←Back to structures
IMGVR_UViG_3300006332_001304-3300006332-Ga0068500_11033976
Arc-VirIMGVR_UViG_3300006332_001304-3300006332-Ga0068500_11033976
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-53
Domain cluster:
rep: IMGVR_UViG_3300020357_000105-3300020357-Ga0211611_10017308__D1-54
D2
high
residues 104-189
Domain cluster:
rep: IMGVR_UViG_3300006315_000216-3300006315-Ga0068487_102099712__D126-194
D3
high
residues 198-369
Domain cluster:
rep: GU071101.1__ADO98784.1__PHM1_160__00160__D114-301
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1a41A02 | 1.20.120.380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 | 0.56 | 30.0 | 3.90e-01 | 96.5% | 92.6% |
| 1rdfA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.56 | 25.0 | 3.57e-01 | 94.8% | 91.0% |
| 2lwxA00 | 1.10.8.840 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ribosome-associated complex head domain | 0.54 | 27.0 | 3.60e-01 | 76.2% | 90.9% |
| 2pejA00 | 1.10.1200.210 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX | 0.52 | 20.0 | 2.51e-01 | 78.5% | 54.1% |
| 3h1nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 24.0 | 2.82e-01 | 70.3% | 59.2% |
D4
medium
residues 379-448_560-580
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4z48A00 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.63 | 49.0 | 3.62e-01 | 83.5% | 75.0% |
| 3gxwC00 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.61 | 44.0 | 4.29e-01 | 100.0% | 68.0% |
| 3hdjA01 | 3.30.1780.10 | Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 | 0.60 | 52.0 | 4.62e-01 | 100.0% | 77.9% |
| 3klxB00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.59 | 41.0 | 3.33e-01 | 72.5% | 45.9% |
| 3otlA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.58 | 43.0 | 3.64e-01 | 78.0% | 69.3% |
| 4l9cA00 | 3.40.1000.30 | Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › | 0.58 | 51.0 | 4.38e-01 | 100.0% | 80.0% |
| 8aimG01 | 3.10.450.20 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Bacteriophage PBS2, uracil-glycosylase inhibitor | 0.56 | 38.0 | 4.04e-01 | 82.4% | 79.0% |
| 3zqsA01 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.54 | 42.0 | 4.27e-01 | 95.6% | 85.2% |
| 1odhA01 | 2.20.25.670 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › GCM domain, large subdomain | 0.53 | 31.0 | 3.44e-01 | 82.4% | 73.2% |
| 3k44B00 | 3.30.2450.30 | Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › | 0.52 | 40.0 | 3.57e-01 | 85.7% | 85.0% |
| 2az4A01 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.51 | 39.0 | 2.86e-01 | 83.5% | 76.8% |
| 1ywuA00 | 2.40.10.220 | Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains | 0.51 | 37.0 | 3.36e-01 | 76.9% | 86.4% |
| 4qdgA02 | 2.60.40.2090 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.50 | 43.0 | 3.79e-01 | 95.6% | 90.4% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3426677 | 252.1.1.1 ↗ | a+b two layers › DNA-binding domain › Methyl-CpG-binding domain, MBD › Methyl-CpG-binding domain, MBD › MBD | 0.65 | 41.0 | 4.12e-01 | 89.0% | 60.6% |
| 3407414 | 5.1.4.269 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40, HELP, Beta-prop_EML | 0.64 | 47.0 | 3.23e-01 | 78.0% | 52.5% |
| 3962288 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.60 | 42.0 | 3.73e-01 | 71.4% | 60.0% |
| 3938164 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.59 | 40.0 | 4.64e-01 | 70.3% | 100.0% |
| 3887495 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.59 | 41.0 | 3.82e-01 | 75.8% | 56.5% |
| 3278294 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.59 | 43.0 | 3.97e-01 | 76.9% | 66.4% |
| 3179848 | 241.15.1.2 ↗ | a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › PI31_Prot_N | 0.57 | 50.0 | 4.42e-01 | 100.0% | 76.3% |
| 4013994 | 708.1.2.6 ↗ | beta complex topology › ETN0001 domain-like › ETN0001 domain-like › Mss4-like › GFA | 0.57 | 35.0 | 3.30e-01 | 74.7% | 48.7% |
| 3217673 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.56 | 43.0 | 4.14e-01 | 83.5% | 76.2% |
| 3954390 | 331.3.1.5 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc | 0.56 | 41.0 | 3.50e-01 | 76.9% | 56.1% |
| 5013679 | 3369.1.1.0 ↗ | beta meanders › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 | 0.55 | 48.0 | 4.56e-01 | 100.0% | 80.9% |
| 3212364 | 5.1.5.27 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › APEH_N | 0.55 | 47.0 | 3.06e-01 | 98.9% | 66.4% |
| 3783250 | 5.1.4.16 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CPSF_A | 0.55 | 47.0 | 3.25e-01 | 97.8% | 56.4% |
| 3241959 | 4026.1.1.0 ↗ | a+b three layers › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) | 0.54 | 34.0 | 3.22e-01 | 75.8% | 48.7% |
| 3972673 | 331.3.1.9 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › AHSA1 | 0.54 | 44.0 | 3.73e-01 | 89.0% | 59.4% |
| 3840029 | 883.1.1.0 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like | 0.53 | 39.0 | 3.63e-01 | 76.9% | 66.1% |
| 3280054 | 331.3.1.11 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 | 0.53 | 48.0 | 4.01e-01 | 100.0% | 69.3% |
| 3364063 | 295.1.1.3 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA | 0.52 | 41.0 | 3.61e-01 | 85.7% | 76.4% |
| 5021156 | 5.1.3.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed | 0.52 | 45.0 | 3.54e-01 | 97.8% | 81.5% |
| 1189179 | 2484.1.1.12 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Acetate_kinase | 0.51 | 39.0 | 3.13e-01 | 97.8% | 39.4% |
| 3939294 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.50 | 43.0 | 2.93e-01 | 98.9% | 87.0% |
D5
medium
residues 449-559
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5dqqA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 40.0 | 3.83e-01 | 76.6% | 57.6% |
| 2qe9B01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.56 | 45.0 | 4.03e-01 | 86.5% | 90.5% |
| 1st6A02 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.56 | 48.0 | 3.82e-01 | 99.1% | 44.9% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 43.0 | 3.88e-01 | 86.5% | 68.4% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 42.0 | 3.79e-01 | 86.5% | 67.1% |
| 2chnB03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.52 | 36.0 | 3.17e-01 | 72.1% | 95.6% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 46.0 | 4.40e-01 | 99.1% | 94.6% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 41.0 | 3.81e-01 | 86.5% | 67.4% |
| 1wpbB02 | 1.10.3190.10 | Mainly Alpha › Orthogonal Bundle › yfbu gene product, domain 2 › yfbu gene product, domain 2 | 0.51 | 37.0 | 3.74e-01 | 76.6% | 91.1% |
| 3c18A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 42.0 | 4.21e-01 | 99.1% | 86.4% |
| 3dyjA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.51 | 44.0 | 3.93e-01 | 99.1% | 75.3% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.50 | 37.0 | 3.72e-01 | 84.7% | 78.0% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4982527 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.64 | 49.0 | 5.09e-01 | 93.7% | 89.0% |
| 4626741 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.62 | 47.0 | 4.98e-01 | 93.7% | 93.7% |
| 4024517 | 101.1.1.64 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › tRNA_bind_2 | 0.61 | 46.0 | 4.60e-01 | 96.4% | 78.3% |
| 3440168 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.60 | 45.0 | 4.51e-01 | 79.3% | 80.9% |
| 5046322 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.59 | 41.0 | 4.77e-01 | 87.4% | 100.0% |
| 3222373 | 605.4.1.18 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF29357 | 0.57 | 42.0 | 4.65e-01 | 89.2% | 98.8% |
| 5012658 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.57 | 41.0 | 4.52e-01 | 86.5% | 93.3% |
| 3464503 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.56 | 43.0 | 4.05e-01 | 81.1% | 71.9% |
| 3215515 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.56 | 43.0 | 4.64e-01 | 82.9% | 100.0% |
| 3923707 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.55 | 40.0 | 4.23e-01 | 78.4% | 87.4% |
| None | — | 0.55 | 39.0 | 3.25e-01 | 87.4% | 42.6% | |
| 3892397 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.55 | 42.0 | 3.08e-01 | 80.2% | 75.3% |
| 3540024 | 5001.1.1.3 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 | 0.55 | 45.0 | 3.36e-01 | 88.3% | 50.4% |
| 3700264 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.55 | 46.0 | 4.42e-01 | 94.6% | 93.1% |
| 4001280 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.54 | 39.0 | 3.47e-01 | 89.2% | 52.9% |
| 3887645 | 633.21.1.10 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL | 0.54 | 42.0 | 4.05e-01 | 84.7% | 74.6% |
| 3871867 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.54 | 48.0 | 4.44e-01 | 98.2% | 83.6% |
| 3769571 | 1076.1.1.6 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › DUF2053 | 0.54 | 47.0 | 3.76e-01 | 96.4% | 89.7% |
| 3913281 | 3755.3.1.123 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin | 0.54 | 44.0 | 3.87e-01 | 86.5% | 85.0% |
| 4977057 | 3960.1.1.0 ↗ | alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain | 0.54 | 46.0 | 4.63e-01 | 100.0% | 94.8% |
| 4208157 | 5069.1.2.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Respiratory nitrate reductase 1 gamma chain › Nitrate_red_gam | 0.53 | 38.0 | 2.86e-01 | 73.0% | 92.6% |
| 3874821 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 42.0 | 3.32e-01 | 84.7% | 51.5% |
| 3968650 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.53 | 43.0 | 4.39e-01 | 86.5% | 90.5% |
| 3582803 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.53 | 46.0 | 4.55e-01 | 95.5% | 100.0% |
| 3940795 | 109.4.1.102 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › WAPL | 0.53 | 37.0 | 2.47e-01 | 73.0% | 35.2% |
| 3802240 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.53 | 42.0 | 4.42e-01 | 88.3% | 95.0% |
| 3967074 | 601.3.1.15 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27543 | 0.53 | 42.0 | 4.15e-01 | 97.3% | 80.0% |
| 3601986 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.52 | 40.0 | 3.50e-01 | 84.7% | 54.5% |
| 5075878 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.52 | 36.0 | 4.14e-01 | 84.7% | 98.8% |
| 3618557 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.51 | 39.0 | 4.25e-01 | 100.0% | 98.9% |
| 4351650 | 5050.1.1.23 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › CLN3 | 0.51 | 41.0 | 3.28e-01 | 86.5% | 95.5% |
| 3880919 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.51 | 40.0 | 3.70e-01 | 85.6% | 64.2% |