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IMGVR_UViG_3300014887_000003-3300014887-Ga0180302_1000002739

Arc-Vir

IMGVR_UViG_3300014887_000003-3300014887-Ga0180302_1000002739

Quality

91.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-143
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01751.29 best Toprim 48.1 1.50e-12 86.6% 99.0%
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4cgyA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.91 87.0 7.90e-01 97.9% 92.0%
6k8nA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.88 86.0 8.20e-01 100.0% 96.2%
1i7dA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.88 84.0 8.11e-01 100.0% 100.0%
5gvcB01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.85 80.0 7.58e-01 97.9% 98.8%
1gkuB05 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.85 70.0 7.58e-01 99.3% 99.2%
2gaiA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.84 72.0 7.60e-01 99.3% 97.7%
5uj1A01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.78 75.0 7.52e-01 100.0% 97.9%
1t6t200 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.68 44.0 5.01e-01 88.0% 84.5%
3t1oA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 56.0 5.03e-01 97.2% 90.6%
1tq8A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.61 36.0 3.76e-01 95.8% 63.8%
5t3uB00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.58 46.0 4.72e-01 97.9% 88.7%
3ihlB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 51.0 4.34e-01 95.8% 96.1%
1z06A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 51.0 4.86e-01 95.8% 97.6%
3bedA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.57 44.0 4.57e-01 98.6% 87.7%
1iv0A00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.56 37.0 4.33e-01 92.3% 96.9%
1mdbA01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 38.0 3.74e-01 95.1% 62.7%
1a3cA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 42.0 3.99e-01 97.9% 66.9%
6ebqA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.55 46.0 4.66e-01 95.8% 94.2%
2yfkA01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.54 40.0 3.67e-01 96.5% 58.2%
4m88A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 44.0 4.43e-01 100.0% 86.0%
3igfA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 47.0 3.90e-01 97.2% 98.8%
4rgyA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 47.0 3.99e-01 96.5% 87.8%
1u04A03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 43.0 4.01e-01 97.9% 69.1%
4dadA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 42.0 4.35e-01 95.8% 92.2%
6oz7B00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 47.0 4.03e-01 98.6% 93.6%
1eucB03 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.53 43.0 4.35e-01 95.8% 84.9%
4lw8A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 47.0 4.13e-01 98.6% 87.2%
3ga7A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 47.0 3.64e-01 97.2% 76.3%
2q9uA02 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.53 47.0 4.66e-01 95.8% 97.2%
5aunB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 43.0 3.72e-01 88.0% 86.5%
1mv8A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 46.0 4.14e-01 98.6% 99.5%
7ue1B01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.52 34.0 3.43e-01 92.3% 63.9%
4nesA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.51 44.0 4.01e-01 95.8% 98.5%
3fnrA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 44.0 3.48e-01 95.1% 93.8%
3ea0A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 44.0 3.75e-01 97.2% 85.0%
1xc3A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.50 35.0 4.00e-01 84.5% 99.0%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1144578 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.91 86.0 7.86e-01 97.2% 92.0%
4948253 2006.1.3.30 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Topoisom_bac 0.90 87.0 5.90e-01 100.0% 36.6%
3594771 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.90 86.0 8.15e-01 97.9% 98.8%
3692627 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.90 85.0 7.61e-01 97.9% 97.8%
4976525 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.90 85.0 8.10e-01 97.9% 100.0%
4943297 2006.1.3.30 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Topoisom_bac 0.90 84.0 8.12e-01 97.2% 97.4%
4930519 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.89 85.0 8.18e-01 97.9% 99.4%
3587568 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.89 85.0 8.32e-01 98.6% 99.3%
5071480 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.89 84.0 7.88e-01 97.9% 94.5%
5051950 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.89 83.0 7.99e-01 96.5% 99.4%
4973807 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.89 82.0 8.19e-01 95.8% 100.0%
3944064 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.89 85.0 7.20e-01 100.0% 73.0%
2904778 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 83.0 8.02e-01 97.2% 94.9%
4283078 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 84.0 8.10e-01 98.6% 98.1%
3623038 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 84.0 7.71e-01 99.3% 97.7%
4683136 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 77.0 8.10e-01 98.6% 99.2%
3926546 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 84.0 7.78e-01 99.3% 98.2%
5000445 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 82.0 7.73e-01 97.2% 93.3%
3655189 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 68.0 7.53e-01 99.3% 97.4%
5001224 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.87 82.0 7.16e-01 97.2% 99.0%
4933035 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.87 70.0 7.63e-01 98.6% 98.3%
3590579 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.86 80.0 7.79e-01 97.2% 99.4%
None 0.86 81.0 7.88e-01 99.3% 99.4%
None 0.85 76.0 7.92e-01 96.5% 100.0%
5003456 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.85 77.0 7.89e-01 96.5% 97.0%
5005178 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.85 78.0 7.66e-01 95.8% 98.7%
4988770 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.84 79.0 7.27e-01 97.2% 100.0%
4418350 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.84 80.0 7.04e-01 99.3% 97.9%
4392313 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.84 78.0 7.58e-01 97.2% 98.1%
4990152 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.84 77.0 7.94e-01 97.9% 100.0%
3440696 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.83 80.0 7.82e-01 98.6% 96.7%
3330964 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.83 76.0 7.05e-01 100.0% 78.8%
5036017 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.82 79.0 6.52e-01 100.0% 75.7%
4638791 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.82 75.0 6.80e-01 96.5% 96.2%
3165571 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.81 78.0 7.32e-01 99.3% 98.8%
1572168 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.81 75.0 6.92e-01 97.9% 97.2%
3786876 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.80 76.0 7.58e-01 97.9% 99.3%
3496158 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.80 75.0 7.52e-01 97.9% 98.6%
5008810 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.80 71.0 7.29e-01 97.9% 96.3%
4442595 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.79 76.0 5.60e-01 100.0% 43.7%
3953940 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.79 74.0 7.25e-01 97.2% 92.0%
4599785 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.77 72.0 7.29e-01 97.2% 98.6%
3593805 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.75 71.0 5.02e-01 100.0% 45.7%
5076183 7522.1.1.4 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II 0.70 52.0 5.48e-01 98.6% 84.6%
4270708 2006.1.3.7 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_4 0.59 46.0 4.72e-01 98.6% 85.2%
5022939 2484.1.1.23 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydantoinase_A 0.58 39.0 4.17e-01 100.0% 80.0%
3699857 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 50.0 4.00e-01 98.6% 100.0%
3502108 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.55 48.0 4.48e-01 95.8% 89.4%
4204988 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.55 39.0 4.37e-01 92.3% 96.4%
4155839 2007.3.1.1 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA 0.54 45.0 4.42e-01 95.8% 83.3%
4944063 2007.3.1.1 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA 0.54 43.0 4.39e-01 95.8% 86.4%
3956789 2484.1.1.144 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDD_Tnp_IS110 0.54 42.0 4.21e-01 100.0% 79.3%
3285731 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.54 45.0 4.49e-01 90.8% 95.2%
4952918 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.53 33.0 3.91e-01 87.3% 96.7%
4482972 2011.2.1.6 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › tRNA_deacylase 0.53 47.0 4.44e-01 95.8% 98.2%
3613176 2007.1.4.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain › DAGK_cat 0.53 46.0 4.03e-01 97.2% 85.9%
3278773 7579.1.1.23 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › PAF-AH_p_II 0.52 46.0 3.50e-01 97.2% 65.5%
None 0.52 46.0 3.08e-01 96.5% 67.1%
4486835 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.52 39.0 4.19e-01 92.3% 93.3%
4933350 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.51 39.0 4.13e-01 95.8% 92.2%
3467094 2003.1.1.43 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_3 0.51 44.0 3.99e-01 96.5% 96.0%
3329316 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.50 44.0 4.07e-01 96.5% 95.7%
D2 high residues 206-250_381-447
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4dduA07 2.60.510.20 Mainly Beta › Sandwich › EV matrix protein fold › 0.65 49.0 5.08e-01 81.2% 90.7%
1cyyA02 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.61 46.0 4.45e-01 79.5% 91.2%
1gkuB07 2.60.510.20 Mainly Beta › Sandwich › EV matrix protein fold › 0.59 46.0 4.79e-01 84.8% 98.0%
2gaiA03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.56 46.0 4.54e-01 92.0% 100.0%
2g16B00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.55 42.0 3.67e-01 78.6% 94.5%
1uebA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.55 31.0 4.01e-01 74.1% 100.0%
3cpfA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.53 31.0 3.88e-01 80.4% 100.0%
3oyyA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.53 31.0 3.79e-01 75.0% 97.0%
6j8yC00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.53 38.0 2.95e-01 76.8% 32.9%
3h0gH00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 37.0 3.66e-01 75.0% 100.0%
1iz6A01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.52 31.0 3.81e-01 78.6% 97.1%
3s98A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 25.0 2.87e-01 88.4% 61.0%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4258905 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.73 55.0 5.34e-01 79.5% 89.6%
5055120 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.71 54.0 5.36e-01 79.5% 93.9%
4960285 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.70 53.0 5.26e-01 79.5% 87.8%
3388201 264.2.1.1 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.68 51.0 4.91e-01 79.5% 88.5%
4990154 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.68 51.0 5.20e-01 79.5% 93.6%
4418351 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.68 53.0 5.44e-01 82.1% 92.4%
5005180 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.68 52.0 5.04e-01 81.2% 93.6%
4544551 264.2.1.1 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.67 51.0 5.03e-01 79.5% 89.2%
4031371 264.2.1.1 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.67 52.0 4.82e-01 81.2% 90.0%
4969403 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.67 51.0 4.85e-01 79.5% 85.4%
4981103 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.67 50.0 4.86e-01 78.6% 88.0%
5029441 264.2.1.1 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.66 51.0 4.98e-01 81.2% 90.0%
5070755 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.66 51.0 5.02e-01 83.0% 95.0%
4353811 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.65 36.0 4.48e-01 76.8% 87.1%
4990844 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.65 51.0 5.23e-01 82.1% 97.1%
5056966 264.2.1.1 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain › Topoisom_bac 0.65 49.0 4.85e-01 80.4% 89.2%
4336471 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.65 49.0 5.17e-01 79.5% 91.0%
4210460 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.64 50.0 4.97e-01 85.7% 96.7%
3692621 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.63 52.0 5.01e-01 90.2% 99.2%
5026373 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.63 48.0 4.83e-01 80.4% 93.6%
3590584 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.63 51.0 4.86e-01 89.3% 96.3%
4954871 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.62 48.0 4.79e-01 83.0% 100.0%
4956007 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.61 49.0 5.08e-01 87.5% 96.2%
5054962 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.61 47.0 4.65e-01 83.9% 97.5%
4940171 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.60 47.0 4.72e-01 84.8% 97.4%
3590914 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.60 47.0 4.80e-01 84.8% 100.0%
4836960 375.5.1.1 few secondary structure elements › Rubredoxin-like › NOB1 zinc finger-like › NOB1 zinc finger-like › NOB1_Zn_bind 0.56 28.0 3.31e-01 88.4% 69.0%
5016920 2.4.1.0 beta barrels › OB-fold › MOP-like › MOP-like 0.56 32.0 3.73e-01 76.8% 79.5%
4983766 2.4.1.1 beta barrels › OB-fold › MOP-like › MOP-like › TOBE 0.55 33.0 3.27e-01 76.8% 53.8%
4655745 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.54 41.0 4.35e-01 83.0% 97.0%
3404941 220.1.1.15 beta barrels › PH domain-like › PH domain-like › PH domain-like › BBL5 0.53 39.0 3.42e-01 76.8% 70.6%
5008812 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.53 41.0 4.27e-01 85.7% 97.1%
3355665 3863.1.1.1 beta barrels › Virulence associated protein B (Vapb) › Virulence associated protein B (Vapb) › Virulence associated protein B (Vapb) › Ysc84 0.53 43.0 3.52e-01 87.5% 50.7%
4002646 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.52 39.0 2.98e-01 78.6% 50.8%
4304505 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.51 33.0 3.22e-01 72.3% 56.2%
3438167 3863.1.1.1 beta barrels › Virulence associated protein B (Vapb) › Virulence associated protein B (Vapb) › Virulence associated protein B (Vapb) › Ysc84 0.51 40.0 3.43e-01 83.0% 55.0%
3596476 227.1.1.11 a+b two layers › DNA clamp › DNA clamp › DNA clamp › Hus1 0.50 36.0 3.38e-01 75.9% 74.8%
D3 high residues 264-375
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6k8nA02 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.85 80.0 7.88e-01 100.0% 100.0%
4cgyA04 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.84 80.0 7.65e-01 100.0% 93.6%
1cy9A01 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.80 74.0 7.27e-01 100.0% 93.2%
3bpvA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 40.0 3.69e-01 84.8% 43.1%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4976526 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.86 81.0 7.62e-01 99.1% 97.7%
5051951 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.85 80.0 7.60e-01 100.0% 93.8%
5021952 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.85 80.0 7.46e-01 100.0% 91.1%
3176697 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.85 80.0 7.24e-01 100.0% 93.1%
5000123 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.85 80.0 7.45e-01 100.0% 94.8%
4960284 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.85 80.0 7.68e-01 100.0% 94.4%
4987355 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.84 80.0 7.66e-01 100.0% 94.4%
3305633 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.84 80.0 7.65e-01 100.0% 94.4%
4981102 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.84 79.0 7.63e-01 100.0% 92.8%
4943299 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.84 79.0 7.61e-01 100.0% 95.2%
3590582 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.84 79.0 7.49e-01 100.0% 94.6%
4466579 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.84 79.0 7.44e-01 100.0% 94.6%
3756243 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.82 78.0 7.63e-01 100.0% 96.7%
4319228 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.82 77.0 7.27e-01 100.0% 93.8%
3594756 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.81 77.0 7.27e-01 100.0% 93.1%
5001225 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.81 77.0 7.13e-01 100.0% 92.6%
4006756 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.81 76.0 5.41e-01 100.0% 38.4%
4933036 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.81 76.0 7.30e-01 100.0% 92.0%
4073954 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.80 76.0 7.05e-01 100.0% 91.9%
5008811 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.80 76.0 7.15e-01 100.0% 93.1%
3593806 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.80 75.0 6.92e-01 100.0% 92.1%
5078217 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.79 57.0 6.15e-01 75.9% 86.3%
3612398 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.79 74.0 7.22e-01 100.0% 92.5%
5005179 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.78 73.0 7.02e-01 100.0% 94.4%
5023989 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.67 38.0 3.87e-01 88.4% 56.6%
D4 medium residues 153-200_488-555
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4cgyA02 1.10.460.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2 0.87 83.0 6.84e-01 100.0% 88.4%
1i7dA02 1.10.460.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2 0.83 76.0 6.43e-01 96.6% 94.4%
3bbzA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.73 30.0 4.44e-01 89.7% 91.7%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.71 44.0 5.12e-01 96.6% 87.8%
2ex3B02 1.20.1270.230 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › DNA terminal protein Gp3, priming domain 0.64 33.0 3.82e-01 98.3% 69.1%
7p2yC03 1.20.150.20 Mainly Alpha › Up-down Bundle › Lysin › ATP synthase alpha/beta chain, C-terminal domain 0.63 37.0 3.63e-01 94.8% 52.8%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 43.0 4.44e-01 100.0% 83.3%
3lcnB00 1.10.340.40 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain 0.57 43.0 4.58e-01 100.0% 95.9%
3rvyA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 38.0 3.96e-01 75.0% 84.1%
4xjvA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 45.0 3.79e-01 97.4% 92.1%
3mvcB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 36.0 3.29e-01 70.7% 78.6%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.51 41.0 3.79e-01 86.2% 79.5%
3w0lD02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.51 46.0 3.33e-01 100.0% 50.6%
4huqS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.50 40.0 3.62e-01 91.4% 61.6%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4990155 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.91 87.0 7.22e-01 100.0% 88.6%
4933038 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.88 84.0 7.07e-01 100.0% 89.4%
3180020 101.1.2.19 alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.88 84.0 6.97e-01 100.0% 90.8%
4943300 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.87 82.0 6.95e-01 100.0% 90.0%
2486892 140.1.1.9 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_3 0.62 44.0 3.87e-01 97.4% 50.0%
4117988 140.1.1.11 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 0.59 39.0 3.94e-01 95.7% 67.0%
3818391 109.46.1.2 alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › TPR1-like_2nd 0.58 45.0 4.42e-01 81.9% 90.4%
3746892 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.56 40.0 3.81e-01 100.0% 63.7%
3230714 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.54 36.0 3.98e-01 95.7% 86.7%
3802240 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.54 42.0 4.48e-01 100.0% 95.0%
3710353 148.1.3.12 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_8 0.53 35.0 3.64e-01 100.0% 70.0%
3586382 601.1.2.4 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.53 39.0 4.22e-01 100.0% 91.0%
3780893 592.1.1.0 alpha arrays › PWI domain-like › PWI domain › PWI domain 0.53 36.0 3.82e-01 78.4% 81.0%
3672657 3755.4.1.23 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF7032 0.51 40.0 3.66e-01 100.0% 63.3%
4988447 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.51 41.0 4.19e-01 100.0% 87.8%
5010018 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 43.0 3.75e-01 95.7% 76.8%