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IMGVR_UViG_3300010351_001766-3300010351-Ga0116248_100044545
Arc-VirIMGVR_UViG_3300010351_001766-3300010351-Ga0116248_100044545
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-227_319-384
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02739.23 best | 5_3_exonuc_N | 50.4 | 2.90e-13 | 61.3% | 84.8% |
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1xo1A02 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.84 | 46.0 | 6.30e-01 | 84.2% | 99.4% |
| 1tfrA01 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.83 | 56.0 | 6.73e-01 | 96.2% | 97.1% |
| 5hsgA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.60 | 26.0 | 4.06e-01 | 76.0% | 97.6% |
| 1ba2A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 26.0 | 3.95e-01 | 76.0% | 97.6% |
| 1a6dA03 | 3.50.7.10 | Alpha Beta › 3-Layer(bba) Sandwich › GroEL › GroEL | 0.58 | 27.0 | 3.68e-01 | 84.6% | 83.0% |
| 4ry8A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 26.0 | 3.68e-01 | 75.7% | 85.1% |
| 2vk2A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 26.0 | 3.90e-01 | 76.4% | 96.2% |
| 3l49A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 26.0 | 3.91e-01 | 75.0% | 97.7% |
| 2hqbA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 25.0 | 3.76e-01 | 76.7% | 92.4% |
| 4rxmA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 26.0 | 3.77e-01 | 75.7% | 95.3% |
| 4y9tA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 28.0 | 3.91e-01 | 77.4% | 95.2% |
| 4ru1A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 27.0 | 3.82e-01 | 76.0% | 94.3% |
| 3kl2F00 | 3.40.50.850 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like | 0.55 | 37.0 | 4.30e-01 | 87.0% | 96.0% |
| 4xxhA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 26.0 | 3.84e-01 | 99.0% | 97.1% |
| 3brsA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 26.0 | 3.81e-01 | 75.7% | 97.1% |
| 1dbqA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 25.0 | 3.68e-01 | 76.4% | 94.0% |
| 1yb5A02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 29.0 | 3.71e-01 | 89.7% | 87.5% |
| 3bblA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 26.0 | 3.78e-01 | 100.0% | 98.6% |
| 1mdbA01 | 3.40.50.980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 26.0 | 3.46e-01 | 82.2% | 83.5% |
| 3rotA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 27.0 | 3.74e-01 | 87.7% | 100.0% |
| 2qtlA03 | 3.40.50.80 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module | 0.53 | 29.0 | 3.85e-01 | 76.4% | 97.4% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4995752 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.87 | 48.0 | 6.54e-01 | 77.4% | 97.6% |
| 2074443 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.87 | 48.0 | 6.35e-01 | 77.1% | 92.5% |
| 3969358 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.87 | 48.0 | 6.57e-01 | 77.1% | 99.4% |
| 4125023 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.86 | 49.0 | 6.46e-01 | 77.4% | 95.9% |
| 3964138 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.86 | 53.0 | 6.86e-01 | 84.9% | 100.0% |
| 3261281 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.86 | 49.0 | 6.56e-01 | 77.4% | 98.8% |
| 4040391 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.85 | 51.0 | 6.58e-01 | 77.4% | 97.2% |
| 3838776 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.85 | 46.0 | 6.28e-01 | 77.4% | 95.8% |
| 4322588 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.85 | 52.0 | 6.74e-01 | 84.2% | 100.0% |
| 3942272 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.85 | 49.0 | 6.55e-01 | 77.4% | 99.4% |
| 4031817 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.85 | 48.0 | 6.36e-01 | 77.4% | 96.5% |
| 4324598 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.84 | 50.0 | 6.38e-01 | 85.6% | 94.1% |
| 4157264 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.84 | 50.0 | 6.50e-01 | 77.4% | 97.8% |
| 3387660 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.83 | 48.0 | 6.30e-01 | 77.4% | 98.2% |
| 3838580 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.79 | 47.0 | 6.01e-01 | 79.8% | 95.6% |
| 5000538 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.77 | 35.0 | 5.29e-01 | 75.7% | 97.0% |
| 3238117 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.73 | 43.0 | 5.28e-01 | 77.1% | 87.7% |
| 4965307 | 2008.1.1.7 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ERCC4 | 0.62 | 26.0 | 3.43e-01 | 87.3% | 66.7% |
| 3987929 | 2007.1.2.10 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_3 | 0.58 | 26.0 | 3.69e-01 | 77.1% | 85.7% |
| 3832178 | 2006.1.4.7 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN_YacP | 0.57 | 33.0 | 4.10e-01 | 88.0% | 88.1% |
| 3601450 | 7524.1.1.0 ↗ | a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like | 0.56 | 22.0 | 2.82e-01 | 82.9% | 59.0% |
| 3660261 | 2006.1.4.7 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN_YacP | 0.55 | 33.0 | 4.22e-01 | 94.9% | 98.3% |
| 5077950 | 2007.1.11.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › L-fucose isomerase, N-terminal and second domains › Fucose_iso_N1 | 0.55 | 27.0 | 3.66e-01 | 76.0% | 90.3% |
| 3478669 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.54 | 29.0 | 3.96e-01 | 99.0% | 98.1% |
| 3291241 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.54 | 29.0 | 3.91e-01 | 75.0% | 98.7% |
| 4326894 | 7512.1.1.10 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_28 | 0.51 | 29.0 | 3.66e-01 | 96.6% | 90.9% |
D2
high
residues 228-315
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ksvA00 | 3.10.620.30 | Alpha Beta › Roll › C8orf32 fold › | 0.58 | 41.0 | 3.26e-01 | 73.9% | 66.5% |
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.58 | 41.0 | 4.46e-01 | 81.8% | 97.0% |
| 4bc3A02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.52 | 39.0 | 3.03e-01 | 79.5% | 82.2% |
| 4ga4A02 | 3.40.1030.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 › Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0.50 | 43.0 | 3.14e-01 | 97.7% | 51.7% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5019623 | 102.1.1.27 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_5 | 0.71 | 50.0 | 5.65e-01 | 98.9% | 100.0% |
| 3501398 | 102.5.1.0 ↗ | alpha arrays › HhH/H2TH › SAM-like subdomain in Sec63-like proteins › SAM-like subdomain in Sec63-like proteins | 0.63 | 45.0 | 4.94e-01 | 97.7% | 94.3% |
| 4080847 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.61 | 45.0 | 4.95e-01 | 94.3% | 100.0% |
| 4644692 | 4953.2.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › Lid-like insertion of Propionyl-CoA synthase (PCS) ligase domain › Lid-like insertion of Propionyl-CoA synthase (PCS) ligase domain | 0.57 | 46.0 | 4.67e-01 | 100.0% | 94.1% |
| 4965582 | 4953.2.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › Lid-like insertion of Propionyl-CoA synthase (PCS) ligase domain › Lid-like insertion of Propionyl-CoA synthase (PCS) ligase domain | 0.55 | 47.0 | 4.68e-01 | 97.7% | 98.9% |
| 3587241 | 3950.1.1.1 ↗ | alpha complex topology › Bacterial vitamin C transporter UlaA/SgaT › Bacterial vitamin C transporter UlaA/SgaT › Bacterial vitamin C transporter UlaA/SgaT › EIIC-GAT | 0.55 | 41.0 | 2.61e-01 | 80.7% | 33.9% |
| 4009282 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.55 | 36.0 | 3.79e-01 | 79.5% | 77.3% |
| 3960168 | 802.1.1.1 ↗ | a+b two layers › Hypothetical protein TM0160 › Hypothetical protein TM0160 › Hypothetical protein TM0160 › BFN_dom | 0.55 | 28.0 | 3.37e-01 | 100.0% | 80.0% |
| 3220832 | 592.7.1.1 ↗ | alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain › GIPC1_GH2 | 0.54 | 40.0 | 4.05e-01 | 100.0% | 78.9% |
| 5057417 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 44.0 | 4.55e-01 | 98.9% | 92.8% |
| 5071947 | 604.39.1.3 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF-ribofla_trS | 0.53 | 46.0 | 3.69e-01 | 98.9% | 96.7% |
| 3781733 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.52 | 45.0 | 4.06e-01 | 100.0% | 95.2% |
| 3622106 | 109.4.1.162 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nup192 | 0.52 | 45.0 | 2.48e-01 | 97.7% | 7.2% |
| 4933326 | 101.1.2.70 ↗ | alpha arrays › HTH › HTH › winged helix domain › PqqD | 0.51 | 41.0 | 4.10e-01 | 98.9% | 86.4% |
| 3517172 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 37.0 | 2.50e-01 | 77.3% | 33.2% |
| 4023956 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.51 | 37.0 | 3.38e-01 | 80.7% | 83.1% |
| 3498627 | 7015.1.1.1 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC | 0.50 | 41.0 | 3.07e-01 | 93.2% | 80.4% |