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IMGVR_UViG_3300009642_000007-3300009642-Ga0123331_100023637

Arc-Vir

IMGVR_UViG_3300009642_000007-3300009642-Ga0123331_100023637

Quality

85.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-171
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF09250.17 best Prim-Pol 63.7 4.00e-17 93.4% 94.3%
D2 high residues 193-286
PDB
D3 high residues 753-867
PDB
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4jqfA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 42.0 5.05e-01 95.7% 94.5%
2fnaA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 40.0 4.81e-01 100.0% 95.9%
2co5A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 41.0 4.48e-01 99.1% 78.3%
2do7A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 40.0 4.63e-01 100.0% 88.7%
4hqeA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 41.0 4.30e-01 99.1% 73.3%
6cz4A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 36.0 4.07e-01 82.6% 87.2%
4i98C01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 31.0 3.62e-01 96.5% 88.0%
6n3oA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 36.0 4.01e-01 82.6% 91.1%
6sulA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 35.0 3.66e-01 77.4% 75.9%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3944710 101.1.2.85 alpha arrays › HTH › HTH › winged helix domain › TraI_2_C 0.80 70.0 6.92e-01 100.0% 88.3%
3510016 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.71 62.0 6.35e-01 100.0% 97.3%
3325314 101.1.2.10 alpha arrays › HTH › HTH › winged helix domain › Linker_histone 0.71 41.0 5.01e-01 97.4% 92.9%
3741636 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.71 42.0 4.60e-01 98.3% 72.0%
3981665 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.71 62.0 6.36e-01 98.3% 98.2%
4393250 101.1.2.107 alpha arrays › HTH › HTH › winged helix domain › STN1_2 0.70 42.0 5.03e-01 94.8% 90.7%
3905943 101.1.2.107 alpha arrays › HTH › HTH › winged helix domain › STN1_2 0.70 42.0 5.07e-01 95.7% 94.5%
4002772 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 46.0 4.90e-01 100.0% 77.0%
3489856 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.69 43.0 4.92e-01 97.4% 87.5%
3738688 101.1.2.68 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34 0.69 40.0 4.77e-01 98.3% 86.7%
5009770 101.1.2.181 alpha arrays › HTH › HTH › winged helix domain › MCM_C 0.69 42.0 4.89e-01 100.0% 87.5%
5046672 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 42.0 4.29e-01 99.1% 61.7%
3935353 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 40.0 4.64e-01 96.5% 80.7%
5053312 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 40.0 4.39e-01 100.0% 70.5%
3595754 101.1.2.127 alpha arrays › HTH › HTH › winged helix domain › Cullin_Nedd8 0.68 39.0 4.41e-01 95.7% 75.3%
5057164 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 41.0 4.37e-01 98.3% 69.0%
4982781 101.1.2.101 alpha arrays › HTH › HTH › winged helix domain › Cdc6_C 0.67 47.0 4.84e-01 100.0% 75.5%
5010870 101.1.2.181 alpha arrays › HTH › HTH › winged helix domain › MCM_C 0.67 41.0 4.84e-01 100.0% 92.0%
5022936 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.66 43.0 4.41e-01 99.1% 68.2%
4959343 101.1.2.181 alpha arrays › HTH › HTH › winged helix domain › MCM_C 0.66 46.0 5.07e-01 100.0% 92.2%
4955128 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.65 40.0 3.77e-01 100.0% 49.3%
2685 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.65 41.0 4.55e-01 99.1% 80.9%
4251909 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.65 41.0 4.64e-01 100.0% 84.7%
5026783 101.1.2.101 alpha arrays › HTH › HTH › winged helix domain › Cdc6_C 0.64 44.0 4.67e-01 100.0% 81.0%
3283039 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.62 41.0 3.81e-01 100.0% 52.4%
5041736 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.62 39.0 4.60e-01 97.4% 96.0%
5071694 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.61 41.0 4.18e-01 100.0% 70.9%
4387216 101.1.2.59 alpha arrays › HTH › HTH › winged helix domain › DUF480 0.60 39.0 4.34e-01 100.0% 85.6%
4033119 101.1.9.63 alpha arrays › HTH › HTH › Putative DNA-binding domain › Bro-N 0.59 35.0 3.71e-01 87.0% 65.0%
4968340 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.59 42.0 4.63e-01 100.0% 93.3%
5062643 101.1.2.138 alpha arrays › HTH › HTH › winged helix domain › DUF3860 0.59 40.0 4.56e-01 97.4% 98.8%
3608869 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.56 41.0 4.37e-01 100.0% 90.0%
4004166 108.1.1.45 alpha arrays › EF-hand › EF-hand-related › EF-hand › PLCB1-4-like_EFh 0.55 36.0 3.98e-01 95.7% 84.4%
3584275 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 41.0 4.31e-01 100.0% 90.0%
3998556 7577.1.1.3 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.54 43.0 3.04e-01 85.2% 55.1%
5019589 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 36.0 3.45e-01 100.0% 59.3%
2409433 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.53 39.0 2.79e-01 82.6% 26.8%
3785460 101.1.9.0 alpha arrays › HTH › HTH › Putative DNA-binding domain 0.51 41.0 3.87e-01 87.8% 92.1%
D4 medium residues 333-428
PDB
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1uebA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.68 38.0 4.64e-01 88.5% 85.7%
3a5zB01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.61 35.0 4.20e-01 85.4% 85.7%
7oufB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.58 42.0 3.72e-01 78.1% 68.5%
1sr9A02 3.30.160.270 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Alpha-isopropylmalate synthase LeuA, regulatory domain 0.58 47.0 4.04e-01 91.7% 79.9%
2ehgA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.57 41.0 3.69e-01 79.2% 83.9%
3oyyA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.57 37.0 4.43e-01 90.6% 98.5%
4dy0B02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.56 33.0 3.06e-01 100.0% 43.0%
2k4vA00 3.30.160.370 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 0.55 48.0 4.39e-01 95.8% 81.6%
4bs9A05 3.30.160.660 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 40.0 3.87e-01 81.2% 76.3%
4q9cA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 38.0 3.72e-01 74.0% 95.2%
1tuhA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 42.0 3.77e-01 83.3% 87.0%
3f83A03 2.60.40.2040 Mainly Beta › Sandwich › Immunoglobulin-like › CFA/I fimbrial subunit E, pilin domain 0.53 37.0 3.20e-01 72.9% 94.7%
3ga2A00 3.30.2170.10 Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily 0.53 44.0 3.39e-01 94.8% 82.6%
4j8tA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 40.0 3.68e-01 81.2% 86.7%
1lj5A02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.52 31.0 2.73e-01 100.0% 35.7%
3cu3A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 39.0 3.23e-01 78.1% 69.1%
2vt8A00 3.40.1000.30 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › 0.52 40.0 3.53e-01 83.3% 74.1%
5bkaE01 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 37.0 3.36e-01 76.0% 90.2%
3b7cA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 38.0 3.52e-01 78.1% 90.0%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3506428 220.1.1.168 beta barrels › PH domain-like › PH domain-like › PH domain-like › Tmpp129 0.80 48.0 4.22e-01 79.2% 43.0%
3608236 4.1.1.57 beta barrels › SH3 › SH3 › SH3 › EFP_N 0.68 38.0 4.61e-01 85.4% 83.1%
3948387 1104.1.1.1 a+b complex topology › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › DUF927 0.67 60.0 5.22e-01 100.0% 66.0%
4563194 274.1.1.40 a+b two layers › Pili subunits › Pili subunits › Pili subunits › 17kDa_Anti_2 0.65 40.0 4.04e-01 74.0% 61.7%
3212945 4.8.1.0 beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.62 37.0 4.46e-01 79.2% 94.9%
3660202 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.61 46.0 3.63e-01 79.2% 57.9%
3172513 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.60 46.0 3.81e-01 81.2% 54.7%
3789198 10.10.1.2 beta sandwiches › jelly-roll › Lipase/lipooxygenase domain (PLAT/LH2 domain) › Lipase/lipooxygenase domain (PLAT/LH2 domain) › Flo11 0.60 46.0 3.84e-01 81.2% 97.6%
4418351 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.60 37.0 3.61e-01 76.0% 57.1%
4509268 2484.1.1.48 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutS_II 0.59 44.0 3.51e-01 80.2% 49.5%
3499841 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.58 41.0 4.29e-01 83.3% 78.9%
4365857 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.58 43.0 3.57e-01 79.2% 65.6%
3483729 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.58 43.0 3.97e-01 77.1% 75.0%
4534723 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.58 43.0 3.69e-01 81.2% 88.5%
3689305 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 41.0 3.76e-01 74.0% 95.2%
3227176 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.57 44.0 3.99e-01 81.2% 89.8%
4926797 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.57 41.0 3.72e-01 75.0% 62.3%
2725646 4.8.1.29 beta barrels › SH3 › Chromo domain-like › Chromo domain-like › SH3_AEBP2_C 0.57 36.0 3.34e-01 82.3% 49.2%
3516660 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 44.0 4.43e-01 93.8% 84.2%
3924083 2484.1.1.204 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27046, PF27073 0.57 41.0 3.50e-01 78.1% 61.2%
142633 4.1.1.57 beta barrels › SH3 › SH3 › SH3 › EFP_N 0.57 37.0 4.43e-01 90.6% 98.5%
3251342 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.56 41.0 3.82e-01 76.0% 74.2%
4168380 243.1.1.18 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.54 41.0 3.78e-01 82.3% 86.9%
6384 243.1.1.18 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.54 42.0 3.77e-01 83.3% 87.0%
3706903 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.54 39.0 3.34e-01 76.0% 60.1%
3285952 243.1.1.18 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.53 40.0 3.70e-01 82.3% 88.5%
5079413 5.1.3.272 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › SBBP 0.52 37.0 2.82e-01 76.0% 62.6%
5062854 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 43.0 3.04e-01 94.8% 66.0%
3684759 331.3.1.10 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › AtaL 0.51 43.0 3.63e-01 94.8% 72.4%
3657881 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.51 37.0 2.65e-01 78.1% 74.5%
3929507 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.50 38.0 3.88e-01 78.1% 78.9%
3499891 63.1.1.0 beta barrels › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain 0.50 40.0 3.25e-01 91.7% 63.8%
D5 medium residues 429-675
PDB
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ja8204 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 58.0 5.18e-01 92.7% 89.5%
2vsqA04 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 29.0 3.75e-01 76.5% 83.1%
5ul3A01 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.56 32.0 3.93e-01 82.2% 86.5%
2a5yC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 39.0 4.55e-01 78.5% 97.8%
2a3nA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.52 32.0 3.85e-01 75.7% 91.4%
3vkwA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 29.0 3.67e-01 80.6% 89.9%
3knzA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.52 31.0 3.89e-01 73.7% 97.9%
3grfA01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.51 26.0 3.37e-01 74.5% 84.8%
1tzbA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.51 27.0 3.47e-01 74.1% 87.8%
1flaA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.50 29.0 3.73e-01 83.4% 100.0%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018481 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.86 70.0 6.59e-01 83.8% 71.6%
3944606 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.86 70.0 6.65e-01 83.8% 75.4%
3975473 2004.1.1.136 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF927 0.84 69.0 6.51e-01 84.6% 76.6%
4926850 2004.1.1.22 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sigma54_activat 0.78 49.0 6.18e-01 82.6% 100.0%
5064031 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.77 72.0 6.47e-01 97.6% 85.2%
3952423 2004.1.1.339 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF3631 0.76 61.0 5.98e-01 82.2% 77.0%
5013281 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.76 71.0 6.73e-01 97.2% 88.4%
5058121 2004.1.1.1224 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF31144 0.76 71.0 6.58e-01 98.0% 84.0%
3253892 2004.1.1.409 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 0.71 54.0 6.05e-01 81.0% 98.5%
4069782 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.71 50.0 4.89e-01 73.3% 65.7%
4314819 2004.1.1.58 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase 0.70 53.0 5.96e-01 80.2% 98.5%
4002451 2004.1.1.93 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynein_heavy 0.70 45.0 5.12e-01 70.0% 84.3%
4443044 2004.1.1.1014 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF27228 0.70 62.0 5.70e-01 92.7% 92.3%
5010380 2004.1.1.1014 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF27228 0.69 61.0 5.56e-01 92.7% 92.8%
4033843 2004.1.1.313 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › VapE-like_dom 0.69 53.0 5.86e-01 94.7% 100.0%
3610966 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.69 53.0 5.08e-01 78.5% 92.1%
3957998 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.69 49.0 5.37e-01 72.1% 97.1%
3847109 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.68 59.0 5.71e-01 89.5% 100.0%
3959685 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 47.0 5.56e-01 81.0% 100.0%
3290153 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.67 50.0 5.64e-01 85.4% 98.9%
3580698 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.66 46.0 5.36e-01 70.0% 100.0%
4064073 2004.1.1.209 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sigma54_activ_2 0.66 42.0 5.21e-01 81.0% 100.0%
None 0.66 46.0 4.57e-01 70.0% 96.9%
5028302 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.66 49.0 4.44e-01 75.3% 76.2%
5067202 2004.1.1.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.65 48.0 5.47e-01 75.7% 98.9%
5023501 2004.1.1.58 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase 0.64 51.0 5.07e-01 82.2% 96.9%
3186345 2004.1.1.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.64 47.0 5.37e-01 87.0% 100.0%
3784919 2004.1.1.1 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.63 48.0 5.06e-01 78.5% 85.8%
3499656 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 55.0 4.97e-01 93.5% 99.7%
4171287 2004.1.1.162 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad51 0.61 44.0 4.60e-01 73.3% 93.9%
3422750 2004.1.1.56 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.60 43.0 4.37e-01 72.9% 80.0%
None 0.60 50.0 3.94e-01 86.2% 48.0%
4928781 2004.1.1.156 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5 0.60 52.0 4.51e-01 91.1% 67.0%
3778862 2004.1.1.130 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NACHT 0.58 44.0 4.79e-01 78.9% 100.0%
4283836 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.54 39.0 3.66e-01 74.5% 94.3%
1954209 2004.1.1.44 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PRK 0.52 37.0 3.46e-01 71.7% 97.7%
3210764 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.52 31.0 3.78e-01 90.3% 90.0%
3209204 2004.1.1.366 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N 0.52 45.0 4.47e-01 92.7% 100.0%
4992235 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.52 34.0 4.05e-01 80.2% 100.0%
3893891 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.51 34.0 3.73e-01 71.3% 79.5%
3278320 2003.1.1.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.51 33.0 3.83e-01 70.4% 91.2%
D6 medium residues 676-747
PDB
Domain cluster: representative
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2np5D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.81 74.0 5.63e-01 100.0% 51.9%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.79 71.0 5.60e-01 100.0% 59.0%
3g7rA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.79 71.0 5.19e-01 100.0% 44.4%
1kxpD03 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.74 61.0 5.75e-01 97.2% 75.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 48.0 4.57e-01 72.2% 96.5%
3nufB00 1.10.1790.10 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › PRD domain 0.67 59.0 5.14e-01 100.0% 84.8%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.67 54.0 4.76e-01 88.9% 86.1%
1xfiA02 1.20.1700.10 Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like 0.67 56.0 5.24e-01 93.1% 75.6%
7dfeA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.67 52.0 4.36e-01 98.6% 48.8%
4od4A01 1.10.357.140 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase 0.66 56.0 4.48e-01 98.6% 66.7%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 45.0 3.72e-01 72.2% 91.8%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.65 51.0 4.15e-01 87.5% 77.1%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 53.0 4.38e-01 94.4% 61.2%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.63 55.0 4.14e-01 100.0% 62.2%
2f93B00 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.62 41.0 4.48e-01 70.8% 96.1%
3fmsA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.62 54.0 4.41e-01 100.0% 70.2%
3rrkA02 1.20.1460.20 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › 0.61 47.0 3.73e-01 84.7% 71.0%
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 48.0 3.85e-01 88.9% 53.5%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.61 48.0 4.35e-01 90.3% 76.9%
1bbhA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.61 50.0 4.17e-01 93.1% 61.8%
3rlfF01 1.20.58.370 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › MalF N-terminal region-like 0.60 49.0 4.72e-01 100.0% 79.1%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 47.0 4.06e-01 91.7% 63.3%
3ls1A00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.60 47.0 4.03e-01 93.1% 52.6%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.58 42.0 3.53e-01 77.8% 51.9%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 47.0 4.02e-01 94.4% 61.5%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.56 46.0 3.67e-01 93.1% 55.6%
2pv4A00 1.10.3440.10 Mainly Alpha › Orthogonal Bundle › Sama2622-like fold › Sama2622-like 0.56 48.0 3.91e-01 100.0% 64.8%
8e9gJ01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.55 44.0 3.50e-01 100.0% 40.7%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.54 42.0 3.77e-01 91.7% 93.8%
3sykA02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.53 45.0 4.23e-01 95.8% 83.3%
1fc3B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 44.0 3.93e-01 98.6% 76.2%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3513505 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.80 72.0 5.82e-01 100.0% 63.0%
4992024 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.80 55.0 4.59e-01 72.2% 43.3%
1159839 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.79 71.0 6.05e-01 100.0% 72.4%
3280033 191.1.1.17 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_13 0.78 71.0 5.89e-01 100.0% 67.2%
3967978 191.1.1.49 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_13_2 0.78 71.0 6.11e-01 100.0% 76.4%
3998827 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.69 52.0 4.94e-01 88.9% 68.2%
4953656 5054.1.1.68 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport 0.68 53.0 4.07e-01 100.0% 37.5%
None 0.68 50.0 3.35e-01 76.4% 27.4%
4451187 1128.1.1.0 alpha bundles › LYR protein › LYR protein › LYR protein 0.67 50.0 5.22e-01 87.5% 87.7%
3284524 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.67 55.0 4.80e-01 97.2% 59.1%
3809576 103.4.1.5 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 0.66 49.0 5.08e-01 79.2% 95.4%
3394585 2007.1.14.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.64 55.0 4.32e-01 95.8% 70.3%
4981740 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.64 44.0 4.56e-01 88.9% 78.5%
3673391 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.63 48.0 4.72e-01 88.9% 76.2%
4861051 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.63 46.0 4.53e-01 88.9% 71.6%
3787531 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.62 47.0 4.62e-01 88.9% 75.0%
3605419 1189.1.1.3 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › GARP 0.62 49.0 3.57e-01 87.5% 80.0%
3714356 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.62 48.0 4.57e-01 88.9% 72.9%
4457750 3567.1.1.112 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › AI-2E_transport 0.62 50.0 4.35e-01 97.2% 58.2%
3931312 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.61 50.0 4.31e-01 93.1% 68.3%
4114337 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.61 45.0 4.50e-01 87.5% 77.3%
None 0.61 42.0 2.86e-01 72.2% 26.9%
3491190 544.1.1.0 alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 0.61 48.0 4.28e-01 87.5% 91.4%
5033531 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.61 52.0 5.11e-01 100.0% 92.5%
3424034 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.60 49.0 4.01e-01 94.4% 50.7%
3264889 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.60 43.0 4.16e-01 86.1% 65.9%
3930398 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.59 49.0 4.21e-01 95.8% 90.3%
4975860 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.59 46.0 4.44e-01 87.5% 81.2%
5053975 5054.1.1.68 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport 0.59 49.0 3.43e-01 100.0% 90.2%
3272925 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.58 48.0 4.17e-01 98.6% 71.2%
3975940 601.4.1.6 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.58 49.0 3.93e-01 95.8% 72.0%
5044067 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.58 44.0 4.17e-01 84.7% 68.9%
3793073 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.57 44.0 3.94e-01 88.9% 57.3%
3331738 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.56 46.0 4.11e-01 93.1% 72.4%
5074955 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.55 43.0 4.09e-01 88.9% 71.1%
4092432 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.55 44.0 4.03e-01 87.5% 67.4%
4826576 150.1.1.5 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF305 0.55 46.0 4.46e-01 98.6% 87.1%