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IMGVR_UViG_3300009607_000317-3300009607-Ga0123327_10062663

Arc-Vir

IMGVR_UViG_3300009607_000317-3300009607-Ga0123327_10062663

Quality

66.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 533-650
PDB
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gpiA00 3.30.160.140 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Shew3726-like 0.55 38.0 4.29e-01 87.3% 93.4%
4wiwA02 3.10.50.10 Alpha Beta › Roll › Chitinase A; domain 3 › 0.53 22.0 2.83e-01 73.7% 62.3%
4l5tB02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 31.0 3.44e-01 88.1% 73.6%
1vw5A00 3.30.70.1420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Structure from the mobile metagenome of cole harbour salt marsh: integron cassette protein hfx_cass1 0.52 40.0 3.69e-01 80.5% 97.4%
5karA01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.50 41.0 2.91e-01 90.7% 96.8%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3200164 2498.1.1.102 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › PF30906 0.69 58.0 4.53e-01 89.0% 48.5%
3252321 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.58 52.0 4.74e-01 97.5% 80.0%
3686613 261.1.1.0 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain 0.54 48.0 4.43e-01 99.2% 85.3%
2529893 284.2.1.0 a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain 0.53 22.0 2.77e-01 73.7% 61.4%
3705211 261.1.1.1 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT 0.52 35.0 2.46e-01 89.0% 19.5%
3962117 2008.1.1.215 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF4191 0.51 35.0 3.67e-01 72.0% 97.3%
D2 high residues 663-795
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1td6A03 1.10.472.40 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 0.59 32.0 3.67e-01 99.2% 71.7%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 39.0 4.04e-01 77.4% 77.7%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 32.0 3.64e-01 76.7% 78.1%
1m3qA02 1.10.1670.10 Mainly Alpha › Orthogonal Bundle › Endonuclease Iii, domain 2 › Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 0.55 25.0 3.17e-01 90.2% 70.0%
7w9wA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 41.0 3.31e-01 82.7% 90.8%
2af7D00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.52 34.0 3.58e-01 78.2% 72.7%
2gtvX00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.52 28.0 3.10e-01 75.2% 62.5%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 33.0 3.70e-01 99.2% 83.5%
1r6bX03 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.52 25.0 2.96e-01 92.5% 63.6%
1hciA04 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 31.0 3.32e-01 72.9% 68.4%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 31.0 3.39e-01 72.2% 73.6%
7m2wE01 1.20.120.1900 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain 0.51 36.0 2.75e-01 72.2% 48.7%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5074047 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.55 35.0 3.71e-01 79.7% 70.8%
4250074 140.1.1.5 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.54 41.0 3.56e-01 80.5% 59.5%
4946770 5050.1.1.21 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FTR1 0.53 37.0 3.01e-01 70.7% 63.7%
3588529 162.1.1.1 alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PRD 0.51 30.0 3.38e-01 100.0% 76.0%
3193583 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.50 42.0 4.13e-01 90.2% 90.0%
D3 medium residues 1-66
PDB
D4 medium residues 81-165
PDB
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3lcnB00 1.10.340.40 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain 0.79 66.0 6.31e-01 90.6% 81.4%
3v53E00 1.20.1390.10 Mainly Alpha › Up-down Bundle › PWI domain › PWI domain 0.70 61.0 5.72e-01 95.3% 79.4%
2x3mA00 1.25.40.670 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.69 51.0 4.13e-01 78.8% 54.8%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.69 61.0 5.25e-01 100.0% 73.1%
2xi9A03 1.10.150.480 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.68 59.0 5.62e-01 95.3% 83.2%
4bemJ00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.67 41.0 3.19e-01 100.0% 28.7%
4xxiA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.67 58.0 4.84e-01 95.3% 62.6%
6qs7C01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 39.0 3.32e-01 95.3% 37.9%
1wbeA01 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.65 50.0 3.91e-01 83.5% 77.3%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 39.0 3.68e-01 100.0% 50.5%
7m2wE01 1.20.120.1900 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain 0.62 45.0 3.04e-01 75.3% 43.5%
3f1xA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.62 44.0 3.72e-01 75.3% 65.1%
3ezuA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 38.0 3.00e-01 95.3% 29.7%
2f2cA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 49.0 4.62e-01 96.5% 73.6%
1zp2A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 49.0 4.55e-01 91.8% 69.6%
3lk5A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.59 49.0 3.35e-01 94.1% 84.1%
5a0uA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.59 48.0 2.84e-01 91.8% 59.9%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 42.0 3.93e-01 76.5% 93.6%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 42.0 3.82e-01 77.6% 95.7%
4akgA11 1.20.920.20 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.57 40.0 2.85e-01 74.1% 58.7%
4hl4A01 1.10.8.1310 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.56 42.0 3.50e-01 78.8% 50.7%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 47.0 3.97e-01 90.6% 89.9%
2h8aA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.56 37.0 3.34e-01 100.0% 48.8%
4cybD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 44.0 3.56e-01 88.2% 77.8%
2rkvA02 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.55 38.0 2.91e-01 72.9% 38.6%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.54 39.0 3.56e-01 91.8% 57.3%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.54 39.0 3.34e-01 78.8% 99.3%
3mkzN00 1.10.10.2830 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.53 31.0 2.93e-01 75.3% 44.5%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 41.0 3.46e-01 85.9% 57.1%
2ip6A00 1.20.1440.140 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.52 41.0 4.13e-01 88.2% 87.4%
3nufB00 1.10.1790.10 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › PRD domain 0.52 40.0 3.71e-01 84.7% 67.9%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 39.0 3.54e-01 82.4% 100.0%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 43.0 3.58e-01 92.9% 87.2%
1ohcA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 40.0 3.27e-01 87.1% 46.7%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.50 46.0 3.91e-01 100.0% 76.7%
4gdxA02 1.10.246.130 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain 0.50 37.0 3.37e-01 77.6% 82.0%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
167309 592.2.1.3 alpha arrays › PWI domain-like › YugE-like › YugE-like › Nab2 0.78 66.0 6.18e-01 92.9% 77.1%
3998882 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.77 66.0 6.68e-01 100.0% 94.1%
4926899 101.17.1.0 alpha arrays › HTH › IHF-like DNA-binding proteins › IHF-like DNA-binding proteins 0.74 59.0 5.32e-01 88.2% 91.7%
3784553 592.1.1.6 alpha arrays › PWI domain-like › PWI domain › PWI domain › Nab2 0.73 66.0 6.69e-01 100.0% 100.0%
4027661 592.1.1.1 alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI 0.70 62.0 5.53e-01 98.8% 75.0%
5022215 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.68 50.0 4.42e-01 77.6% 61.6%
4237263 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.68 60.0 5.31e-01 95.3% 73.3%
3166157 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.68 47.0 4.13e-01 72.9% 50.8%
5038898 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.68 57.0 4.65e-01 91.8% 72.9%
4975020 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.67 59.0 4.99e-01 94.1% 68.9%
4027630 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.67 59.0 5.25e-01 95.3% 73.3%
3482861 3361.1.1.6 alpha bundles › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › L27_1 0.66 38.0 3.74e-01 97.6% 53.3%
5042310 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.66 56.0 4.81e-01 94.1% 63.0%
3504717 106.1.1.8 alpha arrays › Globin-like › Globin-like › Globin-like › HisK-N-like 0.66 58.0 4.89e-01 100.0% 68.3%
4317199 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.65 39.0 3.47e-01 96.5% 41.6%
3932046 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.65 40.0 4.00e-01 95.3% 60.0%
3935393 106.1.1.8 alpha arrays › Globin-like › Globin-like › Globin-like › HisK-N-like 0.65 56.0 4.78e-01 100.0% 68.3%
3838451 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.65 56.0 4.62e-01 96.5% 87.7%
4585879 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.64 54.0 4.47e-01 91.8% 86.0%
3950924 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.64 53.0 4.48e-01 90.6% 91.4%
4977916 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.64 57.0 4.07e-01 100.0% 62.8%
5030446 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.63 47.0 4.74e-01 78.8% 95.3%
5026679 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.63 57.0 4.05e-01 100.0% 63.6%
4588604 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 55.0 3.94e-01 100.0% 32.6%
3281265 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.63 52.0 4.41e-01 90.6% 89.3%
4431610 2004.1.1.492 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C, ADDB_N, PF27467 0.61 53.0 3.08e-01 95.3% 12.9%
3296661 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.61 52.0 4.20e-01 95.3% 60.0%
5031906 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.61 54.0 3.93e-01 100.0% 62.0%
3164646 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.60 54.0 3.83e-01 100.0% 61.2%
4008269 5073.1.2.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.60 38.0 2.67e-01 100.0% 19.3%
4639309 5058.1.1.91 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PF27590 0.60 43.0 3.60e-01 100.0% 44.1%
4960130 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.60 48.0 4.73e-01 87.1% 85.6%
3707815 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.60 48.0 4.21e-01 88.2% 72.3%
4828003 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.60 42.0 3.74e-01 100.0% 52.1%
5037061 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.59 52.0 3.82e-01 100.0% 60.4%
4568028 5051.1.1.17 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans 0.59 45.0 2.84e-01 81.2% 57.0%
3800823 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 41.0 3.83e-01 72.9% 84.8%
3700820 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.58 38.0 3.77e-01 100.0% 62.2%
3792010 604.1.1.105 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1_2 0.58 41.0 3.80e-01 72.9% 84.8%
4120251 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.56 49.0 3.59e-01 100.0% 60.8%
3803125 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.54 44.0 3.51e-01 90.6% 73.2%
3874130 133.1.1.5 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › DH_Alsin 0.53 42.0 3.27e-01 90.6% 73.8%
4952865 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.51 41.0 2.91e-01 88.2% 28.1%
3419359 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.51 40.0 3.47e-01 85.9% 76.3%
4961501 629.1.1.1 alpha bundles › TorD-like (Pfam 06192) › TorD-like (Pfam 06192) › TorD-like (Pfam 06192) › Nitrate_red_del 0.50 43.0 3.18e-01 92.9% 98.6%
D5 medium residues 166-233
PDB
D6 medium residues 285-410_472-495
PDB
D7 medium residues 411-471
PDB
Domain cluster: representative
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.71 58.0 5.61e-01 95.1% 79.4%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.70 57.0 5.14e-01 100.0% 65.9%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 52.0 4.35e-01 85.2% 46.7%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 57.0 5.06e-01 95.1% 63.5%
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.69 50.0 3.98e-01 75.4% 40.5%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 48.0 3.85e-01 77.0% 38.9%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.69 53.0 4.72e-01 83.6% 60.9%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.68 51.0 5.47e-01 93.4% 94.2%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.67 55.0 4.72e-01 88.5% 58.5%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.67 52.0 4.92e-01 90.2% 70.3%
6oi7A01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.66 59.0 4.07e-01 98.4% 53.6%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.65 54.0 4.83e-01 90.2% 70.6%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 53.0 5.05e-01 86.9% 78.9%
3r0qA02 2.70.160.11 Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 0.64 52.0 3.63e-01 100.0% 26.4%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 47.0 4.29e-01 80.3% 60.3%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.64 47.0 4.63e-01 85.2% 75.0%
2p1aB01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.64 52.0 3.93e-01 90.2% 90.4%
2avuB00 1.10.4000.10 Mainly Alpha › Orthogonal Bundle › Flagellar transcriptional activator fold › Flagellar transcriptional activator FlhD 0.63 52.0 4.29e-01 88.5% 58.7%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.63 53.0 3.52e-01 96.7% 24.0%
1lp1A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.62 40.0 4.19e-01 72.1% 72.7%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.62 47.0 4.41e-01 83.6% 71.8%
2dceA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 40.0 3.78e-01 100.0% 52.6%
4gczA03 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.62 45.0 4.47e-01 80.3% 73.8%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.62 48.0 4.48e-01 83.6% 68.0%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 55.0 3.99e-01 100.0% 59.0%
3khkB01 1.20.1260.30 Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain 0.62 54.0 4.02e-01 100.0% 39.6%
2vwaA00 1.20.58.1330 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein 0.61 47.0 4.05e-01 93.4% 52.5%
5oklA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.61 44.0 3.71e-01 85.2% 46.5%
3p42A02 6.10.250.2280 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.59 50.0 4.81e-01 95.1% 98.6%
1w36B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 46.0 3.09e-01 86.9% 52.4%
2az0B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.58 41.0 4.02e-01 83.6% 67.6%
1s8nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 45.0 4.63e-01 85.2% 93.1%
1ezjA01 1.10.287.320 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Viral phosphoprotein oligmorisation site domain 0.56 39.0 3.96e-01 83.6% 72.6%
1eteA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 45.0 3.51e-01 90.2% 52.2%
2q9rA01 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.53 42.0 3.02e-01 90.2% 84.6%
1ichA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.52 36.0 3.22e-01 77.0% 49.4%
7z67A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 43.0 3.00e-01 100.0% 88.1%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4913800 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.79 54.0 5.00e-01 100.0% 55.7%
5026124 164.1.1.1 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 0.72 47.0 4.60e-01 85.2% 63.1%
3927560 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.70 49.0 5.03e-01 85.2% 75.0%
4033104 604.15.1.0 alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.70 47.0 4.67e-01 86.9% 66.2%
3180974 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.69 52.0 5.42e-01 88.5% 89.1%
3180166 2003.1.5.63 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CARME 0.68 57.0 3.47e-01 93.4% 48.8%
4304388 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.67 58.0 4.93e-01 100.0% 60.0%
3595457 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.67 53.0 4.76e-01 91.8% 68.9%
3296414 192.29.1.168 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF641 0.66 50.0 4.80e-01 83.6% 70.0%
3391340 109.4.1.83 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf 0.66 50.0 2.90e-01 83.6% 9.1%
3729935 3748.1.1.4 extended segments › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › RPN11_C 0.66 51.0 4.46e-01 83.6% 60.0%
3716291 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.65 52.0 4.70e-01 91.8% 70.0%
3952510 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.65 53.0 4.99e-01 90.2% 76.0%
3594525 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.64 50.0 4.26e-01 90.2% 52.0%
3175723 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 52.0 3.54e-01 91.8% 37.4%
3606174 1117.1.1.0 alpha arrays › Enhancer of polycomb-like protein 1 (Epl1) N-terminal domain › Enhancer of polycomb-like protein 1 (Epl1) N-terminal domain › Enhancer of polycomb-like protein 1 (Epl1) N-terminal domain 0.63 43.0 3.23e-01 95.1% 28.1%
4016806 101.1.10.60 alpha arrays › HTH › HTH › Cyclin-like › DUF2293 0.60 46.0 3.84e-01 85.2% 47.6%
5041271 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.60 50.0 4.68e-01 90.2% 88.0%
3740183 101.1.15.3 alpha arrays › HTH › HTH › HAT1, C-terminal domain › HAT1_C_fung 0.60 47.0 4.01e-01 96.7% 50.5%
3339002 109.4.1.189 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.59 43.0 4.04e-01 77.0% 94.7%
4999401 4995.1.1.0 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like 0.59 41.0 3.65e-01 82.0% 51.8%
3959245 103.12.1.1 alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › ANTAR 0.58 47.0 4.22e-01 88.5% 67.1%
3928811 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.58 49.0 3.12e-01 98.4% 52.1%
3945095 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.57 47.0 4.08e-01 100.0% 60.0%
4854416 5071.1.1.1 alpha bundles › cytochrome bc1 complex 11 kDa protein-like › Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › UCR_hinge 0.56 46.0 4.61e-01 93.4% 90.6%
3406875 518.1.1.0 alpha arrays › Chemotaxis receptor methyltransferase CheR, N-terminal domain › Chemotaxis receptor methyltransferase CheR, N-terminal domain › Chemotaxis receptor methyltransferase CheR, N-terminal domain 0.52 43.0 4.24e-01 93.4% 86.2%
3195918 4336.2.1.1 alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 › EnY2 0.51 43.0 3.74e-01 100.0% 100.0%