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IMGVR_UViG_3300005977_000013-3300005977-Ga0081474_12475439
Arc-VirIMGVR_UViG_3300005977_000013-3300005977-Ga0081474_12475439
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-60
Domain cluster:
representative
CATH (39)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ospO01 | 2.40.128.160 | Mainly Beta › Beta Barrel › Lipocalin › C1 set domains (antibody constant domain-like) | 0.70 | 56.0 | 4.63e-01 | 86.7% | 92.4% |
| 3vsmA03 | 2.60.40.4340 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.68 | 46.0 | 3.94e-01 | 70.0% | 45.7% |
| 3ligA02 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.68 | 53.0 | 3.76e-01 | 83.3% | 73.4% |
| 3immA00 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.68 | 55.0 | 3.79e-01 | 88.3% | 68.5% |
| 1w2tA02 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.67 | 52.0 | 3.97e-01 | 83.3% | 70.1% |
| 1genA00 | 2.110.10.10 | Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain | 0.67 | 48.0 | 3.33e-01 | 76.7% | 86.0% |
| 1iwmA00 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.67 | 51.0 | 3.61e-01 | 81.7% | 93.2% |
| 3h3lC00 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.66 | 55.0 | 3.74e-01 | 93.3% | 64.6% |
| 4amwA01 | 2.60.40.1760 | Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) | 0.65 | 50.0 | 3.14e-01 | 83.3% | 45.3% |
| 1w4tA01 | 3.30.2140.10 | Alpha Beta › 2-Layer Sandwich › Arylamine N-acetyltransferase fold › Arylamine N-acetyltransferase | 0.65 | 48.0 | 3.40e-01 | 78.3% | 73.6% |
| 4jqtA01 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.64 | 52.0 | 3.59e-01 | 88.3% | 72.6% |
| 3e9mB02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.64 | 49.0 | 3.37e-01 | 81.7% | 46.5% |
| 5dzeA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.64 | 51.0 | 3.57e-01 | 88.3% | 70.4% |
| 2vqrA01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.63 | 54.0 | 3.26e-01 | 100.0% | 59.2% |
| 3b77A01 | 2.30.29.50 | Mainly Beta › Roll › PH-domain like › Bacterial Pleckstrin homology domain | 0.63 | 44.0 | 3.73e-01 | 73.3% | 65.0% |
| 2h0bC00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.63 | 52.0 | 3.63e-01 | 90.0% | 57.9% |
| 3pveA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.62 | 51.0 | 3.66e-01 | 90.0% | 57.7% |
| 6hgcA01 | 3.40.532.10 | Alpha Beta › 3-Layer(aba) Sandwich › Ubiquitin C-terminal Hydrolase UCH-l3 › Peptidase C12, ubiquitin carboxyl-terminal hydrolase | 0.62 | 46.0 | 3.24e-01 | 80.0% | 73.8% |
| 3cxbA01 | 3.30.2440.10 | Alpha Beta › 2-Layer Sandwich › Secreted effector protein SifA fold › Secreted effector protein SifA | 0.61 | 46.0 | 3.71e-01 | 81.7% | 57.4% |
| 3a7sA00 | 3.40.532.10 | Alpha Beta › 3-Layer(aba) Sandwich › Ubiquitin C-terminal Hydrolase UCH-l3 › Peptidase C12, ubiquitin carboxyl-terminal hydrolase | 0.61 | 45.0 | 3.14e-01 | 81.7% | 68.1% |
| 2yj6A02 | 3.40.1110.10 | Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N | 0.61 | 44.0 | 3.82e-01 | 78.3% | 75.8% |
| 4guzA01 | 3.30.2140.10 | Alpha Beta › 2-Layer Sandwich › Arylamine N-acetyltransferase fold › Arylamine N-acetyltransferase | 0.60 | 48.0 | 3.40e-01 | 86.7% | 73.5% |
| 1pz7A00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.58 | 47.0 | 3.36e-01 | 90.0% | 59.6% |
| 1p32B00 | 3.10.280.10 | Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein | 0.58 | 41.0 | 2.98e-01 | 83.3% | 25.7% |
| 6xofA01 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.58 | 50.0 | 3.32e-01 | 98.3% | 69.6% |
| 2n01B00 | 2.60.40.2500 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.58 | 40.0 | 3.25e-01 | 71.7% | 62.3% |
| 5vxzA01 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.57 | 45.0 | 3.19e-01 | 88.3% | 53.9% |
| 4hs5A00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.56 | 46.0 | 3.80e-01 | 88.3% | 92.4% |
| 8cukB01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.56 | 45.0 | 2.78e-01 | 86.7% | 74.7% |
| 1yprA00 | 3.30.450.30 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic | 0.56 | 41.0 | 3.25e-01 | 78.3% | 38.4% |
| 2v43A01 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.56 | 46.0 | 3.33e-01 | 93.3% | 43.2% |
| 2x4jA01 | 2.30.30.600 | Mainly Beta › Roll › SH3 type barrels. › | 0.54 | 42.0 | 3.62e-01 | 90.0% | 90.2% |
| 2g7jA00 | 3.90.1150.40 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Protein of unknown function DUF2002 | 0.53 | 37.0 | 3.14e-01 | 76.7% | 76.8% |
| 2jpiA00 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.53 | 38.0 | 3.43e-01 | 83.3% | 67.7% |
| 4jpdA00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.52 | 39.0 | 3.34e-01 | 85.0% | 56.9% |
| 1itvA00 | 2.110.10.10 | Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain | 0.51 | 37.0 | 2.69e-01 | 80.0% | 46.2% |
| 1nr0A02 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.51 | 40.0 | 2.75e-01 | 100.0% | 65.4% |
| 1ukfA00 | 3.90.70.20 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › | 0.51 | 42.0 | 3.05e-01 | 98.3% | 74.5% |
| 6bm0A01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.51 | 45.0 | 2.75e-01 | 100.0% | 64.3% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4949914 | 246.2.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos | 0.70 | 48.0 | 3.07e-01 | 71.7% | 67.9% |
| 3755672 | 6129.1.1.1 ↗ | beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD | 0.68 | 44.0 | 3.04e-01 | 80.0% | 19.5% |
| 3489849 | 5.1.4.74 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Vps16_N | 0.68 | 54.0 | 3.17e-01 | 85.0% | 59.4% |
| 4302938 | 292.2.1.0 ↗ | a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain | 0.68 | 45.0 | 3.99e-01 | 73.3% | 48.2% |
| 3217785 | 10.1.1.4 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin | 0.67 | 52.0 | 3.87e-01 | 85.0% | 74.2% |
| 3788785 | 5.1.5.18 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Vps16_N | 0.66 | 49.0 | 2.88e-01 | 80.0% | 62.3% |
| 5068365 | 10.1.1.21 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › 3keto-disac_hyd | 0.65 | 51.0 | 3.66e-01 | 85.0% | 73.1% |
| 3518179 | 10.1.1.1 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_1 | 0.65 | 53.0 | 4.08e-01 | 90.0% | 75.6% |
| 3220737 | 207.1.1.52 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FBA_2 | 0.65 | 45.0 | 2.87e-01 | 70.0% | 16.1% |
| 2389074 | 10.1.1.27 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Alginate_lyase2 | 0.64 | 56.0 | 3.68e-01 | 98.3% | 78.8% |
| 3994301 | 10.1.1.17 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 | 0.64 | 50.0 | 3.53e-01 | 83.3% | 56.5% |
| 3248113 | 219.1.1.6 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Acetyltransf_2 | 0.64 | 51.0 | 3.27e-01 | 86.7% | 85.8% |
| 3888075 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.63 | 44.0 | 3.04e-01 | 73.3% | 81.0% |
| 3896034 | 10.1.1.17 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 | 0.63 | 51.0 | 3.57e-01 | 88.3% | 53.8% |
| 4260682 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.63 | 46.0 | 3.27e-01 | 78.3% | 53.5% |
| 168845 | 219.1.1.6 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Acetyltransf_2 | 0.63 | 49.0 | 3.12e-01 | 83.3% | 64.8% |
| 3400083 | 5.1.5.18 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Vps16_N | 0.62 | 49.0 | 3.13e-01 | 85.0% | 88.7% |
| 3253551 | 219.1.1.6 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Acetyltransf_2 | 0.62 | 50.0 | 3.23e-01 | 88.3% | 69.6% |
| 5000881 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.62 | 47.0 | 3.50e-01 | 81.7% | 39.4% |
| 3961809 | 9.11.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like › MliC | 0.62 | 48.0 | 4.39e-01 | 85.0% | 100.0% |
| 3894967 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.62 | 44.0 | 3.05e-01 | 75.0% | 86.5% |
| 4964003 | 241.1.1.29 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › DUF5813 | 0.61 | 43.0 | 3.15e-01 | 95.0% | 28.4% |
| 3843929 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.61 | 48.0 | 3.30e-01 | 83.3% | 58.9% |
| 3601202 | 5.1.4.220 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_2nd | 0.61 | 47.0 | 2.94e-01 | 83.3% | 87.5% |
| 3665510 | 5.1.4.74 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Vps16_N | 0.61 | 48.0 | 3.02e-01 | 86.7% | 80.9% |
| 3408722 | 633.23.1.20 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Atthog | 0.61 | 43.0 | 3.04e-01 | 73.3% | 83.3% |
| 3237575 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.61 | 48.0 | 3.14e-01 | 88.3% | 40.7% |
| 3418340 | 5.1.5.18 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Vps16_N | 0.60 | 48.0 | 2.99e-01 | 86.7% | 80.9% |
| 3524259 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.60 | 47.0 | 3.24e-01 | 83.3% | 59.5% |
| 4032337 | 4964.1.1.0 ↗ | alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I | 0.60 | 49.0 | 3.62e-01 | 91.7% | 49.7% |
| 4026175 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.59 | 51.0 | 3.54e-01 | 96.7% | 68.8% |
| 3946655 | 7515.1.1.22 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › CBP_BcsG | 0.59 | 49.0 | 3.03e-01 | 93.3% | 55.9% |
| 4969673 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.58 | 49.0 | 3.13e-01 | 95.0% | 83.2% |
| 3874152 | 5.1.1.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 4-bladed › Hemopexin | 0.58 | 45.0 | 3.13e-01 | 86.7% | 89.3% |
| 3317337 | 5.1.5.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed | 0.58 | 47.0 | 2.89e-01 | 91.7% | 83.2% |
| 3176337 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.58 | 47.0 | 2.92e-01 | 91.7% | 21.9% |
| 3621723 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.56 | 44.0 | 2.89e-01 | 91.7% | 20.4% |
| 3923721 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.54 | 44.0 | 2.87e-01 | 98.3% | 49.6% |
| 3227921 | 5.1.4.175 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_IFT122_2nd | 0.54 | 43.0 | 2.97e-01 | 98.3% | 67.0% |
| 3724695 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.54 | 46.0 | 2.98e-01 | 100.0% | 22.0% |
| 3489990 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.51 | 42.0 | 3.07e-01 | 93.3% | 79.4% |
D2
medium
residues 61-139
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vw4L02 | 1.10.246.170 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.58 | 41.0 | 4.03e-01 | 74.7% | 90.6% |
| 8b4hA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.52 | 39.0 | 3.09e-01 | 79.7% | 51.2% |
| 2nscA01 | 3.30.70.1050 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Trigger factor ribosome-binding domain | 0.52 | 32.0 | 3.29e-01 | 73.4% | 64.1% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3827046 | 284.1.3.1 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › SNF5 | 0.65 | 46.0 | 4.44e-01 | 74.7% | 75.6% |
| 3649733 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.60 | 42.0 | 3.28e-01 | 73.4% | 45.4% |
| 4161177 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.59 | 49.0 | 3.04e-01 | 94.9% | 48.6% |
| 3289865 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.58 | 48.0 | 3.41e-01 | 89.9% | 82.5% |
| 4181971 | 533.1.1.1 ↗ | alpha bundles › Arp2/3 complex 21 kDa subunit ARPC3 › Arp2/3 complex 21 kDa subunit ARPC3 › Arp2/3 complex 21 kDa subunit ARPC3 › P21-Arc | 0.55 | 38.0 | 3.33e-01 | 93.7% | 47.5% |
| 3688535 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 42.0 | 2.68e-01 | 83.5% | 16.5% |
| 4873837 | 103.2.1.2 ↗ | alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone | 0.53 | 43.0 | 4.23e-01 | 94.9% | 95.4% |
| 3401010 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 41.0 | 3.77e-01 | 97.5% | 93.0% |