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IMGVR_UViG_3300005521_000790-3300005521-Ga0066862_100070042
Arc-VirIMGVR_UViG_3300005521_000790-3300005521-Ga0066862_100070042
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 27-81
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ilkA02 | 1.10.8.590 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.70 | 50.0 | 4.63e-01 | 76.4% | 60.3% |
| 3tw6A06 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.70 | 49.0 | 4.98e-01 | 100.0% | 75.9% |
| 4rflA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.69 | 52.0 | 3.59e-01 | 85.5% | 57.3% |
| 4c0kA01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.66 | 49.0 | 4.05e-01 | 80.0% | 82.2% |
| 2hdoA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.65 | 39.0 | 3.75e-01 | 70.9% | 51.6% |
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.65 | 51.0 | 4.89e-01 | 90.9% | 82.1% |
| 6aqgD02 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.64 | 44.0 | 2.74e-01 | 72.7% | 95.3% |
| 1j8yF01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.64 | 56.0 | 4.85e-01 | 100.0% | 74.4% |
| 1x42A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.63 | 51.0 | 4.64e-01 | 98.2% | 78.3% |
| 7ml0M01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.63 | 52.0 | 4.69e-01 | 98.2% | 67.1% |
| 2daxA01 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.63 | 53.0 | 3.91e-01 | 98.2% | 36.2% |
| 1r6bX03 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.63 | 53.0 | 4.62e-01 | 100.0% | 64.8% |
| 1iv8A04 | 1.10.10.470 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Maltooligosyl trehalose synthase; domain 4 | 0.62 | 51.0 | 4.19e-01 | 98.2% | 50.5% |
| 1t9kA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.62 | 52.0 | 3.88e-01 | 94.5% | 70.7% |
| 2icwG02 | 1.10.10.530 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › mam-mhc complex, Chain D, Domain 2 | 0.62 | 44.0 | 3.71e-01 | 80.0% | 46.1% |
| 1vt0k00 | 1.10.3230.20 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › P22 tail accessory factor (Gp4) | 0.62 | 49.0 | 3.73e-01 | 92.7% | 57.2% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.62 | 54.0 | 4.65e-01 | 100.0% | 78.4% |
| 3ooqA02 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.62 | 41.0 | 2.66e-01 | 70.9% | 43.0% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.61 | 51.0 | 4.23e-01 | 96.4% | 77.8% |
| 2ffjA01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.60 | 47.0 | 4.70e-01 | 90.9% | 87.5% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.60 | 50.0 | 4.07e-01 | 98.2% | 86.3% |
| 3h87B00 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.60 | 46.0 | 3.59e-01 | 87.3% | 54.3% |
| 3vkhB07 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 52.0 | 3.62e-01 | 100.0% | 96.3% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 46.0 | 3.92e-01 | 87.3% | 53.1% |
| 3cl3A02 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.59 | 40.0 | 3.52e-01 | 72.7% | 67.0% |
| 4hteA01 | 1.20.58.1730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 41.0 | 3.04e-01 | 72.7% | 35.7% |
| 1chuA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.58 | 41.0 | 3.55e-01 | 74.5% | 51.1% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.58 | 40.0 | 3.48e-01 | 72.7% | 63.6% |
| 1iqpA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.57 | 46.0 | 3.99e-01 | 96.4% | 56.4% |
| 4qiwK00 | 3.90.940.10 | Alpha Beta › Alpha-Beta Complex › Eukaryotic RPB6 RNA polymerase subunit › RNA polymerase subunit, RPB6/omega | 0.57 | 41.0 | 4.11e-01 | 78.2% | 100.0% |
| 4azcA02 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.57 | 43.0 | 4.25e-01 | 83.6% | 78.0% |
| 1lj2A00 | 1.20.5.970 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Nonstructural RNA-binding protein | 0.56 | 46.0 | 3.82e-01 | 100.0% | 49.1% |
| 2kiwA01 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.56 | 38.0 | 3.44e-01 | 74.5% | 51.2% |
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.56 | 41.0 | 3.68e-01 | 85.5% | 55.2% |
| 1r4gA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.54 | 41.0 | 4.17e-01 | 98.2% | 92.5% |
| 4i2aA02 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.54 | 39.0 | 3.83e-01 | 98.2% | 72.9% |
| 4qpkB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.54 | 46.0 | 3.56e-01 | 100.0% | 94.8% |
| 7zhgO01 | 1.10.8.50 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.54 | 45.0 | 4.28e-01 | 100.0% | 80.3% |
| 6wjaA02 | 3.90.25.10 | Alpha Beta › Alpha-Beta Complex › UDP-galactose 4-epimerase; domain 1 › UDP-galactose 4-epimerase, domain 1 | 0.52 | 43.0 | 3.53e-01 | 94.5% | 67.3% |
| 7rzy101 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 39.0 | 2.69e-01 | 83.6% | 85.0% |
| 4nphA02 | 1.20.1270.330 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.50 | 37.0 | 3.44e-01 | 81.8% | 87.8% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5071624 | 2002.1.1.25 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HMGL-like | 0.73 | 58.0 | 3.44e-01 | 87.3% | 12.5% |
| 4948317 | 103.5.1.0 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like | 0.72 | 58.0 | 6.06e-01 | 92.7% | 100.0% |
| 4038157 | 103.5.1.0 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like | 0.71 | 55.0 | 5.78e-01 | 89.1% | 96.0% |
| 4026195 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.70 | 48.0 | 4.40e-01 | 72.7% | 53.3% |
| 4973086 | 103.5.1.0 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like | 0.70 | 57.0 | 5.75e-01 | 92.7% | 90.9% |
| 4367678 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.69 | 59.0 | 5.62e-01 | 96.4% | 90.8% |
| 5030767 | 103.5.1.0 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like | 0.69 | 57.0 | 5.57e-01 | 92.7% | 88.3% |
| 3229657 | 148.1.3.27 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_10 | 0.68 | 59.0 | 5.28e-01 | 100.0% | 93.8% |
| 4984693 | 103.5.1.0 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like | 0.68 | 54.0 | 5.59e-01 | 89.1% | 98.0% |
| 4299866 | 103.5.1.4 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like › HCS_D2 | 0.67 | 51.0 | 5.07e-01 | 96.4% | 80.0% |
| 3436690 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.65 | 56.0 | 4.83e-01 | 100.0% | 66.7% |
| 3998578 | 142.1.1.41 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › RabGAP-TBC | 0.65 | 55.0 | 5.28e-01 | 100.0% | 96.9% |
| 4943201 | 181.1.1.32 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54 | 0.65 | 57.0 | 4.94e-01 | 98.2% | 69.4% |
| 3988991 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.65 | 57.0 | 4.87e-01 | 100.0% | 66.7% |
| 3603904 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.65 | 57.0 | 4.85e-01 | 100.0% | 66.7% |
| 4953164 | 103.5.1.0 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like | 0.64 | 49.0 | 4.94e-01 | 87.3% | 85.5% |
| 3373467 | 327.11.2.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_6 | 0.64 | 53.0 | 4.37e-01 | 96.4% | 50.5% |
| 3223572 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.64 | 52.0 | 4.96e-01 | 94.5% | 87.7% |
| 3841126 | 5038.2.1.0 ↗ | alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like | 0.64 | 53.0 | 3.77e-01 | 98.2% | 54.1% |
| None | — | 0.63 | 47.0 | 2.84e-01 | 85.5% | 11.8% | |
| 5023530 | 4957.1.1.0 ↗ | a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit | 0.63 | 54.0 | 5.29e-01 | 100.0% | 95.0% |
| 4942992 | 103.5.1.0 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like | 0.63 | 50.0 | 5.16e-01 | 94.5% | 100.0% |
| 3934535 | 103.11.1.0 ↗ | alpha arrays › RuvA-C › RMI1 N-terminal helical domain-related › RMI1 N-terminal helical domain-related | 0.62 | 51.0 | 5.06e-01 | 100.0% | 93.3% |
| 4189656 | 142.1.1.33 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › DUF2603 | 0.62 | 52.0 | 4.81e-01 | 100.0% | 73.3% |
| 4167763 | 2002.1.1.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels | 0.62 | 48.0 | 2.89e-01 | 89.1% | 12.2% |
| 4024018 | 327.11.2.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_6 | 0.62 | 51.0 | 3.94e-01 | 94.5% | 41.5% |
| 4120356 | 103.5.1.4 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like › HCS_D2 | 0.62 | 50.0 | 4.23e-01 | 98.2% | 52.0% |
| 4032129 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.62 | 53.0 | 5.04e-01 | 96.4% | 86.2% |
| 4946843 | 4009.1.1.1 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom | 0.62 | 49.0 | 4.69e-01 | 90.9% | 83.1% |
| 5021020 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.62 | 44.0 | 3.78e-01 | 80.0% | 46.7% |
| 3951354 | 103.5.1.0 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like | 0.61 | 49.0 | 4.74e-01 | 92.7% | 84.6% |
| 4645504 | 103.5.1.3 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like › IPMS_D2 | 0.61 | 48.0 | 4.13e-01 | 92.7% | 55.8% |
| 5053994 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.60 | 51.0 | 4.63e-01 | 96.4% | 78.7% |
| 4939237 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.60 | 47.0 | 4.55e-01 | 90.9% | 81.5% |
| 5059346 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.60 | 50.0 | 4.46e-01 | 100.0% | 70.6% |
| 4004431 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.60 | 49.0 | 2.98e-01 | 98.2% | 83.0% |
| 3393434 | 108.1.1.123 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_EFHB_C | 0.60 | 48.0 | 4.27e-01 | 100.0% | 60.0% |
| 3899930 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.59 | 43.0 | 2.95e-01 | 78.2% | 38.0% |
| 5070580 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.59 | 47.0 | 4.68e-01 | 96.4% | 89.8% |
| 4945368 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.58 | 46.0 | 4.17e-01 | 92.7% | 65.0% |
| 3226578 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.58 | 49.0 | 4.11e-01 | 100.0% | 53.3% |
| 4203116 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.58 | 47.0 | 4.56e-01 | 100.0% | 100.0% |
| 3831850 | 2002.1.1.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels | 0.57 | 48.0 | 2.86e-01 | 100.0% | 11.2% |
| 4115978 | 103.1.1.6 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C | 0.56 | 46.0 | 4.43e-01 | 96.4% | 83.1% |
| 3244254 | 101.1.8.23 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › DUF4473 | 0.56 | 48.0 | 4.31e-01 | 98.2% | 73.8% |
| 4997208 | 2004.1.1.146 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase | 0.56 | 47.0 | 2.99e-01 | 98.2% | 20.0% |
| 2875232 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.56 | 47.0 | 4.04e-01 | 100.0% | 56.7% |
| 3210910 | 102.1.1.62 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › DUF4473 | 0.54 | 44.0 | 4.01e-01 | 98.2% | 72.5% |
| 4934221 | 148.1.3.20 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_2 | 0.54 | 39.0 | 3.71e-01 | 80.0% | 77.1% |
| 5080189 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 41.0 | 3.35e-01 | 85.5% | 51.8% |