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IMGVR_UViG_3300010346_002756-3300010346-Ga0116239_100105641

Arc-Vir

IMGVR_UViG_3300010346_002756-3300010346-Ga0116239_100105641

Identity

Kingdom:
archaea

Quality

76.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 11-52_80-119
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3fd0A01 3.90.1150.60 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Methioning gamme-lyase, C-terminal domain 0.63 47.0 3.55e-01 78.0% 45.6%
2om6A02 1.10.150.400 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.62 44.0 4.50e-01 81.7% 77.2%
3lynB00 1.20.150.10 Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein 0.59 50.0 4.38e-01 95.1% 85.5%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.58 47.0 3.41e-01 87.8% 54.9%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.57 46.0 4.81e-01 89.0% 98.7%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.57 45.0 4.32e-01 84.1% 83.7%
2qvwA04 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.56 43.0 3.60e-01 82.9% 65.5%
3iieB03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.56 46.0 4.62e-01 93.9% 88.2%
3ed5A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.56 40.0 4.05e-01 80.5% 75.0%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 39.0 4.09e-01 80.5% 81.3%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.55 37.0 3.97e-01 73.2% 86.6%
3jvoA00 1.10.3230.30 Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › Phage gp6-like head-tail connector protein 0.54 41.0 3.99e-01 84.1% 72.9%
1xwrC00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.54 39.0 4.02e-01 76.8% 80.3%
1tw9F02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 40.0 3.58e-01 79.3% 57.9%
3natA01 3.40.50.11250 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Protein of unknown function DUF3013 0.53 43.0 3.61e-01 90.2% 75.5%
1bccH00 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.53 35.0 3.78e-01 74.4% 84.8%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 39.0 2.91e-01 81.7% 73.0%
1evyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.52 45.0 3.74e-01 96.3% 96.6%
1wvuA01 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.52 45.0 3.77e-01 100.0% 79.7%
2jnsA01 1.20.1270.220 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 37.0 3.74e-01 75.6% 75.3%
2wyhB04 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.52 39.0 3.70e-01 82.9% 80.2%
4b1bA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 41.0 2.62e-01 87.8% 66.4%
1xo0A01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.51 36.0 3.25e-01 73.2% 66.7%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3289653 191.1.1.8 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_33 0.69 47.0 4.01e-01 78.0% 44.6%
3199170 223.2.1.9 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › Sedlin_N 0.61 48.0 3.86e-01 86.6% 59.4%
3862724 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.60 44.0 4.15e-01 80.5% 85.7%
3392333 3998.1.1.1 ↗ alpha arrays › Peptidase inhibitors family I29 › Peptidase inhibitors family I29 › Peptidase inhibitors family I29 › Inhibitor_I29 0.59 40.0 4.47e-01 91.5% 96.7%
4278712 5058.1.1.16 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.58 40.0 3.71e-01 70.7% 61.9%
3273600 601.20.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Apolipophorin-III › Apolipophorin-III 0.58 45.0 3.40e-01 86.6% 88.9%
3793248 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.57 39.0 3.13e-01 70.7% 72.1%
4393120 192.29.1.2 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Turandot 0.56 43.0 3.84e-01 81.7% 65.2%
4990692 7064.1.1.0 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 0.56 41.0 3.33e-01 78.0% 78.1%
3201001 601.25.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.56 42.0 3.26e-01 82.9% 81.5%
3289405 191.1.1.44 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_43 0.54 38.0 3.37e-01 82.9% 47.7%
3600676 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.54 48.0 4.34e-01 98.8% 87.3%
1558678 170.2.1.1 ↗ alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein N-terminal domain › Retrovirus capsid protein N-terminal domain › Gag_p24 0.53 42.0 3.76e-01 86.6% 64.2%
3976541 101.1.4.6 ↗ alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › Phage_CII 0.53 37.0 3.93e-01 79.3% 85.7%
3210160 386.1.1.261 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF26082 0.53 46.0 3.90e-01 95.1% 60.2%
4930318 101.1.4.3 ↗ alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3 0.53 40.0 3.45e-01 80.5% 60.0%
3518497 102.1.3.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain 0.52 44.0 3.46e-01 96.3% 57.3%
4927627 148.1.3.19 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 0.52 42.0 3.91e-01 89.0% 78.1%
3239603 5063.1.1.0 ↗ alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.51 41.0 3.85e-01 85.4% 95.0%
3909225 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.51 46.0 4.15e-01 100.0% 91.8%
D2 high residues 124-141_161-308
PDB
Domain cluster: rep: LC168164.1__BAV39265.1__BPT24_139__00139__D154-306
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gpjA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.60 34.0 4.19e-01 78.9% 89.0%
3mcaA03 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.59 37.0 4.53e-01 92.8% 100.0%
4pmwA02 2.40.50.700 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.56 21.0 2.89e-01 81.9% 65.4%
1r5bA03 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.54 36.0 4.25e-01 92.8% 100.0%
4g1vA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.54 34.0 3.99e-01 84.3% 89.8%
3zugB02 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.53 36.0 3.83e-01 78.3% 78.2%
1d7bA00 2.60.40.1210 Mainly Beta › Sandwich › Immunoglobulin-like › Cellobiose dehydrogenase, cytochrome domain 0.51 38.0 3.68e-01 75.3% 98.4%
1ci0B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.51 39.0 3.72e-01 81.3% 75.5%
2v9kA04 3.30.70.3190 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 33.0 3.86e-01 85.5% 99.1%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4085589 1.1.7.17 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.68 31.0 4.37e-01 74.7% 88.7%
4429352 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.68 32.0 4.30e-01 74.7% 83.3%
3599398 1.1.8.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain 0.61 37.0 4.65e-01 89.8% 99.0%
4571200 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.61 34.0 4.27e-01 84.3% 89.0%
3698630 1.1.8.4 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain › eIF2_C 0.60 38.0 4.68e-01 90.4% 100.0%
109 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.59 33.0 4.11e-01 84.3% 88.1%
4400928 1.1.7.10 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase 0.59 37.0 4.14e-01 79.5% 81.6%
3786547 1.1.8.11 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain › GTP-eEF1A_C 0.58 37.0 4.51e-01 90.4% 100.0%
3731870 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.50 38.0 3.07e-01 78.3% 85.7%
D3 medium residues 319-366_538-556
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07068.18 best Gp23 24.9 1.80e-05 97.0% 12.3%
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4q5eA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.69 46.0 4.45e-01 100.0% 61.3%
2pt7G02 3.30.1370.180 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.64 40.0 4.09e-01 100.0% 64.2%
1dq3A04 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.63 37.0 3.14e-01 100.0% 34.2%
2vs7A02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.63 38.0 3.60e-01 100.0% 50.0%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.62 39.0 3.62e-01 100.0% 49.4%
1b24A01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.61 40.0 3.58e-01 100.0% 46.3%
7sk7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 50.0 3.39e-01 92.5% 75.9%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.60 37.0 3.52e-01 100.0% 51.2%
3jcmH04 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.58 34.0 3.31e-01 100.0% 49.4%
4v1al00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.58 37.0 3.05e-01 100.0% 33.1%
6abqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 39.0 3.40e-01 71.6% 92.5%
3g87A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.57 33.0 3.31e-01 100.0% 55.2%
2x3gA00 3.30.70.1910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 37.0 3.15e-01 100.0% 37.9%
1weyA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 39.0 3.44e-01 100.0% 46.2%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.57 42.0 3.85e-01 100.0% 59.8%
5dcaA11 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 40.0 3.37e-01 73.1% 55.2%
1kafA00 3.90.1150.20 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription regulator MotA, C-terminal domain 0.54 33.0 2.81e-01 85.1% 34.3%
2g0iA00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.54 40.0 3.44e-01 100.0% 48.6%
1cc8A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 35.0 3.49e-01 100.0% 63.9%
4nb5B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 34.0 3.21e-01 89.6% 51.8%
2joeA01 3.30.1830.10 Alpha Beta › 2-Layer Sandwich › YehR-like fold › YehR-like 0.52 39.0 3.10e-01 100.0% 40.6%
2if1A00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.52 34.0 2.94e-01 100.0% 35.7%
4r78A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 32.0 2.89e-01 85.1% 40.6%
2y8yA01 3.30.70.1200 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 0.52 39.0 3.68e-01 100.0% 65.1%
4i68A00 3.30.70.1800 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 32.0 3.01e-01 100.0% 46.7%
5zneA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 34.0 3.41e-01 100.0% 64.4%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.51 35.0 3.06e-01 97.0% 46.2%
3znuA00 3.30.70.1060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel 0.51 37.0 3.38e-01 100.0% 55.3%
3broD00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 36.0 2.83e-01 74.6% 95.5%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3417366 312.1.1.19 ↗ a+b three layers › HIT-like › HIT-related › HIT-related › PF26216 0.66 40.0 3.07e-01 100.0% 28.6%
3206607 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.66 46.0 4.60e-01 100.0% 71.4%
5038034 304.120.1.6 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.64 46.0 4.18e-01 100.0% 56.7%
5035783 304.120.1.6 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.61 44.0 4.15e-01 100.0% 63.7%
3580419 3914.1.1.2 ↗ alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer 0.61 52.0 2.97e-01 95.5% 13.7%
5011969 304.115.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in DAHP synthase › Ferredoxin-like domain in DAHP synthase 0.61 36.0 3.80e-01 98.5% 65.0%
3686938 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.60 40.0 3.76e-01 100.0% 54.1%
3213842 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.60 51.0 3.43e-01 98.5% 40.0%
3214019 5001.1.1.41 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.60 54.0 3.40e-01 100.0% 75.8%
5082452 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.59 50.0 3.37e-01 92.5% 69.0%
5022357 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.58 36.0 3.81e-01 100.0% 68.3%
4992385 304.120.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.57 35.0 3.49e-01 100.0% 57.1%
4379259 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.57 46.0 3.97e-01 100.0% 54.1%
3391335 304.5.1.0 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.57 43.0 3.92e-01 100.0% 60.0%
3933114 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 51.0 3.22e-01 100.0% 66.0%
3258706 812.1.1.0 ↗ a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain 0.56 49.0 3.95e-01 100.0% 53.3%
3420416 101.1.2.245 ↗ alpha arrays › HTH › HTH › winged helix domain › PORR 0.56 38.0 2.93e-01 70.1% 94.6%
3319253 101.1.2.137 ↗ alpha arrays › HTH › HTH › winged helix domain › OST-HTH 0.55 40.0 3.60e-01 76.1% 76.7%
1888715 101.1.2.135 ↗ alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.55 37.0 2.91e-01 70.1% 97.1%
3396525 327.11.2.20 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › BICC1_KH 0.54 38.0 3.74e-01 100.0% 66.7%
5072613 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 36.0 3.78e-01 100.0% 76.7%
5884 327.1.1.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Alpha-lytic protease prodomain › Alpha-lytic protease prodomain 0.54 35.0 3.37e-01 91.0% 56.2%
3470890 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 42.0 3.60e-01 83.6% 66.7%
3738318 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.53 37.0 3.50e-01 70.1% 91.3%
5006365 101.1.2.143 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.52 35.0 3.25e-01 89.6% 54.1%
5029842 101.1.2.645 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_40 0.52 34.0 2.93e-01 89.6% 41.9%
4025389 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.52 45.0 3.57e-01 95.5% 88.9%
3289139 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.52 43.0 3.69e-01 100.0% 56.5%
3521467 3016.1.1.21 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › PDXDC1-like_cen 0.51 46.0 4.19e-01 100.0% 74.4%
3940990 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.51 35.0 3.49e-01 100.0% 68.6%
3322650 101.1.2.245 ↗ alpha arrays › HTH › HTH › winged helix domain › PORR 0.51 33.0 3.29e-01 89.6% 62.9%
2319350 327.16.1.3 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › Secretin_N 0.51 34.0 3.37e-01 100.0% 63.4%
4506985 328.3.1.2 ↗ a+b two layers › IF3-like › Translation initiation factor IF3, C-terminal domain › Translation initiation factor IF3, C-terminal domain › mIF3 0.51 38.0 3.39e-01 100.0% 53.3%
3602557 101.1.2.143 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_34 0.50 34.0 3.13e-01 92.5% 52.2%
D4 medium residues 367-425
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ttqA03 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 43.0 2.91e-01 86.4% 84.3%
5xc5A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 40.0 2.95e-01 81.4% 35.9%
2lc4A00 2.30.30.830 Mainly Beta › Roll › SH3 type barrels. › 0.54 42.0 3.43e-01 86.4% 67.6%
2y7bA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 36.0 2.86e-01 76.3% 73.9%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3600530 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 44.0 3.08e-01 84.7% 33.2%
3491281 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.57 40.0 3.01e-01 78.0% 64.2%
5049254 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 38.0 2.93e-01 72.9% 50.3%
3484810 508.1.1.1 ↗ a+b three layers › Protein interacting with HSP90 1 (Pih1) N-terminal domain › Protein interacting with HSP90 1 (Pih1) N-terminal domain › Protein interacting with HSP90 1 (Pih1) N-terminal domain › PIH1 0.55 39.0 3.06e-01 79.7% 54.5%
3825435 70.3.1.1 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.54 38.0 2.76e-01 74.6% 67.9%
3266052 2004.1.1.19 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.54 39.0 3.03e-01 94.9% 32.4%
3599857 4178.1.1.0 ↗ beta sandwiches › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain 0.54 37.0 2.95e-01 74.6% 87.7%
3580573 508.1.1.1 ↗ a+b three layers › Protein interacting with HSP90 1 (Pih1) N-terminal domain › Protein interacting with HSP90 1 (Pih1) N-terminal domain › Protein interacting with HSP90 1 (Pih1) N-terminal domain › PIH1 0.53 39.0 2.94e-01 81.4% 60.0%
4972346 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 42.0 3.62e-01 93.2% 96.2%
4063634 4.1.1.17 ↗ beta barrels › SH3 › SH3 › SH3 › Ribosomal_L19 0.53 40.0 3.16e-01 83.1% 44.4%
3997327 3315.1.1.0 ↗ a+b complex topology › Insertion domain in O-GlcNAc transferase › Insertion domain in O-GlcNAc transferase › Insertion domain in O-GlcNAc transferase 0.51 38.0 3.39e-01 84.7% 72.6%
4931231 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.51 43.0 3.06e-01 98.3% 53.5%
4158399 2492.1.1.2 ↗ a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › JAB 0.51 38.0 2.76e-01 84.7% 57.9%
3415540 11.1.1.108 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › C2-set_2 0.50 40.0 3.34e-01 96.6% 67.2%
3959362 101.1.1.531 ↗ alpha arrays › HTH › HTH › Three-helical HTH › WS_DGAT_cat 0.50 36.0 2.79e-01 79.7% 72.7%
3924581 382.1.1.0 ↗ few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like 0.50 36.0 3.20e-01 78.0% 58.9%
D5 medium residues 426-537
PDB
Domain cluster: rep: OM971649.1__UQJ95486.1__ALHIDCOG_00098__00098__D34-154
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07068.18 best Gp23 55.9 6.80e-15 99.1% 27.5%
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pk8A00 3.30.2320.10 Alpha Beta › 2-Layer Sandwich › hypothetical protein PF0899 fold › hypothetical protein PF0899 domain 0.78 55.0 6.00e-01 91.1% 87.2%
1yueA03 3.30.2320.40 Alpha Beta › 2-Layer Sandwich › hypothetical protein PF0899 fold › 0.73 58.0 5.68e-01 91.1% 76.9%
3dktA02 3.30.2320.10 Alpha Beta › 2-Layer Sandwich › hypothetical protein PF0899 fold › hypothetical protein PF0899 domain 0.70 47.0 5.05e-01 87.5% 81.1%
2dm9A00 3.30.2320.30 Alpha Beta › 2-Layer Sandwich › hypothetical protein PF0899 fold › ATP synthase, E subunit, C-terminal 0.66 44.0 4.34e-01 91.1% 64.4%
6xgpB01 3.30.1930.10 Alpha Beta › 2-Layer Sandwich › capsid protein of prophage fold › capsid protein of prophage domain 0.65 55.0 5.18e-01 91.1% 87.3%
1wz2A04 3.30.2320.20 Alpha Beta › 2-Layer Sandwich › hypothetical protein PF0899 fold › Class I aminoacyl-tRNA synthetases (RS) 0.62 47.0 5.22e-01 84.8% 100.0%
3bqwA02 3.30.1930.10 Alpha Beta › 2-Layer Sandwich › capsid protein of prophage fold › capsid protein of prophage domain 0.62 52.0 4.84e-01 90.2% 81.0%
2ajaA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.60 42.0 2.93e-01 71.4% 29.4%
6vq6I01 3.30.2320.30 Alpha Beta › 2-Layer Sandwich › hypothetical protein PF0899 fold › ATP synthase, E subunit, C-terminal 0.59 43.0 4.44e-01 91.1% 78.7%
3k12D00 3.30.1330.40 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › RutC-like 0.58 41.0 4.10e-01 82.1% 69.2%
4x9xA02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.58 40.0 3.92e-01 81.2% 65.5%
2kdxA00 3.30.2320.80 Alpha Beta › 2-Layer Sandwich › hypothetical protein PF0899 fold › 0.58 48.0 4.78e-01 89.3% 100.0%
5l16A01 3.30.1330.10 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › PurM-like, N-terminal domain 0.55 42.0 4.08e-01 86.6% 73.2%
1ofuA02 3.30.1330.20 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Tubulin/FtsZ, C-terminal domain 0.55 39.0 4.26e-01 83.9% 90.3%
1tzpB00 3.30.1380.10 Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › 0.55 43.0 3.40e-01 94.6% 40.3%
3oajA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.54 41.0 3.84e-01 81.2% 76.4%
4xjxA04 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 43.0 3.35e-01 91.1% 72.2%
2cb0A01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.53 42.0 3.76e-01 85.7% 77.2%
1zh8A02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.52 42.0 3.63e-01 87.5% 70.9%
3euwA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.52 40.0 3.35e-01 84.8% 60.1%
3o1iD02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 37.0 3.40e-01 77.7% 80.1%
3e18A02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.51 41.0 3.44e-01 90.2% 72.2%
3v5nB02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.51 38.0 3.27e-01 79.5% 73.4%
3moiA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.51 40.0 3.35e-01 86.6% 96.1%
1y0bB01 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 35.0 2.91e-01 70.5% 85.8%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3583655 2485.3.1.5 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › Gp23 0.81 76.0 5.31e-01 100.0% 34.7%
11367 2485.3.1.6 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › ENCP4 0.78 55.0 6.00e-01 91.1% 87.2%
4995674 2485.3.1.5 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › Gp23 0.76 71.0 5.31e-01 100.0% 50.8%
4884207 2485.3.1.7 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › Major_capside 0.72 60.0 4.37e-01 95.5% 34.1%
3949155 2485.3.1.11 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › SrpI-like 0.71 59.0 4.42e-01 92.9% 37.7%
4559262 298.4.1.0 ↗ a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E 0.69 42.0 4.32e-01 90.2% 61.8%
5083079 2485.3.1.3 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › Phage_capsid 0.69 55.0 3.90e-01 92.9% 28.9%
4070529 298.4.1.1 ↗ a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E › vATP-synt_E 0.69 42.0 3.77e-01 90.2% 43.1%
4313471 2485.3.1.11 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › SrpI-like 0.68 58.0 4.21e-01 93.8% 34.3%
3075730 2485.3.1.0 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 0.68 61.0 4.33e-01 97.3% 37.0%
4638799 298.4.1.0 ↗ a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E 0.67 42.0 4.05e-01 90.2% 55.2%
4995654 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.67 46.0 5.27e-01 81.2% 100.0%
1877546 2485.3.1.0 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 0.67 58.0 4.18e-01 93.8% 34.7%
5025399 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.67 46.0 5.43e-01 83.9% 100.0%
4502816 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.66 46.0 5.31e-01 89.3% 100.0%
4889260 2485.3.1.12 ↗ a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › DUF6260 0.66 54.0 4.07e-01 94.6% 37.0%
3387325 298.4.1.2 ↗ a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E › FliH 0.65 40.0 3.43e-01 89.3% 38.9%
3838428 298.4.1.2 ↗ a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E › FliH 0.64 39.0 3.84e-01 89.3% 55.8%
4099448 298.4.1.1 ↗ a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E › vATP-synt_E 0.63 36.0 3.79e-01 89.3% 61.0%
5049382 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.63 48.0 5.33e-01 84.8% 100.0%
3644907 7590.1.1.2 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi 0.62 37.0 3.80e-01 72.3% 61.9%
4959577 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.62 47.0 5.23e-01 84.8% 100.0%
4932467 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.62 46.0 5.08e-01 83.9% 97.8%
3199775 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.61 51.0 5.39e-01 91.1% 99.0%
5059401 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.59 43.0 4.91e-01 82.1% 100.0%
4099576 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.59 38.0 4.37e-01 83.9% 96.0%
4964660 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.58 41.0 4.07e-01 71.4% 78.3%
3289587 3008.1.1.0 ↗ a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.56 46.0 4.84e-01 85.7% 100.0%
4946440 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 46.0 3.83e-01 92.0% 97.0%
4577908 7579.1.1.25 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › FSH1 0.54 40.0 3.09e-01 78.6% 57.6%
3601193 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 44.0 3.38e-01 92.0% 87.7%