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IMGVR_UViG_3300002514_000850-3300002514-JGI25133J35611_100016089

Arc-Vir

Identity

Accession:: IMGVR_UViG_3300002514_000850-3300002514-JGI25133J35611_100016089 ↗
Kingdom:: archaea

Quality

89.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 238-400_402-458

PDB

Domain cluster: rep: BML_08182015_1_5m_scaffold_19_prodigal-single.1__X__X__00139__D33-210

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF13578.13 best	Methyltransf_24	34.0	6.60e-08	58.6%	86.9%

CATH (75)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2gpyB00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.78	58.0	6.27e-01	99.1%	87.5%
3gu3A01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.78	57.0	6.48e-01	96.4%	97.6%
8k1fC01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.77	62.0	6.57e-01	99.1%	92.3%
4pioA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.77	59.0	6.44e-01	95.9%	95.0%
3a7eA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.76	65.0	6.69e-01	100.0%	91.5%
8c9vA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.76	61.0	6.66e-01	100.0%	99.4%
4pcaB00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.75	64.0	6.47e-01	99.1%	88.5%
3duwA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.75	65.0	6.59e-01	99.1%	90.4%
2hnkA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.75	66.0	6.56e-01	99.1%	88.2%
2bm8B02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.74	55.0	6.18e-01	95.9%	97.6%
3ntvA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.73	62.0	6.37e-01	98.6%	91.4%
6g80B01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.73	65.0	6.51e-01	99.1%	91.9%
4xrpC01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.73	56.0	6.24e-01	95.9%	99.4%
1jqdA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.71	65.0	5.91e-01	95.9%	92.0%
1u2zA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.70	49.0	5.41e-01	96.4%	86.1%
4ymhD00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.70	62.0	6.11e-01	99.1%	87.2%
1npdB02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.70	47.0	5.59e-01	95.9%	100.0%
5iceA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.69	55.0	5.26e-01	96.8%	72.1%
1nytA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.68	44.0	5.32e-01	90.5%	98.6%
1xmxA01	3.40.50.10770	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like)	0.68	40.0	4.93e-01	88.2%	89.4%
1wkvA03	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.68	33.0	4.70e-01	94.5%	100.0%
2x7xA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.67	42.0	5.21e-01	91.4%	100.0%
3c3kA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.67	42.0	5.16e-01	95.9%	99.3%
2qe6A00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.66	61.0	5.68e-01	96.8%	90.2%
7cpxA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.66	59.0	5.04e-01	96.4%	61.4%
3kjxA03	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.66	42.0	5.07e-01	95.9%	97.9%
2wteA01	3.40.50.11700	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.66	40.0	4.92e-01	87.7%	94.9%
4o5aA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.65	41.0	5.00e-01	96.4%	97.1%
5c3uA02	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.65	31.0	4.43e-01	94.1%	100.0%
3l6uA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.64	42.0	5.05e-01	95.5%	100.0%
4rsmA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.64	41.0	4.80e-01	95.5%	92.0%
4zeoH02	3.40.50.10470	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2	0.64	45.0	5.21e-01	89.5%	98.8%
3gbvA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.64	41.0	4.92e-01	95.9%	95.3%
3axsA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.64	60.0	5.23e-01	100.0%	69.6%
4iuyA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.64	55.0	5.22e-01	90.0%	94.1%
1fuyB01	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.64	37.0	4.18e-01	95.5%	74.4%
3gdgA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.64	54.0	5.09e-01	90.0%	90.6%
3d8uB02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.63	42.0	4.98e-01	95.9%	97.3%
3vywA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.63	56.0	5.49e-01	96.8%	86.0%
5hsgA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.63	42.0	4.87e-01	95.9%	91.9%
1w6uD00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.63	55.0	5.03e-01	91.4%	89.0%
4z0tA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.63	54.0	5.21e-01	90.0%	93.0%
3hcwA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.63	40.0	4.82e-01	95.9%	97.2%
5b1hA02	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.63	31.0	4.37e-01	70.9%	100.0%
1xg5B00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.62	54.0	5.24e-01	91.4%	96.3%
2g5cA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.61	42.0	4.74e-01	87.7%	89.9%
7e6iA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.61	47.0	5.19e-01	81.4%	100.0%
1gcaA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.61	42.0	4.79e-01	95.9%	94.4%
3crnA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.61	33.0	4.23e-01	88.2%	89.9%
3hl0A01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.60	39.0	4.56e-01	91.4%	89.9%
1vb5B02	3.40.50.10470	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2	0.60	47.0	5.10e-01	94.1%	97.2%
2wjwA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.59	39.0	4.40e-01	95.9%	87.1%
2vqmA00	3.40.800.20	Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain	0.58	48.0	3.91e-01	85.0%	48.6%
1a3cA00	3.40.50.2020	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.58	38.0	4.33e-01	94.1%	86.7%
1ujnA01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.58	38.0	4.37e-01	91.4%	89.4%
1tjyA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.57	39.0	4.53e-01	94.5%	97.4%
3idfA00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.57	36.0	4.39e-01	86.8%	99.3%
4wzzA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.56	39.0	4.52e-01	95.0%	98.1%
3ecsD02	3.40.50.10470	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2	0.56	46.0	4.91e-01	93.6%	98.0%
3ujpA02	3.40.50.1980	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain	0.56	31.0	4.01e-01	90.0%	99.1%
4wutA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.55	38.0	4.43e-01	95.0%	100.0%
4y9tA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.55	40.0	4.41e-01	93.2%	92.6%
5ywwA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.55	36.0	3.84e-01	97.3%	75.4%
6hqvA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	36.0	4.08e-01	89.1%	87.6%
5ix8A02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.54	37.0	4.28e-01	93.2%	97.5%
2rjoA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.54	37.0	4.16e-01	93.6%	89.6%
1o94A02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.52	39.0	4.37e-01	83.6%	100.0%
6gt9A02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.51	38.0	4.18e-01	96.4%	96.6%
3ai2A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.51	46.0	4.32e-01	96.8%	86.3%
2gn0B01	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.51	40.0	4.07e-01	83.6%	99.6%
3zdbA01	3.40.50.1010	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease	0.50	35.0	4.03e-01	73.6%	98.7%
1tdjA01	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.50	39.0	3.95e-01	80.9%	98.7%
6a8mA01	3.40.350.10	Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain	0.50	37.0	4.09e-01	98.2%	95.9%
1v71A01	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.50	40.0	4.09e-01	85.0%	99.5%
5ilgB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.50	45.0	4.29e-01	96.8%	85.3%

ECOD (83)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4985740	2003.1.5.80 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_24	0.81	59.0	6.80e-01	95.9%	98.8%
2389407	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.78	64.0	6.58e-01	99.1%	89.4%
5010840	2003.1.5.80 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_24	0.77	61.0	6.55e-01	99.1%	93.2%
4967531	2003.1.5.41 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RMNT_CmcI	0.77	60.0	5.83e-01	98.2%	72.5%
None	—		0.77	64.0	6.00e-01	98.2%	72.1%
3445291	2003.1.5.80 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_24	0.77	65.0	6.05e-01	98.2%	72.8%
None	—		0.76	50.0	5.91e-01	96.8%	92.3%
3025909	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.76	61.0	6.56e-01	100.0%	96.3%
4962328	2003.1.5.81 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25	0.75	57.0	6.09e-01	96.8%	87.7%
3318932	2003.1.5.121 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF1442	0.75	44.0	5.69e-01	88.6%	98.4%
3955014	2003.1.5.41 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RMNT_CmcI	0.75	62.0	6.05e-01	97.7%	79.6%
5046935	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.75	62.0	6.49e-01	97.7%	92.2%
4236808	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.73	66.0	6.50e-01	100.0%	89.1%
2439987	2003.1.5.80 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_24	0.73	65.0	6.44e-01	99.1%	89.8%
4998506	2003.1.5.66 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11	0.72	58.0	6.08e-01	96.4%	91.0%
4358885	2003.1.5.79 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23	0.71	66.0	5.89e-01	96.4%	90.1%
3197431	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.70	62.0	6.00e-01	99.1%	83.3%
3635157	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.70	62.0	6.04e-01	99.1%	85.0%
3664522	2003.1.5.31 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS	0.69	64.0	4.94e-01	96.8%	74.7%
4025743	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.69	51.0	5.53e-01	99.1%	90.3%
3741064	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.68	65.0	6.04e-01	100.0%	83.7%
3726570	2003.1.5.14 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3	0.68	65.0	5.94e-01	100.0%	87.1%
3194067	2003.1.1.61 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › KR	0.67	57.0	4.30e-01	96.4%	38.6%
4215684	2003.1.1.188 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Methyltransf_12, KR	0.67	58.0	4.09e-01	96.4%	31.8%
3423322	2003.1.7.2 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B	0.67	40.0	5.08e-01	92.3%	100.0%
2502973	2007.1.2.11 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4	0.67	41.0	5.13e-01	90.5%	100.0%
4288608	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.66	59.0	4.80e-01	96.8%	53.4%
3188704	2003.1.1.188 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Methyltransf_12, KR	0.66	58.0	4.10e-01	96.4%	32.1%
3738575	2003.1.5.71 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_33	0.66	61.0	5.28e-01	96.4%	86.9%
4675739	2003.1.5.67 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12	0.66	61.0	5.44e-01	96.8%	71.0%
5040125	2003.1.5.71 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_33	0.66	61.0	5.22e-01	96.4%	82.1%
None	—		0.66	59.0	4.76e-01	96.8%	52.3%
4518850	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.66	61.0	4.66e-01	96.8%	46.2%
4363289	2003.1.5.67 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12	0.66	59.0	4.95e-01	96.8%	58.3%
4016566	2003.1.5.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2	0.66	55.0	5.19e-01	96.4%	73.1%
1734342	7592.1.1.6 ↗	a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › Csa3_N	0.66	40.0	4.89e-01	88.2%	93.6%
4123589	2003.1.5.53 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr	0.66	63.0	5.08e-01	100.0%	64.6%
2483672	2003.4.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes	0.66	35.0	4.32e-01	95.5%	82.1%
1412651	2003.1.5.71 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_33	0.65	60.0	5.17e-01	95.9%	80.8%
3972431	2003.1.5.80 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_24	0.65	60.0	6.10e-01	99.1%	96.4%
4444241	2003.1.5.364 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAD_binding_4, Methyltransf_12	0.65	59.0	4.00e-01	96.8%	28.9%
4015230	2003.1.5.67 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12	0.65	58.0	4.82e-01	96.4%	55.9%
3188044	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.65	58.0	5.10e-01	94.5%	80.6%
3725529	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.65	56.0	5.33e-01	91.4%	94.2%
3186462	2003.1.1.148 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short, KR	0.65	58.0	5.10e-01	94.5%	85.1%
None	—		0.65	59.0	4.69e-01	96.4%	51.6%
2483890	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.64	34.0	4.14e-01	91.4%	78.3%
3519741	2007.1.2.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I	0.64	39.0	4.90e-01	94.1%	100.0%
4035998	2003.1.5.67 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12	0.64	58.0	4.81e-01	96.4%	57.0%
2329746	2003.1.5.67 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12	0.64	59.0	5.49e-01	96.8%	82.6%
3697184	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.64	57.0	5.20e-01	95.5%	85.2%
3594490	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.63	57.0	5.47e-01	95.9%	84.9%
153143	2003.1.5.49 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_30	0.63	56.0	4.96e-01	96.8%	66.7%
3644155	2003.1.5.46 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS	0.63	54.0	5.14e-01	88.6%	79.2%
3690476	2003.1.1.69 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2	0.63	58.0	5.24e-01	98.6%	91.9%
5050989	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.63	53.0	4.80e-01	88.6%	94.5%
9086	2003.1.1.3 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short	0.63	54.0	5.17e-01	91.4%	96.5%
3973534	2003.1.5.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases	0.62	54.0	5.45e-01	96.8%	90.7%
4945173	2005.1.1.0 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains	0.60	42.0	4.51e-01	89.1%	82.2%
None	—		0.60	41.0	4.70e-01	91.4%	92.1%
4952835	2005.1.1.11 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3	0.59	40.0	4.51e-01	89.1%	89.4%
4938945	7592.1.1.3 ↗	a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › DUF6293_N	0.58	38.0	4.60e-01	87.7%	100.0%
135916	2005.1.1.3 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp	0.57	36.0	4.39e-01	86.8%	99.3%
3582142	2007.1.2.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I	0.55	39.0	4.19e-01	96.8%	84.3%
3586946	2005.2.1.1 ↗	a/b three-layered sandwiches › HUP domain-like › YdcF › YdcF › DUF218	0.55	47.0	4.52e-01	91.4%	92.4%
4958691	7518.1.1.1 ↗	a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C	0.54	41.0	4.32e-01	76.8%	93.8%
4971799	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.54	39.0	4.34e-01	78.2%	92.6%
4943077	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.54	38.0	4.33e-01	78.2%	95.8%
4414077	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.54	38.0	4.40e-01	80.0%	99.4%
4245182	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.53	40.0	4.28e-01	81.8%	88.9%
3353265	2003.1.7.2 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B	0.53	46.0	4.68e-01	92.7%	97.7%
3609546	2003.1.7.2 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B	0.53	46.0	4.62e-01	92.3%	100.0%
3974717	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.53	38.0	4.31e-01	79.1%	100.0%
4501791	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.53	38.0	4.36e-01	80.0%	98.8%
4436110	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.53	35.0	4.16e-01	97.3%	98.0%
4164599	2007.1.2.5 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Bmp	0.53	42.0	3.70e-01	96.4%	56.4%
3576311	2003.1.7.2 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B	0.52	45.0	4.64e-01	91.8%	97.7%
4322077	2005.1.1.11 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3	0.52	42.0	4.18e-01	84.1%	99.6%
3229670	2003.4.1.1 ↗	a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP	0.52	34.0	4.05e-01	92.3%	96.7%
3845121	2007.1.2.4 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor	0.51	39.0	4.00e-01	94.5%	80.0%
5000464	2003.1.9.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins	0.51	47.0	4.72e-01	98.6%	96.9%
3929890	2007.1.2.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I	0.51	40.0	4.03e-01	82.7%	93.3%
4027002	2003.1.5.111 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Rsm22	0.51	46.0	3.72e-01	99.1%	91.1%

D2 medium residues 1-61_97-149_209-216_218-235

PDB

Domain cluster: representative

CATH (60)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1g9rA00	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.75	67.0	5.28e-01	96.4%	87.0%
7zvjA01	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.74	67.0	5.44e-01	97.1%	92.8%
2j0aA00	3.90.550.50	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A ›	0.73	68.0	5.58e-01	100.0%	82.7%
6yv8A01	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.73	66.0	5.62e-01	97.1%	88.6%
1qg8A00	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.73	67.0	5.54e-01	98.6%	89.1%
7zllA01	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.72	65.0	5.13e-01	97.1%	86.9%
6h21A01	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.72	65.0	5.67e-01	97.1%	98.5%
4p02A02	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.71	66.0	5.45e-01	100.0%	96.3%
5tz8A01	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.71	64.0	5.34e-01	96.4%	86.7%
3tztA00	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.71	65.0	5.43e-01	98.6%	87.1%
3bcvA00	3.90.550.10	Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	0.70	62.0	5.54e-01	95.0%	100.0%
2r60A02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.66	54.0	4.63e-01	85.7%	85.6%
3hdcA01	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.65	45.0	4.74e-01	71.4%	86.7%
5i45A00	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.64	52.0	4.61e-01	84.3%	85.6%
1lqtA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.64	46.0	3.99e-01	74.3%	74.3%
3oy2A02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.63	50.0	4.20e-01	83.6%	81.5%
3tsaA02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.63	49.0	4.57e-01	82.9%	85.3%
1v4vA02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.62	50.0	4.84e-01	84.3%	96.2%
1gg1A00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.61	43.0	3.31e-01	72.9%	87.0%
3t5tA02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.61	51.0	4.62e-01	88.6%	93.1%
2iyfB02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.61	48.0	4.61e-01	82.9%	90.9%
3ia7A02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.60	47.0	4.52e-01	82.9%	92.0%
7vm0A02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.60	47.0	4.52e-01	82.1%	93.0%
7bv3A01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.58	51.0	4.15e-01	95.0%	98.4%
1k4kB00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.57	51.0	4.54e-01	98.6%	82.4%
2vchA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.57	51.0	4.13e-01	97.1%	90.3%
6vloD01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.56	50.0	4.37e-01	95.7%	99.5%
3tosA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.56	48.0	3.99e-01	93.6%	74.9%
5djsA02	3.40.50.11380	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.56	50.0	4.54e-01	97.9%	79.8%
1vjtA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.56	44.0	4.79e-01	94.3%	100.0%
1ycoA00	3.40.718.10	Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase	0.55	50.0	3.98e-01	97.9%	95.3%
2x0dA01	3.40.50.11090	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.55	49.0	4.29e-01	96.4%	87.6%
3hb7A00	3.40.50.850	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like	0.55	48.0	4.37e-01	96.4%	94.7%
5l9aB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.54	47.0	3.58e-01	93.6%	92.2%
4wqmA03	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.54	45.0	4.66e-01	97.9%	94.7%
4dimA01	3.40.50.20	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.53	41.0	4.38e-01	87.1%	93.3%
4wnyA00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.53	46.0	4.81e-01	99.3%	100.0%
2xlpB01	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.53	47.0	3.52e-01	96.4%	82.3%
3tovA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.53	47.0	4.46e-01	97.1%	88.3%
1af7A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.53	46.0	4.11e-01	94.3%	87.1%
2z4tA02	3.40.50.11120	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sialyltransferase, N-terminal GT-B Rossman nucleotide-binding domain	0.52	47.0	4.05e-01	99.3%	91.6%
3lqkA00	3.40.50.1950	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like	0.52	48.0	4.27e-01	99.3%	99.0%
6tdxG01	3.40.1380.10	Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit	0.52	48.0	4.14e-01	100.0%	81.8%
3hbmA01	3.40.50.11190	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.52	45.0	4.60e-01	95.0%	100.0%
4g1vA03	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.52	43.0	4.40e-01	100.0%	91.2%
2bgiA02	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.52	46.0	4.53e-01	97.9%	94.8%
1u7zC00	3.40.50.10300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CoaB-like	0.52	46.0	3.97e-01	97.9%	91.8%
2hdoA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.52	46.0	4.59e-01	96.4%	97.2%
1qfjA02	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.51	43.0	4.44e-01	97.9%	94.1%
1fdrA02	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.51	46.0	4.47e-01	97.9%	92.8%
1f0kA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.51	45.0	4.18e-01	95.7%	94.3%
1c96A03	3.30.499.10	Alpha Beta › 2-Layer Sandwich › Aconitase; domain 3 › Aconitase, domain 3	0.51	45.0	4.21e-01	96.4%	77.7%
3gxbA00	3.40.50.410	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain	0.51	46.0	4.23e-01	97.9%	96.6%
4pg4A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.51	46.0	4.38e-01	97.9%	91.9%
6ldqA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.51	44.0	4.09e-01	95.0%	88.9%
3oqvA00	3.40.50.11710	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cyclodipeptide synthase	0.51	45.0	3.94e-01	97.1%	98.6%
5if3B00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.51	45.0	3.98e-01	98.6%	85.6%
1krhA03	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.50	42.0	4.35e-01	97.9%	93.3%
2gt1A01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.50	44.0	4.18e-01	94.3%	95.7%
2xyqA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.50	45.0	3.54e-01	97.1%	65.2%

ECOD (92)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3415120	7516.1.1.180 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Fringe, Glyco_transf_7C, CHGN	0.75	70.0	4.47e-01	100.0%	40.0%
4940749	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.75	70.0	5.42e-01	100.0%	74.5%
4996472	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.75	69.0	5.27e-01	99.3%	69.3%
4967525	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.75	70.0	5.34e-01	100.0%	72.0%
3590002	7516.1.1.6 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_8	0.74	68.0	5.45e-01	99.3%	90.7%
10277	7516.1.1.6 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_8	0.74	67.0	5.30e-01	97.1%	87.1%
3410224	7516.1.1.37 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › CHGN	0.74	69.0	5.17e-01	99.3%	92.2%
4634680	7516.1.1.26 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_tranf_2_3	0.74	69.0	4.77e-01	100.0%	49.9%
4959776	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.74	69.0	5.04e-01	100.0%	61.4%
3243577	7516.1.1.112 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Fringe, CHGN	0.74	69.0	5.34e-01	100.0%	79.2%
4090833	7516.1.1.102 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2, Glyco_trans_2_3	0.74	69.0	4.78e-01	100.0%	50.4%
3218231	7516.1.1.78 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › DUF1647	0.74	67.0	4.99e-01	97.9%	73.4%
3645255	7516.1.1.102 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2, Glyco_trans_2_3	0.73	68.0	4.60e-01	100.0%	49.5%
3212511	7516.1.1.78 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › DUF1647	0.73	68.0	5.04e-01	100.0%	73.9%
4972771	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.73	68.0	5.16e-01	99.3%	70.6%
4957466	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.73	68.0	5.15e-01	100.0%	67.6%
3547050	7516.1.1.37 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › CHGN	0.73	68.0	5.57e-01	99.3%	87.1%
3901916	7516.1.1.85 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_tranf_2_4	0.73	68.0	5.08e-01	100.0%	75.1%
4996452	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.73	68.0	4.99e-01	99.3%	60.9%
5025467	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.73	67.0	5.01e-01	100.0%	62.9%
5077065	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.73	67.0	5.23e-01	99.3%	73.0%
5029760	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.73	68.0	5.14e-01	100.0%	69.4%
3478023	7516.1.1.85 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_tranf_2_4	0.72	67.0	5.04e-01	100.0%	80.9%
3260470	7516.1.1.14 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › GNT-I	0.72	67.0	4.74e-01	100.0%	55.5%
5057136	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.72	67.0	5.67e-01	100.0%	85.5%
4997918	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.72	66.0	5.09e-01	99.3%	69.0%
3308049	7516.1.1.89 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › HPAT	0.72	67.0	4.85e-01	100.0%	67.5%
3654075	7516.1.1.21 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_64	0.71	66.0	5.29e-01	100.0%	76.6%
4929429	7516.1.1.26 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_tranf_2_3	0.71	66.0	4.64e-01	100.0%	49.4%
None	—		0.71	66.0	5.01e-01	100.0%	69.8%
5048624	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.71	65.0	5.73e-01	97.9%	98.0%
3675399	7516.1.1.21 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_64	0.71	66.0	5.27e-01	100.0%	77.0%
4530978	7516.1.1.0 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases	0.71	65.0	5.28e-01	100.0%	87.3%
3163601	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.71	65.0	6.04e-01	98.6%	90.9%
3180991	7516.1.1.18 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Anp1	0.71	65.0	4.85e-01	100.0%	81.8%
4011976	7516.1.1.0 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases	0.70	65.0	4.87e-01	100.0%	83.9%
3174806	7516.1.1.28 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_24	0.70	64.0	5.25e-01	97.9%	93.5%
1181023	7516.1.1.6 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_8	0.70	56.0	6.05e-01	85.7%	100.0%
5070480	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.70	65.0	4.94e-01	100.0%	60.3%
5056206	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.70	64.0	5.30e-01	100.0%	84.1%
3782404	7516.1.1.18 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Anp1	0.69	64.0	4.66e-01	100.0%	88.4%
3975958	7516.1.1.0 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases	0.68	62.0	5.08e-01	100.0%	81.9%
5030628	7516.1.1.0 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases	0.67	62.0	5.62e-01	100.0%	100.0%
3264162	7512.1.1.33 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_41	0.66	52.0	4.28e-01	82.1%	84.9%
4955676	7512.1.1.32 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4	0.65	50.0	4.63e-01	80.0%	88.0%
4974944	7512.1.1.3 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1	0.64	51.0	4.75e-01	82.9%	88.8%
4990031	7512.1.1.32 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4	0.63	48.0	4.22e-01	80.0%	70.0%
3933336	7512.1.1.1 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT	0.63	50.0	3.46e-01	85.7%	95.3%
5079827	7512.1.1.3 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1	0.63	49.0	4.50e-01	82.9%	80.5%
4958353	7512.1.1.3 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1	0.62	50.0	4.56e-01	85.7%	80.5%
3847905	7512.1.1.83 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT, EryCIII-like_C	0.62	51.0	3.44e-01	87.9%	90.5%
1881563	7512.1.1.20 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › EryCIII-like_C	0.61	48.0	4.44e-01	82.1%	84.1%
5072238	7512.1.1.12 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_tran_28_C	0.61	48.0	4.18e-01	82.1%	73.7%
3278942	7512.1.1.20 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › EryCIII-like_C	0.60	47.0	4.35e-01	82.1%	81.7%
4976510	7512.1.1.12 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_tran_28_C	0.60	48.0	4.40e-01	83.6%	85.6%
5078598	7512.1.1.12 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_tran_28_C	0.60	47.0	4.40e-01	82.9%	86.3%
3324679	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.60	55.0	4.41e-01	97.9%	96.2%
4987758	2003.1.6.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like › Tubulin	0.59	46.0	3.82e-01	82.9%	99.6%
3353160	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.58	52.0	4.25e-01	97.9%	93.7%
3339080	7512.1.1.77 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_N	0.57	51.0	4.21e-01	97.9%	98.8%
4996066	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.57	44.0	4.10e-01	82.9%	81.7%
3813339	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.56	51.0	4.20e-01	98.6%	92.2%
4997914	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.56	50.0	4.70e-01	99.3%	100.0%
3173554	7567.1.1.1 ↗	a/b three-layered sandwiches › LmbE-like › LmbE-like › LmbE-like › PIG-L	0.56	51.0	4.02e-01	99.3%	86.2%
5067910	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.56	50.0	4.40e-01	97.9%	91.2%
4998416	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.55	48.0	4.37e-01	97.1%	88.1%
4994284	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.55	48.0	4.33e-01	97.9%	88.0%
3415869	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.55	46.0	4.56e-01	90.7%	89.3%
4988215	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.55	47.0	4.26e-01	94.3%	95.4%
5038565	7512.1.1.31 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4	0.54	40.0	4.47e-01	97.9%	100.0%
4993509	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.54	48.0	4.25e-01	97.1%	91.0%
4996695	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.54	47.0	4.33e-01	96.4%	98.9%
5055503	7512.1.1.31 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4	0.54	47.0	4.45e-01	96.4%	100.0%
3575417	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.54	48.0	3.93e-01	98.6%	76.5%
5026398	7514.1.1.1 ↗	a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1	0.53	46.0	4.38e-01	92.9%	91.5%
5009872	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.53	48.0	4.39e-01	99.3%	100.0%
4996468	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.53	46.0	4.13e-01	97.1%	88.8%
4999374	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.53	46.0	4.15e-01	97.1%	87.0%
4961874	2005.1.1.3 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp	0.53	46.0	4.77e-01	98.6%	100.0%
3399778	7512.1.1.1 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT	0.53	47.0	3.84e-01	99.3%	95.6%
4220892	7519.1.1.1 ↗	a/b three-layered sandwiches › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP-synt	0.52	48.0	3.81e-01	100.0%	59.1%
3653986	2005.1.1.3 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp	0.52	47.0	4.44e-01	97.9%	100.0%
3834277	2005.1.1.3 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp	0.52	46.0	4.23e-01	95.7%	92.3%
5029129	7512.1.1.30 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4	0.52	45.0	4.17e-01	96.4%	94.6%
4963821	2005.1.1.3 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp	0.52	45.0	4.68e-01	98.6%	100.0%
5023494	2003.1.1.51 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DFP	0.52	46.0	4.06e-01	97.9%	96.1%
4988574	2005.1.1.0 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains	0.51	43.0	4.53e-01	96.4%	100.0%
3976132	7514.1.1.0 ↗	a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain	0.51	43.0	4.07e-01	91.4%	90.6%
3339708	2005.1.1.43 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CHX17_2nd	0.51	47.0	4.52e-01	100.0%	93.1%
4426464	7514.1.1.1 ↗	a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1	0.50	42.0	4.29e-01	97.9%	91.3%
3981866	2005.1.1.3 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp	0.50	46.0	4.37e-01	99.3%	95.1%
4000201	2005.1.1.36 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12	0.50	42.0	4.28e-01	100.0%	92.6%

D3 medium residues 62-96_150-181_183-208

PDB

Domain cluster: rep: IMGVR_UViG_3300025326_000018-3300025326-Ga0209342_100001273__D57-98_163-210

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1n5uA02	1.10.246.10	Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 ›	0.53	37.0	3.81e-01	72.0%	84.4%
2uvaG06	1.20.930.70	Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A ›	0.52	36.0	3.33e-01	71.0%	84.9%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5023341	4009.1.1.1 ↗	alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom	0.54	37.0	4.08e-01	72.0%	97.1%
3699966	148.1.3.10 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_6	0.51	43.0	4.07e-01	98.9%	78.2%

D4 medium residues 507-665

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01973.24 best	MptE-like	67.0	2.60e-18	98.7%	81.9%

CATH (64)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3k94A00	3.40.50.10240	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin pyrophosphokinase, catalytic domain	0.73	49.0	4.36e-01	96.2%	50.0%
1a9xA08	3.40.50.1380	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylglyoxal synthase-like domain	0.71	39.0	4.68e-01	98.1%	79.2%
1zczA01	3.40.50.1380	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylglyoxal synthase-like domain	0.67	40.0	4.09e-01	96.9%	60.3%
2fi1A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.67	39.0	4.42e-01	96.9%	74.8%
1b93B00	3.40.50.1380	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylglyoxal synthase-like domain	0.65	38.0	3.96e-01	99.4%	60.3%
2f00A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.65	31.0	4.01e-01	96.9%	79.5%
7pd2B01	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.63	57.0	4.45e-01	100.0%	73.9%
3h5iA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.63	38.0	4.21e-01	92.5%	74.4%
5cvcA02	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.62	38.0	4.67e-01	91.8%	99.0%
3ndoA00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.62	55.0	4.91e-01	96.2%	95.6%
1dz3A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.62	36.0	4.00e-01	88.1%	71.5%
4wqmA03	3.40.50.80	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module	0.62	40.0	4.33e-01	98.1%	76.7%
3kbbA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.62	38.0	3.96e-01	96.9%	66.0%
1wkvA03	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.61	39.0	4.64e-01	91.8%	99.0%
5t3yA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.61	37.0	4.10e-01	92.5%	75.2%
3gt7A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.61	37.0	4.00e-01	92.5%	71.2%
3khtA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.61	39.0	4.27e-01	93.7%	78.0%
4gvpA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.61	37.0	3.40e-01	93.1%	45.6%
3ed5A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.61	38.0	3.97e-01	98.1%	66.7%
3gl9A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.61	37.0	4.13e-01	93.1%	78.3%
3lufB02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.61	37.0	4.09e-01	90.6%	75.4%
3okpA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.60	52.0	4.88e-01	91.2%	96.3%
1ab5A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.60	36.0	4.02e-01	92.5%	75.2%
3m6mD00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.59	36.0	4.03e-01	92.5%	78.8%
5vegB00	3.40.50.360	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain	0.59	42.0	4.32e-01	90.6%	77.2%
1k68A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.59	40.0	4.26e-01	93.1%	78.6%
3t6kA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.58	35.0	3.96e-01	93.1%	77.0%
3c3mA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.58	34.0	3.82e-01	84.3%	73.2%
2ffiA00	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.58	50.0	4.21e-01	93.7%	94.1%
2zayA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.58	35.0	3.91e-01	92.5%	76.4%
3nbmA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.57	30.0	3.56e-01	90.6%	73.1%
2pq6A01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.57	48.0	4.31e-01	90.6%	97.7%
5i7wA02	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.57	37.0	4.30e-01	93.1%	92.1%
3ilhA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.56	36.0	3.95e-01	93.1%	77.4%
2ejaA00	3.20.20.210	Alpha Beta › Alpha-Beta Barrel › TIM Barrel ›	0.56	48.0	3.83e-01	94.3%	92.6%
5d84A02	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.56	36.0	4.25e-01	74.2%	93.7%
2yvqA00	3.40.50.1380	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylglyoxal synthase-like domain	0.56	40.0	4.34e-01	97.5%	88.1%
2b3zA02	3.40.430.10	Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A	0.55	50.0	4.49e-01	100.0%	83.6%
6bmaA00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.55	49.0	4.26e-01	99.4%	78.0%
1izcA00	3.20.20.60	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains	0.55	49.0	4.02e-01	97.5%	79.9%
2d13A01	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.55	32.0	3.69e-01	97.5%	78.1%
4d9gA02	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.55	39.0	4.41e-01	91.2%	97.5%
2x0dA01	3.40.50.11090	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.55	47.0	4.27e-01	91.2%	89.5%
3k30A03	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.54	39.0	4.20e-01	96.2%	87.2%
1p5jA02	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.54	33.0	4.01e-01	75.5%	99.0%
3getA01	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.54	40.0	3.61e-01	78.0%	61.8%
6yttA02	3.40.50.2030	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.54	39.0	3.84e-01	100.0%	70.0%
4rhiA00	3.40.800.10	Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain	0.53	46.0	3.71e-01	95.0%	78.2%
3elbA01	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.53	33.0	3.54e-01	98.1%	70.8%
3cg4A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.53	38.0	4.17e-01	91.2%	92.9%
3elbA02	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.53	34.0	3.43e-01	98.1%	61.8%
3lk7A03	3.90.190.20	Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain	0.53	42.0	4.53e-01	88.7%	100.0%
1cozA00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.53	33.0	3.65e-01	97.5%	77.8%
3ny7A00	3.30.750.24	Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain	0.52	35.0	3.90e-01	92.5%	89.8%
3ff4A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.52	37.0	4.25e-01	93.1%	98.3%
1d5wA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.52	37.0	4.11e-01	91.8%	95.1%
3cu5B00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.51	36.0	3.93e-01	89.9%	89.1%
2rdmA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.51	36.0	4.04e-01	74.8%	94.4%
4fx5A02	3.40.50.410	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain	0.51	44.0	4.21e-01	93.7%	81.0%
1qzuA00	3.40.50.1950	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like	0.51	38.0	3.83e-01	97.5%	76.9%
1iirA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.51	43.0	3.90e-01	93.1%	86.0%
2l3fA00	3.40.470.10	Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain	0.50	35.0	3.54e-01	70.4%	96.3%
2qs7A00	3.40.1260.10	Alpha Beta › 3-Layer(aba) Sandwich › Hypothetical Protein Ychn; Chain: A, › DsrEFH-like	0.50	41.0	4.43e-01	95.6%	100.0%
4k05A01	3.40.50.12170	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Uncharacterised protein PF07075, DUF1343	0.50	40.0	3.60e-01	86.2%	86.5%

ECOD (65)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3838380	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.90	77.0	6.15e-01	100.0%	50.0%
2387778	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.87	79.0	6.31e-01	100.0%	53.4%
3840123	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.85	77.0	5.97e-01	100.0%	48.1%
3386720	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.83	76.0	6.12e-01	100.0%	53.9%
4325819	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.81	68.0	5.68e-01	100.0%	54.5%
4994179	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.80	68.0	5.80e-01	100.0%	58.7%
4224433	7555.1.1.0 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related	0.79	64.0	5.65e-01	100.0%	60.5%
4946285	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.79	70.0	5.95e-01	100.0%	60.4%
4976142	7562.1.1.2 ↗	a/b three-layered sandwiches › Thiamin pyrophosphokinase, catalytic domain › Thiamin pyrophosphokinase, catalytic domain › Thiamin pyrophosphokinase, catalytic domain › MptE-like	0.78	69.0	5.71e-01	100.0%	56.2%
4978575	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.78	68.0	5.67e-01	100.0%	56.5%
5071857	7562.1.1.2 ↗	a/b three-layered sandwiches › Thiamin pyrophosphokinase, catalytic domain › Thiamin pyrophosphokinase, catalytic domain › Thiamin pyrophosphokinase, catalytic domain › MptE-like	0.78	69.0	5.70e-01	100.0%	55.8%
5016816	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.78	68.0	5.84e-01	100.0%	61.7%
4983584	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.78	67.0	5.65e-01	100.0%	57.4%
5044562	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.77	66.0	5.75e-01	100.0%	61.7%
4038369	7543.1.1.2 ↗	a/b three-layered sandwiches › Methylglyoxal synthase-like › Methylglyoxal synthase-like › Methylglyoxal synthase-like › MGS	0.77	39.0	4.29e-01	98.1%	58.5%
3282990	7555.1.1.0 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related	0.76	62.0	5.65e-01	100.0%	65.9%
4885946	7543.1.1.2 ↗	a/b three-layered sandwiches › Methylglyoxal synthase-like › Methylglyoxal synthase-like › Methylglyoxal synthase-like › MGS	0.76	40.0	4.27e-01	98.1%	57.9%
5037151	7543.1.1.2 ↗	a/b three-layered sandwiches › Methylglyoxal synthase-like › Methylglyoxal synthase-like › Methylglyoxal synthase-like › MGS	0.74	39.0	4.36e-01	97.5%	64.8%
4331040	7543.1.1.2 ↗	a/b three-layered sandwiches › Methylglyoxal synthase-like › Methylglyoxal synthase-like › Methylglyoxal synthase-like › MGS	0.74	39.0	4.13e-01	97.5%	57.1%
3737794	7543.1.1.2 ↗	a/b three-layered sandwiches › Methylglyoxal synthase-like › Methylglyoxal synthase-like › Methylglyoxal synthase-like › MGS	0.73	40.0	4.34e-01	98.1%	63.0%
3839749	7543.1.1.2 ↗	a/b three-layered sandwiches › Methylglyoxal synthase-like › Methylglyoxal synthase-like › Methylglyoxal synthase-like › MGS	0.73	39.0	4.43e-01	98.1%	68.3%
4004626	7555.1.1.4 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › PF27901	0.72	68.0	5.65e-01	100.0%	69.4%
4948746	7555.1.1.2 ↗	a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › MptE-like	0.70	66.0	5.63e-01	100.0%	72.1%
4939778	7586.1.1.1 ↗	a/b three-layered sandwiches › Rossmann-like domain in prismane-like proteins › Rossmann-like domain in prismane-like proteins › Rossmann-like domain in prismane-like proteins › Prismane	0.69	35.0	4.12e-01	98.1%	69.7%
3855778	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.63	38.0	4.05e-01	93.1%	66.2%
4939542	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.62	37.0	4.17e-01	91.8%	76.0%
4479041	2002.1.1.76 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DeoC	0.61	53.0	4.83e-01	95.0%	96.7%
5033898	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.60	37.0	4.10e-01	92.5%	76.0%
3278049	7579.1.1.0 ↗	a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases	0.60	49.0	4.66e-01	93.7%	74.1%
3294106	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.60	36.0	3.90e-01	93.1%	68.9%
4067397	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.60	40.0	4.18e-01	92.5%	73.1%
4927745	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.60	38.0	4.23e-01	93.1%	80.0%
3176212	2003.1.1.65 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_7	0.59	35.0	3.88e-01	98.1%	70.8%
2125712	2007.2.1.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1	0.59	42.0	4.32e-01	90.6%	77.2%
3434103	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.59	36.0	4.01e-01	93.1%	78.3%
138404	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.58	37.0	4.16e-01	91.2%	82.1%
150487	2002.1.1.10 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › IGPS	0.58	51.0	4.49e-01	98.1%	81.4%
4577003	7501.1.1.2 ↗	a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C	0.57	52.0	4.70e-01	98.7%	84.2%
3794894	2002.1.1.67 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Pro_dh	0.57	51.0	3.72e-01	99.4%	91.1%
2632485	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.57	42.0	3.61e-01	76.7%	95.3%
4816241	7501.1.1.2 ↗	a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C	0.56	50.0	4.88e-01	98.7%	87.9%
4663296	7501.1.1.2 ↗	a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C	0.56	50.0	4.54e-01	98.1%	83.2%
3453379	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.56	49.0	4.35e-01	94.3%	90.4%
5043856	247.1.1.1 ↗	a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B	0.56	51.0	4.45e-01	100.0%	89.1%
5016726	7512.1.1.107 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › DUF354	0.55	48.0	4.57e-01	93.1%	87.6%
4181298	601.23.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III	0.55	44.0	3.14e-01	95.6%	30.0%
4319132	2007.1.4.3 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain › NAD_kinase	0.55	34.0	3.82e-01	97.5%	80.0%
4679695	7543.1.1.2 ↗	a/b three-layered sandwiches › Methylglyoxal synthase-like › Methylglyoxal synthase-like › Methylglyoxal synthase-like › MGS	0.54	41.0	4.17e-01	96.2%	80.6%
4949256	7501.1.1.2 ↗	a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C	0.54	49.0	4.43e-01	100.0%	85.9%
2060238	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.52	37.0	4.00e-01	91.2%	85.4%
5082494	7501.1.1.2 ↗	a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C	0.52	47.0	4.25e-01	100.0%	84.1%
5080107	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.52	37.0	4.07e-01	90.6%	90.8%
4951636	247.1.1.11 ↗	a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2	0.52	46.0	3.99e-01	96.2%	91.3%
4183670	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.52	38.0	4.03e-01	91.2%	88.9%
5026943	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.51	43.0	4.32e-01	90.6%	90.9%
3968823	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.51	36.0	3.82e-01	95.6%	83.0%
4065693	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.51	37.0	3.89e-01	90.6%	84.3%
385830	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.51	39.0	4.15e-01	93.1%	92.7%
3978922	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.51	37.0	4.00e-01	91.8%	88.9%
3480304	7577.1.1.7 ↗	a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Cys_Met_Meta_PP	0.51	38.0	3.19e-01	78.0%	55.0%
2840984	2006.1.6.13 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_3	0.51	44.0	4.22e-01	93.7%	81.4%
3838332	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.51	37.0	3.97e-01	91.2%	87.1%
4112959	7512.1.1.1 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT	0.50	42.0	3.54e-01	89.3%	86.8%
3966785	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.50	36.0	3.88e-01	91.2%	87.4%
5039067	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.50	37.0	4.03e-01	91.8%	91.9%

D5 medium residues 666-743

PDB

Domain cluster: representative

CATH (12)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1mhxA00	3.10.20.10	Alpha Beta › Roll › Ubiquitin-like (UB roll) ›	0.62	36.0	3.89e-01	91.0%	67.7%
7wq5A01	3.30.730.10	Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › AP2/ERF domain	0.60	34.0	3.74e-01	89.7%	70.7%
8b4hA01	3.30.420.10	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H	0.58	38.0	3.00e-01	89.7%	32.1%
2k4vA00	3.30.160.370	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064	0.56	35.0	3.09e-01	89.7%	39.2%
5r0dB01	2.60.34.20	Mainly Beta › Sandwich › Substrate Binding Domain Of DNAk; Chain A, domain 1 ›	0.56	32.0	2.65e-01	78.2%	30.1%
2rsmA00	3.30.160.20	Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain ›	0.55	31.0	2.80e-01	89.7%	36.5%
3k44B00	3.30.2450.30	Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold ›	0.55	44.0	3.69e-01	89.7%	72.1%
4udqA02	3.30.410.40	Alpha Beta › 2-Layer Sandwich › Cholesterol Oxidase; domain 2 ›	0.54	39.0	3.12e-01	78.2%	100.0%
2zihC00	1.10.3630.10	Mainly Alpha › Orthogonal Bundle › yeast vps74-n-term truncation variant fold › yeast vps74-n-term truncation variant domain like	0.54	37.0	2.59e-01	73.1%	33.3%
3iq2A00	3.30.1520.10	Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain	0.51	39.0	3.40e-01	83.3%	82.9%
3oqgA00	3.40.1440.50	Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease ›	0.50	35.0	2.76e-01	78.2%	31.8%
2wweA01	3.30.1520.10	Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain	0.50	39.0	3.57e-01	84.6%	87.5%

ECOD (20)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3955895	4232.1.1.1 ↗	few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28	0.68	43.0	4.97e-01	75.6%	90.9%
3933447	2484.1.1.9 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve	0.65	37.0	3.41e-01	89.7%	42.9%
4323754	4232.1.1.1 ↗	few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28	0.63	34.0	4.24e-01	93.6%	87.5%
4342292	4232.1.1.1 ↗	few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28	0.62	37.0	4.28e-01	93.6%	83.6%
3292891	2003.1.5.121 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF1442	0.62	37.0	2.74e-01	71.8%	22.4%
3598294	226.1.1.0 ↗	a+b two layers › POZ domain › POZ domain › POZ domain	0.60	39.0	3.36e-01	84.6%	41.6%
3710894	221.1.1.0 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like	0.59	34.0	3.86e-01	76.9%	77.6%
4096542	4232.1.1.1 ↗	few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28	0.58	36.0	4.21e-01	88.5%	89.1%
3821886	4099.1.1.0 ↗	a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like	0.58	32.0	3.33e-01	76.9%	56.0%
3251342	277.1.1.1 ↗	a+b two layers › PX domain › PX domain › PX domain › PX	0.55	41.0	3.58e-01	79.5%	81.7%
4027507	277.1.1.1 ↗	a+b two layers › PX domain › PX domain › PX domain › PX	0.55	40.0	3.52e-01	78.2%	85.8%
4494590	3223.1.1.1 ↗	beta sandwiches › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › ASC	0.55	43.0	2.64e-01	88.5%	49.4%
4421975	4232.1.1.1 ↗	few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28	0.55	36.0	4.10e-01	88.5%	94.5%
3863194	277.1.1.1 ↗	a+b two layers › PX domain › PX domain › PX domain › PX	0.54	41.0	3.50e-01	83.3%	81.5%
3694002	277.1.1.1 ↗	a+b two layers › PX domain › PX domain › PX domain › PX	0.53	43.0	3.48e-01	93.6%	75.8%
3811535	331.3.1.28 ↗	a+b two layers › TBP-like › Bet v1-like › Bet v1-like › DUF220	0.52	35.0	3.12e-01	70.5%	54.4%
4239635	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.52	30.0	2.42e-01	92.3%	25.5%
3266842	277.1.1.1 ↗	a+b two layers › PX domain › PX domain › PX domain › PX	0.51	39.0	3.38e-01	83.3%	81.6%
3893274	277.1.1.1 ↗	a+b two layers › PX domain › PX domain › PX domain › PX	0.51	39.0	3.21e-01	83.3%	90.0%
3971390	4033.1.1.6 ↗	alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › AidB_N	0.50	40.0	3.23e-01	88.5%	76.2%