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IMGVR_UViG_3300009548_000051-3300009548-Ga0116107_10015058

Arc-Vir

IMGVR_UViG_3300009548_000051-3300009548-Ga0116107_10015058

Quality

70.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 76-125
PDB
Domain cluster: representative
CATH (69)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.80 72.0 4.88e-01 100.0% 45.5%
4pxdA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.79 70.0 5.35e-01 100.0% 98.3%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.77 68.0 5.71e-01 100.0% 89.4%
3m70A01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.75 54.0 4.25e-01 100.0% 36.8%
1u8sA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.75 66.0 5.51e-01 100.0% 89.5%
6s2wA01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.74 67.0 5.62e-01 100.0% 65.9%
3p96A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.74 62.0 5.37e-01 100.0% 92.9%
2mv2A00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.72 57.0 4.16e-01 100.0% 31.1%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.72 60.0 4.99e-01 100.0% 53.3%
7sqxA02 3.30.70.2150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 60.0 4.94e-01 100.0% 83.7%
1u8sA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.71 61.0 5.23e-01 100.0% 94.0%
4h4nA00 2.60.40.3750 Mainly Beta › Sandwich › Immunoglobulin-like › 0.71 58.0 5.40e-01 100.0% 72.6%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.70 58.0 4.86e-01 100.0% 52.1%
3w7bA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 58.0 4.99e-01 100.0% 94.3%
2vzwB00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.69 55.0 3.92e-01 88.0% 87.9%
2qlcA00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.69 59.0 4.44e-01 100.0% 40.5%
1zpvA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 58.0 4.96e-01 100.0% 91.8%
2pw9C03 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.68 52.0 3.89e-01 100.0% 31.9%
3h20A01 3.30.1490.240 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain 0.68 54.0 5.00e-01 100.0% 69.7%
4qwoB00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.68 52.0 3.88e-01 86.0% 87.9%
3n0vA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.67 56.0 4.82e-01 100.0% 95.2%
3eipA00 3.10.50.20 Alpha Beta › Roll › Chitinase A; domain 3 › Cloacin immunity protein 0.66 55.0 4.78e-01 100.0% 90.5%
2il5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.66 51.0 3.62e-01 86.0% 88.9%
7pjjA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.65 48.0 3.58e-01 100.0% 31.0%
1xc3A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 53.0 4.33e-01 100.0% 46.6%
3ll3B01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 56.0 3.64e-01 100.0% 28.6%
2gupA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 54.0 4.46e-01 100.0% 50.5%
2ipiA02 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.65 51.0 3.44e-01 100.0% 37.1%
4clcA00 3.30.450.150 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Haem-degrading domain 0.64 47.0 3.35e-01 82.0% 24.9%
2v0uA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.64 49.0 3.58e-01 86.0% 34.9%
2j1vA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.64 50.0 3.68e-01 100.0% 31.2%
3r7wB02 3.30.450.190 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.63 49.0 3.77e-01 86.0% 86.4%
3ifrA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.63 54.0 3.57e-01 100.0% 30.7%
1skoB00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.63 48.0 3.75e-01 84.0% 87.1%
2j3wC00 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.63 50.0 3.69e-01 88.0% 79.3%
5jtwA02 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.63 53.0 4.29e-01 100.0% 48.0%
1nrjA00 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.63 49.0 3.59e-01 88.0% 74.8%
2r6fA03 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.63 47.0 4.37e-01 100.0% 62.5%
4u7cB04 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.63 51.0 4.17e-01 100.0% 55.0%
1jx4A04 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.62 53.0 4.34e-01 100.0% 94.9%
1unnC00 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.62 51.0 4.12e-01 100.0% 45.0%
1wmhA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.62 44.0 3.86e-01 100.0% 48.2%
1wkbA02 3.90.740.10 Alpha Beta › Alpha-Beta Complex › Isoleucyl-tRNA Synthetase; domain 2 › Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 0.61 45.0 2.95e-01 80.0% 93.0%
2jxtA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.61 53.0 4.68e-01 100.0% 68.4%
2xqyA03 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.61 50.0 3.83e-01 100.0% 38.3%
7ct3A01 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.61 45.0 3.56e-01 84.0% 88.9%
5x6vF00 3.30.450.190 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.60 46.0 3.59e-01 86.0% 84.7%
3gzkA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 49.0 4.26e-01 98.0% 58.2%
2ox5B00 2.60.40.2470 Mainly Beta › Sandwich › Immunoglobulin-like › SoxY domain 0.60 47.0 3.73e-01 100.0% 40.9%
2hf6A00 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.59 47.0 3.43e-01 90.0% 66.4%
3fedA02 3.50.30.30 Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › 0.59 49.0 3.29e-01 98.0% 98.2%
5ck3C00 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.59 45.0 3.61e-01 86.0% 77.1%
6cc0A01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.58 45.0 3.20e-01 86.0% 82.3%
4dbrA02 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.58 47.0 3.04e-01 92.0% 48.6%
7yh1A01 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.57 42.0 3.34e-01 86.0% 36.0%
3hqiA01 2.60.210.10 Mainly Beta › Sandwich › Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A › Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 0.57 49.0 3.64e-01 100.0% 45.3%
3gm8A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 50.0 3.94e-01 100.0% 48.6%
2z5bA00 3.30.230.100 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.57 43.0 3.30e-01 86.0% 33.9%
2pn5A02 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.57 47.0 3.85e-01 100.0% 48.5%
1accA02 2.60.120.240 Mainly Beta › Sandwich › Jelly Rolls › Protective antigen, heptamerisation domain 0.57 48.0 3.28e-01 100.0% 40.8%
3b8fB00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.56 47.0 3.46e-01 100.0% 34.5%
5icuA00 2.60.40.1220 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 46.0 3.78e-01 100.0% 48.0%
1alo006 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.56 40.0 3.17e-01 82.0% 84.9%
3bgaA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 46.0 3.70e-01 100.0% 52.3%
6ztgA01 3.30.70.1070 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat 0.55 44.0 4.06e-01 100.0% 100.0%
3afgA03 2.60.120.380 Mainly Beta › Sandwich › Jelly Rolls › 0.55 47.0 3.79e-01 100.0% 64.7%
5xbfA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 46.0 3.94e-01 100.0% 72.4%
3r7wC02 3.30.450.190 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.52 48.0 3.65e-01 100.0% 60.7%
3isyA00 2.60.40.2360 Mainly Beta › Sandwich › Immunoglobulin-like › Intracellular proteinase inhibitor BsuPI 0.52 45.0 3.47e-01 100.0% 51.3%
ECOD (65)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4952123 3986.2.1.0 a+b two layers › GTP-binding protein lepA C-terminal domain-like › Antitoxin Dmd › Antitoxin Dmd 0.83 65.0 6.15e-01 100.0% 71.7%
5010477 331.2.1.0 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.83 74.0 5.78e-01 98.0% 98.0%
4950017 304.134.1.3 a+b two layers › Alpha-beta plaits › MJ1480-like › MJ1480-like › PF26798 0.83 78.0 6.32e-01 100.0% 95.3%
4948793 304.134.1.3 a+b two layers › Alpha-beta plaits › MJ1480-like › MJ1480-like › PF26798 0.82 76.0 6.39e-01 100.0% 100.0%
3980369 304.15.1.0 a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain 0.82 71.0 5.61e-01 98.0% 99.0%
5070107 304.56.1.0 a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like 0.78 70.0 6.23e-01 100.0% 98.6%
5010788 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.78 68.0 4.31e-01 96.0% 35.6%
3184485 76.1.1.0 beta duplicates or obligate multimers › beta-Prism I › beta-Prism I › beta-Prism I 0.73 59.0 4.64e-01 100.0% 42.6%
4958616 304.128.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB 0.72 62.0 5.47e-01 100.0% 97.3%
3923566 304.56.1.0 a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like 0.71 61.0 5.30e-01 100.0% 97.5%
3218185 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 58.0 3.91e-01 100.0% 28.8%
4977323 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.69 53.0 3.96e-01 86.0% 33.6%
4947741 821.1.1.17 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › PF27096 0.68 56.0 4.74e-01 92.0% 85.9%
4280109 2492.1.1.9 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › RadC 0.68 58.0 4.45e-01 100.0% 40.8%
5000280 5103.1.1.0 a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 0.68 61.0 4.80e-01 100.0% 62.0%
4231372 4.1.1.307 beta barrels › SH3 › SH3 › SH3 › PF26132 0.67 58.0 5.27e-01 100.0% 100.0%
5065878 2492.1.1.7 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › FdhD-NarQ 0.67 52.0 3.84e-01 100.0% 30.9%
4964967 102.2.1.3 alpha arrays › HhH/H2TH › H2TH › H2TH › NFACT_N 0.67 53.0 3.76e-01 86.0% 37.9%
3942062 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.66 50.0 3.59e-01 86.0% 27.3%
5046979 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.66 52.0 4.04e-01 86.0% 90.0%
3588352 304.44.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › PriA_C 0.66 55.0 4.61e-01 100.0% 94.7%
5020151 2492.1.1.7 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › FdhD-NarQ 0.66 51.0 3.88e-01 100.0% 34.1%
4105434 2492.1.1.7 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › FdhD-NarQ 0.65 51.0 3.74e-01 100.0% 29.9%
5039154 10.1.2.0 beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.65 51.0 4.27e-01 100.0% 48.9%
5024071 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.65 48.0 3.68e-01 80.0% 76.5%
5012895 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.65 55.0 5.38e-01 100.0% 89.1%
5003530 2492.1.1.7 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › FdhD-NarQ 0.64 50.0 3.76e-01 100.0% 32.9%
3313678 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.64 51.0 3.71e-01 88.0% 71.4%
3256878 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.64 51.0 3.67e-01 88.0% 69.0%
3974768 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.64 49.0 3.54e-01 88.0% 28.4%
5059051 2492.1.1.7 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › FdhD-NarQ 0.63 48.0 3.70e-01 100.0% 32.9%
5073712 5103.1.1.0 a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 0.63 55.0 4.25e-01 100.0% 58.3%
4010783 223.8.1.2 a+b three layers › Profilin-like › LapD periplasmic domain › LapD periplasmic domain › CHASE8 0.63 48.0 3.81e-01 86.0% 84.5%
3783719 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.63 48.0 3.65e-01 84.0% 94.2%
4945021 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.63 51.0 4.16e-01 100.0% 70.9%
4010374 223.1.1.156 a+b three layers › Profilin-like › sensor domains › sensor domains › GAPES3 0.62 47.0 3.63e-01 84.0% 83.3%
5055164 5103.1.1.0 a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 0.62 54.0 4.32e-01 100.0% 63.8%
3258907 223.2.1.1 a+b three layers › Profilin-like › profilin-like › profilin-like › Profilin 0.62 44.0 3.37e-01 88.0% 30.0%
3271015 223.2.1.3 a+b three layers › Profilin-like › profilin-like › profilin-like › Clat_adaptor_s 0.62 50.0 3.59e-01 90.0% 69.3%
4944923 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.62 48.0 3.63e-01 88.0% 77.7%
4029586 10.32.1.203 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Seipin 0.61 54.0 3.84e-01 100.0% 49.3%
3251796 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.61 46.0 3.42e-01 86.0% 36.6%
5070409 821.1.1.0 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease 0.61 50.0 4.35e-01 100.0% 56.8%
5041452 303.1.1.1 a+b four layers › Pyruvoyl-dependent histidine and arginine decarboxylases › Pyruvoyl-dependent histidine and arginine decarboxylases › Pyruvoyl-dependent histidine and arginine decarboxylases › PvlArgDC 0.61 50.0 3.73e-01 100.0% 34.0%
3216210 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.61 48.0 4.90e-01 100.0% 94.0%
4028834 223.2.1.7 a+b three layers › Profilin-like › profilin-like › profilin-like › SRP-alpha_N 0.61 48.0 3.66e-01 88.0% 81.7%
3915206 10.32.1.203 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Seipin 0.60 52.0 3.62e-01 100.0% 44.0%
3991219 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 47.0 3.67e-01 90.0% 80.9%
3493644 10.32.1.203 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Seipin 0.59 49.0 3.51e-01 100.0% 69.7%
5053230 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 40.0 3.18e-01 82.0% 30.8%
3593295 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 45.0 3.58e-01 88.0% 89.1%
4944328 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 45.0 3.36e-01 86.0% 33.8%
3493599 223.2.1.3 a+b three layers › Profilin-like › profilin-like › profilin-like › Clat_adaptor_s 0.57 43.0 3.11e-01 86.0% 33.5%
3577468 2492.1.1.1 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › dCMP_cyt_deam_1 0.57 47.0 3.31e-01 98.0% 45.6%
4979666 223.2.1.5 a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7 0.55 40.0 3.28e-01 86.0% 87.0%
3228434 2487.1.1.7 a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" › PA 0.55 44.0 3.06e-01 100.0% 97.2%
4946840 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.54 38.0 3.07e-01 82.0% 33.9%
3739712 223.2.1.10 a+b three layers › Profilin-like › profilin-like › profilin-like › Gtr1_RagA 0.54 50.0 3.61e-01 100.0% 57.7%
3740347 10.32.1.203 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Seipin 0.54 44.0 3.24e-01 100.0% 75.8%
3349683 64.5.1.0 beta meanders › WW domain-like › Connector region of RNA helicase HrpB › Connector region of RNA helicase HrpB 0.53 41.0 3.84e-01 82.0% 85.0%
3804439 2.1.1.23 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › POT1 0.52 41.0 3.00e-01 88.0% 85.3%
5079496 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.52 47.0 3.56e-01 100.0% 64.3%
5052370 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.52 47.0 3.60e-01 100.0% 64.5%
5048521 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.51 47.0 3.88e-01 100.0% 84.7%
3251755 223.2.1.3 a+b three layers › Profilin-like › profilin-like › profilin-like › Clat_adaptor_s 0.50 46.0 3.14e-01 100.0% 41.8%
D2 medium residues 167-231
PDB
Domain cluster: representative
CATH (70)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1mgtA01 3.30.160.70 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Methylated DNA-protein cysteine methyltransferase domain 0.75 56.0 5.00e-01 78.5% 59.1%
1kz7C02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.73 59.0 4.54e-01 89.2% 40.9%
2giaB00 2.30.31.40 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › 0.72 55.0 4.23e-01 81.5% 75.3%
4v19S00 3.30.420.80 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribosomal protein S11/S14 0.72 54.0 4.19e-01 81.5% 47.6%
2giaA00 2.30.31.40 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › 0.71 54.0 4.10e-01 81.5% 68.8%
3u12A00 2.30.29.180 Mainly Beta › Roll › PH-domain like › Ubiquitin carboxyl-terminal hydrolase 26/29/37, pleckstrin homology-like domain 0.69 50.0 4.25e-01 76.9% 75.0%
2nugB02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.68 48.0 4.66e-01 73.8% 70.4%
1u14A00 3.90.950.10 Alpha Beta › Alpha-Beta Complex › Maf protein › 0.67 50.0 3.69e-01 80.0% 71.6%
1di2A00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.67 46.0 4.58e-01 72.3% 71.0%
3tqmA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.67 55.0 4.96e-01 90.8% 95.6%
3holA03 2.40.128.240 Mainly Beta › Beta Barrel › Lipocalin › 0.67 46.0 4.16e-01 72.3% 52.8%
2it9A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.66 52.0 4.33e-01 100.0% 48.3%
3h1qA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 47.0 3.63e-01 75.4% 41.2%
1ah5A03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.65 49.0 4.56e-01 84.6% 80.2%
1okjB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.64 46.0 3.73e-01 75.4% 39.4%
2dmyA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.64 45.0 3.87e-01 72.3% 50.5%
2aehA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.64 48.0 4.04e-01 80.0% 48.6%
1nyeA00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.63 52.0 4.12e-01 93.8% 45.5%
1imuA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.63 56.0 4.79e-01 100.0% 90.7%
4wj7D00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.63 45.0 3.66e-01 75.4% 87.8%
2qm1B01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.63 46.0 3.60e-01 80.0% 40.8%
2rqlA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.62 53.0 4.76e-01 100.0% 94.7%
3ulbA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 46.0 4.24e-01 80.0% 65.1%
1vyfA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.61 47.0 3.73e-01 83.1% 84.4%
1z05A02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 43.0 3.35e-01 75.4% 38.3%
1whqA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.61 46.0 4.50e-01 80.0% 76.1%
3b5hA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 46.0 4.24e-01 80.0% 84.1%
2bs6A01 2.40.128.190 Mainly Beta › Beta Barrel › Lipocalin › 0.61 44.0 4.10e-01 78.5% 88.1%
3ecrB03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.60 44.0 3.85e-01 78.5% 72.5%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.60 50.0 4.02e-01 98.5% 47.1%
7r8iA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.60 46.0 3.31e-01 87.7% 28.6%
1ei5A01 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.59 47.0 3.03e-01 87.7% 18.4%
3htvA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.59 42.0 3.61e-01 76.9% 51.4%
7b1xA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 47.0 3.01e-01 86.2% 82.4%
4azpA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.59 46.0 3.68e-01 86.2% 88.1%
6fopA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.59 44.0 3.05e-01 81.5% 53.1%
3kksB00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.59 49.0 3.70e-01 90.8% 98.0%
3cm1A00 2.30.31.20 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Sporulation-specific cell division protein SsgB 0.58 45.0 3.66e-01 87.7% 63.2%
2nvnA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.58 48.0 3.99e-01 93.8% 65.8%
1e8oA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.58 42.0 4.05e-01 81.5% 67.6%
2pmaA01 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.58 41.0 3.41e-01 76.9% 62.0%
3mcpA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 43.0 3.67e-01 81.5% 52.7%
2ltrA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.56 45.0 3.93e-01 90.8% 60.0%
2dixA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.56 44.0 4.18e-01 86.2% 74.4%
2ap1A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.56 42.0 3.30e-01 80.0% 38.1%
1i99I02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.56 41.0 3.44e-01 78.5% 92.3%
5upiA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.56 42.0 3.00e-01 80.0% 61.2%
3qkgA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.56 44.0 3.44e-01 92.3% 83.5%
6j9eJ00 3.30.160.560 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.56 42.0 4.18e-01 80.0% 86.4%
1e2tA03 2.40.128.150 Mainly Beta › Beta Barrel › Lipocalin › Cysteine proteinases 0.55 41.0 3.42e-01 81.5% 70.1%
4cy8A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 47.0 3.19e-01 98.5% 76.3%
1gm5A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 40.0 3.58e-01 83.1% 76.5%
3htyA00 2.40.128.280 Mainly Beta › Beta Barrel › Lipocalin › 0.54 38.0 3.45e-01 75.4% 61.7%
2ar5A00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.54 40.0 3.39e-01 83.1% 87.2%
2cm4A00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 39.0 3.16e-01 81.5% 60.0%
7vljA01 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.53 36.0 3.24e-01 70.8% 97.8%
4eq3A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 41.0 3.54e-01 84.6% 85.2%
3ke6B01 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.53 44.0 3.16e-01 98.5% 77.4%
3hkzG00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 36.0 3.14e-01 73.8% 91.2%
3p0cA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.53 39.0 3.34e-01 81.5% 83.8%
5wceA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.53 39.0 3.14e-01 80.0% 47.3%
3wcyA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 36.0 3.36e-01 73.8% 81.4%
2xlpB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 45.0 2.84e-01 95.4% 24.1%
1fyhB02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 41.0 3.56e-01 87.7% 84.5%
6z9cA01 2.60.40.1470 Mainly Beta › Sandwich › Immunoglobulin-like › ApaG domain 0.52 42.0 3.51e-01 92.3% 84.4%
1u7bA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.51 42.0 2.90e-01 95.4% 63.3%
2qm4A01 2.170.210.10 Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › DNA double-strand break repair and VJ recombination XRCC4, N-terminal 0.51 43.0 3.40e-01 95.4% 62.9%
6j8yA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.51 42.0 2.90e-01 95.4% 65.4%
6w0pA02 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.51 44.0 2.69e-01 96.9% 28.1%
2eenA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.50 40.0 2.94e-01 87.7% 53.1%
ECOD (78)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4969523 7089.1.1.0 a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD 0.77 57.0 6.20e-01 81.5% 94.4%
185116 295.1.1.2 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › SsgA 0.71 47.0 3.62e-01 72.3% 32.1%
3951937 330.8.1.1 a+b two layers › dsRBD-like › Rv2632c-like › Rv2632c-like › Rv2632c-like 0.71 58.0 5.26e-01 90.8% 85.4%
3742185 2003.1.5.26 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_28 0.70 47.0 2.86e-01 89.2% 11.6%
3780194 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.69 50.0 3.33e-01 76.9% 23.7%
3619264 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.68 54.0 4.86e-01 86.2% 63.3%
3602236 284.1.3.3 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › DUF4346 0.68 49.0 4.33e-01 76.9% 53.7%
3894031 330.1.1.6 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Staufen_C 0.67 49.0 4.45e-01 80.0% 58.8%
4026008 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.67 55.0 5.06e-01 90.8% 70.6%
3670595 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.67 50.0 4.35e-01 78.5% 55.8%
3939156 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.67 50.0 3.58e-01 80.0% 29.2%
3911301 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.66 46.0 4.18e-01 72.3% 57.6%
4040354 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.66 46.0 4.38e-01 72.3% 68.0%
3520951 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.66 50.0 4.52e-01 81.5% 61.1%
4943695 2484.1.1.331 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_III 0.66 46.0 3.50e-01 73.8% 36.8%
4105268 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.66 44.0 3.45e-01 70.8% 37.9%
4368826 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.65 46.0 3.47e-01 73.8% 36.9%
3710891 330.1.1.22 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › PF26536 0.65 53.0 4.56e-01 87.7% 100.0%
3392597 220.1.1.66 beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH 0.65 52.0 4.07e-01 89.2% 41.5%
4411984 2484.1.1.114 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Med13_C 0.65 47.0 3.52e-01 80.0% 32.2%
5024203 330.10.1.0 a+b two layers › dsRBD-like › Heterocyclase TruD C-terminal domain › Heterocyclase TruD C-terminal domain 0.65 51.0 4.58e-01 90.8% 62.2%
3246050 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.64 48.0 4.34e-01 83.1% 58.9%
4171259 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.64 45.0 3.44e-01 75.4% 99.4%
3797649 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.63 48.0 4.09e-01 83.1% 57.3%
4558199 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.63 43.0 3.38e-01 70.8% 40.0%
3606814 896.1.1.0 a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.63 43.0 4.08e-01 75.4% 59.0%
3737835 241.15.1.0 a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain 0.63 49.0 4.28e-01 84.6% 55.0%
3510695 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.63 47.0 4.45e-01 84.6% 66.3%
4945471 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.62 45.0 4.51e-01 76.9% 84.6%
3550970 719.1.1.5 beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › PF27933 0.62 49.0 4.10e-01 84.6% 75.5%
3714703 1021.1.1.0 a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases 0.62 50.0 4.29e-01 87.7% 56.0%
4163583 330.4.1.0 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.62 47.0 4.44e-01 83.1% 70.0%
4108225 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.61 41.0 3.31e-01 70.8% 39.3%
4157358 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.61 46.0 4.40e-01 81.5% 70.5%
3673032 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.61 44.0 4.37e-01 76.9% 80.0%
3655368 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.61 46.0 4.48e-01 86.2% 86.7%
3289794 223.3.1.1 a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase 0.61 47.0 4.03e-01 86.2% 56.4%
4936004 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.61 45.0 3.40e-01 80.0% 100.0%
3797651 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.61 46.0 4.10e-01 80.0% 61.1%
4941649 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 43.0 3.86e-01 78.5% 51.6%
4950038 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.61 47.0 4.42e-01 81.5% 72.5%
3700288 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.61 48.0 4.20e-01 84.6% 100.0%
3602148 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 45.0 3.89e-01 80.0% 100.0%
5049111 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 47.0 3.85e-01 86.2% 46.4%
3982792 330.1.1.14 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › RecT 0.60 43.0 3.42e-01 78.5% 52.0%
3591633 1021.1.1.0 a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases 0.59 49.0 4.04e-01 87.7% 53.6%
3959341 223.3.1.1 a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase 0.59 47.0 3.79e-01 90.8% 70.0%
4034138 7520.1.1.0 a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like 0.59 46.0 3.79e-01 90.8% 85.0%
3960733 330.8.1.1 a+b two layers › dsRBD-like › Rv2632c-like › Rv2632c-like › Rv2632c-like 0.58 48.0 4.47e-01 93.8% 90.6%
3738165 223.2.1.33 a+b three layers › Profilin-like › profilin-like › profilin-like › Fuz_longin_3 0.58 47.0 3.93e-01 93.8% 49.6%
3718300 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.58 43.0 4.15e-01 80.0% 70.7%
5042876 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 45.0 3.81e-01 89.2% 50.8%
4870764 7579.1.1.49 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › GCE_fung 0.58 46.0 2.95e-01 90.8% 30.3%
4359254 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.57 44.0 4.27e-01 86.2% 90.7%
3705153 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 42.0 3.41e-01 90.8% 38.5%
3249582 896.1.1.3 a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › SRP9-21 0.57 42.0 4.04e-01 83.1% 68.0%
3784839 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.57 40.0 3.58e-01 81.5% 49.0%
4944998 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 45.0 3.75e-01 92.3% 48.0%
4336488 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.56 43.0 4.25e-01 84.6% 95.7%
5065158 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 45.0 3.56e-01 92.3% 46.0%
4947581 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 44.0 3.80e-01 89.2% 80.9%
3646441 2484.1.1.205 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27035 0.56 39.0 3.37e-01 75.4% 46.4%
2764515 7579.1.1.49 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › GCE_fung 0.55 43.0 2.74e-01 89.2% 27.7%
5074371 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.55 50.0 3.83e-01 100.0% 91.7%
3461881 223.2.1.15 a+b three layers › Profilin-like › profilin-like › profilin-like › Longin 0.55 43.0 3.60e-01 89.2% 48.8%
5044541 2004.1.1.162 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad51 0.55 46.0 3.09e-01 92.3% 51.0%
4930329 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.55 36.0 4.00e-01 70.8% 90.0%
3728267 244.1.1.35 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › NAD_binding_8 0.54 38.0 2.91e-01 73.8% 41.9%
3399963 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.53 44.0 3.60e-01 90.8% 90.0%
5028178 283.2.1.0 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like 0.53 41.0 2.86e-01 83.1% 76.1%
3461718 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.52 44.0 3.07e-01 96.9% 51.7%
4274357 244.2.1.6 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Rbx_binding 0.52 38.0 3.75e-01 80.0% 74.3%
5032865 244.2.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain 0.52 40.0 3.60e-01 84.6% 79.8%
4983641 2484.1.1.49 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N 0.52 44.0 3.49e-01 100.0% 86.0%
5021439 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.51 37.0 3.63e-01 78.5% 78.7%
4979907 244.2.1.7 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Rubredoxin_C 0.51 38.0 3.35e-01 81.5% 76.5%
3767960 719.1.1.2 beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › XLF 0.50 41.0 3.37e-01 92.3% 68.8%
3881671 719.1.1.2 beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › XLF 0.50 39.0 3.20e-01 84.6% 75.0%
D3 medium residues 247-316
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hl4A01 1.10.8.1310 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.72 55.0 4.28e-01 81.4% 39.0%
2vwaA00 1.20.58.1330 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein 0.71 46.0 4.08e-01 70.0% 47.5%
3cxbA03 1.10.1740.30 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain 0.68 58.0 5.55e-01 94.3% 97.5%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.65 42.0 3.81e-01 70.0% 48.9%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.64 56.0 5.28e-01 98.6% 98.8%
153lA00 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.62 51.0 3.76e-01 95.7% 34.1%
7nafR01 1.10.1200.240 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › 0.62 42.0 4.69e-01 77.1% 100.0%
3t33A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.61 51.0 3.17e-01 91.4% 87.0%
1vq8P03 1.10.1200.60 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › 0.60 45.0 4.96e-01 80.0% 100.0%
3if8B02 1.20.58.730 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 50.0 4.43e-01 91.4% 89.0%
4fwdA02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.60 45.0 4.42e-01 82.9% 91.0%
3nbiA01 1.10.8.1020 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain 0.60 44.0 4.72e-01 82.9% 100.0%
7b7tA01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.59 45.0 3.51e-01 84.3% 94.4%
3c8tA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.58 46.0 4.24e-01 91.4% 84.5%
4qgpB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.57 39.0 3.43e-01 71.4% 69.2%
2a3qA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.56 44.0 3.76e-01 84.3% 71.7%
1td6A03 1.10.472.40 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 0.55 43.0 3.97e-01 87.1% 72.8%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.55 45.0 4.23e-01 85.7% 74.1%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.54 37.0 3.31e-01 71.4% 50.0%
6ygiB01 1.10.4090.10 Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus 0.53 46.0 3.66e-01 97.1% 60.3%
2ewfA02 1.20.1270.310 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 42.0 4.04e-01 88.6% 91.4%
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.52 40.0 3.89e-01 81.4% 96.1%
3dfzA02 1.10.8.610 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › SirC, precorrin-2 dehydrogenase, C-terminal helical domain-like 0.52 40.0 4.01e-01 88.6% 82.4%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4949959 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.79 56.0 5.70e-01 78.6% 74.3%
4363314 101.1.2.485 alpha arrays › HTH › HTH › winged helix domain › DUF2513 0.72 54.0 4.56e-01 80.0% 100.0%
3690355 524.1.1.0 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p 0.70 59.0 4.36e-01 90.0% 37.1%
3421325 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.67 39.0 3.73e-01 70.0% 50.0%
3966804 148.1.3.238 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF815 0.65 47.0 5.02e-01 78.6% 100.0%
3359312 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 39.0 3.87e-01 78.6% 58.7%
2516284 192.3.1.1 alpha bundles › Long alpha-hairpin › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Sod_Fe_N 0.63 42.0 3.78e-01 81.4% 50.0%
3267538 1008.1.1.101 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › NST1 0.63 50.0 4.00e-01 85.7% 74.8%
3928496 143.1.1.0 alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain 0.62 48.0 5.01e-01 87.1% 100.0%
3514804 3722.1.1.0 alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain 0.61 48.0 3.30e-01 84.3% 41.2%
3989810 3291.1.1.5 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Relaxase_C 0.57 39.0 3.45e-01 82.9% 51.6%
4950149 3896.1.2.0 alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase 0.56 43.0 3.28e-01 85.7% 37.1%
3285760 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.55 45.0 3.22e-01 85.7% 33.3%
3036200 108.2.1.0 alpha arrays › EF-hand › Insect pheromone/odorant-binding proteins › Insect pheromone/odorant-binding proteins 0.53 38.0 3.24e-01 77.1% 51.2%
5022551 3788.1.1.0 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) 0.53 36.0 3.11e-01 71.4% 77.5%
1721530 632.23.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I 0.52 40.0 3.93e-01 87.1% 92.3%