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IMGVR_UViG_3300006308_000160-3300006308-Ga0068470_11360514

Arc-Vir

IMGVR_UViG_3300006308_000160-3300006308-Ga0068470_11360514

Quality

95.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-82
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wj7A01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.73 46.0 5.10e-01 80.3% 81.7%
2x1dA02 1.10.10.2120 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.65 40.0 4.08e-01 72.4% 62.2%
2damA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.62 37.0 3.90e-01 76.3% 65.7%
1q02A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.56 36.0 3.99e-01 89.5% 94.2%
5h92B03 3.30.413.10 Alpha Beta › 2-Layer Sandwich › Sulfite Reductase Hemoprotein; domain 1 › Sulfite Reductase Hemoprotein, domain 1 0.56 41.0 3.40e-01 80.3% 96.7%
3hruB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 43.0 3.73e-01 90.8% 86.4%
2l4mA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 28.0 2.97e-01 73.7% 55.1%
2mgwA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.53 34.0 3.77e-01 89.5% 96.2%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4292511 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.70 66.0 3.91e-01 98.7% 44.9%
4264204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.70 66.0 4.30e-01 98.7% 79.3%
4931685 101.1.2.21 alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repress 0.54 44.0 3.69e-01 92.1% 89.3%
4938267 206.1.3.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_2 0.50 36.0 2.72e-01 77.6% 39.0%
D2 medium residues 84-149_216-304
PDB
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2cfaA01 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.84 47.0 4.91e-01 81.9% 59.7%
3ah5B00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.84 66.0 5.93e-01 81.9% 73.9%
4p5aC00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.81 67.0 5.80e-01 85.8% 76.7%
2af6A01 3.30.70.3180 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.80 61.0 6.61e-01 85.8% 91.6%
1kq4A00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.77 64.0 5.79e-01 87.1% 72.9%
3d7iB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.60 33.0 4.13e-01 86.5% 85.7%
3bh7B02 3.30.70.141 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleoside diphosphate kinase-like domain 0.53 34.0 3.84e-01 76.1% 84.3%
1af5A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.50 27.0 2.94e-01 74.8% 59.5%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4264204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.99 86.0 6.81e-01 88.4% 66.5%
4292511 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.99 97.0 6.47e-01 100.0% 41.9%
5024486 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.95 89.0 7.61e-01 96.1% 76.4%
4102574 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 73.0 6.16e-01 84.5% 71.7%
4504275 325.1.1.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › CO dehydrogenase molybdoprotein N-domain-like 0.87 45.0 6.31e-01 79.4% 98.8%
4964267 304.54.1.0 a+b two layers › Alpha-beta plaits › CcmK-like › CcmK-like 0.87 45.0 5.20e-01 79.4% 68.7%
4152367 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.86 75.0 5.74e-01 89.7% 74.5%
4988219 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.85 70.0 5.82e-01 85.2% 70.0%
4930760 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.85 74.0 6.05e-01 90.3% 60.8%
5001652 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.85 74.0 6.06e-01 91.0% 61.5%
4992830 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.84 75.0 6.44e-01 91.6% 71.1%
4933142 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 67.0 5.76e-01 83.2% 63.5%
5077404 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 73.0 6.11e-01 91.0% 63.3%
134624 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 69.0 5.75e-01 85.8% 69.9%
4300356 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 65.0 5.92e-01 81.3% 73.0%
4628182 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 68.0 5.58e-01 84.5% 65.5%
4943595 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 73.0 6.33e-01 92.3% 68.9%
4133204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.82 72.0 6.04e-01 90.3% 68.3%
4246528 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.82 73.0 6.11e-01 92.3% 70.1%
143031 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.82 67.0 5.99e-01 84.5% 74.0%
4060791 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.82 68.0 5.60e-01 85.8% 66.3%
4982008 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.81 68.0 6.17e-01 87.1% 72.5%
1716752 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.81 67.0 5.79e-01 85.8% 75.7%
1007250 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.80 64.0 5.77e-01 81.9% 71.1%
5054516 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.80 63.0 5.86e-01 80.6% 80.0%
5046119 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.80 65.0 5.81e-01 84.5% 68.3%
4134497 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.77 67.0 5.77e-01 90.3% 63.5%
4941740 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.77 74.0 5.02e-01 100.0% 38.6%
5054515 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.77 63.0 5.63e-01 85.8% 65.7%
4345249 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.76 63.0 5.48e-01 86.5% 60.9%
4926808 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.76 63.0 5.51e-01 86.5% 62.3%
5024487 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.76 63.0 5.60e-01 86.5% 66.2%
5018373 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.74 60.0 5.29e-01 83.2% 69.0%
5069296 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.74 70.0 5.79e-01 100.0% 65.5%
5029299 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.72 63.0 5.61e-01 91.6% 68.6%
3230196 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 28.0 3.16e-01 78.7% 56.7%
4990704 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.57 35.0 4.15e-01 81.9% 88.6%
5022358 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.52 29.0 3.33e-01 76.8% 72.2%
3249652 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.51 29.0 3.09e-01 74.8% 60.0%
3873832 109.4.1.84 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › API5 0.51 35.0 3.40e-01 82.6% 62.9%
D3 medium residues 150-215
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1l5aA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.64 50.0 3.55e-01 83.3% 63.9%
3pjxA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 46.0 3.36e-01 78.8% 43.6%
6nyyE01 1.20.58.760 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Peptidase M41 0.62 52.0 3.87e-01 93.9% 44.5%
1p65A00 6.10.140.90 Special › Helix non-globular › Helix Hairpins › 0.61 37.0 3.93e-01 97.0% 68.4%
1ga6A00 3.40.50.200 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain 0.60 49.0 3.04e-01 89.4% 76.7%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 42.0 3.53e-01 74.2% 46.6%
1f02T00 4.10.820.10 Few Secondary Structures › Irregular › Translocated Intimin Receptor; Chain T › Translocated intimin receptor, central domain 0.60 46.0 4.61e-01 81.8% 100.0%
1gzsB00 1.10.4120.10 Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › SopE-like, GEF domain 0.58 47.0 3.44e-01 86.4% 63.6%
7c2xA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.58 40.0 2.71e-01 74.2% 37.0%
3hwcA01 1.10.3140.10 Mainly Alpha › Orthogonal Bundle › 4-hydroxybutyryl-coa dehydratase, domain 1 › 4-hydroxybutyryl-coa dehydratase, domain 1 0.57 50.0 3.83e-01 98.5% 44.9%
1dosA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.56 47.0 3.04e-01 100.0% 91.3%
1vyiA00 1.20.120.820 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Phosphoprotein, C-terminal domain 0.55 47.0 4.02e-01 100.0% 58.6%
3u6uC00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.54 47.0 3.17e-01 98.5% 24.4%
4ayoA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.54 44.0 2.79e-01 97.0% 92.9%
3gyuA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.54 44.0 3.06e-01 93.9% 26.0%
4o7iA01 3.30.540.10 Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 0.53 41.0 3.15e-01 100.0% 33.0%
3cvvA02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 39.0 3.20e-01 81.8% 87.0%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.52 43.0 3.36e-01 90.9% 97.9%
6yttA01 1.10.8.190 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Carbon monoxide dehydrogenase alpha subunit. Chain M, domain 1 0.52 42.0 3.63e-01 86.4% 82.0%
4dsfA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.52 42.0 3.58e-01 89.4% 97.3%
3aqoA01 3.30.70.3400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 35.0 3.33e-01 71.2% 72.5%
4bpuC00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.51 42.0 2.71e-01 97.0% 86.1%
3uqcD02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.50 39.0 3.00e-01 84.8% 47.1%
ECOD (50)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4030787 605.1.1.303 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Terminase_4 0.73 44.0 3.79e-01 84.8% 40.0%
3244833 3914.1.1.2 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer 0.71 63.0 3.59e-01 100.0% 9.4%
4380337 102.1.3.25 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain › DUF932 0.68 55.0 4.48e-01 84.8% 95.6%
3369845 3379.1.1.2 extended segments › Photosystem II reaction center protein ycf12 › Photosystem II reaction center protein ycf12 › Photosystem II reaction center protein ycf12 › DUF3339 0.68 52.0 5.24e-01 81.8% 93.8%
4008902 4268.2.1.20 alpha duplicates or obligate multimers › EspA/CesA-like › EspA chaperone CesA › EspA chaperone CesA › DUF932 0.68 54.0 4.47e-01 84.8% 95.6%
3306562 5063.1.1.5 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › DUF3339 0.68 54.0 5.46e-01 86.4% 93.8%
None 0.67 50.0 2.84e-01 86.4% 6.9%
3611776 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.65 58.0 4.53e-01 100.0% 53.6%
3438456 5063.1.1.5 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › DUF3339 0.65 51.0 5.15e-01 86.4% 95.4%
5066039 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.64 57.0 3.40e-01 100.0% 60.6%
4525842 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.63 45.0 2.93e-01 75.8% 34.3%
4993051 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.63 54.0 3.22e-01 100.0% 70.7%
3478703 192.29.1.24 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM237 0.62 49.0 3.43e-01 83.3% 83.6%
3597508 101.1.17.0 alpha arrays › HTH › HTH › FF domain 0.62 49.0 4.66e-01 87.9% 73.8%
3936741 304.28.1.5 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › NPC1_MLD 0.61 46.0 3.16e-01 83.3% 67.5%
4972215 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.59 42.0 2.92e-01 75.8% 28.1%
5040870 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.59 50.0 3.54e-01 98.5% 64.4%
4039355 2004.1.1.258 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA,AAA_2 0.59 48.0 2.98e-01 87.9% 16.9%
5041410 2006.1.1.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Trehalose_PPase 0.59 40.0 2.67e-01 71.2% 22.3%
5083960 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.58 46.0 3.40e-01 98.5% 31.1%
3785380 5051.1.1.6 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Aa_trans 0.58 46.0 2.82e-01 86.4% 75.2%
5083115 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.58 50.0 3.67e-01 98.5% 45.9%
4607322 604.39.1.1 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › CbiM 0.58 49.0 3.38e-01 92.4% 68.0%
4939027 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.58 41.0 3.33e-01 74.2% 60.8%
4251053 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.57 44.0 3.06e-01 100.0% 23.1%
4115648 3671.1.1.1 alpha duplicates or obligate multimers › Translocated intimin receptor Tir extracellular domain › Translocated intimin receptor Tir extracellular domain › Translocated intimin receptor Tir extracellular domain › Tir_receptor_M 0.57 48.0 4.46e-01 97.0% 75.3%
3959389 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.56 39.0 2.59e-01 74.2% 99.0%
3309226 145.1.1.3 alpha arrays › F-box domain › F-box domain › F-box domain › F-box-like 0.56 45.0 3.76e-01 87.9% 71.3%
3544534 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 40.0 3.75e-01 77.3% 66.3%
3862747 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.55 40.0 3.66e-01 77.3% 62.4%
5083220 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.54 45.0 2.79e-01 98.5% 24.3%
5019055 3281.1.1.1 alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M 0.54 48.0 2.80e-01 100.0% 68.5%
3848684 2484.1.1.104 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.53 45.0 3.16e-01 100.0% 84.5%
3788426 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 47.0 2.68e-01 93.9% 59.7%
3970671 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.53 37.0 3.61e-01 72.7% 70.7%
3222232 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.53 39.0 2.87e-01 83.3% 71.2%
5081050 4275.1.1.11 alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › SU10_adaptor 0.53 45.0 3.31e-01 100.0% 60.0%
3939641 2484.1.1.104 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.53 45.0 3.18e-01 100.0% 70.6%
5050144 4018.1.1.2 a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P 0.53 42.0 3.10e-01 92.4% 32.2%
3897588 2484.1.1.104 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.53 45.0 3.13e-01 100.0% 82.8%
3391689 5054.1.1.1 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Lig_chan 0.53 45.0 3.38e-01 100.0% 44.4%
3777935 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.53 44.0 2.86e-01 92.4% 39.7%
5007173 2004.1.1.293 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 0.53 40.0 2.83e-01 100.0% 23.7%
4030496 5081.1.1.2 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DER1 0.53 43.0 3.23e-01 95.5% 34.7%
3986621 5069.1.1.2 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ni_hydr_CYTB 0.52 40.0 3.03e-01 86.4% 62.9%
None 0.52 45.0 2.89e-01 97.0% 99.4%
4681683 3719.1.1.1 alpha bundles › Imelysin peptidase-like › Imelysin peptidase-like › Imelysin peptidase-like › Peptidase_M75 0.52 43.0 3.02e-01 100.0% 99.2%
3775826 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.51 41.0 3.34e-01 97.0% 81.4%
3727891 633.23.1.36 alpha bundles › Bromodomain-like › Claudin › Claudin › PF30929 0.51 40.0 2.97e-01 90.9% 33.0%
4028109 3525.1.1.0 alpha arrays › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain 0.51 37.0 3.82e-01 80.3% 84.6%
D4 medium residues 305-381
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wgfA01 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.62 40.0 4.72e-01 81.8% 98.1%
1v64A00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.60 44.0 3.97e-01 77.9% 75.9%
3zfvA02 3.30.70.1900 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 43.0 3.51e-01 87.0% 64.1%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.54 48.0 3.41e-01 98.7% 57.3%
2go7A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.52 39.0 4.17e-01 81.8% 97.0%
4lzgA01 1.10.150.110 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like 0.51 37.0 3.51e-01 77.9% 87.1%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5029299 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.94 79.0 5.52e-01 92.2% 32.4%
4926808 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.92 87.0 6.02e-01 100.0% 35.5%
5024487 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.92 80.0 5.64e-01 94.8% 33.8%
4345249 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 81.0 5.60e-01 100.0% 32.9%
4943595 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.71 52.0 3.78e-01 94.8% 27.1%
3989900 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.66 43.0 3.33e-01 74.0% 31.9%
4949793 101.1.2.652 alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repr_C 0.63 47.0 4.01e-01 85.7% 47.7%
4926960 101.1.2.652 alpha arrays › HTH › HTH › winged helix domain › Fe_dep_repr_C 0.61 48.0 4.10e-01 87.0% 85.4%
4020548 7579.1.1.58 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DUF829 0.59 42.0 2.92e-01 77.9% 28.1%
3983080 5065.1.1.1 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 0.53 40.0 2.81e-01 83.1% 54.4%
3313232 207.1.1.258 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › WH_DRP 0.53 39.0 3.27e-01 83.1% 92.3%
3679428 109.4.1.1146 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_PUB 0.52 36.0 2.45e-01 71.4% 22.7%
D5 medium residues 382-512
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02511.21 best Thy1 54.9 1.40e-14 95.4% 69.6%
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2cfaA01 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.93 58.0 5.58e-01 100.0% 57.6%
4p5aC00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.89 84.0 6.86e-01 100.0% 74.9%
1kq4A00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.88 84.0 7.05e-01 100.0% 70.4%
3ah5B00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.82 78.0 6.54e-01 100.0% 71.5%
2af6A01 3.30.70.3180 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.77 66.0 6.63e-01 100.0% 87.8%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 32.0 4.10e-01 93.1% 91.9%
1wi8A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.56 33.0 4.08e-01 90.1% 98.7%
3bh7B02 3.30.70.141 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleoside diphosphate kinase-like domain 0.52 38.0 3.95e-01 93.1% 82.6%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4926808 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.99 98.0 7.84e-01 100.0% 59.5%
5029299 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.99 97.0 7.92e-01 100.0% 62.4%
5024487 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.98 95.0 7.83e-01 100.0% 63.3%
4345249 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.97 94.0 7.56e-01 100.0% 58.2%
4292511 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.97 94.0 6.07e-01 100.0% 27.0%
4943595 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.92 88.0 7.15e-01 100.0% 63.6%
5077404 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.92 88.0 6.89e-01 100.0% 58.8%
4628182 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.91 87.0 6.75e-01 100.0% 62.7%
1007250 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.91 87.0 7.34e-01 100.0% 69.2%
4133204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.91 87.0 6.86e-01 100.0% 61.3%
4152367 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 86.0 6.29e-01 100.0% 64.2%
4060791 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 86.0 6.67e-01 100.0% 62.7%
4982008 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 86.0 7.27e-01 100.0% 67.5%
4988219 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 86.0 6.71e-01 100.0% 66.8%
5066566 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.90 85.0 6.98e-01 100.0% 70.5%
5001652 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 85.0 6.57e-01 100.0% 56.5%
4246528 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 85.0 6.70e-01 100.0% 63.5%
4930760 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 84.0 6.53e-01 100.0% 56.9%
4992830 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 84.0 6.84e-01 100.0% 65.3%
1716752 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.89 84.0 6.83e-01 100.0% 73.9%
4102574 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.88 84.0 6.66e-01 100.0% 70.0%
134624 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 83.0 6.52e-01 100.0% 67.9%
4933143 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 82.0 6.92e-01 100.0% 71.9%
4264204 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 82.0 6.24e-01 100.0% 62.9%
4941740 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 82.0 5.37e-01 100.0% 28.5%
4977743 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.86 73.0 6.39e-01 100.0% 62.2%
5054516 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.85 81.0 7.08e-01 100.0% 78.9%
5046119 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.85 81.0 6.75e-01 100.0% 66.3%
4955043 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.85 78.0 7.43e-01 97.7% 84.0%
5024486 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.84 79.0 6.49e-01 100.0% 66.7%
4134497 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 79.0 6.34e-01 100.0% 58.3%
5069296 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 77.0 6.08e-01 100.0% 52.5%
4300356 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.83 78.0 6.64e-01 100.0% 71.5%
143031 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.82 78.0 6.53e-01 100.0% 71.2%
4933142 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.82 76.0 6.21e-01 100.0% 61.7%
5054515 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.78 72.0 6.07e-01 100.0% 62.4%
5018373 842.1.1.0 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 0.76 71.0 5.96e-01 100.0% 66.2%
4169525 304.110.1.4 a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › UPF0176_N 0.57 33.0 3.78e-01 90.8% 76.8%
5022358 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.52 33.0 3.51e-01 94.7% 71.3%
3741142 309.1.1.17 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16, Peptidase_M16_C, Peptidase_M16_M, PqqF-like_C_4 0.52 40.0 2.41e-01 81.7% 33.3%
2093009 304.12.1.1 a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › Ribosomal_S6 0.51 36.0 4.08e-01 93.1% 99.0%