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IMGVR_UViG_3300005275_000006-3300005275-Ga0065719_10659081
Arc-VirIMGVR_UViG_3300005275_000006-3300005275-Ga0065719_10659081
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-47_176-193
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ibwA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.67 | 34.0 | 3.18e-01 | 78.5% | 38.0% |
| 7vc6A02 | 3.40.50.1700 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain | 0.56 | 42.0 | 3.07e-01 | 84.6% | 92.3% |
| 4rs6A01 | 3.30.1120.30 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › POLO box domain | 0.55 | 44.0 | 3.66e-01 | 87.7% | 100.0% |
| 3g2eB00 | 3.40.920.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.55 | 33.0 | 2.36e-01 | 78.5% | 20.5% |
| 1ykdB02 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.55 | 40.0 | 2.93e-01 | 78.5% | 89.8% |
| 3rjlA02 | 3.40.309.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 | 0.55 | 40.0 | 2.94e-01 | 78.5% | 69.6% |
| 1zhvA00 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.54 | 40.0 | 3.28e-01 | 83.1% | 89.6% |
| 1mo7A00 | 3.40.1110.10 | Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N | 0.52 | 43.0 | 3.10e-01 | 98.5% | 51.6% |
| 2zdiC00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 42.0 | 3.24e-01 | 90.8% | 44.6% |
| 3zqmA00 | 6.10.140.2160 | Special › Helix non-globular › Helix Hairpins › | 0.50 | 37.0 | 3.82e-01 | 89.2% | 88.1% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5054060 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.69 | 36.0 | 3.34e-01 | 76.9% | 37.6% |
| 3175626 | 331.1.1.13 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › CPSF73-100_C | 0.67 | 31.0 | 2.98e-01 | 70.8% | 37.3% |
| 3172782 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.64 | 36.0 | 3.27e-01 | 78.5% | 41.2% |
| 4635441 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.62 | 33.0 | 2.96e-01 | 78.5% | 34.7% |
| 5029252 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.57 | 48.0 | 4.03e-01 | 100.0% | 80.8% |
| 3375836 | 376.1.1.21 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 | 0.56 | 39.0 | 3.43e-01 | 72.3% | 62.0% |
| 3376271 | 64.1.1.8 ↗ | beta meanders › WW domain-like › WW domain › WW domain › DUF7028 | 0.55 | 36.0 | 3.36e-01 | 96.9% | 51.8% |
| 3708460 | 3003.1.1.1 ↗ | a+b complex topology › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › N-terminal subdomain in DNA replication initiator (cdc21/cdc54) › MCM_N | 0.53 | 40.0 | 3.19e-01 | 80.0% | 80.8% |
| 3519677 | 101.1.2.4 ↗ | alpha arrays › HTH › HTH › winged helix domain › Forkhead | 0.52 | 43.0 | 3.38e-01 | 92.3% | 76.4% |
| 4971395 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.52 | 42.0 | 3.72e-01 | 89.2% | 98.9% |
| 3952661 | 241.1.1.6 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › YbjN | 0.51 | 40.0 | 3.01e-01 | 89.2% | 38.8% |
| 2141735 | 219.1.1.69 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › GtgE | 0.50 | 42.0 | 3.11e-01 | 100.0% | 83.1% |
| 3689905 | 859.1.1.4 ↗ | a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › ATG13 | 0.50 | 40.0 | 2.85e-01 | 89.2% | 56.2% |
D2
medium
residues 48-175
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00303.25 best | Thymidylat_synt | 29.6 | 5.30e-07 | 81.2% | 34.3% |
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1bo7A00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.84 | 80.0 | 5.80e-01 | 100.0% | 70.6% |
| 1tisA00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.84 | 80.0 | 5.96e-01 | 100.0% | 64.0% |
| 1bkpA00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.83 | 79.0 | 5.93e-01 | 100.0% | 62.6% |
| 3v8hC00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.82 | 79.0 | 5.85e-01 | 100.0% | 74.7% |
| 1b5eA00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.82 | 78.0 | 6.14e-01 | 100.0% | 72.6% |
| 3egyX00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.81 | 77.0 | 6.14e-01 | 100.0% | 61.1% |
| 2rrlA01 | 3.30.750.140 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.72 | 50.0 | 5.22e-01 | 82.0% | 77.4% |
| 6upsA01 | 3.40.395.10 | Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A | 0.66 | 44.0 | 4.15e-01 | 77.3% | 56.1% |
| 1euvA02 | 3.30.310.130 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Ubiquitin-related | 0.65 | 46.0 | 5.00e-01 | 71.9% | 94.3% |
| 3fg6A01 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.64 | 36.0 | 4.07e-01 | 78.1% | 70.7% |
| 1vw5A00 | 3.30.70.1420 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Structure from the mobile metagenome of cole harbour salt marsh: integron cassette protein hfx_cass1 | 0.64 | 45.0 | 4.23e-01 | 71.9% | 75.5% |
| 1i74A02 | 3.10.310.20 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain | 0.62 | 33.0 | 3.43e-01 | 77.3% | 53.8% |
| 2l72A00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.59 | 46.0 | 4.75e-01 | 81.2% | 92.4% |
| 4lizA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.57 | 43.0 | 4.21e-01 | 78.1% | 85.5% |
| 3mogA03 | 3.30.750.190 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.57 | 40.0 | 4.54e-01 | 94.5% | 97.9% |
| 2mv2A00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.57 | 43.0 | 4.17e-01 | 81.2% | 87.2% |
| 1cfyA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.56 | 41.0 | 4.09e-01 | 77.3% | 88.0% |
| 1s3zA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.55 | 43.0 | 4.13e-01 | 82.8% | 85.0% |
| 2hqyA02 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.54 | 48.0 | 4.41e-01 | 97.7% | 91.7% |
| 1uwvA03 | 2.40.50.1070 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.53 | 38.0 | 3.71e-01 | 74.2% | 67.2% |
| 3bt7A02 | 2.40.50.1070 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.53 | 38.0 | 3.66e-01 | 73.4% | 69.7% |
| 1vkcA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.53 | 41.0 | 4.03e-01 | 82.0% | 92.8% |
| 2wpwC00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.53 | 47.0 | 3.57e-01 | 100.0% | 46.8% |
| 2euiA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.53 | 39.0 | 3.84e-01 | 77.3% | 89.3% |
| 4e2aA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.52 | 40.0 | 3.66e-01 | 80.5% | 76.5% |
| 3tt2A00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.52 | 46.0 | 3.51e-01 | 97.7% | 41.9% |
| 4at7B02 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.52 | 41.0 | 3.60e-01 | 83.6% | 80.6% |
| 1m4jA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.52 | 39.0 | 3.88e-01 | 79.7% | 88.7% |
| 3g7kB02 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.52 | 39.0 | 3.51e-01 | 78.9% | 92.3% |
| 1ufhA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.51 | 40.0 | 3.74e-01 | 81.2% | 87.1% |
| 2lxxA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.51 | 43.0 | 4.09e-01 | 91.4% | 86.8% |
| 1sqhA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.51 | 38.0 | 3.54e-01 | 78.9% | 75.3% |
| 7tocA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 45.0 | 3.83e-01 | 97.7% | 90.9% |
| 2ob0C01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.51 | 39.0 | 3.65e-01 | 82.0% | 72.2% |
| 4xq7A01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.50 | 38.0 | 3.58e-01 | 80.5% | 85.3% |
ECOD (59)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5050802 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.88 | 85.0 | 6.30e-01 | 100.0% | 76.0% |
| 4582423 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.87 | 83.0 | 6.77e-01 | 100.0% | 74.8% |
| 4954631 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.87 | 83.0 | 6.62e-01 | 100.0% | 77.0% |
| 4985883 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.87 | 83.0 | 6.82e-01 | 100.0% | 70.0% |
| 5015648 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.87 | 83.0 | 6.88e-01 | 100.0% | 75.1% |
| 4976145 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.86 | 83.0 | 6.64e-01 | 100.0% | 73.8% |
| 4937005 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.86 | 82.0 | 5.82e-01 | 100.0% | 60.9% |
| 4949404 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.86 | 82.0 | 6.54e-01 | 100.0% | 69.1% |
| 4932636 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.86 | 82.0 | 6.68e-01 | 100.0% | 73.0% |
| 4938917 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.86 | 82.0 | 6.39e-01 | 100.0% | 66.1% |
| 5031349 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.85 | 82.0 | 6.67e-01 | 100.0% | 74.0% |
| 5046158 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.85 | 82.0 | 6.85e-01 | 100.0% | 75.5% |
| 5022688 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.85 | 81.0 | 6.84e-01 | 100.0% | 75.9% |
| 5059575 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.85 | 82.0 | 6.03e-01 | 100.0% | 62.4% |
| 4108234 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.85 | 82.0 | 5.86e-01 | 100.0% | 70.9% |
| 4664958 | 266.1.1.0 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase | 0.85 | 81.0 | 6.18e-01 | 100.0% | 65.5% |
| 2028021 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.85 | 81.0 | 5.86e-01 | 100.0% | 54.7% |
| 5005700 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.85 | 77.0 | 6.82e-01 | 100.0% | 69.7% |
| 4151800 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.84 | 81.0 | 5.90e-01 | 100.0% | 69.7% |
| 3944795 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.84 | 81.0 | 5.64e-01 | 100.0% | 73.0% |
| 3479792 | 266.1.1.0 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase | 0.84 | 81.0 | 5.84e-01 | 100.0% | 62.6% |
| 3203076 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.84 | 80.0 | 5.74e-01 | 100.0% | 69.9% |
| 4228846 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.84 | 80.0 | 5.77e-01 | 100.0% | 68.4% |
| 4225236 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.84 | 80.0 | 5.98e-01 | 100.0% | 64.3% |
| 2540892 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.84 | 80.0 | 5.71e-01 | 100.0% | 59.0% |
| 3824671 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.83 | 79.0 | 5.96e-01 | 100.0% | 65.4% |
| 1900468 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.83 | 79.0 | 5.97e-01 | 100.0% | 62.4% |
| 4086625 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.83 | 79.0 | 5.89e-01 | 100.0% | 63.5% |
| 4599962 | 266.1.1.0 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase | 0.83 | 79.0 | 5.92e-01 | 100.0% | 62.4% |
| 4974926 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.82 | 78.0 | 6.41e-01 | 100.0% | 71.6% |
| 1900473 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.82 | 78.0 | 6.09e-01 | 100.0% | 71.1% |
| 3164619 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.81 | 76.0 | 5.75e-01 | 100.0% | 65.7% |
| 5001950 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.80 | 75.0 | 5.87e-01 | 100.0% | 65.5% |
| 3839723 | 327.6.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › FeS_assembly_P | 0.68 | 36.0 | 4.42e-01 | 77.3% | 81.2% |
| 3964844 | 327.6.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like | 0.67 | 35.0 | 4.12e-01 | 78.9% | 71.1% |
| 3717573 | 2003.1.5.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr | 0.64 | 46.0 | 3.16e-01 | 74.2% | 30.2% |
| 1422950 | 324.1.2.0 ↗ | a+b two layers › OsmC-like › OsmC-like | 0.64 | 45.0 | 4.22e-01 | 71.9% | 74.5% |
| 3605866 | 2003.1.5.156 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_31 | 0.63 | 46.0 | 3.18e-01 | 74.2% | 31.6% |
| 5020891 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.60 | 44.0 | 4.96e-01 | 100.0% | 97.0% |
| 3781911 | 213.1.1.61 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › GNAT_LYC1-like | 0.58 | 53.0 | 4.44e-01 | 100.0% | 89.8% |
| 3656918 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.58 | 44.0 | 3.54e-01 | 79.7% | 66.3% |
| 5046305 | 213.1.1.0 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) | 0.58 | 51.0 | 4.85e-01 | 100.0% | 82.0% |
| 5020062 | 304.36.1.0 ↗ | a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like | 0.57 | 43.0 | 4.56e-01 | 100.0% | 87.8% |
| 4236550 | 2003.1.5.82 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 | 0.57 | 41.0 | 2.86e-01 | 75.0% | 26.9% |
| 1130223 | 2003.1.1.77 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3HCDH_RFF | 0.57 | 40.0 | 4.43e-01 | 95.3% | 93.0% |
| 3820137 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.56 | 44.0 | 3.70e-01 | 82.8% | 81.5% |
| 4013260 | 327.5.1.5 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C_3 | 0.55 | 39.0 | 2.90e-01 | 73.4% | 64.1% |
| 5046874 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.55 | 49.0 | 4.32e-01 | 99.2% | 83.2% |
| 3883654 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.54 | 42.0 | 3.76e-01 | 83.6% | 76.6% |
| 3959758 | 213.1.1.0 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) | 0.53 | 47.0 | 4.11e-01 | 98.4% | 92.5% |
| 5074675 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.53 | 48.0 | 4.43e-01 | 99.2% | 83.0% |
| 5082956 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.53 | 38.0 | 3.66e-01 | 75.0% | 86.7% |
| 3357649 | 213.1.1.5 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › MOZ_SAS | 0.53 | 41.0 | 3.81e-01 | 82.8% | 86.1% |
| 5049874 | 213.1.1.0 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) | 0.52 | 45.0 | 3.97e-01 | 97.7% | 81.5% |
| 4078398 | 2003.1.5.174 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr, Methyltransf_15 | 0.52 | 37.0 | 2.66e-01 | 75.0% | 25.7% |
| 4271018 | 2003.1.5.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr | 0.51 | 36.0 | 2.58e-01 | 74.2% | 24.9% |
| 3726398 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.51 | 43.0 | 3.78e-01 | 93.0% | 69.2% |
| 4947690 | 327.5.1.4 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C | 0.50 | 35.0 | 3.40e-01 | 70.3% | 66.4% |
| 4339805 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.50 | 37.0 | 3.21e-01 | 76.6% | 72.7% |