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IMGVR_UViG_3300009707_000100-3300009707-Ga0116195_100199810
Arc-VirIMGVR_UViG_3300009707_000100-3300009707-Ga0116195_100199810
Identity
- Kingdom:
- archaea
Quality
80.5
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-96
Domain cluster:
rep: IMGVR_UViG_3300021491_000005-3300021491-Ga0190332_10000154__D9-112
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1o8vA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.68 | 39.0 | 3.49e-01 | 92.6% | 40.6% |
| 1vprA03 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.68 | 42.0 | 3.54e-01 | 91.6% | 38.2% |
| 4i8oA02 | 3.30.160.690 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Bacterial toxin RNase RnlA/LsoA, N repeated domain | 0.66 | 36.0 | 3.72e-01 | 88.4% | 55.6% |
| 1ugiD00 | 3.10.450.20 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Bacteriophage PBS2, uracil-glycosylase inhibitor | 0.62 | 43.0 | 4.61e-01 | 89.5% | 84.1% |
| 3kg8A01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.59 | 51.0 | 4.63e-01 | 95.8% | 89.2% |
| 4g59C02 | 3.30.500.30 | Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › | 0.58 | 47.0 | 4.04e-01 | 89.5% | 93.7% |
| 5bw0F00 | 3.30.1300.30 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like | 0.57 | 35.0 | 3.61e-01 | 80.0% | 63.7% |
| 2ix2B00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.57 | 47.0 | 3.44e-01 | 88.4% | 49.0% |
| 2vt8A00 | 3.40.1000.30 | Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › | 0.57 | 38.0 | 3.37e-01 | 100.0% | 46.2% |
| 1plqA00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.57 | 46.0 | 3.34e-01 | 87.4% | 48.4% |
| 7r5yA01 | 3.40.50.1240 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like | 0.56 | 47.0 | 3.11e-01 | 93.7% | 91.3% |
| 3wirA01 | 2.70.98.40 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain | 0.55 | 45.0 | 3.29e-01 | 87.4% | 48.6% |
| 1by5A02 | 2.40.170.20 | Mainly Beta › Beta Barrel › Maltoporin; Chain A › TonB-dependent receptor, beta-barrel domain | 0.55 | 47.0 | 2.94e-01 | 94.7% | 32.1% |
| 3w9aA00 | 2.60.120.1160 | Mainly Beta › Sandwich › Jelly Rolls › | 0.55 | 49.0 | 3.66e-01 | 98.9% | 83.5% |
| 2w38A01 | 2.120.10.10 | Mainly Beta › 6 Propeller › Neuraminidase › | 0.55 | 49.0 | 3.42e-01 | 100.0% | 45.1% |
| 1914A00 | 3.30.720.10 | Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 | 0.55 | 49.0 | 4.07e-01 | 100.0% | 84.8% |
| 2eigA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 48.0 | 3.66e-01 | 98.9% | 87.8% |
| 5t5lA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 49.0 | 3.67e-01 | 98.9% | 88.2% |
| 4jocA00 | 3.40.50.1240 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like | 0.54 | 43.0 | 2.94e-01 | 86.3% | 93.8% |
| 1dhkB00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 49.0 | 3.86e-01 | 100.0% | 84.1% |
| 4nkbA01 | 3.30.1120.120 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.54 | 43.0 | 4.04e-01 | 100.0% | 71.1% |
| 3uaqB02 | 2.40.160.90 | Mainly Beta › Beta Barrel › Porin › | 0.53 | 44.0 | 3.69e-01 | 89.5% | 87.7% |
| 3pquA02 | 2.40.160.90 | Mainly Beta › Beta Barrel › Porin › | 0.53 | 44.0 | 3.62e-01 | 90.5% | 79.7% |
| 4ntqB00 | 3.30.2450.20 | Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › | 0.53 | 46.0 | 3.97e-01 | 100.0% | 61.4% |
| 1sqhA02 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.53 | 39.0 | 3.62e-01 | 87.4% | 58.8% |
| 4g7nA01 | 3.30.1120.120 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.53 | 42.0 | 3.94e-01 | 100.0% | 68.6% |
| 1uuzB00 | 3.40.1420.10 | Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › Inhibitor of vertebrate lysozyme | 0.52 | 39.0 | 3.54e-01 | 92.6% | 58.6% |
| 3esiA00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.52 | 46.0 | 4.21e-01 | 97.9% | 92.7% |
| 1ux6A02 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 46.0 | 3.62e-01 | 100.0% | 72.1% |
| 3jclA01 | 2.60.120.960 | Mainly Beta › Sandwich › Jelly Rolls › Spike glycoprotein, N-terminal domain | 0.52 | 46.0 | 3.30e-01 | 100.0% | 69.3% |
| 3mbhA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.52 | 44.0 | 3.12e-01 | 92.6% | 50.2% |
| 1lj5A02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.51 | 45.0 | 3.82e-01 | 95.8% | 75.3% |
| 4xw3A00 | 2.60.120.920 | Mainly Beta › Sandwich › Jelly Rolls › SPRY domain | 0.51 | 45.0 | 3.62e-01 | 100.0% | 72.6% |
| 2owpA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.50 | 40.0 | 3.75e-01 | 91.6% | 87.6% |
| 2ou5A00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.50 | 41.0 | 3.36e-01 | 88.4% | 78.9% |
ECOD (51)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4879580 | 71.1.1.2 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA | 0.73 | 40.0 | 3.36e-01 | 89.5% | 33.3% |
| 4026193 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.65 | 49.0 | 5.19e-01 | 96.8% | 91.8% |
| 3217505 | 9.1.1.55 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › DUF7045 | 0.64 | 41.0 | 3.85e-01 | 100.0% | 53.0% |
| 3228340 | 4075.1.1.2 ↗ | a+b complex topology › RGC domain › RGC domain › RGC domain › PF29130 | 0.61 | 50.0 | 4.91e-01 | 88.4% | 97.0% |
| 3989853 | 77.1.1.13 ↗ | beta meanders › open-sided beta-meander › Outer surface protein › Outer surface protein › CFSR | 0.59 | 52.0 | 3.59e-01 | 95.8% | 50.8% |
| 4423905 | 4051.1.1.8 ↗ | a+b two layers › a+b domain in Capz › a+b domain in Capz › a+b domain in Capz › PF26204 | 0.59 | 38.0 | 2.87e-01 | 100.0% | 28.2% |
| 4961766 | 241.15.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › Spo0M | 0.59 | 45.0 | 4.31e-01 | 95.8% | 69.6% |
| 4221174 | 243.19.1.0 ↗ | a+b two layers › Cystatin-like › Phi ETA orf 56-like protein C-terminal domains › Phi ETA orf 56-like protein C-terminal domains | 0.59 | 43.0 | 4.38e-01 | 94.7% | 76.8% |
| 3700022 | 220.1.1.14 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › DM10_dom | 0.59 | 42.0 | 4.14e-01 | 91.6% | 68.6% |
| 3614143 | 292.2.1.1 ↗ | a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › POLO_box | 0.58 | 41.0 | 3.78e-01 | 100.0% | 57.3% |
| 3930399 | 4075.1.1.0 ↗ | a+b complex topology › RGC domain › RGC domain › RGC domain | 0.57 | 47.0 | 4.66e-01 | 88.4% | 96.0% |
| 4026805 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.57 | 51.0 | 4.21e-01 | 98.9% | 77.1% |
| 3849839 | 4210.1.1.0 ↗ | a+b two layers › WGR domain › WGR domain › WGR domain | 0.57 | 42.0 | 4.13e-01 | 89.5% | 73.0% |
| 3310438 | 5.1.4.145 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › TAF1C_beta-prop | 0.56 | 50.0 | 3.22e-01 | 100.0% | 58.5% |
| 3320577 | 10.1.1.2 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Lectin_legB | 0.56 | 50.0 | 3.65e-01 | 98.9% | 86.2% |
| 3962078 | 222.1.1.17 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N | 0.56 | 50.0 | 4.18e-01 | 100.0% | 90.9% |
| 4024938 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.56 | 50.0 | 4.02e-01 | 100.0% | 61.1% |
| 4259150 | 295.1.1.46 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › WapI | 0.56 | 40.0 | 3.60e-01 | 75.8% | 92.6% |
| 3317594 | 10.1.1.2 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Lectin_legB | 0.56 | 50.0 | 3.61e-01 | 98.9% | 82.6% |
| 2769955 | 12.2.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Hyaluronate lyase-like, C-terminal domain › Hyaluronate lyase-like, C-terminal domain | 0.55 | 36.0 | 4.35e-01 | 87.4% | 100.0% |
| 3711843 | 220.1.1.14 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › DM10_dom | 0.55 | 43.0 | 4.08e-01 | 91.6% | 70.4% |
| 4129272 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.54 | 49.0 | 4.30e-01 | 98.9% | 73.6% |
| 1291801 | 1.1.1.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp | 0.54 | 46.0 | 3.52e-01 | 92.6% | 87.2% |
| 3330367 | 9.2.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › DUF2921_N | 0.54 | 45.0 | 3.62e-01 | 90.5% | 64.9% |
| 3606895 | 220.1.1.14 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › DM10_dom | 0.54 | 43.0 | 4.11e-01 | 91.6% | 72.7% |
| 2796077 | 5084.1.1.1 ↗ | beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like › TbpB_B_D | 0.54 | 45.0 | 3.60e-01 | 90.5% | 80.4% |
| 4248012 | 222.1.1.0 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase | 0.54 | 46.0 | 4.11e-01 | 95.8% | 85.7% |
| 3481279 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 43.0 | 4.17e-01 | 91.6% | 77.1% |
| 3458331 | 10.1.1.2 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Lectin_legB | 0.54 | 48.0 | 3.50e-01 | 98.9% | 83.5% |
| 3732226 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 46.0 | 3.81e-01 | 91.6% | 65.0% |
| 3502370 | 1.1.5.47 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Phage_tube_2 | 0.54 | 45.0 | 3.81e-01 | 91.6% | 97.5% |
| 4426474 | 222.1.1.17 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N | 0.53 | 45.0 | 4.04e-01 | 94.7% | 88.9% |
| 3784673 | 220.1.1.190 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PF26660 | 0.53 | 46.0 | 3.80e-01 | 94.7% | 91.5% |
| 3903497 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.53 | 46.0 | 3.78e-01 | 100.0% | 83.2% |
| 3928816 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.53 | 48.0 | 3.21e-01 | 100.0% | 45.3% |
| 4948189 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.52 | 42.0 | 3.89e-01 | 85.3% | 81.4% |
| 3193851 | 3561.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 17 › Mediator of RNA polymerase II transcription subunit 17 › Mediator of RNA polymerase II transcription subunit 17 › Med17 | 0.52 | 41.0 | 2.63e-01 | 97.9% | 17.4% |
| 3558215 | 1.1.1.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp | 0.52 | 43.0 | 2.90e-01 | 91.6% | 49.6% |
| 4996023 | 2.1.1.77 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RNA_pol_RpbG | 0.52 | 42.0 | 3.97e-01 | 86.3% | 84.3% |
| 3279448 | 9.1.1.17 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › MoaF | 0.52 | 43.0 | 3.85e-01 | 93.7% | 63.2% |
| 5040130 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.52 | 37.0 | 3.82e-01 | 73.7% | 100.0% |
| 4399861 | 10.1.1.35 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_3 | 0.52 | 46.0 | 3.39e-01 | 98.9% | 47.3% |
| 4121558 | 10.1.1.25 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Toxin_R_bind_N | 0.52 | 46.0 | 3.35e-01 | 98.9% | 48.9% |
| 3741434 | 1.1.5.30 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_oxase_2 | 0.52 | 42.0 | 3.09e-01 | 88.4% | 87.1% |
| 3267146 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.51 | 46.0 | 3.10e-01 | 100.0% | 48.4% |
| 3877687 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.51 | 42.0 | 3.86e-01 | 92.6% | 90.0% |
| 3788776 | 5.1.4.38 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › ANAPC1 | 0.51 | 46.0 | 3.15e-01 | 100.0% | 52.2% |
| 11122 | 213.2.1.1 ↗ | a+b three layers › Nat/Ivy › Inhibitor of vertebrate lysozyme, Ivy › Inhibitor of vertebrate lysozyme, Ivy › Ivy | 0.51 | 38.0 | 3.52e-01 | 95.8% | 60.5% |
| 3761115 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.51 | 43.0 | 2.86e-01 | 96.8% | 38.8% |
| 3712860 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.50 | 43.0 | 3.95e-01 | 90.5% | 94.2% |
| 3562381 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.50 | 45.0 | 2.90e-01 | 100.0% | 41.0% |
D2
high
residues 212-257
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2k5cA00 | 3.10.20.830 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Bifunctional heparan sulphate n-deacetylase/n-sulphotransferase | 0.71 | 54.0 | 4.39e-01 | 84.8% | 75.0% |
| 3floB00 | 1.10.3200.20 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › DNA Polymerase alpha, zinc finger | 0.70 | 55.0 | 3.67e-01 | 87.0% | 28.9% |
| 4tpuA02 | 2.20.28.10 | Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › | 0.69 | 51.0 | 5.43e-01 | 93.5% | 100.0% |
| 1qxfA00 | 2.20.25.100 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › Ribosomal protein S27 | 0.69 | 55.0 | 5.14e-01 | 91.3% | 84.5% |
| 2xzm600 | 2.20.25.100 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › Ribosomal protein S27 | 0.69 | 55.0 | 4.63e-01 | 91.3% | 63.7% |
| 3vpbE00 | 2.20.28.160 | Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › | 0.68 | 51.0 | 4.82e-01 | 82.6% | 80.4% |
| 6rxpA02 | 3.30.1600.10 | Alpha Beta › 2-Layer Sandwich › SIR2/SIRT2 'Small Domain' › SIR2/SIRT2 'Small Domain' | 0.66 | 49.0 | 3.96e-01 | 87.0% | 40.0% |
| 1jj2Y00 | 2.20.25.30 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.65 | 48.0 | 4.21e-01 | 82.6% | 53.4% |
| 1vziA01 | 2.20.28.100 | Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › Desulphoferrodoxin, N-terminal domain | 0.62 | 43.0 | 4.54e-01 | 89.1% | 92.1% |
| 4ifdI02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.59 | 42.0 | 3.05e-01 | 82.6% | 24.3% |
| 7kggC01 | 3.30.2090.10 | Alpha Beta › 2-Layer Sandwich › Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains › Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | 0.59 | 44.0 | 3.64e-01 | 82.6% | 89.9% |
| 1mhnA00 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.56 | 42.0 | 4.09e-01 | 95.7% | 88.1% |
| 2xzm901 | 6.20.50.180 | Special › Other non-globular › N-terminal domain of TfIIb › | 0.55 | 38.0 | 3.42e-01 | 76.1% | 65.3% |
ECOD (78)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4938180 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.84 | 60.0 | 6.58e-01 | 80.4% | 100.0% |
| 5066735 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.83 | 72.0 | 6.96e-01 | 91.3% | 86.0% |
| 4981580 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.83 | 59.0 | 6.09e-01 | 76.1% | 79.5% |
| 4981108 | 375.1.1.331 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › DUF5817 | 0.83 | 66.0 | 6.67e-01 | 89.1% | 88.9% |
| 3630907 | 376.1.6.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR | 0.81 | 61.0 | 5.37e-01 | 80.4% | 63.1% |
| 3380132 | 375.1.1.200 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-LSD1 | 0.81 | 58.0 | 6.12e-01 | 76.1% | 87.5% |
| 3437513 | 376.1.4.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR | 0.80 | 59.0 | 5.31e-01 | 80.4% | 75.4% |
| 3226800 | 376.1.4.3 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_2 | 0.80 | 58.0 | 5.31e-01 | 80.4% | 60.0% |
| 4968629 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.79 | 56.0 | 5.37e-01 | 76.1% | 66.7% |
| 3933458 | 376.1.4.3 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_2 | 0.79 | 57.0 | 5.43e-01 | 80.4% | 65.5% |
| 3784601 | 376.1.6.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR | 0.79 | 57.0 | 5.81e-01 | 78.3% | 84.4% |
| 4963432 | 4076.2.1.7 ↗ | a+b two layers › L9 N-domain-like › MbtH-like › MbtH-like › DUF5817 | 0.78 | 69.0 | 5.64e-01 | 100.0% | 70.6% |
| 3893608 | 376.1.6.2 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 | 0.78 | 58.0 | 5.12e-01 | 80.4% | 70.6% |
| 3846046 | 221.1.1.195 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › VCIP135_N | 0.78 | 63.0 | 5.62e-01 | 89.1% | 66.2% |
| 4019034 | 375.1.1.22 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › DNA_RNApol_7kD | 0.78 | 58.0 | 6.19e-01 | 91.3% | 92.5% |
| 3213738 | 192.29.1.117 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Ima1_N | 0.77 | 53.0 | 5.91e-01 | 71.7% | 94.3% |
| 3881976 | 375.1.1.142 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › VCIP135_N | 0.77 | 61.0 | 5.38e-01 | 89.1% | 62.9% |
| 5041477 | 375.1.3.3 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › DUF5817 | 0.77 | 68.0 | 6.27e-01 | 100.0% | 96.7% |
| 3040112 | 375.1.1.22 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › DNA_RNApol_7kD | 0.77 | 57.0 | 5.53e-01 | 89.1% | 72.0% |
| 5060491 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.77 | 57.0 | 4.19e-01 | 80.4% | 30.8% |
| 3878932 | 376.1.4.2 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog › IBR_1 | 0.77 | 58.0 | 5.28e-01 | 80.4% | 80.0% |
| 4969798 | 375.1.3.3 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › DUF5817 | 0.77 | 68.0 | 6.43e-01 | 100.0% | 100.0% |
| 3995440 | 375.1.1.211 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Ima1_N | 0.77 | 52.0 | 5.84e-01 | 71.7% | 94.3% |
| 3903614 | 375.1.3.2 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › MRNIP | 0.76 | 66.0 | 5.87e-01 | 97.8% | 80.0% |
| 5029687 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.76 | 55.0 | 5.57e-01 | 78.3% | 93.3% |
| 4263982 | 375.1.1.302 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › MRNIP | 0.76 | 67.0 | 6.34e-01 | 100.0% | 96.4% |
| 5002125 | 375.1.3.3 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › DUF5817 | 0.76 | 66.0 | 6.12e-01 | 100.0% | 95.0% |
| 4475754 | 4076.2.1.5 ↗ | a+b two layers › L9 N-domain-like › MbtH-like › MbtH-like › MRNIP | 0.75 | 67.0 | 5.97e-01 | 100.0% | 81.5% |
| 5030549 | 375.1.3.1 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › DUF1922 | 0.74 | 66.0 | 6.25e-01 | 100.0% | 98.2% |
| 3899324 | 376.1.6.2 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR_1 | 0.74 | 56.0 | 4.46e-01 | 80.4% | 43.3% |
| 3251948 | 375.1.3.2 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Hypothetical protein MTH1184 › MRNIP | 0.74 | 65.0 | 5.98e-01 | 100.0% | 90.0% |
| 3274032 | 375.1.1.211 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Ima1_N | 0.74 | 55.0 | 5.56e-01 | 78.3% | 80.0% |
| 4008953 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.74 | 52.0 | 5.72e-01 | 91.3% | 100.0% |
| 4024048 | 375.1.1.22 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › DNA_RNApol_7kD | 0.74 | 55.0 | 5.48e-01 | 91.3% | 77.1% |
| 3271858 | 376.1.6.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR | 0.74 | 54.0 | 4.87e-01 | 80.4% | 60.0% |
| 3486337 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.73 | 53.0 | 5.04e-01 | 78.3% | 65.5% |
| 4962880 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.73 | 54.0 | 3.45e-01 | 80.4% | 17.3% |
| 3592749 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.72 | 52.0 | 5.27e-01 | 76.1% | 84.4% |
| 3498209 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.72 | 51.0 | 4.64e-01 | 76.1% | 54.7% |
| 3629733 | 375.1.1.211 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Ima1_N | 0.72 | 53.0 | 4.97e-01 | 78.3% | 65.5% |
| 5022494 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.72 | 52.0 | 4.09e-01 | 78.3% | 36.0% |
| 4945986 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.72 | 54.0 | 3.50e-01 | 82.6% | 19.1% |
| 5040368 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.71 | 50.0 | 5.44e-01 | 73.9% | 97.1% |
| 5027043 | 375.1.1.12 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Ribosomal_S27e | 0.71 | 54.0 | 5.50e-01 | 82.6% | 100.0% |
| 5003640 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.71 | 53.0 | 3.50e-01 | 82.6% | 20.5% |
| 5067854 | 101.1.2.22 ↗ | alpha arrays › HTH › HTH › winged helix domain › PCI | 0.70 | 51.0 | 3.69e-01 | 78.3% | 40.8% |
| 4934222 | 375.1.1.12 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Ribosomal_S27e | 0.70 | 56.0 | 4.92e-01 | 89.1% | 72.1% |
| 3638416 | 376.1.4.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Ariadne-1 protein homolog | 0.70 | 55.0 | 5.31e-01 | 91.3% | 76.4% |
| 4111189 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.70 | 54.0 | 4.95e-01 | 84.8% | 65.0% |
| 3909223 | 376.1.6.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR | 0.69 | 57.0 | 5.14e-01 | 93.5% | 89.2% |
| 3718984 | 375.10.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha | 0.69 | 58.0 | 5.18e-01 | 93.5% | 66.2% |
| 5071248 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.69 | 52.0 | 3.37e-01 | 80.4% | 20.0% |
| 4978165 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.69 | 51.0 | 3.37e-01 | 80.4% | 19.5% |
| 4853382 | 375.1.1.138 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › IBR_2 | 0.69 | 50.0 | 4.59e-01 | 80.4% | 60.3% |
| 4979486 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.68 | 52.0 | 3.54e-01 | 80.4% | 23.4% |
| 4979574 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.67 | 51.0 | 3.48e-01 | 82.6% | 24.1% |
| 5036396 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.67 | 48.0 | 5.04e-01 | 76.1% | 89.7% |
| 4960524 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.66 | 55.0 | 5.63e-01 | 100.0% | 100.0% |
| 4981040 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.66 | 47.0 | 4.99e-01 | 76.1% | 89.7% |
| 3517444 | 375.10.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha | 0.65 | 51.0 | 4.57e-01 | 87.0% | 85.3% |
| 3266250 | 376.1.6.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR | 0.65 | 47.0 | 4.41e-01 | 78.3% | 63.3% |
| 4007799 | 2484.1.1.211 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB | 0.65 | 53.0 | 3.54e-01 | 91.3% | 23.7% |
| 5005094 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.64 | 52.0 | 3.44e-01 | 89.1% | 22.1% |
| 3494172 | 2.1.1.51 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › EXOSC1 | 0.63 | 44.0 | 3.12e-01 | 76.1% | 28.1% |
| 3575430 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.63 | 43.0 | 4.26e-01 | 71.7% | 66.0% |
| 5044604 | 101.1.2.22 ↗ | alpha arrays › HTH › HTH › winged helix domain › PCI | 0.61 | 44.0 | 3.37e-01 | 73.9% | 30.1% |
| 5034313 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.61 | 41.0 | 4.40e-01 | 71.7% | 94.3% |
| 5051266 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.60 | 50.0 | 3.27e-01 | 100.0% | 21.3% |
| 4946660 | 386.1.1.420 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › DZR | 0.60 | 52.0 | 4.56e-01 | 100.0% | 64.3% |
| 3587862 | 2484.1.1.211 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605, Cas12f1-like_TNB | 0.60 | 49.0 | 3.30e-01 | 100.0% | 24.0% |
| 5025694 | 2.1.1.287 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Zn_ribbon_TiaS | 0.59 | 43.0 | 3.08e-01 | 91.3% | 23.7% |
| 4979649 | 2003.1.5.19 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › TRM | 0.58 | 48.0 | 2.90e-01 | 100.0% | 22.4% |
| 4650778 | 2008.1.1.20 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Uma2 | 0.55 | 39.0 | 2.73e-01 | 78.3% | 76.1% |
| 394809 | 376.1.3.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD | 0.55 | 37.0 | 3.34e-01 | 71.7% | 70.8% |
| 3223271 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.54 | 41.0 | 3.62e-01 | 97.8% | 54.1% |
| 3626657 | 11.1.1.99 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › V-set | 0.53 | 43.0 | 3.32e-01 | 93.5% | 51.8% |
| 3581246 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 37.0 | 2.99e-01 | 76.1% | 81.0% |
| 3689321 | 376.1.3.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD | 0.52 | 34.0 | 3.06e-01 | 84.8% | 44.3% |
D3
medium
residues 100-156
Domain cluster:
representative
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.90 | 72.0 | 4.96e-01 | 84.2% | 58.3% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.87 | 65.0 | 6.50e-01 | 84.2% | 76.3% |
| 2g2dA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.86 | 69.0 | 4.81e-01 | 84.2% | 38.1% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.85 | 66.0 | 6.39e-01 | 84.2% | 78.1% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.84 | 67.0 | 6.45e-01 | 84.2% | 76.2% |
| 3kkbA00 | 1.20.120.880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain | 0.84 | 79.0 | 5.91e-01 | 100.0% | 58.7% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.84 | 68.0 | 4.11e-01 | 86.0% | 16.3% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.83 | 66.0 | 6.32e-01 | 84.2% | 78.1% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 62.0 | 5.05e-01 | 82.5% | 47.7% |
| 1vx7301 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 59.0 | 5.32e-01 | 84.2% | 59.5% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.80 | 70.0 | 4.89e-01 | 98.2% | 67.4% |
| 3qf7A02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.80 | 64.0 | 6.17e-01 | 86.0% | 79.4% |
| 2qkdA02 | 2.60.120.1040 | Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain | 0.79 | 62.0 | 4.61e-01 | 84.2% | 60.0% |
| 2ccyA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.79 | 61.0 | 4.71e-01 | 84.2% | 39.4% |
| 1ylmA00 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.79 | 69.0 | 5.14e-01 | 98.2% | 85.9% |
| 1ykhA00 | 6.10.140.200 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 62.0 | 5.13e-01 | 84.2% | 52.6% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.78 | 60.0 | 4.95e-01 | 84.2% | 64.7% |
| 2y4tA02 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.78 | 56.0 | 5.84e-01 | 84.2% | 84.6% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.78 | 70.0 | 5.84e-01 | 100.0% | 92.8% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.77 | 70.0 | 5.63e-01 | 100.0% | 78.5% |
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.77 | 67.0 | 5.05e-01 | 98.2% | 77.0% |
| 2yb5F01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.77 | 69.0 | 5.95e-01 | 98.2% | 75.6% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.74 | 63.0 | 4.85e-01 | 96.5% | 80.3% |
| 1b06A01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.73 | 58.0 | 5.51e-01 | 86.0% | 85.1% |
| 1t5oA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.73 | 51.0 | 3.80e-01 | 75.4% | 29.8% |
| 2l35A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.73 | 55.0 | 5.36e-01 | 84.2% | 74.6% |
| 2j9wB00 | 1.20.120.1130 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain | 0.73 | 65.0 | 5.40e-01 | 100.0% | 89.9% |
| 4nv0A02 | 1.10.150.340 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain | 0.72 | 52.0 | 4.70e-01 | 80.7% | 54.9% |
| 2oauA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 52.0 | 4.36e-01 | 80.7% | 63.7% |
| 2o7tA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.70 | 62.0 | 4.32e-01 | 100.0% | 63.2% |
| 2ptfB02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.67 | 53.0 | 5.39e-01 | 91.2% | 94.7% |
| 1krrA00 | 2.160.10.10 | Mainly Beta › 3 Solenoid › UDP N-Acetylglucosamine Acyltransferase; domain 1 › Hexapeptide repeat proteins | 0.67 | 58.0 | 3.97e-01 | 98.2% | 51.5% |
| 6t0bc01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 49.0 | 4.53e-01 | 82.5% | 65.4% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 55.0 | 4.62e-01 | 100.0% | 76.1% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.65 | 57.0 | 3.89e-01 | 100.0% | 40.4% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 54.0 | 4.62e-01 | 100.0% | 100.0% |
| 2gsvA00 | 6.10.140.40 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 49.0 | 4.75e-01 | 84.2% | 76.1% |
| 1vibA00 | 1.10.287.120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like | 0.64 | 46.0 | 4.72e-01 | 80.7% | 90.9% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.62 | 51.0 | 4.74e-01 | 100.0% | 92.4% |
| 3hgtA00 | 3.40.50.12360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 49.0 | 3.17e-01 | 100.0% | 27.3% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.55 | 43.0 | 3.68e-01 | 87.7% | 94.0% |
| 1irxA05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.53 | 40.0 | 3.57e-01 | 89.5% | 78.5% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3372432 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.89 | 71.0 | 6.23e-01 | 84.2% | 60.0% |
| 3595968 | 605.2.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 | 0.88 | 70.0 | 6.16e-01 | 84.2% | 77.5% |
| 3250208 | 4207.1.2.1 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › Med7 | 0.88 | 71.0 | 5.22e-01 | 84.2% | 36.9% |
| 4000253 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.88 | 70.0 | 4.58e-01 | 84.2% | 22.9% |
| 4406905 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.87 | 69.0 | 6.43e-01 | 84.2% | 71.4% |
| 3794775 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.87 | 67.0 | 6.41e-01 | 84.2% | 72.3% |
| 3961630 | 101.1.2.456 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_MmpR5 | 0.86 | 68.0 | 4.78e-01 | 84.2% | 31.2% |
| 3735296 | 603.5.1.0 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like | 0.84 | 62.0 | 4.15e-01 | 77.2% | 31.3% |
| 4975983 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.84 | 74.0 | 5.36e-01 | 94.7% | 81.4% |
| 3577937 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.82 | 74.0 | 5.78e-01 | 100.0% | 79.1% |
| 3406588 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.81 | 75.0 | 5.07e-01 | 100.0% | 63.3% |
| 3503210 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.81 | 63.0 | 5.75e-01 | 84.2% | 64.0% |
| 3576432 | 5055.1.1.0 ↗ | extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel | 0.81 | 72.0 | 5.40e-01 | 96.5% | 87.7% |
| 3580312 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.78 | 62.0 | 5.27e-01 | 87.7% | 52.6% |
| 3386706 | 221.8.1.0 ↗ | a+b two layers › beta-Grasp › GfcC › GfcC | 0.78 | 59.0 | 4.50e-01 | 82.5% | 36.2% |
| 3171100 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.77 | 70.0 | 5.76e-01 | 100.0% | 89.0% |
| 3640483 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.76 | 64.0 | 4.22e-01 | 93.0% | 28.1% |
| 3453715 | 603.1.1.118 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF7610 | 0.76 | 66.0 | 5.72e-01 | 98.2% | 88.9% |
| 3806943 | 375.1.9.21 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase › DUF3754 | 0.76 | 57.0 | 5.06e-01 | 82.5% | 58.8% |
| 3768971 | 192.29.1.11 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA | 0.76 | 65.0 | 5.30e-01 | 98.2% | 89.1% |
| 3193852 | 150.5.1.57 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PF27758 | 0.75 | 58.0 | 3.86e-01 | 84.2% | 72.9% |
| 3737781 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.75 | 65.0 | 5.39e-01 | 100.0% | 80.0% |
| 3688219 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.75 | 64.0 | 4.12e-01 | 100.0% | 46.6% |
| 4941369 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.75 | 57.0 | 4.71e-01 | 84.2% | 56.2% |
| 3571018 | 109.4.1.1138 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SCAI | 0.74 | 67.0 | 4.43e-01 | 100.0% | 28.0% |
| 3845513 | 7575.1.1.8 ↗ | a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like › SCAI | 0.74 | 67.0 | 4.43e-01 | 100.0% | 28.0% |
| 3808261 | 3826.1.1.27 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › DUF3754 | 0.74 | 56.0 | 4.92e-01 | 82.5% | 58.8% |
| 4402843 | 604.1.1.20 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › AKNA | 0.74 | 63.0 | 5.12e-01 | 100.0% | 87.0% |
| 3318280 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.74 | 63.0 | 4.69e-01 | 100.0% | 75.5% |
| 3172105 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.74 | 66.0 | 5.26e-01 | 100.0% | 68.2% |
| 3738337 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.73 | 64.0 | 5.27e-01 | 100.0% | 81.0% |
| 4975245 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.73 | 63.0 | 5.55e-01 | 100.0% | 85.2% |
| 3262164 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.73 | 64.0 | 4.15e-01 | 100.0% | 38.5% |
| 3481965 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.72 | 57.0 | 4.13e-01 | 89.5% | 62.9% |
| 3935024 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.72 | 53.0 | 3.86e-01 | 78.9% | 30.0% |
| 3733478 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.71 | 61.0 | 3.98e-01 | 98.2% | 92.2% |
| 4076369 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.71 | 53.0 | 3.43e-01 | 84.2% | 79.6% |
| 3962505 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.70 | 53.0 | 3.48e-01 | 82.5% | 19.2% |
| 3711600 | 604.9.1.0 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 | 0.70 | 53.0 | 4.76e-01 | 86.0% | 60.0% |
| 184933 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.69 | 60.0 | 4.85e-01 | 98.2% | 80.0% |
| 3953704 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.67 | 53.0 | 4.02e-01 | 91.2% | 87.3% |
| None | — | 0.67 | 56.0 | 3.50e-01 | 100.0% | 31.0% | |
| 4354962 | 3390.1.1.0 ↗ | extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT | 0.67 | 49.0 | 5.12e-01 | 84.2% | 96.0% |
| 3827397 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.64 | 49.0 | 4.05e-01 | 89.5% | 85.2% |
| 3992719 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.63 | 55.0 | 4.77e-01 | 100.0% | 95.6% |
D4
medium
residues 157-211
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4hwtA02 | 3.40.50.800 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain | 0.70 | 61.0 | 4.86e-01 | 98.2% | 86.4% |
| 3uh0A02 | 3.40.50.800 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain | 0.66 | 54.0 | 4.29e-01 | 96.4% | 87.9% |
| 6g80B01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.63 | 37.0 | 2.46e-01 | 80.0% | 14.5% |
| 2hc5A01 | 3.30.160.170 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › FlaG-like | 0.63 | 48.0 | 4.11e-01 | 89.1% | 70.4% |
| 1vqzA01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.62 | 50.0 | 3.28e-01 | 89.1% | 55.4% |
| 6iw6B01 | 1.10.1410.10 | Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › | 0.57 | 40.0 | 2.72e-01 | 76.4% | 29.8% |
| 2uz8A01 | 3.40.30.90 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › | 0.56 | 40.0 | 4.11e-01 | 81.8% | 98.1% |
| 3weeB03 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.55 | 37.0 | 2.95e-01 | 70.9% | 61.7% |
| 4h17A00 | 3.40.50.850 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like | 0.54 | 45.0 | 3.08e-01 | 92.7% | 76.1% |
| 1wxcB01 | 3.30.1880.10 | Alpha Beta › 2-Layer Sandwich › protein ne1242 fold › protein ne1242 domain like | 0.51 | 39.0 | 3.80e-01 | 85.5% | 75.8% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3497972 | 1021.1.1.0 ↗ | a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases | 0.68 | 47.0 | 4.11e-01 | 72.7% | 49.4% |
| 4933113 | 101.1.9.150 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain › Cas12f1-like_TNB | 0.66 | 50.0 | 3.98e-01 | 81.8% | 41.8% |
| 3177024 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.63 | 49.0 | 3.94e-01 | 85.5% | 56.4% |
| 1874629 | 231.1.1.2 ↗ | a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Molybdenum cofactor-binding domain › MoCoBD_2 | 0.59 | 48.0 | 2.94e-01 | 89.1% | 27.8% |
| 5039705 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.59 | 52.0 | 3.45e-01 | 98.2% | 48.2% |
| 3575976 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.58 | 47.0 | 3.41e-01 | 87.3% | 46.2% |
| 3937568 | 376.1.1.37 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › SLX1_C | 0.58 | 50.0 | 4.40e-01 | 100.0% | 88.2% |
| 3932006 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.57 | 45.0 | 3.52e-01 | 85.5% | 54.8% |
| 4503505 | 376.1.1.37 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › SLX1_C | 0.56 | 48.0 | 3.80e-01 | 100.0% | 92.5% |
| 3485806 | 376.1.1.37 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › SLX1_C | 0.55 | 47.0 | 4.12e-01 | 96.4% | 94.1% |
| 3598129 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.55 | 38.0 | 3.41e-01 | 74.5% | 84.0% |
| 3803377 | 7.1.1.7 ↗ | beta barrels › PDZ domain › PDZ domain › PDZ domain › PDZ_3 | 0.54 | 46.0 | 3.59e-01 | 100.0% | 43.8% |
| 4991161 | 2.21.1.0 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) | 0.54 | 37.0 | 3.04e-01 | 72.7% | 46.7% |
| 3212468 | 214.1.1.0 ↗ | a+b two layers › SH2 › SH2 › SH2 | 0.51 | 35.0 | 3.03e-01 | 76.4% | 98.0% |