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IMGVR_UViG_3300014555_000025-3300014555-Ga0134422_10068824
Arc-VirIMGVR_UViG_3300014555_000025-3300014555-Ga0134422_10068824
Identity
- Kingdom:
- archaea
Quality
90.0
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-65
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF24132.2 best | DUF7399 | 28.3 | 3.00e-06 | 96.9% | 44.8% |
CATH (56)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2giaA00 | 2.30.31.40 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › | 0.70 | 56.0 | 4.27e-01 | 89.1% | 70.8% |
| 3k44B00 | 3.30.2450.30 | Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › | 0.69 | 53.0 | 4.10e-01 | 82.8% | 77.1% |
| 2giaB00 | 2.30.31.40 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › | 0.64 | 50.0 | 3.88e-01 | 85.9% | 76.7% |
| 2it9A00 | 2.30.31.10 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A | 0.63 | 49.0 | 3.98e-01 | 84.4% | 85.8% |
| 2xzhA00 | 2.130.10.110 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Clathrin heavy-chain terminal domain | 0.61 | 45.0 | 2.87e-01 | 79.7% | 19.8% |
| 2gfgA00 | 2.40.320.10 | Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 | 0.60 | 51.0 | 3.72e-01 | 100.0% | 45.0% |
| 1viuC00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.59 | 42.0 | 3.08e-01 | 75.0% | 70.7% |
| 3wasA00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.59 | 47.0 | 2.99e-01 | 92.2% | 27.2% |
| 2qm4A01 | 2.170.210.10 | Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › DNA double-strand break repair and VJ recombination XRCC4, N-terminal | 0.59 | 47.0 | 3.74e-01 | 90.6% | 80.4% |
| 5fgoA00 | 3.10.450.700 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.58 | 45.0 | 4.55e-01 | 92.2% | 87.1% |
| 1zc3B00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.58 | 48.0 | 4.17e-01 | 98.4% | 82.6% |
| 3h6qA00 | 2.80.10.50 | Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › | 0.57 | 47.0 | 3.63e-01 | 98.4% | 97.6% |
| 4htgA03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.57 | 47.0 | 4.42e-01 | 93.8% | 83.5% |
| 2nwvA00 | 3.30.310.110 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › XisI-like | 0.57 | 45.0 | 3.86e-01 | 90.6% | 71.4% |
| 6j8yA00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.57 | 48.0 | 3.31e-01 | 100.0% | 36.6% |
| 6w5yC01 | 3.90.310.10 | Alpha Beta › Alpha-Beta Complex › Viral Glycoprotein Gp70 › ENV polyprotein, receptor-binding domain | 0.57 | 40.0 | 3.17e-01 | 76.6% | 100.0% |
| 2nvmA00 | 3.30.310.110 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › XisI-like | 0.56 | 45.0 | 3.89e-01 | 90.6% | 69.2% |
| 2xrnA02 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.56 | 41.0 | 3.07e-01 | 81.2% | 75.1% |
| 2cm4A00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.56 | 46.0 | 3.71e-01 | 100.0% | 66.9% |
| 3ulbA01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.55 | 44.0 | 4.17e-01 | 93.8% | 89.2% |
| 2a22B00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.55 | 42.0 | 2.99e-01 | 84.4% | 81.3% |
| 4ydzA00 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.55 | 45.0 | 3.59e-01 | 92.2% | 90.4% |
| 3f2bA01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.55 | 38.0 | 3.36e-01 | 79.7% | 47.9% |
| 8d7eC01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.55 | 38.0 | 3.55e-01 | 75.0% | 100.0% |
| 2fggA01 | 3.30.160.240 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Rv1738 | 0.54 | 38.0 | 3.63e-01 | 75.0% | 61.3% |
| 5gvcB01 | 3.40.50.140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 36.0 | 2.75e-01 | 70.3% | 27.0% |
| 1ah5A03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.54 | 44.0 | 4.04e-01 | 92.2% | 76.7% |
| 2ar5A00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.54 | 42.0 | 3.56e-01 | 89.1% | 76.1% |
| 6m9yA00 | 3.30.1300.40 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.53 | 30.0 | 3.15e-01 | 92.2% | 57.9% |
| 1epaA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.53 | 42.0 | 3.28e-01 | 92.2% | 95.6% |
| 1m2xA00 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.53 | 37.0 | 2.68e-01 | 76.6% | 27.4% |
| 3jtzA00 | 3.30.160.390 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Integrase, DNA-binding domain | 0.53 | 36.0 | 3.53e-01 | 93.8% | 62.3% |
| 2kc8A00 | 3.30.2310.20 | Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like | 0.53 | 37.0 | 3.41e-01 | 89.1% | 52.6% |
| 4aghA00 | 2.30.31.10 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A | 0.53 | 45.0 | 4.15e-01 | 92.2% | 82.5% |
| 3qkgA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.53 | 43.0 | 3.39e-01 | 98.4% | 55.5% |
| 1u7bA00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.53 | 44.0 | 3.08e-01 | 100.0% | 37.1% |
| 3apuB00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.52 | 44.0 | 3.32e-01 | 98.4% | 64.5% |
| 1tu1A00 | 3.40.1000.10 | Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich | 0.52 | 42.0 | 3.29e-01 | 92.2% | 42.4% |
| 1xeuA02 | 2.60.40.1220 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 38.0 | 3.52e-01 | 79.7% | 84.3% |
| 3oh8A01 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.51 | 40.0 | 3.24e-01 | 90.6% | 80.7% |
| 4fb5A02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.51 | 43.0 | 2.98e-01 | 96.9% | 93.8% |
| 1imuA00 | 3.30.160.100 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like | 0.51 | 39.0 | 3.37e-01 | 84.4% | 57.9% |
| 2hv2A01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.51 | 36.0 | 3.28e-01 | 76.6% | 77.9% |
| 4m7xA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.51 | 37.0 | 3.38e-01 | 79.7% | 72.5% |
| 3p0cA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.51 | 41.0 | 3.49e-01 | 90.6% | 78.4% |
| 2v73A00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.51 | 41.0 | 3.03e-01 | 90.6% | 79.8% |
| 1v1cA00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.51 | 42.0 | 4.14e-01 | 100.0% | 92.6% |
| 4ckbD03 | 2.40.50.830 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.51 | 38.0 | 3.15e-01 | 85.9% | 59.7% |
| 3htyA00 | 2.40.128.280 | Mainly Beta › Beta Barrel › Lipocalin › | 0.51 | 41.0 | 3.77e-01 | 98.4% | 96.8% |
| 2k4vA00 | 3.30.160.370 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 | 0.51 | 44.0 | 3.60e-01 | 100.0% | 79.2% |
| 3p3yA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 35.0 | 3.18e-01 | 73.4% | 82.2% |
| 4wfvA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.51 | 41.0 | 3.27e-01 | 98.4% | 69.3% |
| 2zfdB00 | 3.30.310.80 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 | 0.51 | 34.0 | 2.87e-01 | 70.3% | 71.6% |
| 2hqlA01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.50 | 37.0 | 3.39e-01 | 82.8% | 59.3% |
| 3a57A00 | 2.60.270.30 | Mainly Beta › Sandwich › Mutm (Fpg) Protein; Chain: A, domain 2 › Vibrio parahaemolyticus thermostable direct hemolysin | 0.50 | 41.0 | 3.20e-01 | 93.8% | 86.4% |
| 2ddmB00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.50 | 38.0 | 2.57e-01 | 84.4% | 86.7% |
ECOD (68)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3553582 | 5.1.4.283 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › ANAPC4_WD40, WD40_APC4_C-half | 0.65 | 48.0 | 2.88e-01 | 78.1% | 41.3% |
| 3701675 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.64 | 43.0 | 4.29e-01 | 70.3% | 83.8% |
| 3721595 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.64 | 45.0 | 3.59e-01 | 75.0% | 77.0% |
| 3513352 | 241.15.1.3 ↗ | a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › SPC25 | 0.63 | 52.0 | 4.38e-01 | 93.8% | 80.9% |
| 3243872 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.62 | 46.0 | 3.04e-01 | 81.2% | 48.6% |
| 3640668 | 719.1.1.2 ↗ | beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › XLF | 0.61 | 45.0 | 3.72e-01 | 81.2% | 86.4% |
| 3324335 | 881.1.1.1 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › PsbP | 0.60 | 46.0 | 3.40e-01 | 82.8% | 76.5% |
| 3628210 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.60 | 47.0 | 4.27e-01 | 84.4% | 92.9% |
| 5027014 | 246.2.1.9 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos_2 | 0.60 | 45.0 | 3.30e-01 | 82.8% | 59.0% |
| 3998221 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.60 | 47.0 | 3.64e-01 | 85.9% | 46.9% |
| 3987711 | 5.1.2.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed | 0.59 | 45.0 | 2.91e-01 | 84.4% | 27.3% |
| 5050683 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.59 | 36.0 | 2.92e-01 | 71.9% | 30.4% |
| 3387958 | 868.1.1.0 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related | 0.59 | 48.0 | 3.72e-01 | 100.0% | 38.7% |
| 4528719 | 4.1.1.438 ↗ | beta barrels › SH3 › SH3 › SH3 › PF27440 | 0.59 | 51.0 | 5.14e-01 | 100.0% | 98.5% |
| 3616263 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.59 | 48.0 | 4.13e-01 | 89.1% | 69.0% |
| 4292696 | 4263.2.1.0 ↗ | a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain | 0.59 | 45.0 | 4.34e-01 | 85.9% | 85.3% |
| 5052185 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.58 | 43.0 | 3.48e-01 | 81.2% | 66.9% |
| 3322492 | 5.1.4.550 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Kelch_FKB95 | 0.58 | 44.0 | 2.88e-01 | 84.4% | 26.7% |
| 4932472 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.58 | 46.0 | 4.07e-01 | 87.5% | 68.4% |
| 4990980 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.58 | 42.0 | 3.76e-01 | 79.7% | 65.3% |
| 3402087 | 868.1.1.0 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related | 0.58 | 48.0 | 3.69e-01 | 100.0% | 39.4% |
| 4012633 | 277.1.1.0 ↗ | a+b two layers › PX domain › PX domain › PX domain | 0.57 | 44.0 | 3.39e-01 | 87.5% | 71.5% |
| 3588533 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.57 | 50.0 | 3.61e-01 | 100.0% | 45.8% |
| 4120507 | 292.2.1.1 ↗ | a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › POLO_box | 0.57 | 47.0 | 4.12e-01 | 100.0% | 61.1% |
| 3215204 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.57 | 39.0 | 2.73e-01 | 93.8% | 19.3% |
| 3306468 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.57 | 48.0 | 3.60e-01 | 100.0% | 38.3% |
| 3714612 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.57 | 41.0 | 3.11e-01 | 78.1% | 70.3% |
| 3570615 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.57 | 45.0 | 3.96e-01 | 89.1% | 88.0% |
| 3960733 | 330.8.1.1 ↗ | a+b two layers › dsRBD-like › Rv2632c-like › Rv2632c-like › Rv2632c-like | 0.57 | 40.0 | 3.65e-01 | 75.0% | 55.3% |
| 3697999 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 47.0 | 3.18e-01 | 93.8% | 39.2% |
| 3519117 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.56 | 48.0 | 3.45e-01 | 95.3% | 60.0% |
| 3731305 | 219.1.1.93 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF6540 | 0.56 | 44.0 | 3.66e-01 | 100.0% | 46.4% |
| 2447618 | 5.1.4.12 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Sema | 0.56 | 44.0 | 3.03e-01 | 92.2% | 41.2% |
| 3586391 | 3937.1.1.2 ↗ | alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin | 0.56 | 40.0 | 2.62e-01 | 76.6% | 65.5% |
| 3476559 | 5.1.13.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › Propeller domain of DCAF15 › DCAF15_WD40 | 0.56 | 46.0 | 2.97e-01 | 95.3% | 34.5% |
| 3702442 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.56 | 42.0 | 3.65e-01 | 81.2% | 73.0% |
| 3603056 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.56 | 46.0 | 4.42e-01 | 93.8% | 88.0% |
| 3420092 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.56 | 37.0 | 3.52e-01 | 70.3% | 66.3% |
| 3623942 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.56 | 36.0 | 3.73e-01 | 71.9% | 72.4% |
| 3951937 | 330.8.1.1 ↗ | a+b two layers › dsRBD-like › Rv2632c-like › Rv2632c-like › Rv2632c-like | 0.55 | 39.0 | 3.51e-01 | 75.0% | 51.7% |
| 3515632 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.55 | 46.0 | 3.83e-01 | 95.3% | 82.5% |
| 3211832 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.55 | 43.0 | 2.87e-01 | 89.1% | 43.3% |
| 3509569 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.55 | 45.0 | 3.73e-01 | 87.5% | 82.7% |
| 4960002 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.55 | 44.0 | 4.02e-01 | 92.2% | 82.2% |
| 4959998 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 44.0 | 3.78e-01 | 90.6% | 77.1% |
| 4359254 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.54 | 41.0 | 3.95e-01 | 84.4% | 80.0% |
| 3322461 | 4.1.1.94 ↗ | beta barrels › SH3 › SH3 › SH3 › SAWADEE | 0.54 | 43.0 | 4.41e-01 | 95.3% | 96.7% |
| 3200064 | 219.1.1.93 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF6540 | 0.53 | 42.0 | 3.49e-01 | 100.0% | 46.4% |
| 5049326 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.53 | 39.0 | 3.21e-01 | 79.7% | 78.4% |
| 4953666 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.53 | 40.0 | 3.20e-01 | 84.4% | 38.6% |
| 3718300 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.53 | 39.0 | 3.77e-01 | 81.2% | 72.0% |
| 5011595 | 330.10.1.1 ↗ | a+b two layers › dsRBD-like › Heterocyclase TruD C-terminal domain › Heterocyclase TruD C-terminal domain › YcaO | 0.53 | 45.0 | 3.69e-01 | 100.0% | 95.4% |
| 4974776 | 881.1.1.1 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › PsbP | 0.53 | 43.0 | 3.38e-01 | 92.2% | 40.0% |
| 3987123 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.53 | 43.0 | 3.89e-01 | 92.2% | 64.4% |
| 4991285 | 11.1.4.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like | 0.53 | 43.0 | 4.05e-01 | 92.2% | 95.0% |
| 4974736 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.53 | 44.0 | 3.42e-01 | 93.8% | 42.1% |
| 2464202 | 295.1.1.1 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PC4 | 0.53 | 44.0 | 4.03e-01 | 92.2% | 69.9% |
| 3288884 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.52 | 37.0 | 3.29e-01 | 85.9% | 47.6% |
| 3588663 | 9.4.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › D-aminopeptidase, middle and C-terminal domains › D-aminopeptidase, middle and C-terminal domains | 0.52 | 42.0 | 3.80e-01 | 95.3% | 96.8% |
| 5030187 | 284.1.3.0 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain | 0.52 | 37.0 | 3.48e-01 | 75.0% | 85.9% |
| 4827588 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.52 | 41.0 | 3.16e-01 | 92.2% | 75.4% |
| 3173378 | 109.4.1.338 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RIC1 | 0.52 | 35.0 | 2.49e-01 | 84.4% | 19.2% |
| 3626079 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.51 | 41.0 | 2.69e-01 | 92.2% | 40.9% |
| 4961746 | 304.8.1.122 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DmsR_N | 0.51 | 41.0 | 3.50e-01 | 93.8% | 58.3% |
| 3512689 | 5.1.4.155 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MIOS_WD40 | 0.51 | 40.0 | 2.65e-01 | 93.8% | 25.4% |
| 4403166 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.51 | 39.0 | 3.95e-01 | 85.9% | 93.8% |
| 4941649 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.51 | 39.0 | 3.58e-01 | 90.6% | 72.6% |
| 1684916 | 9.1.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin | 0.51 | 41.0 | 3.27e-01 | 98.4% | 69.3% |
D2
high
residues 75-137
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF24132.2 best | DUF7399 | 55.4 | 1.20e-14 | 100.0% | 44.0% |
CATH (71)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2cazD00 | 6.10.140.820 | Special › Helix non-globular › Helix Hairpins › | 0.92 | 78.0 | 8.04e-01 | 92.1% | 95.0% |
| 3n2oA03 | 1.20.58.930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.91 | 77.0 | 6.52e-01 | 88.9% | 58.3% |
| 1t7sA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.91 | 79.0 | 6.09e-01 | 100.0% | 45.7% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.90 | 83.0 | 6.81e-01 | 100.0% | 61.7% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.89 | 82.0 | 7.04e-01 | 100.0% | 68.8% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.88 | 81.0 | 7.04e-01 | 100.0% | 71.7% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.87 | 79.0 | 5.87e-01 | 100.0% | 42.8% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.86 | 79.0 | 6.54e-01 | 100.0% | 60.4% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.86 | 64.0 | 7.04e-01 | 88.9% | 100.0% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.86 | 78.0 | 7.17e-01 | 98.4% | 96.2% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.86 | 78.0 | 7.42e-01 | 100.0% | 89.0% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.85 | 76.0 | 5.16e-01 | 98.4% | 51.0% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.84 | 66.0 | 6.22e-01 | 88.9% | 70.1% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.84 | 69.0 | 5.57e-01 | 93.7% | 48.3% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.83 | 75.0 | 5.28e-01 | 100.0% | 98.9% |
| 3tklB01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 72.0 | 7.34e-01 | 93.7% | 98.4% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.83 | 74.0 | 6.83e-01 | 100.0% | 82.7% |
| 3rx6A00 | 1.20.58.1090 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer | 0.82 | 74.0 | 5.21e-01 | 100.0% | 38.0% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.82 | 66.0 | 6.82e-01 | 87.3% | 100.0% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 73.0 | 6.23e-01 | 100.0% | 68.6% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.82 | 74.0 | 7.06e-01 | 100.0% | 94.4% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.81 | 67.0 | 6.05e-01 | 92.1% | 67.1% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.81 | 72.0 | 4.79e-01 | 100.0% | 30.6% |
| 2i2xB01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.81 | 65.0 | 5.49e-01 | 85.7% | 56.0% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.81 | 71.0 | 6.62e-01 | 100.0% | 79.2% |
| 7wivA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.80 | 70.0 | 4.45e-01 | 100.0% | 20.2% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.80 | 71.0 | 6.07e-01 | 100.0% | 80.2% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 71.0 | 5.27e-01 | 100.0% | 90.6% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.80 | 68.0 | 6.96e-01 | 98.4% | 100.0% |
| 4biuE01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.80 | 69.0 | 6.00e-01 | 100.0% | 63.3% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.80 | 68.0 | 6.97e-01 | 95.2% | 100.0% |
| 7sgrA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.80 | 71.0 | 4.48e-01 | 100.0% | 20.3% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 70.0 | 6.62e-01 | 100.0% | 92.0% |
| 2pmsC00 | 6.10.140.920 | Special › Helix non-globular › Helix Hairpins › | 0.79 | 70.0 | 5.80e-01 | 98.4% | 66.1% |
| 1cxzB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.79 | 67.0 | 6.05e-01 | 100.0% | 69.8% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.79 | 63.0 | 5.68e-01 | 93.7% | 63.2% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.79 | 69.0 | 6.29e-01 | 100.0% | 74.7% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 70.0 | 5.57e-01 | 98.4% | 60.7% |
| 3zdmB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.79 | 54.0 | 5.90e-01 | 79.4% | 90.0% |
| 3dytA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 68.0 | 4.89e-01 | 100.0% | 33.2% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.78 | 68.0 | 6.21e-01 | 100.0% | 74.4% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 68.0 | 6.32e-01 | 100.0% | 79.0% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.78 | 69.0 | 4.65e-01 | 100.0% | 58.5% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.78 | 65.0 | 6.28e-01 | 98.4% | 83.1% |
| 3sfvB02 | 6.10.140.2010 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 66.0 | 4.60e-01 | 95.2% | 48.0% |
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.78 | 68.0 | 4.29e-01 | 100.0% | 42.5% |
| 4aurA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.77 | 68.0 | 4.36e-01 | 95.2% | 37.6% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 63.0 | 6.01e-01 | 92.1% | 81.6% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.77 | 67.0 | 5.84e-01 | 100.0% | 63.3% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.77 | 61.0 | 5.84e-01 | 87.3% | 75.7% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 67.0 | 6.05e-01 | 100.0% | 71.6% |
| 5azsC01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.77 | 67.0 | 4.17e-01 | 100.0% | 89.4% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.77 | 67.0 | 5.63e-01 | 100.0% | 58.2% |
| 3jcuZ00 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.76 | 62.0 | 6.31e-01 | 92.1% | 93.4% |
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.76 | 62.0 | 6.45e-01 | 92.1% | 100.0% |
| 4cpgA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.75 | 51.0 | 5.00e-01 | 79.4% | 65.2% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.74 | 63.0 | 5.09e-01 | 92.1% | 51.3% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.74 | 64.0 | 6.17e-01 | 100.0% | 86.3% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 62.0 | 6.18e-01 | 98.4% | 94.0% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.73 | 62.0 | 3.96e-01 | 100.0% | 19.3% |
| 2pvqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.73 | 60.0 | 5.13e-01 | 100.0% | 55.7% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 62.0 | 5.41e-01 | 98.4% | 91.9% |
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.72 | 48.0 | 4.52e-01 | 96.8% | 55.7% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 57.0 | 4.53e-01 | 95.2% | 42.4% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.71 | 64.0 | 5.25e-01 | 98.4% | 72.5% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.70 | 60.0 | 5.47e-01 | 98.4% | 78.8% |
| 1bhaA00 | 1.10.287.170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 59.0 | 5.78e-01 | 92.1% | 91.0% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.69 | 59.0 | 5.53e-01 | 96.8% | 80.8% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.69 | 60.0 | 5.04e-01 | 98.4% | 68.8% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 54.0 | 5.48e-01 | 98.4% | 96.9% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 56.0 | 5.58e-01 | 98.4% | 93.8% |
ECOD (78)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5043437 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.97 | 93.0 | 7.55e-01 | 100.0% | 60.0% |
| 4971062 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.96 | 91.0 | 8.03e-01 | 100.0% | 74.1% |
| 3268365 | 192.15.1.3 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Vps23_core | 0.95 | 88.0 | 6.15e-01 | 96.8% | 35.9% |
| 3486312 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.95 | 90.0 | 7.02e-01 | 100.0% | 52.9% |
| 2636640 | 192.15.1.3 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Vps23_core | 0.95 | 87.0 | 8.02e-01 | 96.8% | 79.2% |
| 5032512 | 5086.1.1.234 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › CdvA | 0.95 | 89.0 | 6.69e-01 | 100.0% | 46.7% |
| 3928861 | 192.15.1.3 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Vps23_core | 0.95 | 87.0 | 6.18e-01 | 96.8% | 38.1% |
| 4934678 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.94 | 89.0 | 6.16e-01 | 100.0% | 35.0% |
| 3997665 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.94 | 88.0 | 7.05e-01 | 100.0% | 55.8% |
| 3187917 | 192.15.1.3 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Vps23_core | 0.93 | 85.0 | 6.01e-01 | 96.8% | 37.0% |
| 5067407 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.93 | 86.0 | 6.98e-01 | 100.0% | 57.3% |
| 5027389 | 603.1.1.241 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › CdvA | 0.93 | 86.0 | 6.89e-01 | 100.0% | 54.8% |
| 3279544 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.90 | 85.0 | 5.28e-01 | 100.0% | 45.8% |
| 3962991 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.88 | 81.0 | 5.59e-01 | 100.0% | 33.8% |
| 4036645 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.87 | 80.0 | 5.50e-01 | 100.0% | 51.8% |
| 3829344 | 3922.1.1.295 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF7653 | 0.85 | 78.0 | 5.28e-01 | 100.0% | 38.6% |
| 3491738 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.85 | 77.0 | 6.57e-01 | 100.0% | 66.7% |
| 4228031 | 109.4.1.128 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G_like_2 | 0.85 | 76.0 | 4.85e-01 | 100.0% | 22.9% |
| 3396370 | 192.15.1.2 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r | 0.85 | 77.0 | 5.62e-01 | 100.0% | 39.4% |
| 3619654 | 192.15.1.2 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r | 0.85 | 77.0 | 5.47e-01 | 100.0% | 36.0% |
| 4663904 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.84 | 76.0 | 6.45e-01 | 100.0% | 64.0% |
| 3791357 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.84 | 75.0 | 5.48e-01 | 100.0% | 38.2% |
| 4994917 | 3834.1.1.25 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 | 0.84 | 76.0 | 4.99e-01 | 100.0% | 92.2% |
| 3973283 | 325.1.7.27 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_AprE | 0.84 | 76.0 | 5.28e-01 | 100.0% | 37.4% |
| None | — | 0.83 | 74.0 | 5.81e-01 | 100.0% | 48.5% | |
| 3969543 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 74.0 | 7.02e-01 | 100.0% | 85.3% |
| 4046042 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 74.0 | 5.87e-01 | 100.0% | 51.2% |
| 3944501 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.82 | 74.0 | 6.80e-01 | 100.0% | 78.8% |
| 3967813 | 5086.1.1.93 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA | 0.82 | 73.0 | 5.75e-01 | 100.0% | 49.2% |
| 3975632 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.82 | 70.0 | 4.93e-01 | 100.0% | 31.9% |
| 3984493 | 325.1.7.28 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_YBHG | 0.82 | 72.0 | 5.72e-01 | 100.0% | 49.2% |
| 3560925 | 604.1.1.20 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › AKNA | 0.82 | 72.0 | 5.99e-01 | 100.0% | 57.3% |
| 3973899 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.82 | 69.0 | 5.25e-01 | 100.0% | 40.7% |
| 3971026 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 72.0 | 5.76e-01 | 100.0% | 51.2% |
| 3945031 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.81 | 72.0 | 5.69e-01 | 100.0% | 49.2% |
| 3473827 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 69.0 | 7.10e-01 | 96.8% | 100.0% |
| 3974573 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.81 | 72.0 | 5.67e-01 | 100.0% | 49.2% |
| 4629385 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 72.0 | 5.43e-01 | 100.0% | 77.3% |
| 4362754 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.81 | 70.0 | 5.69e-01 | 98.4% | 51.7% |
| 3973695 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 71.0 | 5.03e-01 | 100.0% | 50.0% |
| 3386973 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.80 | 71.0 | 6.31e-01 | 100.0% | 71.1% |
| 3968781 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 71.0 | 5.41e-01 | 100.0% | 44.1% |
| 3974625 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.80 | 70.0 | 6.84e-01 | 100.0% | 91.4% |
| 3987006 | 5086.1.1.93 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA | 0.80 | 70.0 | 5.45e-01 | 100.0% | 45.7% |
| 4009031 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 71.0 | 6.41e-01 | 100.0% | 75.3% |
| 4525341 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 70.0 | 6.79e-01 | 100.0% | 91.4% |
| 3969814 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.80 | 70.0 | 6.65e-01 | 100.0% | 85.3% |
| 3166260 | 1.1.7.123 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25885 | 0.79 | 70.0 | 5.53e-01 | 100.0% | 49.2% |
| 3973285 | 3755.1.1.28 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › PF25876 | 0.79 | 70.0 | 5.46e-01 | 100.0% | 47.4% |
| 4642325 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.79 | 70.0 | 5.55e-01 | 100.0% | 49.2% |
| 5083949 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.79 | 69.0 | 5.51e-01 | 100.0% | 49.2% |
| 4267909 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.79 | 70.0 | 4.93e-01 | 100.0% | 37.4% |
| 3965957 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.79 | 69.0 | 6.56e-01 | 100.0% | 85.3% |
| 3947741 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.79 | 69.0 | 5.63e-01 | 100.0% | 53.3% |
| 3964486 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.79 | 68.0 | 5.09e-01 | 98.4% | 39.4% |
| 3948872 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.78 | 68.0 | 5.41e-01 | 100.0% | 49.2% |
| 4174593 | 3922.1.1.248 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF25876 | 0.78 | 68.0 | 6.48e-01 | 100.0% | 85.3% |
| 3838083 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.78 | 67.0 | 6.55e-01 | 98.4% | 98.6% |
| 3974231 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.78 | 69.0 | 6.71e-01 | 100.0% | 90.0% |
| 3981585 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.78 | 68.0 | 6.47e-01 | 100.0% | 85.3% |
| 4010479 | 325.1.7.48 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25885 | 0.78 | 68.0 | 5.41e-01 | 100.0% | 49.2% |
| 4523639 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.78 | 68.0 | 4.84e-01 | 100.0% | 35.3% |
| 3941960 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.77 | 67.0 | 5.44e-01 | 100.0% | 50.4% |
| 4006721 | 325.1.7.50 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25876 | 0.77 | 67.0 | 6.16e-01 | 100.0% | 75.3% |
| 3964187 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.77 | 68.0 | 6.30e-01 | 100.0% | 91.3% |
| 3620978 | 2003.1.2.18 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.77 | 67.0 | 4.27e-01 | 100.0% | 31.9% |
| 3971758 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.77 | 66.0 | 6.06e-01 | 98.4% | 74.1% |
| 3165089 | 5086.1.1.190 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › OEP | 0.77 | 67.0 | 4.64e-01 | 100.0% | 29.1% |
| 3973636 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.76 | 66.0 | 6.30e-01 | 100.0% | 85.3% |
| 1759951 | 5086.1.1.88 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD | 0.75 | 65.0 | 4.69e-01 | 100.0% | 33.3% |
| 4175809 | 5086.1.1.88 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD | 0.75 | 65.0 | 4.85e-01 | 100.0% | 38.8% |
| 1313624 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.74 | 63.0 | 4.74e-01 | 98.4% | 37.7% |
| 3278215 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.74 | 65.0 | 5.91e-01 | 100.0% | 74.1% |
| 3978264 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.74 | 64.0 | 4.87e-01 | 98.4% | 56.0% |
| 3984078 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.73 | 63.0 | 4.12e-01 | 100.0% | 21.7% |
| 3982740 | 5086.1.1.190 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › OEP | 0.73 | 63.0 | 4.46e-01 | 100.0% | 31.0% |
| 4659928 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.71 | 59.0 | 5.07e-01 | 98.4% | 56.4% |
| 5070736 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.70 | 59.0 | 4.27e-01 | 100.0% | 32.0% |