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IMGVR_UViG_3300003492_000010-3300003492-JGI26245J51145_10012644

Arc-Vir

IMGVR_UViG_3300003492_000010-3300003492-JGI26245J51145_10012644

Quality

81.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 12-225
PDB
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vpgA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 45.0 5.31e-01 87.4% 100.0%
2zskA02 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.64 34.0 4.67e-01 86.0% 100.0%
4bgvA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.64 44.0 5.12e-01 94.9% 99.3%
6feaB01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.60 40.0 4.67e-01 93.9% 96.6%
1lu4A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.55 24.0 2.94e-01 98.6% 59.7%
1bdbA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 49.0 4.54e-01 98.1% 92.1%
5xtfA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 48.0 4.72e-01 96.7% 98.2%
2yhaA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 37.0 3.62e-01 89.3% 63.8%
1xo1A02 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.53 34.0 3.82e-01 90.2% 83.6%
3u37A02 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.53 44.0 4.26e-01 88.8% 96.8%
2w9xA02 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.53 43.0 4.29e-01 86.4% 93.8%
2q3fA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 40.0 4.36e-01 86.0% 94.4%
5ig2A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 47.0 4.36e-01 99.5% 92.8%
3czpB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 44.0 4.49e-01 91.1% 91.5%
2btoA01 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.52 44.0 4.18e-01 92.1% 100.0%
1g66A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 42.0 4.35e-01 96.3% 88.9%
3cb2B01 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.51 44.0 4.11e-01 91.6% 100.0%
3czpA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 4.25e-01 92.5% 92.1%
3hc7A01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 41.0 4.32e-01 96.3% 94.2%
1yzyA02 3.40.980.20 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › Four-carbon acid sugar kinase, nucleotide binding domain 0.51 38.0 4.12e-01 99.5% 92.7%
3czqC00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 46.0 4.17e-01 97.7% 86.3%
6jtdA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.51 42.0 3.92e-01 87.9% 94.4%
4q9aA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.50 42.0 4.23e-01 88.8% 97.3%
3emzA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.50 42.0 3.65e-01 93.5% 57.4%
7wjlA01 3.40.800.20 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain 0.50 46.0 3.62e-01 99.5% 96.0%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3715277 7514.1.1.0 a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain 0.66 31.0 4.35e-01 89.3% 92.0%
4235371 4126.1.1.6 a/b three-layered sandwiches › beta-carbonic anhydrase-like › beta-carbonic anhydrase › beta-carbonic anhydrase › DabA 0.60 40.0 3.88e-01 98.1% 59.6%
None 0.60 41.0 4.18e-01 86.4% 69.3%
3701198 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 48.0 4.51e-01 86.4% 92.3%
3586624 7590.1.1.6 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › ArgoMid 0.58 36.0 4.06e-01 91.1% 78.8%
4097535 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.56 33.0 4.15e-01 85.5% 96.2%
3969989 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.54 39.0 4.31e-01 96.7% 93.5%
3509121 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.53 42.0 3.94e-01 82.7% 89.8%
4012677 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.53 42.0 4.32e-01 96.3% 87.2%
4017429 7579.1.1.11 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Cutinase 0.52 43.0 4.37e-01 96.3% 86.5%
5042343 2003.1.6.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like › Tubulin 0.52 40.0 4.16e-01 95.8% 86.7%
5001966 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.52 46.0 4.34e-01 95.8% 90.4%
3838039 2488.1.1.12 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › Methyltrans_RNA 0.52 35.0 3.97e-01 96.3% 92.3%
3459076 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.52 47.0 4.43e-01 97.2% 98.8%
5039355 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.51 46.0 4.54e-01 95.8% 99.1%
1233469 2004.1.1.109 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PPK2 0.51 44.0 4.23e-01 92.5% 91.0%
5075852 7512.1.1.8 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Epimerase_2 0.51 41.0 3.95e-01 96.7% 74.6%
3926566 2006.1.6.5 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Tfb4 0.51 42.0 4.25e-01 95.8% 87.9%
3590857 2002.1.1.12 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_1 0.51 45.0 3.49e-01 97.7% 68.3%
4940494 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.50 45.0 4.32e-01 96.7% 98.0%
3962207 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.50 41.0 4.15e-01 85.0% 88.1%
3324679 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.50 44.0 4.19e-01 95.8% 95.0%
4979707 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.50 41.0 3.93e-01 85.5% 88.5%
3613387 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.50 41.0 3.97e-01 87.9% 88.7%
4021811 2004.1.1.168 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRPRB 0.50 40.0 3.64e-01 85.0% 97.0%
D2 high residues 292-384
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.72 51.0 5.03e-01 94.6% 70.1%
1aisB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.70 49.0 4.91e-01 94.6% 70.2%
2ivxB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.69 46.0 4.33e-01 98.9% 55.7%
1zp2A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.69 54.0 5.13e-01 87.1% 69.6%
1x42A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.68 48.0 5.10e-01 93.5% 83.1%
3h4cA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.68 51.0 5.08e-01 81.7% 77.1%
1vinA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.68 47.0 4.15e-01 73.1% 88.5%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.65 46.0 5.02e-01 77.4% 90.7%
4rocA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.65 49.0 4.75e-01 92.5% 71.8%
2px0A01 1.20.120.1380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar FlhF biosynthesis protein, N domain 0.64 47.0 5.18e-01 97.8% 97.3%
5xs2B02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.63 51.0 4.53e-01 87.1% 67.4%
1c9bA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.62 50.0 4.78e-01 86.0% 100.0%
6hxlB01 1.10.230.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 0.57 40.0 3.68e-01 72.0% 57.9%
3nz4B03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.57 45.0 4.36e-01 100.0% 76.0%
2z15A00 3.90.640.90 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › Anti-proliferative protein, N-terminal domain 0.56 47.0 4.37e-01 94.6% 73.1%
2fh0A00 1.10.8.140 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PDCD5, DNA-binding domain 0.55 40.0 4.20e-01 81.7% 88.9%
2qgnA02 1.10.287.890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain 0.54 33.0 3.51e-01 80.6% 69.5%
1k32A03 3.30.750.44 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › 0.53 35.0 3.85e-01 93.5% 86.1%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.53 41.0 4.27e-01 96.8% 90.9%
1e91A00 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.53 35.0 3.66e-01 80.6% 74.1%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4610257 6130.1.1.0 alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain 0.70 46.0 5.27e-01 80.6% 96.9%
5043732 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.69 45.0 5.15e-01 94.6% 88.6%
3360739 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.67 49.0 5.25e-01 77.4% 91.3%
5078898 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.66 50.0 4.79e-01 94.6% 69.1%
1276701 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.65 55.0 4.91e-01 91.4% 65.4%
5050370 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.65 54.0 4.17e-01 91.4% 40.5%
3549313 101.1.10.17 alpha arrays › HTH › HTH › Cyclin-like › CycT2-like_C 0.63 46.0 4.08e-01 97.8% 52.6%
4224947 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.62 45.0 4.37e-01 76.3% 79.0%
5009804 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.62 50.0 5.03e-01 87.1% 84.2%
3512178 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.62 46.0 3.35e-01 77.4% 87.2%
5000181 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.61 49.0 4.67e-01 94.6% 74.5%
3626373 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.60 44.0 4.46e-01 94.6% 76.8%
3781613 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.59 44.0 3.54e-01 79.6% 55.8%
3709879 181.1.1.0 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.59 43.0 4.67e-01 98.9% 96.0%
2741727 101.1.10.14 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C_2 0.58 41.0 4.46e-01 95.7% 90.8%
4379647 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.57 47.0 3.94e-01 93.5% 50.6%
3190824 166.1.1.0 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C 0.57 43.0 4.72e-01 94.6% 100.0%
5073389 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.57 49.0 4.32e-01 95.7% 77.9%
4017306 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.57 45.0 4.78e-01 92.5% 100.0%
3463994 148.1.3.365 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Tcp11 0.55 44.0 3.37e-01 94.6% 35.3%
4957090 103.2.1.2 alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.55 47.0 4.69e-01 95.7% 92.6%
3641850 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.55 45.0 3.89e-01 89.2% 63.4%
4954771 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.54 45.0 3.82e-01 97.8% 84.7%
4144086 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.53 38.0 3.81e-01 77.4% 78.0%
3332131 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.53 45.0 3.66e-01 93.5% 92.8%
3455253 5073.1.1.7 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › PhoLip_ATPase_C 0.52 43.0 3.13e-01 93.5% 78.3%
3253035 2485.1.1.51 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_14 0.52 46.0 3.24e-01 97.8% 42.8%
5059724 186.1.1.4 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_4 0.51 39.0 3.95e-01 93.5% 80.0%
5081699 186.1.1.4 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_4 0.51 39.0 3.98e-01 93.5% 82.2%
D3 high residues 1000-1044_1062-1113
PDB
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1c3kA00 2.100.10.30 Mainly Beta › Aligned Prism › Vitelline Membrane Outer Layer Protein I, subunit A › Jacalin-like lectin domain 0.57 39.0 3.46e-01 70.1% 97.2%
4k7zA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.57 42.0 3.27e-01 79.4% 94.2%
4ntcA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 40.0 3.18e-01 74.2% 82.6%
3h8lA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 41.0 3.24e-01 78.4% 88.3%
3nixB00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 47.0 3.21e-01 99.0% 95.5%
4dapA01 2.40.50.580 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.55 37.0 4.06e-01 70.1% 100.0%
1hyuA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 39.0 3.18e-01 74.2% 87.4%
2vouB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 40.0 3.04e-01 79.4% 94.6%
5x68A00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 39.0 2.72e-01 78.4% 91.8%
4b1bA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 40.0 2.68e-01 82.5% 94.5%
4oonA03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 36.0 3.51e-01 70.1% 99.0%
3udfA03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 36.0 3.66e-01 70.1% 98.9%
1t6lA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.52 38.0 2.86e-01 75.3% 89.6%
3aqgB00 2.100.10.30 Mainly Beta › Aligned Prism › Vitelline Membrane Outer Layer Protein I, subunit A › Jacalin-like lectin domain 0.52 35.0 3.16e-01 70.1% 93.5%
4hb9A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 38.0 2.60e-01 78.4% 93.1%
3bwsA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 37.0 2.64e-01 77.3% 98.5%
1y13A00 3.30.479.10 Alpha Beta › 2-Layer Sandwich › Tetrahydropterin Synthase; Chain A › 6-pyruvoyl tetrahydropterin synthase/QueD 0.50 37.0 3.13e-01 77.3% 77.3%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3802091 4294.1.1.0 few secondary structure elements › Trm112p-like › Trm112p-like › Trm112p-like 0.58 41.0 3.52e-01 72.2% 84.1%
3963171 2003.1.2.24 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 0.57 43.0 2.90e-01 79.4% 83.8%
4534120 2.6.1.0 beta barrels › OB-fold › Staphylococcal nuclease › Staphylococcal nuclease 0.57 41.0 3.19e-01 76.3% 73.0%
3422830 76.1.1.2 beta duplicates or obligate multimers › beta-Prism I › beta-Prism I › beta-Prism I › Jacalin 0.57 39.0 3.30e-01 70.1% 86.9%
2879361 76.1.1.0 beta duplicates or obligate multimers › beta-Prism I › beta-Prism I › beta-Prism I 0.56 38.0 3.27e-01 70.1% 83.4%
3974613 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.55 38.0 4.12e-01 70.1% 100.0%
4494852 4954.1.1.1 a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 0.55 47.0 3.04e-01 93.8% 43.4%
3590203 2.1.1.83 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SfsA_N 0.54 38.0 4.11e-01 72.2% 100.0%
4356401 2.1.1.83 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SfsA_N 0.53 39.0 4.07e-01 77.3% 100.0%
3610035 2.1.1.70 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Prot_ATP_ID_OB_C 0.53 36.0 3.34e-01 70.1% 55.8%
4187258 2003.1.2.16 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3,NAD_binding_8 0.53 44.0 3.15e-01 94.8% 88.3%
D4 high residues 1114-1283
PDB
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4tkoB02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.77 31.0 5.12e-01 93.5% 100.0%
3n6rA04 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.75 32.0 5.05e-01 91.8% 100.0%
3lnnA03 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.74 33.0 5.02e-01 92.4% 100.0%
3fmcA02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.73 33.0 5.03e-01 92.9% 100.0%
1z6hA00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.73 32.0 4.85e-01 92.4% 97.2%
2ejmA01 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.72 31.0 4.77e-01 91.2% 100.0%
5ze9A03 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.71 28.0 4.43e-01 90.6% 91.4%
5bn3A03 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.70 27.0 4.37e-01 89.4% 93.8%
1k8mA00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.67 34.0 4.57e-01 95.3% 93.1%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.65 60.0 5.95e-01 95.9% 100.0%
2pmzB07 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.63 41.0 4.77e-01 97.6% 89.5%
2a6hC06 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.59 45.0 5.06e-01 97.6% 100.0%
4xvoA01 2.60.40.3710 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 31.0 4.11e-01 87.1% 96.6%
1vk3A02 3.30.1330.10 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › PurM-like, N-terminal domain 0.56 34.0 3.83e-01 97.6% 75.6%
3gtzA00 3.30.1330.40 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › RutC-like 0.54 32.0 3.78e-01 94.7% 84.3%
1xxaC00 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.54 25.0 3.59e-01 84.7% 98.6%
5l16A01 3.30.1330.10 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › PurM-like, N-terminal domain 0.54 34.0 3.96e-01 98.2% 87.8%
4nq3A01 3.30.1330.170 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Cyanuric acid hydrolase/Barbiturase, RU A 0.53 31.0 3.98e-01 95.9% 100.0%
1cliB01 3.30.1330.10 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › PurM-like, N-terminal domain 0.50 34.0 3.58e-01 97.6% 75.3%
1p1dA02 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.50 28.0 3.63e-01 95.9% 96.8%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4060952 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.83 38.0 5.70e-01 97.6% 100.0%
5038608 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.78 37.0 5.47e-01 98.2% 100.0%
3941959 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.77 35.0 5.26e-01 95.9% 98.7%
3968908 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.77 34.0 4.77e-01 94.7% 82.2%
4059260 325.1.7.21 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › BSH_RND 0.76 35.0 5.28e-01 94.7% 100.0%
4405980 325.1.7.21 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › BSH_RND 0.76 33.0 5.11e-01 92.9% 100.0%
4142586 325.1.7.21 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › BSH_RND 0.75 36.0 5.29e-01 95.3% 100.0%
3279753 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.75 35.0 4.83e-01 94.7% 88.2%
4944550 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.75 34.0 5.13e-01 94.7% 100.0%
3942958 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.73 37.0 4.67e-01 97.6% 79.0%
4032675 325.1.7.52 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25997 0.73 36.0 5.11e-01 95.3% 100.0%
3257342 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.72 35.0 5.10e-01 95.3% 100.0%
3465888 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.72 36.0 5.15e-01 97.1% 98.8%
3632665 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.71 36.0 5.09e-01 97.1% 98.8%
None 0.71 35.0 5.03e-01 95.9% 100.0%
3282764 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.71 34.0 5.01e-01 94.7% 100.0%
3973436 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.71 34.0 5.01e-01 94.7% 100.0%
3704784 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.71 35.0 4.96e-01 95.9% 96.5%
3840018 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.71 31.0 4.76e-01 93.5% 100.0%
3600078 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.71 35.0 4.93e-01 95.9% 96.5%
3720564 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.70 31.0 4.69e-01 92.4% 100.0%
4094284 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.70 34.0 4.61e-01 94.1% 87.8%
3255476 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.69 35.0 4.76e-01 95.3% 92.2%
3943046 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.69 34.0 4.66e-01 95.3% 90.0%
3479354 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.69 32.0 4.48e-01 93.5% 88.2%
3195628 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.69 34.0 4.81e-01 95.9% 96.4%
4962912 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.69 33.0 4.68e-01 94.1% 92.9%
5073751 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.69 33.0 4.67e-01 94.1% 92.9%
3438062 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.69 33.0 4.39e-01 94.1% 83.2%
3968779 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.68 35.0 4.93e-01 94.7% 100.0%
4558555 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.68 34.0 4.35e-01 94.7% 81.0%
4996169 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.68 33.0 4.73e-01 94.1% 98.8%
3481286 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.68 33.0 4.41e-01 94.1% 84.2%
5011821 325.1.7.1 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Biotin_lipoyl 0.67 31.0 4.65e-01 90.0% 100.0%
3917433 325.1.7.23 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › BSH_Fcp1 0.67 35.0 4.56e-01 97.1% 88.0%
4654615 325.1.7.2 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.67 62.0 5.53e-01 97.6% 100.0%
4255464 325.1.7.2 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.66 61.0 5.31e-01 97.1% 99.6%
4366177 325.1.7.2 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.66 61.0 5.44e-01 97.6% 100.0%
4886404 4042.1.1.1 a+b complex topology › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6 0.65 59.0 5.35e-01 94.7% 100.0%
3730893 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.61 35.0 4.56e-01 94.1% 100.0%
3782159 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.60 34.0 4.51e-01 93.5% 100.0%
4014355 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.60 31.0 4.29e-01 90.6% 100.0%
1503076 325.1.7.21 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › BSH_RND 0.59 36.0 4.48e-01 94.1% 95.4%
5011645 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.59 26.0 3.74e-01 84.1% 89.3%
4237151 306.6.1.2 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › FlgI 0.58 28.0 3.83e-01 85.9% 92.5%
4634310 306.6.1.2 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › FlgI 0.58 28.0 3.78e-01 86.5% 89.4%
4392066 306.6.1.2 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › FlgI 0.58 27.0 3.81e-01 85.9% 96.0%
4099047 306.6.1.2 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › FlgI 0.58 28.0 3.83e-01 87.1% 97.3%
3404406 325.1.7.23 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › BSH_Fcp1 0.58 33.0 4.03e-01 95.9% 84.3%
3174542 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.57 35.0 4.01e-01 95.3% 80.0%
4069281 325.1.7.2 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.57 51.0 5.25e-01 98.2% 100.0%
4513514 325.1.7.2 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.56 40.0 4.76e-01 94.1% 100.0%
3792089 325.1.7.2 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.56 42.0 4.76e-01 97.6% 97.8%
3634241 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.56 27.0 3.91e-01 88.2% 100.0%
4276027 306.6.1.2 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › FlgI 0.55 28.0 3.72e-01 83.5% 97.5%
3491434 325.1.7.2 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.55 41.0 4.68e-01 95.9% 100.0%
3737341 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.54 34.0 3.90e-01 94.1% 82.3%
5009431 301.2.1.1 a+b three layers › Bacillus chorismate mutase-like › PurM N-terminal domain-like › PurM N-terminal domain-like › AIRS 0.53 33.0 3.56e-01 97.6% 71.3%
D5 medium residues 446-509
PDB
Domain cluster: representative
CATH (72)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gaiA03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.78 59.0 4.68e-01 92.2% 41.5%
4cgyA03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.76 55.0 4.33e-01 92.2% 38.3%
3obaA05 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.72 51.0 3.28e-01 87.5% 16.4%
2rkcA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.71 50.0 3.05e-01 96.9% 11.8%
5uj1A03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.70 54.0 3.99e-01 93.8% 31.6%
2b1xB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.69 47.0 3.49e-01 71.9% 30.5%
2vsmA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.68 48.0 2.94e-01 96.9% 11.6%
3volA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.67 49.0 3.82e-01 78.1% 89.1%
6toaF01 3.30.2000.30 Alpha Beta › 2-Layer Sandwich › STM4215-like › 0.67 46.0 3.68e-01 71.9% 82.3%
2vqeE01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.67 45.0 4.56e-01 70.3% 71.9%
3kojB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.67 46.0 4.12e-01 71.9% 53.3%
4z9cB00 2.40.50.110 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.66 49.0 4.03e-01 98.4% 43.5%
1sr9A02 3.30.160.270 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Alpha-isopropylmalate synthase LeuA, regulatory domain 0.66 45.0 3.35e-01 73.4% 27.4%
4gn2A00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.66 47.0 3.21e-01 75.0% 20.8%
2gjvA00 3.30.2000.10 Alpha Beta › 2-Layer Sandwich › STM4215-like › Phage tail protein-like 0.66 47.0 3.74e-01 76.6% 83.1%
3fzxA00 2.40.360.20 Mainly Beta › Beta Barrel › YmcC-like fold › 0.66 46.0 3.22e-01 73.4% 24.5%
1of5B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.66 46.0 3.68e-01 73.4% 36.7%
3gwrB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.66 47.0 3.76e-01 100.0% 38.6%
2nlkA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.65 49.0 3.28e-01 93.8% 20.0%
3ejvA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.65 46.0 3.39e-01 73.4% 40.3%
1pfsA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.64 44.0 4.13e-01 71.9% 57.7%
6rtqA00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.64 45.0 3.62e-01 73.4% 36.8%
1jzdC00 2.60.40.1250 Mainly Beta › Sandwich › Immunoglobulin-like › Thiol:disulfide interchange protein DsbD, N-terminal domain 0.64 48.0 3.96e-01 81.2% 75.4%
2xzmE01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.63 43.0 3.58e-01 70.3% 47.4%
1y8cA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.63 40.0 4.19e-01 79.7% 68.3%
3bf2A00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.63 48.0 3.95e-01 84.4% 76.8%
5jp0A03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 55.0 4.42e-01 96.9% 100.0%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.63 54.0 4.03e-01 95.3% 49.4%
3upuA03 2.30.30.780 Mainly Beta › Roll › SH3 type barrels. › 0.62 49.0 3.96e-01 89.1% 48.9%
1jz7A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 45.0 3.76e-01 78.1% 71.3%
3dm8A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.62 42.0 3.31e-01 71.9% 34.8%
4e3eA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.62 46.0 2.91e-01 81.2% 37.0%
1cyyA02 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.62 44.0 3.64e-01 92.2% 40.0%
4kghA00 3.15.10.10 Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Bactericidal permeability-increasing protein; domain 1 0.61 50.0 3.66e-01 93.8% 70.5%
3e99A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.61 42.0 3.30e-01 73.4% 33.1%
7pkwA01 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.61 41.0 3.57e-01 73.4% 42.7%
1s5aB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 41.0 3.21e-01 71.9% 66.4%
1wnhA01 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 46.0 4.00e-01 87.5% 53.0%
2r4iA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 42.0 3.44e-01 73.4% 38.2%
6gp1A00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.60 41.0 4.13e-01 82.8% 70.8%
4j8tA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 41.0 3.33e-01 71.9% 37.5%
2gtlN02 2.40.128.620 Mainly Beta › Beta Barrel › Lipocalin › 0.59 40.0 3.04e-01 71.9% 29.4%
1uliB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 41.0 3.06e-01 73.4% 28.8%
2g2sA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.59 40.0 4.04e-01 82.8% 70.3%
1y1uA02 2.60.40.630 Mainly Beta › Sandwich › Immunoglobulin-like › STAT transcription factor, DNA-binding domain 0.59 42.0 3.49e-01 79.7% 79.2%
3fhwA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 39.0 3.51e-01 71.9% 52.5%
2k0rA00 2.60.40.1250 Mainly Beta › Sandwich › Immunoglobulin-like › Thiol:disulfide interchange protein DsbD, N-terminal domain 0.58 40.0 3.27e-01 73.4% 68.0%
3bb9B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.58 44.0 3.55e-01 100.0% 42.4%
1gyvA00 2.60.40.1230 Mainly Beta › Sandwich › Immunoglobulin-like › Gamma-adaptin ear (GAE) domain 0.57 40.0 3.43e-01 78.1% 65.0%
1uisA00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.57 39.0 2.83e-01 96.9% 21.4%
1q42A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 39.0 3.06e-01 75.0% 39.6%
2q2bA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.56 46.0 3.66e-01 93.8% 87.2%
3robA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 42.0 3.41e-01 100.0% 40.5%
1vp2A00 3.90.950.10 Alpha Beta › Alpha-Beta Complex › Maf protein › 0.56 47.0 3.53e-01 100.0% 86.8%
2amhA00 3.90.950.10 Alpha Beta › Alpha-Beta Complex › Maf protein › 0.56 44.0 3.19e-01 87.5% 74.9%
3h4zB03 3.15.10.50 Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › 0.56 48.0 3.50e-01 100.0% 73.8%
4iykA02 2.60.40.2060 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 46.0 3.82e-01 93.8% 70.3%
1pn2B01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.55 42.0 3.25e-01 82.8% 86.5%
5optY00 3.30.70.3370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 43.0 3.61e-01 90.6% 69.9%
1q6wG00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.55 40.0 3.17e-01 81.2% 87.2%
2w4yA00 2.40.160.220 Mainly Beta › Beta Barrel › Porin › 0.54 44.0 3.58e-01 90.6% 59.0%
2bi0A01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.54 46.0 3.55e-01 98.4% 86.3%
1tzzB01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.53 45.0 3.67e-01 95.3% 81.5%
3uoaB02 2.60.40.3360 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 42.0 3.44e-01 93.8% 68.4%
2rfrA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 38.0 2.99e-01 100.0% 33.8%
6m9yA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.52 35.0 3.62e-01 82.8% 78.9%
3soyA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 43.0 3.40e-01 93.8% 42.3%
4inaA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.52 44.0 3.21e-01 100.0% 93.4%
2kxgA00 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 37.0 3.35e-01 98.4% 52.6%
4l8hB00 3.30.380.10 Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein 0.51 44.0 3.62e-01 98.4% 67.5%
1qs8A01 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.51 37.0 2.84e-01 90.6% 29.7%
4p2iA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.51 43.0 3.60e-01 98.4% 66.7%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3212332 243.1.1.85 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF26531 0.80 58.0 4.53e-01 76.6% 40.0%
4268775 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.79 54.0 4.23e-01 73.4% 36.0%
5003644 264.2.1.1 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.79 58.0 4.60e-01 93.8% 40.0%
4640527 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.78 53.0 4.17e-01 73.4% 36.0%
3230100 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.78 55.0 5.85e-01 82.8% 85.5%
3996695 3256.1.1.0 a+b two layers › DUF2233 N-terminal domain › DUF2233 N-terminal domain › DUF2233 N-terminal domain 0.78 56.0 6.04e-01 95.3% 89.1%
4542063 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.77 51.0 4.05e-01 73.4% 35.2%
4609098 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.76 50.0 3.83e-01 73.4% 31.9%
4269457 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.76 51.0 3.95e-01 73.4% 33.6%
4289288 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.76 51.0 4.02e-01 73.4% 35.2%
4393122 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.76 50.0 3.89e-01 73.4% 34.4%
4579550 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.76 49.0 3.83e-01 73.4% 33.1%
4591470 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.75 55.0 4.18e-01 93.8% 33.3%
3965319 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.75 49.0 3.96e-01 73.4% 37.4%
4124320 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.75 49.0 3.80e-01 73.4% 33.1%
4228218 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.75 49.0 3.79e-01 73.4% 32.3%
3685150 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.75 51.0 3.67e-01 73.4% 27.3%
4570530 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.75 49.0 4.10e-01 73.4% 41.3%
5037261 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.74 55.0 4.13e-01 96.9% 32.9%
3996069 11.1.1.14 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 0.74 56.0 4.72e-01 81.2% 70.5%
5004264 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.74 50.0 3.95e-01 73.4% 36.6%
4089593 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.73 48.0 3.74e-01 73.4% 33.1%
4240105 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.73 48.0 3.91e-01 73.4% 37.4%
3519929 243.1.1.2 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 0.73 50.0 3.99e-01 71.9% 37.7%
5036880 330.1.1.35 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › LeuA_dimer 0.73 50.0 4.84e-01 73.4% 64.3%
5013672 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.73 51.0 5.15e-01 73.4% 75.4%
4954798 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.73 49.0 3.85e-01 73.4% 35.8%
4977218 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.72 52.0 3.30e-01 100.0% 14.5%
4096366 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.70 49.0 3.90e-01 73.4% 37.6%
3274535 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.70 53.0 4.40e-01 81.2% 58.2%
4113222 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.70 54.0 4.14e-01 93.8% 37.9%
3583745 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.70 57.0 4.33e-01 89.1% 86.9%
5018714 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.70 51.0 5.26e-01 82.8% 83.3%
None 0.68 50.0 4.02e-01 100.0% 41.7%
4937367 504.1.1.0 a+b two layers › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB 0.68 48.0 3.87e-01 75.0% 45.6%
3927710 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.67 49.0 3.66e-01 78.1% 50.9%
3935534 375.1.9.2 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase › SANTA 0.67 47.0 3.73e-01 75.0% 76.3%
3728831 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.67 46.0 3.48e-01 71.9% 40.0%
3569021 883.1.1.1 a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › LBP_BPI_CETP 0.66 51.0 3.65e-01 82.8% 50.8%
3817752 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.66 45.0 4.42e-01 82.8% 65.7%
3819014 243.3.1.47 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF7074 0.65 46.0 4.27e-01 78.1% 57.1%
3583426 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.65 50.0 3.91e-01 84.4% 60.7%
3742191 11.1.5.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.65 55.0 4.82e-01 93.8% 96.8%
3478366 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.65 48.0 4.09e-01 79.7% 63.8%
4169235 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.64 44.0 3.61e-01 71.9% 38.2%
4942348 504.1.1.0 a+b two layers › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB 0.64 48.0 3.93e-01 81.2% 43.2%
3509864 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.64 48.0 3.87e-01 81.2% 61.6%
5023738 11.1.1.1443 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29994 0.63 50.0 4.19e-01 100.0% 50.0%
3471707 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 56.0 4.33e-01 100.0% 67.1%
3197288 74.1.1.0 beta duplicates or obligate multimers › Transcription factor IIA (TFIIA), beta-barrel domain › Transcription factor IIA (TFIIA), beta-barrel domain › Transcription factor IIA (TFIIA), beta-barrel domain 0.63 46.0 5.07e-01 84.4% 100.0%
3828738 243.1.1.2 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 0.63 47.0 3.63e-01 98.4% 34.2%
3522960 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.63 49.0 3.77e-01 84.4% 52.4%
3604270 283.2.1.0 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like 0.62 47.0 3.74e-01 81.2% 46.9%
3962318 4321.1.1.0 a+b two layers › Peptidoglycan deacetylase N-terminal noncatalytic region › Peptidoglycan deacetylase N-terminal noncatalytic region › Peptidoglycan deacetylase N-terminal noncatalytic region 0.62 49.0 3.51e-01 93.8% 27.8%
3741202 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 46.0 3.56e-01 82.8% 69.0%
3789933 11.10.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like 0.61 46.0 3.96e-01 84.4% 49.5%
3620578 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.61 49.0 3.63e-01 89.1% 78.2%
4028943 212.1.1.0 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.60 51.0 3.50e-01 93.8% 48.2%
3534592 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.60 41.0 4.33e-01 71.9% 87.3%
3430924 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.59 42.0 3.20e-01 100.0% 30.0%
5028178 283.2.1.0 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like 0.59 50.0 3.53e-01 96.9% 52.7%
3674547 243.1.1.25 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_3 0.58 42.0 3.21e-01 76.6% 64.0%
3966482 243.1.1.18 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.58 40.0 3.18e-01 71.9% 34.3%
5040130 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.58 43.0 3.92e-01 81.2% 58.9%
3628355 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.58 42.0 2.75e-01 79.7% 20.0%
1064199 243.1.1.18 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.57 39.0 3.23e-01 73.4% 40.5%
3574276 11.1.4.112 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › DUF3694 0.56 50.0 3.87e-01 100.0% 80.7%
5054514 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 42.0 3.31e-01 79.7% 86.2%
3700323 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.56 40.0 4.24e-01 87.5% 94.5%
3283095 4321.1.1.0 a+b two layers › Peptidoglycan deacetylase N-terminal noncatalytic region › Peptidoglycan deacetylase N-terminal noncatalytic region › Peptidoglycan deacetylase N-terminal noncatalytic region 0.55 44.0 3.23e-01 93.8% 69.1%
2671162 11.1.1.640 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N 0.55 47.0 3.97e-01 100.0% 72.6%
4990857 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.54 43.0 2.85e-01 87.5% 90.8%
3990202 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 47.0 3.99e-01 100.0% 80.9%
3871082 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.53 41.0 3.26e-01 89.1% 86.0%
4884000 243.1.1.1 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › Ring_hydroxyl_B 0.53 40.0 3.15e-01 100.0% 35.3%
3399170 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 44.0 3.79e-01 93.8% 85.7%
5043410 11.1.5.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.53 47.0 3.74e-01 100.0% 73.8%
3826602 243.1.1.25 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_3 0.53 37.0 3.03e-01 100.0% 35.7%
4943914 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.51 40.0 2.61e-01 85.9% 97.1%
5017212 11.1.1.1443 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29994 0.51 39.0 3.41e-01 98.4% 50.4%
3692065 301.7.1.0 a+b three layers › Bacillus chorismate mutase-like › YjgF-like › YjgF-like 0.51 44.0 2.90e-01 100.0% 89.2%
D6 medium residues 510-516_518-523_525-530_766-818_872-960
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04565.22 best RNA_pol_Rpb2_3 23.5 7.00e-05 42.9% 72.1%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4630069 4010.1.1.3 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_3 0.58 40.0 3.42e-01 80.7% 46.5%
4672222 4010.1.1.3 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_3 0.56 45.0 3.61e-01 82.0% 57.8%
4071970 4010.1.1.3 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_3 0.54 40.0 3.39e-01 81.4% 49.4%
4241291 4010.1.1.3 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_3 0.54 43.0 3.62e-01 82.0% 55.3%
4102860 4010.1.1.2 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.54 43.0 3.37e-01 82.0% 43.9%
4660220 4010.1.1.2 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.54 43.0 3.41e-01 82.6% 52.9%
4370831 4010.1.1.3 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_3 0.53 43.0 3.50e-01 82.0% 50.9%
4617138 4010.1.1.3 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_3 0.53 41.0 3.45e-01 80.1% 51.6%
4600941 4010.1.1.0 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.53 41.0 3.59e-01 80.1% 57.8%
5026625 4010.1.1.0 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.52 42.0 3.23e-01 82.0% 45.8%
4932689 4010.1.1.1 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.52 42.0 3.38e-01 82.6% 51.3%
3824946 4010.1.1.2 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.51 41.0 3.16e-01 82.0% 47.5%
3204293 4010.1.1.2 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.51 41.0 3.11e-01 82.6% 41.5%
3639746 4010.1.1.2 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.51 41.0 3.05e-01 82.6% 44.7%
4045157 4010.1.1.2 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.51 40.0 3.33e-01 81.4% 93.5%
5009207 4010.1.1.1 a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.51 41.0 3.07e-01 82.6% 41.2%
D7 medium residues 641-765
PDB
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1zxhA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.50 21.0 2.89e-01 91.2% 78.6%