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IMGVR_UViG_3300005607_000421-3300005607-Ga0070740_100006102

Arc-Vir

IMGVR_UViG_3300005607_000421-3300005607-Ga0070740_100006102

Quality

83.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 368-450
PDB
Domain cluster: representative
CATH (59)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.72 59.0 5.60e-01 88.0% 80.4%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.70 55.0 4.63e-01 83.1% 75.9%
3l8kA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.68 49.0 3.59e-01 78.3% 28.6%
3kflA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.68 49.0 3.89e-01 77.1% 88.0%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 47.0 4.22e-01 100.0% 53.6%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.67 48.0 4.66e-01 75.9% 68.1%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 48.0 3.92e-01 77.1% 83.1%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 50.0 4.33e-01 80.7% 75.8%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.65 52.0 5.34e-01 89.2% 98.7%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.64 50.0 3.91e-01 83.1% 81.5%
3nxcA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 53.0 4.25e-01 97.6% 51.4%
3ppbA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 52.0 4.03e-01 91.6% 49.5%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 48.0 4.10e-01 81.9% 85.1%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.62 46.0 3.99e-01 78.3% 73.8%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 46.0 4.03e-01 79.5% 85.5%
3ziuA01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 44.0 3.15e-01 74.7% 36.2%
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.61 41.0 3.67e-01 100.0% 49.1%
6lpfA01 1.10.730.20 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › 0.61 48.0 3.91e-01 86.7% 63.2%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 45.0 4.22e-01 79.5% 82.5%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.60 43.0 3.87e-01 75.9% 63.0%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.60 48.0 4.30e-01 86.7% 81.5%
2cwoA01 1.20.58.1200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RNA silencing suppressor P21, N-terminal domain 0.59 43.0 4.56e-01 75.9% 85.1%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 42.0 4.43e-01 74.7% 83.8%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.59 45.0 4.52e-01 86.7% 80.0%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 44.0 3.93e-01 77.1% 65.5%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 46.0 4.27e-01 84.3% 84.9%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 44.0 4.15e-01 79.5% 83.3%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.58 44.0 4.39e-01 79.5% 88.5%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.58 51.0 3.77e-01 98.8% 74.8%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.58 43.0 4.05e-01 78.3% 80.4%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 42.0 4.05e-01 77.1% 88.3%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.57 43.0 3.76e-01 85.5% 52.7%
2gbbB00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.57 48.0 3.95e-01 100.0% 51.0%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.57 42.0 4.49e-01 88.0% 89.2%
7kypB01 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.56 50.0 3.49e-01 100.0% 74.4%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 3.91e-01 79.5% 85.2%
3zc0D00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 46.0 3.54e-01 89.2% 84.0%
1m4rB00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 43.0 3.67e-01 83.1% 85.1%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 45.0 4.01e-01 88.0% 69.4%
6ofsA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.56 46.0 3.44e-01 91.6% 71.2%
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 48.0 3.80e-01 100.0% 85.6%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 42.0 3.84e-01 80.7% 81.8%
3kmiA00 1.20.120.940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain 0.55 47.0 3.77e-01 95.2% 73.3%
1yy7A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 38.0 3.56e-01 72.3% 66.7%
4mk3A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 38.0 3.43e-01 71.1% 68.7%
2fp1B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.55 46.0 3.78e-01 100.0% 48.8%
4hteA01 1.20.58.1730 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 41.0 3.43e-01 91.6% 46.2%
4hd1A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.54 47.0 3.39e-01 100.0% 59.7%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 38.0 3.84e-01 74.7% 88.4%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 39.0 3.44e-01 75.9% 53.2%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 45.0 3.47e-01 100.0% 69.7%
4q5rA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 39.0 3.63e-01 79.5% 72.3%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.53 38.0 3.68e-01 74.7% 81.7%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 45.0 3.98e-01 95.2% 84.3%
1uddA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.51 43.0 3.27e-01 95.2% 69.3%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 45.0 4.13e-01 96.4% 86.1%
3vurA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 37.0 3.43e-01 78.3% 71.7%
4fp4A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 42.0 3.05e-01 90.4% 34.2%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.50 42.0 3.56e-01 91.6% 59.1%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5061943 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.75 67.0 5.80e-01 97.6% 83.2%
4552859 621.1.1.3 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.74 63.0 4.61e-01 94.0% 39.6%
5023246 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.73 63.0 5.00e-01 96.4% 54.9%
3989674 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.72 54.0 4.73e-01 78.3% 72.5%
3923698 627.1.1.0 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain 0.71 57.0 5.40e-01 86.7% 84.0%
4554825 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.71 60.0 5.84e-01 96.4% 84.4%
3710353 148.1.3.12 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_8 0.71 50.0 4.61e-01 74.7% 58.2%
3402481 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 48.0 4.14e-01 72.3% 72.3%
3386308 604.3.1.46 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › PF28048 0.69 56.0 5.48e-01 88.0% 80.0%
5011860 7516.1.1.26 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_tranf_2_3 0.69 63.0 4.03e-01 100.0% 53.5%
3837728 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.69 50.0 4.18e-01 74.7% 77.8%
3462175 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 53.0 4.53e-01 84.3% 66.9%
4403090 191.1.1.50 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › SlmA-like_C 0.66 56.0 4.75e-01 96.4% 66.9%
3742136 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.66 46.0 4.83e-01 72.3% 86.7%
3360875 7015.1.1.4 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › PLAC8 0.66 48.0 4.34e-01 77.1% 82.6%
4999868 604.1.1.264 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Oxidored_q2 0.66 49.0 4.76e-01 78.3% 80.0%
3257684 109.4.1.1341 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG3_N, COG3_C 0.66 51.0 3.67e-01 84.3% 29.6%
3219291 188.1.1.0 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain 0.65 57.0 4.16e-01 100.0% 36.1%
4954587 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.64 46.0 3.68e-01 74.7% 51.5%
3301847 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.64 46.0 4.34e-01 75.9% 79.0%
3266118 603.1.1.100 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.63 46.0 3.98e-01 75.9% 67.2%
3212811 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 49.0 4.25e-01 84.3% 90.8%
3670053 603.1.1.107 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Mlo 0.62 46.0 4.47e-01 77.1% 85.6%
3180119 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.62 44.0 4.40e-01 73.5% 89.4%
3815026 604.1.1.148 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N 0.62 47.0 4.74e-01 80.7% 89.4%
3462043 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.61 45.0 4.45e-01 79.5% 82.2%
3224585 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.61 47.0 4.22e-01 79.5% 77.3%
3586162 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.61 51.0 4.43e-01 90.4% 90.4%
4511937 603.1.1.139 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE_C, PF27021 0.61 47.0 3.82e-01 80.7% 56.0%
3619641 604.1.1.154 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27021 0.61 46.0 4.26e-01 79.5% 77.1%
3669330 604.1.1.148 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N 0.61 44.0 4.38e-01 75.9% 83.5%
4985507 604.10.1.0 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.60 48.0 4.68e-01 84.3% 85.6%
3731006 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.60 46.0 4.39e-01 79.5% 88.4%
3930556 140.1.1.5 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.60 48.0 4.36e-01 88.0% 96.5%
4342803 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 43.0 3.90e-01 74.7% 71.8%
4527444 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.59 51.0 3.39e-01 95.2% 43.3%
4154382 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.59 45.0 3.61e-01 83.1% 59.5%
2323994 604.37.1.0 alpha bundles › Spectrin repeat-like › Legionella effector Lem22 › Legionella effector Lem22 0.59 44.0 4.33e-01 79.5% 82.2%
3740894 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 45.0 4.46e-01 83.1% 90.0%
3701020 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.58 43.0 4.41e-01 77.1% 88.7%
4058767 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.58 41.0 3.54e-01 74.7% 61.4%
3470992 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.58 40.0 3.87e-01 73.5% 68.0%
3948903 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 48.0 3.80e-01 97.6% 76.5%
3390666 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 44.0 3.79e-01 80.7% 59.2%
3927740 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.58 47.0 3.65e-01 91.6% 75.4%
5059236 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.57 52.0 5.10e-01 100.0% 98.9%
3472767 5059.1.1.17 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TMEM234 0.57 45.0 4.41e-01 91.6% 78.9%
3750030 604.12.1.15 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Mito_morph_reg 0.57 41.0 4.00e-01 74.7% 81.1%
3227034 5069.1.3.65 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › PF31020 0.57 47.0 4.18e-01 91.6% 64.3%
3929509 5050.1.1.11 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 0.57 49.0 3.68e-01 100.0% 70.2%
3693297 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 41.0 4.44e-01 75.9% 98.6%
3838225 129.1.1.21 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › Competence 0.56 47.0 3.26e-01 94.0% 64.7%
4534540 3718.1.1.1 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT 0.56 42.0 3.84e-01 78.3% 69.5%
3497466 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.56 43.0 4.23e-01 83.1% 86.7%
4996103 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 48.0 3.81e-01 100.0% 82.2%
3883762 3718.1.1.5 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › Meis_PKNOX_N 0.56 43.0 3.84e-01 84.3% 65.0%
3580283 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 41.0 4.11e-01 78.3% 90.6%
2774319 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 48.0 3.55e-01 100.0% 71.7%
3497645 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.55 40.0 4.15e-01 77.1% 82.5%
5081636 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 46.0 3.54e-01 94.0% 77.8%
4984545 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.55 40.0 3.90e-01 77.1% 85.6%
3180530 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.54 41.0 3.82e-01 83.1% 98.2%
3390261 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.54 40.0 3.97e-01 79.5% 82.2%
3988277 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.54 44.0 3.15e-01 95.2% 77.3%
3968 150.1.2.5 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › TENA_THI-4 0.51 43.0 3.27e-01 95.2% 69.3%
2325490 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 45.0 4.08e-01 96.4% 83.0%
D2 medium residues 1-108_348-367
PDB
Domain cluster: representative
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.80 55.0 5.28e-01 70.3% 94.4%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.73 50.0 5.41e-01 70.3% 93.5%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.72 51.0 4.12e-01 73.4% 88.2%
4im0A04 1.20.1270.420 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.72 51.0 4.09e-01 72.7% 84.0%
3nftA00 1.20.1710.10 Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like 0.69 59.0 4.67e-01 92.2% 97.3%
5gj7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 52.0 4.98e-01 81.2% 66.9%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 61.0 6.09e-01 96.9% 94.8%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.67 60.0 5.85e-01 95.3% 89.8%
5an3A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 36.0 3.65e-01 75.0% 51.2%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.67 53.0 5.26e-01 85.2% 83.1%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 55.0 5.77e-01 89.1% 100.0%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.66 57.0 5.63e-01 90.6% 88.0%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.66 46.0 4.83e-01 76.6% 79.8%
3swhA01 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.66 47.0 4.29e-01 72.7% 74.5%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.66 54.0 5.68e-01 95.3% 96.6%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 47.0 3.72e-01 75.8% 88.2%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.65 55.0 5.78e-01 89.1% 99.1%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 54.0 5.62e-01 91.4% 95.8%
4gnkE00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.63 46.0 3.73e-01 74.2% 83.4%
4cbeA00 1.20.120.1640 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 56.0 4.71e-01 96.9% 58.4%
4uskA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.63 40.0 3.79e-01 88.3% 52.6%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.63 45.0 4.87e-01 96.1% 89.5%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.63 54.0 5.63e-01 97.7% 100.0%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.63 53.0 4.53e-01 93.0% 76.2%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.62 52.0 5.41e-01 93.8% 96.6%
5azpB01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.62 49.0 3.57e-01 84.4% 59.1%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 44.0 4.44e-01 71.9% 76.2%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.62 52.0 5.35e-01 89.8% 97.5%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.61 50.0 5.25e-01 89.8% 98.2%
6l1xA01 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.61 53.0 3.59e-01 97.7% 43.5%
4bg5B00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.61 50.0 4.26e-01 86.7% 74.9%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.61 46.0 4.33e-01 79.7% 76.3%
2cdqA02 1.20.120.1320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain 0.60 44.0 5.01e-01 86.7% 100.0%
4cgkA01 6.10.250.3150 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.60 48.0 4.03e-01 84.4% 95.8%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 46.0 4.51e-01 82.0% 75.4%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 51.0 5.17e-01 93.0% 97.7%
2hfsA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.59 38.0 3.65e-01 94.5% 56.2%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 36.0 3.50e-01 72.7% 53.4%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.58 45.0 4.86e-01 89.1% 99.1%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 41.0 4.35e-01 71.9% 87.2%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 42.0 4.37e-01 74.2% 86.3%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 42.0 4.69e-01 79.7% 98.0%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.57 44.0 3.68e-01 82.0% 80.3%
2gfnA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 39.0 3.47e-01 71.9% 57.3%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 42.0 3.90e-01 93.0% 64.6%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.55 48.0 4.31e-01 96.9% 68.5%
4a4kA01 1.20.1500.20 Mainly Alpha › Up-down Bundle › YheA-like fold › 0.54 32.0 3.35e-01 90.6% 62.8%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.54 47.0 4.76e-01 93.8% 96.0%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 39.0 3.99e-01 97.7% 75.8%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.52 39.0 4.21e-01 98.4% 91.1%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3605520 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.73 52.0 4.39e-01 72.7% 87.6%
3608166 1189.1.1.5 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › ESAG1 0.73 51.0 3.99e-01 71.9% 89.1%
4026597 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 65.0 5.48e-01 96.9% 85.4%
3562523 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.71 55.0 5.01e-01 82.0% 87.1%
3267622 601.1.1.37 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Frag1 0.71 61.0 6.14e-01 93.0% 95.4%
3509455 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.71 63.0 5.77e-01 96.1% 98.2%
3587197 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.70 64.0 6.08e-01 99.2% 98.7%
4872033 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 60.0 4.97e-01 93.8% 64.1%
4977102 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.68 40.0 4.10e-01 93.8% 59.2%
3840081 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 56.0 5.45e-01 90.6% 90.2%
5050919 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 46.0 4.98e-01 71.1% 87.3%
3496091 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 58.0 5.71e-01 95.3% 98.5%
3690392 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.65 58.0 5.15e-01 97.7% 73.5%
3902164 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.65 47.0 4.76e-01 74.2% 76.8%
3719434 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 48.0 4.86e-01 77.3% 88.0%
3496693 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.63 37.0 3.77e-01 70.3% 56.9%
3732719 601.1.1.25 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C 0.61 55.0 5.43e-01 99.2% 99.3%
3699444 3755.3.1.6 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Flagellar_rod 0.61 47.0 3.93e-01 81.2% 47.4%
4033032 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 52.0 5.05e-01 95.3% 100.0%
3917600 604.1.1.6 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_4 0.59 42.0 4.39e-01 74.2% 80.0%
3871543 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 45.0 4.48e-01 82.0% 83.1%
4952530 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.57 49.0 4.87e-01 95.3% 98.5%
3916044 3684.1.1.35 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › JMY 0.57 49.0 4.58e-01 93.8% 96.2%
3528346 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 44.0 4.11e-01 84.4% 67.9%
3263613 601.1.1.97 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DNA_repr_REX1B 0.55 48.0 4.54e-01 96.1% 93.5%
3481122 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 39.0 4.37e-01 82.0% 100.0%
3361109 604.1.1.100 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › NET2A_C 0.51 41.0 4.14e-01 84.4% 96.0%
D3 medium residues 109-347
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.68 37.0 4.63e-01 95.4% 84.4%
4iggB06 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 40.0 4.28e-01 99.2% 67.4%
1at9A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 52.0 5.35e-01 99.2% 89.1%
7cfmR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 58.0 5.63e-01 95.8% 95.8%
3am6A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 52.0 5.35e-01 100.0% 89.7%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.63 39.0 4.77e-01 94.6% 96.7%
7yu4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 56.0 5.46e-01 100.0% 87.5%
8g59R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 59.0 5.68e-01 100.0% 96.6%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 30.0 4.24e-01 81.6% 93.2%
7c4sB01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 57.0 5.43e-01 100.0% 85.5%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 28.0 4.13e-01 81.6% 94.5%
7akwA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 50.0 5.17e-01 98.7% 91.0%
7t7kA01 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.61 27.0 3.82e-01 97.9% 83.9%
1ciyA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.60 49.0 5.08e-01 95.0% 91.0%
3wfdB00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.59 54.0 4.39e-01 99.6% 69.0%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 33.0 3.86e-01 81.2% 75.7%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 41.0 4.51e-01 94.1% 90.1%
3ayfA01 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.56 52.0 3.93e-01 99.6% 58.2%
2rfqC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 39.0 4.47e-01 71.5% 99.4%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.55 39.0 4.25e-01 78.7% 87.6%
1xlyA00 1.20.200.20 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › She2 domain 0.53 41.0 4.22e-01 79.5% 97.8%
3snhA02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.52 29.0 3.09e-01 82.0% 59.3%
1dbhA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.51 42.0 4.45e-01 100.0% 98.1%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3940752 5001.1.1.60 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx 0.70 65.0 6.02e-01 99.6% 85.3%
3923570 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.69 65.0 5.93e-01 100.0% 83.3%
4961640 5001.1.1.292 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HisKA_7TM 0.69 59.0 5.97e-01 98.7% 90.0%
4024287 5001.1.1.81 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › THH1_TOM1-3_dom 0.69 64.0 5.99e-01 100.0% 88.3%
3930691 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.68 63.0 5.83e-01 100.0% 85.7%
3929661 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.66 62.0 5.76e-01 100.0% 84.7%
3189778 5001.1.1.88 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › STE2 0.66 62.0 5.92e-01 100.0% 88.4%
3931007 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.66 62.0 5.70e-01 100.0% 86.3%
3393621 5001.1.1.8 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII 0.65 58.0 5.63e-01 100.0% 85.4%
3215638 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.65 62.0 5.75e-01 100.0% 84.5%
3221129 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.65 60.0 5.51e-01 100.0% 85.8%
4033315 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.64 44.0 5.07e-01 100.0% 93.1%
3273711 5001.1.1.123 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF29575 0.64 60.0 5.13e-01 100.0% 74.4%
3941255 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.64 60.0 5.60e-01 99.2% 86.9%
3929151 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.64 59.0 5.36e-01 98.7% 78.8%
3396505 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.64 54.0 5.65e-01 95.4% 97.7%
3268150 5001.1.1.148 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Frizzled, PF29575 0.64 59.0 5.14e-01 100.0% 75.6%
3510487 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.64 59.0 5.18e-01 100.0% 92.1%
3926266 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.64 59.0 5.48e-01 100.0% 85.3%
3502948 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.64 59.0 5.35e-01 100.0% 81.6%
3932243 5001.1.1.60 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx 0.63 59.0 5.37e-01 100.0% 80.0%
3929423 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 59.0 5.40e-01 100.0% 83.3%
3895979 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 58.0 5.35e-01 100.0% 80.3%
3923749 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 58.0 5.45e-01 100.0% 87.5%
3509230 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 58.0 5.57e-01 100.0% 92.7%
3845241 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.63 58.0 5.37e-01 100.0% 85.2%
3245464 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.63 58.0 5.24e-01 100.0% 93.2%
3924629 5001.1.1.16 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt 0.63 58.0 5.28e-01 100.0% 82.2%
3408006 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.62 51.0 5.40e-01 96.7% 96.7%
3793879 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.62 58.0 5.08e-01 100.0% 82.3%
3241726 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.62 58.0 5.08e-01 100.0% 86.4%
3389297 5001.1.1.32 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a 0.60 53.0 5.10e-01 98.3% 82.1%
3513004 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.60 40.0 4.70e-01 95.0% 95.2%
4010554 5001.1.1.38 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › MASE4 0.60 53.0 5.29e-01 100.0% 92.5%
3901222 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.59 55.0 5.10e-01 99.6% 81.0%
3235122 5001.1.1.84 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz 0.59 53.0 5.07e-01 97.5% 83.9%
3262785 5001.1.1.79 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › YhhN 0.58 53.0 5.03e-01 97.9% 83.5%
4002271 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.58 54.0 4.63e-01 100.0% 85.8%
3444453 5001.1.1.8 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII 0.58 41.0 4.40e-01 82.4% 84.3%
3467855 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.57 40.0 4.63e-01 95.0% 97.7%
3735919 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.56 37.0 4.36e-01 77.0% 95.2%
4326711 601.1.2.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ 0.56 40.0 4.31e-01 79.5% 86.5%
4029735 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.54 47.0 3.40e-01 94.1% 73.7%
3625544 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 35.0 2.75e-01 90.0% 30.7%
54399 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.54 38.0 4.14e-01 77.8% 86.6%
4017571 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.53 45.0 4.36e-01 98.3% 78.9%
3404805 603.2.1.9 alpha bundles › STAT-like › STAT › STAT › 7tm_6 0.53 38.0 3.64e-01 73.6% 97.5%
4927824 1174.1.1.0 alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 0.51 40.0 4.18e-01 83.7% 88.2%