←Back to structures
IMGVR_UViG_3300006875_004413-3300006875-Ga0075473_100052652
Arc-VirIMGVR_UViG_3300006875_004413-3300006875-Ga0075473_100052652
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 23-262
Domain cluster:
rep: IMGVR_UViG_3300039190_000305-3300039190-Ga0399989_003201_3_1937__D82-97_167-336
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02518.32 best | HATPase_c | 27.4 | 5.30e-06 | 57.1% | 73.0% |
D2
high
residues 279-406
Domain cluster:
rep: DNA_gyrase_subunit_B__YP_009352802__Kaumoebavirus_Viruses.__X__D311-415
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00204.32 best | DNA_gyraseB | 75.1 | 7.00e-21 | 97.7% | 61.5% |
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1qzrA02 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.96 | 89.0 | 9.15e-01 | 100.0% | 99.2% |
| 3zkbI02 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.83 | 79.0 | 7.22e-01 | 100.0% | 83.7% |
| 3lnuA02 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.82 | 78.0 | 7.12e-01 | 100.0% | 87.0% |
| 4hy1A02 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.80 | 76.0 | 6.99e-01 | 100.0% | 86.7% |
| 3cwvA02 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.73 | 67.0 | 6.32e-01 | 98.4% | 86.1% |
| 1z5bB03 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.66 | 57.0 | 5.47e-01 | 94.5% | 83.2% |
| 8d8lE01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.65 | 36.0 | 4.23e-01 | 90.6% | 77.9% |
| 2aj4B01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.59 | 50.0 | 4.03e-01 | 91.4% | 58.1% |
| 1xhkA00 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.59 | 47.0 | 4.12e-01 | 91.4% | 57.8% |
| 3pyfA01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.56 | 47.0 | 4.42e-01 | 90.6% | 74.2% |
| 3hkmB00 | 3.30.230.70 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain | 0.56 | 43.0 | 3.66e-01 | 89.8% | 49.3% |
| 3gonA01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.56 | 47.0 | 4.09e-01 | 90.6% | 63.4% |
| 4gx0A01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 31.0 | 3.41e-01 | 71.1% | 67.0% |
| 3ltoA01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.55 | 47.0 | 4.17e-01 | 91.4% | 70.6% |
| 1nz0D00 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.54 | 38.0 | 4.04e-01 | 90.6% | 82.9% |
| 2wp8B00 | 3.30.230.70 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain | 0.54 | 40.0 | 3.35e-01 | 92.2% | 44.7% |
| 1oypA01 | 3.30.230.70 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain | 0.53 | 44.0 | 3.72e-01 | 95.3% | 53.3% |
| 4emeA01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.53 | 38.0 | 2.87e-01 | 75.0% | 68.5% |
| 1e3hA03 | 3.30.230.70 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain | 0.53 | 44.0 | 3.74e-01 | 93.8% | 54.5% |
| 2je6A01 | 3.30.230.70 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain | 0.52 | 44.0 | 3.54e-01 | 93.8% | 51.7% |
| 7ylrA01 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.51 | 32.0 | 3.50e-01 | 71.9% | 75.2% |
| 1rybA00 | 3.40.50.1470 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase | 0.51 | 39.0 | 3.44e-01 | 79.7% | 94.1% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 29.0 | 3.45e-01 | 88.3% | 81.6% |
| 4kx7A02 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.50 | 37.0 | 3.01e-01 | 77.3% | 39.8% |
| 2gs8A01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.50 | 42.0 | 3.80e-01 | 90.6% | 67.6% |
ECOD (83)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4641709 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.96 | 93.0 | 8.09e-01 | 100.0% | 73.9% |
| 3799215 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.95 | 93.0 | 8.32e-01 | 100.0% | 80.0% |
| 3275256 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.95 | 93.0 | 8.21e-01 | 100.0% | 76.5% |
| 3513708 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.95 | 92.0 | 8.39e-01 | 100.0% | 81.2% |
| 3585145 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.95 | 92.0 | 8.39e-01 | 100.0% | 81.9% |
| 4000834 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.94 | 91.0 | 8.21e-01 | 100.0% | 79.4% |
| 3220683 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.93 | 90.0 | 8.09e-01 | 100.0% | 84.2% |
| 3433616 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.92 | 88.0 | 8.06e-01 | 99.2% | 80.6% |
| 4027043 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.86 | 81.0 | 7.19e-01 | 100.0% | 80.6% |
| 4261801 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.86 | 81.0 | 6.96e-01 | 100.0% | 75.3% |
| 4234522 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.85 | 81.0 | 7.22e-01 | 100.0% | 84.1% |
| 3807571 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.85 | 80.0 | 7.09e-01 | 100.0% | 81.1% |
| 3970715 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.84 | 79.0 | 7.05e-01 | 100.0% | 81.7% |
| 4339883 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.84 | 80.0 | 6.92e-01 | 100.0% | 81.6% |
| 3964340 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.84 | 80.0 | 6.90e-01 | 100.0% | 80.5% |
| 4288775 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.84 | 79.0 | 6.95e-01 | 100.0% | 80.6% |
| 4945732 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.84 | 79.0 | 7.00e-01 | 100.0% | 80.0% |
| 4380841 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.83 | 78.0 | 6.96e-01 | 100.0% | 81.1% |
| 3967155 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.83 | 78.0 | 6.95e-01 | 100.0% | 80.6% |
| 4207771 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.83 | 78.0 | 6.91e-01 | 100.0% | 81.1% |
| 4298571 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.82 | 77.0 | 6.74e-01 | 100.0% | 80.0% |
| 3594648 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.81 | 77.0 | 7.06e-01 | 100.0% | 81.9% |
| 4040519 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.81 | 76.0 | 6.94e-01 | 100.0% | 79.4% |
| 1388837 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.81 | 74.0 | 7.06e-01 | 96.9% | 86.3% |
| 341211 | 212.1.1.2 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB | 0.73 | 67.0 | 6.33e-01 | 99.2% | 86.8% |
| 4065638 | 212.1.1.19 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › ACP | 0.69 | 45.0 | 5.00e-01 | 90.6% | 83.0% |
| 5033236 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.67 | 59.0 | 4.30e-01 | 93.8% | 39.4% |
| 5044842 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.67 | 59.0 | 4.87e-01 | 93.8% | 60.5% |
| 5037280 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.67 | 58.0 | 4.98e-01 | 93.8% | 65.9% |
| 4956606 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.67 | 58.0 | 5.05e-01 | 93.8% | 64.1% |
| 4941612 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.67 | 58.0 | 4.77e-01 | 93.8% | 57.0% |
| 4966371 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.67 | 58.0 | 4.38e-01 | 93.8% | 42.3% |
| 4584919 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.67 | 58.0 | 4.99e-01 | 93.8% | 65.0% |
| 4443422 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.67 | 58.0 | 4.97e-01 | 93.8% | 65.0% |
| 4972803 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.66 | 58.0 | 4.95e-01 | 93.8% | 65.0% |
| 4661396 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.66 | 57.0 | 4.74e-01 | 93.8% | 55.1% |
| 4028943 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.66 | 59.0 | 4.96e-01 | 99.2% | 65.0% |
| 5023191 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.65 | 55.0 | 4.95e-01 | 93.8% | 67.6% |
| 5044782 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.64 | 56.0 | 4.87e-01 | 93.8% | 64.7% |
| 4957148 | 212.1.1.22 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans | 0.63 | 55.0 | 4.69e-01 | 93.8% | 64.5% |
| 5081565 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.60 | 50.0 | 4.33e-01 | 87.5% | 71.6% |
| 3557551 | 212.1.1.24 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 | 0.60 | 50.0 | 5.04e-01 | 96.9% | 89.2% |
| 4529995 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.60 | 50.0 | 4.60e-01 | 90.6% | 70.6% |
| 4480000 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.59 | 44.0 | 4.72e-01 | 90.6% | 90.9% |
| 4209812 | 212.1.1.8 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P | 0.58 | 40.0 | 4.30e-01 | 90.6% | 81.8% |
| 4984187 | 212.1.1.20 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Fae | 0.58 | 49.0 | 4.35e-01 | 90.6% | 75.1% |
| 3602349 | 212.1.1.18 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Lon_C | 0.58 | 46.0 | 4.77e-01 | 91.4% | 89.2% |
| 3991620 | 212.1.1.25 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › MVD-like_N | 0.58 | 48.0 | 4.05e-01 | 86.7% | 73.7% |
| 3798325 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.58 | 43.0 | 3.97e-01 | 82.8% | 59.4% |
| 4947776 | 212.1.1.20 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Fae | 0.58 | 49.0 | 4.60e-01 | 90.6% | 89.7% |
| 4947770 | 212.1.1.18 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Lon_C | 0.57 | 48.0 | 4.81e-01 | 90.6% | 90.0% |
| 3869716 | 212.1.1.24 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 | 0.57 | 51.0 | 4.89e-01 | 100.0% | 85.3% |
| None | — | 0.56 | 46.0 | 4.05e-01 | 87.5% | 70.4% | |
| 3784150 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.56 | 46.0 | 4.80e-01 | 89.8% | 96.5% |
| 3597333 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.56 | 47.0 | 3.83e-01 | 90.6% | 56.7% |
| 4977874 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.56 | 46.0 | 4.13e-01 | 87.5% | 69.1% |
| None | — | 0.55 | 45.0 | 4.03e-01 | 86.7% | 73.9% | |
| 5054490 | 4961.1.1.1 ↗ | a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 | 0.55 | 24.0 | 3.59e-01 | 85.9% | 94.5% |
| 3705514 | 212.1.1.4 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N,GalKase_gal_bdg | 0.55 | 46.0 | 3.77e-01 | 90.6% | 55.0% |
| 4927937 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.55 | 45.0 | 3.41e-01 | 87.5% | 42.0% |
| 4014103 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.55 | 45.0 | 3.92e-01 | 86.7% | 72.1% |
| 1202332 | 212.1.1.25 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › MVD-like_N | 0.55 | 47.0 | 4.25e-01 | 91.4% | 74.7% |
| 3838926 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.55 | 46.0 | 4.18e-01 | 90.6% | 72.9% |
| 4513587 | 212.1.1.8 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P | 0.54 | 36.0 | 3.96e-01 | 89.8% | 82.9% |
| 5001215 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.54 | 46.0 | 4.15e-01 | 89.8% | 68.8% |
| 4239515 | 212.1.1.8 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P | 0.54 | 39.0 | 4.12e-01 | 89.8% | 86.4% |
| 4078116 | 212.1.1.25 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › MVD-like_N | 0.54 | 44.0 | 3.78e-01 | 87.5% | 65.4% |
| 4270774 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.54 | 45.0 | 4.23e-01 | 90.6% | 75.0% |
| 4272791 | 212.1.1.8 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P | 0.54 | 38.0 | 3.99e-01 | 91.4% | 81.7% |
| 4368625 | 212.1.1.8 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P | 0.53 | 42.0 | 4.27e-01 | 89.8% | 86.2% |
| 5015926 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.53 | 43.0 | 4.22e-01 | 90.6% | 81.4% |
| 4995330 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.52 | 43.0 | 3.89e-01 | 86.7% | 68.2% |
| 4993605 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.52 | 41.0 | 4.41e-01 | 81.2% | 100.0% |
| 3740359 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.52 | 44.0 | 4.22e-01 | 90.6% | 89.7% |
| 4947798 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.52 | 44.0 | 4.00e-01 | 90.6% | 70.0% |
| 152905 | 212.1.1.10 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › RNase_PH | 0.52 | 44.0 | 3.92e-01 | 93.8% | 63.8% |
| 3624072 | 212.1.1.10 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › RNase_PH | 0.52 | 43.0 | 4.04e-01 | 93.8% | 73.5% |
| 3506843 | 212.1.1.10 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › RNase_PH | 0.52 | 44.0 | 4.11e-01 | 93.8% | 74.4% |
| 4953487 | 231.1.2.0 ↗ | a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › DmpA/ArgJ | 0.52 | 44.0 | 3.80e-01 | 93.0% | 63.5% |
| 3281465 | 231.1.2.2 ↗ | a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › DmpA/ArgJ › Peptidase_S58 | 0.51 | 43.0 | 3.13e-01 | 92.2% | 43.6% |
| 4932339 | 212.1.1.10 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › RNase_PH | 0.51 | 43.0 | 3.91e-01 | 94.5% | 66.1% |
| 4486517 | 212.1.1.8 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P | 0.51 | 39.0 | 3.93e-01 | 93.8% | 81.4% |
| 4075516 | 212.1.1.8 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P | 0.51 | 41.0 | 4.06e-01 | 89.1% | 83.0% |
D3
high
residues 428-561_601-685
Domain cluster:
rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D385-517_553-621_640-664
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01751.29 best | Toprim | 37.1 | 4.20e-09 | 50.7% | 84.4% |
| PF16898.11 | TOPRIM_C | 84.8 | 8.10e-24 | 38.4% | 66.4% |
D4
high
residues 1033-1081_1097-1141
Domain cluster:
rep: KM209246.1__AIM51491.1__HQ82_0234__00002__D56-167
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 31.8 | 1.00e-07 | 100.0% | 18.8% |
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8gccA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.93 | 85.0 | 8.17e-01 | 94.7% | 86.5% |
| 1bgwA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.91 | 84.0 | 7.89e-01 | 96.8% | 94.5% |
| 3qx3A04 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.89 | 81.0 | 7.91e-01 | 94.7% | 94.0% |
| 4yvoA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.85 | 38.0 | 3.50e-01 | 92.6% | 34.5% |
| 1zvuA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.78 | 72.0 | 6.23e-01 | 100.0% | 67.9% |
| 3lpxA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.76 | 70.0 | 6.83e-01 | 98.9% | 98.1% |
| 4z4qA04 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.76 | 66.0 | 6.82e-01 | 98.9% | 98.9% |
| 5jazA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.74 | 33.0 | 3.38e-01 | 98.9% | 44.0% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.73 | 39.0 | 3.49e-01 | 98.9% | 37.2% |
| 1eo0A00 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.68 | 29.0 | 3.22e-01 | 96.8% | 46.8% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 36.0 | 3.43e-01 | 100.0% | 42.1% |
| 5mv9A01 | 1.25.40.530 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain | 0.68 | 36.0 | 2.90e-01 | 86.2% | 27.8% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 39.0 | 3.90e-01 | 98.9% | 54.1% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 40.0 | 4.03e-01 | 100.0% | 58.8% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.63 | 34.0 | 3.36e-01 | 95.7% | 47.5% |
| 7p2yd01 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.63 | 49.0 | 4.86e-01 | 85.1% | 81.8% |
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.63 | 36.0 | 3.46e-01 | 95.7% | 49.1% |
| 5ermB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.62 | 36.0 | 2.49e-01 | 100.0% | 16.6% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 41.0 | 3.82e-01 | 100.0% | 55.9% |
| 3ezhA00 | 1.20.120.960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain | 0.60 | 55.0 | 5.14e-01 | 100.0% | 99.1% |
| 4issA02 | 1.20.58.1700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 46.0 | 5.01e-01 | 97.9% | 100.0% |
| 3o39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 37.0 | 3.75e-01 | 98.9% | 62.5% |
| 3tbiB02 | 6.10.140.1670 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 44.0 | 4.34e-01 | 100.0% | 74.0% |
| 2doeA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.58 | 40.0 | 4.20e-01 | 70.2% | 79.5% |
| 4usaA02 | 1.10.150.120 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › [2Fe-2S]-binding domain | 0.58 | 43.0 | 4.02e-01 | 78.7% | 79.8% |
| 7y3eA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.57 | 51.0 | 3.35e-01 | 100.0% | 56.7% |
| 3ppbA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 43.0 | 3.50e-01 | 83.0% | 53.2% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.55 | 49.0 | 3.75e-01 | 100.0% | 91.4% |
| 2b8iA00 | 1.20.1280.100 | Mainly Alpha › Up-down Bundle › Monooxygenase › Pas factor, saposin domain | 0.55 | 39.0 | 4.21e-01 | 81.9% | 89.6% |
| 1ni7A00 | 3.90.1010.10 | Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › | 0.55 | 37.0 | 3.24e-01 | 70.2% | 77.2% |
| 5k7fA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 44.0 | 3.87e-01 | 87.2% | 78.3% |
| 4dvyP03 | 1.20.120.1270 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CagA exotoxin domain III | 0.54 | 49.0 | 4.09e-01 | 100.0% | 60.4% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.54 | 41.0 | 3.48e-01 | 79.8% | 66.2% |
| 1t98A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 39.0 | 4.09e-01 | 79.8% | 95.4% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.52 | 41.0 | 4.41e-01 | 89.4% | 94.0% |
| 1np7A02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 34.0 | 3.13e-01 | 71.3% | 52.9% |
| 2f8lA01 | 1.10.150.470 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.50 | 35.0 | 3.78e-01 | 87.2% | 85.2% |
ECOD (62)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3276180 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.97 | 94.0 | 7.07e-01 | 100.0% | 67.7% |
| 3328306 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.97 | 94.0 | 7.13e-01 | 100.0% | 65.3% |
| 3718739 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.97 | 94.0 | 7.46e-01 | 100.0% | 67.3% |
| 3652359 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.97 | 94.0 | 7.37e-01 | 100.0% | 55.9% |
| 3610015 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.96 | 93.0 | 7.41e-01 | 100.0% | 63.0% |
| 3634044 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.96 | 93.0 | 7.04e-01 | 100.0% | 64.2% |
| 3625174 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.96 | 92.0 | 6.79e-01 | 100.0% | 65.7% |
| 3708939 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 86.0 | 7.04e-01 | 100.0% | 57.4% |
| 3508111 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 91.0 | 7.04e-01 | 100.0% | 71.7% |
| 3789604 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.94 | 92.0 | 7.54e-01 | 100.0% | 68.0% |
| 3600354 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.94 | 85.0 | 7.09e-01 | 100.0% | 59.3% |
| 3630114 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.92 | 88.0 | 7.39e-01 | 100.0% | 70.3% |
| 4452951 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.92 | 87.0 | 6.88e-01 | 100.0% | 65.7% |
| 3768919 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.92 | 88.0 | 5.90e-01 | 100.0% | 41.3% |
| 4238706 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.92 | 87.0 | 5.86e-01 | 100.0% | 40.0% |
| 223696 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.91 | 88.0 | 7.24e-01 | 100.0% | 66.2% |
| 2443871 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.91 | 86.0 | 6.94e-01 | 100.0% | 68.1% |
| 4878008 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.90 | 80.0 | 7.21e-01 | 100.0% | 71.9% |
| 3935542 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.90 | 86.0 | 7.16e-01 | 100.0% | 62.7% |
| 4887991 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.90 | 79.0 | 7.54e-01 | 100.0% | 81.3% |
| 3220667 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.90 | 85.0 | 7.38e-01 | 100.0% | 73.3% |
| 4830953 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.90 | 85.0 | 6.73e-01 | 100.0% | 58.4% |
| 3267708 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.89 | 85.0 | 7.15e-01 | 100.0% | 66.2% |
| 3096549 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.89 | 85.0 | 6.80e-01 | 100.0% | 67.5% |
| 3833806 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.89 | 83.0 | 7.03e-01 | 98.9% | 64.8% |
| 3935023 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.81 | 37.0 | 3.11e-01 | 92.6% | 27.3% |
| 4299749 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.79 | 74.0 | 6.30e-01 | 100.0% | 65.5% |
| 5083298 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.79 | 74.0 | 6.21e-01 | 100.0% | 62.7% |
| 4003767 | 603.1.1.136 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HB_ELP1 | 0.79 | 41.0 | 3.24e-01 | 100.0% | 28.2% |
| 1297277 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.79 | 74.0 | 5.81e-01 | 100.0% | 51.9% |
| 4373100 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.79 | 74.0 | 6.27e-01 | 100.0% | 64.8% |
| 4043618 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.79 | 73.0 | 6.14e-01 | 100.0% | 62.0% |
| 3959880 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.78 | 69.0 | 7.11e-01 | 98.9% | 98.9% |
| 5062336 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.78 | 73.0 | 5.94e-01 | 100.0% | 81.8% |
| 3343253 | 109.26.1.6 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_NUP160_120_M | 0.78 | 39.0 | 2.90e-01 | 97.9% | 20.0% |
| 4996069 | 604.10.1.0 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac | 0.76 | 45.0 | 4.63e-01 | 98.9% | 62.2% |
| 4175767 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.74 | 45.0 | 4.32e-01 | 100.0% | 54.3% |
| 5070237 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.68 | 38.0 | 3.91e-01 | 100.0% | 56.7% |
| 3462175 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 41.0 | 3.71e-01 | 100.0% | 44.6% |
| 3616195 | 603.1.1.148 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Keratin_assoc | 0.66 | 38.0 | 3.76e-01 | 100.0% | 52.4% |
| 3864552 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 40.0 | 3.92e-01 | 98.9% | 56.0% |
| 4170246 | 173.1.1.1 ↗ | alpha arrays › Uteroglobin-like › Uteroglobin-like › Uteroglobin-like › Uteroglobin | 0.65 | 51.0 | 5.51e-01 | 100.0% | 100.0% |
| 4935516 | 5051.1.1.1 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SNF | 0.64 | 57.0 | 3.61e-01 | 100.0% | 64.0% |
| 3909538 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 37.0 | 3.63e-01 | 100.0% | 52.9% |
| 3218640 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 44.0 | 3.95e-01 | 100.0% | 53.1% |
| 3898385 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 38.0 | 3.27e-01 | 100.0% | 38.7% |
| 5014572 | 2.21.1.3 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 | 0.61 | 49.0 | 4.07e-01 | 86.2% | 53.3% |
| 3753252 | 173.1.1.1 ↗ | alpha arrays › Uteroglobin-like › Uteroglobin-like › Uteroglobin-like › Uteroglobin | 0.60 | 43.0 | 4.63e-01 | 93.6% | 93.3% |
| 4029241 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.59 | 44.0 | 3.83e-01 | 76.6% | 52.9% |
| 3504303 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 40.0 | 3.93e-01 | 98.9% | 67.0% |
| 3188337 | 192.2.1.6 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_3 | 0.57 | 51.0 | 4.66e-01 | 100.0% | 84.0% |
| 4154382 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.57 | 51.0 | 4.18e-01 | 100.0% | 80.9% |
| 2895133 | 173.1.1.0 ↗ | alpha arrays › Uteroglobin-like › Uteroglobin-like › Uteroglobin-like | 0.56 | 39.0 | 4.13e-01 | 93.6% | 82.1% |
| 4548049 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.54 | 43.0 | 3.87e-01 | 85.1% | 68.5% |
| 5046473 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.54 | 45.0 | 4.63e-01 | 100.0% | 93.3% |
| 3266118 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.53 | 41.0 | 3.74e-01 | 100.0% | 62.4% |
| 3598088 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.52 | 36.0 | 3.28e-01 | 75.5% | 51.5% |
| 3434008 | 3860.1.1.168 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › DUF668 | 0.52 | 42.0 | 3.75e-01 | 90.4% | 62.1% |
| 4335847 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.52 | 47.0 | 3.77e-01 | 96.8% | 74.7% |
| 5079962 | 601.28.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › DUF4129 | 0.51 | 40.0 | 3.87e-01 | 86.2% | 100.0% |
| 3840293 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.51 | 36.0 | 3.28e-01 | 74.5% | 55.4% |
| 3971908 | 601.13.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS | 0.50 | 46.0 | 4.15e-01 | 97.9% | 76.0% |
D5
medium
residues 565-599
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1bozA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.59 | 44.0 | 2.99e-01 | 100.0% | 35.5% |
D6
medium
residues 686-832_1007-1032_1146-1172
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 206.4 | 1.00e-60 | 95.0% | 35.3% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1bjtA05 | 3.90.199.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 | 0.95 | 89.0 | 8.06e-01 | 95.0% | 96.4% |
| 2xcqA02 | 3.90.199.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 | 0.86 | 80.0 | 7.06e-01 | 95.5% | 96.7% |
| 1zarA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.73 | 33.0 | 4.85e-01 | 81.5% | 95.5% |
| 4gyiA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.71 | 33.0 | 4.79e-01 | 81.5% | 94.6% |
| 2co5A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.70 | 34.0 | 4.83e-01 | 83.0% | 98.9% |
| 3r0aA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.70 | 34.0 | 4.38e-01 | 77.5% | 78.3% |
| 2od5A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 29.0 | 4.26e-01 | 96.5% | 98.9% |
| 3x1oA00 | 1.20.120.1790 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.56 | 39.0 | 4.41e-01 | 90.0% | 94.6% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4887989 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.93 | 64.0 | 6.95e-01 | 73.5% | 81.0% |
| 3768919 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.89 | 83.0 | 6.97e-01 | 94.5% | 99.7% |
| 4238706 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.88 | 86.0 | 7.16e-01 | 99.5% | 100.0% |
| 4865162 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.83 | 53.0 | 6.60e-01 | 77.5% | 98.5% |
| 5030817 | 101.1.2.54 ↗ | alpha arrays › HTH › HTH › winged helix domain › Penicillinase_R | 0.78 | 34.0 | 4.25e-01 | 92.5% | 63.8% |
| 5073138 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.76 | 35.0 | 4.62e-01 | 79.5% | 76.5% |
| 4997662 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.75 | 33.0 | 4.41e-01 | 77.0% | 74.5% |
| 3383404 | 101.1.2.154 ↗ | alpha arrays › HTH › HTH › winged helix domain › CDT1_C | 0.74 | 36.0 | 4.94e-01 | 71.0% | 90.4% |
| 3499387 | 101.1.2.154 ↗ | alpha arrays › HTH › HTH › winged helix domain › CDT1_C | 0.72 | 37.0 | 4.89e-01 | 72.0% | 89.1% |
| 3613894 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.71 | 38.0 | 3.47e-01 | 70.0% | 38.9% |
| 3841412 | 101.1.2.154 ↗ | alpha arrays › HTH › HTH › winged helix domain › CDT1_C | 0.71 | 36.0 | 4.71e-01 | 71.5% | 85.2% |
| 3272289 | 101.1.2.53 ↗ | alpha arrays › HTH › HTH › winged helix domain › Mnd1 | 0.70 | 32.0 | 3.85e-01 | 95.5% | 62.1% |
| 3715972 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.70 | 37.0 | 3.52e-01 | 70.5% | 43.9% |
| 2417725 | 101.1.2.467 ↗ | alpha arrays › HTH › HTH › winged helix domain › WHD_Rok | 0.68 | 29.0 | 3.95e-01 | 86.5% | 75.7% |
| 5046890 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.67 | 37.0 | 4.37e-01 | 74.5% | 75.7% |
| 3282607 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 33.0 | 4.04e-01 | 85.5% | 74.4% |
| 5021067 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 34.0 | 4.67e-01 | 81.5% | 97.1% |
| 4997248 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 32.0 | 4.33e-01 | 70.5% | 91.0% |
| 4947850 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 34.0 | 4.63e-01 | 79.5% | 97.1% |
| 4971686 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.63 | 32.0 | 4.34e-01 | 83.0% | 92.4% |
| 4008626 | 101.1.2.297 ↗ | alpha arrays › HTH › HTH › winged helix domain › Mrr_N | 0.62 | 37.0 | 4.45e-01 | 99.0% | 87.4% |
| 3274420 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.61 | 38.0 | 4.59e-01 | 82.5% | 93.1% |
| 3891495 | 108.1.1.29 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_7 | 0.58 | 30.0 | 4.04e-01 | 93.5% | 95.2% |
| 3733040 | 101.1.2.22 ↗ | alpha arrays › HTH › HTH › winged helix domain › PCI | 0.57 | 26.0 | 3.68e-01 | 94.5% | 92.2% |
| 3624335 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 36.0 | 3.82e-01 | 97.0% | 71.4% |
| 4040656 | 101.8.1.2 ↗ | alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 | 0.55 | 28.0 | 2.92e-01 | 78.0% | 50.6% |
| 3234666 | 101.1.2.577 ↗ | alpha arrays › HTH › HTH › winged helix domain › SPK | 0.54 | 29.0 | 3.60e-01 | 98.0% | 84.2% |
| 3225058 | 101.1.2.566 ↗ | alpha arrays › HTH › HTH › winged helix domain › CDT1, CDT1_C | 0.52 | 36.0 | 3.06e-01 | 75.5% | 43.1% |
| 3333385 | 108.1.1.73 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5+EF-hand_7 | 0.52 | 25.0 | 3.40e-01 | 74.5% | 87.6% |
| 3220456 | 101.1.1.264 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › SPK | 0.52 | 27.0 | 3.26e-01 | 94.0% | 74.6% |
| 3224387 | 101.1.7.2 ↗ | alpha arrays › HTH › HTH › Methylated DNA-protein cysteine methyltransferase-C › SPK | 0.51 | 27.0 | 3.41e-01 | 98.5% | 83.3% |
D7
medium
residues 894-984
Domain cluster:
rep: DNA_topoisomerase_II__YP_009173327__Chrysochromulina_ericina_virus__455364__D878-969
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 42.0 | 8.10e-11 | 100.0% | 20.0% |