Back to structures

IMGVR_UViG_3300005856_000091-3300005856-Ga0080005_14280040

Arc-Vir

IMGVR_UViG_3300005856_000091-3300005856-Ga0080005_14280040

Quality

93.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-82
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u89A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 63.0 5.34e-01 100.0% 88.5%
3e3vA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 37.0 4.39e-01 89.0% 75.0%
2qgmA03 1.20.1440.30 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain 0.66 54.0 4.89e-01 91.5% 76.7%
1fp3A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.65 45.0 2.86e-01 72.0% 23.6%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.63 46.0 4.60e-01 79.3% 86.2%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 43.0 4.02e-01 72.0% 90.6%
1yc9A01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.62 55.0 3.63e-01 98.8% 68.2%
6e1kA01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 53.0 4.82e-01 98.8% 75.0%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 41.0 4.36e-01 100.0% 78.4%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 41.0 3.88e-01 70.7% 94.1%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.60 51.0 5.11e-01 96.3% 97.7%
2w96A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.58 46.0 4.15e-01 85.4% 77.9%
1kqfC00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.57 40.0 3.02e-01 74.4% 59.3%
2i53A01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.57 45.0 3.80e-01 86.6% 62.2%
3evyA00 1.20.58.910 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 38.0 3.88e-01 70.7% 100.0%
1xo0A01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.56 38.0 3.51e-01 72.0% 61.3%
5cqgA03 1.10.10.2210 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.55 32.0 3.35e-01 85.4% 60.8%
3zc4A01 1.20.120.1610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 44.0 4.33e-01 96.3% 82.2%
1dqeA00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.55 44.0 3.86e-01 93.9% 92.7%
2gfhA02 1.20.120.710 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain 0.54 45.0 4.46e-01 92.7% 96.5%
4q5qB00 1.20.1050.130 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 42.0 3.32e-01 86.6% 79.8%
2pqrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 44.0 4.25e-01 90.2% 88.2%
6axfA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.52 41.0 3.69e-01 87.8% 88.9%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3221349 3289.1.1.8 alpha complex topology › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Strumpellin 0.78 71.0 3.95e-01 100.0% 10.8%
5058485 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 52.0 4.67e-01 76.8% 63.5%
3374812 150.1.1.124 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › THU_Piezo1 0.69 59.0 5.09e-01 95.1% 92.3%
4016796 509.1.1.0 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain 0.65 52.0 5.06e-01 87.8% 81.1%
3236773 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 56.0 4.76e-01 100.0% 97.8%
3681341 650.1.1.8 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › Ovate 0.62 37.0 4.12e-01 96.3% 75.4%
5043950 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.62 49.0 5.04e-01 86.6% 100.0%
3783862 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.62 43.0 3.01e-01 72.0% 73.5%
5032080 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 44.0 4.02e-01 79.3% 62.6%
3540152 509.1.1.8 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › ZSWIM4-8_C 0.60 42.0 3.86e-01 75.6% 64.0%
4363138 192.29.1.125 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cytochrom_C_asm 0.58 50.0 3.58e-01 100.0% 74.9%
9794 4244.1.1.2 a/b three-layered sandwiches › EreA/ChaN-like › EreA/ChaN-like › EreA/ChaN-like › Erythro_esteras 0.58 51.0 3.30e-01 100.0% 23.6%
3589723 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 40.0 3.53e-01 73.2% 84.8%
3939274 604.3.1.11 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 0.56 40.0 3.43e-01 78.0% 93.1%
D2 medium residues 83-167
PDB
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1lkoA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 57.0 4.71e-01 76.5% 86.9%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.77 57.0 4.83e-01 77.6% 56.9%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.76 69.0 5.65e-01 100.0% 73.9%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.74 49.0 4.63e-01 76.5% 57.0%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 51.0 4.02e-01 76.5% 86.2%
1u8vB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 62.0 4.65e-01 97.6% 78.4%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.71 52.0 5.23e-01 77.6% 90.8%
2z1qB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 61.0 5.22e-01 95.3% 81.6%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.70 51.0 4.16e-01 76.5% 81.5%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.68 50.0 4.12e-01 77.6% 61.5%
3f7cA00 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.67 56.0 4.33e-01 94.1% 49.7%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.67 49.0 5.19e-01 77.6% 90.5%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 47.0 3.71e-01 72.9% 77.5%
2lmgA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 48.0 5.08e-01 77.6% 97.3%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.64 45.0 4.47e-01 100.0% 70.1%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 43.0 4.12e-01 70.6% 98.1%
1jalA03 1.10.150.300 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain 0.64 50.0 5.12e-01 87.1% 90.1%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 43.0 3.91e-01 70.6% 83.1%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.62 42.0 3.73e-01 87.1% 47.6%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 41.0 4.38e-01 100.0% 79.7%
2aplA01 1.10.8.330 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like 0.57 39.0 4.33e-01 71.8% 97.1%
5t3wA00 1.20.120.1160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 42.0 3.64e-01 83.5% 74.5%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.54 38.0 3.67e-01 100.0% 63.6%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.52 38.0 3.98e-01 76.5% 88.3%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.51 36.0 3.51e-01 74.1% 81.2%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3221349 3289.1.1.8 alpha complex topology › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Nck-associated protein 1/Cytoplasmic FMR1-interacting protein 1 › Strumpellin 0.78 69.0 3.88e-01 97.6% 10.5%
3263668 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.77 67.0 6.27e-01 95.3% 100.0%
3913234 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.73 64.0 5.49e-01 97.6% 86.7%
3247352 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.73 64.0 5.63e-01 97.6% 92.0%
3868831 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.72 63.0 5.07e-01 97.6% 77.6%
4211332 633.10.1.35 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › NKAIN 0.72 63.0 5.61e-01 97.6% 92.5%
5018283 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.72 64.0 6.08e-01 100.0% 96.0%
3360919 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.71 62.0 5.24e-01 97.6% 75.7%
4157794 174.1.1.40 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF5373 0.68 59.0 5.02e-01 96.5% 92.9%
3333417 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.68 41.0 4.04e-01 100.0% 56.7%
4034406 632.15.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › CompInhib_SCIN 0.66 49.0 4.92e-01 77.6% 78.8%
3477916 174.1.1.19 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DoxX_2 0.65 55.0 4.89e-01 97.6% 95.4%
3232658 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 55.0 4.82e-01 97.6% 83.1%
3193435 3755.3.1.451 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › BUD22 0.63 54.0 4.71e-01 97.6% 88.1%
3249566 135.1.1.1 alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › G-alpha 0.62 52.0 4.75e-01 97.6% 85.0%
4203629 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.61 52.0 4.89e-01 98.8% 90.0%
4028068 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.58 41.0 3.61e-01 76.5% 86.4%
4237524 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.52 47.0 4.63e-01 100.0% 98.9%
2799599 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.51 39.0 3.97e-01 100.0% 81.4%