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IMGVR_UViG_3300014491_000362-3300014491-Ga0182014_100193425

Arc-Vir

IMGVR_UViG_3300014491_000362-3300014491-Ga0182014_100193425

Quality

82.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 19-98
PDB
D2 high residues 116-194
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF22763.2 best NrS1-1_pol-like_HBD 52.6 4.40e-14 60.8% 67.2%
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h20A04 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.70 60.0 5.79e-01 100.0% 83.1%
7wu8B01 1.20.1160.20 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › 0.63 52.0 5.21e-01 98.7% 93.7%
3fefA00 3.90.1820.10 Alpha Beta › Alpha-Beta Complex › LDH C-terminal domain-like › AglA-like glucosidase 0.62 45.0 2.81e-01 75.9% 78.1%
1vkeB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.59 48.0 4.48e-01 93.7% 71.3%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 49.0 4.15e-01 100.0% 77.9%
4dllB02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.56 39.0 3.37e-01 73.4% 79.2%
2dkwA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.56 43.0 3.64e-01 82.3% 64.1%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 46.0 3.93e-01 100.0% 76.1%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 46.0 3.86e-01 100.0% 74.5%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 44.0 3.69e-01 100.0% 73.9%
4uqxA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 40.0 3.86e-01 87.3% 73.0%
3pasA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 44.0 3.45e-01 100.0% 55.3%
8hixR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 42.0 2.95e-01 93.7% 57.7%
2ibdA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 42.0 3.59e-01 100.0% 81.0%
4he8D00 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.51 37.0 2.96e-01 87.3% 38.1%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.50 37.0 3.47e-01 78.5% 68.0%
6ko8A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 43.0 3.39e-01 100.0% 58.4%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4962599 6035.1.1.3 alpha bundles › Primase helical domain › Primase helical domain › Primase helical domain › NrS1-1_pol-like_HBD 0.98 95.0 8.78e-01 100.0% 92.6%
4931982 6035.1.1.3 alpha bundles › Primase helical domain › Primase helical domain › Primase helical domain › NrS1-1_pol-like_HBD 0.90 84.0 8.38e-01 97.5% 97.5%
5039859 6035.1.1.0 alpha bundles › Primase helical domain › Primase helical domain › Primase helical domain 0.79 71.0 6.86e-01 100.0% 88.9%
5077614 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.71 61.0 6.23e-01 100.0% 98.7%
4108750 3651.1.1.1 alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B 0.61 48.0 4.21e-01 86.1% 81.7%
4071151 3651.1.1.0 alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain 0.60 47.0 4.09e-01 87.3% 76.2%
3278306 101.1.1.31 alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 0.60 47.0 3.76e-01 87.3% 87.6%
5057633 3651.1.1.0 alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain 0.58 44.0 4.04e-01 86.1% 65.2%
3424390 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 45.0 3.85e-01 100.0% 52.6%
5051432 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.56 49.0 3.51e-01 98.7% 38.7%
3745013 101.1.10.12 alpha arrays › HTH › HTH › Cyclin-like › Spy1 0.54 42.0 3.55e-01 87.3% 97.9%
3301230 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.52 36.0 2.93e-01 89.9% 34.5%
3837477 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.52 37.0 3.52e-01 91.1% 61.0%
3329355 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.51 36.0 3.08e-01 78.5% 42.9%
D3 medium residues 233-322_402-476
PDB
D4 medium residues 323-401
PDB
D5 medium residues 477-565
PDB
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2v6zM00 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.78 48.0 5.23e-01 79.8% 74.7%
7wd3A04 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.76 51.0 5.44e-01 88.8% 78.2%
4jd9G00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.69 52.0 4.73e-01 87.6% 60.0%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.69 60.0 4.81e-01 100.0% 56.2%
4gx0A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 48.0 4.58e-01 73.0% 90.3%
1jvmB00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 46.0 4.44e-01 70.8% 88.0%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 53.0 4.80e-01 84.3% 70.9%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.65 53.0 5.53e-01 89.9% 98.8%
4y0bA00 1.10.1780.10 Mainly Alpha › Orthogonal Bundle › Double Clp-N motif › Clp, N-terminal domain 0.65 51.0 4.42e-01 85.4% 82.1%
3sykA02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.65 46.0 4.61e-01 93.3% 73.3%
2xq2A01 1.20.1730.10 Mainly Alpha › Up-down Bundle › Sodium/glucose cotransporter › Sodium/glucose cotransporter 0.64 53.0 3.29e-01 92.1% 65.4%
4nlbA02 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.64 44.0 4.37e-01 88.8% 67.0%
6wxrA01 1.10.640.10 Mainly Alpha › Orthogonal Bundle › Myeloperoxidase, subunit C › Haem peroxidase domain superfamily, animal type 0.63 55.0 3.50e-01 96.6% 63.5%
2qksA01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 43.0 4.11e-01 70.8% 89.6%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.63 46.0 4.43e-01 88.8% 67.0%
2eb1C00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.63 52.0 4.28e-01 92.1% 82.8%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 50.0 4.40e-01 86.5% 64.6%
1xfiA02 1.20.1700.10 Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like 0.62 50.0 5.05e-01 88.8% 87.8%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 47.0 4.34e-01 83.1% 70.9%
4lp8A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 43.0 4.08e-01 73.0% 89.4%
1e94E03 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 48.0 4.53e-01 88.8% 69.8%
2c42A06 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.61 39.0 2.55e-01 84.3% 14.8%
4cbeA00 1.20.120.1640 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.61 52.0 3.98e-01 95.5% 47.4%
3d8bB02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 43.0 4.42e-01 84.3% 80.5%
6qumA04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.60 46.0 3.97e-01 93.3% 50.3%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.60 44.0 4.50e-01 93.3% 80.2%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 47.0 4.24e-01 86.5% 70.2%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 50.0 3.90e-01 95.5% 87.6%
1xl7A01 1.10.275.20 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Choline/Carnitine o-acyltransferase 0.58 43.0 4.17e-01 80.9% 80.6%
4dtdA02 1.10.3680.20 Mainly Alpha › Orthogonal Bundle › TerB-like › Actin cross-linking domain 0.57 41.0 3.60e-01 76.4% 92.7%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 46.0 3.77e-01 92.1% 73.7%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 46.0 4.11e-01 93.3% 69.4%
3ctwB00 1.10.8.930 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 0.56 41.0 3.76e-01 78.7% 70.8%
1tfkB00 1.20.120.650 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Colicin D 0.56 39.0 4.04e-01 86.5% 77.9%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.56 43.0 4.05e-01 88.8% 68.5%
4lqxA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.55 47.0 3.32e-01 96.6% 76.6%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 43.0 3.33e-01 85.4% 43.3%
1e91A00 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.55 37.0 3.81e-01 78.7% 72.9%
6fakA02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.54 41.0 4.26e-01 96.6% 93.8%
1z72A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.53 42.0 3.21e-01 86.5% 61.1%
2q8pA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.52 37.0 3.07e-01 75.3% 91.9%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.52 46.0 4.44e-01 98.9% 98.1%
1aorA02 1.10.569.10 Mainly Alpha › Orthogonal Bundle › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A; domain 2 › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2 0.52 43.0 3.40e-01 91.0% 76.9%
1gu9C00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.51 39.0 3.20e-01 80.9% 60.1%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 38.0 3.30e-01 79.8% 71.4%
ECOD (60)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3391392 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.80 54.0 5.68e-01 86.5% 77.5%
5002766 148.1.3.413 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PF30665 0.79 48.0 5.27e-01 78.7% 73.3%
5082057 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.79 51.0 3.35e-01 85.4% 16.4%
4970089 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.78 51.0 4.95e-01 85.4% 60.0%
3706160 148.1.3.19 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 0.76 53.0 5.32e-01 92.1% 71.1%
4198250 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.73 55.0 6.04e-01 93.3% 100.0%
3591364 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.73 51.0 5.11e-01 86.5% 71.1%
3404120 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.72 52.0 4.35e-01 74.2% 64.8%
4967963 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.72 53.0 5.41e-01 88.8% 80.0%
5074726 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.71 47.0 4.83e-01 82.0% 70.6%
3968786 7516.1.1.102 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2, Glyco_trans_2_3 0.70 60.0 3.64e-01 98.9% 14.6%
3202823 3355.1.1.2 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS 0.70 62.0 3.89e-01 98.9% 79.1%
3802467 148.1.3.207 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF7751 0.69 49.0 5.13e-01 84.3% 81.2%
4101262 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.69 48.0 4.81e-01 85.4% 71.1%
3691623 148.1.3.212 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_13 0.69 54.0 5.31e-01 93.3% 78.9%
3226591 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.68 49.0 4.20e-01 75.3% 69.3%
1758759 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.68 48.0 3.53e-01 73.0% 43.1%
4989621 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.68 46.0 4.87e-01 88.8% 78.8%
5064803 607.1.1.1 alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PEP-utilisers_N 0.65 49.0 4.40e-01 79.8% 73.6%
3972080 4953.1.1.29 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › DUF1631 0.65 56.0 4.60e-01 98.9% 56.6%
3880738 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.64 51.0 4.34e-01 84.3% 60.7%
3228384 544.1.1.0 alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 0.64 50.0 4.66e-01 85.4% 92.9%
3969140 607.1.1.1 alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PEP-utilisers_N 0.63 49.0 4.40e-01 82.0% 79.2%
5023625 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.63 43.0 4.21e-01 71.9% 83.0%
1878970 103.2.1.2 alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.63 51.0 4.94e-01 91.0% 79.6%
3989928 148.1.3.197 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Transgly_assoc 0.62 47.0 5.05e-01 86.5% 97.3%
3269745 3350.1.1.1 alpha bundles › Peroxisomal biogenesis factor 3 › Peroxisomal biogenesis factor 3 › Peroxisomal biogenesis factor 3 › Peroxin-3 0.62 53.0 3.70e-01 97.8% 42.2%
3590119 4275.1.1.0 alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like 0.61 43.0 4.38e-01 86.5% 73.3%
3965610 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.61 47.0 4.82e-01 83.1% 89.4%
3933280 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.61 49.0 3.82e-01 86.5% 43.1%
4021619 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.61 46.0 3.11e-01 79.8% 36.4%
3574876 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.61 46.0 4.08e-01 82.0% 65.9%
3323926 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.60 50.0 4.83e-01 93.3% 96.0%
3931312 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.60 49.0 4.42e-01 87.6% 73.3%
4969650 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.60 53.0 3.79e-01 100.0% 64.3%
4976283 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.59 44.0 4.05e-01 78.7% 82.6%
3207585 142.3.1.1 alpha complex topology › Sigma2 domain-like › Mitochondrial morphogenesis protein Sld7 C-terminal domain › Mitochondrial morphogenesis protein Sld7 C-terminal domain › Sld7_C 0.59 48.0 4.98e-01 89.9% 100.0%
4937380 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.59 44.0 4.77e-01 80.9% 98.7%
3187781 109.23.1.7 alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 › TB2_DP1_HVA22 0.59 46.0 4.47e-01 86.5% 79.0%
3622690 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.58 43.0 4.33e-01 78.7% 78.9%
3861849 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.58 51.0 3.50e-01 100.0% 98.8%
3511230 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.58 43.0 4.22e-01 78.7% 74.7%
3498944 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.57 50.0 4.16e-01 96.6% 62.6%
5036993 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.57 44.0 4.45e-01 85.4% 88.9%
5077964 3355.1.1.41 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF401 0.56 50.0 3.27e-01 96.6% 69.5%
5057227 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.56 45.0 4.02e-01 87.6% 90.8%
4931294 5076.2.1.13 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF7847 0.56 50.0 3.65e-01 100.0% 45.3%
3592977 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.56 47.0 4.11e-01 94.4% 67.4%
3990104 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.56 42.0 3.10e-01 80.9% 35.3%
3389416 140.1.1.0 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.56 41.0 3.98e-01 78.7% 70.0%
3381284 5059.1.1.33 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, SLC35F 0.56 42.0 2.88e-01 80.9% 49.5%
5065764 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.55 42.0 4.01e-01 83.1% 69.5%
3586872 142.1.1.26 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Transgly_assoc 0.54 45.0 4.70e-01 95.5% 100.0%
3797551 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.54 49.0 3.39e-01 100.0% 85.2%
3632799 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.54 41.0 3.65e-01 83.1% 71.9%
3581438 4291.1.1.1 beta barrels › Oxysterol-binding protein › Oxysterol-binding protein › Oxysterol-binding protein › Oxysterol_BP 0.54 45.0 3.01e-01 93.3% 55.9%
3895470 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.53 39.0 3.88e-01 79.8% 75.8%
3314927 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.52 46.0 3.80e-01 98.9% 85.5%
4981193 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.51 44.0 3.28e-01 100.0% 76.9%
3971935 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.51 40.0 3.75e-01 84.3% 71.8%