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IMGVR_UViG_3300009673_000774-3300009673-Ga0116185_100290212
Arc-VirIMGVR_UViG_3300009673_000774-3300009673-Ga0116185_100290212
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 52-113
Domain cluster:
rep: IMGVR_UViG_3300028567_000036-3300028567-Ga0255342_100210419__D34-93
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6tmfT00 | 1.10.60.20 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 | 0.82 | 38.0 | 3.76e-01 | 82.3% | 43.8% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.78 | 56.0 | 4.18e-01 | 75.8% | 80.4% |
| 3b0bB00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.77 | 61.0 | 5.34e-01 | 88.7% | 60.8% |
| 7bqiA01 | 1.20.58.900 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain | 0.77 | 47.0 | 3.47e-01 | 83.9% | 25.8% |
| 3ermB00 | 1.10.10.710 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like | 0.74 | 58.0 | 5.79e-01 | 85.5% | 84.4% |
| 4ixjA01 | 3.30.1300.80 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.71 | 56.0 | 5.19e-01 | 83.9% | 67.5% |
| 3vayA02 | 1.20.120.1600 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 45.0 | 4.06e-01 | 74.2% | 47.1% |
| 4g6dB02 | 6.10.140.1800 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 55.0 | 5.12e-01 | 88.7% | 80.2% |
| 2mabA00 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.69 | 50.0 | 4.20e-01 | 85.5% | 44.0% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.69 | 44.0 | 3.88e-01 | 77.4% | 44.4% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.69 | 52.0 | 4.11e-01 | 80.6% | 71.0% |
| 3f2bA05 | 6.10.50.10 | Special › Helix non-globular › Insulin-like, subunit E › | 0.69 | 44.0 | 4.83e-01 | 72.6% | 83.3% |
| 1ic8A01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.68 | 55.0 | 4.82e-01 | 88.7% | 93.6% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 47.0 | 4.67e-01 | 74.2% | 78.8% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 52.0 | 3.85e-01 | 83.9% | 68.2% |
| 3t98B00 | 6.10.140.1350 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 52.0 | 4.63e-01 | 83.9% | 67.4% |
| 7xpzA01 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.66 | 55.0 | 3.35e-01 | 91.9% | 73.4% |
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.65 | 52.0 | 4.71e-01 | 88.7% | 69.0% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.65 | 52.0 | 4.19e-01 | 83.9% | 49.1% |
| 6fakA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.65 | 45.0 | 4.11e-01 | 72.6% | 53.1% |
| 1s7zA01 | 1.20.120.780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DNA mimic ocr | 0.65 | 47.0 | 4.01e-01 | 82.3% | 45.5% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.65 | 53.0 | 3.24e-01 | 90.3% | 75.2% |
| 4evxA00 | 1.10.1740.240 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.65 | 51.0 | 4.41e-01 | 85.5% | 78.4% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.64 | 46.0 | 3.63e-01 | 75.8% | 35.1% |
| 3ufeA02 | 1.20.58.1950 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 41.0 | 4.43e-01 | 71.0% | 75.5% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.64 | 44.0 | 4.16e-01 | 72.6% | 64.5% |
| 6w6jD01 | 1.10.1780.10 | Mainly Alpha › Orthogonal Bundle › Double Clp-N motif › Clp, N-terminal domain | 0.64 | 47.0 | 3.71e-01 | 79.0% | 71.0% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.64 | 43.0 | 3.34e-01 | 77.4% | 33.3% |
| 1rfyB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.64 | 49.0 | 4.27e-01 | 80.6% | 56.8% |
| 8d7hD01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.63 | 53.0 | 3.79e-01 | 90.3% | 43.9% |
| 1vfpB02 | 1.20.1110.10 | Mainly Alpha › Up-down Bundle › Calcium-transporting ATPase, transmembrane domain › Calcium-transporting ATPase, transmembrane domain | 0.63 | 52.0 | 3.20e-01 | 96.8% | 66.8% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 51.0 | 3.57e-01 | 90.3% | 49.7% |
| 3vw4A01 | 1.10.340.50 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › | 0.61 | 46.0 | 4.14e-01 | 83.9% | 58.7% |
| 1i1rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 51.0 | 3.69e-01 | 90.3% | 59.3% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 50.0 | 3.90e-01 | 90.3% | 73.7% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 52.0 | 4.34e-01 | 95.2% | 56.3% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.60 | 44.0 | 3.38e-01 | 80.6% | 90.1% |
| 2no4A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.59 | 43.0 | 4.05e-01 | 75.8% | 64.0% |
| 5uckB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.59 | 51.0 | 3.29e-01 | 96.8% | 66.2% |
| 1gvfB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.59 | 48.0 | 3.13e-01 | 90.3% | 37.1% |
| 1knzA01 | 6.10.280.20 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Rotavirus non-structural protein NSP3, N-terminal domain | 0.58 | 48.0 | 4.14e-01 | 95.2% | 97.1% |
| 1gakA00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.58 | 42.0 | 3.40e-01 | 80.6% | 37.2% |
| 1f9cA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.58 | 43.0 | 3.49e-01 | 80.6% | 86.1% |
| 1td6A01 | 1.20.1480.10 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › hypothetical protein mp506/mpn330, domain 1 | 0.58 | 42.0 | 3.57e-01 | 77.4% | 86.3% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.58 | 45.0 | 4.18e-01 | 85.5% | 66.7% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 48.0 | 4.10e-01 | 90.3% | 58.3% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 38.0 | 3.59e-01 | 75.8% | 58.1% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 43.0 | 3.66e-01 | 90.3% | 52.9% |
ECOD (40)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3385808 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.79 | 66.0 | 5.38e-01 | 90.3% | 79.1% |
| 5082532 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.78 | 56.0 | 5.41e-01 | 75.8% | 70.0% |
| 4941914 | 4070.1.1.2 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 | 0.78 | 62.0 | 4.27e-01 | 88.7% | 27.2% |
| 3284949 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.76 | 57.0 | 5.49e-01 | 79.0% | 74.3% |
| 3340355 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.76 | 56.0 | 5.46e-01 | 85.5% | 71.4% |
| 3492370 | 4010.1.1.2 ↗ | a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 | 0.75 | 58.0 | 3.69e-01 | 83.9% | 17.3% |
| 3164721 | 1078.1.1.0 ↗ | extended segments › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit | 0.74 | 54.0 | 4.73e-01 | 75.8% | 57.8% |
| 3970007 | 3502.1.1.0 ↗ | alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein | 0.74 | 62.0 | 5.78e-01 | 90.3% | 86.7% |
| 3651508 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.74 | 52.0 | 5.28e-01 | 80.6% | 76.7% |
| 4318836 | 5065.1.1.3 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 | 0.72 | 63.0 | 4.05e-01 | 95.2% | 60.4% |
| 5057998 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.72 | 61.0 | 4.06e-01 | 96.8% | 45.4% |
| 3984343 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.71 | 62.0 | 4.37e-01 | 100.0% | 51.5% |
| 3518379 | 3502.1.1.1 ↗ | alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG | 0.71 | 56.0 | 5.88e-01 | 90.3% | 98.2% |
| 185221 | 3502.1.1.1 ↗ | alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG | 0.70 | 57.0 | 5.56e-01 | 88.7% | 83.6% |
| 3721509 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.69 | 56.0 | 3.70e-01 | 90.3% | 67.4% |
| 3876213 | 1045.1.1.0 ↗ | alpha bundles › Rad50-binding domain of Mre11 › Rad50-binding domain of Mre11 › Rad50-binding domain of Mre11 | 0.68 | 47.0 | 3.91e-01 | 74.2% | 75.5% |
| 3482882 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.67 | 51.0 | 5.26e-01 | 82.3% | 91.7% |
| 3505833 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 55.0 | 3.84e-01 | 90.3% | 88.1% |
| 3593055 | 3542.1.1.0 ↗ | alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases | 0.65 | 56.0 | 3.83e-01 | 100.0% | 80.4% |
| 4531707 | 109.3.1.33 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_3 | 0.65 | 56.0 | 4.12e-01 | 98.4% | 76.0% |
| 5057355 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.65 | 54.0 | 4.12e-01 | 91.9% | 39.9% |
| 4460781 | 5050.1.1.25 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TLC | 0.65 | 52.0 | 3.43e-01 | 88.7% | 20.7% |
| 3690556 | 148.1.1.0 ↗ | alpha arrays › Histone-like › Histone-related › Histone | 0.65 | 50.0 | 5.15e-01 | 88.7% | 86.7% |
| 3274209 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.64 | 56.0 | 4.06e-01 | 95.2% | 35.8% |
| 3973761 | 5050.1.1.22 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like | 0.64 | 49.0 | 3.48e-01 | 83.9% | 43.7% |
| 3281140 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.64 | 52.0 | 3.62e-01 | 88.7% | 43.6% |
| 4276746 | 192.1.1.40 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › VMA21 | 0.63 | 46.0 | 4.55e-01 | 83.9% | 72.1% |
| 5053903 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 49.0 | 4.00e-01 | 85.5% | 45.8% |
| 4610257 | 6130.1.1.0 ↗ | alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain | 0.62 | 47.0 | 4.64e-01 | 82.3% | 78.5% |
| 3290367 | 3470.1.1.0 ↗ | extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain | 0.62 | 48.0 | 4.72e-01 | 82.3% | 84.6% |
| 5058151 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.61 | 51.0 | 5.09e-01 | 96.8% | 95.4% |
| 3591291 | 1076.1.1.1 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like | 0.60 | 52.0 | 3.69e-01 | 100.0% | 35.7% |
| 3653751 | 5058.1.1.11 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › TerC | 0.60 | 52.0 | 3.47e-01 | 95.2% | 27.0% |
| 3552184 | 1045.1.1.1 ↗ | alpha bundles › Rad50-binding domain of Mre11 › Rad50-binding domain of Mre11 › Rad50-binding domain of Mre11 › Mre11_DNA_bind | 0.59 | 48.0 | 4.00e-01 | 88.7% | 77.1% |
| 3329547 | 604.6.1.22 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 | 0.58 | 48.0 | 3.97e-01 | 90.3% | 60.0% |
| 4082855 | 106.1.1.4 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Rsbr_N | 0.58 | 48.0 | 3.68e-01 | 90.3% | 81.4% |
| 3697477 | 7581.1.1.7 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Ketoacyl-synt_C | 0.56 | 47.0 | 2.97e-01 | 95.2% | 58.5% |
| 3209062 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 47.0 | 2.83e-01 | 98.4% | 31.9% |
| 4994844 | 2006.1.1.18 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2 | 0.51 | 43.0 | 3.04e-01 | 98.4% | 62.7% |
| 5010630 | 6132.1.1.0 ↗ | alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain | 0.51 | 36.0 | 3.62e-01 | 88.7% | 75.4% |