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IMGVR_UViG_3300007985_000017-3300007985-Ga0100381_100027569

Arc-Vir

IMGVR_UViG_3300007985_000017-3300007985-Ga0100381_100027569

Quality

95.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 212-299
PDB
Domain cluster: representative
CATH (90)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8gccA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.93 84.0 8.57e-01 95.5% 100.0%
3qx3B03 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.91 87.0 8.24e-01 100.0% 91.0%
3l4jA04 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.86 81.0 7.66e-01 100.0% 91.2%
3lpxB02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.81 73.0 7.18e-01 97.7% 96.8%
3eeeA00 3.90.1520.10 Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain 0.72 54.0 4.22e-01 80.7% 43.1%
1itpA00 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.70 48.0 5.06e-01 79.5% 80.5%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 50.0 5.23e-01 80.7% 82.7%
3tf8B00 3.90.1520.10 Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain 0.68 50.0 3.92e-01 76.1% 42.4%
2pa8D01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.68 51.0 5.12e-01 84.1% 78.4%
4bpuC00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.68 54.0 3.58e-01 86.4% 33.5%
4limA00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.68 54.0 3.53e-01 86.4% 29.9%
6gmhK00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.67 53.0 4.86e-01 85.2% 65.2%
2m9kA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.67 49.0 4.85e-01 83.0% 73.1%
2kwaA00 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.67 56.0 5.35e-01 92.0% 94.1%
3va7A05 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.67 55.0 5.31e-01 89.8% 87.0%
4pcqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.66 47.0 4.84e-01 78.4% 78.6%
3ezjA02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.65 46.0 5.12e-01 81.8% 97.1%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.65 48.0 4.57e-01 78.4% 75.5%
4qjvB00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.65 53.0 5.22e-01 88.6% 84.0%
1i6uA01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.65 47.0 5.27e-01 84.1% 97.1%
3zxoA00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.65 45.0 4.01e-01 71.6% 90.4%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.65 49.0 4.82e-01 80.7% 74.0%
2kkhA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 46.0 4.91e-01 80.7% 88.0%
4p6qA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 48.0 5.02e-01 78.4% 89.7%
3dfeA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 45.0 4.67e-01 81.8% 79.3%
6i3gA02 3.90.76.10 Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 0.64 51.0 4.69e-01 87.5% 78.8%
4binA01 2.60.40.3500 Mainly Beta › Sandwich › Immunoglobulin-like › 0.64 51.0 4.66e-01 86.4% 75.0%
2cdqA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.64 52.0 5.29e-01 90.9% 92.9%
5w2fA01 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.64 51.0 5.18e-01 88.6% 88.4%
4ctaA02 3.30.70.2860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 45.0 4.80e-01 78.4% 86.7%
2ebbA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.63 51.0 5.01e-01 88.6% 84.4%
1zpvA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 47.0 4.84e-01 80.7% 83.5%
1darA05 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 43.0 4.36e-01 79.5% 71.3%
2dt9A01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 48.0 5.09e-01 88.6% 97.3%
5mmjh01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.63 44.0 4.78e-01 73.9% 90.7%
4o1pD02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.63 50.0 3.68e-01 88.6% 53.6%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.62 51.0 4.12e-01 88.6% 56.3%
2x7gA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.62 43.0 4.36e-01 72.7% 77.3%
2j0wA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.62 49.0 5.02e-01 89.8% 93.8%
3i4pA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.62 44.0 4.53e-01 78.4% 78.6%
1usmA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.62 49.0 5.18e-01 86.4% 100.0%
4uskA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.62 47.0 3.88e-01 80.7% 84.4%
3p96A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.62 46.0 4.69e-01 79.5% 84.5%
5mmiU01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 46.0 4.71e-01 79.5% 93.9%
2qmaA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.61 50.0 4.51e-01 90.9% 65.6%
3znuA00 3.30.70.1060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel 0.61 45.0 4.48e-01 79.5% 80.9%
1dcoA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.61 49.0 4.75e-01 88.6% 82.8%
1stzA03 3.30.390.60 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Heat-inducible transcription repressor hrca homolog; domain 3 0.61 36.0 3.68e-01 93.2% 58.4%
3c1mA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.60 49.0 4.08e-01 90.9% 96.3%
2a2cA02 3.30.70.3170 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 45.0 4.59e-01 79.5% 86.9%
1q5yC00 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.60 43.0 4.49e-01 78.4% 81.7%
2x7iA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.60 45.0 4.04e-01 80.7% 93.0%
1gmeA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 44.0 3.70e-01 77.3% 75.3%
4v1al00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.60 52.0 4.61e-01 98.9% 69.9%
4g6tA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.60 48.0 4.32e-01 89.8% 68.8%
2oi2A02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.60 44.0 3.89e-01 78.4% 93.3%
5o5cB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.60 48.0 4.33e-01 89.8% 63.3%
6liuC02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.59 48.0 4.48e-01 90.9% 75.9%
2plgA01 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.59 47.0 4.13e-01 86.4% 72.0%
5i2cB01 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.59 47.0 4.02e-01 87.5% 93.2%
2clqA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.59 42.0 4.25e-01 73.9% 77.6%
8gz3B01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.58 46.0 4.54e-01 87.5% 94.6%
5g4iB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 47.0 3.97e-01 92.0% 53.1%
1jyaB00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.57 46.0 4.21e-01 90.9% 74.4%
4g1vA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.57 45.0 4.10e-01 85.2% 89.8%
3douA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 40.0 3.19e-01 71.6% 38.3%
3bc8A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.56 46.0 4.05e-01 92.0% 79.0%
2gpjA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.56 44.0 4.27e-01 85.2% 92.0%
1krhA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.56 44.0 4.28e-01 86.4% 89.7%
3kxyJ00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.56 45.0 4.07e-01 92.0% 71.3%
2r6hA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.55 43.0 3.73e-01 85.2% 93.7%
3oksA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 48.0 3.84e-01 96.6% 90.9%
7ylrA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.55 42.0 4.07e-01 85.2% 95.2%
3lwsF02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 44.0 4.21e-01 89.8% 79.8%
1i94H01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.55 43.0 4.53e-01 84.1% 100.0%
4hqeA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 41.0 3.93e-01 80.7% 70.5%
2awnC03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 30.0 3.52e-01 84.1% 79.3%
1kyzA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 40.0 3.85e-01 79.5% 72.8%
2eixA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.54 41.0 3.97e-01 85.2% 85.8%
5tr9A01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.54 42.0 4.16e-01 87.5% 89.6%
5gt8D02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.54 40.0 3.62e-01 79.5% 100.0%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.54 43.0 4.29e-01 92.0% 84.0%
5ylyA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.53 42.0 3.95e-01 87.5% 86.6%
1q9uA00 3.30.310.70 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TT1751-like domain 0.53 42.0 3.81e-01 88.6% 96.9%
2lmcB00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.53 31.0 3.55e-01 86.4% 82.0%
5hs7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.78e-01 77.3% 69.4%
1yyvB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 41.0 3.80e-01 83.0% 68.8%
4dcmA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 36.0 2.89e-01 72.7% 88.6%
1ub9A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 38.0 3.67e-01 79.5% 73.0%
6qpqB00 1.10.10.580 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E 0.51 39.0 4.04e-01 81.8% 91.4%
ECOD (94)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3277529 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 89.0 7.04e-01 100.0% 56.2%
3998667 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 88.0 6.55e-01 100.0% 50.8%
3594650 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.91 85.0 6.80e-01 100.0% 54.4%
2390536 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.91 82.0 6.47e-01 94.3% 53.1%
3614277 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 84.0 6.46e-01 100.0% 48.3%
3719735 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 85.0 6.72e-01 100.0% 54.5%
3789606 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.88 83.0 6.48e-01 100.0% 55.9%
3220665 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.88 82.0 6.39e-01 100.0% 56.6%
4887990 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 82.0 6.52e-01 100.0% 55.9%
4878007 101.1.2.9 alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.87 78.0 6.52e-01 95.5% 62.0%
3096551 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.86 81.0 6.15e-01 100.0% 53.0%
4946212 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.82 75.0 5.81e-01 100.0% 60.0%
4266765 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.81 75.0 6.01e-01 100.0% 57.0%
5052421 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.70 57.0 5.63e-01 93.2% 83.2%
4450775 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.69 57.0 5.46e-01 90.9% 84.6%
3290652 306.2.1.0 a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor 0.69 57.0 5.72e-01 89.8% 87.8%
3315331 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.69 56.0 5.89e-01 89.8% 97.5%
4645570 304.102.1.2 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruD 0.68 55.0 4.27e-01 88.6% 89.2%
4616161 304.8.1.47 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_ACR9_3rd 0.68 56.0 5.29e-01 89.8% 85.7%
3807910 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.68 56.0 5.90e-01 89.8% 98.8%
4138832 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.68 56.0 5.65e-01 89.8% 95.5%
3285929 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.68 58.0 5.78e-01 93.2% 96.7%
4398167 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.68 56.0 5.66e-01 89.8% 96.6%
3367362 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.68 57.0 5.95e-01 90.9% 100.0%
4545902 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.68 55.0 5.52e-01 88.6% 93.3%
3462522 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.68 56.0 5.03e-01 92.0% 83.2%
3318862 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.67 55.0 5.58e-01 90.9% 91.8%
4342449 305.1.1.1 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L 0.67 56.0 5.03e-01 89.8% 80.8%
3308135 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 57.0 5.66e-01 92.0% 92.2%
4429744 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.67 55.0 5.42e-01 89.8% 91.6%
5029727 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.67 51.0 4.31e-01 81.8% 48.7%
3671608 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 55.0 5.18e-01 90.9% 79.1%
4205520 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 55.0 5.52e-01 90.9% 91.1%
4298844 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 55.0 5.36e-01 89.8% 86.3%
3364258 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.67 56.0 5.67e-01 92.0% 94.3%
4409327 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.67 55.0 5.24e-01 92.0% 83.8%
4500983 304.8.1.53 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › GlnD_5th 0.67 55.0 4.54e-01 90.9% 55.6%
3802901 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 53.0 5.65e-01 87.5% 100.0%
3675774 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.67 55.0 5.64e-01 90.9% 97.6%
3438815 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.67 55.0 5.61e-01 90.9% 95.3%
3592576 305.1.1.0 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase 0.66 55.0 4.86e-01 89.8% 64.8%
3283785 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.66 56.0 5.59e-01 90.9% 93.3%
3840480 327.11.2.39 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_PARP14_3 0.66 48.0 5.12e-01 80.7% 89.3%
4292806 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 55.0 5.20e-01 92.0% 84.8%
3341034 304.8.1.57 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_ACR_D1 0.66 55.0 5.16e-01 92.0% 80.9%
4248471 304.8.1.57 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_ACR_D1 0.66 54.0 5.42e-01 90.9% 97.8%
3739949 306.6.1.0 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like 0.66 53.0 5.38e-01 87.5% 97.6%
4515771 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.66 54.0 5.25e-01 92.0% 92.0%
3661475 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 55.0 4.56e-01 93.2% 56.4%
3452017 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 54.0 5.66e-01 90.9% 100.0%
3386922 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 55.0 5.75e-01 89.8% 100.0%
3368757 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.66 56.0 5.48e-01 94.3% 100.0%
3824912 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.66 54.0 5.66e-01 92.0% 100.0%
4885937 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.66 54.0 5.37e-01 90.9% 96.7%
4505080 242.1.1.2 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 0.66 49.0 4.38e-01 79.5% 68.8%
3367441 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 54.0 5.29e-01 93.2% 89.9%
3831627 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 53.0 5.56e-01 90.9% 98.8%
3171307 306.3.1.1 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.65 55.0 5.08e-01 94.3% 71.3%
3451456 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 55.0 5.44e-01 93.2% 96.8%
3688090 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.65 54.0 5.43e-01 90.9% 93.3%
4936622 305.1.1.1 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L 0.65 51.0 5.04e-01 86.4% 78.9%
3165990 310.3.1.22 a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related › PF27480, PF30181 0.65 47.0 4.31e-01 76.1% 98.3%
3382396 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 54.0 5.55e-01 90.9% 97.6%
4234924 304.8.1.57 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_ACR_D1 0.65 53.0 5.10e-01 89.8% 87.0%
3818197 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 51.0 5.41e-01 85.2% 100.0%
5041064 305.2.1.1 a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.65 52.0 5.12e-01 87.5% 86.3%
3445077 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 53.0 5.46e-01 90.9% 98.8%
4951755 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.65 51.0 5.23e-01 88.6% 89.4%
3298082 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.65 53.0 5.24e-01 90.9% 87.1%
3719440 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.64 54.0 4.78e-01 90.9% 65.6%
4119008 305.2.1.1 a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.64 51.0 5.04e-01 86.4% 82.1%
5026235 304.165.1.5 a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 › HVO_A0563_N 0.64 54.0 4.59e-01 92.0% 60.0%
3645785 304.8.1.57 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_ACR_D1 0.64 53.0 5.04e-01 92.0% 78.1%
4665602 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 52.0 5.14e-01 90.9% 88.4%
3276287 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.64 50.0 4.78e-01 85.2% 71.4%
4501630 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 46.0 4.80e-01 81.8% 85.0%
3953697 305.2.1.1 a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.63 51.0 5.06e-01 88.6% 85.3%
3285931 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 52.0 4.77e-01 90.9% 73.0%
4996908 304.8.1.4 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.62 46.0 4.62e-01 79.5% 77.3%
4097357 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.62 53.0 3.93e-01 98.9% 87.8%
4062288 304.41.1.1 a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.62 46.0 3.85e-01 81.8% 46.0%
4028358 305.2.1.1 a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.62 48.0 4.85e-01 85.2% 90.0%
5010510 304.8.1.21 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.62 44.0 4.63e-01 80.7% 85.0%
4092984 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.61 52.0 3.88e-01 100.0% 86.3%
4926825 304.4.1.2 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MIase 0.61 45.0 4.28e-01 79.5% 74.3%
3477161 5104.1.1.3 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2 0.61 52.0 4.45e-01 98.9% 90.7%
3486967 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.61 52.0 4.44e-01 98.9% 90.7%
4297454 306.3.1.2 a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › Img2 0.60 52.0 4.53e-01 97.7% 75.4%
1018784 241.1.1.3 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › CesT 0.60 48.0 4.32e-01 89.8% 68.8%
3489258 306.8.1.0 a+b two layers › Glucose permease domain IIB-like › TM1457-like › TM1457-like 0.59 49.0 4.66e-01 92.0% 98.1%
5013605 304.165.1.0 a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 0.58 51.0 4.37e-01 97.7% 69.7%
3184022 1.1.7.7 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.57 45.0 4.01e-01 87.5% 92.3%
3596774 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.56 42.0 3.85e-01 80.7% 99.2%
4934355 7523.1.1.23 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › PBP_like_2 0.51 38.0 3.10e-01 81.8% 78.3%
D2 high residues 338-447
PDB
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8gccA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.88 69.0 7.15e-01 81.8% 90.4%
1bgwA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.87 70.0 7.04e-01 83.6% 98.2%
3qx3A04 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.86 68.0 7.15e-01 81.8% 98.0%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.86 44.0 4.96e-01 86.4% 65.1%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.79 41.0 4.09e-01 85.5% 49.6%
1zvuA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.76 70.0 6.42e-01 100.0% 79.3%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.75 45.0 4.68e-01 87.3% 65.7%
4z4qA04 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.71 55.0 6.07e-01 82.7% 100.0%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.70 31.0 3.34e-01 85.5% 47.9%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 42.0 5.33e-01 82.7% 100.0%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.68 39.0 3.57e-01 89.1% 42.7%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.67 35.0 3.81e-01 86.4% 60.0%
3cqcB01 1.20.58.1380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 34.0 3.76e-01 86.4% 60.0%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 33.0 3.59e-01 87.3% 56.5%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 48.0 5.03e-01 89.1% 82.5%
4issA02 1.20.58.1700 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 41.0 4.72e-01 84.5% 94.7%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.61 52.0 4.30e-01 90.0% 81.3%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 46.0 3.51e-01 86.4% 38.9%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.58 47.0 4.52e-01 87.3% 94.4%
3w6zA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.58 43.0 4.22e-01 83.6% 71.1%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 35.0 3.53e-01 88.2% 60.0%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.55 40.0 3.72e-01 73.6% 76.7%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 46.0 3.59e-01 86.4% 45.1%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.52 41.0 3.82e-01 97.3% 65.7%
2yevB01 1.10.287.90 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 28.0 3.08e-01 71.8% 62.4%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 45.0 3.89e-01 90.0% 89.3%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 43.0 3.80e-01 86.4% 64.5%
6g94A00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.52 41.0 3.56e-01 85.5% 97.7%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 43.0 3.73e-01 89.1% 62.1%
8d8lN01 1.10.287.1480 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 30.0 3.29e-01 86.4% 72.1%
3o39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 32.0 3.42e-01 84.5% 72.9%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3267708 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.94 90.0 8.01e-01 100.0% 79.3%
3630114 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 86.0 7.71e-01 100.0% 83.4%
3600354 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.90 84.0 7.41e-01 100.0% 72.0%
3708939 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 84.0 7.30e-01 100.0% 69.7%
4878008 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.89 78.0 7.55e-01 95.5% 83.5%
4887991 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.89 79.0 8.01e-01 98.2% 95.3%
3508111 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.88 84.0 6.94e-01 100.0% 83.9%
3789604 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.88 84.0 7.42e-01 100.0% 80.7%
3328306 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.88 83.0 6.75e-01 100.0% 75.3%
3276180 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.88 83.0 6.68e-01 100.0% 77.4%
3768919 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 83.0 5.82e-01 100.0% 48.7%
4452951 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 83.0 6.90e-01 100.0% 76.6%
3652359 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 83.0 6.97e-01 100.0% 68.8%
4238706 101.1.2.9 alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.86 82.0 5.74e-01 100.0% 47.2%
3605285 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.86 42.0 3.80e-01 86.4% 37.2%
3718739 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.86 81.0 6.96e-01 100.0% 79.4%
3610015 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.86 81.0 6.91e-01 100.0% 77.0%
3634044 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.85 80.0 6.52e-01 100.0% 74.2%
2443871 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.85 80.0 6.83e-01 100.0% 79.5%
3462175 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.84 44.0 4.09e-01 86.4% 43.8%
3625174 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.84 79.0 6.24e-01 100.0% 75.2%
3220667 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.84 79.0 7.27e-01 100.0% 87.4%
3465978 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.83 45.0 4.00e-01 94.5% 40.7%
3935542 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.83 78.0 6.93e-01 100.0% 76.0%
5083298 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.81 76.0 6.73e-01 100.0% 76.0%
3596738 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.78 45.0 4.06e-01 86.4% 44.8%
3254719 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.76 39.0 4.27e-01 87.3% 58.9%
3573589 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.76 48.0 5.01e-01 92.7% 70.0%
3890044 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.75 44.0 5.67e-01 83.6% 95.6%
3723852 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 38.0 3.60e-01 86.4% 42.2%
4683248 5086.1.1.66 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR 0.71 39.0 3.61e-01 85.5% 42.1%
3563679 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 42.0 4.32e-01 82.7% 61.9%
3810014 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.70 55.0 5.18e-01 86.4% 69.8%
3508301 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.69 45.0 3.79e-01 90.9% 41.7%
3688960 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.69 41.0 3.37e-01 95.5% 32.2%
5018554 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 45.0 4.72e-01 91.8% 73.0%
3671258 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.67 46.0 4.29e-01 86.4% 58.5%
5011995 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.62 48.0 5.10e-01 80.9% 100.0%
3718462 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.60 43.0 4.61e-01 94.5% 86.3%
3397986 3755.4.1.1 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.59 46.0 3.81e-01 87.3% 48.9%
3640652 5054.1.1.12 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › NCA2 0.58 49.0 3.98e-01 87.3% 52.1%
3720652 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.57 40.0 3.05e-01 89.1% 31.4%
3255250 109.24.1.1 alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › DHR-2_Lobe_A 0.57 42.0 3.71e-01 83.6% 53.1%
4168471 4207.1.1.1 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Med21 0.56 45.0 4.04e-01 88.2% 60.6%
3488631 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.56 41.0 3.06e-01 90.0% 30.5%
3946576 5086.1.1.66 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR 0.56 34.0 3.15e-01 91.8% 47.4%
3472438 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 47.0 2.89e-01 86.4% 18.1%
3983048 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 47.0 3.04e-01 86.4% 24.6%
3187793 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 47.0 3.69e-01 88.2% 47.1%
3498458 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 46.0 3.93e-01 86.4% 84.2%
3715936 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 47.0 3.93e-01 89.1% 59.4%
3763261 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 46.0 3.55e-01 87.3% 44.5%
3275580 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.54 45.0 4.02e-01 89.1% 64.8%
3235839 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.53 48.0 4.02e-01 93.6% 82.9%
1291200 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.52 46.0 3.33e-01 94.5% 70.3%
3576467 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.52 46.0 3.29e-01 95.5% 65.2%
3255232 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.51 43.0 3.21e-01 89.1% 46.4%
4500042 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.50 41.0 2.70e-01 88.2% 24.0%
D3 medium residues 33-151
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 83.9 1.60e-23 100.0% 27.6%
D4 medium residues 152-211_302-337
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 43.0 4.20e-11 75.0% 13.9%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bjtA05 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.89 77.0 5.47e-01 99.0% 34.5%
2yfvC00 6.10.250.2010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.76 28.0 3.48e-01 90.6% 53.3%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3998667 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 87.0 6.61e-01 100.0% 99.0%
3277529 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 65.0 5.27e-01 74.0% 100.0%
3719735 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.88 68.0 5.47e-01 79.2% 100.0%
3789606 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.88 65.0 5.19e-01 76.0% 98.2%
2390536 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 54.0 4.34e-01 78.1% 37.0%
3188905 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 67.0 5.23e-01 79.2% 100.0%
3220665 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.86 65.0 5.10e-01 77.1% 98.3%
3614277 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.85 67.0 5.30e-01 82.3% 93.9%
3594650 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.85 61.0 4.99e-01 74.0% 100.0%
4266765 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.81 59.0 4.78e-01 75.0% 97.6%
4624017 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.80 57.0 4.53e-01 74.0% 97.8%
3965475 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.79 58.0 4.41e-01 76.0% 99.0%
3962339 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.79 57.0 4.42e-01 74.0% 99.5%
4946212 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.78 58.0 4.52e-01 76.0% 100.0%
396210 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.78 57.0 4.10e-01 75.0% 77.1%
3590557 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.77 59.0 4.57e-01 80.2% 93.8%
3567761 377.9.1.8 few secondary structure elements › Glucocorticoid receptor-like › HIT/MYND zinc finger-like › HIT/MYND zinc finger-like › zf-FCS 0.76 24.0 3.76e-01 71.9% 67.5%
4024263 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.76 59.0 4.42e-01 81.2% 98.6%
3696633 3393.1.1.2 extended segments › CAA3-type cytochrome c oxidase subunit IV › CAA3-type cytochrome c oxidase subunit IV › CAA3-type cytochrome c oxidase subunit IV › Kinesin_assoc 0.53 34.0 3.43e-01 100.0% 65.3%
5057974 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.52 39.0 3.68e-01 100.0% 65.2%