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IMGVR_UViG_3300009642_000007-3300009642-Ga0123331_10002362

Arc-Vir

IMGVR_UViG_3300009642_000007-3300009642-Ga0123331_10002362

Identity

Kingdom:
archaea

Quality

83.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-80
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2e1mA01 6.10.250.1500 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.66 22.0 3.17e-01 92.3% 57.9%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5052942 911.1.1.1 ↗ few secondary structure elements › Ferredoxin thioredoxin reductase (FTR), catalytic beta chain › Ferredoxin thioredoxin reductase (FTR), catalytic beta chain › Ferredoxin thioredoxin reductase (FTR), catalytic beta chain › FeThRed_B 0.76 70.0 6.18e-01 100.0% 80.9%
4946438 911.1.1.0 ↗ few secondary structure elements › Ferredoxin thioredoxin reductase (FTR), catalytic beta chain › Ferredoxin thioredoxin reductase (FTR), catalytic beta chain › Ferredoxin thioredoxin reductase (FTR), catalytic beta chain 0.74 67.0 5.99e-01 100.0% 81.8%
3622293 592.1.1.1 ↗ alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI 0.61 36.0 3.82e-01 89.7% 65.7%
3540079 592.1.1.0 ↗ alpha arrays › PWI domain-like › PWI domain › PWI domain 0.60 36.0 3.66e-01 91.0% 58.7%
D2 high residues 114-219
PDB
Domain cluster: representative
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.83 67.0 6.12e-01 84.0% 100.0%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.82 67.0 6.48e-01 87.7% 96.6%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.80 68.0 6.85e-01 89.6% 98.1%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.80 65.0 6.23e-01 85.8% 89.1%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.79 60.0 5.94e-01 80.2% 94.6%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.78 62.0 5.50e-01 84.9% 81.5%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 42.0 4.33e-01 86.8% 56.3%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.76 64.0 6.08e-01 90.6% 95.2%
3ls1A00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.76 65.0 6.05e-01 93.4% 89.5%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 61.0 5.76e-01 89.6% 93.8%
1ug7A00 1.20.120.360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain 0.74 63.0 5.88e-01 90.6% 81.2%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.72 60.0 5.83e-01 90.6% 98.3%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.70 58.0 5.96e-01 88.7% 95.0%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 41.0 3.44e-01 90.6% 35.8%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.69 55.0 4.33e-01 85.8% 99.1%
2uxwA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 49.0 4.56e-01 72.6% 76.9%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 47.0 3.91e-01 70.8% 78.5%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 43.0 4.19e-01 90.6% 59.0%
3bjbD00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 48.0 4.06e-01 77.4% 63.8%
3f1bA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 45.0 3.73e-01 71.7% 56.8%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 38.0 3.91e-01 90.6% 62.4%
4m7cB00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.63 56.0 4.62e-01 100.0% 88.9%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 47.0 3.92e-01 77.4% 63.7%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.63 53.0 4.98e-01 89.6% 95.2%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 45.0 4.43e-01 73.6% 84.7%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.62 52.0 5.01e-01 90.6% 90.7%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.62 48.0 4.58e-01 82.1% 100.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.62 40.0 4.31e-01 91.5% 80.0%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 49.0 4.62e-01 85.8% 100.0%
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 45.0 4.03e-01 78.3% 79.9%
7eqeB01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 45.0 3.92e-01 80.2% 58.6%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.58 34.0 3.54e-01 93.4% 61.5%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.57 40.0 3.96e-01 90.6% 68.8%
3fedA03 1.20.930.40 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Transferrin receptor-like, dimerisation domain 0.56 45.0 4.04e-01 88.7% 100.0%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 44.0 3.30e-01 90.6% 36.9%
5ojcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.55 42.0 3.70e-01 92.5% 54.5%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.55 45.0 4.02e-01 90.6% 90.4%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.54 45.0 4.09e-01 94.3% 71.4%
1jr3C02 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.54 43.0 4.11e-01 85.8% 90.2%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 48.0 3.54e-01 97.2% 78.3%
1or7B01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.53 36.0 3.83e-01 78.3% 79.8%
1urvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 44.0 3.83e-01 87.7% 81.8%
2rfqC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 39.0 3.31e-01 90.6% 47.4%
4gyoB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 41.0 3.78e-01 86.8% 87.1%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3970386 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.86 70.0 6.43e-01 85.8% 98.5%
4988269 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.83 62.0 6.58e-01 78.3% 100.0%
3372899 3684.1.1.2 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.80 70.0 5.21e-01 92.5% 78.4%
5056945 601.18.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.80 70.0 6.80e-01 91.5% 89.6%
4014383 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.80 63.0 5.70e-01 83.0% 100.0%
3655427 601.18.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ 0.79 60.0 5.53e-01 80.2% 79.1%
3633107 5057.1.1.0 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.77 62.0 6.59e-01 90.6% 94.7%
3440212 601.18.1.13 ↗ alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Vwaint 0.77 64.0 6.51e-01 90.6% 88.6%
3981425 5069.1.1.28 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DmsC 0.76 65.0 5.52e-01 90.6% 87.3%
3815161 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.76 52.0 4.56e-01 70.8% 60.6%
4927882 601.18.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.76 60.0 5.93e-01 83.0% 92.7%
3460830 604.16.1.3 ↗ alpha bundles › Spectrin repeat-like › Hypothetical membrane protein Ta0354, soluble domain › Hypothetical membrane protein Ta0354, soluble domain › Vwaint 0.75 64.0 6.49e-01 91.5% 90.5%
2543302 5054.1.1.58 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › YVC1_C 0.75 63.0 5.33e-01 90.6% 73.4%
3802176 604.16.1.3 ↗ alpha bundles › Spectrin repeat-like › Hypothetical membrane protein Ta0354, soluble domain › Hypothetical membrane protein Ta0354, soluble domain › Vwaint 0.75 63.0 6.41e-01 90.6% 89.5%
4271561 5045.1.1.1 ↗ alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.75 66.0 5.11e-01 96.2% 73.0%
3802170 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.75 51.0 4.55e-01 70.8% 69.3%
4927880 601.16.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.74 63.0 6.18e-01 91.5% 93.9%
4929552 601.18.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.74 61.0 5.93e-01 86.8% 91.3%
4879693 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.74 62.0 5.73e-01 90.6% 94.2%
2841860 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.74 61.0 5.55e-01 89.6% 89.5%
3971953 601.3.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.74 60.0 5.62e-01 84.0% 72.8%
3641586 604.12.1.48 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vwaint 0.74 62.0 6.07e-01 91.5% 81.7%
3841891 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.73 61.0 3.67e-01 90.6% 19.3%
4028318 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 60.0 5.65e-01 87.7% 100.0%
3823125 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.73 50.0 4.45e-01 70.8% 76.0%
None — 0.72 61.0 3.71e-01 90.6% 22.0%
None — 0.72 61.0 3.71e-01 90.6% 22.2%
5004728 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.72 50.0 5.15e-01 70.8% 96.0%
4084468 5054.1.1.2 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.72 61.0 4.37e-01 90.6% 47.8%
None — 0.72 61.0 3.65e-01 90.6% 19.9%
3463576 3684.1.1.2 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.71 60.0 4.75e-01 92.5% 79.1%
3278762 633.6.1.1 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.71 49.0 4.27e-01 71.7% 74.2%
2697024 601.3.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.70 58.0 5.68e-01 89.6% 83.5%
3411539 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.70 59.0 4.70e-01 92.5% 69.8%
5082667 633.6.1.1 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.70 49.0 4.49e-01 71.7% 76.3%
4950999 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.69 57.0 5.64e-01 88.7% 90.9%
1563531 633.6.1.6 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C 0.69 49.0 4.45e-01 72.6% 71.9%
3605745 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.67 46.0 3.98e-01 70.8% 93.9%
4986924 632.18.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.65 44.0 4.16e-01 91.5% 59.2%
3972080 4953.1.1.29 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › DUF1631 0.65 37.0 3.17e-01 89.6% 33.7%
5010469 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 51.0 5.20e-01 86.8% 98.1%
3226437 633.6.1.6 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C 0.64 49.0 4.03e-01 79.2% 73.5%
3525931 109.4.1.1421 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_19 0.64 48.0 4.15e-01 79.2% 63.0%
3411860 633.6.1.6 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C 0.64 51.0 4.55e-01 84.9% 78.0%
4933622 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.63 43.0 4.49e-01 70.8% 95.0%
3725025 5001.1.1.125 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF7703 0.63 57.0 4.15e-01 97.2% 78.5%
3286912 632.18.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.63 44.0 4.62e-01 71.7% 80.0%
3932077 633.6.1.0 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.63 52.0 4.34e-01 87.7% 66.3%
3179506 3745.1.1.1 ↗ alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex 0.63 54.0 3.92e-01 96.2% 66.5%
4948341 141.1.1.3 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.62 56.0 4.19e-01 100.0% 92.9%
4025201 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.62 42.0 4.21e-01 93.4% 67.3%
3958131 611.4.1.0 ↗ alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like 0.62 47.0 4.31e-01 79.2% 78.5%
3952252 611.4.1.2 ↗ alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like › Acyl-CoA_dh_C 0.62 47.0 4.25e-01 79.2% 75.7%
3801367 611.2.1.0 ↗ alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) 0.61 44.0 4.24e-01 73.6% 81.7%
3218994 633.6.1.6 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C 0.61 50.0 4.24e-01 86.8% 66.5%
3323416 3831.1.1.7 ↗ alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › DUF842 0.60 43.0 4.35e-01 97.2% 75.2%
3949633 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.59 38.0 3.04e-01 91.5% 34.0%
3735343 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.58 45.0 3.43e-01 82.1% 92.8%
3992894 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 42.0 4.31e-01 75.5% 80.0%
3894567 603.2.1.0 ↗ alpha bundles › STAT-like › STAT › STAT 0.57 40.0 3.29e-01 72.6% 74.2%
5047617 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.56 49.0 3.89e-01 97.2% 92.3%
3381254 109.4.1.2593 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_long, Eplus_motif 0.53 38.0 2.77e-01 73.6% 61.0%
3432743 5069.1.3.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.53 40.0 4.10e-01 89.6% 83.0%
3999647 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 36.0 3.54e-01 75.5% 67.0%
D3 high residues 237-283
PDB
Domain cluster: representative
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6fhpD00 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.75 50.0 4.62e-01 70.2% 69.4%
1aisB01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.73 61.0 4.72e-01 91.5% 56.6%
6pmiF01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.70 58.0 5.03e-01 100.0% 88.7%
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.70 58.0 4.73e-01 100.0% 97.9%
1dcnA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.69 57.0 4.93e-01 91.5% 75.0%
2gfhA02 1.20.120.710 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain 0.69 59.0 4.90e-01 100.0% 69.8%
3f2bA07 6.10.140.1510 Special › Helix non-globular › Helix Hairpins › 0.68 53.0 4.31e-01 89.4% 46.5%
4tq1A03 1.10.246.190 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Autophagy protein Apg5, helix rich domain 0.67 56.0 5.28e-01 97.9% 93.1%
4h8aB01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.66 56.0 5.19e-01 97.9% 96.7%
1a7lA02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.64 53.0 3.62e-01 100.0% 73.9%
4ne4A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.63 49.0 3.38e-01 85.1% 92.2%
2fnaA02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.62 51.0 4.50e-01 100.0% 68.4%
2xdoD00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.61 48.0 2.96e-01 97.9% 86.8%
1sxjE02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 51.0 4.69e-01 100.0% 93.8%
2rc5A02 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.59 40.0 2.80e-01 80.9% 21.1%
2uvgA02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.58 45.0 3.06e-01 95.7% 77.7%
2w9zA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.58 46.0 3.46e-01 93.6% 51.9%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.55 44.0 4.05e-01 97.9% 92.5%
3n98A01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.51 39.0 2.32e-01 85.1% 51.4%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3605979 190.1.1.0 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box 0.92 63.0 5.58e-01 72.3% 52.3%
3597182 190.1.1.0 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box 0.89 61.0 5.01e-01 72.3% 42.5%
3858252 190.1.1.0 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box 0.88 61.0 5.25e-01 72.3% 48.6%
4938496 103.17.1.0 ↗ alpha arrays › RuvA-C › HMG-CoA reductase flap domain › HMG-CoA reductase flap domain 0.76 67.0 6.43e-01 100.0% 89.1%
4239358 327.19.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.73 57.0 4.65e-01 87.2% 73.3%
4986197 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.70 58.0 4.75e-01 95.7% 95.6%
4379615 181.1.1.1 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.69 57.0 5.07e-01 93.6% 70.0%
3276922 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.68 58.0 5.57e-01 100.0% 96.4%
3689909 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.65 56.0 5.10e-01 100.0% 100.0%
4976690 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.64 50.0 4.99e-01 91.5% 98.0%
3216679 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.64 54.0 4.73e-01 100.0% 65.3%
5050239 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.64 52.0 4.58e-01 100.0% 75.6%
3649730 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.63 50.0 4.16e-01 91.5% 66.7%
4945730 3050.1.1.0 ↗ alpha bundles › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain 0.63 51.0 4.21e-01 91.5% 51.1%
3319901 3050.1.1.7 ↗ alpha bundles › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal_L19e_C 0.63 51.0 3.77e-01 91.5% 37.0%
4644501 3090.1.1.2 ↗ few secondary structure elements › Microplusin › Microplusin › Microplusin › PF30034 0.62 45.0 3.84e-01 76.6% 73.3%
4559285 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.62 52.0 4.28e-01 97.9% 67.8%
5051347 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.62 51.0 4.48e-01 95.7% 88.0%
4342279 103.1.1.6 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C 0.60 45.0 4.28e-01 87.2% 76.7%
3347336 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.59 50.0 4.06e-01 100.0% 62.1%
3978820 4952.1.1.1 ↗ alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › Lyase_1 0.58 46.0 3.61e-01 91.5% 66.7%
5055046 4957.1.1.0 ↗ a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit 0.57 46.0 4.35e-01 91.5% 81.7%