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IMGVR_UViG_3300002821_000004-3300002821-Iso3TCLC_1000013884

Arc-Vir

IMGVR_UViG_3300002821_000004-3300002821-Iso3TCLC_1000013884

Quality

50.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 854-975
PDB
D2 medium residues 170-281
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3s2wG00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 36.0 3.39e-01 87.5% 44.4%
3k3fA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.64 57.0 4.13e-01 100.0% 40.4%
3i09A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 51.0 4.23e-01 88.4% 94.1%
6tmfI00 1.10.455.10 Mainly Alpha › Orthogonal Bundle › Ribosomal Protein S7 › Ribosomal protein S7/S5 0.63 56.0 4.52e-01 99.1% 89.7%
2nq2A00 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.60 46.0 3.42e-01 83.0% 98.4%
4j31A00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 45.0 3.20e-01 87.5% 95.9%
5eowA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 49.0 3.47e-01 97.3% 98.6%
2v0cA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 44.0 3.95e-01 84.8% 98.7%
1ltmA02 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.55 41.0 3.61e-01 79.5% 78.6%
4c5fA02 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.54 46.0 4.04e-01 93.8% 73.8%
5x68A00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 46.0 3.26e-01 94.6% 95.2%
1ileA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.53 43.0 3.64e-01 87.5% 91.1%
4hjzA00 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.51 44.0 3.83e-01 99.1% 70.5%
6lpfA01 1.10.730.20 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › 0.50 44.0 3.89e-01 95.5% 98.2%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4032310 159.1.2.6 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail 0.89 74.0 6.63e-01 100.0% 65.3%
1719256 159.1.2.0 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related 0.72 64.0 5.37e-01 100.0% 68.4%
3941716 159.1.2.6 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail 0.69 56.0 5.40e-01 100.0% 76.9%
4986460 159.1.2.0 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related 0.68 58.0 5.46e-01 100.0% 76.4%
3598304 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.67 46.0 3.71e-01 70.5% 87.9%
4588620 101.1.3.4 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 0.66 32.0 3.52e-01 86.6% 55.6%
4938127 167.1.1.1 alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 0.63 53.0 4.43e-01 92.0% 91.9%
3271854 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.58 45.0 3.99e-01 83.0% 71.8%
4973689 140.1.1.0 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.58 42.0 3.37e-01 74.1% 75.2%
4936999 140.1.1.5 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.55 44.0 3.88e-01 83.9% 96.2%
3672138 611.4.1.0 alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like 0.55 42.0 3.84e-01 82.1% 76.0%
5052743 140.1.1.5 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.54 43.0 3.60e-01 83.9% 84.2%
4512739 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.54 49.0 3.85e-01 100.0% 83.0%
4937234 140.1.1.15 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1g 0.54 41.0 3.29e-01 79.5% 76.8%
4381803 140.1.1.8 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1g,Anticodon_3 0.54 42.0 3.27e-01 82.1% 70.4%
4088604 140.1.1.5 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.54 40.0 3.31e-01 78.6% 83.9%
3340050 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.54 49.0 3.84e-01 100.0% 82.6%
3814259 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.54 48.0 3.76e-01 100.0% 77.6%
5014127 5065.1.1.1 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 0.54 47.0 3.57e-01 97.3% 93.0%
3591771 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.53 39.0 3.49e-01 75.9% 89.3%
None 0.52 46.0 3.87e-01 94.6% 87.0%
3789478 3352.1.1.28 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT+PMT_4TMC 0.52 43.0 2.94e-01 92.9% 77.8%
4679374 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.52 47.0 3.69e-01 100.0% 82.6%
4975476 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.51 36.0 3.26e-01 71.4% 90.0%
3250982 5050.1.1.57 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like, NFD4_C 0.50 45.0 3.04e-01 99.1% 32.6%
4128543 551.1.1.1 alpha arrays › Hsp90 co-chaperone CDC37 middle domain › Hsp90 co-chaperone CDC37 middle domain › Hsp90 co-chaperone CDC37 middle domain › CDC37_M 0.50 42.0 3.72e-01 93.8% 63.2%
D3 medium residues 282-433
PDB
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wvuA01 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.58 46.0 4.66e-01 100.0% 85.8%
2b9rA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 39.0 4.11e-01 90.8% 79.3%
1jfaB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.55 50.0 3.76e-01 96.7% 90.6%
1fx0A03 1.20.150.20 Mainly Alpha › Up-down Bundle › Lysin › ATP synthase alpha/beta chain, C-terminal domain 0.53 38.0 4.12e-01 84.9% 88.4%
2mx8A01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.51 32.0 3.62e-01 80.9% 83.2%
5z7cA01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.50 39.0 3.79e-01 82.9% 96.6%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4030882 159.1.2.6 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail 0.82 77.0 6.81e-01 100.0% 71.4%
3945172 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.72 59.0 5.33e-01 91.4% 63.8%
3421210 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.65 36.0 4.43e-01 89.5% 85.3%
4339612 131.1.1.3 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD 0.53 43.0 3.99e-01 88.2% 96.0%
5049229 3352.1.1.15 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › GT87 0.51 39.0 3.14e-01 79.6% 87.8%
D4 medium residues 597-683
PDB
D5 medium residues 752-806
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.68 50.0 3.55e-01 100.0% 29.4%
1yx3A01 3.30.1420.10 Alpha Beta › 2-Layer Sandwich › Dissimilatory Siroheme-sulfite Reductase; Chain: A; domain 1 › DsrC protein, N-terminal domain 0.61 39.0 4.32e-01 87.3% 87.8%
6zzx601 1.10.3460.10 Mainly Alpha › Orthogonal Bundle › Chlorophyll a-b binding protein › Chlorophyll a/b binding protein domain 0.60 39.0 2.61e-01 81.8% 17.1%
3slzA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.58 39.0 3.14e-01 70.9% 81.6%
6h9dA00 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.55 47.0 3.52e-01 100.0% 49.3%
3kt7A01 2.60.120.620 Mainly Beta › Sandwich › Jelly Rolls › q2cbj1_9rhob like domain 0.55 48.0 3.13e-01 100.0% 23.2%
3b40A02 1.10.287.650 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain 0.54 46.0 4.59e-01 100.0% 98.3%
6e1cA01 1.10.760.10 Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain 0.54 46.0 3.37e-01 100.0% 99.4%
2anvA00 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.54 45.0 3.42e-01 100.0% 46.6%
5afdA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 43.0 2.86e-01 100.0% 26.7%
1azsA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.53 44.0 3.16e-01 100.0% 35.8%
4hfvA02 6.10.280.170 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Substrate of the Dot/Icm secretion system 0.52 45.0 4.21e-01 100.0% 77.5%
4ikbA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.52 42.0 3.28e-01 94.5% 54.3%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 44.0 4.02e-01 98.2% 77.0%
1r7lA00 3.30.2120.10 Alpha Beta › 2-Layer Sandwich › Bacillus phage protein › Bacillus phage protein-like 0.51 36.0 3.02e-01 76.4% 53.4%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3839057 2004.1.1.714 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_13 0.65 55.0 3.55e-01 100.0% 29.6%
5045147 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.63 53.0 3.17e-01 100.0% 12.4%
4074261 101.1.2.88 alpha arrays › HTH › HTH › winged helix domain › Dimerisation 0.62 46.0 3.54e-01 100.0% 32.0%
3955729 150.8.1.7 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PF29644 0.58 49.0 3.56e-01 100.0% 35.2%
3554880 185.1.3.1 alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › GDNF receptor › GDNF 0.57 53.0 4.26e-01 100.0% 58.0%
3930028 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.56 49.0 2.87e-01 100.0% 11.3%
3574038 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.56 48.0 2.83e-01 100.0% 11.2%
4022479 5059.1.1.6 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › CSG2 0.54 44.0 2.78e-01 100.0% 25.8%
3183952 315.1.1.0 a+b two layers › Tautomerase/MIF-like › Tautomerase/MIF › Tautomerase/MIF 0.54 47.0 3.45e-01 100.0% 57.4%
3620425 376.1.1.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.53 38.0 3.19e-01 76.4% 57.1%
1883738 633.6.1.8 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX_C_alpha1 0.53 44.0 3.20e-01 100.0% 74.4%
3260080 376.1.1.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.52 36.0 3.27e-01 74.5% 61.3%
2939128 7524.1.1.3 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › LuxC 0.52 37.0 2.65e-01 100.0% 22.4%
5038823 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.52 43.0 3.99e-01 100.0% 98.7%
4973607 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.52 44.0 2.94e-01 100.0% 27.8%
3690944 101.1.2.88 alpha arrays › HTH › HTH › winged helix domain › Dimerisation 0.52 42.0 3.21e-01 100.0% 37.4%
4981102 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.52 41.0 3.31e-01 94.5% 75.2%
3196924 389.1.1.134 few secondary structure elements › EGF-like › EGF-related › EGF/Laminin › DUF7707 0.51 44.0 3.86e-01 100.0% 68.2%
1192643 3016.1.1.3 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_5 0.51 39.0 3.28e-01 90.9% 49.5%
5083877 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.51 40.0 3.24e-01 100.0% 85.2%
3870810 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 44.0 2.32e-01 100.0% 3.6%
D6 medium residues 976-1044
PDB