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.80 65.0 6.23e-01 91.5% 81.8%
3611122 130.1.1.32 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SAP_RNF34_RFFL (DEPRECATED) 0.80 65.0 6.24e-01 91.5% 81.8%
3715853 130.1.1.31 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › RNF34L-like_3rd 0.80 66.0 6.56e-01 91.5% 93.8%
3923899 130.1.1.15 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › PADR1_N 0.79 68.0 4.89e-01 100.0% 35.0%
3127 130.1.1.7 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Endonuc-dimeris 0.79 70.0 6.68e-01 100.0% 92.6%
3172891 130.1.1.16 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Ish1 0.78 70.0 6.87e-01 100.0% 98.0%
3881311 130.1.1.32 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SAP_RNF34_RFFL (DEPRECATED) 0.77 63.0 6.39e-01 91.5% 95.6%
3191284 130.1.1.16 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Ish1 0.77 67.0 6.57e-01 97.9% 94.0%
3838872 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.77 65.0 6.27e-01 97.9% 89.1%
4545934 130.1.1.29 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SLS1_N 0.77 65.0 5.81e-01 100.0% 70.0%
3198528 130.1.1.16 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Ish1 0.75 65.0 6.20e-01 100.0% 87.3%
1233457 130.1.1.3 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Rho_N 0.72 60.0 5.99e-01 100.0% 94.0%
4386708 130.1.1.49 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › PF27388 0.68 55.0 4.70e-01 97.9% 55.0%
4027117 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.67 54.0 5.16e-01 100.0% 94.8%
3563151 101.1.2.106 ↗ alpha arrays › HTH › HTH › winged helix domain › Tam41_Mmp37 0.66 56.0 3.91e-01 100.0% 29.7%
3511398 101.1.2.106 ↗ alpha arrays › HTH › HTH › winged helix domain › Tam41_Mmp37 0.65 58.0 4.00e-01 100.0% 31.0%
3819046 524.1.1.1 ↗ alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC 0.62 51.0 3.38e-01 100.0% 48.9%
4078503 152.1.2.1 ↗ alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 0.60 49.0 4.55e-01 100.0% 78.5%
4876269 152.1.1.1 ↗ alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RPB6 › RNA_pol_Rpb6 0.59 49.0 4.58e-01 100.0% 82.3%
4294364 3457.1.1.1 ↗ alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Peptidase_A24 0.57 43.0 3.05e-01 93.6% 78.5%
4991391 5058.1.1.0 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.55 36.0 2.88e-01 100.0% 31.0%
4943027 7064.1.1.1 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.55 44.0 3.18e-01 95.7% 80.6%
3272128 109.6.1.3 ↗ alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF_N 0.53 37.0 2.73e-01 76.6% 44.7%
D4 medium residues 79-155
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vsmA03 2.60.40.4340 Mainly Beta › Sandwich › Immunoglobulin-like › 0.69 50.0 4.67e-01 100.0% 62.8%
6t5kC00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.65 48.0 3.43e-01 77.9% 92.9%
2acaA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.65 44.0 3.37e-01 70.1% 79.9%
2g7jA00 3.90.1150.40 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Protein of unknown function DUF2002 0.63 44.0 3.94e-01 74.0% 83.0%
1hdhA02 3.30.1120.10 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.63 53.0 5.30e-01 92.2% 94.8%
5mu3B00 3.40.50.12050 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 46.0 3.60e-01 79.2% 41.7%
3vz9B00 3.30.457.50 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › Chromosome segregation protein Spc25 0.59 43.0 3.93e-01 77.9% 68.9%
3q6aB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 47.0 3.88e-01 97.4% 51.5%
8es5A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 49.0 4.01e-01 97.4% 60.1%
2wcoA03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.55 37.0 3.31e-01 70.1% 93.0%
2jpiA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.55 43.0 4.02e-01 100.0% 68.8%
4wqkA00 3.30.460.40 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.53 37.0 2.89e-01 72.7% 72.6%
5inwA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.53 38.0 3.49e-01 83.1% 56.5%
4abyD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 43.0 2.88e-01 90.9% 83.0%
1yprA00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.51 40.0 3.54e-01 90.9% 91.2%
2z0fA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.51 43.0 3.99e-01 98.7% 72.5%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5067782 331.1.1.0 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.77 47.0 4.97e-01 79.2% 68.6%
4982613 331.1.1.0 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.76 49.0 5.26e-01 81.8% 76.9%
4937221 331.1.1.0 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.71 45.0 4.64e-01 100.0% 66.7%
4680096 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.71 50.0 5.00e-01 74.0% 77.5%
5028032 331.1.1.1 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › TBP 0.69 45.0 4.44e-01 85.7% 61.2%
4028555 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.65 48.0 4.88e-01 77.9% 89.3%
3411657 12.3.1.19 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Gal_mutarotas_2 0.65 46.0 3.07e-01 74.0% 85.7%
6638 241.7.1.2 ↗ a+b two layers › Type III secretory system chaperone-like › YgaC/TfoX-N like › YgaC/TfoX-N like › DUF2002 0.63 44.0 3.94e-01 74.0% 83.0%
4995145 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.63 41.0 3.99e-01 71.4% 60.0%
185625 4099.1.1.7 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Ctf19_RWD1 0.62 45.0 3.97e-01 77.9% 56.8%
5048170 331.10.2.0 ↗ a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.62 43.0 4.25e-01 100.0% 68.8%
2130268 4099.1.1.7 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Ctf19_RWD1 0.61 45.0 4.42e-01 79.2% 80.0%
3268245 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.61 46.0 4.23e-01 80.5% 70.0%
3647550 331.2.1.0 ↗ a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.58 43.0 4.22e-01 100.0% 71.8%
3288251 331.3.1.9 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › AHSA1 0.56 49.0 3.87e-01 100.0% 47.1%
4609138 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.55 46.0 3.80e-01 100.0% 48.7%
3282089 331.3.1.0 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.55 46.0 3.60e-01 98.7% 42.4%
3291702 331.3.1.0 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.54 49.0 3.85e-01 97.4% 51.6%
3931300 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.54 46.0 4.38e-01 100.0% 80.0%
3962822 331.3.1.2 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Ring_hydroxyl_A 0.54 45.0 3.77e-01 92.2% 88.1%
3468562 331.1.1.5 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › OGG_N 0.52 40.0 3.89e-01 93.5% 73.3%
3818511 331.2.1.0 ↗ a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.51 45.0 3.84e-01 100.0% 67.7%
3574215 10.1.1.17 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.50 44.0 3.17e-01 94.8% 63.3%