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IMGVR_UViG_3300003830_000823-3300003830-Ga0051980_100190592

Arc-Vir

Identity

Accession:: IMGVR_UViG_3300003830_000823-3300003830-Ga0051980_100190592 ↗
Kingdom:: archaea

Quality

93.5 mean pLDDT

Cluster

View cluster (2 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 13-124

PDB

Domain cluster: representative

CATH (68)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2qwwC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.77	46.0	4.28e-01	100.0%	48.6%
2fxaA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	45.0	4.00e-01	100.0%	43.6%
4o5vA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	44.0	5.44e-01	97.3%	94.4%
1bjaA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	44.0	4.79e-01	100.0%	71.6%
1on2A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	46.0	5.57e-01	100.0%	100.0%
1t98A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	51.0	5.70e-01	100.0%	94.3%
2rdpA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	45.0	4.14e-01	100.0%	50.0%
1c0wA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	44.0	5.29e-01	99.1%	94.5%
3cdhA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	43.0	4.09e-01	100.0%	50.7%
2a61B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	44.0	4.13e-01	100.0%	51.1%
1tbxB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	46.0	5.04e-01	99.1%	81.1%
1zarA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	46.0	5.11e-01	100.0%	83.1%
4mtdD01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	42.0	4.63e-01	92.9%	75.0%
1stzA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	46.0	5.17e-01	100.0%	88.2%
2g9wA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	40.0	4.93e-01	92.0%	94.0%
5y6iA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	43.0	5.13e-01	100.0%	95.9%
2zo4A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	32.0	4.53e-01	80.4%	100.0%
1jhfA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	41.0	5.08e-01	92.9%	97.1%
6g1dA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	40.0	4.55e-01	99.1%	79.3%
3eyyA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	41.0	4.73e-01	92.9%	84.1%
3szpA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	41.0	4.48e-01	100.0%	75.3%
2zj2A03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	45.0	5.09e-01	98.2%	92.9%
4gcvC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	40.0	3.75e-01	99.1%	48.2%
3o2pE00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	40.0	4.44e-01	93.8%	77.9%
4mqvA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	38.0	4.77e-01	92.9%	98.5%
4rayA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	40.0	4.53e-01	92.9%	81.2%
5tjjA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	39.0	4.66e-01	99.1%	93.2%
1mkmB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	39.0	4.61e-01	98.2%	89.5%
3mwmA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	40.0	4.71e-01	93.8%	93.3%
3dv8A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	42.0	4.83e-01	99.1%	96.2%
2xkoA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	43.0	4.71e-01	99.1%	84.0%
4ev0A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	42.0	4.94e-01	100.0%	98.7%
3b02A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	42.0	4.73e-01	99.1%	89.4%
1i7dA02	1.10.460.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2	0.63	50.0	4.25e-01	100.0%	52.8%
3go5A04	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	36.0	4.57e-01	92.0%	100.0%
2ek5B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	38.0	3.94e-01	97.3%	63.3%
2xigA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	41.0	4.46e-01	92.9%	81.3%
3edpA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	36.0	4.26e-01	94.6%	84.2%
4wcgA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	35.0	4.43e-01	91.1%	100.0%
3f8mA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	33.0	4.17e-01	89.3%	89.2%
5nl9A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	37.0	4.21e-01	89.3%	79.8%
4i2oA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	42.0	4.80e-01	99.1%	97.5%
2bgcA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	43.0	4.49e-01	100.0%	79.2%
2gauA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	42.0	4.85e-01	99.1%	97.5%
6qv3A05	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	47.0	5.09e-01	96.4%	97.8%
2o0yB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	35.0	4.38e-01	92.9%	98.5%
1xmkA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.60	39.0	4.55e-01	100.0%	94.9%
1cf7B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.60	41.0	4.60e-01	96.4%	95.1%
1mswD01	1.10.1320.10	Mainly Alpha › Orthogonal Bundle › T7 RNA polymerase; domain 1 › DNA-directed RNA polymerase, N-terminal domain	0.60	53.0	3.91e-01	100.0%	55.8%
3d0sA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	39.0	4.55e-01	97.3%	95.0%
1w5sA03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	44.0	4.59e-01	100.0%	86.4%
4tv7D01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	36.0	4.02e-01	95.5%	78.8%
4bgdA03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	42.0	4.66e-01	90.2%	94.4%
4p9fA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	33.0	4.09e-01	91.1%	92.5%
3by6C01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	34.0	3.93e-01	91.1%	81.8%
5cvrA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	40.0	4.54e-01	99.1%	95.2%
3e97A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	38.0	4.44e-01	98.2%	97.4%
2ja2A05	1.10.10.350	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.57	42.0	4.44e-01	100.0%	86.7%
3tqnA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	33.0	3.93e-01	91.1%	86.3%
5y2vC01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	35.0	3.92e-01	98.2%	81.2%
1hw1A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.56	35.0	4.07e-01	95.5%	93.3%
2fmyA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.56	39.0	4.45e-01	100.0%	100.0%
5w3gA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.54	42.0	4.29e-01	98.2%	85.5%
2v7fA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.54	46.0	4.29e-01	100.0%	73.4%
6k4yI00	1.10.1810.10	Mainly Alpha › Orthogonal Bundle › Anti-sigma factor AsiA › Anti-Sigma Factor A	0.53	34.0	3.76e-01	97.3%	81.8%
3bjoA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.52	35.0	3.66e-01	100.0%	74.8%
3qx3A04	1.10.268.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3	0.52	35.0	3.65e-01	99.1%	77.0%
6qdjA01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.51	33.0	3.84e-01	87.5%	96.1%

ECOD (75)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4928999	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.74	46.0	5.09e-01	100.0%	77.8%
4571259	101.1.2.46 ↗	alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg	0.73	48.0	5.29e-01	100.0%	83.3%
4287688	101.1.2.46 ↗	alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg	0.72	48.0	5.20e-01	100.0%	80.0%
4596757	101.1.2.89 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_DeoR	0.72	48.0	5.03e-01	100.0%	75.0%
4364450	101.1.2.46 ↗	alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg	0.72	48.0	4.41e-01	100.0%	53.6%
4258325	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	47.0	4.82e-01	100.0%	68.2%
4098825	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	48.0	5.27e-01	100.0%	84.4%
4411875	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	47.0	4.44e-01	100.0%	55.6%
4468068	101.1.2.46 ↗	alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg	0.72	47.0	4.98e-01	100.0%	75.0%
4501841	101.1.2.280 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_12	0.72	47.0	5.40e-01	100.0%	92.5%
4254926	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.71	46.0	5.46e-01	99.1%	97.3%
5008813	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.71	47.0	4.10e-01	100.0%	45.5%
4107841	101.1.2.46 ↗	alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg	0.71	47.0	5.16e-01	100.0%	83.3%
2323740	101.1.2.192 ↗	alpha arrays › HTH › HTH › winged helix domain › B_lactamase-like_C	0.71	38.0	4.99e-01	90.2%	100.0%
4975439	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.71	43.0	4.92e-01	100.0%	81.2%
4129764	101.1.2.280 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_12	0.71	46.0	5.38e-01	100.0%	93.8%
5040941	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	55.0	5.84e-01	99.1%	93.0%
4372770	101.1.2.46 ↗	alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg	0.70	46.0	5.00e-01	100.0%	78.9%
5001364	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	48.0	5.25e-01	100.0%	86.7%
379864	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.70	41.0	3.96e-01	100.0%	50.8%
4928371	101.1.2.927 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF7347	0.70	46.0	5.11e-01	100.0%	83.3%
4679870	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	45.0	4.89e-01	100.0%	77.9%
4042887	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.69	42.0	5.10e-01	98.2%	95.7%
3983569	101.1.2.25 ↗	alpha arrays › HTH › HTH › winged helix domain › FUR	0.69	43.0	3.78e-01	95.5%	43.1%
3450793	101.1.2.386 ↗	alpha arrays › HTH › HTH › winged helix domain › WH_DRP	0.69	50.0	4.61e-01	100.0%	60.0%
3943470	101.1.2.110 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_IclR	0.68	43.0	4.80e-01	100.0%	82.4%
4420420	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	45.0	4.90e-01	100.0%	82.2%
5037574	101.1.2.927 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF7347	0.68	46.0	4.92e-01	100.0%	80.0%
5042212	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	45.0	4.21e-01	99.1%	54.3%
5028701	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	41.0	4.94e-01	100.0%	95.7%
3986601	101.1.2.142 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_Crp_2	0.67	43.0	4.90e-01	99.1%	88.7%
3315363	101.1.2.386 ↗	alpha arrays › HTH › HTH › winged helix domain › WH_DRP	0.67	50.0	4.45e-01	100.0%	55.0%
326087	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.67	43.0	3.94e-01	100.0%	50.3%
4986171	101.1.2.150 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_45	0.67	50.0	5.51e-01	99.1%	98.9%
1806518	101.1.2.1 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_1	0.67	40.0	4.47e-01	100.0%	76.1%
3935894	101.1.2.200 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_65	0.66	42.0	4.54e-01	99.1%	75.8%
4965164	101.1.2.392 ↗	alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH	0.66	47.0	5.04e-01	98.2%	87.4%
3447913	101.1.2.386 ↗	alpha arrays › HTH › HTH › winged helix domain › WH_DRP	0.66	46.0	4.72e-01	100.0%	74.5%
3456829	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.65	48.0	4.92e-01	100.0%	81.0%
3626211	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.65	47.0	5.09e-01	99.1%	89.5%
5055754	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.65	41.0	4.21e-01	95.5%	66.7%
5050212	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.65	43.0	4.61e-01	100.0%	78.9%
3832037	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.65	46.0	3.48e-01	100.0%	30.0%
4326472	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.64	35.0	4.53e-01	90.2%	98.3%
1175670	101.1.2.142 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_Crp_2	0.64	42.0	4.78e-01	99.1%	92.5%
None	—		0.64	51.0	5.31e-01	100.0%	90.5%
4024491	101.1.2.392 ↗	alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH	0.64	51.0	5.14e-01	100.0%	85.5%
None	—		0.64	51.0	5.26e-01	99.1%	90.5%
3268630	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.63	44.0	4.79e-01	100.0%	85.3%
3652381	101.1.2.392 ↗	alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH	0.63	50.0	5.04e-01	100.0%	82.6%
3478717	101.1.2.392 ↗	alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH	0.63	50.0	5.03e-01	100.0%	82.6%
4984732	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.63	44.0	4.86e-01	100.0%	92.0%
None	—		0.63	51.0	5.05e-01	99.1%	80.8%
3733518	101.1.2.392 ↗	alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH	0.63	51.0	4.81e-01	100.0%	71.9%
None	—		0.63	51.0	5.20e-01	99.1%	88.2%
3178978	101.1.2.178 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_61	0.63	50.0	4.76e-01	100.0%	73.1%
3173825	101.1.2.183 ↗	alpha arrays › HTH › HTH › winged helix domain › MUS81-like_WH	0.63	46.0	4.99e-01	100.0%	91.6%
4217857	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.62	36.0	4.53e-01	92.0%	98.5%
1390682	101.1.2.392 ↗	alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH	0.62	49.0	5.12e-01	99.1%	91.3%
4864568	101.1.2.392 ↗	alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH	0.61	50.0	5.17e-01	100.0%	92.5%
4017591	101.1.2.520 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF7779	0.61	41.0	4.64e-01	100.0%	95.0%
224405	101.1.2.142 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_Crp_2	0.61	41.0	4.62e-01	99.1%	92.7%
4553385	101.1.2.5 ↗	alpha arrays › HTH › HTH › winged helix domain › Crp	0.60	42.0	4.70e-01	99.1%	96.4%
3237702	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.60	37.0	4.14e-01	100.0%	81.2%
3718236	4156.1.1.0 ↗	alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like	0.60	49.0	3.78e-01	100.0%	39.2%
1511065	101.1.2.6 ↗	alpha arrays › HTH › HTH › winged helix domain › GntR	0.59	38.0	3.92e-01	98.2%	66.7%
3208874	101.1.2.392 ↗	alpha arrays › HTH › HTH › winged helix domain › SNRNP200_wHTH	0.59	50.0	4.91e-01	100.0%	85.0%
4012689	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.59	49.0	4.83e-01	100.0%	84.2%
4927131	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.58	38.0	4.12e-01	98.2%	81.1%
3269517	101.1.2.183 ↗	alpha arrays › HTH › HTH › winged helix domain › MUS81-like_WH	0.58	44.0	4.56e-01	100.0%	86.7%
4999932	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.58	35.0	3.89e-01	92.9%	75.6%
5049700	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.57	39.0	4.32e-01	100.0%	87.8%
3730487	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.57	48.0	4.41e-01	100.0%	70.3%
3738687	101.1.2.68 ↗	alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34	0.54	42.0	3.92e-01	96.4%	66.4%
3631239	101.1.2.68 ↗	alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34	0.52	47.0	4.01e-01	100.0%	61.6%

D2 high residues 137-284

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF09491.17 best	RE_AlwI	75.8	5.00e-21	100.0%	32.4%

CATH (57)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3cuoD00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.79	40.0	5.01e-01	100.0%	77.7%
2f2eA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.79	41.0	5.17e-01	100.0%	82.4%
2hoeA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.78	32.0	5.16e-01	77.7%	100.0%
2ethA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.78	43.0	4.44e-01	100.0%	56.7%
4hqeA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.77	42.0	4.99e-01	100.0%	76.2%
2nyxB01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.75	42.0	4.29e-01	100.0%	56.3%
1sd4A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	34.0	5.00e-01	89.9%	100.0%
2jt1A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.74	37.0	5.17e-01	92.6%	100.0%
5xnsC00	1.10.10.580	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E	0.74	37.0	5.15e-01	90.5%	100.0%
3l09A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	42.0	5.35e-01	97.3%	97.6%
5jbrA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	37.0	4.74e-01	98.0%	83.7%
2pg4A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.73	42.0	5.17e-01	100.0%	91.2%
1ub9A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	41.0	4.86e-01	100.0%	81.0%
2obpA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.72	40.0	5.23e-01	98.6%	100.0%
4nb5B01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	37.0	4.84e-01	91.9%	88.2%
1tbxB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	39.0	4.83e-01	92.6%	87.8%
2co5A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	40.0	4.95e-01	99.3%	90.2%
1ku9B01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	36.0	4.63e-01	93.9%	85.1%
2xigA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.70	38.0	4.71e-01	93.9%	85.7%
6qpqB00	1.10.10.580	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E	0.70	39.0	5.04e-01	97.3%	98.8%
1yyvB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	38.0	4.31e-01	100.0%	69.6%
3m8eA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	40.0	4.73e-01	100.0%	83.2%
3l7wA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	40.0	4.68e-01	89.2%	81.0%
7jgsG02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.68	42.0	4.98e-01	85.8%	90.8%
4xrfA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	43.0	4.38e-01	96.6%	66.2%
2fbiA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	43.0	4.50e-01	90.5%	70.6%
2gxgA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	42.0	4.36e-01	90.5%	67.1%
2rdpA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	42.0	4.32e-01	90.5%	66.4%
1p4xA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	41.0	4.36e-01	97.3%	70.1%
2fbhA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	43.0	4.50e-01	90.5%	70.8%
4ejoA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.66	40.0	4.57e-01	93.9%	80.4%
7dvrA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	43.0	4.43e-01	95.9%	69.5%
4hw0C00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	35.0	4.21e-01	86.5%	79.6%
5dcaA11	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	45.0	5.22e-01	89.9%	99.0%
4g9yA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	41.0	4.26e-01	93.2%	67.6%
7xc2A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.65	40.0	4.69e-01	100.0%	86.8%
6pcoC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	41.0	4.40e-01	91.2%	72.7%
3e6mA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	40.0	4.08e-01	90.5%	63.7%
5e1wA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	42.0	4.07e-01	91.9%	59.5%
8agaA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	40.0	4.30e-01	91.9%	73.8%
3bpvA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	41.0	4.33e-01	90.5%	72.3%
2b0lC00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.60	34.0	4.09e-01	100.0%	86.2%
7uvpA02	3.30.70.870	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3	0.60	24.0	3.38e-01	75.7%	76.8%
3jcmH04	3.30.70.870	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3	0.59	24.0	3.22e-01	75.7%	68.8%
1s12A00	3.30.70.1490	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp	0.59	27.0	3.24e-01	79.1%	62.8%
1t6sA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	31.0	3.85e-01	91.2%	83.7%
3zcoA00	1.10.10.2450	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.59	43.0	4.65e-01	100.0%	89.0%
1xb4B02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	31.0	4.16e-01	88.5%	100.0%
3jamK00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	33.0	3.99e-01	99.3%	84.4%
3keyA02	3.30.1370.230	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Stn1, C-terminal wHTH domain	0.58	34.0	4.28e-01	87.2%	97.7%
1ci4A00	1.10.150.40	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Barrier-to-autointegration factor, BAF	0.56	30.0	3.70e-01	93.2%	85.2%
2v1nA01	1.10.10.2030	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DNA/RNA-binding protein Kin17, conserved domain	0.55	35.0	4.08e-01	98.6%	91.1%
6u9hF02	3.30.70.1150	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2	0.55	22.0	2.87e-01	75.7%	63.6%
4izzB03	1.10.10.1670	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › HetR, flap domain	0.54	40.0	4.55e-01	96.6%	100.0%
4lvnP00	3.30.70.2380	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.53	24.0	3.04e-01	78.4%	71.6%
1vq0A02	3.90.1280.10	Alpha Beta › Alpha-Beta Complex › CBS domain Like › HSP33 redox switch-like	0.52	22.0	3.18e-01	91.2%	94.7%
7npaA02	3.30.70.3340	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.50	25.0	3.14e-01	79.7%	78.8%

ECOD (85)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5082589	101.1.2.14 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_5	0.81	41.0	5.51e-01	98.0%	91.3%
5040897	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.79	41.0	5.67e-01	100.0%	100.0%
4996616	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.79	33.0	5.16e-01	73.6%	100.0%
5039584	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.79	38.0	5.06e-01	92.6%	85.0%
4972222	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.78	38.0	4.64e-01	95.3%	70.0%
5028550	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.78	36.0	3.88e-01	91.2%	51.2%
4934328	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.78	38.0	5.38e-01	94.6%	100.0%
4979047	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.77	40.0	3.88e-01	100.0%	44.8%
3280999	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.77	40.0	3.96e-01	95.9%	47.7%
5079044	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.77	40.0	5.47e-01	98.6%	100.0%
3282605	101.1.2.508 ↗	alpha arrays › HTH › HTH › winged helix domain › PF25872	0.77	40.0	5.37e-01	100.0%	95.0%
5004231	101.1.2.896 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF2551	0.76	45.0	5.42e-01	100.0%	89.5%
5005196	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.76	39.0	5.20e-01	98.6%	92.5%
3461891	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.75	36.0	4.37e-01	93.2%	68.0%
5013440	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.75	42.0	4.39e-01	99.3%	58.6%
5030899	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.75	37.0	5.17e-01	93.2%	100.0%
5040871	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.75	39.0	5.12e-01	85.1%	92.5%
5058358	101.1.2.110 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_IclR	0.74	41.0	5.22e-01	100.0%	92.9%
4926786	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.74	39.0	5.09e-01	100.0%	92.5%
4951019	101.1.2.896 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF2551	0.74	43.0	5.26e-01	100.0%	89.5%
5010793	101.1.2.15 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR	0.74	39.0	5.26e-01	100.0%	100.0%
4967461	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.73	39.0	4.81e-01	100.0%	81.1%
4938723	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.73	39.0	4.18e-01	97.3%	59.2%
5014224	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.73	34.0	4.78e-01	81.1%	92.9%
4976066	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.73	40.0	5.32e-01	91.2%	100.0%
4992389	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	38.0	4.62e-01	86.5%	77.9%
4968342	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	39.0	4.55e-01	100.0%	73.3%
5016457	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	39.0	5.08e-01	98.0%	92.9%
3721121	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	39.0	4.67e-01	100.0%	78.0%
4980177	101.1.2.150 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_45	0.71	41.0	4.54e-01	90.5%	69.2%
5039088	101.1.2.110 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_IclR	0.71	42.0	4.25e-01	95.3%	58.6%
5065249	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.71	42.0	5.32e-01	90.5%	100.0%
5058434	101.1.2.14 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_5	0.71	41.0	4.42e-01	94.6%	64.6%
5013384	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.71	39.0	3.95e-01	97.3%	53.3%
5017587	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.71	36.0	4.61e-01	98.0%	83.5%
3441807	101.1.2.386 ↗	alpha arrays › HTH › HTH › winged helix domain › WH_DRP	0.71	42.0	5.28e-01	99.3%	100.0%
3716076	101.1.2.65 ↗	alpha arrays › HTH › HTH › winged helix domain › Rad21_Rec8	0.71	38.0	5.01e-01	100.0%	98.7%
3500170	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.71	39.0	4.87e-01	100.0%	87.8%
4649222	101.1.2.15 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR	0.71	46.0	4.88e-01	91.2%	73.8%
4992272	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.71	42.0	4.68e-01	86.5%	73.3%
4965139	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	37.0	4.80e-01	100.0%	92.5%
4399101	101.1.2.88 ↗	alpha arrays › HTH › HTH › winged helix domain › Dimerisation	0.70	40.0	4.60e-01	100.0%	75.5%
4940054	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	40.0	4.86e-01	100.0%	87.4%
3651024	101.1.2.65 ↗	alpha arrays › HTH › HTH › winged helix domain › Rad21_Rec8	0.70	41.0	4.65e-01	100.0%	77.3%
4025539	101.1.2.22 ↗	alpha arrays › HTH › HTH › winged helix domain › PCI	0.69	36.0	4.81e-01	96.6%	97.3%
5067775	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.69	40.0	5.11e-01	95.3%	98.8%
3426878	101.1.2.386 ↗	alpha arrays › HTH › HTH › winged helix domain › WH_DRP	0.69	43.0	5.03e-01	100.0%	90.0%
3167163	101.1.2.65 ↗	alpha arrays › HTH › HTH › winged helix domain › Rad21_Rec8	0.69	41.0	4.95e-01	100.0%	91.6%
3493997	101.1.2.22 ↗	alpha arrays › HTH › HTH › winged helix domain › PCI	0.69	35.0	4.72e-01	98.6%	96.0%
5035546	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	36.0	4.53e-01	90.5%	85.9%
3296862	101.1.2.22 ↗	alpha arrays › HTH › HTH › winged helix domain › PCI	0.68	35.0	4.69e-01	98.6%	96.0%
4991749	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	39.0	4.12e-01	100.0%	61.5%
5048954	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	40.0	4.48e-01	82.4%	73.9%
3943466	101.1.2.15 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR	0.68	45.0	4.35e-01	90.5%	61.3%
5072417	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.68	38.0	4.16e-01	87.8%	65.8%
3500507	101.1.2.166 ↗	alpha arrays › HTH › HTH › winged helix domain › MCM6_C	0.68	46.0	5.40e-01	98.6%	98.1%
3666427	101.1.2.386 ↗	alpha arrays › HTH › HTH › winged helix domain › WH_DRP	0.67	40.0	3.96e-01	100.0%	54.8%
3829267	101.1.2.88 ↗	alpha arrays › HTH › HTH › winged helix domain › Dimerisation	0.67	39.0	4.27e-01	100.0%	70.0%
3610460	101.1.2.22 ↗	alpha arrays › HTH › HTH › winged helix domain › PCI	0.67	37.0	4.83e-01	95.3%	100.0%
1291586	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.66	43.0	4.51e-01	91.2%	70.5%
5001357	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.66	43.0	5.08e-01	89.9%	97.0%
4003475	101.1.2.166 ↗	alpha arrays › HTH › HTH › winged helix domain › MCM6_C	0.66	43.0	5.12e-01	92.6%	98.0%
3971712	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.66	43.0	4.58e-01	93.2%	74.6%
3680635	101.1.2.154 ↗	alpha arrays › HTH › HTH › winged helix domain › CDT1_C	0.66	39.0	4.59e-01	93.2%	82.9%
4201017	101.1.2.15 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR	0.65	42.0	4.16e-01	90.5%	60.6%
3286243	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.64	42.0	4.26e-01	90.5%	66.0%
3279462	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.64	40.0	4.10e-01	91.2%	64.1%
3285968	101.1.2.15 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR	0.63	42.0	4.28e-01	91.2%	67.6%
1888715	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.63	42.0	4.42e-01	91.9%	73.5%
3954543	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.62	42.0	4.32e-01	93.2%	71.3%
3470890	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.61	40.0	4.72e-01	88.5%	94.3%
3601388	304.24.1.0 ↗	a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like	0.61	23.0	3.25e-01	75.0%	69.3%
3802262	101.1.2.386 ↗	alpha arrays › HTH › HTH › winged helix domain › WH_DRP	0.60	38.0	3.97e-01	100.0%	66.4%
3487542	101.1.2.65 ↗	alpha arrays › HTH › HTH › winged helix domain › Rad21_Rec8	0.59	39.0	4.37e-01	96.6%	86.1%
5045697	101.1.2.1 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_1	0.58	34.0	3.99e-01	100.0%	81.9%
3632795	101.1.2.309 ↗	alpha arrays › HTH › HTH › winged helix domain › GPAT_C	0.58	39.0	4.45e-01	98.6%	92.7%
3592665	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.57	38.0	4.46e-01	100.0%	97.1%
3604748	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.57	43.0	3.73e-01	96.6%	53.5%
3785110	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.56	41.0	4.34e-01	97.3%	83.0%
5035783	304.120.1.6 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer	0.55	26.0	3.36e-01	72.3%	78.8%
4999182	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.54	28.0	3.57e-01	79.7%	92.0%
5049534	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.53	31.0	3.76e-01	81.1%	95.3%
4223303	304.37.1.1 ↗	a+b two layers › Alpha-beta plaits › Sulfite reductase, domains 1 and 3 › Sulfite reductase, domains 1 and 3 › NIR_SIR_ferr	0.52	24.0	3.05e-01	77.0%	72.9%
4584775	101.1.2.198 ↗	alpha arrays › HTH › HTH › winged helix domain › ORC1_wHTH	0.51	42.0	4.28e-01	100.0%	89.0%
3848908	5001.1.1.1 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1	0.51	40.0	3.13e-01	83.1%	77.3%

D3 medium residues 311-407

PDB

Domain cluster: representative

CATH (20)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1gnlA01	1.20.1270.20	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.85	61.0	5.29e-01	74.2%	73.4%
1gvnA00	1.10.8.130	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.84	59.0	6.23e-01	72.2%	95.4%
2oexA02	1.20.140.50	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains	0.80	61.0	4.72e-01	79.4%	87.8%
2pbeA02	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.79	57.0	5.22e-01	75.3%	65.9%
2p1aB01	1.20.120.450	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain	0.74	50.0	4.36e-01	70.1%	98.6%
1xvhB00	1.20.120.1850	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Ebh helix bundles repeating unit (S and A modules)	0.73	53.0	4.99e-01	76.3%	65.3%
2uuiA00	1.20.120.550	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain	0.70	55.0	4.72e-01	84.5%	61.9%
5nl6A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.66	47.0	4.58e-01	74.2%	91.7%
2fnaA02	1.10.8.60	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.66	38.0	4.28e-01	73.2%	73.7%
1r0dA00	1.20.1410.10	Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain	0.65	51.0	4.11e-01	85.6%	66.8%
7s0rB01	1.20.81.20	Mainly Alpha › Up-down Bundle › Receptor-associated Protein ›	0.65	46.0	5.11e-01	74.2%	100.0%
2lquA01	1.20.1420.40	Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein	0.62	47.0	4.08e-01	83.5%	51.3%
7p3rA01	1.20.1170.10	Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; ›	0.60	46.0	3.22e-01	81.4%	48.3%
3uumA00	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.59	46.0	4.29e-01	83.5%	95.1%
2odvA01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	41.0	3.91e-01	75.3%	96.4%
3edvB01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	43.0	3.86e-01	81.4%	83.1%
1jmwA00	1.20.120.30	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain	0.55	41.0	3.71e-01	82.5%	75.3%
2xvlA03	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.53	37.0	2.60e-01	73.2%	90.7%
6g94A00	1.20.950.20	Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C	0.52	36.0	2.96e-01	72.2%	66.9%
3whjA00	6.10.140.1710	Special › Helix non-globular › Helix Hairpins ›	0.51	40.0	3.88e-01	85.6%	92.8%

ECOD (14)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4956012	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.81	59.0	5.79e-01	76.3%	84.8%
3308724	3721.1.1.2 ↗	alpha bundles › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › Protein regulator of cytokinesis 1 (PRC1) dimerization domain › MAP65_ASE1	0.81	60.0	6.28e-01	77.3%	83.3%
3556512	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.80	63.0	5.92e-01	82.5%	95.7%
3455096	3722.1.1.1 ↗	alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › MAP65_ASE1	0.80	57.0	4.21e-01	73.2%	53.3%
3654060	3722.1.1.1 ↗	alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › MAP65_ASE1	0.79	60.0	4.44e-01	78.4%	33.6%
3224820	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.79	57.0	6.01e-01	74.2%	90.6%
3924238	3722.1.1.0 ↗	alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain	0.72	55.0	4.15e-01	81.4%	34.9%
3651890	604.1.1.3 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › MAP65_ASE1	0.71	51.0	4.07e-01	74.2%	38.9%
3470751	3755.3.1.297 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9	0.68	46.0	3.93e-01	70.1%	92.5%
3176849	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.67	54.0	5.12e-01	86.6%	83.5%
5021829	605.6.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like	0.61	36.0	3.75e-01	94.8%	63.3%
3746634	604.1.1.1 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin	0.60	46.0	4.22e-01	81.4%	87.2%
4547657	4106.1.1.1 ↗	few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC	0.59	50.0	3.80e-01	94.8%	70.0%
4958743	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.57	45.0	4.26e-01	83.5%	95.7%

D4 medium residues 408-537

PDB

Domain cluster: rep: hypothetical_protein_D1R72_gp005__YP_009507402__Heterosigma_akashiwo_virus_01__97195__D259-392

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF09491.17 best	RE_AlwI	133.0	2.20e-38	100.0%	30.8%

CATH (53)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2ewfA03	3.40.91.50	Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease ›	0.94	92.0	7.33e-01	100.0%	57.8%
2p14A00	3.40.91.50	Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease ›	0.92	84.0	7.23e-01	100.0%	65.6%
2e52B01	3.40.91.70	Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Type II restriction endonuclease, HindIII	0.78	63.0	5.19e-01	100.0%	49.1%
1y88A01	3.40.1350.10	Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 ›	0.72	62.0	6.36e-01	100.0%	94.4%
3dvoA00	3.40.91.10	Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease ›	0.72	68.0	4.90e-01	100.0%	65.9%
3h7aA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.66	60.0	5.08e-01	99.2%	85.4%
3vc7A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.66	58.0	4.81e-01	97.7%	81.4%
1u8xX01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.65	57.0	5.23e-01	93.8%	93.4%
4dyvA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.65	59.0	5.01e-01	100.0%	85.9%
7kx9A02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.65	48.0	4.66e-01	100.0%	69.4%
2ziuB01	3.40.50.10130	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.64	54.0	5.21e-01	99.2%	79.2%
3e48A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.63	56.0	4.99e-01	97.7%	79.2%
2eo0B00	3.40.1350.10	Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 ›	0.62	49.0	5.07e-01	99.2%	87.1%
3hpaA02	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.62	51.0	3.83e-01	87.7%	50.2%
4rz2B00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.61	55.0	4.44e-01	100.0%	87.9%
6r8gA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.61	53.0	5.20e-01	96.2%	95.1%
3c5hA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.61	55.0	4.54e-01	100.0%	83.2%
3b5iB01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.60	53.0	4.32e-01	96.9%	83.3%
3t15A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.60	46.0	4.39e-01	93.1%	68.4%
3g64A01	3.90.226.10	Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1	0.59	42.0	3.55e-01	72.3%	90.2%
4o1eB00	3.20.20.20	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like	0.59	50.0	3.98e-01	91.5%	57.3%
3e7pA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.59	53.0	4.26e-01	99.2%	92.9%
6kd0A01	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.58	53.0	3.95e-01	100.0%	68.1%
4wcjA00	3.20.20.370	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycoside hydrolase/deacetylase	0.58	51.0	4.21e-01	95.4%	88.4%
4az3A00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.58	47.0	3.74e-01	86.2%	62.9%
2vtfA01	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.58	47.0	3.53e-01	89.2%	61.8%
1im8B00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.57	51.0	4.29e-01	99.2%	98.2%
4wd1A01	3.40.50.12780	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain	0.57	51.0	3.60e-01	99.2%	70.2%
6jtdA01	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.57	51.0	4.07e-01	99.2%	89.5%
4ntcA02	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.57	46.0	4.74e-01	100.0%	89.5%
1flaA00	3.40.50.360	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain	0.57	48.0	4.76e-01	100.0%	87.7%
4d02A02	3.40.50.360	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain	0.57	49.0	4.80e-01	100.0%	87.4%
2ohhA02	3.40.50.360	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain	0.57	50.0	4.87e-01	100.0%	88.9%
4hpnA02	3.20.20.120	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain	0.57	46.0	3.70e-01	88.5%	44.7%
1fcdA02	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.56	50.0	4.92e-01	99.2%	89.9%
3bypA00	3.30.70.1350	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain	0.56	36.0	4.28e-01	84.6%	100.0%
2oogD00	3.20.20.190	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphatidylinositol (PI) phosphodiesterase	0.56	48.0	3.88e-01	96.2%	82.1%
1yt8A02	3.40.250.10	Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain	0.56	39.0	4.17e-01	92.3%	85.2%
3sm3A00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.56	49.0	4.17e-01	96.9%	86.3%
1eucA02	3.40.50.261	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains	0.56	51.0	4.65e-01	100.0%	77.1%
1wp0A00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.55	39.0	3.68e-01	93.1%	60.0%
7pt4A01	3.40.50.970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	0.54	47.0	4.16e-01	96.2%	74.2%
6p0wA01	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.54	41.0	4.05e-01	99.2%	76.3%
2hu8A02	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.53	47.0	3.82e-01	100.0%	75.5%
2pg3A00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.53	48.0	4.04e-01	100.0%	70.0%
3fnrA02	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.53	48.0	3.67e-01	100.0%	91.4%
6oibA01	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.53	48.0	4.59e-01	100.0%	90.1%
2m72A00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.53	38.0	3.64e-01	93.8%	63.4%
3rc3A04	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.53	41.0	4.00e-01	83.1%	79.3%
2xi5A00	3.40.91.60	Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease ›	0.52	44.0	3.95e-01	100.0%	65.2%
2e18A00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.52	41.0	3.29e-01	83.8%	84.4%
6tmvB01	3.50.7.10	Alpha Beta › 3-Layer(bba) Sandwich › GroEL › GroEL	0.51	43.0	4.02e-01	90.0%	90.6%
2x6qA02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.50	46.0	4.00e-01	100.0%	66.0%

ECOD (77)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1721531	2008.1.1.45 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_AlwI	0.94	92.0	7.32e-01	100.0%	57.5%
198173	2008.1.1.45 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_AlwI	0.92	84.0	7.23e-01	100.0%	65.6%
4446863	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.83	58.0	5.94e-01	100.0%	74.8%
5073158	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.80	68.0	6.75e-01	100.0%	85.2%
4940209	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.78	49.0	5.62e-01	94.6%	85.3%
5011600	2008.1.1.108 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234	0.77	60.0	6.48e-01	100.0%	95.5%
5035773	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.76	62.0	6.00e-01	100.0%	76.6%
4946571	2008.1.1.85 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_TdeIII	0.75	71.0	5.97e-01	100.0%	64.9%
4933191	2008.1.1.220 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_10	0.74	60.0	5.73e-01	97.7%	73.3%
3941843	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.74	69.0	5.09e-01	100.0%	50.5%
2715553	2008.1.1.34 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Card1_endonuc	0.73	64.0	6.66e-01	100.0%	99.2%
5009647	2008.1.1.235 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF26618	0.73	61.0	5.12e-01	99.2%	54.3%
4999754	2008.1.1.5 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NucS_C	0.73	59.0	6.22e-01	100.0%	95.7%
5021928	2008.1.1.87 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C	0.71	63.0	5.82e-01	97.7%	75.6%
5035436	2008.1.1.16 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat	0.71	62.0	6.18e-01	100.0%	88.9%
4385485	2008.1.1.82 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RRG7	0.71	67.0	5.83e-01	100.0%	86.2%
4010728	2008.1.1.87 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C	0.71	64.0	6.31e-01	100.0%	91.1%
4062706	2008.1.1.82 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RRG7	0.71	66.0	5.47e-01	100.0%	87.3%
4058772	2008.1.1.82 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RRG7	0.70	65.0	5.34e-01	100.0%	88.4%
4953503	2008.1.1.107 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD	0.69	56.0	4.74e-01	100.0%	54.5%
3102571	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.69	63.0	6.14e-01	100.0%	90.2%
3583806	7590.1.1.6 ↗	a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › ArgoMid	0.68	51.0	4.65e-01	100.0%	59.4%
5018195	2008.1.1.87 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C	0.68	62.0	5.99e-01	100.0%	87.6%
3593046	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.67	54.0	5.13e-01	99.2%	74.0%
5043442	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.66	61.0	4.88e-01	100.0%	80.8%
5005960	2008.1.1.4 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4	0.66	52.0	4.64e-01	90.0%	59.2%
3839790	2008.1.1.95 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DpnII	0.66	57.0	4.44e-01	100.0%	44.8%
3419363	7590.1.1.6 ↗	a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › ArgoMid	0.65	51.0	4.67e-01	100.0%	64.8%
4157798	2008.1.1.95 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DpnII	0.65	56.0	5.32e-01	100.0%	80.7%
3379260	7590.1.1.2 ↗	a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi	0.64	48.0	4.40e-01	100.0%	58.9%
3667573	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.64	45.0	3.76e-01	70.8%	90.7%
5073860	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.63	56.0	5.52e-01	97.7%	94.2%
5041156	2008.1.1.59 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1	0.63	54.0	4.94e-01	90.0%	80.0%
3729330	7590.1.1.2 ↗	a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi	0.63	47.0	4.33e-01	100.0%	61.2%
1144868	2008.1.1.66 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ArenaCapSnatch	0.62	47.0	4.32e-01	97.7%	60.9%
4241367	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.62	56.0	5.33e-01	100.0%	88.4%
3170447	2008.6.1.1 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Acetyl-CoA carboxylase AC4 and AC5 domains › Acetyl-CoA carboxylase AC4 and AC5 domains › ACC_central	0.62	56.0	4.57e-01	100.0%	75.1%
3937765	2008.1.1.7 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ERCC4	0.62	51.0	4.66e-01	100.0%	66.3%
4947545	2008.1.1.4 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4	0.62	51.0	4.49e-01	90.0%	60.0%
3695358	7590.1.1.3 ↗	a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi,ArgoMid	0.62	47.0	4.37e-01	100.0%	63.0%
5080245	2008.1.1.4 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4	0.62	52.0	4.56e-01	90.0%	62.6%
4930402	2008.1.1.59 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1	0.61	52.0	4.67e-01	89.2%	73.7%
4988165	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.61	56.0	5.07e-01	100.0%	97.1%
3680941	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.61	48.0	5.16e-01	81.5%	100.0%
5042023	2008.1.1.4 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4	0.61	50.0	4.39e-01	90.0%	59.5%
3273092	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.61	44.0	3.32e-01	90.0%	30.6%
2794325	2004.1.1.175 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ParA	0.61	55.0	4.34e-01	100.0%	82.1%
4972927	2003.1.5.30 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_7	0.61	55.0	4.03e-01	99.2%	97.1%
4929251	2008.1.1.4 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4	0.61	49.0	4.31e-01	90.0%	58.4%
4507112	2004.1.1.175 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ParA	0.61	55.0	4.33e-01	100.0%	82.9%
None	—		0.61	54.0	4.47e-01	100.0%	92.2%
3940369	2007.9.1.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain	0.61	52.0	5.09e-01	100.0%	84.1%
3578229	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.61	42.0	3.19e-01	90.0%	30.0%
3366495	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.60	43.0	3.16e-01	90.0%	28.8%
3988470	2008.1.1.51 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › McrBC	0.60	56.0	5.24e-01	100.0%	89.7%
2116981	2008.1.1.66 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ArenaCapSnatch	0.59	45.0	3.93e-01	96.9%	53.1%
5083237	2007.2.1.3 ↗	a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › FMN_red	0.59	53.0	4.67e-01	100.0%	90.0%
4458074	7516.1.1.102 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2, Glyco_trans_2_3	0.58	44.0	2.82e-01	78.5%	20.5%
4027084	2006.1.6.12 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2	0.58	51.0	4.62e-01	100.0%	93.5%
3248910	2003.1.5.89 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Anamorsin_N	0.57	51.0	3.86e-01	99.2%	55.9%
3744163	2003.1.5.95 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › TRM13	0.56	51.0	3.83e-01	99.2%	68.6%
3691413	7590.1.1.0 ↗	a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs	0.55	44.0	3.88e-01	100.0%	56.9%
3359389	2006.1.1.6 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Acid_phosphat_B	0.55	42.0	3.55e-01	80.8%	74.2%
4982374	2485.1.1.0 ↗	a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like	0.55	39.0	3.68e-01	93.1%	60.0%
4963305	2005.1.1.3 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp	0.54	39.0	3.94e-01	74.6%	83.5%
4991756	2003.1.2.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain	0.53	47.0	4.52e-01	100.0%	84.7%
4965730	2005.1.1.0 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains	0.53	38.0	3.88e-01	74.6%	85.4%
3191716	2496.1.1.1 ↗	a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › CRAL_TRIO	0.52	45.0	3.66e-01	99.2%	61.1%
2629991	2496.1.1.3 ↗	a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › SiaC	0.52	40.0	4.10e-01	83.1%	96.1%
5071639	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.52	42.0	3.30e-01	90.0%	59.3%
3736223	2496.1.1.1 ↗	a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › CRAL_TRIO	0.51	45.0	3.97e-01	99.2%	74.4%
3170415	7522.1.1.0 ↗	a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like	0.51	41.0	4.17e-01	94.6%	86.9%
3703764	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.51	44.0	3.89e-01	93.8%	83.7%
3636009	2004.1.1.366 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N	0.51	40.0	3.64e-01	85.4%	61.1%
3593609	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.51	44.0	3.43e-01	93.8%	57.1%
3305506	2484.1.1.1 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70	0.50	43.0	4.32e-01	98.5%	91.1%
4073364	2005.1.1.38 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTU2	0.50	44.0	3.39e-01	97.7%	59.7%

D5 medium residues 538-595

PDB

Domain cluster: representative

CATH (28)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1k32A03	3.30.750.44	Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA ›	0.71	56.0	5.24e-01	100.0%	70.8%
1r1dA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.69	47.0	3.15e-01	75.9%	17.4%
2klqA00	1.20.58.870	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.68	47.0	3.81e-01	72.4%	38.6%
1t07A00	1.10.3880.10	Mainly Alpha › Orthogonal Bundle › YggX-like › Fe(II) trafficking protein YggX	0.68	55.0	4.94e-01	96.6%	64.2%
1tfeA02	1.10.286.20	Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 ›	0.68	47.0	5.06e-01	86.2%	95.6%
2gsvA00	6.10.140.40	Special › Helix non-globular › Helix Hairpins ›	0.66	46.0	4.42e-01	74.1%	65.7%
4qmaA01	1.20.5.440	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain	0.66	43.0	4.81e-01	72.4%	97.5%
7dluA01	1.10.287.1260	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.66	47.0	4.01e-01	79.3%	51.4%
1cbyA00	3.40.198.10	Alpha Beta › 3-Layer(aba) Sandwich › Delta-endotoxin CytB › Delta-endotoxin CytB-like	0.65	44.0	2.97e-01	70.7%	44.1%
4j0eA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.63	49.0	3.40e-01	86.2%	26.7%
7s0rB01	1.20.81.20	Mainly Alpha › Up-down Bundle › Receptor-associated Protein ›	0.63	53.0	4.89e-01	100.0%	75.0%
4k7cA01	3.90.70.10	Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases	0.63	52.0	3.21e-01	98.3%	48.2%
3ed5A02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.61	50.0	4.56e-01	100.0%	66.7%
3k1zA02	1.10.150.720	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Haloacid dehalogenase-like hydrolase	0.61	51.0	4.66e-01	100.0%	79.8%
3bqyA02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.60	50.0	3.84e-01	100.0%	88.0%
2go7A02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.60	36.0	3.48e-01	70.7%	50.7%
1sgwA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.59	48.0	3.37e-01	100.0%	27.0%
4f5cA04	1.25.50.20	Mainly Alpha › Alpha Horseshoe › Zincin-like fold ›	0.58	38.0	2.38e-01	84.5%	11.7%
3b9qA01	1.20.120.140	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain	0.58	50.0	4.34e-01	96.6%	85.4%
1cxzB00	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.56	42.0	3.80e-01	84.5%	87.2%
1e1dA02	1.20.1270.20	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.56	49.0	4.36e-01	100.0%	69.0%
2l35A00	1.10.287.770	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like	0.56	38.0	3.77e-01	72.4%	79.4%
1mw9X02	1.10.460.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2	0.56	46.0	3.49e-01	100.0%	90.8%
1pixA03	3.90.226.10	Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1	0.54	42.0	2.74e-01	91.4%	70.6%
3qf7A02	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.53	38.0	3.79e-01	79.3%	100.0%
1j1jA02	1.20.58.200	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2	0.53	41.0	3.75e-01	91.4%	67.1%
3axjB02	1.20.58.200	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2	0.52	40.0	3.63e-01	89.7%	64.7%
2yevA02	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.51	37.0	3.44e-01	77.6%	73.0%

ECOD (48)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4567807	397.7.1.6 ↗	few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 › PF29718	0.80	55.0	5.31e-01	72.4%	64.6%
3260418	5043.1.1.0 ↗	extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like	0.77	53.0	5.15e-01	72.4%	75.4%
5028558	5058.1.1.2 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st	0.77	56.0	4.73e-01	79.3%	54.0%
3621479	6026.1.1.1 ↗	alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21	0.75	53.0	4.72e-01	75.9%	57.6%
5075474	164.1.1.1 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2	0.74	52.0	4.64e-01	75.9%	53.8%
4296658	164.1.1.1 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2	0.73	52.0	4.32e-01	75.9%	43.9%
3211845	103.1.1.0 ↗	alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain	0.73	48.0	5.50e-01	74.1%	100.0%
4317794	5058.1.1.1 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st	0.73	53.0	4.43e-01	79.3%	51.4%
5034026	5058.1.1.16 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1	0.73	53.0	4.39e-01	79.3%	50.5%
4101335	2006.1.4.8 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_5	0.72	53.0	3.55e-01	79.3%	21.8%
3423700	6026.1.1.0 ↗	alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain	0.71	50.0	5.42e-01	75.9%	95.6%
5054950	186.1.1.0 ↗	alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N	0.71	53.0	4.16e-01	100.0%	37.6%
4597483	5058.1.1.1 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st	0.70	51.0	4.11e-01	79.3%	45.0%
5011971	164.1.1.1 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2	0.70	49.0	4.44e-01	77.6%	53.8%
2983211	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.70	51.0	4.08e-01	77.6%	43.0%
5012687	5058.1.1.16 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1	0.70	52.0	4.51e-01	82.8%	67.4%
3513381	4082.1.1.0 ↗	alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain	0.70	50.0	4.99e-01	77.6%	76.7%
3966348	5058.1.1.16 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1	0.69	51.0	4.50e-01	79.3%	55.3%
3463858	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.69	47.0	3.99e-01	72.4%	45.0%
3331809	375.1.9.23 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase › Sterile	0.69	49.0	3.55e-01	77.6%	26.9%
4669981	230.3.1.0 ↗	a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain	0.69	51.0	3.89e-01	94.8%	33.1%
366729	164.1.1.1 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2	0.69	49.0	4.17e-01	77.6%	45.5%
3491670	614.1.1.0 ↗	alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain	0.68	49.0	4.99e-01	77.6%	83.6%
4120017	230.3.1.1 ↗	a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS	0.68	52.0	3.93e-01	94.8%	34.3%
3258047	5041.1.1.0 ↗	extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C	0.68	52.0	3.89e-01	84.5%	37.3%
5063587	611.9.1.0 ↗	alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain	0.68	56.0	5.01e-01	94.8%	83.5%
3764064	4009.1.1.0 ↗	alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins	0.68	56.0	5.06e-01	98.3%	80.0%
3590184	3711.1.1.0 ↗	alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein	0.67	48.0	3.78e-01	79.3%	39.3%
5023792	148.1.3.19 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3	0.67	57.0	4.65e-01	96.6%	72.7%
3882597	4009.1.1.0 ↗	alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins	0.67	56.0	4.98e-01	100.0%	73.3%
3643105	6026.1.1.1 ↗	alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21	0.66	51.0	3.75e-01	84.5%	32.3%
4318142	230.3.1.1 ↗	a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS	0.66	53.0	4.06e-01	89.7%	37.1%
3781350	5041.1.1.20 ↗	extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › PF26669	0.65	50.0	4.04e-01	86.2%	44.2%
3645559	650.1.1.1 ↗	alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ	0.63	43.0	3.85e-01	74.1%	50.0%
3248808	268.1.1.0 ↗	a+b two layers › Sterol carrier protein-like › Sterol carrier protein, SCP-related › Sterol carrier protein, SCP-related	0.62	54.0	4.55e-01	100.0%	86.0%
2647290	225.1.1.6 ↗	a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_2	0.62	43.0	4.00e-01	75.9%	55.0%
4970333	5058.1.1.0 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region	0.61	44.0	3.85e-01	79.3%	52.6%
4981035	5058.1.1.16 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1	0.61	46.0	4.48e-01	84.5%	83.1%
4938578	2003.1.1.28 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N	0.61	49.0	3.52e-01	91.4%	32.4%
3607406	6026.1.1.0 ↗	alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain	0.60	46.0	4.32e-01	93.1%	77.5%
5047182	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.59	44.0	4.31e-01	84.5%	78.5%
4947163	601.30.1.4 ↗	alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › MMR_HSR1	0.59	48.0	3.68e-01	100.0%	56.2%
2388822	191.1.1.1 ↗	alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_1	0.59	49.0	4.02e-01	100.0%	91.6%
3784055	192.24.1.0 ↗	alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain	0.57	40.0	3.30e-01	79.3%	38.5%
3067085	5081.1.1.0 ↗	alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like	0.57	47.0	3.46e-01	100.0%	39.3%
3591480	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.55	46.0	3.09e-01	100.0%	46.9%
4211233	4120.1.1.60 ↗	few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › GlutR_dimer	0.54	40.0	3.78e-01	86.2%	63.7%
4168740	563.1.1.1 ↗	alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP	0.54	44.0	3.17e-01	94.8%	38.3%