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IMGVR_UViG_3300003830_000837-3300003830-Ga0051980_1000007411
Arc-VirIMGVR_UViG_3300003830_000837-3300003830-Ga0051980_1000007411
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-99
Domain cluster:
rep: peptidyl-tRNA_hydrolase__YP_009447948__Flamingopox_virus_FGPVKD09__2059380__D17-122
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1q7sA00 | 3.40.1490.10 | Alpha Beta › 3-Layer(aba) Sandwich › Bit1 › Bit1 | 0.77 | 71.0 | 6.71e-01 | 100.0% | 86.3% |
| 2gaxA00 | 3.40.1490.10 | Alpha Beta › 3-Layer(aba) Sandwich › Bit1 › Bit1 | 0.68 | 62.0 | 5.56e-01 | 100.0% | 85.8% |
| 1nbeB01 | 3.30.70.140 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aspartate carbamoyltransferase regulatory subunit, N-terminal domain | 0.61 | 32.0 | 3.36e-01 | 100.0% | 53.8% |
| 2ywwA01 | 3.30.70.140 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aspartate carbamoyltransferase regulatory subunit, N-terminal domain | 0.60 | 31.0 | 3.27e-01 | 100.0% | 53.8% |
| 2m71A00 | 3.30.110.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Translation initiation factor 3 (IF-3), C-terminal domain | 0.59 | 32.0 | 3.21e-01 | 99.0% | 50.0% |
| 2joqA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.57 | 31.0 | 3.44e-01 | 100.0% | 66.7% |
| 3drxB03 | 3.30.70.2000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 28.0 | 3.65e-01 | 100.0% | 88.2% |
| 3b8pA00 | 3.30.1890.10 | Alpha Beta › 2-Layer Sandwich › Bacterial polysaccharide co-polymerase-like › FepE-like | 0.56 | 50.0 | 3.94e-01 | 100.0% | 92.8% |
| 3jwhA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 44.0 | 3.58e-01 | 86.7% | 96.9% |
| 3c6kB03 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 38.0 | 3.11e-01 | 73.5% | 78.1% |
| 2p8jA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.52 | 38.0 | 3.09e-01 | 78.6% | 92.2% |
| 4xrpC01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.51 | 39.0 | 3.28e-01 | 81.6% | 98.9% |
| 3cb2A02 | 3.30.1330.20 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Tubulin/FtsZ, C-terminal domain | 0.51 | 31.0 | 3.10e-01 | 100.0% | 56.6% |
| 4lhpF00 | 3.30.429.10 | Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor | 0.51 | 45.0 | 4.14e-01 | 100.0% | 87.7% |
| 2aajA00 | 3.30.429.10 | Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor | 0.51 | 45.0 | 4.13e-01 | 100.0% | 88.4% |
| 4aq4A01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.51 | 41.0 | 3.37e-01 | 92.9% | 80.7% |
| 2wteA01 | 3.40.50.11700 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 42.0 | 3.78e-01 | 90.8% | 92.0% |
| 4l3nA02 | 2.20.210.30 | Mainly Beta › Single Sheet › ubp-family deubiquitinating enzyme fold › | 0.50 | 33.0 | 3.73e-01 | 100.0% | 97.0% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3990988 | 2501.1.1.1 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › PTH2 | 0.84 | 78.0 | 7.15e-01 | 100.0% | 89.5% |
| 3599010 | 2501.1.1.0 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II | 0.84 | 77.0 | 6.95e-01 | 99.0% | 90.8% |
| 4559979 | 2501.1.1.1 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › PTH2 | 0.84 | 78.0 | 7.22e-01 | 100.0% | 85.8% |
| 4946237 | 2501.1.1.1 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › PTH2 | 0.80 | 74.0 | 7.03e-01 | 100.0% | 87.8% |
| 4947020 | 2501.1.1.1 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › PTH2 | 0.80 | 74.0 | 6.97e-01 | 100.0% | 87.8% |
| 5030351 | 2501.1.1.1 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › PTH2 | 0.80 | 74.0 | 6.97e-01 | 100.0% | 87.0% |
| 3741182 | 2501.1.1.1 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › PTH2 | 0.79 | 73.0 | 6.40e-01 | 100.0% | 70.7% |
| 4025295 | 2501.1.1.1 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › PTH2 | 0.79 | 72.0 | 6.56e-01 | 100.0% | 86.0% |
| 3354413 | 2501.1.1.1 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › PTH2 | 0.78 | 72.0 | 6.73e-01 | 100.0% | 82.4% |
| 3595444 | 2501.1.1.0 ↗ | a/b three-layered sandwiches › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II › Peptidyl-tRNA hydrolase II | 0.78 | 71.0 | 6.36e-01 | 100.0% | 81.5% |
| 3587109 | 304.5.1.7 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 | 0.62 | 31.0 | 3.28e-01 | 100.0% | 51.1% |
| 3603235 | 242.1.1.2 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 | 0.61 | 34.0 | 3.43e-01 | 100.0% | 54.0% |
| 3590219 | 304.5.1.7 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 | 0.59 | 32.0 | 3.30e-01 | 100.0% | 53.3% |
| 3957946 | 256.1.1.12 ↗ | a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like › SOUL | 0.55 | 35.0 | 3.62e-01 | 100.0% | 68.9% |
| 3597858 | 2011.1.1.0 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases | 0.54 | 41.0 | 2.94e-01 | 82.7% | 89.2% |
| 5052400 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.53 | 37.0 | 2.99e-01 | 73.5% | 78.4% |
| 4011233 | 2002.1.1.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels | 0.53 | 43.0 | 3.14e-01 | 89.8% | 74.3% |
| 3274805 | 2003.1.5.67 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 | 0.52 | 40.0 | 3.06e-01 | 86.7% | 75.8% |
| 3387300 | 304.52.1.1 ↗ | a+b two layers › Alpha-beta plaits › YbeD/HP0495-like › YbeD/HP0495-like › DUF493 | 0.52 | 28.0 | 3.06e-01 | 100.0% | 62.5% |
D2
high
residues 101-154
Domain cluster:
representative
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2mh2A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.69 | 56.0 | 5.36e-01 | 94.4% | 78.1% |
| 3s93A00 | 3.30.420.610 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › LOTUS domain-like | 0.68 | 55.0 | 4.92e-01 | 92.6% | 87.5% |
| 3eyyA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.68 | 53.0 | 4.75e-01 | 100.0% | 59.8% |
| 4mtdD01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.66 | 53.0 | 4.68e-01 | 96.3% | 71.6% |
| 2fe3B01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.65 | 53.0 | 4.68e-01 | 94.4% | 60.0% |
| 2qbyB03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.64 | 50.0 | 4.43e-01 | 100.0% | 56.0% |
| 2cqnA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.64 | 55.0 | 4.98e-01 | 100.0% | 83.1% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.61 | 43.0 | 3.34e-01 | 77.8% | 62.0% |
| 1dxrL02 | 1.20.85.10 | Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like | 0.60 | 43.0 | 3.56e-01 | 79.6% | 39.8% |
| 6oinA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 49.0 | 4.69e-01 | 100.0% | 97.0% |
| 4eekA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.58 | 48.0 | 4.58e-01 | 96.3% | 90.9% |
| 2hszA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.57 | 47.0 | 4.31e-01 | 100.0% | 86.7% |
| 4wv4B00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.55 | 37.0 | 3.16e-01 | 70.4% | 43.0% |
| 4eqyA02 | 1.20.1180.10 | Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain | 0.55 | 42.0 | 3.95e-01 | 87.0% | 100.0% |
| 1fc6A01 | 3.30.750.44 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.53 | 41.0 | 3.39e-01 | 83.3% | 84.7% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.50 | 36.0 | 3.30e-01 | 81.5% | 84.0% |
| 3umgA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.50 | 42.0 | 3.87e-01 | 94.4% | 98.6% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3598925 | 1021.1.1.0 ↗ | a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases | 0.75 | 52.0 | 3.87e-01 | 77.8% | 30.0% |
| 4026717 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.74 | 60.0 | 5.62e-01 | 100.0% | 71.4% |
| 4928043 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.73 | 62.0 | 5.76e-01 | 98.1% | 94.3% |
| 3489868 | 101.1.1.4 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › PAX | 0.72 | 62.0 | 5.31e-01 | 100.0% | 63.3% |
| 3226857 | 101.1.1.4 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › PAX | 0.72 | 61.0 | 5.31e-01 | 98.1% | 62.4% |
| 3789626 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.72 | 61.0 | 5.79e-01 | 98.1% | 81.5% |
| 3884711 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.71 | 55.0 | 5.28e-01 | 96.3% | 73.8% |
| 3212935 | 101.1.1.4 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › PAX | 0.71 | 57.0 | 5.57e-01 | 90.7% | 83.3% |
| 3738343 | 101.1.1.79 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_ABP1_N | 0.70 | 59.0 | 5.81e-01 | 100.0% | 88.3% |
| 4014609 | 101.1.1.79 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_ABP1_N | 0.70 | 58.0 | 5.53e-01 | 100.0% | 80.0% |
| 3986794 | 639.2.1.1 ↗ | alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) › YmgB | 0.70 | 49.0 | 4.58e-01 | 75.9% | 80.0% |
| 3378866 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.69 | 53.0 | 5.16e-01 | 85.2% | 85.0% |
| 3419070 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.67 | 57.0 | 5.44e-01 | 100.0% | 90.8% |
| 3254663 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.67 | 53.0 | 4.93e-01 | 96.3% | 69.3% |
| 3589193 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.66 | 54.0 | 5.14e-01 | 94.4% | 83.1% |
| 3425084 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.66 | 55.0 | 4.69e-01 | 98.1% | 71.6% |
| 3234731 | 101.1.1.21 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 | 0.66 | 53.0 | 5.09e-01 | 94.4% | 86.2% |
| 4252854 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.66 | 55.0 | 5.06e-01 | 98.1% | 82.7% |
| 5023957 | 101.1.2.280 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_12 | 0.65 | 56.0 | 5.03e-01 | 100.0% | 91.3% |
| 5051575 | 2004.5.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain | 0.65 | 53.0 | 3.76e-01 | 94.4% | 29.4% |
| 4381449 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 53.0 | 5.02e-01 | 98.1% | 88.6% |
| 3185106 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 52.0 | 4.84e-01 | 96.3% | 76.0% |
| 3255275 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.65 | 51.0 | 5.04e-01 | 94.4% | 95.0% |
| 4380725 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.65 | 52.0 | 4.81e-01 | 98.1% | 70.7% |
| 4965761 | 101.1.2.925 ↗ | alpha arrays › HTH › HTH › winged helix domain › DUF7344 | 0.64 | 54.0 | 4.34e-01 | 100.0% | 69.6% |
| 3188664 | 101.1.2.306 ↗ | alpha arrays › HTH › HTH › winged helix domain › NPR2 | 0.63 | 52.0 | 5.18e-01 | 94.4% | 90.9% |
| 4976651 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 50.0 | 4.75e-01 | 100.0% | 75.7% |
| 3219370 | 198.1.1.1 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 | 0.62 | 52.0 | 4.68e-01 | 100.0% | 83.7% |
| 4014593 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.62 | 50.0 | 5.03e-01 | 98.1% | 100.0% |
| 4975514 | 7000.1.1.0 ↗ | alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS | 0.62 | 51.0 | 4.62e-01 | 100.0% | 91.3% |
| None | — | 0.61 | 51.0 | 3.28e-01 | 100.0% | 37.1% | |
| 3885572 | 108.1.1.19 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_3 | 0.57 | 43.0 | 3.60e-01 | 83.3% | 74.0% |
| 3714843 | 592.6.1.0 ↗ | alpha arrays › PWI domain-like › Pre-mRNA-splicing helicase BRR2 plug domain › Pre-mRNA-splicing helicase BRR2 plug domain | 0.56 | 45.0 | 3.87e-01 | 100.0% | 61.0% |
| 3725855 | 109.27.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain | 0.54 | 39.0 | 3.78e-01 | 100.0% | 69.2% |
| 4995782 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 44.0 | 4.10e-01 | 100.0% | 98.6% |
| 4984411 | 247.1.1.1 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B | 0.51 | 43.0 | 2.78e-01 | 100.0% | 29.5% |