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IMGVR_UViG_3300005263_000067-3300005263-Ga0071346_10095019

Arc-Vir

Identity

Accession:: IMGVR_UViG_3300005263_000067-3300005263-Ga0071346_10095019 ↗
Kingdom:: archaea

Quality

86.4 mean pLDDT

Cluster

View cluster (8 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 263-358

PDB

Domain cluster: representative

CATH (19)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3m1mA03	1.10.1240.50	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 ›	0.67	51.0	4.93e-01	82.3%	87.3%
3ztaA00	1.10.490.130	Mainly Alpha › Orthogonal Bundle › Globin-like ›	0.67	49.0	4.38e-01	78.1%	77.0%
1pbwB00	1.10.555.10	Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein	0.65	49.0	3.95e-01	81.2%	81.0%
5ctrA01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.63	45.0	3.20e-01	79.2%	23.6%
8alzB08	1.10.3380.10	Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain	0.61	43.0	3.88e-01	71.9%	98.5%
2olpA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.60	46.0	3.99e-01	81.2%	71.5%
2zs0A00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.59	43.0	3.85e-01	78.1%	69.3%
1txuA02	1.20.1050.80	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › VPS9 domain	0.59	42.0	3.58e-01	75.0%	59.4%
1yozA00	1.10.3200.10	Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like	0.58	41.0	3.95e-01	75.0%	98.2%
1y14A01	1.20.1250.40	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › RNA Polymerase II, Rpb4 subunit	0.57	34.0	3.16e-01	78.1%	44.5%
6mh4A03	1.10.1740.10	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif	0.57	36.0	3.91e-01	80.2%	77.2%
4yvoA00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.57	40.0	3.74e-01	72.9%	59.7%
6n2nA01	3.40.920.10	Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	0.56	43.0	3.53e-01	82.3%	100.0%
4iluA02	1.20.58.1290	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain	0.55	42.0	4.05e-01	81.2%	73.0%
1v9mA03	1.20.1690.10	Mainly Alpha › Up-down Bundle › V-type ATP synthase subunit C fold › V-type ATP synthase subunit C domain	0.55	40.0	4.10e-01	79.2%	88.5%
6xssA01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.54	34.0	3.79e-01	74.0%	87.0%
1gcvA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.53	41.0	3.65e-01	81.2%	68.6%
4f0uA00	1.10.490.20	Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins	0.53	37.0	3.25e-01	74.0%	58.1%
5um2A02	3.40.190.10	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II	0.52	44.0	3.74e-01	92.7%	65.6%

ECOD (24)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5064030	182.1.3.0 ↗	alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX	0.89	82.0	8.30e-01	97.9%	98.9%
5081313	182.1.3.0 ↗	alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX	0.82	69.0	7.17e-01	93.8%	96.7%
3586830	182.1.3.2 ↗	alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › PriCT_1	0.81	75.0	7.06e-01	100.0%	93.0%
5058298	182.1.3.0 ↗	alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX	0.81	75.0	6.97e-01	100.0%	84.7%
4973692	182.1.3.0 ↗	alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX	0.81	73.0	7.27e-01	97.9%	100.0%
5030284	182.1.3.3 ↗	alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg	0.80	72.0	6.68e-01	97.9%	87.5%
5039859	6035.1.1.0 ↗	alpha bundles › Primase helical domain › Primase helical domain › Primase helical domain	0.72	55.0	5.71e-01	80.2%	88.9%
4354447	1197.1.1.1 ↗	alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf	0.69	49.0	3.93e-01	72.9%	62.2%
3638575	109.3.1.170 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_4	0.66	50.0	3.71e-01	81.2%	78.8%
3407843	197.1.1.0 ↗	alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like	0.66	56.0	5.14e-01	93.8%	89.6%
3960236	106.1.1.11 ↗	alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N	0.65	49.0	4.32e-01	81.2%	73.1%
3576491	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.61	44.0	4.63e-01	77.1%	97.6%
4946543	2004.1.3.3 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR_N	0.60	46.0	3.65e-01	82.3%	94.4%
4242672	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.59	46.0	3.62e-01	83.3%	58.0%
3447336	109.4.1.1207 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TmcB	0.58	38.0	3.54e-01	76.0%	52.5%
4984123	131.1.1.3 ↗	alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD	0.57	42.0	3.50e-01	80.2%	61.1%
5079962	601.28.1.4 ↗	alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › DUF4129	0.56	40.0	3.83e-01	72.9%	96.4%
3248745	627.1.1.1 ↗	alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9	0.56	41.0	3.58e-01	76.0%	56.6%
3842854	109.4.1.343 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RAB3GAP2_C	0.56	39.0	3.22e-01	74.0%	46.3%
3371226	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.56	42.0	3.49e-01	80.2%	55.3%
3883914	101.1.10.0 ↗	alpha arrays › HTH › HTH › Cyclin-like	0.55	39.0	3.79e-01	75.0%	88.1%
3566734	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.54	45.0	3.53e-01	96.9%	54.8%
3788328	138.1.1.0 ↗	alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain	0.52	42.0	3.83e-01	89.6%	70.0%
4277995	628.1.1.1 ↗	alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD	0.50	37.0	3.21e-01	78.1%	60.6%

D2 high residues 363-451

PDB

Domain cluster: representative

CATH (38)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3tp3A02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.73	61.0	5.19e-01	93.3%	79.7%
1uurA01	1.20.58.240	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1	0.69	55.0	5.11e-01	85.4%	98.2%
3frqB00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.68	59.0	4.70e-01	97.8%	70.7%
1dgfA03	1.20.1370.60	Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain ›	0.67	55.0	5.06e-01	88.8%	82.5%
1i6zA00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.66	52.0	4.58e-01	86.5%	81.5%
3h20A04	1.10.1240.50	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 ›	0.66	50.0	5.10e-01	83.1%	83.1%
2d2sA01	1.20.58.1210	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain	0.65	42.0	3.92e-01	80.9%	50.9%
2id3A02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.64	51.0	4.47e-01	89.9%	79.6%
2lvfA00	1.10.110.10	Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins	0.64	52.0	4.88e-01	92.1%	86.8%
1bf5A01	1.20.1050.20	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain	0.63	53.0	4.38e-01	94.4%	90.5%
3sqiA01	1.10.150.540	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 ›	0.63	49.0	4.80e-01	84.3%	76.8%
3l09A01	1.20.58.1460	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.63	47.0	4.57e-01	79.8%	84.7%
4cqiA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.63	43.0	4.06e-01	70.8%	100.0%
1r9dA01	3.20.70.20	Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain ›	0.61	55.0	3.21e-01	100.0%	69.3%
2hyjA02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.61	52.0	4.54e-01	100.0%	81.0%
3hhsA01	1.20.1370.10	Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › Hemocyanin, N-terminal domain	0.59	46.0	3.95e-01	84.3%	52.4%
3pasA00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.58	47.0	3.87e-01	94.4%	73.2%
5z9iA00	1.10.630.10	Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450	0.57	47.0	3.18e-01	93.3%	79.0%
4agsA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.57	47.0	4.18e-01	93.3%	71.9%
3t6gB00	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.57	46.0	4.08e-01	88.8%	83.6%
1ya0A01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.57	50.0	3.86e-01	98.9%	53.4%
1svmA02	1.20.1050.70	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3	0.57	46.0	4.20e-01	88.8%	92.4%
8b70A01	1.20.1740.10	Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I	0.57	50.0	3.27e-01	100.0%	87.1%
3kyiA00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.56	44.0	3.94e-01	85.4%	100.0%
4l7mA00	1.25.10.10	Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant	0.56	41.0	3.04e-01	80.9%	28.0%
3pvlA03	1.20.80.10	Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein ›	0.54	44.0	4.07e-01	91.0%	71.2%
2f2cA02	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.54	39.0	3.73e-01	77.5%	77.4%
5dvwA00	1.20.120.1160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.54	41.0	3.62e-01	85.4%	55.3%
4cybD00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.53	45.0	3.65e-01	93.3%	86.5%
6srbA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.53	47.0	4.41e-01	98.9%	87.2%
5hayA02	1.25.40.440	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain	0.53	36.0	3.80e-01	76.4%	79.7%
1oahA02	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.53	40.0	3.41e-01	79.8%	95.8%
3dwlG00	1.25.40.190	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5	0.53	40.0	3.71e-01	86.5%	63.2%
1u89A00	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.53	38.0	3.41e-01	78.7%	63.3%
1f5qB02	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.53	36.0	3.20e-01	71.9%	82.6%
2fonA04	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.52	43.0	3.85e-01	96.6%	63.6%
1g3nC01	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.51	37.0	3.35e-01	76.4%	94.2%
4xchA00	3.30.1360.80	Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › S-ribosylhomocysteinase (LuxS)	0.50	35.0	2.99e-01	73.0%	71.8%

ECOD (39)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5022018	4973.1.1.0 ↗	alpha bundles › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core	0.88	66.0	7.38e-01	78.7%	100.0%
5003619	4973.1.1.0 ↗	alpha bundles › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core	0.87	62.0	7.12e-01	75.3%	100.0%
5070078	1075.1.1.3 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2	0.77	68.0	4.93e-01	96.6%	54.8%
3269361	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.76	61.0	4.60e-01	86.5%	43.3%
4046675	4973.1.1.1 ↗	alpha bundles › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › helical domain in DNA primase DnaG catalytic core › DnaB_bind	0.74	55.0	5.62e-01	78.7%	81.2%
4249392	195.1.1.1 ↗	alpha complex topology › NusB-like › NusB-like › NusB-like › NusB	0.72	52.0	4.62e-01	76.4%	100.0%
5042310	195.1.1.1 ↗	alpha complex topology › NusB-like › NusB-like › NusB-like › NusB	0.71	51.0	4.44e-01	75.3%	90.4%
4848262	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.70	43.0	4.07e-01	98.9%	51.4%
4034377	4982.1.1.2 ↗	alpha arrays › KaiA/RbsU domain-like › KaiA/RbsU domain › KaiA/RbsU domain › RsbU_N	0.69	58.0	5.79e-01	89.9%	100.0%
4413687	195.1.1.1 ↗	alpha complex topology › NusB-like › NusB-like › NusB-like › NusB	0.68	50.0	4.15e-01	76.4%	87.6%
5044572	310.2.1.0 ↗	a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF	0.67	51.0	4.86e-01	80.9%	100.0%
3172034	1065.1.1.1 ↗	alpha bundles › SPX domain › SPX domain › SPX domain › SPX	0.67	52.0	4.15e-01	85.4%	69.7%
4959408	1075.1.1.38 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › FLQE3_permease	0.64	55.0	4.14e-01	96.6%	51.7%
3758972	604.1.1.1 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin	0.64	50.0	4.71e-01	85.4%	96.4%
3218650	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.63	50.0	4.75e-01	85.4%	100.0%
1546400	186.1.1.0 ↗	alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N	0.63	49.0	4.81e-01	84.3%	77.6%
3597417	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.63	51.0	3.29e-01	91.0%	20.9%
3391380	604.12.1.0 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain	0.62	49.0	4.68e-01	85.4%	97.1%
3734968	3745.1.1.1 ↗	alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex	0.62	52.0	3.57e-01	95.5%	75.8%
3376799	109.4.1.18 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPTA	0.62	47.0	3.06e-01	83.1%	17.6%
4022845	1065.1.1.1 ↗	alpha bundles › SPX domain › SPX domain › SPX domain › SPX	0.62	54.0	4.12e-01	100.0%	85.0%
5034208	310.2.1.0 ↗	a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF	0.62	53.0	4.67e-01	97.8%	100.0%
4420971	109.25.1.1 ↗	alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN	0.62	45.0	4.09e-01	78.7%	73.6%
3246569	109.4.1.1224 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_DOCK9	0.61	49.0	3.50e-01	91.0%	31.1%
3471396	604.6.1.0 ↗	alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain	0.61	47.0	4.60e-01	82.0%	98.9%
3186931	603.1.1.5 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N	0.60	51.0	4.12e-01	97.8%	85.3%
3860700	109.25.1.1 ↗	alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN	0.60	45.0	4.14e-01	80.9%	71.7%
3650037	604.1.1.127 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4	0.60	46.0	4.20e-01	84.3%	84.0%
3931714	3826.1.1.46 ↗	alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › L27_1	0.59	38.0	3.89e-01	98.9%	67.1%
5051430	632.1.1.2 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › BE_C	0.59	38.0	3.44e-01	71.9%	48.3%
3524429	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.59	45.0	4.41e-01	84.3%	98.0%
4075843	185.1.1.1 ↗	alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Tryp_alpha_amyl	0.58	47.0	4.47e-01	87.6%	88.5%
3506862	611.3.1.0 ↗	alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	0.57	42.0	4.41e-01	79.8%	93.8%
3879191	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.57	40.0	3.61e-01	77.5%	50.8%
3642421	603.1.1.5 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N	0.55	46.0	4.13e-01	92.1%	87.2%
1320273	101.1.10.11 ↗	alpha arrays › HTH › HTH › Cyclin-like › Herp-Cyclin	0.53	39.0	3.66e-01	77.5%	75.2%
3712353	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	39.0	3.07e-01	85.4%	45.6%
3975686	6050.1.1.2 ↗	a+b two layers › Phage tail assembly chaperone › Phage tail assembly chaperone › Phage tail assembly chaperone › Phage_TAC_2	0.51	43.0	4.09e-01	93.3%	77.1%
5012500	3843.1.1.6 ↗	alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF	0.51	42.0	4.29e-01	95.5%	92.9%

D3 high residues 621-768_813-826

PDB

Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF19263.6 best	DUF5906	60.8	2.70e-16	70.4%	100.0%

D4 medium residues 1-70_106-117_181-203

PDB

Domain cluster: representative

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1gsaA03	3.30.1490.20	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain	0.58	34.0	4.12e-01	72.4%	93.8%
3orqA03	3.30.1490.20	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain	0.56	32.0	3.84e-01	71.4%	92.1%
1oaoC01	1.10.8.190	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Carbon monoxide dehydrogenase alpha subunit. Chain M, domain 1	0.55	42.0	4.04e-01	80.0%	81.7%
3h3gA03	4.10.1240.10	Few Secondary Structures › Irregular › Hormone receptor fold › GPCR, family 2, extracellular hormone receptor domain	0.55	35.0	3.58e-01	93.3%	66.0%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3339353	5041.1.1.0 ↗	extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C	0.57	36.0	3.92e-01	99.0%	75.6%
3693045	101.1.2.88 ↗	alpha arrays › HTH › HTH › winged helix domain › Dimerisation	0.50	30.0	2.63e-01	90.5%	38.7%

D5 medium residues 71-105_118-180_204-228

PDB

Domain cluster: representative

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5wm1A02	3.30.70.270	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain	0.51	38.0	4.05e-01	78.9%	96.3%
1irxA05	1.10.10.350	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.51	32.0	3.62e-01	86.2%	83.9%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3510640	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.50	31.0	3.50e-01	87.8%	82.2%

D6 medium residues 476-588

PDB

Domain cluster: rep: OM732337.1__UNA02175.1__vBAmaSR9Y3_42__00042__D369-494

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF08706.17 best	D5_N	27.1	6.50e-06	87.6%	39.5%

CATH (10)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2p5kA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.69	36.0	4.65e-01	96.5%	90.5%
3mwmA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	37.0	4.43e-01	99.1%	100.0%
2m7bA00	1.10.10.1920	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.57	38.0	4.40e-01	75.2%	98.7%
5k3hA01	1.10.540.10	Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain	0.54	37.0	3.64e-01	100.0%	64.5%
2yykA01	1.10.3140.10	Mainly Alpha › Orthogonal Bundle › 4-hydroxybutyryl-coa dehydratase, domain 1 › 4-hydroxybutyryl-coa dehydratase, domain 1	0.54	38.0	3.57e-01	70.8%	74.5%
1zp2A02	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.54	32.0	3.30e-01	71.7%	58.0%
1v4pC01	3.30.980.10	Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2	0.54	39.0	4.01e-01	74.3%	87.0%
2reoA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.53	39.0	3.26e-01	77.9%	63.8%
3bqkA02	1.20.1310.20	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain	0.52	38.0	3.50e-01	77.9%	83.9%
1r1dA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.50	40.0	3.21e-01	88.5%	66.1%

ECOD (11)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5003620	2004.1.1.409 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906	0.86	76.0	5.24e-01	99.1%	31.3%
5022019	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.83	57.0	6.73e-01	74.3%	100.0%
5082325	3705.1.1.3 ↗	alpha arrays › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Phage_holin_6_1	0.74	46.0	5.60e-01	72.6%	100.0%
4934293	4993.1.1.0 ↗	extended segments › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit	0.66	40.0	4.68e-01	76.1%	85.0%
4937420	2004.1.1.42 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE	0.63	53.0	3.42e-01	90.3%	53.1%
4956937	2484.1.1.59 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA	0.63	46.0	3.24e-01	77.9%	25.3%
3204938	101.1.1.228 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Eaf7	0.59	41.0	4.49e-01	70.8%	98.9%
3575378	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.59	42.0	4.55e-01	76.1%	88.4%
3995176	316.1.1.25 ↗	a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Nrap_D4	0.58	41.0	3.51e-01	72.6%	68.0%
3361	107.1.1.6 ↗	alpha arrays › Cytochrome c-like › Cytochrome c › Cytochrome c › Dehyd-heme_bind	0.54	35.0	4.00e-01	76.1%	89.3%
4640576	2006.1.1.44 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase, Hydrolase_like	0.52	47.0	3.75e-01	99.1%	85.3%

D7 medium residues 600-620_769-812

PDB

Domain cluster: representative

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3htvA02	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.56	46.0	3.42e-01	96.9%	35.1%
6o9aA01	3.40.190.10	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II	0.53	44.0	3.45e-01	95.4%	62.9%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5081314	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.86	80.0	5.15e-01	100.0%	79.2%
3594777	376.1.1.0 ↗	few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box	0.66	55.0	4.83e-01	90.8%	67.4%
3974057	2011.1.1.10 ↗	a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › FGase	0.55	47.0	3.17e-01	98.5%	98.9%

D8 medium residues 831-949

PDB

Domain cluster: representative

CATH (20)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2qbyA03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.71	44.0	4.98e-01	79.0%	82.2%
1ug8A00	3.30.1370.50	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain	0.69	39.0	4.46e-01	76.5%	74.7%
2qbyB03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.67	43.0	4.82e-01	79.8%	83.5%
6kf9G01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	35.0	4.06e-01	76.5%	75.6%
5dymA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.63	40.0	4.39e-01	79.0%	79.2%
4kt5C00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.62	38.0	4.24e-01	77.3%	79.5%
7dl8C01	3.30.110.20	Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain	0.62	35.0	3.94e-01	76.5%	73.0%
1bm9A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	38.0	3.84e-01	76.5%	60.8%
1repC02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	41.0	4.60e-01	76.5%	91.2%
3g3sA01	3.40.630.110	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › GNAT acetyltransferase-like	0.59	31.0	3.15e-01	76.5%	48.3%
7jgsG02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	43.0	4.74e-01	84.0%	96.9%
4p55B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.54	39.0	4.20e-01	73.9%	99.0%
2dqlA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.54	39.0	4.02e-01	83.2%	78.3%
3hluA00	3.30.70.120	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.54	32.0	3.89e-01	74.8%	94.5%
4mspB02	1.10.238.10	Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand	0.54	32.0	3.91e-01	74.8%	93.3%
1fpqA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.54	37.0	3.67e-01	79.8%	65.1%
5w2fA01	3.30.780.10	Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain	0.53	35.0	3.99e-01	81.5%	93.0%
4z9eA00	3.30.110.20	Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain	0.53	33.0	3.81e-01	76.5%	87.1%
1j4wA01	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.51	31.0	3.66e-01	70.6%	95.9%
4ozjA00	3.30.70.120	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.50	32.0	3.38e-01	75.6%	72.1%

ECOD (67)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5022021	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.89	62.0	6.31e-01	83.2%	73.0%
5029778	101.1.2.43 ↗	alpha arrays › HTH › HTH › winged helix domain › Pox_D5	0.81	55.0	6.28e-01	84.0%	92.2%
4109840	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.72	45.0	4.84e-01	76.5%	74.0%
4956520	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.68	46.0	4.77e-01	79.8%	73.6%
4961270	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.68	46.0	4.89e-01	79.8%	78.1%
4314672	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.68	43.0	4.62e-01	79.8%	72.4%
5005164	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.67	44.0	4.58e-01	79.0%	72.2%
3481547	101.1.2.68 ↗	alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34	0.67	47.0	4.42e-01	76.5%	58.0%
3788427	101.1.2.207 ↗	alpha arrays › HTH › HTH › winged helix domain › TFC3_eWH	0.67	41.0	4.44e-01	77.3%	73.0%
5065786	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.66	44.0	4.44e-01	79.8%	66.7%
4284507	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.66	46.0	4.85e-01	79.8%	81.0%
4325040	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.65	55.0	5.33e-01	89.1%	89.2%
4312327	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.64	48.0	4.43e-01	77.3%	63.5%
4990676	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.64	45.0	4.67e-01	79.8%	78.2%
5050129	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.64	45.0	4.72e-01	79.8%	79.1%
3306699	101.1.2.517 ↗	alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD	0.64	36.0	2.51e-01	77.3%	16.5%
4966558	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.64	35.0	4.05e-01	77.3%	74.1%
4943364	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.63	44.0	4.38e-01	79.8%	69.1%
4934172	242.1.1.7 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3	0.63	36.0	4.55e-01	76.5%	95.7%
4947062	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.63	40.0	4.37e-01	79.0%	78.9%
4487383	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.63	49.0	5.13e-01	85.7%	90.0%
5055466	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.62	46.0	4.67e-01	79.8%	78.3%
5011183	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.62	43.0	4.50e-01	79.8%	77.3%
4961841	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.62	52.0	5.06e-01	89.1%	88.5%
4982781	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.62	43.0	4.46e-01	79.8%	76.4%
4970516	2003.6.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like	0.62	38.0	3.66e-01	79.0%	52.9%
4173782	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.62	43.0	4.38e-01	79.8%	73.9%
4029392	375.1.1.179 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha	0.61	36.0	3.15e-01	76.5%	36.2%
2609	101.1.2.38 ↗	alpha arrays › HTH › HTH › winged helix domain › RTP	0.61	38.0	3.84e-01	76.5%	60.8%
3464534	101.1.2.641 ↗	alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1, DUF7647	0.61	45.0	2.87e-01	92.4%	16.4%
4979490	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.61	50.0	4.99e-01	88.2%	86.7%
4974161	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.61	50.0	4.96e-01	87.4%	88.7%
3695303	320.1.1.0 ↗	a+b two layers › R3H domain-like › R3H domain › R3H domain	0.61	40.0	3.92e-01	76.5%	61.7%
4948099	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.60	43.0	4.45e-01	79.8%	79.1%
4933997	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.60	49.0	4.98e-01	87.4%	86.7%
5003874	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.60	49.0	4.89e-01	85.7%	90.0%
5065308	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.59	42.0	4.24e-01	79.8%	72.5%
3840298	101.1.2.394 ↗	alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1	0.59	42.0	4.16e-01	95.0%	69.2%
4966192	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.58	46.0	4.76e-01	84.0%	89.6%
4503351	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.58	42.0	4.50e-01	83.2%	85.7%
3797519	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.58	45.0	2.91e-01	91.6%	17.3%
5077356	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.58	47.0	4.61e-01	85.7%	80.8%
4203701	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.58	45.0	4.44e-01	83.2%	76.0%
5029327	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.58	44.0	4.43e-01	79.8%	79.2%
3602264	242.1.1.7 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3	0.58	38.0	4.37e-01	87.4%	92.9%
3602910	242.1.1.7 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3	0.57	37.0	4.20e-01	82.4%	87.8%
4672256	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.56	44.0	4.48e-01	83.2%	83.5%
3181301	101.1.2.569 ↗	alpha arrays › HTH › HTH › winged helix domain › PF28722	0.56	45.0	4.23e-01	85.7%	75.9%
4992480	242.1.1.0 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases	0.55	37.0	4.21e-01	89.1%	91.1%
4971711	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.55	44.0	4.34e-01	84.9%	80.8%
5022418	304.5.1.7 ↗	a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179	0.55	31.0	4.04e-01	70.6%	100.0%
3479163	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.55	43.0	4.24e-01	83.2%	80.8%
4938000	242.1.1.7 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3	0.54	37.0	4.05e-01	79.8%	87.4%
3549847	101.1.2.394 ↗	alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1	0.54	44.0	3.15e-01	89.9%	64.3%
4971999	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.54	43.0	4.27e-01	86.6%	83.2%
4061942	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.53	46.0	4.55e-01	93.3%	88.0%
5030783	242.1.1.3 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › Hom_end	0.53	37.0	4.06e-01	80.7%	88.4%
3933222	101.1.2.111 ↗	alpha arrays › HTH › HTH › winged helix domain › RQC	0.53	38.0	3.55e-01	76.5%	58.1%
3625937	101.1.2.216 ↗	alpha arrays › HTH › HTH › winged helix domain › CED4_WHD	0.53	44.0	4.11e-01	90.8%	88.7%
3590219	304.5.1.7 ↗	a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179	0.53	32.0	3.58e-01	75.6%	78.9%
4977841	310.3.1.0 ↗	a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related	0.52	32.0	3.75e-01	74.8%	91.3%
3413597	101.1.2.394 ↗	alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1	0.52	44.0	3.15e-01	91.6%	58.6%
4638999	304.5.1.7 ↗	a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179	0.52	31.0	3.65e-01	75.6%	87.5%
3642333	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.51	38.0	3.29e-01	76.5%	51.4%
3957049	330.10.1.1 ↗	a+b two layers › dsRBD-like › Heterocyclase TruD C-terminal domain › Heterocyclase TruD C-terminal domain › YcaO	0.51	38.0	3.48e-01	78.2%	84.8%
3587356	304.5.1.7 ↗	a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179	0.51	31.0	3.47e-01	79.8%	78.9%
3935690	101.1.2.111 ↗	alpha arrays › HTH › HTH › winged helix domain › RQC	0.50	37.0	3.64e-01	77.3%	70.8%