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IMGVR_UViG_3300014887_000003-3300014887-Ga0180302_100000272
Arc-VirIMGVR_UViG_3300014887_000003-3300014887-Ga0180302_100000272
Identity
- Kingdom:
- archaea
Quality
85.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-68
Domain cluster:
representative
CATH (56)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 71.0 | 6.19e-01 | 100.0% | 60.8% |
| 3fblA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 68.0 | 6.39e-01 | 100.0% | 74.4% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.79 | 50.0 | 4.61e-01 | 72.1% | 51.8% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.79 | 58.0 | 4.87e-01 | 80.9% | 47.3% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.71 | 52.0 | 3.54e-01 | 77.9% | 22.4% |
| 3nkzA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.71 | 53.0 | 4.70e-01 | 80.9% | 55.7% |
| 4mi2A02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.70 | 47.0 | 5.02e-01 | 76.5% | 81.0% |
| 4zqeA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.70 | 48.0 | 4.26e-01 | 72.1% | 50.0% |
| 4dveA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.69 | 57.0 | 4.19e-01 | 92.6% | 68.3% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.69 | 59.0 | 5.32e-01 | 100.0% | 75.3% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.68 | 60.0 | 4.86e-01 | 100.0% | 83.5% |
| 1kl9A02 | 1.10.150.190 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 | 0.68 | 46.0 | 4.17e-01 | 70.6% | 60.9% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.68 | 47.0 | 3.63e-01 | 75.0% | 31.2% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.68 | 58.0 | 4.93e-01 | 100.0% | 87.2% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.67 | 50.0 | 4.48e-01 | 91.2% | 57.4% |
| 3hugA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.67 | 51.0 | 4.85e-01 | 82.4% | 88.7% |
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.66 | 48.0 | 4.05e-01 | 76.5% | 77.0% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.65 | 42.0 | 4.73e-01 | 89.7% | 88.2% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 49.0 | 3.53e-01 | 80.9% | 32.0% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.64 | 54.0 | 4.59e-01 | 98.5% | 59.5% |
| 2lmgA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 45.0 | 4.41e-01 | 86.8% | 68.9% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.63 | 54.0 | 5.21e-01 | 100.0% | 87.3% |
| 1zk8B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 53.0 | 4.35e-01 | 100.0% | 50.0% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.63 | 54.0 | 4.21e-01 | 97.1% | 47.0% |
| 2qe7G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.62 | 44.0 | 3.95e-01 | 92.6% | 52.6% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.62 | 53.0 | 4.29e-01 | 97.1% | 72.2% |
| 3p42A02 | 6.10.250.2280 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.62 | 46.0 | 4.63e-01 | 80.9% | 97.1% |
| 1rqgA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.61 | 52.0 | 4.13e-01 | 98.5% | 53.0% |
| 1l3pA00 | 1.20.120.320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen | 0.61 | 52.0 | 4.61e-01 | 98.5% | 84.3% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.60 | 51.0 | 4.10e-01 | 100.0% | 48.5% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.59 | 47.0 | 4.37e-01 | 86.8% | 73.6% |
| 2xppA00 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.59 | 50.0 | 3.97e-01 | 100.0% | 46.0% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 52.0 | 4.64e-01 | 100.0% | 78.4% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.58 | 44.0 | 4.34e-01 | 85.3% | 77.5% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 49.0 | 4.10e-01 | 94.1% | 68.6% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 50.0 | 3.79e-01 | 98.5% | 76.2% |
| 4gouA01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.58 | 47.0 | 3.74e-01 | 91.2% | 52.0% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 52.0 | 4.52e-01 | 100.0% | 99.0% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.58 | 49.0 | 3.99e-01 | 94.1% | 68.8% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.58 | 51.0 | 4.34e-01 | 100.0% | 84.1% |
| 4akrA01 | 3.30.1140.60 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › F-actin capping protein, alpha subunit | 0.58 | 44.0 | 3.86e-01 | 83.8% | 72.6% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.57 | 47.0 | 4.38e-01 | 95.6% | 76.4% |
| 2psmA00 | 1.20.1250.70 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 | 0.57 | 47.0 | 3.98e-01 | 91.2% | 94.9% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.57 | 49.0 | 4.53e-01 | 94.1% | 83.9% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 47.0 | 4.64e-01 | 100.0% | 84.0% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 50.0 | 4.51e-01 | 100.0% | 80.6% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 49.0 | 4.57e-01 | 100.0% | 89.5% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 48.0 | 4.21e-01 | 100.0% | 94.4% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 44.0 | 4.30e-01 | 91.2% | 78.4% |
| 4nqwA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 40.0 | 4.18e-01 | 77.9% | 95.3% |
| 3b0pA02 | 1.20.120.1460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 48.0 | 4.63e-01 | 94.1% | 85.3% |
| 1yhuB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 45.0 | 3.62e-01 | 94.1% | 88.2% |
| 7ae2A01 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.54 | 47.0 | 3.76e-01 | 97.1% | 94.2% |
| 5fgmA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 39.0 | 4.01e-01 | 77.9% | 92.3% |
| 3ktdD02 | 1.10.3660.10 | Mainly Alpha › Orthogonal Bundle › 6-phosphogluconate dehydrogenase C-terminal fold › 6-phosphogluconate dehydrogenase C-terminal like domain | 0.53 | 47.0 | 4.04e-01 | 100.0% | 67.9% |
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.53 | 47.0 | 4.02e-01 | 100.0% | 64.5% |
ECOD (53)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4528425 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.80 | 72.0 | 6.27e-01 | 98.5% | 68.0% |
| 4346135 | 3921.1.1.0 ↗ | alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D | 0.80 | 72.0 | 5.25e-01 | 100.0% | 42.8% |
| 4927047 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.78 | 56.0 | 5.45e-01 | 76.5% | 69.3% |
| 3653641 | 10.12.1.3 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_1 | 0.77 | 51.0 | 3.38e-01 | 72.1% | 17.4% |
| 4269627 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.75 | 59.0 | 5.39e-01 | 91.2% | 64.4% |
| 4963961 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.75 | 65.0 | 4.75e-01 | 100.0% | 81.1% |
| 3742906 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.74 | 59.0 | 4.79e-01 | 85.3% | 52.8% |
| 4442725 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.74 | 63.0 | 3.77e-01 | 94.1% | 14.6% |
| 4022294 | 1025.1.1.0 ↗ | alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain | 0.74 | 51.0 | 4.36e-01 | 91.2% | 46.7% |
| 4018548 | 1025.1.1.0 ↗ | alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain | 0.74 | 53.0 | 4.45e-01 | 86.8% | 46.4% |
| 4391867 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.73 | 62.0 | 3.73e-01 | 94.1% | 15.1% |
| 4021431 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 56.0 | 4.37e-01 | 82.4% | 88.6% |
| 4886107 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.72 | 63.0 | 5.60e-01 | 100.0% | 76.0% |
| 4034213 | 632.2.1.5 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1542 | 0.72 | 53.0 | 5.07e-01 | 80.9% | 67.5% |
| 3731708 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 51.0 | 4.47e-01 | 86.8% | 49.5% |
| 3633170 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.71 | 57.0 | 4.74e-01 | 88.2% | 55.0% |
| 3477179 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.69 | 50.0 | 4.65e-01 | 77.9% | 61.2% |
| 3259409 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.68 | 54.0 | 4.25e-01 | 85.3% | 65.7% |
| 3477766 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.68 | 58.0 | 5.42e-01 | 100.0% | 76.5% |
| 4823728 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.68 | 48.0 | 4.16e-01 | 86.8% | 49.0% |
| 3257705 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.67 | 51.0 | 4.57e-01 | 86.8% | 57.9% |
| 3732730 | 243.9.1.2 ↗ | a+b two layers › Cystatin-like › Nuclease A inhibitor (NuiA)-related › Nuclease A inhibitor (NuiA)-related › Maf1 | 0.67 | 46.0 | 3.25e-01 | 97.1% | 22.3% |
| 4479551 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.66 | 52.0 | 4.80e-01 | 92.6% | 65.6% |
| 4030778 | 632.2.1.5 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1542 | 0.66 | 47.0 | 4.55e-01 | 77.9% | 66.3% |
| 3421877 | 206.1.1.14 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 | 0.65 | 57.0 | 3.48e-01 | 100.0% | 38.7% |
| 4260212 | 4967.1.1.6 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2 | 0.64 | 56.0 | 4.58e-01 | 100.0% | 81.5% |
| 3211724 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.63 | 47.0 | 4.19e-01 | 85.3% | 56.8% |
| 4552467 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.63 | 54.0 | 3.49e-01 | 100.0% | 32.1% |
| 3621994 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 50.0 | 4.04e-01 | 100.0% | 45.9% |
| 3463676 | 109.4.1.1186 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF6857 | 0.61 | 54.0 | 4.12e-01 | 100.0% | 43.2% |
| 3518321 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 54.0 | 4.53e-01 | 100.0% | 78.3% |
| 3660443 | 604.6.1.40 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › PF27980 | 0.60 | 53.0 | 4.88e-01 | 100.0% | 83.3% |
| 3477269 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.60 | 48.0 | 3.63e-01 | 85.3% | 37.4% |
| 3497466 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.59 | 53.0 | 4.83e-01 | 100.0% | 80.0% |
| 3645555 | 3817.1.1.1 ↗ | alpha bundles › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Pex19 | 0.58 | 44.0 | 3.68e-01 | 83.8% | 95.1% |
| 3242683 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.58 | 49.0 | 4.47e-01 | 92.6% | 77.8% |
| 3668286 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.58 | 45.0 | 4.52e-01 | 95.6% | 84.3% |
| 3815026 | 604.1.1.148 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N | 0.58 | 50.0 | 4.70e-01 | 100.0% | 87.1% |
| 3754249 | 109.26.1.12 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_Nup160_C, TPR_NUP160_120_M | 0.57 | 41.0 | 2.98e-01 | 89.7% | 24.0% |
| 3508186 | 7558.1.1.1 ↗ | a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Acyltransferase | 0.57 | 50.0 | 3.30e-01 | 100.0% | 39.0% |
| 4480963 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.57 | 44.0 | 3.85e-01 | 83.8% | 65.7% |
| 4952624 | 3843.1.1.29 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2105 | 0.57 | 48.0 | 4.45e-01 | 100.0% | 74.1% |
| 3241724 | 109.4.1.587 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mon2_C | 0.57 | 47.0 | 3.02e-01 | 100.0% | 18.8% |
| 3182665 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.56 | 47.0 | 4.25e-01 | 92.6% | 76.8% |
| 3877229 | 109.4.1.1394 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_12 | 0.56 | 50.0 | 3.46e-01 | 100.0% | 28.9% |
| 3261105 | 632.11.1.2 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DOCK_N | 0.56 | 44.0 | 3.98e-01 | 86.8% | 80.0% |
| 3598180 | 611.4.1.0 ↗ | alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like | 0.56 | 45.0 | 3.82e-01 | 88.2% | 60.0% |
| 5059032 | 4070.1.1.0 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like | 0.56 | 46.0 | 3.50e-01 | 100.0% | 44.6% |
| 3595261 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.55 | 49.0 | 4.44e-01 | 98.5% | 73.3% |
| 2157267 | 109.4.1.204 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_EZ | 0.55 | 48.0 | 4.05e-01 | 100.0% | 62.1% |
| 5079439 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.55 | 48.0 | 4.16e-01 | 98.5% | 89.5% |
| 3864432 | 632.11.1.2 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DOCK_N | 0.54 | 42.0 | 3.85e-01 | 82.4% | 70.0% |
| None | — | 0.50 | 42.0 | 3.57e-01 | 91.2% | 80.9% |
D2
medium
residues 69-147
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8b9zK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.85 | 59.0 | 5.57e-01 | 70.9% | 62.6% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 55.0 | 6.01e-01 | 70.9% | 86.2% |
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.78 | 54.0 | 5.12e-01 | 70.9% | 62.6% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.76 | 52.0 | 5.37e-01 | 70.9% | 78.4% |
| 7zmgL01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 51.0 | 5.17e-01 | 70.9% | 72.5% |
| 5xtck00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 50.0 | 4.66e-01 | 70.9% | 58.8% |
| 2rgnB01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.65 | 45.0 | 3.38e-01 | 72.2% | 74.5% |
| 2x43S00 | 6.10.140.1430 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 42.0 | 4.49e-01 | 92.4% | 82.1% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.59 | 42.0 | 4.41e-01 | 74.7% | 83.1% |
| 7lv8A01 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.58 | 44.0 | 4.36e-01 | 81.0% | 79.8% |
| 2aplA02 | 1.10.8.340 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like | 0.57 | 38.0 | 3.84e-01 | 96.2% | 66.7% |
| 2w43A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.56 | 36.0 | 4.13e-01 | 93.7% | 91.2% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 40.0 | 4.34e-01 | 78.5% | 90.9% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 44.0 | 3.70e-01 | 96.2% | 52.2% |
| 1aueB00 | 1.20.120.150 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › FKBP12-rapamycin binding domain | 0.53 | 45.0 | 4.25e-01 | 93.7% | 100.0% |
| 1zhcA00 | 6.10.280.50 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 38.0 | 3.92e-01 | 98.7% | 84.2% |
| 7tzoA01 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.51 | 42.0 | 3.39e-01 | 94.9% | 59.8% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 44.0 | 3.68e-01 | 100.0% | 83.1% |
| 3b0cW00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.51 | 41.0 | 4.25e-01 | 94.9% | 100.0% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4034326 | 5043.1.1.0 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like | 0.81 | 55.0 | 6.39e-01 | 70.9% | 100.0% |
| 3719405 | 3447.1.1.1 ↗ | alpha bundles › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › Isoprenylcysteine carboxyl methyltransferase (ICMT) › ERG4_ERG24 | 0.80 | 55.0 | 3.83e-01 | 70.9% | 30.3% |
| 3947564 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.75 | 52.0 | 5.65e-01 | 70.9% | 92.3% |
| 4623058 | 5043.1.1.0 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like | 0.74 | 51.0 | 5.47e-01 | 70.9% | 93.8% |
| 3630756 | 5043.1.1.2 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › SPC12 | 0.73 | 49.0 | 5.17e-01 | 70.9% | 78.6% |
| 4312332 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.73 | 51.0 | 5.00e-01 | 72.2% | 74.1% |
| 3389526 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.72 | 56.0 | 5.23e-01 | 98.7% | 66.0% |
| 5043880 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.68 | 56.0 | 5.49e-01 | 100.0% | 84.7% |
| 3985321 | 3579.1.1.29 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › ThrE_2 | 0.67 | 49.0 | 4.06e-01 | 100.0% | 42.8% |
| 4628602 | 5000.4.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › Endotoxin_N | 0.66 | 58.0 | 4.04e-01 | 98.7% | 30.0% |
| 4103507 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.66 | 52.0 | 4.96e-01 | 100.0% | 73.7% |
| 2768756 | 5073.1.1.4 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C,Cation_ATPase_N | 0.65 | 45.0 | 3.89e-01 | 92.4% | 46.7% |
| 4944568 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.65 | 44.0 | 4.74e-01 | 70.9% | 86.2% |
| 3399433 | 3826.1.1.39 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › WHEP-TRS | 0.64 | 47.0 | 4.90e-01 | 94.9% | 90.0% |
| 3263072 | 109.4.1.427 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SDA1_HEAT | 0.63 | 47.0 | 2.77e-01 | 79.7% | 14.8% |
| 3741398 | 632.1.1.8 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › SOG2 | 0.62 | 52.0 | 4.46e-01 | 98.7% | 56.9% |
| 5077009 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.62 | 54.0 | 3.99e-01 | 100.0% | 69.3% |
| 4927262 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.60 | 51.0 | 3.99e-01 | 98.7% | 44.3% |
| 4286656 | 140.1.1.11 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 | 0.58 | 39.0 | 3.57e-01 | 97.5% | 50.0% |
| 4928042 | 4275.1.1.0 ↗ | alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like | 0.58 | 48.0 | 4.67e-01 | 98.7% | 81.1% |
| 3703064 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.57 | 43.0 | 3.60e-01 | 81.0% | 47.1% |
| 4017010 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.57 | 46.0 | 3.92e-01 | 98.7% | 51.4% |
| 2487395 | 148.1.1.1 ↗ | alpha arrays › Histone-like › Histone-related › Histone › Histone | 0.55 | 45.0 | 4.22e-01 | 92.4% | 79.8% |
| 3616295 | 148.1.1.0 ↗ | alpha arrays › Histone-like › Histone-related › Histone | 0.54 | 44.0 | 4.30e-01 | 91.1% | 84.7% |
| 3599095 | 601.24.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0.54 | 44.0 | 4.13e-01 | 92.4% | 100.0% |