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IMGVR_UViG_3300002514_003122-3300002514-JGI25133J35611_100073852

Arc-Vir

IMGVR_UViG_3300002514_003122-3300002514-JGI25133J35611_100073852

Quality

92.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 115-127_257-344
PDB
Domain cluster: representative
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yk4A01 3.30.370.20 Alpha Beta › 2-Layer Sandwich › Barnase; Chain D › 0.64 41.0 4.44e-01 75.2% 79.3%
4mzyA02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.62 51.0 4.36e-01 90.1% 73.2%
1vm8B01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.61 48.0 3.20e-01 85.1% 66.1%
2podA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.60 54.0 4.01e-01 100.0% 71.3%
2r6oA00 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.60 52.0 3.98e-01 100.0% 82.9%
3c8zA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.60 48.0 3.44e-01 89.1% 68.0%
4fixA01 3.90.550.60 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › 0.59 46.0 3.07e-01 87.1% 20.8%
3geeA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 48.0 4.42e-01 90.1% 85.7%
1h3fA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 48.0 3.90e-01 90.1% 73.8%
2gl5A02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.58 51.0 3.77e-01 97.0% 54.1%
3sy8A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 51.0 4.62e-01 97.0% 89.0%
3kp1A01 3.20.20.440 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › D-Lysine 5,6-aminomutase alpha subunit 0.58 51.0 3.43e-01 100.0% 56.2%
2ziuB01 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 51.0 4.49e-01 98.0% 86.6%
2o2zA00 3.40.50.10680 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CofD-like domains 0.57 49.0 3.56e-01 99.0% 99.4%
3rkuA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 50.0 3.74e-01 100.0% 83.6%
2aznA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.56 49.0 3.90e-01 100.0% 45.7%
3ibtA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 49.0 4.06e-01 100.0% 56.5%
2ejbA00 3.40.50.1950 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like 0.56 49.0 4.11e-01 98.0% 94.9%
2khoA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.56 42.0 3.67e-01 80.2% 91.8%
2ixaA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 42.0 3.63e-01 82.2% 58.6%
4xfjB01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.56 43.0 3.67e-01 84.2% 57.8%
2bfwA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 47.0 3.91e-01 98.0% 51.3%
1bifA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 48.0 3.78e-01 94.1% 89.3%
1u3dA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 41.0 3.56e-01 80.2% 52.2%
2o57A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 45.0 3.85e-01 90.1% 63.0%
2gpyB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 45.0 3.67e-01 90.1% 54.7%
1xngA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 43.0 3.33e-01 87.1% 40.5%
1kqpA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 42.0 3.22e-01 87.1% 40.6%
1fs2A00 3.80.10.10 Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor 0.54 42.0 3.15e-01 84.2% 41.7%
1npdB02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 3.91e-01 90.1% 73.8%
2l5oA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.54 46.0 4.03e-01 94.1% 75.3%
1wp0A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.54 45.0 3.90e-01 93.1% 75.0%
4yt2A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 45.0 3.68e-01 96.0% 89.2%
4g0mA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 45.0 4.09e-01 93.1% 90.4%
4g41A00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.53 44.0 3.43e-01 94.1% 88.1%
2mr5A00 3.40.50.11230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 44.0 4.05e-01 98.0% 69.9%
4hlnA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.53 45.0 3.59e-01 98.0% 46.0%
3erwF00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.52 45.0 4.12e-01 94.1% 73.3%
3hczA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.52 44.0 3.96e-01 94.1% 76.9%
1xmxA02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.52 46.0 4.12e-01 100.0% 93.3%
1rhdA01 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.52 44.0 3.84e-01 95.0% 77.6%
3mfqA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.52 44.0 4.03e-01 96.0% 89.6%
1uarA01 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.51 42.0 3.84e-01 94.1% 77.5%
2qxlB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 43.0 4.01e-01 97.0% 76.1%
2b7jB01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.51 42.0 3.68e-01 95.0% 71.3%
5dp2A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 41.0 3.74e-01 90.1% 69.5%
6k6wC01 3.40.50.10710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Metallo-hydrolase/oxidoreductase 0.50 38.0 3.46e-01 83.2% 75.2%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5055800 2002.1.1.29 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DHDPS 0.64 56.0 3.86e-01 98.0% 54.7%
3404837 7585.1.1.0 a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins 0.64 51.0 4.46e-01 87.1% 72.9%
3412401 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.63 52.0 4.37e-01 90.1% 70.6%
5076870 7512.1.1.3 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.62 49.0 4.08e-01 96.0% 47.8%
4941784 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.62 50.0 4.55e-01 87.1% 69.6%
5017820 2002.1.1.173 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › GH123_cat 0.60 52.0 3.76e-01 99.0% 56.5%
3684893 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.59 46.0 3.13e-01 85.1% 22.5%
5070528 2004.1.1.164 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Roc 0.59 51.0 4.27e-01 98.0% 88.6%
4127988 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.59 45.0 4.04e-01 81.2% 96.4%
5050168 2004.1.1.67 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CbiA 0.59 51.0 3.85e-01 100.0% 92.2%
4380807 2484.6.1.1 mixed a+b and a/b › Ribonuclease H-like › Periplasmic domain of ExbD/TolR › Periplasmic domain of ExbD/TolR › ExbD 0.59 41.0 4.42e-01 72.3% 100.0%
3212684 7516.1.1.8 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Galactosyl_T 0.58 46.0 3.34e-01 86.1% 29.3%
3689216 7579.1.1.95 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1, Hydrolase_4 0.58 50.0 3.60e-01 98.0% 88.6%
3276002 2003.4.1.0 a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes 0.58 44.0 3.70e-01 100.0% 46.1%
3622022 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.57 45.0 4.01e-01 87.1% 60.0%
4804156 2005.1.1.12 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1e 0.57 45.0 4.22e-01 87.1% 90.7%
3648474 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 44.0 3.78e-01 86.1% 67.6%
3295953 7512.1.1.50 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_5 0.56 44.0 3.57e-01 85.1% 53.5%
4208424 2002.4.1.1 a/b barrels › TIM beta/alpha-barrel › Nicotinate/Quinolinate PRTase C-terminal domain-like › Nicotinate/Quinolinate PRTase C-terminal domain-like › NAPRTase 0.56 48.0 3.59e-01 96.0% 46.9%
5029640 2005.1.1.11 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.55 43.0 3.48e-01 86.1% 45.6%
3272103 2007.9.1.12 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TRAPPC10_1st 0.55 45.0 4.49e-01 91.1% 95.2%
4025272 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 48.0 3.95e-01 99.0% 95.8%
None 0.55 45.0 3.92e-01 90.1% 67.3%
3967679 2484.6.1.1 mixed a+b and a/b › Ribonuclease H-like › Periplasmic domain of ExbD/TolR › Periplasmic domain of ExbD/TolR › ExbD 0.54 43.0 4.32e-01 85.1% 91.0%
3215949 7590.1.1.9 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › PF29016 0.54 45.0 4.04e-01 90.1% 84.3%
4935626 2007.3.1.6 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA_2 0.54 46.0 3.99e-01 97.0% 92.9%
4060776 2005.1.1.18 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › NAD_synthase 0.54 42.0 3.20e-01 87.1% 43.3%
3728696 7579.1.1.99 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4, Abhydrolase_6 0.54 47.0 3.36e-01 97.0% 88.7%
4070508 2005.1.1.18 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › NAD_synthase 0.54 42.0 3.17e-01 87.1% 43.5%
3702508 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.54 40.0 3.32e-01 80.2% 94.9%
5081823 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.54 47.0 4.26e-01 96.0% 78.5%
3844606 2007.9.1.4 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 0.54 48.0 4.14e-01 100.0% 93.8%
4144736 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.54 40.0 3.86e-01 79.2% 98.3%
4679973 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.54 41.0 3.51e-01 84.2% 96.0%
3278518 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.53 45.0 3.80e-01 94.1% 100.0%
4081882 2485.1.1.45 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_8 0.53 47.0 4.21e-01 99.0% 80.6%
4302118 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.53 46.0 3.88e-01 100.0% 60.0%
4956281 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.53 45.0 3.52e-01 97.0% 88.9%
4928016 2485.1.1.4 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › AhpC-TSA 0.53 43.0 3.98e-01 93.1% 69.2%
4928992 2485.1.1.4 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › AhpC-TSA 0.52 44.0 3.98e-01 94.1% 79.9%
4028018 2007.2.5.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese 0.52 44.0 3.90e-01 94.1% 88.7%
5026943 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 45.0 3.89e-01 100.0% 75.8%
4377806 2003.1.1.29 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › OCD_Mu_crystall 0.52 42.0 3.46e-01 90.1% 52.1%
2554478 2006.1.1.16 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_like,Hydrolase_6 0.52 37.0 4.04e-01 76.2% 93.8%
170031 2485.1.1.4 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › AhpC-TSA 0.51 43.0 3.94e-01 94.1% 71.6%
3815695 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.51 41.0 3.73e-01 90.1% 76.4%
5033473 2007.1.14.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › ZnuA 0.51 43.0 3.67e-01 96.0% 66.5%
3388192 2485.1.1.81 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › TraF 0.50 43.0 3.85e-01 94.1% 69.3%
4928843 300.1.1.0 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.50 43.0 3.84e-01 99.0% 95.5%
D2 high residues 139-249
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF21995.2 best RNR-II_ins_dom 34.4 3.00e-08 82.0% 77.6%
D3 medium residues 1-50
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ogzA02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.59 41.0 2.56e-01 74.0% 23.4%
3cwvA02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.54 37.0 2.77e-01 76.0% 57.0%
3cw9A01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 48.0 3.27e-01 100.0% 74.1%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3654156 7.1.1.0 beta barrels › PDZ domain › PDZ domain › PDZ domain 0.79 54.0 3.55e-01 72.0% 58.3%
3421635 7.1.1.0 beta barrels › PDZ domain › PDZ domain › PDZ domain 0.78 53.0 3.54e-01 72.0% 58.4%
4016123 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.61 44.0 2.62e-01 76.0% 74.9%
D4 medium residues 51-114
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1a0cA00 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.55 47.0 2.91e-01 100.0% 41.4%
D5 medium residues 355-474
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.90 87.0 5.49e-01 100.0% 28.6%
1r1rA02 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.86 81.0 5.18e-01 100.0% 34.5%
2qlcA00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.64 41.0 4.12e-01 90.0% 61.9%
3agrA01 3.30.420.530 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.62 51.0 4.20e-01 90.8% 75.3%
8d88A01 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.61 44.0 3.48e-01 89.2% 35.4%
3q71A00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.61 50.0 4.18e-01 88.3% 71.9%
4l69A02 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.59 54.0 4.72e-01 100.0% 75.6%
3kizA01 3.30.1330.10 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › PurM-like, N-terminal domain 0.58 51.0 4.88e-01 100.0% 83.0%
1q77A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.57 51.0 4.88e-01 96.7% 87.7%
1vk3A03 3.30.1330.10 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › PurM-like, N-terminal domain 0.57 43.0 4.06e-01 100.0% 64.6%
1yd9B00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.57 47.0 4.05e-01 89.2% 77.5%
1qu9A00 3.30.1330.40 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › RutC-like 0.57 42.0 4.19e-01 99.2% 74.0%
2w5fA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.55 46.0 3.29e-01 90.0% 42.1%
3bs4A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 45.0 3.60e-01 90.0% 56.7%
3wqcA02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.55 44.0 3.65e-01 88.3% 50.7%
5ailA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.54 44.0 3.90e-01 88.3% 75.6%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.54 43.0 3.00e-01 85.0% 39.6%
3bypA00 3.30.70.1350 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain 0.54 36.0 4.24e-01 97.5% 100.0%
2mx8A01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.53 38.0 3.95e-01 74.2% 85.0%
2ayaA00 3.30.300.150 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › DNA polymerase III, tau subunit, domain V 0.53 35.0 3.42e-01 91.7% 61.7%
3gemD00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 43.0 3.56e-01 90.8% 49.5%
1zunB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 48.0 4.03e-01 100.0% 80.8%
5macA02 3.20.20.110 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Ribulose bisphosphate carboxylase, large subunit, C-terminal domain 0.52 45.0 3.26e-01 94.2% 80.8%
1r6uA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.52 46.0 3.64e-01 100.0% 48.8%
2rrlA01 3.30.750.140 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › 0.51 38.0 3.93e-01 83.3% 81.7%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4208725 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.92 89.0 5.60e-01 100.0% 24.0%
3275621 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.91 88.0 5.68e-01 100.0% 26.7%
4087732 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.91 88.0 5.55e-01 100.0% 29.5%
5051775 2500.1.1.9 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › RNR-II_ins_dom 0.91 88.0 5.55e-01 100.0% 24.5%
2472944 2500.1.1.2 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.89 84.0 5.50e-01 100.0% 32.2%
3500621 2500.1.1.2 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.86 82.0 5.18e-01 100.0% 32.1%
3958480 2500.1.1.2 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.81 65.0 4.50e-01 84.2% 30.3%
5053026 2500.1.1.5 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › NRDD 0.78 73.0 4.68e-01 100.0% 32.2%
3862376 2004.1.1.122 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IIGP 0.69 45.0 3.10e-01 90.0% 19.8%
5031462 2500.1.1.5 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › NRDD 0.68 62.0 4.03e-01 100.0% 28.6%
3518193 2004.1.1.36 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynamin_N 0.66 42.0 3.23e-01 90.0% 28.5%
3489448 301.2.1.1 a+b three layers › Bacillus chorismate mutase-like › PurM N-terminal domain-like › PurM N-terminal domain-like › AIRS 0.64 38.0 4.44e-01 70.8% 83.5%
3364356 2488.1.1.12 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › Methyltrans_RNA 0.63 52.0 5.20e-01 97.5% 84.0%
3176030 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.63 52.0 5.21e-01 98.3% 87.5%
3576117 2484.1.1.26 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi 0.63 53.0 4.56e-01 91.7% 73.0%
3461776 207.1.1.133 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1, LRR_14 0.62 38.0 3.00e-01 85.0% 29.2%
4959508 327.5.1.3 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C_2 0.61 38.0 4.00e-01 75.0% 68.2%
4927817 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.61 40.0 4.64e-01 96.7% 94.1%
3961973 2002.1.2.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › Hypothetical protein Cthe_0052 0.58 48.0 4.11e-01 90.8% 87.0%
3654114 2484.1.1.26 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi 0.58 48.0 4.01e-01 90.0% 68.6%
4507920 301.2.1.1 a+b three layers › Bacillus chorismate mutase-like › PurM N-terminal domain-like › PurM N-terminal domain-like › AIRS 0.58 43.0 3.92e-01 100.0% 57.6%
4977429 2484.1.1.124 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 0.57 46.0 4.36e-01 85.0% 94.3%
4029083 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 44.0 3.67e-01 85.0% 85.0%
3592244 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 44.0 3.75e-01 84.2% 99.5%
3955549 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.56 44.0 4.44e-01 95.8% 84.2%
2330444 292.2.1.15 a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › PF29923 0.55 38.0 3.75e-01 71.7% 88.5%
3673511 2004.1.1.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.55 45.0 3.82e-01 90.0% 69.3%
5022655 327.11.1.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.55 38.0 3.74e-01 89.2% 65.6%
4557706 2484.1.1.174 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.55 49.0 4.62e-01 98.3% 84.8%
4962375 2484.1.1.49 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N 0.55 45.0 4.39e-01 89.2% 93.3%
3782472 2484.1.1.4 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H 0.54 48.0 4.26e-01 98.3% 96.0%
4931329 2002.1.1.177 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PEPcase_2 0.54 48.0 3.18e-01 100.0% 51.8%
4242803 2488.1.1.12 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › Methyltrans_RNA 0.54 49.0 4.48e-01 100.0% 78.8%
3256710 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.53 45.0 3.52e-01 93.3% 83.8%
4983833 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.53 44.0 4.40e-01 95.0% 87.2%
3882867 2004.1.1.152 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › KAP_NTPase 0.53 44.0 3.52e-01 90.0% 59.2%
4955707 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.53 44.0 4.33e-01 96.7% 84.6%
3852953 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 44.0 3.51e-01 90.0% 66.3%
3807836 2006.1.6.4 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Ku_N 0.52 43.0 3.36e-01 89.2% 72.7%
4945862 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 46.0 4.05e-01 100.0% 89.2%
3497992 2484.1.1.72 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › YqgF 0.52 46.0 4.02e-01 100.0% 77.9%
5023830 2484.1.1.70 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FtsA 0.52 44.0 3.84e-01 95.0% 90.5%
4604367 2005.1.1.3 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.52 44.0 4.30e-01 96.7% 84.4%
4943767 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.51 40.0 4.17e-01 93.3% 88.2%
3512266 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 43.0 3.60e-01 91.7% 70.7%
3736384 315.1.1.6 a+b two layers › Tautomerase/MIF-like › Tautomerase/MIF › Tautomerase/MIF › Tautomerase_3 0.51 44.0 4.08e-01 96.7% 78.1%
3953400 2007.5.1.8 a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › Lipase_GDSL_2 0.51 43.0 3.59e-01 91.7% 83.4%
3214859 3003.1.1.1 a+b complex topology › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › MCM_N 0.50 41.0 4.06e-01 88.3% 91.5%
D6 medium residues 475-542_610-654
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1l1lA03 3.90.1390.10 Alpha Beta › Alpha-Beta Complex › b-12 dependent (class ii) ribonucleotide reductase, chain A, domain 3 › b-12 dependent (class ii) ribonucleotide reductase, chain A, domain 3 0.78 62.0 6.83e-01 82.3% 100.0%
2uv8A06 3.30.70.2490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 29.0 3.69e-01 72.6% 68.7%
2yxlA03 3.30.70.1170 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sun protein; domain 3 0.55 29.0 3.80e-01 78.8% 100.0%
2h1yA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.53 32.0 3.86e-01 92.9% 95.7%
6u9hF02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.52 31.0 3.58e-01 85.8% 84.4%
2f1fA02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.52 31.0 3.61e-01 85.8% 84.6%
1kn6A00 3.30.70.850 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8, pro-domain 0.52 33.0 3.79e-01 83.2% 95.9%
2z30B00 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.52 30.0 3.72e-01 87.6% 100.0%
3im8A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.51 32.0 3.77e-01 88.5% 95.9%
2fgcA03 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.51 30.0 3.48e-01 85.8% 82.9%
1jg5A00 3.30.1410.10 Alpha Beta › 2-Layer Sandwich › Gtp Cyclohydrolase I Feedback Regulatory Protein; Chain: K › GTP cyclohydrolase I feedback regulatory protein GFRP 0.51 30.0 3.42e-01 96.5% 78.3%
1utaA00 3.30.70.1070 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat 0.51 31.0 3.67e-01 85.0% 89.6%
1vi7A02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 29.0 3.43e-01 80.5% 85.9%
4dn9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 36.0 3.87e-01 85.8% 87.6%
1r6vA02 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.50 32.0 3.65e-01 96.5% 92.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5051775 2500.1.1.9 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › RNR-II_ins_dom 0.88 64.0 4.00e-01 74.3% 28.2%
3275621 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.87 69.0 4.40e-01 81.4% 33.3%
4087732 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.85 70.0 4.42e-01 85.8% 32.7%
4208725 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.84 67.0 4.19e-01 82.3% 29.6%
2773959 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 33.0 3.98e-01 82.3% 82.9%
4314745 304.117.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC 0.54 32.0 3.88e-01 85.8% 94.3%
3166959 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.53 34.0 3.94e-01 94.7% 92.5%
4658950 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.52 31.0 3.66e-01 85.8% 88.0%
3989870 304.24.1.2 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › DUF1949 0.52 32.0 3.78e-01 84.1% 92.0%
3217984 10.12.1.0 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.52 31.0 3.38e-01 84.1% 72.2%
64876 304.8.1.7 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ALS_ss_C 0.52 31.0 3.43e-01 85.8% 76.5%
4934658 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.51 32.0 3.75e-01 88.5% 97.1%
3743765 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.51 32.0 3.43e-01 86.7% 74.2%
5031736 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.51 29.0 3.65e-01 85.0% 96.9%
5037704 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.51 31.0 3.71e-01 86.7% 93.3%
5030922 304.24.1.37 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › MCR_C 0.51 28.0 3.41e-01 79.6% 90.8%
5068107 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.50 33.0 3.70e-01 96.5% 88.2%
4107133 304.24.1.1 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C 0.50 31.0 3.63e-01 84.1% 92.0%
D7 medium residues 543-609
PDB