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IMGVR_UViG_3300008001_000257-3300008001-Ga0100389_10231604
Arc-VirIMGVR_UViG_3300008001_000257-3300008001-Ga0100389_10231604
Identity
- Kingdom:
- archaea
Quality
79.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-56
Domain cluster:
representative
CATH (52)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1a8rA01 | 1.10.286.10 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › GTP cyclohydrolase I, N-terminal domain | 0.83 | 59.0 | 4.93e-01 | 75.0% | 51.8% |
| 1ukfA00 | 3.90.70.20 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › | 0.82 | 74.0 | 4.97e-01 | 100.0% | 39.9% |
| 3anwA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 55.0 | 4.21e-01 | 73.1% | 51.3% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.78 | 55.0 | 3.55e-01 | 73.1% | 19.1% |
| 1sg7A00 | 1.10.1740.70 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB | 0.78 | 69.0 | 6.12e-01 | 100.0% | 74.7% |
| 3ktcA00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.76 | 53.0 | 3.21e-01 | 88.5% | 11.5% |
| 2ogiB00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.75 | 61.0 | 4.16e-01 | 92.3% | 26.4% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.75 | 56.0 | 3.91e-01 | 78.8% | 53.2% |
| 1t6jA03 | 1.10.274.20 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 | 0.75 | 65.0 | 5.26e-01 | 100.0% | 59.2% |
| 2qgsB01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.74 | 64.0 | 5.37e-01 | 96.2% | 62.5% |
| 4k22B01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.74 | 66.0 | 4.21e-01 | 100.0% | 86.1% |
| 1ls1A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.74 | 67.0 | 5.54e-01 | 100.0% | 61.8% |
| 4bkxA01 | 4.10.1240.50 | Few Secondary Structures › Irregular › Hormone receptor fold › | 0.73 | 54.0 | 4.17e-01 | 78.8% | 38.1% |
| 1ufhA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.73 | 51.0 | 3.72e-01 | 76.9% | 31.0% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.73 | 57.0 | 3.90e-01 | 84.6% | 28.4% |
| 4x5mA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.72 | 52.0 | 4.34e-01 | 76.9% | 55.8% |
| 3craB01 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.72 | 51.0 | 4.26e-01 | 75.0% | 53.5% |
| 2no4A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.70 | 60.0 | 5.32e-01 | 96.2% | 84.0% |
| 2csxA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.69 | 48.0 | 3.37e-01 | 73.1% | 38.0% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.69 | 49.0 | 4.19e-01 | 75.0% | 63.9% |
| 2z15A00 | 3.90.640.90 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › Anti-proliferative protein, N-terminal domain | 0.68 | 60.0 | 4.61e-01 | 100.0% | 58.0% |
| 1iuqA01 | 1.10.1200.50 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal | 0.67 | 58.0 | 5.15e-01 | 98.1% | 76.3% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 48.0 | 3.79e-01 | 76.9% | 43.4% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.67 | 49.0 | 3.53e-01 | 82.7% | 25.5% |
| 2f93B00 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 48.0 | 4.87e-01 | 76.9% | 88.2% |
| 1o9gA02 | 1.10.287.540 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 44.0 | 4.81e-01 | 71.2% | 83.7% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.66 | 48.0 | 3.30e-01 | 76.9% | 24.9% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.66 | 48.0 | 4.39e-01 | 76.9% | 62.7% |
| 3u4qA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 48.0 | 3.16e-01 | 78.8% | 18.4% |
| 1v4gA01 | 6.10.140.800 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 45.0 | 4.16e-01 | 80.8% | 55.1% |
| 3ermB00 | 1.10.10.710 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like | 0.65 | 46.0 | 4.41e-01 | 76.9% | 64.1% |
| 1ldjA02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.65 | 48.0 | 3.71e-01 | 80.8% | 38.2% |
| 3nufB00 | 1.10.1790.10 | Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › PRD domain | 0.65 | 57.0 | 4.46e-01 | 100.0% | 92.0% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.64 | 53.0 | 3.94e-01 | 88.5% | 49.6% |
| 3fblA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 56.0 | 4.83e-01 | 100.0% | 67.1% |
| 4i2aA01 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.63 | 52.0 | 4.29e-01 | 92.3% | 81.9% |
| 3knwB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 53.0 | 3.75e-01 | 98.1% | 65.0% |
| 4k7bA00 | 1.20.120.1740 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sodium ion translocating NADH-quinone reductase subunit C-like | 0.62 | 52.0 | 4.07e-01 | 96.2% | 44.1% |
| 8cdaC01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.61 | 48.0 | 3.76e-01 | 88.5% | 90.6% |
| 3pfyA02 | 6.10.20.180 | Special › Helix non-globular › Arc Repressor Mutant, subunit A › | 0.61 | 53.0 | 5.17e-01 | 100.0% | 96.5% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 53.0 | 3.67e-01 | 100.0% | 57.1% |
| 3ltoA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.60 | 49.0 | 3.61e-01 | 90.4% | 34.3% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 51.0 | 4.52e-01 | 94.2% | 65.3% |
| 2oo2A00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.60 | 51.0 | 4.53e-01 | 94.2% | 65.8% |
| 4al0A00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.59 | 51.0 | 3.78e-01 | 100.0% | 87.7% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.59 | 50.0 | 3.79e-01 | 92.3% | 75.4% |
| 2pmrA00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.58 | 50.0 | 4.43e-01 | 96.2% | 72.4% |
| 2ahmG01 | 6.10.250.2820 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.57 | 47.0 | 3.79e-01 | 96.2% | 47.5% |
| 1gs0A01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.57 | 46.0 | 3.56e-01 | 92.3% | 41.9% |
| 1u2zA01 | 1.10.260.170 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › | 0.56 | 43.0 | 3.07e-01 | 98.1% | 24.7% |
| 6he1B01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.52 | 44.0 | 4.16e-01 | 96.2% | 87.5% |
| 4ar9A02 | 1.10.390.20 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › | 0.51 | 39.0 | 2.93e-01 | 86.5% | 69.0% |
ECOD (65)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5006643 | 2006.1.4.2 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN | 0.90 | 61.0 | 4.31e-01 | 73.1% | 25.5% |
| 3603511 | 2004.1.1.194 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2 | 0.85 | 63.0 | 3.99e-01 | 86.5% | 17.4% |
| 4026018 | 6026.1.1.1 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 | 0.84 | 60.0 | 4.62e-01 | 76.9% | 34.8% |
| 4221177 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.82 | 61.0 | 6.27e-01 | 78.8% | 92.0% |
| 3456717 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.82 | 54.0 | 5.03e-01 | 73.1% | 55.4% |
| 3962155 | 191.1.1.49 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_13_2 | 0.81 | 60.0 | 5.07e-01 | 78.8% | 50.6% |
| 3518379 | 3502.1.1.1 ↗ | alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG | 0.79 | 58.0 | 5.77e-01 | 78.8% | 81.8% |
| 3239689 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.79 | 55.0 | 4.27e-01 | 73.1% | 51.4% |
| 2075033 | 3787.1.1.0 ↗ | alpha bundles › HAD superfamily helical bundle insertion domain | 0.78 | 71.0 | 6.11e-01 | 100.0% | 69.6% |
| 3575 | 4084.1.1.1 ↗ | alpha bundles › ChaB-like › ChaB-like › ChaB-like › ChaB | 0.78 | 69.0 | 6.12e-01 | 100.0% | 74.7% |
| 3264733 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.78 | 56.0 | 4.47e-01 | 75.0% | 56.8% |
| 4626413 | 601.1.1.102 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PigN | 0.77 | 58.0 | 3.95e-01 | 80.8% | 24.4% |
| 3507421 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.77 | 53.0 | 4.79e-01 | 73.1% | 77.1% |
| 3601017 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.76 | 53.0 | 4.47e-01 | 73.1% | 63.5% |
| 4999592 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.76 | 66.0 | 5.81e-01 | 96.2% | 82.7% |
| 3202941 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.76 | 53.0 | 4.03e-01 | 73.1% | 46.1% |
| 3990438 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.75 | 54.0 | 4.25e-01 | 76.9% | 37.3% |
| 3906344 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.75 | 53.0 | 4.33e-01 | 73.1% | 62.2% |
| 4024241 | 4979.2.1.1 ↗ | alpha arrays › C-terminal domain of Hypothetical protein MPN330-like › XRN2-binding domain (XTBD) › XRN2-binding domain (XTBD) › XTBD | 0.75 | 65.0 | 5.69e-01 | 98.1% | 64.1% |
| 4241417 | 219.1.1.21 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C58 | 0.75 | 67.0 | 4.30e-01 | 100.0% | 34.9% |
| 3972074 | 3236.2.1.2 ↗ | alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › AbrB | 0.75 | 63.0 | 3.85e-01 | 96.2% | 46.2% |
| 3435740 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.75 | 55.0 | 4.33e-01 | 78.8% | 45.5% |
| 3690615 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.75 | 52.0 | 3.82e-01 | 73.1% | 40.0% |
| 3706387 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.75 | 52.0 | 4.08e-01 | 73.1% | 50.5% |
| 4939237 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.74 | 64.0 | 5.94e-01 | 96.2% | 81.5% |
| 3243786 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.74 | 51.0 | 3.81e-01 | 73.1% | 42.4% |
| 4982330 | 3355.1.1.41 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF401 | 0.74 | 52.0 | 3.06e-01 | 75.0% | 10.1% |
| 3630756 | 5043.1.1.2 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › SPC12 | 0.73 | 55.0 | 5.04e-01 | 82.7% | 80.0% |
| 3926812 | 397.7.1.0 ↗ | few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 | 0.73 | 66.0 | 5.93e-01 | 98.1% | 80.0% |
| 3742905 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.73 | 50.0 | 4.19e-01 | 73.1% | 61.1% |
| 3447846 | 5010.1.1.6 ↗ | extended segments › Bacterial aa3 type cytochrome c oxidase subunit IV › Bacterial aa3 type cytochrome c oxidase subunit IV › Bacterial aa3 type cytochrome c oxidase subunit IV › SPC12 | 0.72 | 53.0 | 5.44e-01 | 78.8% | 87.5% |
| 5040031 | 632.22.1.199 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PLDc_N | 0.72 | 62.0 | 5.25e-01 | 96.2% | 80.0% |
| 3962191 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.72 | 64.0 | 5.37e-01 | 100.0% | 84.4% |
| 4955309 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.72 | 51.0 | 4.39e-01 | 75.0% | 88.7% |
| 4328717 | 604.5.1.41 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PigN | 0.72 | 55.0 | 3.83e-01 | 82.7% | 25.7% |
| 3673805 | 148.1.3.285 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Cyclin_C | 0.71 | 62.0 | 5.27e-01 | 98.1% | 67.1% |
| 3688139 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.71 | 49.0 | 3.71e-01 | 73.1% | 42.4% |
| 3741742 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.71 | 64.0 | 4.00e-01 | 100.0% | 39.6% |
| 4021030 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.71 | 56.0 | 3.81e-01 | 82.7% | 24.3% |
| 2072258 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.71 | 51.0 | 4.05e-01 | 76.9% | 38.7% |
| 4089749 | 601.18.1.25 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PigN | 0.71 | 55.0 | 3.79e-01 | 82.7% | 25.0% |
| 3591320 | 5043.1.1.2 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › SPC12 | 0.71 | 57.0 | 5.15e-01 | 86.5% | 85.7% |
| 3742906 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.70 | 49.0 | 3.70e-01 | 75.0% | 43.2% |
| 1411677 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.69 | 49.0 | 4.19e-01 | 75.0% | 63.9% |
| 3709879 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.69 | 58.0 | 5.21e-01 | 98.1% | 81.3% |
| 5027220 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.69 | 50.0 | 4.80e-01 | 78.8% | 68.3% |
| 3631283 | 5069.1.1.82 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PigN | 0.69 | 57.0 | 3.85e-01 | 92.3% | 56.4% |
| 3183479 | 3758.1.1.47 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › PigN | 0.68 | 53.0 | 3.71e-01 | 82.7% | 26.5% |
| 3282145 | 618.2.1.1 ↗ | a+b complex topology › DNA mimic protein DMP12-like › Immunity protein CdiI › Immunity protein CdiI › DUF6247 | 0.67 | 54.0 | 5.31e-01 | 94.2% | 83.6% |
| 3726873 | 601.1.2.108 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PigN | 0.67 | 56.0 | 3.83e-01 | 92.3% | 58.9% |
| 3633090 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.67 | 54.0 | 3.49e-01 | 88.5% | 45.0% |
| 1388524 | 243.17.1.1 ↗ | a+b two layers › Cystatin-like › C-terminal domain of PatG › C-terminal domain of PatG › PatG_C | 0.67 | 57.0 | 4.36e-01 | 100.0% | 48.5% |
| 3659606 | 3361.1.1.5 ↗ | alpha bundles › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › PF28983 | 0.66 | 56.0 | 4.33e-01 | 94.2% | 71.3% |
| 3998578 | 142.1.1.41 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › RabGAP-TBC | 0.65 | 53.0 | 5.07e-01 | 100.0% | 92.3% |
| 3924657 | 540.1.1.1 ↗ | few secondary structure elements › Cytochrome c oxidase subunit h › Cytochrome c oxidase subunit h › Cytochrome c oxidase subunit h › COX6B | 0.65 | 51.0 | 4.58e-01 | 82.7% | 61.4% |
| 3876144 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.64 | 53.0 | 4.44e-01 | 100.0% | 70.0% |
| 4591251 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.62 | 53.0 | 4.42e-01 | 92.3% | 61.2% |
| 3960067 | 191.1.1.49 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_13_2 | 0.61 | 55.0 | 4.97e-01 | 100.0% | 81.4% |
| 4023166 | 7076.1.1.0 ↗ | 0.61 | 53.0 | 4.91e-01 | 96.2% | 78.5% | |
| 3760771 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.60 | 52.0 | 4.48e-01 | 100.0% | 75.3% |
| 3599328 | 616.1.1.6 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Mpo1-like | 0.60 | 53.0 | 4.42e-01 | 98.1% | 58.9% |
| 3638401 | 4095.1.1.1 ↗ | alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_N | 0.59 | 48.0 | 3.57e-01 | 96.2% | 36.8% |
| 4942003 | 1101.1.1.0 ↗ | alpha bundles › Uncharacterized protein LPG2271 › Uncharacterized protein LPG2271 › Uncharacterized protein LPG2271 | 0.58 | 52.0 | 4.33e-01 | 100.0% | 84.4% |
| 3908723 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.54 | 46.0 | 3.89e-01 | 96.2% | 81.1% |
| 4991730 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.53 | 39.0 | 3.75e-01 | 100.0% | 70.8% |
D2
high
residues 62-252
Domain cluster:
rep: IMGVR_UViG_3300020814_000341-3300020814-Ga0214088_182449110__D102-238
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1o6eA00 | 3.20.16.10 | Alpha Beta › Alpha-Beta Barrel › Serine Protease, Human Cytomegalovirus Protease; Chain A › Herpesvirus/Caudovirus protease domain | 0.60 | 45.0 | 4.27e-01 | 77.5% | 87.1% |
| 1at3A00 | 3.20.16.10 | Alpha Beta › Alpha-Beta Barrel › Serine Protease, Human Cytomegalovirus Protease; Chain A › Herpesvirus/Caudovirus protease domain | 0.58 | 43.0 | 4.17e-01 | 75.9% | 86.6% |
| 2k3yA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.54 | 29.0 | 3.57e-01 | 91.6% | 82.6% |
| 5ds1A00 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 22.0 | 3.02e-01 | 78.5% | 71.7% |
| 2f8xC03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 27.0 | 3.59e-01 | 80.1% | 92.6% |
| 3pmiA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.53 | 19.0 | 3.03e-01 | 92.1% | 87.7% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5083920 | 50.1.1.0 ↗ | beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin | 0.93 | 65.0 | 7.66e-01 | 71.2% | 98.6% |
| 3945940 | 50.1.1.3 ↗ | beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S78 | 0.82 | 61.0 | 7.04e-01 | 83.8% | 100.0% |
| 5083161 | 50.1.1.3 ↗ | beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S78 | 0.80 | 60.0 | 6.88e-01 | 79.6% | 100.0% |
| 4995675 | 50.1.1.0 ↗ | beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin | 0.74 | 61.0 | 6.57e-01 | 84.8% | 100.0% |
| 3585229 | 50.1.1.2 ↗ | beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S77 | 0.74 | 51.0 | 5.89e-01 | 71.7% | 95.0% |
| 4981188 | 1.1.15.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › PK beta-barrel domain-like | 0.56 | 26.0 | 3.60e-01 | 86.9% | 92.9% |
| 4974398 | 11.1.1.51 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LEA_2 | 0.53 | 34.0 | 3.92e-01 | 80.1% | 92.3% |
| 3432327 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.52 | 35.0 | 4.08e-01 | 83.2% | 100.0% |
| 4928967 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.51 | 36.0 | 4.08e-01 | 80.6% | 97.1% |
| 3883341 | 2.1.1.15 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon | 0.50 | 30.0 | 3.44e-01 | 94.2% | 80.7% |
D3
medium
residues 325-413
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1u61A00 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.75 | 52.0 | 4.58e-01 | 71.9% | 96.9% |
| 4zqeA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.74 | 52.0 | 5.12e-01 | 73.0% | 86.5% |
| 4cxfA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.74 | 56.0 | 5.65e-01 | 79.8% | 85.1% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.72 | 49.0 | 5.08e-01 | 70.8% | 84.7% |
| 4zpxA02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.72 | 53.0 | 5.26e-01 | 77.5% | 81.5% |
| 1or7B01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.68 | 50.0 | 4.98e-01 | 77.5% | 76.6% |
| 7krzA02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.67 | 50.0 | 5.16e-01 | 78.7% | 84.5% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.67 | 46.0 | 4.70e-01 | 71.9% | 85.2% |
| 2o7gA00 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.66 | 47.0 | 4.81e-01 | 76.4% | 79.5% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.65 | 48.0 | 4.89e-01 | 77.5% | 96.6% |
| 1h3lB00 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.64 | 47.0 | 4.92e-01 | 76.4% | 92.3% |
| 5jazA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.64 | 45.0 | 4.49e-01 | 73.0% | 83.5% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.64 | 45.0 | 4.71e-01 | 74.2% | 100.0% |
| 2z3tA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.61 | 48.0 | 3.16e-01 | 85.4% | 64.2% |
| 3gwlA00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.61 | 41.0 | 3.91e-01 | 76.4% | 58.5% |
| 2i7aA00 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.59 | 41.0 | 3.44e-01 | 71.9% | 41.4% |
| 6fakA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.58 | 44.0 | 4.54e-01 | 80.9% | 91.4% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.58 | 40.0 | 3.63e-01 | 73.0% | 86.0% |
| 5oklA01 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.57 | 41.0 | 3.99e-01 | 77.5% | 73.3% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 41.0 | 4.36e-01 | 76.4% | 97.5% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 38.0 | 3.96e-01 | 75.3% | 86.9% |
| 1kxpD01 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.52 | 38.0 | 3.86e-01 | 77.5% | 87.2% |
| 5dqqA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 41.0 | 3.61e-01 | 85.4% | 64.4% |
| 2vk9A04 | 1.10.274.80 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › | 0.51 | 36.0 | 3.44e-01 | 74.2% | 64.4% |
| 2icwG02 | 1.10.10.530 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › mam-mhc complex, Chain D, Domain 2 | 0.50 | 37.0 | 3.74e-01 | 77.5% | 83.1% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3563012 | 142.1.1.22 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › SCAF11-like_C | 0.79 | 58.0 | 6.13e-01 | 77.5% | 92.5% |
| 3499902 | 181.1.1.12 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SCAF11-like_C | 0.76 | 56.0 | 6.11e-01 | 77.5% | 98.6% |
| 3669993 | 142.1.1.22 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › SCAF11-like_C | 0.73 | 54.0 | 5.58e-01 | 78.7% | 100.0% |
| 3491856 | 142.1.1.22 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › SCAF11-like_C | 0.72 | 53.0 | 5.24e-01 | 78.7% | 77.9% |
| 4209656 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.69 | 52.0 | 4.99e-01 | 82.0% | 75.2% |
| 3576883 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 37.0 | 3.60e-01 | 92.1% | 47.0% |
| 3973703 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.66 | 52.0 | 5.23e-01 | 84.3% | 86.7% |
| 5066642 | 4009.1.1.1 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom | 0.66 | 45.0 | 4.94e-01 | 70.8% | 90.0% |
| 3182610 | 327.11.2.85 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › GDH2_N | 0.66 | 46.0 | 5.17e-01 | 74.2% | 100.0% |
| 3728039 | 632.7.1.28 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › Yae1_N | 0.65 | 51.0 | 4.81e-01 | 82.0% | 81.9% |
| 3620069 | 633.1.1.0 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain | 0.64 | 51.0 | 4.82e-01 | 85.4% | 72.4% |
| 3657184 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.63 | 47.0 | 4.42e-01 | 78.7% | 70.9% |
| 4949396 | 606.1.1.0 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain | 0.62 | 44.0 | 4.46e-01 | 74.2% | 74.4% |
| 3497423 | 109.4.1.1373 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Syndetin_C, Vps54_N | 0.62 | 47.0 | 2.80e-01 | 79.8% | 19.6% |
| 3257901 | 103.1.1.57 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › GDH2_N | 0.62 | 43.0 | 4.72e-01 | 75.3% | 92.9% |
| 5035838 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.59 | 44.0 | 4.46e-01 | 78.7% | 95.6% |
| 4034270 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.59 | 43.0 | 4.46e-01 | 76.4% | 100.0% |
| 3286103 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.57 | 40.0 | 4.24e-01 | 74.2% | 95.0% |
| 3736265 | 109.4.1.862 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ZW10_C2 | 0.57 | 50.0 | 2.96e-01 | 93.3% | 14.0% |
| 3865887 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.55 | 38.0 | 3.94e-01 | 71.9% | 95.3% |
| 3939780 | 109.4.1.1373 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Syndetin_C, Vps54_N | 0.54 | 46.0 | 2.81e-01 | 100.0% | 48.6% |
| 3900656 | 3831.1.1.6 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › POF1B_HlH | 0.53 | 37.0 | 3.83e-01 | 73.0% | 100.0% |
| 4976283 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.53 | 37.0 | 3.42e-01 | 73.0% | 57.4% |
| 5023625 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.52 | 37.0 | 3.55e-01 | 73.0% | 68.0% |