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IMGVR_UViG_3300013426_000003-3300013426-Ga0116649_100004336
Arc-VirIMGVR_UViG_3300013426_000003-3300013426-Ga0116649_100004336
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 45-162
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.75 | 60.0 | 5.90e-01 | 97.5% | 80.6% |
| 1rp3A01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.72 | 50.0 | 5.74e-01 | 94.9% | 98.8% |
| 1gakA00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.69 | 57.0 | 5.46e-01 | 98.3% | 76.6% |
| 3h4cA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.64 | 38.0 | 4.13e-01 | 89.8% | 69.8% |
| 1u84A00 | 1.10.340.20 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Apc36109-like domain | 0.64 | 33.0 | 3.93e-01 | 89.8% | 72.8% |
| 1sg7A00 | 1.10.1740.70 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB | 0.64 | 40.0 | 4.86e-01 | 86.4% | 100.0% |
| 4k5yA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 47.0 | 3.70e-01 | 89.8% | 38.7% |
| 5tgzA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 50.0 | 3.73e-01 | 89.8% | 65.4% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.59 | 41.0 | 4.50e-01 | 90.7% | 88.4% |
| 1gzmA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 50.0 | 3.65e-01 | 93.2% | 59.5% |
| 6todA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 46.0 | 3.40e-01 | 85.6% | 36.9% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 46.0 | 3.53e-01 | 87.3% | 37.1% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 39.0 | 4.15e-01 | 88.1% | 80.4% |
| 4oh3A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.55 | 50.0 | 3.27e-01 | 100.0% | 22.9% |
| 2jrmA00 | 1.10.10.620 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › ribosome modulation factor like domain | 0.55 | 28.0 | 3.63e-01 | 97.5% | 93.3% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.55 | 46.0 | 4.04e-01 | 90.7% | 93.1% |
| 1gvfB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.54 | 43.0 | 3.29e-01 | 85.6% | 89.5% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.54 | 31.0 | 2.88e-01 | 78.0% | 42.2% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 40.0 | 4.28e-01 | 90.7% | 89.3% |
| 8d3mA02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.53 | 47.0 | 3.80e-01 | 99.2% | 60.4% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 41.0 | 3.82e-01 | 89.8% | 66.2% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 39.0 | 3.65e-01 | 89.8% | 62.2% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 44.0 | 3.66e-01 | 90.7% | 97.7% |
| 1xl3C00 | 1.20.1280.80 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.52 | 33.0 | 3.67e-01 | 91.5% | 81.3% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 38.0 | 3.64e-01 | 87.3% | 65.7% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 40.0 | 3.49e-01 | 100.0% | 52.4% |
| 1nu7D01 | 1.20.120.750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle domain 1 | 0.50 | 37.0 | 3.63e-01 | 79.7% | 71.9% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.50 | 35.0 | 3.65e-01 | 95.8% | 76.4% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.50 | 37.0 | 4.03e-01 | 99.2% | 93.8% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.50 | 38.0 | 3.84e-01 | 93.2% | 79.5% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3973355 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.74 | 45.0 | 5.18e-01 | 94.1% | 83.5% |
| 3588371 | 148.1.3.278 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Bac_RepA_C | 0.68 | 50.0 | 4.98e-01 | 98.3% | 72.8% |
| 4964919 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.68 | 47.0 | 4.06e-01 | 71.2% | 83.2% |
| 3164721 | 1078.1.1.0 ↗ | extended segments › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit | 0.67 | 46.0 | 5.08e-01 | 77.1% | 91.1% |
| 3191794 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.64 | 59.0 | 4.58e-01 | 100.0% | 78.0% |
| 5054041 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 47.0 | 4.09e-01 | 100.0% | 54.1% |
| 3190607 | 6169.1.1.59 ↗ | extended segments › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › PLAC8 | 0.60 | 27.0 | 3.18e-01 | 85.6% | 56.5% |
| 3367788 | 5050.1.1.28 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 | 0.60 | 49.0 | 3.88e-01 | 100.0% | 44.3% |
| 3940867 | 632.22.1.67 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › DUF842 | 0.60 | 46.0 | 5.01e-01 | 85.6% | 100.0% |
| 3924614 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.59 | 53.0 | 4.33e-01 | 100.0% | 53.8% |
| 3283999 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.59 | 48.0 | 5.09e-01 | 99.2% | 98.1% |
| 3285853 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.58 | 42.0 | 4.38e-01 | 90.7% | 81.8% |
| 5059074 | 5076.2.1.18 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF6159 | 0.58 | 52.0 | 4.19e-01 | 97.5% | 79.1% |
| 4960441 | 5076.2.1.18 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF6159 | 0.57 | 51.0 | 4.07e-01 | 100.0% | 78.8% |
| 3281699 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.57 | 42.0 | 3.46e-01 | 100.0% | 42.8% |
| 3619687 | 604.1.1.127 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4 | 0.57 | 35.0 | 3.67e-01 | 76.3% | 66.4% |
| 4376603 | 605.1.1.191 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › NtrY_N | 0.56 | 38.0 | 3.67e-01 | 76.3% | 61.5% |
| 4675001 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 41.0 | 3.43e-01 | 77.1% | 82.9% |
| 3794102 | 5067.1.1.5 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing | 0.55 | 49.0 | 4.19e-01 | 95.8% | 63.2% |
| 4927762 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.54 | 45.0 | 3.20e-01 | 90.7% | 38.7% |
| 4954473 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.54 | 48.0 | 3.75e-01 | 97.5% | 51.4% |
| 4632127 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.54 | 38.0 | 4.31e-01 | 88.1% | 100.0% |
| 4962910 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.53 | 42.0 | 4.11e-01 | 88.1% | 94.1% |
| 3385850 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.52 | 45.0 | 3.61e-01 | 94.9% | 79.4% |
| 4339416 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.52 | 36.0 | 4.10e-01 | 96.6% | 94.4% |
| 3593265 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 46.0 | 3.67e-01 | 100.0% | 72.8% |
| 3193079 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.52 | 47.0 | 4.03e-01 | 100.0% | 69.5% |
| 3223113 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 47.0 | 3.59e-01 | 98.3% | 67.5% |
| 4554416 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.52 | 37.0 | 4.12e-01 | 90.7% | 96.7% |
| 4015041 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.52 | 40.0 | 3.45e-01 | 80.5% | 86.7% |
| 5064592 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.52 | 48.0 | 4.37e-01 | 99.2% | 96.0% |
| 5048320 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.51 | 45.0 | 3.64e-01 | 96.6% | 87.0% |
| 3629137 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.51 | 45.0 | 3.74e-01 | 94.9% | 75.1% |
| 3450966 | 633.22.1.0 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) | 0.51 | 39.0 | 3.50e-01 | 80.5% | 90.3% |
| 4931294 | 5076.2.1.13 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF7847 | 0.51 | 47.0 | 3.65e-01 | 100.0% | 55.1% |