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IMGVR_UViG_3300005095_000463-3300005095-Ga0072504_15646112
Arc-VirIMGVR_UViG_3300005095_000463-3300005095-Ga0072504_15646112
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-74_160-171
Domain cluster:
rep: IMGVR_UViG_3300014911_000395-3300014911-Ga0180301_100001548__D1-67
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3exzB00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.72 | 55.0 | 4.54e-01 | 80.2% | 93.2% |
| 4w78G00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.71 | 55.0 | 4.40e-01 | 81.4% | 98.2% |
| 4ffuB00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.71 | 53.0 | 4.37e-01 | 79.1% | 90.0% |
| 6jqlA03 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.67 | 49.0 | 3.90e-01 | 77.9% | 92.7% |
| 4e3eA00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.67 | 54.0 | 3.53e-01 | 86.0% | 60.7% |
| 1rerA01 | 2.60.98.10 | Mainly Beta › Sandwich › Tick-borne Encephalitis virus Glycoprotein; domain 1 › Tick-borne Encephalitis virus Glycoprotein, domain 1 | 0.67 | 55.0 | 4.82e-01 | 88.4% | 92.9% |
| 2gtlM02 | 2.40.128.620 | Mainly Beta › Beta Barrel › Lipocalin › | 0.66 | 57.0 | 4.62e-01 | 96.5% | 72.3% |
| 2bi0A01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.65 | 49.0 | 4.09e-01 | 80.2% | 92.8% |
| 1q6wG00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.65 | 47.0 | 3.96e-01 | 76.7% | 94.0% |
| 2gtlN02 | 2.40.128.620 | Mainly Beta › Beta Barrel › Lipocalin › | 0.65 | 56.0 | 4.55e-01 | 97.7% | 72.4% |
| 1ni9A01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.64 | 45.0 | 3.71e-01 | 79.1% | 41.1% |
| 1wpuA00 | 3.40.1510.10 | Alpha Beta › 3-Layer(aba) Sandwich › Hut operon positive regulatory protein HutP › Hut operon regulatory protein HutP | 0.64 | 47.0 | 4.02e-01 | 79.1% | 82.3% |
| 5aj3E01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.64 | 46.0 | 4.74e-01 | 76.7% | 80.2% |
| 3eyrA00 | 3.15.10.40 | Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Uncharacterised protein PF07273 family, DUF1439 | 0.63 | 49.0 | 4.03e-01 | 86.0% | 69.8% |
| 2nlkA02 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.62 | 39.0 | 2.85e-01 | 70.9% | 20.8% |
| 3hn3A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.61 | 43.0 | 4.09e-01 | 74.4% | 81.7% |
| 2w4yA00 | 2.40.160.220 | Mainly Beta › Beta Barrel › Porin › | 0.61 | 42.0 | 3.79e-01 | 73.3% | 73.0% |
| 4ccvA00 | 3.10.450.10 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.60 | 47.0 | 4.33e-01 | 84.9% | 73.9% |
| 7c5yA02 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.58 | 45.0 | 3.76e-01 | 83.7% | 95.4% |
| 3bf2A00 | 3.30.160.150 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain | 0.58 | 43.0 | 3.83e-01 | 79.1% | 82.4% |
| 2b1xB00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.58 | 44.0 | 3.69e-01 | 86.0% | 94.6% |
| 3a76A01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.58 | 43.0 | 3.75e-01 | 81.4% | 84.2% |
| 2n8xA00 | 3.30.160.150 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain | 0.58 | 43.0 | 3.52e-01 | 80.2% | 63.3% |
| 3m9qA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.57 | 40.0 | 4.34e-01 | 94.2% | 88.9% |
| 3d9rB00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.56 | 43.0 | 3.80e-01 | 83.7% | 91.0% |
| 1wnhA01 | 3.10.450.10 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 41.0 | 3.99e-01 | 81.4% | 78.0% |
| 4gn2A00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.55 | 44.0 | 3.24e-01 | 88.4% | 47.9% |
| 2k0rA00 | 2.60.40.1250 | Mainly Beta › Sandwich › Immunoglobulin-like › Thiol:disulfide interchange protein DsbD, N-terminal domain | 0.55 | 39.0 | 3.41e-01 | 74.4% | 75.8% |
| 3b8lA01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 42.0 | 3.65e-01 | 86.0% | 84.4% |
| 4cgyA03 | 2.70.20.10 | Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 | 0.54 | 39.0 | 3.40e-01 | 97.7% | 50.0% |
| 4cvuA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 39.0 | 3.55e-01 | 75.6% | 83.6% |
| 3f7xA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 41.0 | 3.56e-01 | 81.4% | 84.2% |
| 3soyA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 40.0 | 3.48e-01 | 81.4% | 81.7% |
| 3e99A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 42.0 | 3.60e-01 | 87.2% | 95.3% |
| 5tseA00 | 3.30.160.150 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain | 0.53 | 40.0 | 3.55e-01 | 82.6% | 77.2% |
| 3butA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 39.0 | 3.56e-01 | 80.2% | 84.0% |
| 4l8oA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 41.0 | 3.39e-01 | 84.9% | 75.0% |
| 2r4iA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 40.0 | 3.63e-01 | 82.6% | 89.4% |
| 3ulpD00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.53 | 40.0 | 3.70e-01 | 82.6% | 92.0% |
| 2w5nA00 | 2.120.10.10 | Mainly Beta › 6 Propeller › Neuraminidase › | 0.52 | 45.0 | 3.01e-01 | 97.7% | 88.8% |
| 4mlgG00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.52 | 46.0 | 3.16e-01 | 100.0% | 75.9% |
| 4binA01 | 2.60.40.3500 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.52 | 38.0 | 3.46e-01 | 76.7% | 66.4% |
| 2imjD01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 45.0 | 3.89e-01 | 100.0% | 94.4% |
| 3g3tA00 | 3.20.100.30 | Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › VTC, catalytic tunnel domain | 0.52 | 46.0 | 3.25e-01 | 100.0% | 85.4% |
| 2wliA02 | 2.60.40.1400 | Mainly Beta › Sandwich › Immunoglobulin-like › G protein-activated inward rectifier potassium channel 1 | 0.51 | 41.0 | 3.37e-01 | 88.4% | 98.1% |
| 2wllA02 | 2.60.40.1400 | Mainly Beta › Sandwich › Immunoglobulin-like › G protein-activated inward rectifier potassium channel 1 | 0.51 | 42.0 | 3.49e-01 | 88.4% | 100.0% |
| 4iupA02 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.51 | 36.0 | 3.87e-01 | 95.3% | 87.5% |
| 1olzA01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.50 | 42.0 | 2.74e-01 | 97.7% | 48.0% |
ECOD (68)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3735663 | 222.1.1.0 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase | 0.76 | 58.0 | 4.34e-01 | 81.4% | 68.3% |
| 3960891 | 222.1.1.9 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydrat_N | 0.74 | 57.0 | 4.57e-01 | 81.4% | 95.2% |
| 3693837 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.73 | 47.0 | 3.09e-01 | 70.9% | 16.1% |
| 3220105 | 2007.2.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase | 0.73 | 47.0 | 3.15e-01 | 75.6% | 17.8% |
| 1250095 | 222.1.1.1 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydratas | 0.73 | 55.0 | 4.49e-01 | 79.1% | 89.4% |
| 5072979 | 222.1.1.9 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydrat_N | 0.72 | 54.0 | 4.38e-01 | 77.9% | 97.4% |
| 3290304 | 222.1.1.1 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydratas | 0.71 | 54.0 | 4.39e-01 | 80.2% | 90.3% |
| 4962346 | 222.1.1.1 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydratas | 0.69 | 54.0 | 4.47e-01 | 83.7% | 94.7% |
| 1398172 | 222.1.1.9 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydrat_N | 0.68 | 55.0 | 4.30e-01 | 86.0% | 96.6% |
| 3840079 | 4998.1.1.1 ↗ | beta sandwiches › Flagellar hook protein flgE D2 domain-like › Flagellar hook protein flgE D2 domain › Flagellar hook protein flgE D2 domain › FlgE_D2 | 0.68 | 55.0 | 4.51e-01 | 86.0% | 76.7% |
| 3696814 | 222.1.1.0 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase | 0.68 | 52.0 | 3.86e-01 | 81.4% | 55.3% |
| 5075730 | 3435.1.1.0 ↗ | a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC | 0.67 | 47.0 | 4.29e-01 | 73.3% | 54.8% |
| 2527050 | 222.1.1.1 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydratas | 0.67 | 50.0 | 3.98e-01 | 80.2% | 93.8% |
| 3887954 | 10.1.1.72 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › CRLF3_C | 0.67 | 52.0 | 4.13e-01 | 83.7% | 77.0% |
| 3622962 | 331.3.1.17 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › VASt | 0.66 | 54.0 | 3.77e-01 | 86.0% | 59.6% |
| 861 | 9.3.1.3 ↗ | beta barrels › Lipocalins/Streptavidin › Quinohemoprotein amine dehydrogenase A chain, domain 3-like › Quinohemoprotein amine dehydrogenase A chain, domain 3-like › Eryth_link_C | 0.65 | 56.0 | 4.97e-01 | 97.7% | 96.1% |
| 3926039 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.65 | 50.0 | 4.76e-01 | 82.6% | 84.0% |
| 3785390 | 277.1.1.1 ↗ | a+b two layers › PX domain › PX domain › PX domain › PX | 0.64 | 49.0 | 4.28e-01 | 80.2% | 84.0% |
| 3251381 | 295.1.1.4 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › COMM_domain | 0.64 | 45.0 | 5.02e-01 | 83.7% | 96.9% |
| 3990957 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.63 | 46.0 | 3.86e-01 | 74.4% | 48.1% |
| 3605842 | 11.1.1.67 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF525 | 0.63 | 53.0 | 4.09e-01 | 89.5% | 75.7% |
| 137905 | 883.1.1.5 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › DUF1439 | 0.63 | 49.0 | 4.02e-01 | 86.0% | 69.6% |
| 4012567 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.63 | 51.0 | 4.00e-01 | 87.2% | 92.8% |
| 5009713 | 243.1.1.1 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › Ring_hydroxyl_B | 0.62 | 48.0 | 3.90e-01 | 81.4% | 85.6% |
| 3276225 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.62 | 44.0 | 4.04e-01 | 72.1% | 58.2% |
| 3291726 | 243.1.1.77 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF29518 | 0.62 | 47.0 | 3.91e-01 | 81.4% | 74.7% |
| 3290399 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.62 | 46.0 | 3.99e-01 | 80.2% | 78.4% |
| 3288890 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.62 | 45.0 | 4.02e-01 | 79.1% | 82.3% |
| 3959285 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.62 | 43.0 | 4.39e-01 | 72.1% | 79.8% |
| 3281675 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.61 | 43.0 | 4.04e-01 | 73.3% | 95.2% |
| 3957821 | 243.1.1.77 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF29518 | 0.61 | 48.0 | 4.24e-01 | 86.0% | 91.4% |
| 3703955 | 1100.1.1.1 ↗ | beta meanders › TIP41-like protein › TIP41-like protein › TIP41-like protein › TIP41 | 0.61 | 48.0 | 3.41e-01 | 84.9% | 51.9% |
| 3958465 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.60 | 45.0 | 3.84e-01 | 81.4% | 76.7% |
| 3925421 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.60 | 47.0 | 4.48e-01 | 83.7% | 84.0% |
| 4958928 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.60 | 46.0 | 4.23e-01 | 83.7% | 98.3% |
| 3934735 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.60 | 46.0 | 4.40e-01 | 82.6% | 84.0% |
| 5001466 | 2484.1.1.59 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA | 0.59 | 45.0 | 3.04e-01 | 81.4% | 38.8% |
| 3971296 | 243.1.1.5 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › Tim44 | 0.59 | 45.0 | 3.99e-01 | 83.7% | 86.0% |
| 4189419 | 243.1.1.77 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF29518 | 0.59 | 46.0 | 3.81e-01 | 83.7% | 73.3% |
| 3958251 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.58 | 45.0 | 3.83e-01 | 86.0% | 76.0% |
| 3959534 | 243.1.1.77 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF29518 | 0.58 | 44.0 | 3.90e-01 | 83.7% | 83.7% |
| 3404065 | 295.1.1.4 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › COMM_domain | 0.58 | 40.0 | 4.18e-01 | 72.1% | 88.7% |
| 3829251 | 9.1.1.34 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › PAP_fibrillin | 0.58 | 50.0 | 4.03e-01 | 98.8% | 86.9% |
| 3651800 | 71.1.1.12 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › DUF620 | 0.57 | 44.0 | 3.70e-01 | 81.4% | 81.4% |
| 3860882 | 11.1.1.1025 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF4556 | 0.57 | 41.0 | 3.84e-01 | 75.6% | 91.8% |
| 3724449 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.57 | 40.0 | 4.01e-01 | 73.3% | 75.6% |
| 3515333 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.56 | 43.0 | 4.30e-01 | 84.9% | 90.0% |
| 3423922 | 243.3.1.19 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF3615 | 0.56 | 43.0 | 4.02e-01 | 86.0% | 69.3% |
| 3663259 | 881.1.1.1 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › PsbP | 0.56 | 41.0 | 3.64e-01 | 82.6% | 51.1% |
| 3715923 | 5.1.3.28 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › BNR_3 | 0.55 | 48.0 | 3.07e-01 | 96.5% | 81.4% |
| 3581448 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.55 | 41.0 | 3.84e-01 | 82.6% | 69.6% |
| 3646327 | 9.1.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins | 0.55 | 47.0 | 3.85e-01 | 95.3% | 78.1% |
| 5035197 | 4252.1.1.0 ↗ | beta barrels › AttH-like › AttH-like › AttH-like | 0.54 | 46.0 | 3.81e-01 | 97.7% | 98.8% |
| 3334482 | 9.23.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Hypothetical protein BT_0869 › Hypothetical protein BT_0869 › PAP_fibrillin | 0.54 | 47.0 | 3.74e-01 | 96.5% | 78.3% |
| 3930653 | 243.3.1.1 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › Cystatin | 0.53 | 41.0 | 4.08e-01 | 84.9% | 88.9% |
| 4847872 | 230.1.1.5 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 | 0.53 | 38.0 | 3.51e-01 | 75.6% | 91.4% |
| 4951664 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.53 | 43.0 | 3.59e-01 | 88.4% | 59.3% |
| 3829111 | 881.1.1.1 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › PsbP | 0.53 | 40.0 | 3.05e-01 | 81.4% | 36.2% |
| 3591306 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.53 | 40.0 | 4.34e-01 | 96.5% | 98.6% |
| 3764790 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.53 | 39.0 | 3.81e-01 | 80.2% | 73.7% |
| 3464474 | 264.2.1.0 ↗ | beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain | 0.52 | 39.0 | 3.30e-01 | 81.4% | 87.7% |
| 3921426 | 264.2.1.1 ↗ | beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac | 0.52 | 39.0 | 3.41e-01 | 100.0% | 52.3% |
| 3433312 | 264.2.1.0 ↗ | beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain | 0.52 | 38.0 | 3.35e-01 | 98.8% | 52.0% |
| 3707878 | 5.1.2.33 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › BNR_3 | 0.52 | 44.0 | 3.12e-01 | 95.3% | 82.5% |
| 3786448 | 5.1.4.242 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PEP5_VPS11_N | 0.51 | 41.0 | 2.70e-01 | 87.2% | 23.5% |
| 3177804 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.51 | 40.0 | 3.37e-01 | 88.4% | 64.4% |
| 4056691 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.51 | 36.0 | 3.23e-01 | 74.4% | 55.0% |
| 3881440 | 264.2.1.0 ↗ | beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain | 0.50 | 38.0 | 3.39e-01 | 81.4% | 86.4% |
D2
medium
residues 75-159
Domain cluster:
representative
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ljlA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.67 | 46.0 | 3.87e-01 | 88.2% | 41.6% |
| 1ailA00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.66 | 49.0 | 5.22e-01 | 83.5% | 95.7% |
| 3szpA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 49.0 | 4.83e-01 | 83.5% | 88.8% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.62 | 38.0 | 3.48e-01 | 98.8% | 46.5% |
| 4zo4A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 54.0 | 4.04e-01 | 94.1% | 86.6% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 40.0 | 4.28e-01 | 100.0% | 77.0% |
| 2e9xD01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 42.0 | 3.56e-01 | 72.9% | 48.9% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.58 | 40.0 | 3.48e-01 | 70.6% | 69.5% |
| 3t0yA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 39.0 | 4.58e-01 | 95.3% | 100.0% |
| 4gyvE00 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.56 | 40.0 | 3.02e-01 | 75.3% | 80.9% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.56 | 38.0 | 4.26e-01 | 100.0% | 92.2% |
| 3hhcC00 | 1.20.1250.60 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda | 0.55 | 49.0 | 4.06e-01 | 98.8% | 66.9% |
| 3p7nA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 40.0 | 4.23e-01 | 82.4% | 91.7% |
| 6jqsA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 40.0 | 4.36e-01 | 83.5% | 100.0% |
| 1gpjA03 | 1.10.1200.70 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glutamyl tRNA-reductase dimerization domain | 0.55 | 37.0 | 3.77e-01 | 70.6% | 81.2% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 38.0 | 3.65e-01 | 72.9% | 77.6% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.54 | 38.0 | 3.52e-01 | 100.0% | 56.2% |
| 7sgrA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.54 | 42.0 | 2.91e-01 | 83.5% | 41.6% |
| 1lb3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 41.0 | 3.31e-01 | 82.4% | 41.3% |
| 4gouA03 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.54 | 38.0 | 2.95e-01 | 74.1% | 62.9% |
| 2uv8A07 | 6.10.140.1410 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 35.0 | 3.52e-01 | 98.8% | 65.9% |
| 4pxoA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 38.0 | 3.32e-01 | 74.1% | 93.1% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 48.0 | 3.55e-01 | 100.0% | 93.1% |
| 4a4kA01 | 1.20.1500.20 | Mainly Alpha › Up-down Bundle › YheA-like fold › | 0.54 | 40.0 | 3.76e-01 | 82.4% | 67.3% |
| 1rykA00 | 1.10.1470.10 | Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › YjbJ | 0.53 | 34.0 | 3.79e-01 | 85.9% | 81.2% |
| 5xsoA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 39.0 | 4.11e-01 | 82.4% | 92.1% |
| 2w7nA00 | 1.10.10.2690 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.53 | 35.0 | 3.46e-01 | 91.8% | 62.8% |
| 4xaxB02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.53 | 40.0 | 3.79e-01 | 80.0% | 94.9% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.52 | 38.0 | 4.07e-01 | 100.0% | 90.4% |
| 3q23A08 | 1.20.140.110 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.52 | 43.0 | 3.61e-01 | 92.9% | 94.2% |
| 2id6A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 43.0 | 3.59e-01 | 92.9% | 63.6% |
| 3pivA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 41.0 | 3.47e-01 | 89.4% | 54.5% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.52 | 34.0 | 3.44e-01 | 98.8% | 66.7% |
| 2cfqA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 41.0 | 3.11e-01 | 85.9% | 79.5% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.52 | 42.0 | 2.74e-01 | 90.6% | 66.6% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 38.0 | 3.65e-01 | 78.8% | 93.1% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 39.0 | 3.11e-01 | 84.7% | 80.7% |
| 5u1aL00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 40.0 | 3.25e-01 | 85.9% | 63.9% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3611154 | 109.1.1.16 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_6 | 0.69 | 58.0 | 4.68e-01 | 95.3% | 83.5% |
| 3954536 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 51.0 | 4.58e-01 | 85.9% | 63.3% |
| 4996069 | 604.10.1.0 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac | 0.60 | 41.0 | 4.08e-01 | 70.6% | 74.4% |
| 3399352 | 5067.1.1.5 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing | 0.60 | 42.0 | 3.04e-01 | 72.9% | 45.5% |
| 3508392 | 604.6.1.32 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › Mito_morph_reg | 0.60 | 41.0 | 3.66e-01 | 71.8% | 78.2% |
| 3941601 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 44.0 | 3.39e-01 | 78.8% | 87.0% |
| 4016292 | 192.2.1.18 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING | 0.58 | 40.0 | 3.41e-01 | 98.8% | 44.4% |
| 3969666 | 101.1.2.1 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_1 | 0.58 | 47.0 | 4.68e-01 | 90.6% | 94.4% |
| 4016436 | 3324.1.1.1 ↗ | extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › MTR4_beta-barrel | 0.58 | 44.0 | 4.13e-01 | 82.4% | 66.4% |
| 4092649 | 5050.1.1.32 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Acatn | 0.58 | 41.0 | 3.23e-01 | 76.5% | 90.5% |
| 3727173 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.58 | 41.0 | 2.60e-01 | 75.3% | 24.8% |
| 4928757 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.57 | 45.0 | 3.67e-01 | 87.1% | 48.2% |
| 3478267 | 3812.1.1.0 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE | 0.57 | 40.0 | 4.29e-01 | 75.3% | 84.0% |
| 4118534 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.57 | 45.0 | 2.81e-01 | 88.2% | 14.7% |
| 3424723 | 141.1.1.3 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA | 0.57 | 46.0 | 3.26e-01 | 94.1% | 89.6% |
| 3508723 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.56 | 41.0 | 3.67e-01 | 78.8% | 53.6% |
| 3971977 | 101.1.3.0 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like | 0.56 | 43.0 | 4.39e-01 | 83.5% | 95.0% |
| 5032080 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 43.0 | 3.96e-01 | 88.2% | 96.5% |
| 4395758 | 101.1.3.1 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE | 0.54 | 41.0 | 4.27e-01 | 83.5% | 88.7% |
| 4360664 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 48.0 | 3.57e-01 | 100.0% | 82.7% |
| 3962431 | 101.1.3.0 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like | 0.54 | 40.0 | 4.18e-01 | 85.9% | 90.7% |
| 5047946 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 47.0 | 3.53e-01 | 100.0% | 85.0% |
| 3945219 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.53 | 41.0 | 3.87e-01 | 85.9% | 70.0% |
| 3187948 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 40.0 | 3.13e-01 | 82.4% | 69.1% |
| 4023387 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.53 | 40.0 | 3.81e-01 | 80.0% | 77.0% |
| 4300897 | 5094.1.1.1 ↗ | a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH | 0.52 | 39.0 | 3.33e-01 | 100.0% | 50.0% |
| 4890627 | 603.8.1.1 ↗ | alpha bundles › STAT-like › Alpha-ketoglutarate-dependent dioxygenase FTO helical domain › Alpha-ketoglutarate-dependent dioxygenase FTO helical domain › FTO_CTD | 0.52 | 39.0 | 3.41e-01 | 78.8% | 66.9% |
| 5048096 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.52 | 38.0 | 3.28e-01 | 75.3% | 59.2% |
| 3468090 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.52 | 38.0 | 3.47e-01 | 100.0% | 57.4% |
| 3509240 | 101.1.1.24 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › CENP-B_N | 0.52 | 33.0 | 3.63e-01 | 90.6% | 84.6% |
| 3289545 | 150.8.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE | 0.52 | 36.0 | 2.78e-01 | 71.8% | 61.1% |
| 3286659 | 101.1.3.1 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE | 0.51 | 38.0 | 4.10e-01 | 84.7% | 100.0% |
| 4961716 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 43.0 | 3.37e-01 | 96.5% | 97.9% |
| 4071531 | 1188.1.1.3 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp | 0.51 | 39.0 | 3.10e-01 | 84.7% | 76.8% |
| 3345803 | 143.1.1.0 ↗ | alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain | 0.51 | 39.0 | 3.95e-01 | 82.4% | 98.8% |
| 5079046 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.51 | 45.0 | 3.90e-01 | 100.0% | 94.8% |
| 3563670 | 3758.1.1.54 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › ApoL | 0.50 | 42.0 | 4.20e-01 | 100.0% | 86.7% |