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IMGVR_UViG_3300005099_000193-3300005099-Ga0072682_1022089
Arc-VirIMGVR_UViG_3300005099_000193-3300005099-Ga0072682_1022089
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 28-116
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qw6D00 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.92 | 81.0 | 8.31e-01 | 98.9% | 96.5% |
| 3u61D03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.77 | 67.0 | 6.67e-01 | 100.0% | 92.3% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.73 | 60.0 | 5.26e-01 | 89.9% | 78.9% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.71 | 57.0 | 5.16e-01 | 88.8% | 92.7% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 58.0 | 5.32e-01 | 92.1% | 99.1% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 54.0 | 4.91e-01 | 89.9% | 98.3% |
| 1vkeB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.66 | 50.0 | 4.78e-01 | 85.4% | 70.3% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.64 | 51.0 | 4.39e-01 | 86.5% | 92.4% |
| 2a0bA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.63 | 49.0 | 4.54e-01 | 88.8% | 64.4% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.63 | 50.0 | 5.20e-01 | 89.9% | 94.0% |
| 2katA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 45.0 | 4.19e-01 | 78.7% | 59.1% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.62 | 49.0 | 4.29e-01 | 86.5% | 92.8% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.62 | 49.0 | 4.74e-01 | 88.8% | 77.0% |
| 7kb2B01 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.59 | 42.0 | 3.40e-01 | 75.3% | 60.5% |
| 3mkqA03 | 1.25.40.470 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 38.0 | 2.93e-01 | 74.2% | 27.4% |
| 4y6cA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 43.0 | 3.34e-01 | 78.7% | 37.7% |
| 3rjvA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 39.0 | 3.41e-01 | 75.3% | 42.4% |
| 7xcnM01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.58 | 47.0 | 4.99e-01 | 92.1% | 98.7% |
| 2r5sA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 41.0 | 4.16e-01 | 75.3% | 78.4% |
| 3qwwA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 41.0 | 3.26e-01 | 77.5% | 38.7% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.56 | 48.0 | 4.46e-01 | 93.3% | 84.5% |
| 2i2xB01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.56 | 44.0 | 4.28e-01 | 85.4% | 80.0% |
| 7wf8B01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.55 | 44.0 | 4.07e-01 | 89.9% | 69.4% |
| 3eslA02 | 1.25.40.930 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 46.0 | 4.26e-01 | 95.5% | 89.9% |
| 5c4yA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 48.0 | 4.22e-01 | 100.0% | 89.7% |
| 2wglA00 | 1.10.4190.10 | Mainly Alpha › Orthogonal Bundle › Urease accessory protein UreF › Urease accessory protein UreF | 0.54 | 44.0 | 3.45e-01 | 92.1% | 95.7% |
| 3fp3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 38.0 | 3.40e-01 | 78.7% | 49.6% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 40.0 | 3.42e-01 | 80.9% | 69.3% |
| 2kj8A00 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.52 | 39.0 | 3.58e-01 | 95.5% | 60.2% |
| 2c0gA02 | 1.20.1150.12 | Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain | 0.52 | 39.0 | 3.72e-01 | 80.9% | 86.8% |
| 3k9iA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 42.0 | 4.04e-01 | 88.8% | 80.6% |
| 7qihA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 42.0 | 4.06e-01 | 93.3% | 77.2% |
| 2ja2A05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.51 | 39.0 | 3.82e-01 | 100.0% | 74.5% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3515673 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.75 | 68.0 | 6.65e-01 | 100.0% | 93.7% |
| 5044963 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.72 | 59.0 | 5.09e-01 | 88.8% | 67.9% |
| 4951139 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 59.0 | 5.67e-01 | 89.9% | 87.0% |
| 5040635 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.70 | 55.0 | 5.09e-01 | 85.4% | 93.9% |
| 5072210 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.68 | 55.0 | 5.66e-01 | 89.9% | 92.9% |
| 4965663 | 5039.1.1.1 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 | 0.67 | 53.0 | 3.87e-01 | 87.6% | 54.2% |
| 3785546 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.65 | 53.0 | 4.61e-01 | 89.9% | 77.9% |
| 3387089 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.65 | 48.0 | 3.36e-01 | 79.8% | 94.4% |
| 3171602 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 54.0 | 4.71e-01 | 94.4% | 90.0% |
| 4034578 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.64 | 53.0 | 4.74e-01 | 93.3% | 93.1% |
| 5044891 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 55.0 | 3.65e-01 | 100.0% | 70.8% |
| 3953082 | 601.7.1.34 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 | 0.61 | 52.0 | 5.07e-01 | 95.5% | 100.0% |
| 5008560 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.61 | 50.0 | 4.75e-01 | 89.9% | 74.3% |
| 4962588 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.60 | 53.0 | 3.98e-01 | 100.0% | 69.8% |
| 3016134 | 109.4.1.212 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_20 | 0.59 | 42.0 | 4.26e-01 | 75.3% | 78.4% |
| 3868941 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.59 | 49.0 | 3.93e-01 | 92.1% | 65.7% |
| 3560923 | 109.4.1.1411 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30303 | 0.58 | 42.0 | 3.94e-01 | 75.3% | 67.3% |
| 3273679 | 207.1.1.1 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1 | 0.58 | 48.0 | 3.82e-01 | 88.8% | 54.3% |
| 5050100 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.58 | 42.0 | 3.74e-01 | 77.5% | 56.3% |
| 5062133 | 101.1.2.135 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR_2 | 0.58 | 46.0 | 3.26e-01 | 87.6% | 33.0% |
| 5057941 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.57 | 42.0 | 3.46e-01 | 78.7% | 70.0% |
| 3714893 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 39.0 | 3.25e-01 | 76.4% | 38.8% |
| 3304974 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.54 | 42.0 | 3.08e-01 | 87.6% | 61.8% |
| 3385850 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.54 | 45.0 | 3.40e-01 | 95.5% | 65.5% |
| 4411218 | 172.2.1.1 ↗ | alpha complex topology › Citrate synthase-like › Urease accessory protein ureF › Urease accessory protein ureF › UreF | 0.53 | 42.0 | 3.21e-01 | 87.6% | 68.4% |
| 4025215 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 38.0 | 2.81e-01 | 74.2% | 40.4% |
| 3385165 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.53 | 46.0 | 3.44e-01 | 96.6% | 38.6% |
| 3682981 | 109.4.1.1260 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, PPR_long | 0.52 | 45.0 | 2.77e-01 | 97.8% | 15.6% |
| 4020688 | 610.1.1.0 ↗ | alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like | 0.51 | 39.0 | 3.85e-01 | 84.3% | 89.0% |
| 4306436 | 610.1.1.1 ↗ | alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like › ERp29 | 0.51 | 39.0 | 3.73e-01 | 84.3% | 85.2% |
| 3932321 | 109.46.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) | 0.51 | 42.0 | 3.89e-01 | 96.6% | 72.0% |
D2
high
residues 142-198
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tmxB00 | 2.60.130.10 | Mainly Beta › Sandwich › Protocatechuate 3,4-Dioxygenase, subunit A › Aromatic compound dioxygenase | 0.67 | 45.0 | 2.88e-01 | 75.4% | 13.9% |
| 3vouB00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 49.0 | 3.76e-01 | 84.2% | 61.0% |
| 2ivxB01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.63 | 51.0 | 3.88e-01 | 91.2% | 72.9% |
| 4bzaA01 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.62 | 41.0 | 3.87e-01 | 70.2% | 55.9% |
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.61 | 50.0 | 4.87e-01 | 91.2% | 85.7% |
| 1j3wC00 | 3.30.450.30 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic | 0.60 | 44.0 | 3.43e-01 | 80.7% | 97.7% |
| 7e84A03 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 43.0 | 3.44e-01 | 80.7% | 61.0% |
| 4epzA00 | 1.25.40.810 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ | 0.59 | 48.0 | 3.53e-01 | 91.2% | 57.1% |
| 2c35A00 | 1.20.1250.40 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › RNA Polymerase II, Rpb4 subunit | 0.57 | 44.0 | 3.56e-01 | 91.2% | 85.9% |
| 2b3wA00 | 1.10.357.40 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › YbiA-like | 0.54 | 43.0 | 3.16e-01 | 91.2% | 42.3% |
| 2ndpA00 | 4.10.520.10 | Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins | 0.52 | 36.0 | 3.06e-01 | 100.0% | 41.4% |