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IMGVR_UViG_3300005856_000048-3300005856-Ga0080005_1313801
Arc-VirIMGVR_UViG_3300005856_000048-3300005856-Ga0080005_1313801
Identity
- Kingdom:
- archaea
Quality
87.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 8-117
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2q9rA01 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.55 | 42.0 | 3.47e-01 | 79.1% | 55.4% |
| 4qmfB01 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.51 | 33.0 | 3.75e-01 | 98.2% | 89.0% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3785602 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.61 | 40.0 | 3.03e-01 | 75.5% | 27.5% |
| 3601525 | 603.1.1.176 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF5393 | 0.57 | 39.0 | 2.99e-01 | 70.9% | 88.3% |
| 3235832 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.55 | 43.0 | 3.05e-01 | 85.5% | 79.5% |
| 3882687 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 42.0 | 3.09e-01 | 84.5% | 77.6% |
| 3990199 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.54 | 42.0 | 3.01e-01 | 84.5% | 85.8% |
| 3573529 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.51 | 36.0 | 3.13e-01 | 72.7% | 95.3% |
| 4943281 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.50 | 38.0 | 2.97e-01 | 80.9% | 63.2% |
D2
high
residues 446-555
Domain cluster:
rep: IMGVR_UViG_3300026906_000061-3300026906-Ga0208683_1020067__D1-90
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5lbmA00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.65 | 42.0 | 4.76e-01 | 80.0% | 85.5% |
| 2gfnA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 51.0 | 4.22e-01 | 84.5% | 69.3% |
| 3aqtA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 50.0 | 4.21e-01 | 90.9% | 66.2% |
| 3tdoA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.61 | 48.0 | 3.65e-01 | 83.6% | 82.9% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 45.0 | 4.43e-01 | 78.2% | 88.1% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.60 | 47.0 | 4.73e-01 | 85.5% | 100.0% |
| 1st6A01 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.58 | 44.0 | 3.40e-01 | 80.9% | 69.0% |
| 3mklA00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.58 | 48.0 | 4.93e-01 | 90.0% | 100.0% |
| 2dg8D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 46.0 | 4.00e-01 | 86.4% | 75.7% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 47.0 | 3.70e-01 | 86.4% | 61.3% |
| 2oi8A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 46.0 | 3.81e-01 | 87.3% | 63.1% |
| 2wzkA02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.57 | 46.0 | 4.41e-01 | 87.3% | 99.2% |
| 6xiuA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.57 | 45.0 | 4.70e-01 | 85.5% | 100.0% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.57 | 49.0 | 4.86e-01 | 92.7% | 100.0% |
| 3peuB00 | 1.25.40.510 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › GLE1-like | 0.56 | 47.0 | 3.39e-01 | 89.1% | 48.8% |
| 4c91A03 | 1.20.58.2150 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 48.0 | 4.11e-01 | 94.5% | 97.8% |
| 2e9xD01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 40.0 | 3.74e-01 | 77.3% | 69.3% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 46.0 | 4.43e-01 | 94.5% | 80.5% |
| 3hwrA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.53 | 34.0 | 3.25e-01 | 89.1% | 55.0% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.51 | 37.0 | 3.70e-01 | 80.0% | 73.5% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4930182 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.67 | 51.0 | 4.16e-01 | 78.2% | 62.1% |
| 3199411 | 109.4.1.514 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps54 | 0.67 | 56.0 | 4.26e-01 | 90.9% | 65.4% |
| 3366621 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.66 | 46.0 | 4.02e-01 | 70.9% | 80.6% |
| 5069770 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.64 | 46.0 | 4.31e-01 | 74.5% | 89.6% |
| 3991822 | 109.4.1.17 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin | 0.62 | 55.0 | 3.92e-01 | 100.0% | 49.6% |
| 5073298 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.62 | 50.0 | 4.05e-01 | 85.5% | 90.2% |
| 3467802 | 603.1.1.226 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26740 | 0.62 | 51.0 | 4.68e-01 | 89.1% | 89.7% |
| 4132802 | 507.1.1.1 ↗ | alpha arrays › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB | 0.61 | 45.0 | 4.04e-01 | 76.4% | 92.7% |
| 3232833 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.60 | 47.0 | 3.40e-01 | 81.8% | 44.3% |
| 4008053 | 4168.1.1.7 ↗ | alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain › PF26769 | 0.60 | 50.0 | 4.36e-01 | 90.0% | 68.5% |
| 5050318 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.59 | 45.0 | 3.34e-01 | 79.1% | 49.1% |
| 3932846 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.59 | 48.0 | 3.94e-01 | 87.3% | 65.9% |
| 3674701 | 5086.1.1.11 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › UPF0114 | 0.59 | 43.0 | 3.83e-01 | 75.5% | 72.9% |
| 3846731 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.58 | 45.0 | 3.24e-01 | 84.5% | 50.0% |
| 3232159 | 5001.1.1.63 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab | 0.57 | 44.0 | 3.16e-01 | 81.8% | 50.8% |
| 3244951 | 109.4.1.17 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin | 0.56 | 48.0 | 3.23e-01 | 98.2% | 35.4% |
| 3601571 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.55 | 42.0 | 3.81e-01 | 80.0% | 86.9% |
| 3173091 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.54 | 41.0 | 3.70e-01 | 80.0% | 85.3% |
| 4438233 | 101.35.1.5 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH1 | 0.53 | 42.0 | 4.31e-01 | 85.5% | 97.1% |
| 3657736 | 101.35.1.19 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH2+RecX_HTH1 | 0.52 | 41.0 | 4.26e-01 | 90.9% | 91.4% |
| 3508301 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.51 | 42.0 | 3.62e-01 | 88.2% | 81.7% |
| 4294975 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.51 | 40.0 | 3.45e-01 | 85.5% | 88.3% |
| 3792040 | 109.4.1.1765 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF31007 | 0.50 | 41.0 | 3.16e-01 | 87.3% | 50.8% |
D3
high
residues 564-607
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.77 | 65.0 | 4.92e-01 | 100.0% | 79.3% |
| 5o5jT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.72 | 62.0 | 5.05e-01 | 100.0% | 63.5% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.71 | 59.0 | 4.58e-01 | 100.0% | 78.0% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.70 | 58.0 | 4.92e-01 | 100.0% | 75.9% |
| 2fe1A00 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.69 | 58.0 | 4.24e-01 | 100.0% | 50.0% |
| 3t69A02 | 3.30.420.310 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain | 0.69 | 57.0 | 3.71e-01 | 100.0% | 20.8% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.68 | 55.0 | 4.26e-01 | 100.0% | 77.8% |
| 3uj9A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.67 | 57.0 | 3.58e-01 | 100.0% | 86.8% |
| 1zmbA02 | 6.10.170.10 | Special › Helix non-globular › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › | 0.66 | 48.0 | 5.11e-01 | 88.6% | 97.2% |
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.66 | 49.0 | 4.06e-01 | 93.2% | 45.6% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.65 | 54.0 | 4.13e-01 | 100.0% | 76.3% |
| 2nn4A00 | 1.10.287.760 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like | 0.63 | 54.0 | 4.90e-01 | 100.0% | 88.7% |
| 1qd1B02 | 3.30.70.670 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Formiminotransferase, C-terminal subdomain | 0.63 | 45.0 | 3.16e-01 | 77.3% | 48.3% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.62 | 49.0 | 4.30e-01 | 88.6% | 94.0% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 45.0 | 3.85e-01 | 84.1% | 94.9% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.60 | 47.0 | 4.61e-01 | 88.6% | 93.9% |
| 7zh0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.60 | 47.0 | 2.81e-01 | 100.0% | 31.5% |
| 3gg7A00 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.58 | 48.0 | 3.09e-01 | 100.0% | 18.5% |
| 1rsoB00 | 1.10.287.650 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain | 0.58 | 42.0 | 4.06e-01 | 88.6% | 73.2% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.57 | 44.0 | 3.26e-01 | 88.6% | 73.0% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.57 | 46.0 | 4.23e-01 | 97.7% | 67.8% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.54 | 47.0 | 4.12e-01 | 97.7% | 95.3% |
| 1l1qA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 41.0 | 2.92e-01 | 100.0% | 66.9% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 43.0 | 3.55e-01 | 100.0% | 80.9% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4331928 | 375.1.9.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase | 0.83 | 64.0 | 4.64e-01 | 84.1% | 34.8% |
| 4509297 | 532.2.1.0 ↗ | alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains | 0.78 | 67.0 | 4.32e-01 | 100.0% | 50.7% |
| 4474310 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.76 | 65.0 | 5.43e-01 | 100.0% | 67.5% |
| 4181805 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.76 | 65.0 | 5.46e-01 | 100.0% | 65.4% |
| 4289855 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.75 | 65.0 | 5.79e-01 | 100.0% | 83.1% |
| 4270503 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.75 | 64.0 | 5.26e-01 | 100.0% | 63.5% |
| 4321884 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.75 | 65.0 | 5.14e-01 | 100.0% | 58.1% |
| 4095914 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.75 | 64.0 | 5.36e-01 | 100.0% | 67.5% |
| 4088690 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.75 | 65.0 | 5.38e-01 | 100.0% | 67.5% |
| 4063100 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.74 | 64.0 | 5.32e-01 | 100.0% | 67.5% |
| 3282520 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.68 | 52.0 | 4.55e-01 | 86.4% | 57.1% |
| 5054079 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.67 | 54.0 | 4.43e-01 | 88.6% | 50.0% |
| 5029911 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.64 | 54.0 | 5.01e-01 | 100.0% | 88.1% |
| 3723174 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.60 | 48.0 | 4.04e-01 | 88.6% | 53.3% |
| 4182121 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.60 | 50.0 | 2.96e-01 | 100.0% | 22.2% |
| 3170253 | 632.3.1.11 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain › SUV3_C | 0.60 | 51.0 | 4.37e-01 | 100.0% | 78.7% |
D4
medium
residues 215-300_323-354
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6s21B01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.53 | 46.0 | 3.29e-01 | 99.2% | 77.0% |
| 4upkA01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.52 | 46.0 | 3.14e-01 | 100.0% | 70.2% |
| 3e2dA01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.52 | 45.0 | 3.25e-01 | 99.2% | 87.7% |
| 4upiA01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.51 | 44.0 | 2.99e-01 | 98.3% | 66.5% |
| 3ed4C01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.51 | 44.0 | 3.18e-01 | 98.3% | 77.1% |
| 5eghB01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.51 | 45.0 | 3.45e-01 | 99.2% | 79.4% |
| 1u0mA01 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.51 | 41.0 | 3.48e-01 | 88.1% | 98.0% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4276821 | 314.1.1.1 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2 | 0.60 | 31.0 | 2.15e-01 | 71.2% | 15.0% |
| 4929238 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.57 | 26.0 | 3.22e-01 | 91.5% | 66.7% |
| 3215999 | 5001.1.1.111 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1, 7TM_GPCR_Srw | 0.55 | 41.0 | 2.93e-01 | 80.5% | 88.1% |
| 3606667 | 7515.1.1.0 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like | 0.50 | 44.0 | 3.48e-01 | 100.0% | 79.2% |
D5
medium
residues 301-322_355-388
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.81 | 57.0 | 3.84e-01 | 73.2% | 30.1% |
| 1lujB01 | 1.10.10.490 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Beta-catenin-interacting ICAT | 0.80 | 37.0 | 3.83e-01 | 85.7% | 47.2% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.75 | 68.0 | 5.26e-01 | 100.0% | 84.0% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.75 | 58.0 | 3.67e-01 | 82.1% | 19.9% |
| 2yevC00 | 6.10.280.110 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 57.0 | 5.47e-01 | 83.9% | 74.6% |
| 4h33A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 63.0 | 5.44e-01 | 100.0% | 73.6% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.72 | 55.0 | 5.21e-01 | 94.6% | 70.3% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.72 | 47.0 | 4.99e-01 | 75.0% | 77.6% |
| 2a3qA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.71 | 53.0 | 4.14e-01 | 78.6% | 46.0% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 56.0 | 5.20e-01 | 87.5% | 67.6% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.71 | 64.0 | 5.04e-01 | 100.0% | 51.8% |
| 3sjqC00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 57.0 | 4.97e-01 | 92.9% | 60.0% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 55.0 | 4.98e-01 | 85.7% | 71.4% |
| 1z0pA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 53.0 | 4.84e-01 | 89.3% | 61.6% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 53.0 | 5.05e-01 | 83.9% | 74.6% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 56.0 | 4.70e-01 | 91.1% | 100.0% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 52.0 | 4.78e-01 | 85.7% | 84.9% |
| 2cobA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.66 | 46.0 | 5.04e-01 | 75.0% | 93.2% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.66 | 58.0 | 5.11e-01 | 100.0% | 92.9% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 56.0 | 4.73e-01 | 92.9% | 56.7% |
| 1mhyG01 | 1.20.1280.10 | Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 1 | 0.66 | 51.0 | 4.82e-01 | 83.9% | 85.3% |
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.64 | 47.0 | 3.66e-01 | 80.4% | 43.5% |
| 3nkhA00 | 1.10.443.10 | Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core | 0.64 | 49.0 | 3.40e-01 | 91.1% | 24.0% |
| 1ax8A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.63 | 53.0 | 4.00e-01 | 92.9% | 46.9% |
| 3vfzB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 49.0 | 4.70e-01 | 83.9% | 81.0% |
| 4dgwB01 | 1.10.10.790 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module | 0.61 | 48.0 | 5.00e-01 | 96.4% | 100.0% |
| 2vf7B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 51.0 | 3.22e-01 | 100.0% | 45.4% |
| 2gomA00 | 1.10.10.1270 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV | 0.60 | 44.0 | 4.33e-01 | 82.1% | 86.9% |
| 8hk0A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.59 | 44.0 | 3.68e-01 | 89.3% | 54.6% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 40.0 | 3.85e-01 | 76.8% | 70.8% |
| 2ijeS00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.56 | 48.0 | 3.12e-01 | 94.6% | 21.9% |
| 3ktdD02 | 1.10.3660.10 | Mainly Alpha › Orthogonal Bundle › 6-phosphogluconate dehydrogenase C-terminal fold › 6-phosphogluconate dehydrogenase C-terminal like domain | 0.55 | 46.0 | 3.81e-01 | 96.4% | 76.1% |
| 1oxjA02 | 1.25.40.170 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Smaug, PHAT domain | 0.55 | 42.0 | 3.56e-01 | 89.3% | 62.4% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.54 | 41.0 | 3.47e-01 | 85.7% | 89.0% |
| 5dvwA00 | 1.20.120.1160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.51 | 44.0 | 3.38e-01 | 96.4% | 90.9% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4463205 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.81 | 60.0 | 3.47e-01 | 78.6% | 10.8% |
| 3611632 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.78 | 59.0 | 4.78e-01 | 80.4% | 61.0% |
| 3210948 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.77 | 59.0 | 5.20e-01 | 82.1% | 58.7% |
| 4801882 | 192.1.1.1 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › MCPsignal | 0.75 | 57.0 | 5.51e-01 | 82.1% | 78.1% |
| 3803573 | 7022.1.1.0 ↗ | alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein | 0.75 | 57.0 | 3.77e-01 | 92.9% | 21.4% |
| 3545645 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.72 | 57.0 | 4.95e-01 | 85.7% | 57.6% |
| 3944950 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 54.0 | 5.18e-01 | 85.7% | 69.2% |
| 5044572 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.72 | 62.0 | 5.08e-01 | 98.2% | 98.1% |
| 4042824 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.71 | 58.0 | 5.09e-01 | 87.5% | 63.7% |
| 3626122 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 52.0 | 5.09e-01 | 78.6% | 90.0% |
| 3485919 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.70 | 62.0 | 4.52e-01 | 100.0% | 83.9% |
| 4946898 | 375.1.9.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase | 0.70 | 54.0 | 4.90e-01 | 83.9% | 69.3% |
| 3214189 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 60.0 | 4.93e-01 | 98.2% | 98.1% |
| 4121104 | 5054.1.1.7 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › KdpA | 0.69 | 59.0 | 4.30e-01 | 100.0% | 34.8% |
| 4971500 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.69 | 56.0 | 4.36e-01 | 89.3% | 41.7% |
| 4982959 | 3922.1.1.357 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Auto_anti-p27 | 0.68 | 50.0 | 4.18e-01 | 80.4% | 47.0% |
| 3585354 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 53.0 | 4.52e-01 | 85.7% | 54.4% |
| 3355246 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.67 | 52.0 | 4.64e-01 | 85.7% | 63.7% |
| 4954372 | 2484.1.1.18 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 | 0.67 | 57.0 | 3.54e-01 | 91.1% | 93.7% |
| 2708 | 101.1.2.49 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C | 0.66 | 58.0 | 4.15e-01 | 100.0% | 84.0% |
| 3904047 | 9.26.1.0 ↗ | beta barrels › Lipocalins/Streptavidin | 0.66 | 50.0 | 3.47e-01 | 82.1% | 24.9% |
| 3372955 | 101.1.1.267 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › PF26138 | 0.66 | 50.0 | 3.97e-01 | 83.9% | 65.0% |
| 4024628 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.66 | 48.0 | 4.41e-01 | 76.8% | 85.7% |
| 4051951 | 605.2.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 | 0.66 | 49.0 | 4.26e-01 | 85.7% | 51.1% |
| 3483235 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.65 | 48.0 | 3.83e-01 | 80.4% | 69.6% |
| 3229124 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.65 | 50.0 | 3.77e-01 | 85.7% | 33.8% |
| 3840045 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.64 | 51.0 | 4.63e-01 | 92.9% | 73.8% |
| 5004578 | 101.1.1.545 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › DUF1699 | 0.64 | 45.0 | 4.47e-01 | 76.8% | 78.3% |
| 4441096 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.62 | 49.0 | 4.83e-01 | 91.1% | 85.0% |
| 3341091 | 101.35.1.6 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › A_thal_3526 | 0.57 | 41.0 | 3.99e-01 | 80.4% | 90.8% |
| 1030601 | 3143.1.2.1 ↗ | alpha complex topology › Rift Valley fever virus nucleocapsid protein-related › Rift Valley fever virus nucleocapsid protein-related › Rift Valley fever virus nucleocapsid protein › Tenui_N | 0.53 | 43.0 | 2.93e-01 | 100.0% | 74.5% |