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IMGVR_UViG_3300002821_000089-3300002821-Iso3TCLC_100357752
Arc-VirIMGVR_UViG_3300002821_000089-3300002821-Iso3TCLC_100357752
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 34-61_73-218
Domain cluster:
rep: IMGVR_UViG_3300014911_000041-3300014911-Ga0180301_1000169628__D6-181
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2iu5B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.69 | 43.0 | 4.34e-01 | 89.7% | 61.0% |
| 4f4cA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.68 | 59.0 | 3.89e-01 | 93.7% | 72.4% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.66 | 57.0 | 5.32e-01 | 100.0% | 75.3% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 41.0 | 4.51e-01 | 87.4% | 77.9% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.62 | 56.0 | 5.16e-01 | 100.0% | 76.2% |
| 1zk8B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 38.0 | 4.30e-01 | 88.5% | 79.5% |
| 3f1bA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 38.0 | 3.78e-01 | 88.5% | 57.9% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.59 | 34.0 | 4.25e-01 | 72.4% | 95.1% |
| 7e4nA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.59 | 42.0 | 3.58e-01 | 96.0% | 45.2% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.58 | 44.0 | 4.42e-01 | 92.0% | 78.7% |
| 3iqtA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.58 | 30.0 | 3.63e-01 | 92.5% | 74.6% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.57 | 33.0 | 4.06e-01 | 91.4% | 90.7% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.56 | 36.0 | 4.26e-01 | 73.0% | 94.9% |
| 4nn1A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 40.0 | 3.81e-01 | 93.7% | 62.0% |
| 3godB02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.56 | 38.0 | 3.58e-01 | 80.5% | 57.2% |
| 1ek9A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.55 | 42.0 | 3.18e-01 | 78.7% | 98.4% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.54 | 33.0 | 3.45e-01 | 81.0% | 65.2% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.53 | 33.0 | 3.93e-01 | 85.1% | 94.7% |
| 4ys0A02 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.53 | 44.0 | 4.49e-01 | 88.5% | 100.0% |
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.53 | 40.0 | 3.29e-01 | 79.9% | 59.6% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.51 | 39.0 | 3.82e-01 | 78.2% | 81.2% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.51 | 34.0 | 3.43e-01 | 86.8% | 63.6% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 38.0 | 3.29e-01 | 87.9% | 47.9% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.50 | 33.0 | 3.74e-01 | 89.1% | 89.1% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3165030 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.77 | 72.0 | 6.91e-01 | 100.0% | 92.8% |
| 3946757 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.75 | 66.0 | 6.03e-01 | 94.3% | 75.1% |
| 3829174 | 1075.4.1.9 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane | 0.67 | 56.0 | 3.48e-01 | 89.1% | 30.4% |
| 3365375 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.63 | 55.0 | 3.67e-01 | 94.8% | 41.4% |
| 5026216 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.62 | 45.0 | 4.11e-01 | 96.0% | 56.1% |
| 3495555 | 5079.1.1.0 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain | 0.59 | 51.0 | 4.80e-01 | 97.7% | 76.2% |
| 3885225 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.58 | 48.0 | 4.95e-01 | 97.1% | 93.3% |
| 3617361 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.56 | 40.0 | 3.46e-01 | 71.8% | 69.6% |
| 3973556 | 3355.1.1.0 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter | 0.55 | 42.0 | 3.18e-01 | 79.3% | 36.6% |
| 3728017 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 36.0 | 3.22e-01 | 99.4% | 46.5% |
| 3629841 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.52 | 39.0 | 3.58e-01 | 90.8% | 57.6% |
| 4253649 | 601.4.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH | 0.52 | 35.0 | 3.86e-01 | 88.5% | 84.3% |
| 3486791 | 3890.1.1.0 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins | 0.52 | 33.0 | 3.41e-01 | 93.1% | 64.7% |
| 2072359 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.51 | 40.0 | 3.73e-01 | 93.7% | 64.1% |
| 3199780 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 40.0 | 3.83e-01 | 94.3% | 69.8% |
| 4014181 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 41.0 | 3.61e-01 | 86.2% | 62.2% |
D2
medium
residues 222-276
Domain cluster:
rep: MH825712.1__AYD87310.1__SEA_VALENTINIPUFF_6__00006__D248-311
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5v7qZ00 | 3.30.1390.20 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L30/L7 | 0.58 | 47.0 | 4.64e-01 | 98.2% | 100.0% |
| 3hrzC01 | 2.20.210.20 | Mainly Beta › Single Sheet › ubp-family deubiquitinating enzyme fold › | 0.57 | 42.0 | 4.36e-01 | 100.0% | 91.8% |
| 3kl0D01 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.56 | 41.0 | 3.43e-01 | 100.0% | 43.4% |
| 2iteA00 | 2.60.40.1850 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.55 | 44.0 | 3.65e-01 | 100.0% | 96.7% |
| 1wzlA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 38.0 | 3.10e-01 | 78.2% | 94.2% |
| 5mybA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 42.0 | 3.56e-01 | 100.0% | 50.0% |
| 2wraA00 | 2.60.120.400 | Mainly Beta › Sandwich › Jelly Rolls › Calcium-mediated lectin | 0.54 | 46.0 | 3.64e-01 | 100.0% | 86.1% |
| 1j0hA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 37.0 | 2.97e-01 | 74.5% | 94.4% |
| 6spbZ00 | 3.30.1390.20 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L30/L7 | 0.53 | 42.0 | 4.26e-01 | 96.4% | 100.0% |
| 2e8yA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 40.0 | 3.54e-01 | 100.0% | 51.6% |
| 3qugA00 | 2.60.40.1850 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.53 | 43.0 | 3.60e-01 | 100.0% | 94.7% |
| 2h6oA03 | 2.60.40.2820 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.52 | 42.0 | 3.55e-01 | 100.0% | 62.7% |
| 7bi2A02 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.52 | 42.0 | 3.41e-01 | 100.0% | 97.0% |
| 3kopA00 | 2.40.100.20 | Mainly Beta › Beta Barrel › Cyclophilin › | 0.51 | 40.0 | 3.08e-01 | 96.4% | 93.0% |
| 3sz6A00 | 2.60.40.1850 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 41.0 | 3.37e-01 | 96.4% | 94.0% |
| 4lsdF00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 39.0 | 3.34e-01 | 100.0% | 50.0% |
| 4kq7A01 | 2.60.120.1390 | Mainly Beta › Sandwich › Jelly Rolls › Protein of unknown function DUF2961 | 0.50 | 39.0 | 3.05e-01 | 100.0% | 63.0% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3964369 | 6108.1.1.8 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Phage_Mu_F | 0.95 | 90.0 | 5.58e-01 | 100.0% | 22.0% |
| 5057448 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.63 | 44.0 | 3.27e-01 | 100.0% | 28.3% |
| 3223531 | 10.32.1.69 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › LAMININ_IV_B | 0.59 | 49.0 | 3.39e-01 | 100.0% | 27.7% |
| 3212203 | 10.4.1.20 ↗ | beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain › DUF7592 | 0.59 | 50.0 | 4.03e-01 | 100.0% | 67.8% |
| 3932867 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.55 | 38.0 | 3.16e-01 | 76.4% | 100.0% |
| 1402 | 11.1.1.46 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Alpha-amylase_N | 0.54 | 38.0 | 3.11e-01 | 78.2% | 95.0% |
| 3592172 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.54 | 45.0 | 3.43e-01 | 100.0% | 62.7% |
| 4047726 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.54 | 43.0 | 3.98e-01 | 98.2% | 80.0% |
| 3257190 | 10.12.1.101 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › JmjC, Cupin_8 | 0.54 | 45.0 | 2.89e-01 | 100.0% | 31.7% |
| 4994275 | 205.1.1.1 ↗ | a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4 | 0.54 | 42.0 | 3.85e-01 | 94.5% | 100.0% |
| 4238718 | 11.1.1.457 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › FixH | 0.53 | 42.0 | 3.32e-01 | 100.0% | 39.2% |
| 4882965 | 10.2.1.1 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Rhv | 0.53 | 43.0 | 3.34e-01 | 100.0% | 66.7% |
| 3394333 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 38.0 | 3.06e-01 | 83.6% | 98.5% |
| 3319355 | 11.2.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain | 0.52 | 40.0 | 3.43e-01 | 94.5% | 97.3% |
| 4030574 | 929.1.1.0 ↗ | beta duplicates or obligate multimers › Resistin › Resistin › Resistin | 0.52 | 41.0 | 3.71e-01 | 100.0% | 63.1% |
| 3008273 | 11.1.1.72 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › NEAT | 0.51 | 39.0 | 3.20e-01 | 96.4% | 82.1% |
| 3720340 | 11.1.1.150 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Velvet | 0.50 | 43.0 | 3.08e-01 | 100.0% | 36.9% |