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IMGVR_UViG_3300009607_000270-3300009607-Ga0123327_10033121
Arc-VirIMGVR_UViG_3300009607_000270-3300009607-Ga0123327_10033121
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 16-78
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02086.22 best | MethyltransfD12 | 41.6 | 1.70e-10 | 98.4% | 25.5% |
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2g1pB01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.84 | 66.0 | 4.88e-01 | 84.1% | 35.6% |
| 1zq9A01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.76 | 63.0 | 4.57e-01 | 93.7% | 35.6% |
| 4m37A01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.74 | 63.0 | 4.85e-01 | 95.2% | 49.7% |
| 3tkaA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.73 | 57.0 | 4.11e-01 | 85.7% | 32.6% |
| 3lstA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.73 | 61.0 | 4.07e-01 | 93.7% | 25.9% |
| 5eqjB02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.72 | 61.0 | 4.17e-01 | 96.8% | 28.2% |
| 3htxD03 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.72 | 58.0 | 4.01e-01 | 90.5% | 28.5% |
| 3ocjA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.71 | 60.0 | 3.87e-01 | 95.2% | 31.7% |
| 3egeA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.66 | 56.0 | 3.75e-01 | 95.2% | 25.1% |
| 3uhjC01 | 3.40.50.1970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.64 | 51.0 | 3.96e-01 | 92.1% | 40.8% |
| 2n3zA00 | 3.40.50.11230 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.61 | 41.0 | 3.64e-01 | 71.4% | 68.7% |
| 2igtA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.61 | 52.0 | 3.54e-01 | 100.0% | 26.6% |
| 4n0qA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.61 | 49.0 | 3.86e-01 | 93.7% | 58.7% |
| 1i9gA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.60 | 49.0 | 3.54e-01 | 90.5% | 46.7% |
| 3grfA01 | 3.40.50.1370 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase | 0.60 | 41.0 | 3.20e-01 | 73.0% | 32.6% |
| 3cyjA02 | 3.20.20.120 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain | 0.59 | 46.0 | 3.25e-01 | 92.1% | 30.0% |
| 1mzhA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.58 | 47.0 | 3.29e-01 | 93.7% | 47.6% |
| 3by5A00 | 3.30.420.180 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › CobE/GbiG C-terminal domain | 0.58 | 39.0 | 3.27e-01 | 73.0% | 44.7% |
| 5vogA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 41.0 | 3.08e-01 | 81.0% | 41.5% |
| 5ilnA01 | 3.40.50.1370 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase | 0.56 | 40.0 | 2.89e-01 | 77.8% | 26.5% |
| 6lpiD03 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.56 | 40.0 | 3.04e-01 | 79.4% | 66.1% |
| 2vbiA03 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.54 | 38.0 | 2.80e-01 | 74.6% | 56.6% |
| 3on5B02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 41.0 | 3.27e-01 | 90.5% | 63.1% |
| 4cvqA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.54 | 42.0 | 2.98e-01 | 93.7% | 30.6% |
| 3a2bA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.53 | 44.0 | 3.08e-01 | 98.4% | 47.7% |
| 4powA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.50 | 34.0 | 2.92e-01 | 73.0% | 62.2% |
| 1ovmA03 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.50 | 39.0 | 3.02e-01 | 96.8% | 98.9% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5050277 | 2003.1.5.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD | 0.78 | 68.0 | 4.68e-01 | 96.8% | 39.5% |
| 4132755 | 2003.1.5.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD | 0.77 | 66.0 | 4.51e-01 | 95.2% | 37.2% |
| 5078618 | 2003.1.5.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD | 0.76 | 65.0 | 4.52e-01 | 95.2% | 39.5% |
| 4543896 | 2003.1.5.155 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD, Methyltransf_25 | 0.74 | 63.0 | 4.41e-01 | 95.2% | 36.0% |
| 5065356 | 2003.1.5.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD | 0.73 | 62.0 | 4.40e-01 | 95.2% | 41.5% |
| 4231075 | 102.1.1.6 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › Methyltransf_5 | 0.71 | 61.0 | 4.24e-01 | 95.2% | 29.8% |
| 5008702 | 2003.1.5.444 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF1156 | 0.70 | 59.0 | 4.49e-01 | 95.2% | 75.5% |
| 3387321 | 2003.1.5.42 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_21 | 0.69 | 54.0 | 3.55e-01 | 87.3% | 25.1% |
| 4945422 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.68 | 57.0 | 3.86e-01 | 95.2% | 29.2% |
| 5037582 | 2003.1.5.79 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 | 0.67 | 56.0 | 3.92e-01 | 95.2% | 31.6% |
| 4958614 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.67 | 55.0 | 3.99e-01 | 95.2% | 33.2% |
| 4021707 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.66 | 55.0 | 3.70e-01 | 95.2% | 24.3% |
| 5068226 | 7512.1.1.31 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_4 | 0.61 | 49.0 | 3.54e-01 | 92.1% | 67.0% |
| 399812 | 7574.1.1.5 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C | 0.61 | 42.0 | 2.99e-01 | 73.0% | 23.4% |
| 4973839 | 298.4.1.1 ↗ | a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E › vATP-synt_E | 0.58 | 40.0 | 3.63e-01 | 73.0% | 53.3% |
| 4929526 | 7550.1.1.1 ↗ | a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › TP_methylase | 0.58 | 39.0 | 3.38e-01 | 73.0% | 42.7% |
| 4937694 | 3110.1.1.0 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain | 0.57 | 37.0 | 3.27e-01 | 73.0% | 42.9% |
| 4011755 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.56 | 37.0 | 3.04e-01 | 71.4% | 50.0% |
| 4998013 | 3110.1.1.0 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain | 0.54 | 36.0 | 3.32e-01 | 73.0% | 50.0% |
| 3643102 | 2487.1.1.7 ↗ | a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" › PA | 0.53 | 43.0 | 3.40e-01 | 92.1% | 42.9% |
| 4929290 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.53 | 42.0 | 3.42e-01 | 90.5% | 79.2% |
| 4948624 | 3110.1.1.0 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain | 0.51 | 36.0 | 2.84e-01 | 77.8% | 84.2% |
| 1779994 | 7574.1.1.5 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C | 0.51 | 41.0 | 3.07e-01 | 98.4% | 94.3% |
D2
medium
residues 79-152
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2g1pA02 | 1.10.1020.10 | Mainly Alpha › Orthogonal Bundle › Adenine-specific Methyltransferase; domain 2 › Adenine-specific Methyltransferase, Domain 2 | 0.67 | 60.0 | 5.44e-01 | 100.0% | 73.0% |
| 6srbA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 41.0 | 3.59e-01 | 77.0% | 55.0% |
| 2jqtA00 | 1.20.1280.40 | Mainly Alpha › Up-down Bundle › Monooxygenase › HHA | 0.55 | 39.0 | 4.31e-01 | 83.8% | 96.5% |
| 5c4yA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 36.0 | 3.04e-01 | 71.6% | 86.8% |
| 4rncA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.50 | 42.0 | 2.95e-01 | 100.0% | 82.9% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4988477 | 2003.1.5.20 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MethyltransfD12 | 0.74 | 65.0 | 4.28e-01 | 100.0% | 25.0% |
| 4950762 | 2003.1.5.20 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MethyltransfD12 | 0.73 | 62.0 | 4.18e-01 | 100.0% | 25.6% |
| 4006858 | 2003.1.5.20 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MethyltransfD12 | 0.67 | 60.0 | 4.03e-01 | 100.0% | 26.7% |
| 3249620 | 207.1.1.12 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FNIP | 0.58 | 39.0 | 2.33e-01 | 70.3% | 15.3% |
| 3575335 | 109.4.1.415 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RICTOR_V | 0.58 | 40.0 | 2.74e-01 | 74.3% | 28.3% |
| 3881858 | 206.1.1.14 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 | 0.56 | 47.0 | 2.88e-01 | 94.6% | 21.9% |
| 3601454 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 39.0 | 2.35e-01 | 77.0% | 13.0% |
| 3488531 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 39.0 | 2.83e-01 | 81.1% | 57.1% |
| 4025581 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.51 | 39.0 | 3.70e-01 | 83.8% | 92.2% |