Back to structures

IMGVR_UViG_3300010351_000965-3300010351-Ga0116248_100050297

Arc-Vir

IMGVR_UViG_3300010351_000965-3300010351-Ga0116248_100050297

Quality

68.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-81
PDB
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.83 64.0 4.36e-01 80.2% 78.5%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.75 56.0 4.96e-01 80.2% 68.1%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 56.0 4.79e-01 80.2% 63.8%
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.75 56.0 4.56e-01 80.2% 60.3%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 54.0 4.61e-01 77.8% 65.6%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 54.0 4.04e-01 80.2% 40.5%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.71 54.0 4.29e-01 80.2% 88.7%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.71 52.0 5.21e-01 77.8% 89.0%
2l81A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.71 54.0 4.20e-01 81.5% 51.1%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 53.0 3.73e-01 80.2% 81.3%
3ckcA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.71 54.0 3.96e-01 82.7% 38.2%
2cz2A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.70 53.0 4.58e-01 81.5% 65.9%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 50.0 3.51e-01 76.5% 73.0%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 57.0 5.71e-01 100.0% 89.4%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.69 50.0 4.72e-01 76.5% 84.5%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.69 52.0 4.72e-01 80.2% 85.3%
3rkoG00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 52.0 4.88e-01 82.7% 70.0%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.67 46.0 4.03e-01 80.2% 45.0%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 51.0 4.48e-01 81.5% 61.2%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.66 59.0 5.32e-01 100.0% 97.3%
2radA03 1.20.1440.30 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain 0.66 57.0 5.02e-01 100.0% 87.4%
2c42A06 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.66 51.0 3.30e-01 100.0% 17.9%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 49.0 4.31e-01 81.5% 59.7%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.65 46.0 5.07e-01 98.8% 96.8%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.64 51.0 4.57e-01 90.1% 72.3%
1kqfC00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.63 48.0 3.59e-01 82.7% 56.9%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 48.0 4.26e-01 82.7% 87.5%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.63 51.0 4.23e-01 87.7% 86.4%
1st6A03 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.63 54.0 4.00e-01 98.8% 59.4%
2xvtC00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.62 45.0 4.63e-01 77.8% 79.7%
3craA02 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.62 43.0 3.74e-01 76.5% 46.1%
3jsbA01 1.20.1440.300 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain 0.61 52.0 5.21e-01 100.0% 95.1%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.60 53.0 3.91e-01 98.8% 65.9%
4u04B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 38.0 3.72e-01 79.0% 58.0%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 44.0 4.15e-01 82.7% 98.0%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.57 45.0 4.06e-01 85.2% 94.6%
4od4A01 1.10.357.140 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase 0.57 49.0 3.97e-01 96.3% 67.3%
3o39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 42.0 4.04e-01 88.9% 99.0%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.53 45.0 3.89e-01 100.0% 60.3%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.52 42.0 4.29e-01 100.0% 100.0%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3963743 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.82 63.0 5.75e-01 81.5% 84.8%
3419702 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.81 73.0 5.86e-01 100.0% 60.6%
3711337 632.24.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › GBS CAMP factor C-terminal domain › GBS CAMP factor C-terminal domain 0.80 57.0 6.31e-01 87.7% 92.3%
4964135 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.75 57.0 5.33e-01 81.5% 74.0%
5065731 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.75 52.0 4.97e-01 72.8% 68.4%
3695977 3922.1.1.133 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PRM1 0.74 51.0 4.70e-01 71.6% 86.7%
3728650 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.73 55.0 5.84e-01 79.0% 100.0%
4458494 3684.1.1.23 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › CA109-like 0.72 55.0 4.31e-01 82.7% 68.0%
3784312 5001.1.1.39 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 0.72 63.0 4.17e-01 100.0% 55.7%
3711300 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.71 54.0 4.33e-01 80.2% 49.7%
3743463 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.71 53.0 3.88e-01 80.2% 78.2%
3573786 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.70 54.0 4.03e-01 82.7% 36.0%
3739436 601.4.1.12 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B 0.70 54.0 4.53e-01 82.7% 62.2%
3204692 5001.1.1.39 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 0.70 52.0 3.62e-01 80.2% 72.5%
5075878 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.69 51.0 5.21e-01 80.2% 83.7%
3173292 7111.1.1.1 alpha bundles › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiq_cyt_C_chap 0.69 49.0 3.65e-01 74.1% 33.5%
3276289 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.68 60.0 4.42e-01 100.0% 84.9%
3282520 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.68 44.0 4.69e-01 74.1% 75.7%
5004497 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 55.0 3.38e-01 87.7% 18.4%
3617266 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.67 50.0 4.45e-01 80.2% 80.0%
3224284 603.3.1.0 alpha bundles › STAT-like › CAPPD, an extracellular domain of amyloid beta A4 protein › CAPPD, an extracellular domain of amyloid beta A4 protein 0.67 49.0 3.90e-01 79.0% 72.0%
3312027 603.1.1.156 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PGG 0.67 51.0 4.32e-01 80.2% 70.8%
4993210 3755.3.1.635 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PHA_synth_III_E 0.66 47.0 3.64e-01 75.3% 38.4%
3788311 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 50.0 4.48e-01 81.5% 85.2%
3458978 632.15.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › GAUT_1 0.66 53.0 5.25e-01 86.4% 82.4%
3685114 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.66 56.0 4.96e-01 95.1% 86.7%
3732670 5001.1.1.39 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 0.66 58.0 3.98e-01 100.0% 75.5%
5083776 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.65 50.0 4.79e-01 82.7% 88.4%
3915925 5069.1.3.98 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ARL6IP6 0.65 50.0 4.72e-01 81.5% 87.8%
4018124 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.65 49.0 3.52e-01 80.2% 72.9%
4569730 5069.1.1.74 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › UPF0093 0.65 48.0 3.77e-01 79.0% 72.6%
3598368 6132.1.1.0 alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain 0.64 53.0 4.12e-01 91.4% 70.0%
4325832 129.1.1.5 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › Ferric_reduct 0.62 56.0 4.05e-01 98.8% 93.2%
3373671 192.1.1.19 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › Hobbit 0.61 44.0 4.16e-01 76.5% 93.0%
3467450 9.1.1.34 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › PAP_fibrillin 0.61 46.0 3.57e-01 81.5% 92.8%
4606152 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.58 45.0 3.56e-01 84.0% 86.5%
4116939 2004.1.1.525 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_27, SbcC_Walker_B 0.56 48.0 3.01e-01 100.0% 21.9%
D2 medium residues 82-154
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2fu2A00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.81 70.0 6.92e-01 95.9% 98.7%
1eq1A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.70 61.0 4.76e-01 100.0% 74.7%
2oo2A00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.67 49.0 4.89e-01 78.1% 85.5%
2km6A00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.65 55.0 5.15e-01 100.0% 100.0%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 45.0 4.09e-01 75.3% 94.2%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.63 47.0 3.87e-01 79.5% 47.1%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.63 43.0 3.79e-01 72.6% 62.3%
1v9vA01 1.20.1480.20 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › MAST3 pre-PK domain-like 0.62 51.0 4.76e-01 94.5% 98.9%
5gmkZ01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 43.0 3.08e-01 74.0% 46.1%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 53.0 4.67e-01 100.0% 65.2%
3rvyA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 51.0 4.58e-01 100.0% 67.3%
4u04B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 40.0 3.82e-01 72.6% 59.1%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 41.0 3.72e-01 76.7% 86.8%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 40.0 3.15e-01 76.7% 71.7%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.55 39.0 3.62e-01 76.7% 94.9%
3v53E00 1.20.1390.10 Mainly Alpha › Up-down Bundle › PWI domain › PWI domain 0.53 45.0 4.03e-01 94.5% 70.6%
4hfkB00 1.20.120.1620 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 42.0 3.84e-01 93.2% 78.6%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4011783 633.21.1.25 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF7598 0.70 61.0 4.86e-01 100.0% 74.2%
3686452 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.70 51.0 4.42e-01 78.1% 69.6%
3323862 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.69 49.0 4.79e-01 75.3% 96.2%
5035274 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.66 55.0 4.76e-01 95.9% 85.0%
4983663 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.65 50.0 4.78e-01 82.2% 95.2%
1503721 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.65 46.0 4.10e-01 76.7% 82.9%
4942288 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.64 48.0 4.41e-01 82.2% 87.0%
5028028 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.64 45.0 3.79e-01 76.7% 74.8%
5012659 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.63 53.0 4.83e-01 95.9% 93.0%
4027661 592.1.1.1 alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI 0.55 47.0 4.00e-01 94.5% 65.8%
3906253 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.54 45.0 3.95e-01 100.0% 79.2%
D3 medium residues 155-233
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.78 63.0 5.54e-01 87.3% 98.3%
1td6A01 1.20.1480.10 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › hypothetical protein mp506/mpn330, domain 1 0.73 60.0 5.58e-01 92.4% 78.4%
2qsbA00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.70 57.0 5.62e-01 89.9% 90.6%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 51.0 5.15e-01 78.5% 94.9%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.69 57.0 3.79e-01 94.9% 87.6%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 53.0 5.17e-01 89.9% 98.8%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 46.0 4.06e-01 74.7% 95.9%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.65 38.0 3.73e-01 96.2% 52.9%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.65 49.0 4.29e-01 82.3% 69.4%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.63 54.0 4.36e-01 100.0% 91.7%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 46.0 4.08e-01 83.5% 80.5%
2kmgA00 3.30.70.3580 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Antirestriction protein 0.61 51.0 4.27e-01 94.9% 91.5%
2x1dA02 1.10.10.2120 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.59 36.0 3.74e-01 83.5% 64.9%
4rg9B04 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 44.0 4.22e-01 82.3% 83.3%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 50.0 4.24e-01 97.5% 74.5%
2kiwA01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.56 44.0 4.37e-01 87.3% 100.0%
2p9xA00 1.10.1200.200 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Protein of unknown function DUF3227 0.56 45.0 4.23e-01 89.9% 90.8%
2x6hA01 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.56 39.0 3.09e-01 74.7% 64.0%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 43.0 3.99e-01 92.4% 64.3%
2imiB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 38.0 3.20e-01 74.7% 47.9%
3lxuX06 1.25.40.710 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 44.0 3.15e-01 98.7% 69.4%
2kjgA00 1.20.120.970 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.50 39.0 3.70e-01 87.3% 75.8%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3530696 109.4.1.942 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NOT1_connector 0.79 68.0 4.88e-01 93.7% 45.0%
3605615 174.1.1.51 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › SCAMP 0.76 64.0 4.88e-01 92.4% 90.6%
4863592 633.21.1.1 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 0.74 63.0 5.63e-01 93.7% 87.4%
2512963 633.21.1.1 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 0.73 64.0 5.43e-01 97.5% 78.0%
2448606 109.4.1.1286 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 0.69 49.0 3.18e-01 75.9% 23.3%
4930112 3558.1.1.0 alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain 0.68 49.0 4.84e-01 75.9% 97.6%
1701031 633.27.1.1 alpha bundles › Bromodomain-like › Four-helical bundle in acetyl-CoA carboxylase › Four-helical bundle in acetyl-CoA carboxylase › ACC_central 0.68 55.0 5.43e-01 89.9% 96.4%
3693457 109.3.1.242 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Fungal_trans_2 0.66 49.0 3.88e-01 79.7% 45.5%
3248680 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 51.0 4.69e-01 92.4% 83.6%
4681455 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 50.0 4.23e-01 92.4% 75.9%
5074457 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.61 49.0 4.47e-01 87.3% 70.5%
3272997 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 44.0 3.38e-01 77.2% 59.5%
3709846 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 51.0 4.00e-01 96.2% 73.1%
3544325 109.27.1.1 alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › BACK 0.57 39.0 3.63e-01 72.2% 57.3%
3474099 5000.3.1.1 alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.55 43.0 3.49e-01 89.9% 70.0%
D4 medium residues 234-293_355-365
PDB
Domain cluster: representative
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3v9fA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.64 46.0 3.00e-01 74.6% 37.8%
6p2kB01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.64 50.0 3.15e-01 85.9% 81.5%
3d31A02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.62 35.0 4.08e-01 94.4% 82.6%
7qi3A01 3.30.2140.20 Alpha Beta › 2-Layer Sandwich › Arylamine N-acetyltransferase fold › 0.62 46.0 3.01e-01 80.3% 63.7%
7x36A01 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.61 52.0 3.41e-01 95.8% 96.3%
2gcjA01 2.30.29.150 Mainly Beta › Roll › PH-domain like › 0.61 41.0 3.43e-01 70.4% 94.0%
6x05A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.61 50.0 3.15e-01 90.1% 48.3%
3qijB03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 45.0 4.21e-01 78.9% 98.9%
4a2lB01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.61 50.0 3.32e-01 91.5% 93.9%
4ifsA01 2.30.29.150 Mainly Beta › Roll › PH-domain like › 0.61 41.0 3.41e-01 70.4% 95.5%
5gtqA00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.60 51.0 3.38e-01 95.8% 90.9%
1ki1B02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.60 44.0 3.60e-01 80.3% 93.7%
6eotD01 2.140.10.30 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › Dipeptidylpeptidase IV, N-terminal domain 0.60 44.0 2.62e-01 77.5% 27.9%
3au4A04 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.60 42.0 3.89e-01 74.6% 92.5%
1mixA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.59 43.0 3.97e-01 77.5% 95.7%
4r3dA03 2.60.120.1680 Mainly Beta › Sandwich › Jelly Rolls › 0.59 38.0 3.07e-01 84.5% 33.6%
3pg7A02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.59 45.0 3.97e-01 83.1% 92.7%
3i3tA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.59 40.0 2.67e-01 70.4% 93.4%
5xpyA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.59 41.0 3.61e-01 73.2% 82.4%
1itvA00 2.110.10.10 Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain 0.58 48.0 3.58e-01 94.4% 96.4%
3nvnA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.58 50.0 3.18e-01 97.2% 95.0%
1fblA02 2.110.10.10 Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain 0.58 48.0 3.66e-01 97.2% 98.4%
3x29A00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.57 45.0 3.51e-01 87.3% 80.1%
5chtB00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.57 41.0 2.74e-01 76.1% 92.3%
2bolB02 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.57 41.0 3.34e-01 74.6% 89.8%
4msxA02 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.57 43.0 2.87e-01 81.7% 97.0%
6qk7A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.57 50.0 3.23e-01 98.6% 93.8%
4tyzA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.57 42.0 3.71e-01 80.3% 88.1%
2cn3A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.56 47.0 3.09e-01 93.0% 93.7%
6iikB00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 41.0 2.68e-01 77.5% 93.4%
1shyB01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.56 46.0 2.86e-01 93.0% 96.4%
1e2tA02 3.30.1120.150 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.56 40.0 3.83e-01 76.1% 82.6%
3ihpA03 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 42.0 2.69e-01 78.9% 98.8%
1okeB02 3.30.67.10 Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 0.56 41.0 4.05e-01 83.1% 72.7%
1hxnA00 2.110.10.10 Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain 0.56 46.0 3.43e-01 98.6% 95.7%
5cvmA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.55 40.0 2.73e-01 80.3% 92.2%
4cc9A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.55 43.0 2.86e-01 85.9% 61.9%
1nr0A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.55 43.0 2.86e-01 85.9% 59.7%
2dn6A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.55 41.0 3.60e-01 83.1% 87.8%
1wi5A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 35.0 3.53e-01 74.6% 62.7%
4b8eB00 2.60.120.920 Mainly Beta › Sandwich › Jelly Rolls › SPRY domain 0.54 43.0 3.11e-01 84.5% 51.0%
1dbhA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.54 41.0 3.44e-01 83.1% 85.2%
3fm8D03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.54 37.0 3.29e-01 71.8% 94.4%
4qa8A00 2.50.20.20 Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › 0.54 43.0 3.15e-01 90.1% 77.1%
2i0rA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.53 43.0 2.81e-01 90.1% 94.2%
6epkA02 3.30.67.10 Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 0.53 38.0 3.87e-01 85.9% 78.9%
1w5rA01 3.30.2140.10 Alpha Beta › 2-Layer Sandwich › Arylamine N-acetyltransferase fold › Arylamine N-acetyltransferase 0.52 37.0 2.86e-01 76.1% 42.2%
2bszA01 3.30.2140.10 Alpha Beta › 2-Layer Sandwich › Arylamine N-acetyltransferase fold › Arylamine N-acetyltransferase 0.52 36.0 2.77e-01 73.2% 35.9%
7qu9A01 3.60.120.10 Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase 0.51 39.0 2.42e-01 81.7% 48.5%
4g54A01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.51 42.0 3.55e-01 93.0% 80.8%
1vx7H01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.51 30.0 2.91e-01 73.2% 47.1%
3ei3A02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 44.0 2.89e-01 98.6% 90.5%
3fsdA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 39.0 3.29e-01 83.1% 53.7%
ECOD (77)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4003463 220.1.1.168 beta barrels › PH domain-like › PH domain-like › PH domain-like › Tmpp129 0.66 47.0 3.95e-01 76.1% 80.8%
3934175 220.1.1.168 beta barrels › PH domain-like › PH domain-like › PH domain-like › Tmpp129 0.66 48.0 4.04e-01 77.5% 81.7%
3621723 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.65 48.0 3.32e-01 78.9% 42.4%
3396774 220.1.1.168 beta barrels › PH domain-like › PH domain-like › PH domain-like › Tmpp129 0.65 48.0 4.21e-01 78.9% 94.5%
3509362 220.1.1.160 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_MADD 0.65 45.0 4.17e-01 73.2% 98.9%
5078629 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.64 45.0 3.93e-01 74.6% 93.6%
4960280 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.64 46.0 4.26e-01 78.9% 89.5%
3480502 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.63 43.0 2.52e-01 70.4% 32.5%
3607882 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.63 46.0 3.97e-01 76.1% 94.5%
3756865 220.1.1.170 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_alsin 0.62 47.0 3.83e-01 81.7% 87.1%
3489849 5.1.4.74 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Vps16_N 0.62 43.0 2.61e-01 71.8% 13.5%
3904573 5.1.5.18 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Vps16_N 0.62 49.0 3.10e-01 84.5% 27.4%
3437923 12.1.1.87 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › SWIM 0.62 39.0 4.22e-01 94.4% 76.7%
3597489 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.61 50.0 3.16e-01 90.1% 49.2%
4977715 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 43.0 3.71e-01 74.6% 96.5%
3527277 633.23.1.1 alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin 0.61 50.0 3.72e-01 93.0% 71.8%
3490907 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.61 47.0 2.98e-01 83.1% 92.3%
4950368 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.61 50.0 4.01e-01 95.8% 83.9%
3620049 5.1.4.220 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_2nd 0.61 43.0 2.81e-01 74.6% 25.6%
3237895 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.60 41.0 2.68e-01 70.4% 90.3%
3399742 5.1.4.220 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_2nd 0.60 43.0 2.75e-01 74.6% 24.1%
3615220 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.60 48.0 3.67e-01 90.1% 73.7%
3494259 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.60 44.0 2.72e-01 77.5% 94.7%
3788099 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.60 44.0 2.73e-01 77.5% 92.4%
3358186 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.60 45.0 2.88e-01 80.3% 95.7%
3178434 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.60 44.0 2.78e-01 77.5% 92.6%
3926611 5.1.4.220 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_2nd 0.60 42.0 2.76e-01 74.6% 25.1%
3534783 11.1.1.787 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ITI_HC_C 0.59 48.0 3.38e-01 91.5% 88.6%
4003825 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.59 41.0 2.54e-01 70.4% 93.7%
3382767 219.1.1.112 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH, UCH_1 0.59 45.0 2.94e-01 81.7% 95.5%
2100847 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 42.0 3.75e-01 76.1% 86.7%
4011362 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.59 44.0 2.87e-01 80.3% 64.9%
4022249 5.1.5.4 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DPPIV_N 0.59 46.0 2.79e-01 83.1% 14.9%
4012314 219.1.1.6 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Acetyltransf_2 0.59 43.0 2.87e-01 78.9% 63.7%
3706874 5.1.3.243 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Beta-prop_WDR35_2nd 0.59 41.0 2.72e-01 74.6% 27.6%
3579987 220.1.1.160 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_MADD 0.58 41.0 3.66e-01 76.1% 80.0%
3800852 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.58 44.0 2.79e-01 78.9% 96.8%
3993085 5.1.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 4-bladed › Hemopexin 0.58 46.0 3.39e-01 87.3% 70.8%
3709033 5.1.4.391 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CFAP43_N 0.58 50.0 3.27e-01 94.4% 99.3%
3389668 220.1.1.160 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_MADD 0.58 41.0 3.74e-01 76.1% 92.0%
4235474 4237.1.1.1 beta barrels › FomD-like › FomD-like › FomD-like › DUF402 0.58 44.0 3.43e-01 84.5% 73.2%
3882213 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 41.0 3.84e-01 76.1% 98.9%
5081581 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.57 41.0 2.89e-01 76.1% 50.9%
3816322 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.57 48.0 3.10e-01 93.0% 91.3%
4002646 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 44.0 3.00e-01 83.1% 44.2%
4862662 5.1.4.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N 0.56 46.0 3.01e-01 93.0% 96.1%
3386489 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.56 40.0 3.16e-01 77.5% 64.7%
3502265 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.56 45.0 3.42e-01 91.5% 77.8%
3909523 6129.1.1.0 beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family 0.56 43.0 3.15e-01 84.5% 81.5%
3600457 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.56 40.0 2.66e-01 77.5% 85.6%
3496180 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.56 41.0 3.49e-01 81.7% 75.4%
4561170 5.1.5.4 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DPPIV_N 0.55 45.0 2.72e-01 87.3% 13.8%
3556708 247.1.1.38 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › CPSF73-100_C 0.55 39.0 3.91e-01 93.0% 70.7%
3492330 5.1.4.116 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › IKI3 0.55 44.0 2.80e-01 87.3% 76.5%
3499149 5.1.5.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.55 44.0 2.72e-01 87.3% 65.7%
4019954 5.1.4.169 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RSE1_2nd 0.55 47.0 3.04e-01 98.6% 92.1%
3606041 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.55 42.0 2.81e-01 83.1% 66.6%
3899940 331.4.1.9 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › CPSF73-100_C 0.55 40.0 3.83e-01 93.0% 67.5%
4965483 5.1.5.11 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › PQQ_2 0.54 45.0 2.85e-01 90.1% 79.7%
3903925 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.54 44.0 3.23e-01 87.3% 51.7%
3219185 10.1.1.0 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.54 43.0 3.38e-01 85.9% 62.8%
3694580 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.54 46.0 2.86e-01 93.0% 97.1%
3606753 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.53 44.0 2.76e-01 88.7% 99.7%
3589829 9.4.1.0 beta barrels › Lipocalins/Streptavidin › D-aminopeptidase, middle and C-terminal domains › D-aminopeptidase, middle and C-terminal domains 0.53 41.0 3.67e-01 85.9% 92.4%
3788776 5.1.4.38 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › ANAPC1 0.53 43.0 2.82e-01 91.5% 94.0%
3783065 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.53 41.0 2.64e-01 83.1% 98.9%
3692594 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.52 43.0 2.69e-01 90.1% 95.8%
3595430 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.52 43.0 3.21e-01 94.4% 71.0%
3227356 633.23.1.4 alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_2 0.52 42.0 3.13e-01 94.4% 76.3%
3485620 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.52 42.0 2.64e-01 85.9% 92.2%
3222575 207.1.1.81 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.52 38.0 2.66e-01 78.9% 39.4%
5009920 2004.1.1.308 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 0.52 37.0 2.48e-01 77.5% 25.4%
3227619 6129.1.1.1 beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD 0.52 41.0 3.14e-01 90.1% 81.6%
3436173 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.51 38.0 2.55e-01 81.7% 94.2%
3719044 219.1.1.112 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH, UCH_1 0.51 42.0 2.70e-01 88.7% 86.6%
3890147 633.23.1.33 alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin, GSG-1 0.51 42.0 3.11e-01 95.8% 68.1%
3468148 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.50 37.0 2.81e-01 81.7% 94.4%
D5 medium residues 294-354
PDB
Domain cluster: representative
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xvlA01 2.60.40.1760 Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) 0.71 52.0 3.45e-01 77.0% 72.6%
5f7uA02 2.60.40.1760 Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) 0.69 51.0 3.43e-01 78.7% 71.7%
7ufsA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.67 49.0 3.20e-01 77.0% 96.9%
3witA00 2.20.220.20 Mainly Beta › Single Sheet › Glycosyl hydrolase fold › 0.66 41.0 4.08e-01 77.0% 60.9%
7dd9A02 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.65 48.0 3.22e-01 82.0% 99.6%
2f2hA01 2.60.40.1760 Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) 0.64 51.0 3.38e-01 86.9% 61.2%
3vsmA03 2.60.40.4340 Mainly Beta › Sandwich › Immunoglobulin-like › 0.64 52.0 4.47e-01 100.0% 57.4%
6phxA01 2.70.98.60 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › alpha-galactosidase from lactobacil brevis 0.62 49.0 3.14e-01 86.9% 95.7%
3lxqA01 3.30.1120.80 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.60 52.0 4.36e-01 100.0% 57.6%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 42.0 3.93e-01 73.8% 72.0%
2vxgA02 1.10.220.100 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › conserved c-terminal region of ge- 1 0.60 48.0 4.37e-01 90.2% 92.9%
2g7zA02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.58 41.0 3.40e-01 77.0% 95.0%
1hdhA02 3.30.1120.10 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.58 50.0 4.64e-01 96.7% 83.1%
2m87A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 42.0 3.59e-01 78.7% 93.2%
2jpiA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.58 47.0 3.96e-01 100.0% 55.2%
1xteA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.58 41.0 3.44e-01 78.7% 69.8%
1f49A05 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.57 49.0 3.14e-01 95.1% 44.5%
5mu3B00 3.40.50.12050 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 46.0 3.42e-01 93.4% 68.7%
2vgaA00 2.60.240.10 Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › Major secreted virus protein 0.55 45.0 3.14e-01 90.2% 84.0%
1hxnA00 2.110.10.10 Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain 0.54 46.0 3.26e-01 100.0% 77.6%
1xffA00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.53 43.0 3.00e-01 96.7% 34.5%
1vx7H01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.53 36.0 3.32e-01 91.8% 52.9%
5kckA00 3.60.120.10 Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase 0.53 38.0 2.39e-01 82.0% 12.9%
3d6wB01 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.53 36.0 3.52e-01 75.4% 64.3%
1shyB01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 42.0 2.55e-01 90.2% 28.0%
3igfA02 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 37.0 3.54e-01 77.0% 67.6%
3dzvA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.51 46.0 2.97e-01 100.0% 22.7%
1w5rA01 3.30.2140.10 Alpha Beta › 2-Layer Sandwich › Arylamine N-acetyltransferase fold › Arylamine N-acetyltransferase 0.51 45.0 3.24e-01 100.0% 77.5%
4esnA00 2.60.320.10 Mainly Beta › Sandwich › mini-chromosome maintenance (MCM) complex, domain 2 › N-utilization substance G protein NusG, insert domain 0.50 42.0 3.97e-01 100.0% 82.1%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3219323 207.1.1.81 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.70 51.0 3.33e-01 96.7% 19.6%
5058484 331.1.1.0 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.69 49.0 4.70e-01 93.4% 65.7%
3562895 6129.1.1.1 beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD 0.68 62.0 4.32e-01 100.0% 41.1%
3889534 6129.1.1.1 beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD 0.67 62.0 4.28e-01 100.0% 38.9%
4858307 6129.1.1.1 beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD 0.67 61.0 4.27e-01 100.0% 40.2%
4964626 101.1.2.931 alpha arrays › HTH › HTH › winged helix domain › DUF7528 0.66 50.0 4.01e-01 83.6% 64.6%
5016434 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.66 51.0 4.86e-01 86.9% 100.0%
3748485 6129.1.1.1 beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD 0.66 60.0 4.12e-01 100.0% 37.4%
3416069 331.1.1.0 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.64 43.0 4.11e-01 95.1% 60.0%
3212555 2484.1.1.200 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FTH 0.64 49.0 3.77e-01 96.7% 38.5%
3211176 207.1.1.81 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.64 49.0 3.17e-01 96.7% 19.6%
4937221 331.1.1.0 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.63 45.0 4.26e-01 100.0% 62.7%
3924841 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.63 46.0 3.04e-01 91.8% 19.6%
3213871 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.63 50.0 3.20e-01 91.8% 54.1%
3899940 331.4.1.9 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › CPSF73-100_C 0.62 46.0 4.26e-01 100.0% 61.3%
3386489 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.62 52.0 3.92e-01 100.0% 68.8%
3992656 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.62 54.0 3.67e-01 100.0% 63.0%
4031431 331.1.1.0 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.62 41.0 4.09e-01 88.5% 64.6%
3718216 4051.1.1.0 a+b two layers › a+b domain in Capz › a+b domain in Capz › a+b domain in Capz 0.61 44.0 3.48e-01 77.0% 53.6%
3228574 207.1.1.81 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.60 48.0 3.13e-01 95.1% 20.9%
4234211 3111.1.1.0 beta barrels › STT3/PglB/AglB beta-barrel domain › STT3/PglB/AglB beta-barrel domain › STT3/PglB/AglB beta-barrel domain 0.58 52.0 4.67e-01 98.4% 81.2%
4928397 1.1.9.1 beta barrels › cradle loop barrel › RIFT-related › PUA domain › PUA 0.58 45.0 3.62e-01 85.2% 100.0%
4184601 12.3.1.6 beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Bgal_small_N 0.58 50.0 3.20e-01 95.1% 40.7%
3735087 12.3.1.6 beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Bgal_small_N 0.58 50.0 3.07e-01 95.1% 48.6%
4088781 12.3.1.6 beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Bgal_small_N 0.58 50.0 3.53e-01 95.1% 65.6%
3401010 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 40.0 3.27e-01 73.8% 40.9%
3863194 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.57 41.0 3.28e-01 77.0% 66.9%
4283763 12.3.1.6 beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Bgal_small_N 0.57 49.0 3.16e-01 95.1% 41.2%
4946049 79.1.1.0 beta duplicates or obligate multimers › Phage tail fiber protein trimerization domain › Phage tail fiber protein trimerization domain › Phage tail fiber protein trimerization domain 0.56 50.0 4.59e-01 100.0% 87.5%
5030224 213.1.1.0 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.56 49.0 4.13e-01 100.0% 61.0%
3886774 633.23.1.1 alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin 0.55 44.0 3.24e-01 93.4% 87.9%
3604297 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.55 39.0 2.97e-01 80.3% 41.7%
4957580 10.29.1.0 beta sandwiches › jelly-roll › Jelly-roll domain in distal tail protein (Dit)-like proteins › Jelly-roll domain in distal tail protein (Dit)-like proteins 0.54 43.0 3.35e-01 85.2% 76.2%
3222575 207.1.1.81 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.54 47.0 3.09e-01 96.7% 32.0%
3264116 5.1.5.76 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40, Beta-prop_NOL10_N 0.54 46.0 2.90e-01 100.0% 35.1%
1921563 101.1.2.175 alpha arrays › HTH › HTH › winged helix domain › HTH_57 0.53 42.0 3.50e-01 85.2% 69.2%
4980224 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.53 39.0 3.19e-01 82.0% 83.2%
3783345 5.1.4.21 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Pep3_Vps18 0.53 47.0 3.00e-01 100.0% 29.5%
3209881 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.52 43.0 2.53e-01 96.7% 12.8%
3219961 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.51 36.0 2.97e-01 80.3% 64.4%
4352331 101.1.2.788 alpha arrays › HTH › HTH › winged helix domain › PF29760 0.51 40.0 3.69e-01 100.0% 64.4%
3615220 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.51 40.0 3.07e-01 96.7% 92.0%
5028109 318.1.1.0 a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 0.50 39.0 3.66e-01 96.7% 69.3%
D6 medium residues 366-453
PDB
Domain cluster: representative
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1x9mA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.62 46.0 3.42e-01 78.4% 35.0%
3lm3A02 3.30.1120.110 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.59 40.0 3.80e-01 70.5% 83.2%
3cm1A00 2.30.31.20 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Sporulation-specific cell division protein SsgB 0.59 44.0 3.87e-01 80.7% 81.6%
4bf3A00 2.30.31.50 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Borrelia outer surface protein E/F 0.58 41.0 3.56e-01 72.7% 97.0%
1lfoA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.58 40.0 3.54e-01 71.6% 80.3%
3kvpA00 6.20.140.10 Special › Other non-globular › Immunoglobulin-like › 0.58 28.0 3.62e-01 76.1% 88.4%
2it9A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.57 40.0 3.61e-01 72.7% 98.3%
2fblB00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.57 35.0 3.04e-01 72.7% 37.2%
2kc8A00 3.30.2310.20 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like 0.56 34.0 3.39e-01 90.9% 55.8%
1q67A01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 41.0 3.60e-01 79.5% 89.3%
3dcxA00 2.30.29.50 Mainly Beta › Roll › PH-domain like › Bacterial Pleckstrin homology domain 0.56 42.0 3.85e-01 80.7% 77.8%
2lydA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 42.0 3.65e-01 79.5% 75.4%
3u12A00 2.30.29.180 Mainly Beta › Roll › PH-domain like › Ubiquitin carboxyl-terminal hydrolase 26/29/37, pleckstrin homology-like domain 0.55 41.0 3.96e-01 80.7% 99.0%
2yvkA01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.55 39.0 3.42e-01 76.1% 58.1%
4cy8A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 39.0 2.88e-01 76.1% 46.2%
3fehA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.54 43.0 3.87e-01 86.4% 98.4%
2qzuA02 3.30.1120.10 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.54 40.0 4.10e-01 78.4% 81.2%
1e2tA03 2.40.128.150 Mainly Beta › Beta Barrel › Lipocalin › Cysteine proteinases 0.53 37.0 3.41e-01 71.6% 77.8%
4tm3A00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 38.0 2.50e-01 76.1% 59.7%
1h10A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.53 38.0 3.54e-01 77.3% 86.3%
7ne4A01 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.53 41.0 2.80e-01 84.1% 26.7%
3fewX02 3.30.1310.40 Alpha Beta › 2-Layer Sandwich › Ybab; Chain: A; › 0.53 33.0 3.24e-01 77.3% 56.8%
1gpqB00 3.40.1420.10 Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › Inhibitor of vertebrate lysozyme 0.52 36.0 3.20e-01 70.5% 65.6%
2v73A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.52 41.0 3.30e-01 86.4% 70.5%
5iroD00 2.60.40.3530 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 37.0 3.61e-01 77.3% 92.2%
1ejfA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 38.0 3.60e-01 79.5% 80.0%
2r16A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.51 38.0 3.08e-01 78.4% 62.9%
7t8tA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 38.0 3.38e-01 79.5% 87.0%
1ynjJ02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.50 29.0 3.36e-01 70.5% 80.6%
3sh4A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.50 38.0 3.06e-01 84.1% 76.9%
6vp6A03 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.50 38.0 2.64e-01 83.0% 36.2%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4998507 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.66 37.0 4.56e-01 79.5% 90.7%
3510850 3459.1.1.0 beta sandwiches › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule › Fas apoptotic inhibitory molecule 0.64 44.0 4.44e-01 71.6% 100.0%
5001282 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.64 44.0 3.70e-01 71.6% 90.3%
4229035 2484.1.1.12 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Acetate_kinase 0.63 46.0 3.59e-01 78.4% 59.5%
3616762 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.62 43.0 3.29e-01 71.6% 64.1%
5013176 4100.1.1.0 a+b duplicates or obligate multimers › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like 0.60 42.0 4.52e-01 72.7% 94.7%
4926892 220.1.1.87 beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_3 0.59 44.0 4.10e-01 80.7% 82.6%
185116 295.1.1.2 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › SsgA 0.59 44.0 3.86e-01 80.7% 81.0%
4986577 220.1.1.87 beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_3 0.58 45.0 4.20e-01 84.1% 83.6%
3471615 220.1.1.158 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_LRR1 0.57 43.0 4.00e-01 80.7% 90.4%
5015520 71.1.1.0 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB 0.57 34.0 2.59e-01 71.6% 24.8%
3813657 220.1.1.172 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_PRMT_N 0.57 41.0 3.83e-01 76.1% 91.8%
3482454 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.56 42.0 3.16e-01 78.4% 64.7%
4302400 5.1.7.2 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 10-bladed › Sortilin-Vps10 0.55 42.0 2.60e-01 83.0% 15.0%
1765704 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.55 38.0 2.88e-01 71.6% 54.8%
3585398 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.55 39.0 3.20e-01 75.0% 65.5%
4947901 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.54 33.0 3.33e-01 72.7% 59.1%
3699020 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.54 44.0 3.09e-01 90.9% 73.7%
5014023 71.1.1.0 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB 0.53 41.0 3.20e-01 81.8% 58.7%
4059889 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.53 36.0 3.76e-01 70.5% 87.5%
3955707 4.8.1.0 beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.52 37.0 3.84e-01 75.0% 84.7%
3186839 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.52 40.0 2.70e-01 84.1% 21.9%
4964178 319.1.1.29 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › DUF7127 0.52 31.0 3.37e-01 72.7% 71.2%
5074343 319.1.1.23 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › PF29697 0.51 32.0 3.43e-01 72.7% 73.3%
3259661 331.23.1.9 a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain › RnlA_toxin 0.51 35.0 3.76e-01 70.5% 100.0%
4933539 2484.1.1.302 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.51 35.0 2.71e-01 71.6% 62.3%
3336515 5.1.3.67 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.51 39.0 2.66e-01 81.8% 28.3%
3194130 5.1.5.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.51 39.0 2.58e-01 84.1% 21.3%
3728267 244.1.1.35 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › NAD_binding_8 0.50 34.0 2.91e-01 77.3% 41.9%
3694428 2003.1.2.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.50 39.0 2.53e-01 84.1% 68.8%
4002330 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.50 37.0 2.93e-01 79.5% 51.0%
D7 medium residues 454-511
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.93 70.0 6.88e-01 79.3% 79.0%
4a18O00 3.30.390.110 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.81 63.0 4.71e-01 82.8% 79.9%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 64.0 4.59e-01 89.7% 47.5%
2ly8A00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.67 48.0 3.76e-01 75.9% 45.5%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4270964 109.4.1.2789 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29386, PF29407 0.90 66.0 3.73e-01 82.8% 8.0%
4649114 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.74 59.0 4.89e-01 86.2% 52.0%
3858340 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.70 50.0 3.83e-01 77.6% 33.6%