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IMGVR_UViG_3300014911_000368-3300014911-Ga0180301_100067196
Arc-VirIMGVR_UViG_3300014911_000368-3300014911-Ga0180301_100067196
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-39_150-224
Domain cluster:
rep: IMGVR_UViG_3300037454_000906-3300037454-Ga0394156_0000018_213093_213854__D8-56_178-240
CATH (58)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.76 | 52.0 | 5.14e-01 | 78.6% | 66.4% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.76 | 54.0 | 5.28e-01 | 82.1% | 68.3% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.75 | 49.0 | 4.88e-01 | 75.9% | 64.9% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 49.0 | 5.15e-01 | 74.1% | 73.8% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 51.0 | 5.20e-01 | 74.1% | 81.8% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 52.0 | 3.96e-01 | 77.7% | 66.4% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 48.0 | 4.33e-01 | 71.4% | 55.9% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 50.0 | 3.84e-01 | 75.0% | 76.3% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 49.0 | 4.59e-01 | 76.8% | 61.2% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 51.0 | 3.85e-01 | 77.7% | 80.9% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 50.0 | 4.02e-01 | 77.7% | 81.4% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 48.0 | 3.98e-01 | 75.0% | 81.1% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 41.0 | 4.31e-01 | 75.0% | 68.0% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.67 | 52.0 | 5.15e-01 | 85.7% | 78.2% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.66 | 54.0 | 4.59e-01 | 85.7% | 92.0% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.65 | 48.0 | 5.01e-01 | 83.9% | 82.4% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 47.0 | 3.50e-01 | 74.1% | 82.4% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.65 | 52.0 | 4.35e-01 | 85.7% | 90.2% |
| 1xl3C00 | 1.20.1280.80 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.65 | 38.0 | 4.13e-01 | 90.2% | 70.3% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.64 | 47.0 | 3.91e-01 | 78.6% | 43.5% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.63 | 46.0 | 3.84e-01 | 74.1% | 92.9% |
| 4fp4A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.63 | 55.0 | 4.29e-01 | 95.5% | 70.0% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 49.0 | 4.10e-01 | 84.8% | 83.5% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 44.0 | 3.98e-01 | 74.1% | 56.8% |
| 4hfvA01 | 1.20.1440.330 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 35.0 | 3.45e-01 | 79.5% | 51.3% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 49.0 | 3.68e-01 | 85.7% | 79.6% |
| 1blwC00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 41.0 | 3.79e-01 | 79.5% | 54.6% |
| 2h8oA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.61 | 52.0 | 3.86e-01 | 92.9% | 41.3% |
| 3aqbB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.60 | 51.0 | 3.70e-01 | 92.9% | 37.1% |
| 3ztaA00 | 1.10.490.130 | Mainly Alpha › Orthogonal Bundle › Globin-like › | 0.60 | 51.0 | 4.74e-01 | 91.1% | 92.1% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 46.0 | 5.08e-01 | 86.6% | 98.9% |
| 4nleA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.59 | 51.0 | 3.98e-01 | 97.3% | 57.4% |
| 3f0cA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 45.0 | 4.11e-01 | 80.4% | 64.6% |
| 3llwD00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.58 | 51.0 | 3.76e-01 | 95.5% | 43.9% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 40.0 | 4.32e-01 | 86.6% | 86.0% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.57 | 45.0 | 4.42e-01 | 91.1% | 78.0% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.57 | 44.0 | 4.72e-01 | 91.1% | 93.9% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.57 | 52.0 | 5.08e-01 | 100.0% | 97.5% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 38.0 | 4.26e-01 | 82.1% | 89.5% |
| 5uh5D02 | 1.10.132.30 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain | 0.56 | 32.0 | 3.02e-01 | 75.9% | 44.2% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 43.0 | 4.11e-01 | 81.2% | 96.2% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.56 | 50.0 | 4.05e-01 | 96.4% | 99.5% |
| 1v4eA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.56 | 47.0 | 3.58e-01 | 92.9% | 53.6% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.55 | 41.0 | 4.42e-01 | 86.6% | 90.6% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 47.0 | 4.40e-01 | 92.9% | 93.5% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 40.0 | 3.97e-01 | 87.5% | 73.5% |
| 1bgcA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 42.0 | 3.75e-01 | 82.1% | 64.6% |
| 1nigA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.53 | 48.0 | 4.34e-01 | 95.5% | 81.5% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 45.0 | 4.56e-01 | 91.1% | 90.9% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 44.0 | 4.04e-01 | 93.8% | 89.0% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 44.0 | 4.01e-01 | 94.6% | 89.7% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 39.0 | 3.63e-01 | 80.4% | 69.1% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 42.0 | 3.83e-01 | 86.6% | 66.7% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 46.0 | 4.15e-01 | 98.2% | 89.0% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 43.0 | 4.21e-01 | 90.2% | 86.8% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.51 | 41.0 | 4.22e-01 | 90.2% | 89.9% |
| 3fhnA01 | 6.10.280.210 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A | 0.51 | 35.0 | 3.03e-01 | 91.1% | 42.9% |
| 6h9dA00 | 1.10.530.40 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.50 | 43.0 | 3.95e-01 | 94.6% | 70.3% |
ECOD (64)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3838013 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.76 | 55.0 | 4.62e-01 | 81.2% | 46.1% |
| 3728487 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.72 | 52.0 | 4.30e-01 | 80.4% | 43.7% |
| 3988974 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.72 | 55.0 | 5.63e-01 | 84.8% | 81.8% |
| 3802509 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.72 | 49.0 | 4.41e-01 | 76.8% | 52.0% |
| 4101843 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.71 | 43.0 | 4.44e-01 | 74.1% | 63.8% |
| 3255232 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.71 | 53.0 | 4.05e-01 | 78.6% | 68.4% |
| 3216129 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.70 | 52.0 | 5.07e-01 | 77.7% | 69.6% |
| 3479389 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.70 | 57.0 | 4.81e-01 | 86.6% | 88.1% |
| 3703280 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.70 | 52.0 | 4.22e-01 | 77.7% | 46.2% |
| 3988973 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.70 | 53.0 | 5.24e-01 | 84.8% | 75.0% |
| 4934608 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.69 | 53.0 | 4.89e-01 | 79.5% | 66.4% |
| 4342803 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 53.0 | 5.40e-01 | 92.9% | 80.9% |
| 3189247 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 48.0 | 3.70e-01 | 70.5% | 75.2% |
| 3505505 | 5069.1.3.82 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7tm_3 | 0.69 | 54.0 | 5.34e-01 | 83.0% | 80.0% |
| 3267886 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.69 | 55.0 | 4.13e-01 | 84.8% | 80.0% |
| 3701003 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.68 | 50.0 | 4.51e-01 | 75.0% | 58.6% |
| 3936809 | 4177.1.1.3 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin | 0.68 | 57.0 | 4.45e-01 | 90.2% | 85.7% |
| 3746433 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.67 | 49.0 | 3.59e-01 | 75.0% | 63.2% |
| 3225375 | 601.1.3.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B | 0.67 | 54.0 | 4.78e-01 | 85.7% | 95.0% |
| 3962012 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.66 | 49.0 | 5.30e-01 | 92.0% | 89.5% |
| 3268765 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.66 | 51.0 | 3.97e-01 | 81.2% | 75.8% |
| 3254670 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.66 | 55.0 | 4.35e-01 | 89.3% | 88.0% |
| 3939680 | 4177.1.1.3 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin | 0.66 | 56.0 | 4.41e-01 | 92.9% | 81.7% |
| 3177985 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.65 | 55.0 | 4.25e-01 | 92.9% | 75.7% |
| None | — | 0.65 | 51.0 | 3.66e-01 | 83.0% | 49.8% | |
| 3215718 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.65 | 45.0 | 5.27e-01 | 77.7% | 100.0% |
| 4423640 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.64 | 52.0 | 3.67e-01 | 87.5% | 48.2% |
| 3454576 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.64 | 56.0 | 4.03e-01 | 96.4% | 56.1% |
| 3584009 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.64 | 49.0 | 3.80e-01 | 81.2% | 89.8% |
| 3919688 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.64 | 54.0 | 4.25e-01 | 92.9% | 79.2% |
| 3637538 | 601.1.2.63 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R | 0.64 | 51.0 | 4.23e-01 | 84.8% | 82.6% |
| 4014586 | 601.1.2.2 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ | 0.63 | 49.0 | 3.89e-01 | 81.2% | 69.1% |
| 3242356 | 605.4.1.19 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF30187 | 0.63 | 42.0 | 4.60e-01 | 74.1% | 84.4% |
| 4889682 | 11.2.1.20 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › FerB | 0.62 | 45.0 | 4.03e-01 | 86.6% | 55.6% |
| 3963743 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 50.0 | 5.16e-01 | 86.6% | 96.2% |
| 3213281 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.60 | 48.0 | 3.64e-01 | 84.8% | 83.7% |
| 3180874 | 604.1.1.57 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF2408 | 0.60 | 34.0 | 3.80e-01 | 76.8% | 70.0% |
| 3517735 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.60 | 47.0 | 3.92e-01 | 84.8% | 86.5% |
| 3581265 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 41.0 | 4.50e-01 | 85.7% | 87.8% |
| 3739454 | 192.5.1.38 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › NEDD4_Bsd2 | 0.59 | 46.0 | 4.72e-01 | 100.0% | 87.6% |
| 5071300 | 601.27.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › MW0975(SA0943)-like › MW0975(SA0943)-like | 0.59 | 46.0 | 3.97e-01 | 84.8% | 65.0% |
| 3696921 | 4177.1.1.14 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 | 0.58 | 51.0 | 3.72e-01 | 97.3% | 69.8% |
| 4345467 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.58 | 54.0 | 3.51e-01 | 100.0% | 47.6% |
| 4949745 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.58 | 54.0 | 4.02e-01 | 99.1% | 71.5% |
| 1581081 | 3017.1.1.1 ↗ | alpha bundles › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › PPV_E2_N | 0.58 | 41.0 | 4.42e-01 | 94.6% | 86.3% |
| 4518438 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.58 | 53.0 | 4.20e-01 | 100.0% | 89.5% |
| 3975106 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.57 | 51.0 | 3.80e-01 | 99.1% | 57.1% |
| 4114778 | 2004.1.1.525 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_27, SbcC_Walker_B | 0.56 | 48.0 | 3.07e-01 | 93.8% | 31.4% |
| 4011272 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 40.0 | 4.27e-01 | 90.2% | 85.0% |
| 3490233 | 109.26.1.6 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_NUP160_120_M | 0.55 | 49.0 | 3.99e-01 | 94.6% | 56.0% |
| 4020083 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.55 | 47.0 | 4.40e-01 | 92.9% | 87.1% |
| 4030302 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.55 | 46.0 | 4.37e-01 | 91.1% | 94.1% |
| 3480514 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.55 | 37.0 | 3.44e-01 | 92.9% | 53.1% |
| 5076586 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 43.0 | 4.58e-01 | 92.0% | 94.9% |
| 4033482 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.54 | 41.0 | 4.51e-01 | 88.4% | 98.9% |
| 3290040 | 174.1.1.61 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF29531 | 0.53 | 44.0 | 4.27e-01 | 89.3% | 91.2% |
| 4997380 | 3543.1.1.0 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel | 0.53 | 48.0 | 4.06e-01 | 98.2% | 64.4% |
| 4642297 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.53 | 45.0 | 4.29e-01 | 98.2% | 86.4% |
| 3705018 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 47.0 | 3.64e-01 | 100.0% | 49.0% |
| 3704641 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 46.0 | 3.56e-01 | 96.4% | 79.2% |
| 3500905 | 604.13.1.1 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer | 0.52 | 43.0 | 4.21e-01 | 100.0% | 80.8% |
| 3482466 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.51 | 45.0 | 3.80e-01 | 100.0% | 96.5% |
| 3623158 | 604.13.1.1 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer | 0.51 | 38.0 | 3.58e-01 | 86.6% | 65.2% |
| 3958445 | 109.4.1.2062 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_23 | 0.51 | 45.0 | 3.00e-01 | 96.4% | 38.4% |
D2
high
residues 42-147
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1z6tA04 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 32.0 | 3.53e-01 | 91.5% | 80.0% |
| 4bi3A01 | 3.90.1720.80 | Alpha Beta › Alpha-Beta Complex › endopeptidase fold (from Nostoc punctiforme) › | 0.50 | 32.0 | 3.40e-01 | 100.0% | 73.6% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3819664 | 2003.1.5.31 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS | 0.62 | 43.0 | 2.88e-01 | 70.8% | 81.5% |
| 3437079 | 2003.1.5.31 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS | 0.61 | 42.0 | 2.86e-01 | 70.8% | 80.5% |
| 4946822 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 31.0 | 3.46e-01 | 92.5% | 78.8% |
| 4044393 | 3121.1.1.1 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA | 0.51 | 28.0 | 3.29e-01 | 97.2% | 78.6% |
| 3374701 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.50 | 29.0 | 2.50e-01 | 94.3% | 32.8% |