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IMGVR_UViG_3300007812_000019-3300007812-Ga0105109_100035011

Arc-Vir

IMGVR_UViG_3300007812_000019-3300007812-Ga0105109_100035011

Quality

74.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 129-188
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.72 48.0 4.20e-01 71.7% 46.2%
4hzuS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.72 57.0 4.19e-01 88.3% 32.9%
1ukfA00 3.90.70.20 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.70 50.0 3.54e-01 76.7% 25.5%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 50.0 3.91e-01 75.0% 46.7%
1lkoA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 51.0 3.86e-01 80.0% 35.2%
3ermB00 1.10.10.710 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like 0.69 49.0 4.84e-01 76.7% 76.6%
2x4hA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 49.0 3.86e-01 76.7% 72.9%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 48.0 4.16e-01 75.0% 50.0%
2f93B00 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 48.0 5.14e-01 88.3% 90.2%
2r40D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.68 57.0 3.87e-01 98.3% 30.0%
1q5nA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.67 43.0 3.94e-01 75.0% 48.1%
2ntxA01 1.20.58.2010 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 0.66 48.0 3.28e-01 76.7% 24.3%
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.66 49.0 5.05e-01 81.7% 91.2%
4nooB00 1.10.8.1160 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.66 53.0 4.64e-01 91.7% 78.9%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.66 51.0 4.81e-01 86.7% 97.3%
3qqaA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 55.0 4.25e-01 98.3% 41.8%
1n5uA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.64 44.0 3.70e-01 73.3% 41.7%
1dd3A01 1.20.5.710 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Single helix bin 0.64 42.0 4.38e-01 88.3% 71.9%
1z6oM00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 48.0 3.38e-01 81.7% 28.3%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 48.0 4.35e-01 83.3% 76.5%
2pusA05 1.10.1740.80 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.62 40.0 3.67e-01 75.0% 48.8%
3teqB00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 46.0 3.95e-01 81.7% 80.2%
3b0cW00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.62 47.0 4.49e-01 86.7% 95.9%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 46.0 4.62e-01 81.7% 80.6%
7dfeA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.61 44.0 3.44e-01 78.3% 36.2%
2jdiG01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.60 47.0 4.74e-01 88.3% 83.6%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 45.0 4.31e-01 81.7% 69.0%
3e0sA00 1.40.20.10 Mainly Alpha › Alpha solenoid › CHAD domain › CHAD domain 0.60 50.0 3.20e-01 93.3% 34.8%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 43.0 3.86e-01 85.0% 54.1%
3q2eA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.59 43.0 3.61e-01 78.3% 62.6%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.58 48.0 4.14e-01 90.0% 70.0%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 41.0 3.66e-01 75.0% 64.7%
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.54 37.0 3.54e-01 75.0% 100.0%
2lm4A01 1.10.150.250 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Flavinator of succinate dehydrogenase 0.54 37.0 3.28e-01 73.3% 53.3%
1nrwA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.51 41.0 3.23e-01 90.0% 41.5%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3341345 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.79 69.0 5.39e-01 100.0% 90.8%
3839762 1008.1.1.0 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain 0.74 52.0 4.59e-01 73.3% 52.9%
4983398 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.73 56.0 3.90e-01 81.7% 84.2%
3278617 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.73 51.0 5.50e-01 75.0% 92.0%
3598304 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.72 59.0 4.10e-01 95.0% 93.0%
3518379 3502.1.1.1 alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG 0.71 51.0 5.32e-01 76.7% 89.1%
4952080 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.71 60.0 4.24e-01 100.0% 95.6%
4967576 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.70 61.0 4.63e-01 100.0% 73.1%
4831662 5043.1.1.1 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › Htr2 0.69 52.0 5.08e-01 81.7% 75.8%
3335926 7023.1.1.2 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › Pex2_Pex12 0.69 57.0 4.72e-01 93.3% 63.6%
4955683 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.68 55.0 3.67e-01 91.7% 74.4%
4990037 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.67 52.0 3.69e-01 88.3% 27.5%
3958572 5067.1.1.4 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL 0.67 56.0 4.33e-01 96.7% 53.6%
4958350 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.67 54.0 3.81e-01 93.3% 67.6%
3901129 605.1.1.111 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › TMEM72 0.66 48.0 4.37e-01 76.7% 61.3%
4983608 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.66 53.0 5.20e-01 90.0% 84.6%
3514275 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.66 50.0 4.31e-01 81.7% 53.7%
5028384 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.66 54.0 3.57e-01 93.3% 74.6%
5040031 632.22.1.199 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PLDc_N 0.66 53.0 4.81e-01 91.7% 90.6%
3973864 6026.1.1.2 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › GlpM 0.65 53.0 4.47e-01 95.0% 67.9%
4957365 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.65 55.0 4.60e-01 98.3% 76.4%
4972776 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.65 52.0 3.49e-01 95.0% 71.6%
4221177 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 45.0 4.82e-01 75.0% 100.0%
3932415 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.64 52.0 3.41e-01 95.0% 20.0%
185221 3502.1.1.1 alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG 0.64 46.0 4.55e-01 80.0% 76.1%
3242033 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.63 47.0 4.14e-01 85.0% 52.0%
3989094 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 45.0 4.35e-01 81.7% 65.7%
3560750 192.17.1.0 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.63 43.0 4.14e-01 71.7% 64.3%
3336677 605.1.1.132 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF641 0.63 42.0 3.98e-01 70.0% 58.7%
3505857 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.62 51.0 3.95e-01 95.0% 96.6%
4674 192.7.1.1 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › FemAB 0.62 46.0 4.55e-01 81.7% 76.9%
3749766 7023.1.1.2 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › Pex2_Pex12 0.61 51.0 4.34e-01 100.0% 70.9%
3729994 3755.3.1.284 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Utp11 0.61 47.0 3.65e-01 83.3% 39.2%
3864752 376.1.1.113 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › Pex2_Pex12 0.61 51.0 4.36e-01 100.0% 74.3%
3412881 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.61 46.0 4.33e-01 88.3% 88.7%
3386800 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.60 44.0 4.44e-01 81.7% 83.3%
4982050 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.58 40.0 3.92e-01 75.0% 84.3%
2474880 397.7.1.0 few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 0.58 42.0 4.48e-01 90.0% 100.0%
3799142 192.17.1.0 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.58 39.0 3.81e-01 71.7% 98.6%
3461932 3922.1.1.189 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF630 0.56 45.0 3.87e-01 88.3% 67.4%
4150867 5058.1.1.29 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › AlaE 0.55 41.0 3.67e-01 88.3% 53.7%
D2 medium residues 4-125
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.74 63.0 5.47e-01 91.8% 65.8%
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 44.0 4.08e-01 91.0% 52.2%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 40.0 4.06e-01 89.3% 62.5%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.60 41.0 4.64e-01 77.9% 93.4%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.60 48.0 4.99e-01 91.0% 90.4%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 45.0 4.66e-01 93.4% 83.2%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.59 44.0 4.43e-01 88.5% 76.0%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.59 45.0 4.73e-01 87.7% 86.7%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 42.0 4.57e-01 79.5% 88.1%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.58 48.0 4.89e-01 94.3% 91.5%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.57 47.0 4.58e-01 88.5% 80.3%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.57 44.0 4.29e-01 84.4% 75.2%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 46.0 4.55e-01 88.5% 86.9%
4cbeA00 1.20.120.1640 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 42.0 3.52e-01 91.0% 45.9%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.55 46.0 4.27e-01 89.3% 88.5%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 46.0 4.49e-01 91.0% 85.8%
2om6A02 1.10.150.400 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.55 29.0 3.51e-01 96.7% 78.5%
3rkoG00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 39.0 4.29e-01 77.9% 92.0%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.54 46.0 4.34e-01 91.0% 88.3%
3k66A01 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.54 49.0 4.13e-01 100.0% 96.7%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.54 42.0 3.65e-01 83.6% 65.3%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 40.0 3.24e-01 77.0% 42.1%
1w9cA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.54 45.0 3.39e-01 93.4% 45.2%
3fhnA04 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.53 43.0 4.27e-01 92.6% 82.4%
4mndA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.53 44.0 3.80e-01 91.0% 57.1%
2oezA02 1.10.3900.10 Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like 0.53 39.0 3.63e-01 79.5% 94.5%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.52 40.0 3.95e-01 88.5% 75.8%
1oedA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.52 40.0 4.03e-01 84.4% 86.6%
2hxoA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 34.0 3.29e-01 90.2% 57.6%
6axfA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.51 36.0 3.68e-01 100.0% 75.2%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.51 42.0 3.96e-01 88.5% 73.5%
5tpmB00 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.50 38.0 3.68e-01 82.0% 94.3%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3385721 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.68 59.0 5.12e-01 94.3% 65.9%
3585493 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.66 52.0 4.97e-01 82.8% 74.3%
3714252 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 46.0 3.50e-01 70.5% 49.8%
4982918 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.66 55.0 4.74e-01 91.0% 58.0%
3961355 5050.1.1.14 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › ATG22 0.66 56.0 5.42e-01 94.3% 83.7%
3972329 633.5.1.0 alpha bundles › Bromodomain-like › LemA-like › LemA-like 0.64 39.0 3.57e-01 85.2% 44.8%
5038580 633.21.1.1 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 0.63 37.0 4.00e-01 88.5% 66.7%
3272925 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 52.0 5.22e-01 88.5% 92.0%
3600562 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 46.0 4.07e-01 81.1% 54.7%
3500075 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.61 50.0 5.08e-01 87.7% 93.3%
3782377 4177.1.1.9 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Snx8_BAR_dom 0.61 43.0 3.27e-01 72.1% 84.9%
3255241 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.58 49.0 5.01e-01 90.2% 94.8%
3179608 1075.5.1.5 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Rft-1 0.58 51.0 4.03e-01 97.5% 61.5%
4283454 604.8.1.2 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Mitofilin 0.58 46.0 3.75e-01 86.9% 89.2%
3325799 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.58 48.0 4.84e-01 94.3% 89.6%
4124285 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.57 50.0 4.75e-01 95.1% 82.1%
3995987 192.29.1.31 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CRIC_ras_sig 0.57 48.0 4.55e-01 91.0% 79.3%
3211053 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.57 49.0 4.51e-01 92.6% 83.9%
5010597 5058.1.1.99 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › DUF373 0.57 43.0 4.14e-01 79.5% 81.4%
5020665 1075.5.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.56 49.0 3.85e-01 97.5% 52.0%
3472795 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.56 49.0 4.84e-01 95.1% 91.5%
3304001 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.56 46.0 4.46e-01 91.0% 84.3%
3559126 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 41.0 3.70e-01 89.3% 56.4%
3821849 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 50.0 3.82e-01 96.7% 74.3%
3621830 109.4.1.1706 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GoLoco, TPR_7, TPR_8, TPR_12 0.55 48.0 3.20e-01 95.9% 72.1%
4955278 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.55 42.0 4.23e-01 80.3% 92.0%
4987854 109.3.1.487 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF5667 0.55 47.0 4.54e-01 100.0% 82.1%
3619004 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.54 44.0 4.51e-01 87.7% 91.7%
4535108 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.54 46.0 4.46e-01 94.3% 87.9%
4078098 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.53 48.0 3.74e-01 100.0% 48.5%
4610519 603.1.1.211 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31236 0.53 48.0 3.96e-01 100.0% 64.5%
4487059 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.53 42.0 4.17e-01 85.2% 82.3%
3360519 3860.1.1.0 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm 0.53 47.0 3.61e-01 100.0% 51.2%
3451722 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.53 45.0 4.54e-01 91.8% 95.2%
4972788 601.2.1.0 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes 0.52 40.0 4.19e-01 91.0% 89.1%
3821959 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 48.0 4.59e-01 100.0% 87.9%
4663621 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.52 41.0 4.05e-01 82.8% 89.2%
3970945 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.51 41.0 4.20e-01 87.7% 87.8%
3395623 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.50 42.0 4.21e-01 95.9% 87.2%